Medicine and Health Sciences Commons^™

Topical Formulations Based On Polyhexamethylene Hydrochloride Guanidine For Surgicalfield Antisepsis, Fernanda Gosuen Gonçalves Dias, Renato Luis Tame Parreira, Lucas De Freitas Pereira, Rodrigo Cássio Sola Veneziani, Maria Anita Lemos Vasconcelos Ambrósio, Vinícius Thomaz Da Silva Almeida, Renata Alves De Barros, Luis Gustavo Gosuen Gonçalves Dias, Sérgio Ricardo Ambrósio

Turkish Journal of Veterinary & Animal Sciences

As surgical site infection can prolong the patient's hospital stay, increase morbidity and mortality rates and medical and hospital expenses, justifying the search for new effective and low-cost antiseptic drugs is justifiable. Thus, the objective of the present study was to analyze, by direct clinical and microbiological examination, the topical antiseptic effect of a solution based on polyhexamethylene hydrochloride guanidine (PHMGH) at 0.5% on the intact skin surface of sheep and cats, aiming at its use in operative field (previous and definitive antisepsis), compared to 0.5% alcoholic chlorhexidine and association with this. The topical solutions did not cause any skin …

Comparison Of M, Mm And Lts Estimators In Linear Regression In The Presence Of Outlier, Cem Tirink, Hasan Önder

Turkish Journal of Veterinary & Animal Sciences

In this study, it was aimed to evaluate the performance of different estimators that will be used in regression analysis, which is one of the multivariate statistical methods in the presence of outliers in the data set. Sixth month live weight was estimated with various body measurements for Saanen kids taken from a private farm. In the data set, the use and performance of robust estimators were evaluated because the least squares method did not provide reliable results in the case of outliers. M (for Huber and Tukey bisquare) estimator, MM estimator and LTS estimator were used as robust used …

A Biological Perspective On Interpreting Interaction Effect, Serdar Genç, Mehmet Mendeş

Turkish Journal of Veterinary & Animal Sciences

Factorial experiments are commonly employed in agricultural research as in other branches of applied sciences. In these experiments, inferences related to the interaction are essential. However, many researchers are still unable to analyze this type of experiment and interpret the results in the correct way. This is because researchers focus on interpreting the main effects although there is a significant interaction effect. Of course, meaningful main effects can exist even in the presence of an interaction, especially if interactions do not affect the main effects. Therefore, it is extremely important to understand thoroughly in which situations only the interaction effect(s), …

Do Horses Learn How To Reach For Feed Depending On The Time Of Day?, Agnieszka Ziemianska, Maciej Trojan, Konrad Bazewicz, Justyna Wojtas, Tomasz Próchniak, Iwona Rozempolska-Rucinska

Turkish Journal of Veterinary & Animal Sciences

The aim of the study was to assess the ability of horses to learn how to open feeder boxes in a direction associated with the time of day. The study involved 10 horses. The first stage of the study consisted in learning how to complete the task. The second stage involved the test and was followed by a control stage. The results indicated the highest number of failed attempts in the leftward movement test. The mean time required by the horses to complete the task of the leftward opening (10.27 s) was twofold longer than in the rightward direction test …

Temporospatial And Kinetic Gait Analysis In Aksaray Malaklı Shepherd Dogs, İsmai̇l Demi̇rci̇oğlu, Ozan Gündemi̇r, Yasi̇n Demi̇raslan, Gülşah Güngören, Nazan Gezer İnce, Bestami̇ Yilmaz

Turkish Journal of Veterinary & Animal Sciences

The present study aimed to determine the gait parameters of Aksaray Malaklı Shepherd dogs in order to identify the breedspecific gait characteristics and obtain the reference values for early diagnosis of the diseases. The force data were classified and analyzed based on plantar areas. For this purpose, 20 Aksaray Malaklı Shepherd dogs (10 females and 10 males) that were 18?36 months old were used. The dogs to be included in the study underwent a preliminary examination for lameness and the healthy ones were detected. Pressure-sensitive gait analysis system was used to obtain gait data. The dogs walked on the pressure …

The Efficacy Of Intravaginal Antibiotic Or Their Combination With Different Gonadotropins On Vaginitis And Fertility In Ewes Synchronized With Progesterone Impregnated Intravaginal Sponges, Bariş Güner, İhsan Kisadere

