Medicine and Health Sciences Commons^™

The Investigation Of The Taiwan Orthodontist Practice Behavior – Assistant Research, Tsui-Hsien Huang, Shiau-Lee Liew, Hung-Chih Chien, Yun-Ting Chen, Yi-Jyun Chen, Chia-Tze Kao

Taiwanese Journal of Orthodontics

The orthodontic specialty developed more than twenty five years in Taiwan. The orthodontic assistant system and its training are still not formed. The orthodontist’s clinical management and assistant interrelationship is less reported. The purpose of this study was to investigate the assistant role in orthodontic clinic. Totally one hundred and thirty two clinics were investigated. The assistant works and its correlated issue were calculated. The results showed most orthodontists allowed assistant works are including X ray taking, impression taking and oral hygiene education. The salary of the assistant that paid by orthodontists were ranged from 25000 to 40000 dollars. All …

Management Of Impacted Maxillary Central Incisors, Wen-Ching Tsai, Lin-Chan Lao

Taiwanese Journal of Orthodontics

Although the incidence of impaction of the upper central incisor is not so frequent, with about 0.06% to 0.2% incidence rate, the occlusal relationship and symmetric esthetics of upper anterior dentition are obviously affected. The patient’s psychology may also be altered while situation getting worse. Thus, the differential diagnosis and treatment modalities for impaction of upper central incisor should be emphasized. For the guidance of clinical treatment, the following text would focus on factors about impaction of upper central incisor including the etiology, diagnostic method, treatment principles, and also the post-treatment rehabilitation and retention.

Correction Of Unexpected Post-Surgical Anterior Open Bite With Miniscrew Orthodontics – Case Report, Sam Sheng-Pin Hsu, Yu-Fang Liao, Hsin-Yi Hsieh, Grace Ya-Ying Teng, Yi-Ting Chiang, Shih-Han Chen

Taiwanese Journal of Orthodontics

A case of anterior open bite with facial asymmetry is presented. The un-expected anterior open bite and retrusive mandible occurred shortly following orthognathic surgery (LeFort I - 3 pieces + Bilateral sagittal split osteotomy + genioplasty). The anterior open bite was then successfully corrected with miniscrew orthodontics.Possible causes of post-surgical anterior open bite and the treatment options were discussed comprehensively.

Cone-Beam Ct Facilitates The Diagnosis And Treatment Of An Orthodontic Case With Multiple Maxillary Anterior Teeth Impaction, Jhih-Wei Chen, Hui-Lin Chen, Chun-Liang Kuo

Taiwanese Journal of Orthodontics

Radiographic examination plays an important role in diagnosis and treatment of impacted tooth. However, conventional plain radiographic image is insufficient to provide enough information about impacted teeth in the case with multiple impacted teeth. Recently, cone-beam computed tomography and 3-D image are advanced and more details about impacted teeth and neighboring structure could be delineated from 3-D image. The detailed information will greatly improve the accuracy of diagnosis and implantation of an appropriate orthodontic treatment. This case report here presents a child with 3 impacted teeth in right anterior maxilla. With the aid of 3-D cone-beam CT image, 2 impacted …

The Investigation Of The Taiwan Orthodontist Practice Behavior, Shiau-Lee Liew, Hung-Chih Chien, Yun-Ting Chen, Yi-Jyun Chen, Chia-Tze Kao

Taiwanese Journal of Orthodontics

The orthodontic treatment is more popular at Taiwan in these twenty five years. The information of orthodontist’s clinic practice literature is few. The purpose of the present study was to investigate the orthodontists of Taiwan association of orthodontist (TAO) whose clinic practice behavior at north area of Taiwan. The investigations were done by the orthodontists answer on the questions. The questions were included administration of the clinic, the level of clinic computerized, the practice promotion and the influence of practice environment change. Totally one hundred and thirty two effects answer were recorded and calculated. The individually question outcomes were shown …

Changes In The Morphology Of Mandibular Symphysis Secondary To Pre-Surgical Dental Decompensation In Class Iii Malocclusion, Yu-Ching Wang, I-Ming Tsai, Hui-Ling Chen

Taiwanese Journal of Orthodontics

The purpose of this study is to evaluate the changes in morphology of mandibular symphysis in Class III malocclusion after pre-surgical dental decompensation. Thirteen patients underwent orthognathic surgery to correct Class III skeletal and dental malocclusions. The dental decompensation was indicated for these patients to gain greater setback amount of bilateral sagittal split ramus osteotomy. The morphology was assessed through lateral cephalograms obtained initially and preoperatively. After pre-surgical dental decompensation, the sagittal discrepancies were maintained. There was statistically significant lower incisor proclination, and both the FMIA and IMPA approximated the norms. When the mandibular incisors were labially inclined, the thinner …

