Medicine and Health Sciences Commons^™

Longitudinal Reduction In Diversity Of Maternal Gut Microbiota During Pregnancy Is Observed In Multiple Low-Resource Settings: Results From The Women First Trial, Minghua Tang, Nicholas E. Weaver, Daniel N. Frank, Diana Ir, Charles E. Robertson, Jennifer F. Kemp, Jamie Westcott, Kartik Shankar, Sumera Aziz Ali, Sarah Saleem

Community Health Sciences

Objective: To characterize the changes in gut microbiota during pregnancy and determine the effects of nutritional intervention on gut microbiota in women from sub-Saharan Africa (the Democratic Republic of the Congo, DRC), South Asia (India and Pakistan), and Central America (Guatemala).
Methods: Pregnant women in the Women First (WF) Preconception Maternal Nutrition Trial were included in this analysis. Participants were randomized to receive a lipid-based micronutrient supplement either ≥3 months before pregnancy (Arm 1); started the same intervention late in the first trimester (Arm 2); or received no nutrition supplements besides those self-administered or prescribed through local health services (Arm …

Household Transmission Of Group A Streptococcus Necrotizing Fasciitis., Michael Markowitz, Stephanie Kwan, Jonas Matzon

Department of Orthopaedic Surgery Faculty Papers

A healthy 40-year-old woman was diagnosed with necrotizing fasciitis 2 days after her husband's death from the same infectious process. Prompt identification and immediate surgical intervention prevented a similar result in this patient. Additional investigation into both patients' medical records found the inciting organism to be group A streptococcus. Although the exact mechanism of inoculation is unknown, the spread of this infection within a household prompts the question of whether antibiotic prophylaxis should be given among close contacts in future cases of necrotizing fasciitis.

Narrative Inquiry Into Postsecondary Transition Outcomes For Young Adults With Intellectual & Developmental Disabilities, Eric R. Sarrett

Walden Dissertations and Doctoral Studies

Young adults with intellectual and developmental disabilities (IDD) continue to struggle with community engagement despite decades of research and policy initiatives addressing postsecondary transition. Evidence shows that persons with IDD are engaging in employment, postsecondary education, independent living, socialization, and other roles at significantly diminished rates, yet little data exists describing this participation in the voices of those affected. The purpose of this narrative inquiry was to describe community integration of persons with IDD in the decade following postsecondary transition in their own words. Critical disability theory was used as a lens to explore the successes and failures of public …

The Number Of Shoulder And Elbow Questions On The Orthopedic In-Training Examination Is Increasing With Greater Emphasis On Critical Thinking Over Recall, Suleiman Y. Sudah, Robert D. Faccone, Christopher R. Michel, Christopher N. Dijanic, Daniel J. Kerrigan, Mariano E. Menendez, Surena Namdari, Allen D. Nicholson

Rothman Institute Papers

Background: It is critical for orthopedic surgery residents and residency programs to have a current understanding of the content and resources utilized by the Orthopedic In-Training Examination (OITE) to continuously guide study and educational efforts. This study presents an updated analysis of the shoulder and elbow section of the OITE. Methods: All OITE questions, answers, and references from 2013 to 2019 were reviewed. The number of shoulder and elbow questions per year was recorded, and questions were analyzed for topic, imaging modalities, cognitive taxonomy, and references. We compared our data to the results of a previous study that analyzed shoulder …

Prevalence And Predictors Of Polypharmacy In Adolescents Who Have Engaged In Sexually Abusive Behaviors, Rebecca Gilley

Electronic Theses and Dissertations

Polypharmacy, or the concurrent use of multiple medications, is associated with detrimental outcomes for patients and has gathered increasing attention within the scientific clinical literature. Pediatric populations warrant special consideration for the practice of polypharmacy, as medication effects are more pronounced in youth and adverse effects may have a lasting impact on development. This dissertation study examined psychotropic prescribing practices in a sample of adolescents who have engaged in sexually abusive behaviors, a subset of justice-involved youth who are at risk for polypharmacy. General prescribing trends were examined, and a principle components analysis involving variables associated with risk of polypharmacy …

Trauma And Resilience Among Migrant Children From Mexico And The Northern Triangle Eroute To The United States, Georgina Sanchez-Garcia

Open Access Theses & Dissertations

Children who experience the phenomenon of migration from the Northern Triangle region and Mexico en route to the United States face pressing problems with psychosocial consequences that ostensibly affect them and are reflected in the violation of their human rights. We studied trauma and resilience among migrant children from Mexico and the Northern Triangle nations â??Guatemala, El Salvador, and Hondurasâ?? who are uprooted from their communities to undertake the dangerous overland journey to the United States (Lusk & Sanchez-Garcia, 2021; Rodriguez, 2020; UNICEF, 2018). The experience of such migration for children can be fraught with hardship, and it may have …

Case Report: Axilla Fibroadenoma - An Atypical Presentation, Safna Naozer Virji, Lubna Mushtaque Vohra, Syeda Sakina Abidi, Romana Idress

Department of Surgery Docs

No abstract provided.