Turkish Journal of Veterinary & Animal Sciences

This study was conducted with two experiments to investigate the efficacy of intravaginal antibiotic or their combination with different gonadotropin use on vaginitis and the fertility in Berrichon ewes. All ewes (n = 106) were synchronized with intravaginal sponges containing 60 mg medroxyprogesterone acetate for 14 days. For the first experiment, ewes (n = 50) received 50 mg enrofloxacin (TRT) to sponge prior to insertion or received no treatment to sponge (CON) during nonbreeding season. For the second experiment, ewes (n = 56) were randomly assigned to one of the four groups (TRT-E; TRT-G; CON-E; CON-G) according to the presence …

Kid Growth Performance And Reproductive Characteristics Of Hair Goats Raised Under Breeder Conditions, Ayhan Ceyhan, Mahmut Çinar, Uğur Serbester

Turkish Journal of Veterinary & Animal Sciences

In the study, fertility parameters of Hair goats and the growth performance of kids raised under farmer conditions were investigated. The data of birth weight of 28,768 kids, the body weight of 27,541 kids aged d 90, and reproductive parameters of 26,693 does were used between 2013 and 2017 years. The birth weights of Hair goat kids born in 2013, 2014, 2015, 2016, and 2017 years were 2.36, 2.46, 2.56, 2.61, and 2.61 kg, whereas body weights detected on the d 90 were 15.2, 12.7, 12.8, 13.1, and 14.5 kg, respectively. Year, sex, birth type, and age of does affect …

A Stereological Study On Lumbosacral Segments Of Spinal Cord In The Geese, Gamze Çakmak, Zafer Soygüder

Turkish Journal of Veterinary & Animal Sciences

In this study, we aimed to determine the number, volume, and lumbosacral enlargement of the lumbosacral segments using stereology methods. In accordance with the study, 10 adult geese (regardless of sex) which were healthy and weighing 3-4 kg was chosen. After the geese had been perfused with 10% formaldehyde, the lumbosacral parts of their spinal cord were revealed by dissection. After each segment of the lumbosacral section had been separated, tissue samples were obtained from these segments. By means of a microtome, sections of 5-μm thickness were taken from the tissue samples. Then, twelve sections were obtained from a lumbosacral …

The Effect Of Different Ram Introducing Procedures (Protocol 66) On Fertility Parameters In Anatolian Merino Ewes During Breeding Season, Şükrü Dursun

Turkish Journal of Veterinary & Animal Sciences

In this study, different applications of ram introduction at the beginning of the breeding season were investigated in terms of their effects on some fertility parameters. The rams were introduced to the herd (Farm II), removed for 6 days, and reintroduced again in the experiment group, while the rams stayed within the herd (Farm I) all of the breeding season in the control group. In both farms, ewes were hand mated. These practices were performed in two consecutive breeding seasons of 2014 and 2015. In farm II, in the following 13 days of the reintroduction of rams, 83.4% and 83.7% …

Effects Of Pueraria Lobata Leaf Powder As A Feed Additive On The Immune System And Growth Performance Of Broiler Chickens, Jianping Gong, Dong Wu, Mengchu Li, Xiaoyu Qiu, Ying Jiang, Jie Zhang, Wenping Huang

Turkish Journal of Veterinary & Animal Sciences

The present research assessed the effect of different levels of Pueraria lobate leaf (PLL) on growth performance, immunity, antioxidant capacity, and blood index in broiler feed. A total of 384 at 21 days old chicks were assigned to 1 of 4 dietary treatments to examine the benefits of basal diet, basal diet +1% PLL, basal diet +2% PLL and basal diet +3% PLL. The trial was divided into 2 time periods, including starter from days 21-49 and finisher from days 50-70. The addition of 2% and 3% PLL powder to diets increased total protein content, triglycerides, albumin, and low-density lipoprotein …

Prevalence And Antibiotic Resistance Profiles Of Salmonella Spp. In Chicken Meat, Rabi̇a Telsaç, Rabi̇a Mehtap Tuncay

Turkish Journal of Veterinary & Animal Sciences

This study aimed to determine the Salmonella spp. presence in 100 chicken meat samples (25 breasts and 25 drumsticks with skin and 25 breasts and 25 drumsticks without skin) that were collected between February and April, 2021, in Van, Türkiye and investigate the antibiotic resistance profiles of the isolates. The results of the cultivation and PCR analysis revealed that a total of 17 samples comprising four drumstick with skin (16%), five drumstick without skin and breast without skin (20%), and three breast with skin (12%) samples were positive for Salmonella spp. The analysis of 17 chicken meat samples yielded a …

A Survey On Self-Medication For The Prevention Or Treatment Of Covid-19 And Distrust In Healthcare Of Veterans In A Primary Care Setting In The United States, Eva Amenta, Larissa Grigoryan, Laura Dillon, Casey Hines-Munson, John Van, Barbara Trautner

Faculty, Staff and Students Publications

BACKGROUND: The SARS-CoV-2 (COVID-19) pandemic brought the public overwhelming and conflicting information. Rates of trust in healthcare professionals have been declining among laypersons over the past five decades. In this setting, we sought to evaluate the use of medications, both with or without a prescription, to prevent and treat SARS-CoV-2 as well as trust in healthcare among patients in a primary care clinic.