The Historical Progress Of The Orthodontics, Part Ii, Te-Ju Wu, Wen-Ching Tsai

Taiwanese Journal of Orthodontics

In the end of 19th century, based on hard working of predecessors, orthodontics has more glory development; many orthodontic theory and appliances were displayed. Among them, Edward Angle,「The father of modern orthodontics」,played the most important role. Owing to his passion and devotion of orthodontics, the profile of orthodontics was getting more and more clear. There are so many conflicts and controversy during the development of orthodontics. However, it is the agitation that bring the orthodontics whole new appearance, also with the improvement of clinical efficiency, the orthodontics is getting more close to the need of patient and the ideal treatment …

The Historical Progress Of The Orthodontics, Part I, Te-Ju Wu, Wen-Ching Tsai

Taiwanese Journal of Orthodontics

The orthodontic treatment has become the popular choice while the public seeking for optimal occlusal function and esthetics. The discomfort accompanied with the treatment progress is gradually faded out by the post-treatment surprise. Taking a broad view, as the secret veil is lift off, the modern orthodontic treatment is chasing a whole new vision vigorously. However, as seeing the past, we should realize what we get now is not easily come by. Beginning from a division of oral medical science, the orthodontics is now regarded as a professional specialty. With the diversity, splash and the persistency for outstanding, the every …

Correction Of Mandibular Prognathism With Double- Jaw Surgery And Clockwise Rotation Of The Occlusal Plane- Case Report, Sam Sheng-Pin Hsu, Chiung-Shing Huang, Eric Jein-Wein Liou, Ellen Wen-Ching Ko, Clement Cheng-Hui Lin, Yu-Ray Chen

Taiwanese Journal of Orthodontics

An alternative surgical treatment plan was presented to show how to efficiently correct mandibular prognathism without large overjet discrepancy presented. The protrusive chin was eliminated through clockwise rotation of the occlusal plane and maxillo-mandibular complex. Within this method, no complicated orthodontic treatment was needed and the total treatment time was therefore shortened. The smiling arc was also improved. The philosophy, clinical application, long term stability, and side effects of the occlusal plane manipulation in orthognathic surgery were discussed.

Early Orthodontic Treatment For An Anterior Cross-Bite Malocclusion With Modified Hawley Appliance And 2×4 Fixed Appliance - A Case Report, Shang-Hung Tsai, Tzu-Hsin Lee

Taiwanese Journal of Orthodontics

The etiology of anterior cross-bite is multi-factor and the advocated treatment options were abundant. Early orthodontic treatments including chin-cap, face mask and palatal expansion have been recommended by many scholars. But some other clinicians would delay the orthodontic treatment combined with orthognathic surgery for Class III cases till the completion of growth, if there were no obvious detriment to patients’ oral function or psychological impact to their social life. However, for cases of non-skeletal anterior cross-bite (Pseudo-Class III) malocclusion, early orthodontic correction would be beneficial to normal maxillary forward growth and may prevent occlusal trauma of anterior teeth. This case …

The Possibility Of Acceleration In Orthodontic Tooth Movement, Yu-Jia Liou, Ellen Wen-Ching Ko, Eric Jein-Wein Liou, Betty Chien-Jung Pai

Taiwanese Journal of Orthodontics

In recent times, orthodontic treatment has attained significant interest and momentum. It has become more acceptable and admirable as a prime modality of treatment that not only enhances the facial esthetics but also can improve the function of the orofacial structures, than ever before. However, the layperson perceives it to be a treatment modality which consumes drastically longer period of time. Recent research pertaining to faster orthodontic tooth movement has dwelled in to this overwhelming area of reduced and more efficient treatment time. This review article specifically deals with such modalities of treatment which could elicit shorter treatment period than …

An Overview Of Motivation For Orthodontic Treatment, Hsin-Chung Cheng, Pei-Shuan Chen, Chun-Yi Kao, Chen-Chiou Chen

Taiwanese Journal of Orthodontics

Factors that affect the results of orthodontic treatment are various, and the understanding of motivation for orthodontic treatment is one of the most important because of its reference value in clinical diagnosis and treatment planning. In the past, there was just a few researches relating to this subject and most of them were conducted by questionnaire. Because of the differences methods of experimental design, the results varied. This review paper collect related articles in recent twenty years and analyze them in seven ways, including the definition of motivation, factors affecting orthodontic motivation, the relationship between orthodontic motivation and malocclusion and …