Burnout And Wellness Strategies During The Covid-19 Pandemic, Cecilia Salinas Domene

MEDI 9331 Scholarly Activities Clinical Years

During the COVID-19 pandemic, healthcare workers not only had to manage how to treat a new disease but also had to increase their workload to keep up with the patients infected with the new virus. These physicians had to deal with an increase in patients and an increase in patient deaths. In addition, being a frontline worker meant that these physicians had more exposure to the virus than the general population. If they did contract the virus themselves, they had to go into quarantine, many times away from their families (Walton et al., 2020). A national survey done of physicians …

Knowledge Representation And Management: Notable Contributions In 2021, Licong Cui, Ferdinand Dhombres, Jean Charlet

Faculty, Staff and Student Publications

OBJECTIVES: To select, present, and summarize the best papers in the field of Knowledge Representation and Management (KRM) published in 2021.

METHODS: Following the International Medical Informatics Association (IMIA) Yearbook guidelines, a comprehensive and standardized review of the biomedical informatics literature was performed to select the best KRM papers published in 2021, based on PubMed queries.

RESULTS: A total of 1,231 publications were retrieved from PubMed. We nominated 15 candidate best papers, and four of them were finally selected as the best papers in the KRM section. The topics covered by these papers include knowledge graph, ontology development, ontology alignment, …

Charting The Proteome Landscape In Major Psychiatric Disorders: From Biomarkers To Biological Pathways Towards Drug Discovery, Brisa S Fernandes, Yulin Dai, Peilin Jia, Zhongming Zhao

Faculty, Staff and Student Publications

Schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD) are major mental disorders that affect a significant proportion of the global population. Advancing our knowledge of the pathophysiology of these disorders and identifying biomarkers are urgent needs for developing objective diagnostic tests and new therapeutics. In this study, we performed a systematic review and then extracted, curated, and analyzed proteomics data from published studies, aiming to assess the proteome in peripheral blood of individuals with SZ, BD, or MDD. Then, we performed pathway and network analyses to illuminate the biological themes concatenated by the differentially expressed proteins by systematically …

Genome-Wide Bidirectional Crispr Screens Identify Mucins As Host Factors Modulating Sars-Cov-2 Infection, Scott B Biering, Sylvia A Sarnik, Eleanor Wang, James R Zengel, Sarah R Leist, Alexandra Schäfer, Varun Sathyan, Padraig Hawkins, Kenichi Okuda, Cyrus Tau, Aditya R Jangid, Connor V Duffy, Jin Wei, Rodney C Gilmore, Mia Madel Alfajaro, Madison S Strine, Xammy Nguyenla, Erik Van Dis, Carmelle Catamura, Livia H Yamashiro, Julia A Belk, Adam Begeman, Jessica C Stark, D Judy Shon, Douglas M Fox, Shahrzad Ezzatpour, Emily Huang, Nico Olegario, Arjun Rustagi, Allison S Volmer, Alessandra Livraghi-Butrico, Eddie Wehri, Richard R Behringer, Dong-Joo Cheon, Julia Schaletzky, Hector C Aguilar, Andreas S Puschnik, Brian Button, Benjamin A Pinsky, Catherine A Blish, Ralph S Baric, Wanda K O'Neal, Carolyn R Bertozzi, Craig B Wilen, Richard C Boucher, Jan E Carette, Sarah A Stanley, Eva Harris, Silvana Konermann, Patrick D Hsu

Faculty, Staff and Student Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of symptoms in infected individuals, from mild respiratory illness to acute respiratory distress syndrome. A systematic understanding of host factors influencing viral infection is critical to elucidate SARS-CoV-2-host interactions and the progression of Coronavirus disease 2019 (COVID-19). Here, we conducted genome-wide CRISPR knockout and activation screens in human lung epithelial cells with endogenous expression of the SARS-CoV-2 entry factors ACE2 and TMPRSS2. We uncovered proviral and antiviral factors across highly interconnected host pathways, including clathrin transport, inflammatory signaling, cell-cycle regulation, and transcriptional and epigenetic regulation. We further identified mucins, a …

Real-World Matching Performance Of Deidentified Record-Linking Tokens, Elmer V Bernstam, Reuben Joseph Applegate, Alvin Yu, Deepa Chaudhari, Tian Liu, Alex Coda, Jonah Leshin

Faculty, Staff and Student Publications

OBJECTIVE: Our objective was to evaluate tokens commonly used by clinical research consortia to aggregate clinical data across institutions.