DESIGN: We surveyed 150 veterans in primary care clinic waiting rooms at a large southwestern tertiary care Veterans Affairs hospital. This survey was performed in March-November 2021.

METHODS: The survey asked about respondents' demographics, use of medications, …

Clinical Reasoning Education In The Clerkship Years: A Cross-Disciplinary National Needs Assessment, Jonathan G Gold, Christopher L Knight, Jennifer G Christner, Christopher E Mooney, David E Manthey, Valerie J Lang

Faculty, Staff and Students Publications

BACKGROUND: Improving clinical reasoning education has been identified as an important strategy to reduce diagnostic error-an important cause of adverse patient outcomes. Clinical reasoning is fundamental to each specialty, yet the extent to which explicit instruction in clinical reasoning occurs across specialties in the clerkship years remains unclear.

METHOD: The Alliance for Clinical Education (ACE) Clinical Reasoning Workgroup and the Directors of Clinical Skills Courses (DOCS) Clinical Reasoning Workgroup collaborated to develop a clinical reasoning needs assessment survey. The survey questionnaire covered seven common clinical reasoning topics including illness scripts, semantic qualifiers, cognitive biases and dual process theory. Questionnaires were …

Health Disparities In Children And Adolescents Living In Lmic During Covid-19 Pandemic, Diane Nguyen, Satid Thammasitboon, Anna M Mandalakas

Faculty, Staff and Students Publications

PURPOSE OF REVIEW: The purpose of this editorial is to introduce the pediatric global health issue focusing on health disparities emerging from the COVID-19 pandemic on children and adolescents living in low- and middle-income countries (LMIC).

RECENT FINDINGS: As the COVID-19 pandemic ensues, children and adolescents living in LMIC have been disproportionately affected by socio-economic and mitigation practices, leading to widening disparities in health and the social determinants of health that influence their well-being.

SUMMARY: This pediatric global health issue brings to bare the extent, range, and nature of these health disparities, integrated with expert viewpoints, to prompt critical dialogue …

A Qualitative Study Of Emergency Department Delirium Prevention Initiatives, Anita Chary, Shan W Liu, Ilianna Santangelo, Kyler M Godwin, Christopher R Carpenter, Aanand D Naik, Maura Kennedy

Faculty, Staff and Students Publications

BACKGROUND: Delirium is a serious but preventable syndrome of acute brain failure. It affects 15% of patients presenting to emergency care and up to half of hospitalized patients. The emergency department (ED) often represents the entry point for hospital care for older adults and as such is an important site for delirium prevention.

OBJECTIVE: We sought to characterize delirium prevention initiatives in EDs in the United States and Canada.

METHODS: We conducted qualitative interviews with 16 ED administrators representing 14 EDs with delirium prevention initiatives. We used a combined deductive-inductive approach to code responses about involved staff, target patient population, …

Sustainability Of Breastfeeding Interventions To Reduce Child Mortality Rates In Low, Middle-Income Countries: A Systematic Review Of Randomized Controlled Trials, Alexis Engelhart, Stacey Mason, Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Victoria Carter, Thembekile Shato, Titilola Gbaja-Biamila, David Oladele, Juliet Iwelunmor

2020-Current year OA Pubs

Child mortality is the lowest it has ever been, but the burden of death in low- and middle-income countries (LMICs) is still prevalent, and the numbers average above the global mean. Breastfeeding contributes to the reduction of child mortality by improving chance of survival beyond childhood. Therefore, it is essential to examine how evidence-based breastfeeding interventions are being maintained in resource-constrained settings. Guided by Scheirer and Dearing's sustainability framework, the aim of this systematic review was to explore how evidence-based breastfeeding interventions implemented to address child mortality in LMICs are sustained. The literature search included randomized controlled trials (RCTs) of …

Job-Exposure Matrix: A Useful Tool For Incorporating Workplace Exposure Data Into Population Health Research And Practice, Alexis Descatha, Marc Fadel, Grace Sembajwe, Susan Peters, Bradley A Evanoff