A Review Of The Relationship Between Facial Morphology In Vertical Dimension And The Masticatory Musculature, Yu-Ting Chiu, Wen-Ching Ko

Taiwanese Journal of Orthodontics

The orthodontic treatment philosophy and strategy toward patients with different vertical facial pattern such as open bite or deep bite, long face or short face, are usually different. The relationship between facial morphology in vertical dimension and masticatory musculature are always interested by orthodontists. However, the cause and effect relationship between muscle function and facial morphology is still inconclusive. To get a better understanding of previous works, this article mainly reviews the relationship between function and form into three aspects: bite force, cross-sectional area of muscle, orientation and mechanical advantage of muscle.

Tooth Transposition, Ya-Ting Wang, Jenny Zwei-Chieng Chang, Yi-Jane Chen, Chung-Chen Jane Yao, Eddie Hsiang-Hua Lai

Taiwanese Journal of Orthodontics

Tooth transposition is a big challenge for many orthodontists. We need more information and knowledge to diagnosis and plan treatment sequence correctly. However, let the teeth in the transposed position is sometimes the best choice after taking everything into consideration. But what is the etiology for teeth transposition？ How to diagnosis？Is there anything we could do to prevent teeth transposition？ All of these we would like to know. The purpose of this article is to review papers about tooth transposition. We hope it will be helpful for clinicians.

Orthodontic Molar Uprighting - Literature Review, Hsin-Yi Hsieh, Wen-Ching Ko, Chiung-Shing Huang

Taiwanese Journal of Orthodontics

Tipped molar is a relatively common occurrence in adult dentition. The objective in orthodontic molar uprighting is ideal positioning of the molar which will eventually become an abutment tooth for a fixed prothesis. The ideal position will improve the periodontal environment for the molar. The benefits provided by molar uprignting are: abutment preparations are simplified; pontic design is improved; reduced mesial periodontal infra-bony defect and so on. In present review article, several appliances and techniques are described for uprighting molars.

2022-08-17_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Establishing A Sustainable Occupational Therapy Student-Led Pro Bono Clinic At The University Of Saint Augustine In Austin, Texas, Daija Chumley

Student Capstone Papers

Under-resourced and underserved communities across the United States experience significant health disparities. These communities lack access to valuable services resulting in health inequities that impinge on their health, quality of life, and engagement in meaningful occupations. There is a need for occupational therapy to provide valuable services to the under-resourced and underserved community to address the historical inequity that impacts their overall quality of life. Universities have the potential to fulfill the gaps within these communities by establishing a pro bono clinic. The purpose of this capstone project is to establish a sustainable occupational therapy pro bono clinic at the …

2022-08-17_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/resources/covid-19-vaccine/covid-19-dashboard.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Primary Series Doses Administered, Primary Series Doses by Vaccine, …

Multiomic Analysis Reveals Cell-Type-Specific Molecular Determinants Of Covid-19 Severity, Sai Zhang, Johnathan Cooper-Knock, Annika K. Weimer, Minyi Shi, Lina Kozhaya, Derya Unutmaz, Calum Harvey, Thomas H. Julian, Simone Furini, Elisa Frullanti, Francesca Fava, Alessandra Renieri, Peng Gao, Xiaotao Shen, Ilia Sarah Timpanaro, Kevin P. Kenna, J Kenneth Baillie, Mark M. Davis, Philip S. Tsao, Michael P. Snyder

Faculty Research 2022

The determinants of severe COVID-19 in healthy adults are poorly understood, which limits the opportunity for early intervention. We present a multiomic analysis using machine learning to characterize the genomic basis of COVID-19 severity. We use single-cell multiome profiling of human lungs to link genetic signals to cell-type-specific functions. We discover >1,000 risk genes across 19 cell types, which account for 77% of the SNP-based heritability for severe disease. Genetic risk is particularly focused within natural killer (NK) cells and T¬†cells, placing the dysfunction of these cells upstream of severe disease. Mendelian randomization and single-cell profiling of human NK cells …

Advancing Treatment For Opioid Use Disorder In A Rural Emergency Department, Jill M. Wabbel

Doctor of Nursing Practice (DNP) Projects

Background: The opioid epidemic escalated in the United States due to the availability of prescription opioids, heroin, and synthetic opioids like fentanyl. Unfortunately, access to treatment is not always accessible, especially in rural communities with limited resources.