METHODS: This study compares tokens alone and token-based matching algorithms against manual annotation for 20,002 record pairs extracted from the University of Texas Houston's clinical data warehouse (CDW) in terms of entity resolution.

RESULTS: The highest precision achieved was 99.9% with a token derived from the first name, last name, gender, and date-of-birth. The highest recall achieved was 95.5% with an algorithm involving tokens that reflected combinations of first name, last name, gender, date-of-birth, and social security number.

DISCUSSION: To protect …

Development Of A Quality Improvement Dental Chart Review Training Program, Elsbeth Kalenderian, Nutan B Hebballi, Amy Franklin, Alfa Yansane, Ana M Ibarra Noriega, Joel White, Muhammad F Walji

Faculty, Staff and Student Publications

INTRODUCTION: Chart review is central to understanding adverse events (AEs) in medicine. In this article, we describe the process and results of educating chart reviewers assigned to evaluate dental AEs.

METHODS: We developed a Web-based training program, "Dental Patient Safety Training," which uses both independent and consensus-based curricula, for identifying AEs recorded in electronic health records in the dental setting. Training included (1) didactic education, (2) skills training using videos and guided walkthroughs, (3) quizzes with feedback, and (4) hands-on learning exercises. In addition, novice reviewers were coached weekly during consensus review discussions. TeamExpert was composed of 2 experienced reviewers, …

Review Curriculum Evaluation Of Physical Education Specialty Under The Perspective Of Teacher Training Certification, Gailing Han, Chunshan Zhu, Jie Cui

International Journal of Physical Activity and Health

The purpose of this study was to summarize the main body, content, method and application effects of physical education curriculum evaluation, to understand the current situation of physical education curriculum evaluation in China, and to construct an evaluation index system based on teacher training professional certification. The Chinese and English databases were searched by systematic evaluation, and the retrieval time was from December 31, 2018. The research literature that met the standard were included, and qualitative analysis was conducted by subject analysis method. A total of 100 studies were included, most of which summarized the concept, content and subject of …

The Relationship Between Physical Activity And Academic Performance Of Students, Haizhi Dai, Shuisheng Xu

International Journal of Physical Activity and Health

In China, many teachers and parents concern that physical activities take too much time of students, which would negatively influence students’ academic performance and the inescapable pressure of schools to produce students who meet academic standards. However, decreased physical activity participation due to the scarcity of exercises becomes prevalent in Chinese students. The correlation between students’ physical activity participation and academic achievement has raised increased attention. This study explored the relationship between students’ physical activity participation and academic performance from the perspective of humanities and sociology to explore a way to balance the two aspects for students. We conducted literature …

College Students’ Time Management Disposition, Self-Esteem And Mobile Phone Addiction: A Moderate Mediation Model, Ming Wu, Jian Yang, Yuan Yuan, Yuan Zhang

International Journal of Physical Activity and Health

The purpose of this study was to analyze the impact of time management disposition on mobile phone addiction, explore the mediating role of self-esteem, and examine the differences between active and inactive college students in this mediating role. 887 college students participated in this study with valid measures. According to physical activity rating scale (PARS-3), students who met the recommendations of the World Health Organization's Global recommendations on physical activity for health were categorized into active groups while the others were inactive group. The data was subjected to mediation model testing and multi-group comparison using Amos 21.0. The proportion of …

Correlation Between College Students' Physical Fitness And Running Habits, Mingming Guo, Xiaozan Wang

International Journal of Physical Activity and Health

The purpose of this study was to examine the correlation between the Physical Fitness of Chinese college students and their daily Running Habits (RH). A total of 718 college students from East China Normal University participated in this study (385 boys and 333 girls). Each participant participated in the Chinese Students’ Physical Fitness Test (CSPFT) during the 2018-2019 school year. In addition, each student was also required to use the APP to record all their running results during each run during the 2018-2019 school year. Researchers queried and exported all running records through the app's management platform. Correlation analysis was …