2020-Current year OA Pubs

Workplace exposures to physical, chemical, and psychosocial factors account for a large burden of chronic diseases. Obtaining useful estimates of current and past workplace exposures is challenging, particularly in large general population studies. Job-exposure matrices (JEMs) are a useful tool for exposure assessment, particularly when no individual level exposure data are available. A JEM provides a cross-tabulation of job titles (sometimes combined with industry) and estimated exposures to workers carrying out these jobs during different time periods. The major limitation of JEMs is that they do not account for individual variation in exposures within the same job. This limitation is …

Preclinical Antibody-Pet Imaging Of Pd-L1, Emma L Brown, Rachel A Deweerd, Abbey Zidel, Patricia M R Pereira

2020-Current year OA Pubs

Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) blockade, including antibody therapeutics, has transformed cancer treatment. However, a major challenge in the field relates to selecting patients who are likely to respond to immune checkpoint inhibitors. Indeed, biopsy-based diagnostic tests to determine immune checkpoint protein levels do not accurately capture the inherent spatial and temporal heterogeneity of PD-L1 tumor expression. As a result, not all PD-L1-positive tumors respond to immunotherapies, and some patients with PD-L1-negative tumors have shown clinical benefits. In 2018, a first-in-human study of the clinically-approved anti-PD-L1 antibody Atezolizumab labeled with the positron emitter zirconium-89 validated the ability of positron emission …

Polypill For Atherosclerotic Cardiovascular Disease Prevention In Haiti: Eligibility Estimates In A Low-Income Country, Lily D Yan, Vanessa Rouzier, Jean Lookens Pierre, Eliezer Dade, Rodney Sufra, Mark D Huffman, Alexandra Apollon, Stephano St Preux, Miranda Metz, Shalom Sabwa, Béatrice Morisset, Marie Deschamps, Jean W Pape, Margaret L Mcnairy

2020-Current year OA Pubs

BACKGROUND: Multidrug therapy is a World Health Organization "best buy" for the prevention and control of noncommunicable diseases. CVD polypills, including ≥2 blood pressure medications, and a statin with or without aspirin, are an effective, scalable strategy to close the treatment gap that exists in many low- and middle-income countries, including Haiti. We estimated the number of Haitian adults eligible for an atherosclerotic CVD (ASCVD) polypill, and the number of potentially preventable CVD events if polypills were implemented nationally.

METHODS: We used cross-sectional data from the Haiti CVD Cohort, a population-based cohort of 3,005 adults ≥18 years in Port-au-Prince, to …

Conceptual Tensions And Practical Trade-Offs In Tailoring Implementation Interventions, Sheena M Mchugh, Fiona Riordan, Geoff M Curran, Cara C Lewis, Luke Wolfenden, Justin Presseau, Rebecca Lengnick-Hall, Byron J Powell

2020-Current year OA Pubs

Tailored interventions have been shown to be effective and tailoring is a popular process with intuitive appeal for researchers and practitioners. However, the concept and process are ill-defined in implementation science. Descriptions of how tailoring has been applied in practice are often absent or insufficient in detail. This lack of transparency makes it difficult to synthesize and replicate efforts. It also hides the trade-offs for researchers and practitioners that are inherent in the process. In this article we juxtapose the growing prominence of tailoring with four key questions surrounding the process. Specifically, we ask: (1) what constitutes tailoring and when …

The Human Myocardium Harbors A Population Of Naive B-Cells With A Distinctive Gene Expression Signature Conserved Across Species, Kevin C Bermea, Nicolas Kostelecky, Sylvie T Rousseau, Chieh-Yu Lin, Luigi Adamo

2020-Current year OA Pubs

INTRODUCTION: Cardiac immunology studies in murine models have identified a sizeable population of myocardial B-cells and have shown that its modulation represents a promising strategy to develop novel therapies for heart failure. However, scarce data on B-cells in the human heart leaves unclear whether findings in rodents are relevant to human biology.