Local Problem: Tehama County is a rural county in northern California with limited access to treatment for opioid use disorder. The local Emergency Department (ED) and primary care-based Medication-Assisted Treatment (MAT) clinic collaborated to increase access. However, services remain under-actualized due to limited understanding of MAT best practices, stigma related to substance use within the ED culture, and poor articulation between the ED …

Impact Of Self-Care Techniques On Nurse Burnout, Macie Mayrell

MSN Capstone Projects

Nurse burnout is a serious, widespread problem in the healthcare arena. Registered nurses need to understand the importance of self-care to prevent or alleviate nurse burnout. An Evidence-Based Practice Benchmark Study implements a relaxation room on a nursing unit to encourage and promote self-care among acute care nurses.

The Impact Of Dieting Culture Is Different Between Sexes In Endurance Athletes: A Cross-Sectional Analysis, Austin J. Graybeal, Andreas Kreutzer, Jada L. Willis, Robyn Braun-Trocchio, Kamiah Moss, Meena Shah

Faculty Publications

Background: Frequent dieting is common in athletes attempting to achieve a body composition perceived to improve performance. Excessive dieting may indicate disordered eating (DE) behaviors and can result in clinical eating disorders. However, the current nutrition patterns that underly dieting culture are underexplored in endurance athletes. Therefore, the purpose of this study was to identify the sex differences in nutrition patterns among a group of endurance athletes.

Methods: Two-hundred and thirty-one endurance athletes (females = 124) completed a questionnaire regarding their dieting patterns and associated variables.

Results: The majority of athletes did not follow a planned diet …

Targeted Next-Generation Sequencing Of Congenital Hypothyroidism-Causative Genes Reveals Unexpected Thyroglobulin Gene Variants In Patients With Iodide Transport Defect, Carlos Eduardo Bernal Barquero, Romina Celeste Geysels, Virginie Jacques, Gerardo Hérnan Carro, Mariano Martín, Victoria Peyret, María Celeste Abregú, Patricia Papendieck, Ana María Masini-Repiso, Frédérique Savagner, Ana Elena Chiesa, Cintia E. Citterio, Juan Pablo Nicola

Pharmacy Faculty Articles and Research

Congenital iodide transport defect is an uncommon autosomal recessive disorder caused by loss-of-function variants in the sodium iodide symporter (NIS)-coding SLC5A5 gene and leading to dyshormonogenic congenital hypothyroidism. Here, we conducted a targeted next-generation sequencing assessment of congenital hypothyroidism-causative genes in a cohort of nine unrelated pediatric patients suspected of having a congenital iodide transport defect based on the absence of 99mTc-pertechnetate accumulation in a eutopic thyroid gland. Although, unexpectedly, we could not detect pathogenic SLC5A5 gene variants, we identified two novel compound heterozygous TG gene variants (p.Q29* and c.177-2A>C), three novel heterozygous TG gene variants (p.F1542Vfs*20, p.Y2563C, and …

Release Of Vocs, Gasses, And Bacteria From Contaminated Landings And Creeks Of Ogeechee River Basin, Victoria A. Clower, Melanie Sparrow, Atin Adhikari

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

River landings are common public grounds, visited by many people every day. The aftermath of visiting these places may be unsettling since much trash is left behind and scattered throughout. The litter collects and with each rain or high wind, it has a better chance of ending up in our streams, rivers, creeks, and eventually our oceans. The main purpose of this study was to measure both air and water quality throughout the Ogeechee River basin in South Georgia to determine how each was impacted by trash. Ammonia, methane, and volatile organic compounds (VOCs) along with temperature and humidity were …

Clinical Characteristics And Implications Of Bradycardia In Covid‐19 Patients Treated With Remdesivir: A Single‐Center Retrospective Cohort Study, Ariyon Schreiber, Justin S. Bauzon, Kavita Batra, Salman Mohammed, Kevin Lee, Nazanin Houshmand, Uyen Pham, Celica Cosme, Kim Inciong, Omar Al‑Taweel, Keaton Nasser, Jibran Rana, Chris Sossou, Ariel Go, Dalia Hawwass, Jimmy Diep, Chowdhury H. Ahsan

School of Medicine Faculty Research

Background and Objectives: Remdesivir is an antiviral drug used to treat coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac efect profle. Previous studies have reported bradycardia associated with remdesivir, but few have examined its clinical characteristics. The objective of this study was to investigate remdesivir associated bradycardia and its associated clinical characteristics and outcomes. Methods: This is a single-institution retrospective study that investigated bradycardia in 600 patients who received remdesivir for treatment of COVID-19. A total of 375 patients were included in the study after screening for other known causes of bradycardia (atrioventricular [AV] nodal blockers). All patients were …