Experimental Research Of Body Functional Training On Promoting Physical Quality Of College Students, Songjian Du, Zhendong Zhang, Yingping Huang

International Journal of Physical Activity and Health

After being introduced into China, body functional training has been widely applied to the training of high-level athletes (Wang & Liu, 2014; Cui & Qiu, 2013). However, it is still in the exploratory stage in college teaching. In this research, body functional training was designed for the physical characteristics of ordinary college students, and the physical health status of students was monitored in order to understand the promoting effect of body functional training on college students' physical quality. It also provides theoretical and data support for the continuous improvement of body functional training courses. The research process was approved by …

Experimental Study On The Effectiveness Of Extracurricular Football Training For Improving Primary Students Physical Fitness, Yizhi Zhang, Xiaozan Wang, Mingming Guo

International Journal of Physical Activity and Health

The purpose of this study is to examine the effectiveness of after-school football training in improving the physical fitness of primary school students, so as to provide corresponding Suggestions for carrying out after-school football training in primary schools. A total of 72 students from the experimental primary school of Mouping district, Yantai city, Shandong province, participated in this experimental study, including 36 in the experimental group and 36 in the control group.The experiment was conducted for two semesters. During the experiment period, the experimental group conducted one-hour football training after school from Monday to Thursday afternoon every week, and two …

The Influence Of Intermediate Intensity Intermittent Cycle Training On College Students’ Fitness, Qinghua Guo, Jun Yang, Tian Gao, Jilong Yang

International Journal of Physical Activity and Health

Australia F45 functional training is a high-intensity intermittent cycle training method, integrating life, interest, competitiveness and cooperation together. The purpose of this study was to examine the effect of this training method on college students’ physical quality. 30 Participants from a university in southwest of China were recruited and were divided into two groups. The control group used traditional training methods while the experimental group used indirect circular training method, moderate intensity (pulse control at an average of 140-160 times / min), with the cooperation of music training. The corresponding fitness was tested before and 6 weeks after the experiment. …

Exploring Factors And Strategies To Promote Chinese Elders’ Physical Activity, Fanghong Yao, Rui Zhang

International Journal of Physical Activity and Health

This study was designed to explore factors and strategies to promote Chinese elders’ physical activity and cultivate healthy lifestyles. We collected the CHARLS survey 2011 baseline data, and selected 2647 cases of the elderly population in China. Based on the social ecosystem theory, the univariate analysis and ordered logistic regression were used. The model was analyzed for multivariate analysis. In the present study, the appropriate IRB approval has been obtained from Peking University. The theory of social ecology believes that individual behavior is influenced individual factors, inter-individual factors, organizational factors, community factors and policy factors. This article used the gender, …

Relationship Between Procrastination And Exercise Behavior Among College Students: The Mediating Effects Of Time Efficiency, Yuan Zhang, Jian Yang, Ming Wu, Yuan Yuan

International Journal of Physical Activity and Health

Procrastination is prevalent in the study and life of the college student population. There is evidence suggesting that procrastination can have a negative impact on mood and behavior. However, in the field of exercise, the effects and mechanisms of procrastination on exercise have not been widely studied. Therefore, this study investigates the relationship between procrastination and exercise volume of college students, and discusses the mediation effect of time efficiency. The sample comprised 910 university students from 5 provinces（female: 509, male: 401）who completed inventories assessing their procrastination, time efficiency and exercise volume, and the relationships between these variables were examined using …

Experimental Study On The Influence Of Kdl Physical And Health Education Curriculum On Primary School Students' Physical Fitness, Fan Wenrui, Wang Xiaozan, Guo Mingming

International Journal of Physical Activity and Health

Physical and Health Education Curriculum (KDL) is a curriculum based on China's Sports and Health Curriculum Standards and China's Health Sports Curriculum Model. This study aims to explore the influence of KDL on primary school students' physical fitness. A total of 91 primary school students participated in this study, including 47 in the experimental group and 44 in the control group. The experiment lasted for 18 weeks. During the experiment, the PE teacher of experimental group used KDL to teach, with specific requirements: (1) The activity time of each class was more than 75%, and the intensity, measured with average …

International Experience And Inspiration Of Online Physical Education In America Under The Crisis Of Public Health Emergencies, Han Meng, Zhihua Yin

International Journal of Physical Activity and Health

In recent decades, the frequent occurrence of public health crises has brought great challenges to teaching school physical education (PE). This study aims to improve the quality of PE online courses in China and provide effective support for PE teachers to carry out online teaching by learning from the experiences of how to effectively conduct online physical education in America when schools are closed. This study reviewed the relevant policy documents and literature of online physical education courses in America, including theoretical and practical studies. Furthermore, available data stemming from semi-structured interviews and focus groups with eleven PE teachers were …

Gender And Grade Differences In Knowledge And Behaviors Related To Active Living For Adolescents, Baofu Wang, Yang Liu, Stacy Imagbe, Senlin Chen

International Journal of Physical Activity and Health

The purpose of this study was to examine differences by gender and grade in middle school students’ physical activity and fitness (PAF) knowledge, physical activity, and sedentary behavior (SB). The study took place at one middle school located in the Southeastern region of the United States. Boys (n = 136) and girls (n = 166) in 6^th (n =129), 7^th (n = 96) and 8^th (n = 77) completed a PE Metrics written test to assess PAF knowledge. They (N = 312) also completed the validated Youth Activity Profile to report …

An Exploratory Study Of Strengthening Non-Dominant Side Of Exercises On Adhd Children In Primary Schools, Lu Chen, Xiaozan Wang, Meiyuan Chen, Xizhe Bai

International Journal of Physical Activity and Health

Empirical studies indicate that children with attention deficit hyperactivity disorder (ADHD) benefited significantly from exercise interventions. Further investigation shows that strength training of non-dominant limbs improves children's athletic ability and cognitive development. This study tested the effectiveness of a strength training intervention on non-dominant limbs for primary school children with ADHD, evaluating its impacts on children’s motor skills. In this experiment, 15 children with ADHD aged 6-10 years were recruited, including 12 boys and 3 girls. All meet the diagnostic criteria of the American Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) for ADHD. Randomly divided into age-matched experimental and …

The Training Theory Of Chinese University Sports Teams Based On The Complexity Paradigm, Zeyuan Wang, Zhendong Zhang, Haoxiang Sima

International Journal of Physical Activity and Health

Under the background of the integration of sports and education, it is of great significance to deepening the training theory of college sports teams. This research puts forward the necessity of using the complexity paradigm to find a more suitable training theory for college sports teams. The training theory of our country is deeply influenced by the simplicity paradigm. The simplicity paradigm is based on reductionism, which believes that the research object comprises simple addition of single elements, showing a linear relationship. There are many general pieces of training in the training arrangement, the preparation period is too long, the …

The Development And Practice Of Integrating Knowledge From Other Subject Matters Into Physical Education, Nengyan Wang

International Journal of Physical Activity and Health

To promote the curriculum integration of Physical Education (PE) with other school subject matters (such as Chinese, Math, English, etc.), this paper explored the effects of the curriculum integration on the teachers' and students' development of core literacy. Teachers and students from the two campuses of Sanjiaohu education groups participated in this study. Teachers and students from one campus served as the experimental group, and the other served as the control group. The integrated curriculum include the integrated curriculum of “martial art · art”, which derived from the integration among three levels of “martial art”, the related period music subject …

An Empirical Study On The Improvement Of Attention By Exercise Game Intervention In Children With Adhd, Xinyue Mao, Xiaozan Wang, Meiyuan Chen

International Journal of Physical Activity and Health

This study aims to verify the attention improvement of ADHD children after sports game intervention, and provide a green and safe intervention path to help ADHD children improve their attention. 16 children with ADHD (experimental group: 10, control group: 5) were selected to carry out exercise game intervention for 24 weeks, 4 times a week, each intervention lasted about 60 minutes. D2 attention test was carried out twice in the experimental group and the control group respectively to observe the attention of children, and the results of attention change in ADHD children before and after the intervention were analyzed. Data …

Research Progress And Future Prospect Of Dance Movement Therapy In China Based On A Citespace Visual Analysis, Haohui Liu, Zhihua Yin, Xue Wan

International Journal of Physical Activity and Health

The purpose of this study was to (1) explore the research progress of dance movement therapy in China and (2) reveal future development trend of dance movement therapy. With the methods of literature review, logical induction and scientific knowledge mapping, the research results of dance movement therapy in China were analyzed visually. The co-occurrence chart of key words and timeline analysis chart of key words of dance movement therapy in China were created based on the data. The co-occurrence chart of key words showed that the research hotspots centered on "dance therapy", "psychotherapy", "Parkinson's disease", "autism", "special children", "teenagers", "college …