Structure-Based Design Of Stapled Peptides That Bind Gabarap And Inhibit Autophagy, Hawley Brown, Mia Chung, Alina Üffing, Nefeli Batistatou, Tiffany Tsang, Samantha Doskocil, Weiqun Mao, Dieter Willbold, Robert C Bast, Zhen Lu, Oliver H Weiergräber, Joshua A Kritzer

Faculty, Staff and Student Publications

The LC3/GABARAP family of proteins is involved in nearly every stage of autophagy. Inhibition of LC3/GABARAP proteins is a promising approach to blocking autophagy, which sensitizes advanced cancers to DNA-damaging chemotherapy. Here, we report the structure-based design of stapled peptides that inhibit GABARAP with nanomolar affinities. Small changes in staple structure produced stapled peptides with very different binding modes and functional differences in LC3/GABARAP paralog selectivity, ranging from highly GABARAP-specific to broad inhibition of both subfamilies. The stapled peptides exhibited considerable cytosolic penetration and resistance to biological degradation. They also reduced autophagic flux in cultured ovarian cancer cells and sensitized …

Long-Term Effect Of A Gnrh-Based Immunocontraceptive On Feral Cattle In Hong Kong, Rebecca Pinkham, Ka-Kei Koon, Jason To, Jason Chan, Flavie Vial, Matt Gomm, Douglas C. Eckery, Giovanna Massei

United States Department of Agriculture Wildlife Services: Staff Publications

Increasing human-wildlife conflicts worldwide are driving the need for multiple solutions to reducing “problem” wildlife and their impacts. Fertility control is advocated as a non-lethal tool to manage free-living wildlife and in particular to control iconic species. Injectable immunocontraceptives, such as GonaCon, stimulate the immune system to produce antibodies against the gonadotrophin-releasing hormone (GnRH), which in turn affects the release of reproductive hormones in mammals. Feral cattle (Bos indicus or Bos taurus) in Hong Kong are an iconic species whose numbers and impacts on human activities have increased over the last decade. Previous studies have proven that a …

Long-Term Effect Of A Gnrh-Based Immunocontraceptive On Feral Cattle In Hong Kong, Rebecca Pinkham, Ka-Kei Koon, Jason To, Jason Chan, Flavie Vial, Matt Gomm, Douglas C. Eckery, Giovanna Massei

United States Department of Agriculture Wildlife Services: Staff Publications

Increasing human-wildlife conflicts worldwide are driving the need for multiple solutions to reducing “problem” wildlife and their impacts. Fertility control is advocated as a non-lethal tool to manage free-living wildlife and in particular to control iconic species. Injectable immunocontraceptives, such as GonaCon, stimulate the immune system to produce antibodies against the gonadotrophin-releasing hormone (GnRH), which in turn affects the release of reproductive hormones in mammals. Feral cattle (Bos indicus or Bos taurus) in Hong Kong are an iconic species whose numbers and impacts on human activities have increased over the last decade. Previous studies have proven that a …

Defining Hierarchical Protein Interaction Networks From Spectral Analysis Of Bacterial Proteomes, Mark A Zaydman, Alexander S Little, Fidel Haro, Valeryia Aksianiuk, William J Buchser, Aaron Diantonio, Jeffrey I Gordon, Jeffrey Milbrandt, Arjun S Raman

2020-Current year OA Pubs

Cellular behaviors emerge from layers of molecular interactions: proteins interact to form complexes, pathways, and phenotypes. We show that hierarchical networks of protein interactions can be defined from the statistical pattern of proteome variation measured across thousands of diverse bacteria and that these networks reflect the emergence of complex bacterial phenotypes. Our results are validated through gene-set enrichment analysis and comparison to existing experimentally derived databases. We demonstrate the biological utility of our approach by creating a model of motility in

Sars-Cov-2 Productively Infects Primary Human Immune System Cells In Vitro And In Covid-19 Patients, Marjorie C Pontelli, Sean P J Whelan, Et Al.

2020-Current year OA Pubs

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a hyperinflammatory state and lymphocytopenia, a hallmark that appears as both signature and prognosis of disease severity outcome. Although cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion, it is still unclear whether direct SARS-CoV-2 infection of immune cells could also play a role in this scenario by harboring viral replication. We found that monocytes, as well as both B and T lymphocytes, were susceptible to SARS-CoV-2 infection in vitro, accumulating double-stranded RNA consistent with viral RNA replication and ultimately leading to expressive …