METHODS: We performed immunohistochemical stains to characterize the amount and distribution of B-cells in human hearts, analyzing both fresh and post-mortem tissue. To gain insight into the biology of human myocardial B-cells we analyzed publicly-available spatial transcriptomics and single-cell sequencing datasets of myocardial and peripheral blood mononuclear cells …

Transient Equilibrium Determination Of Dopamine D2/D3 Receptor Densities And Affinities In Brain, Jenny-Ann Phan, Dean F Wong, Natalie H S Chang, Yoshitaka Kumakura, William R Bauer, Albert Gjedde

2020-Current year OA Pubs

Long-term alteration of dopaminergic neurotransmission is known to modulate the D

Socioeconomic, Clinical, And Molecular Features Of Breast Cancer Influence Overall Survival Of Latin American Women, Liz Maria De Almeida, Sandra Cortés, Marta Vilensky, Olivia Valenzuela, Laura Cortes-Sanabria, Mirian De Souza, Rafael Alonso Barbeito, Eliana Abdelhay, Nora Artagaveytia, Adrian Daneri-Navarro, Andrea S Llera, Bettina Müller, Osvaldo L Podhajcer, Carlos Velazquez, Elsa Alcoba, Isabel Alonso, Alicia I Bravo, Natalia Camejo, Dirce Maria Carraro, Mónica Castro, Sandra Cataldi, Alfonso Cayota, Mauricio Cerda, Alicia Colombo, Susanne Crocamo, Alicia Del Toro-Arreola, Raul Delgadillo-Cristerna, Lucia Delgado, Marisa Dreyer Breitenbach, Elmer Fernández, Jorge Fernández, Wanda Fernández, Ramon A Franco-Topete, Fancy Gaete, Jorge Gómez, Leivy P Gonzalez-Ramirez, Marisol Guerrero, Susan A Gutierrez-Rubio, Beatriz Jalfin, Alejandra Lopez-Vazquez, Dora Loria, Silvia Míguez, Andres De J Moran-Mendoza, Gilberto Morgan-Villela, Carina Mussetti, Maria Aparecida Nagai, Antonio Oceguera-Villanueva, Rui M Reis, Javier Retamales, Robinson Rodriguez, Cristina Rosales, Efrain Salas-Gonzalez, Laura Segovia, Juan M Sendoya, Aida A Silva-Garcia, Stella Viña, Livia Zagame, Beth Jones, Moysés Szklo, United States-Latin American Cancer Research Network (Us-Lacrn)

Faculty, Staff and Students Publications

Molecular profile of breast cancer in Latin-American women was studied in five countries: Argentina, Brazil, Chile, Mexico, and Uruguay. Data about socioeconomic characteristics, risk factors, prognostic factors, and molecular subtypes were described, and the 60-month overall cumulative survival probabilities (OS) were estimated. From 2011 to 2013, 1,300 eligible Latin-American women 18 years or older, with a diagnosis of breast cancer in clinical stage II or III, and performance status ≦̸1 were invited to participate in a prospective cohort study. Face-to-face interviews were conducted, and clinical and outcome data, including death, were extracted from medical records. Unadjusted associations were evaluated by …

The Transcriptomic Portrait Of Locally Advanced Breast Cancer And Its Prognostic Value In A Multi-Country Cohort Of Latin American Patients, Andrea Sabina Llera, Eliana Saul Furquim Werneck Abdelhay, Nora Artagaveytia, Adrián Daneri-Navarro, Bettina Müller, Carlos Velazquez, Elsa B Alcoba, Isabel Alonso, Daniela B Alves Da Quinta, Renata Binato, Alicia Inés Bravo, Natalia Camejo, Dirce Maria Carraro, Mónica Castro, Juan M Castro-Cervantes, Sandra Cataldi, Alfonso Cayota, Mauricio Cerda, Alicia Colombo, Susanne Crocamo, Alicia Del Toro-Arreola, Raúl Delgadillo-Cisterna, Lucía Delgado, Marisa Dreyer-Breitenbach, Laura Fejerman, Elmer A Fernández, Jorge Fernández, Wanda Fernández, Ramón A Franco-Topete, Carolina Gabay, Fancy Gaete, Adriana Garibay-Escobar, Jorge Gómez, Gonzalo Greif, Thomas G Gross, Marisol Guerrero, Marianne K Henderson, Miguel E Lopez-Muñoz, Alejandra Lopez-Vazquez, Silvina Maldonado, Andrés J Morán-Mendoza, Maria Aparecida Nagai, Antonio Oceguera-Villanueva, Miguel A Ortiz-Martínez, Jael Quintero, Antonio Quintero-Ramos, Rui M Reis, Javier Retamales, Ernesto Rivera-Claisse, Darío Rocha, Robinson Rodríguez, Cristina Rosales, Efrain Salas-González, Verónica Sanchotena, Laura Segovia, Juan Martín Sendoya, Aida A Silva-García, Alejandra Trinchero, Olivia Valenzuela, Vidya Vedham, Livia Zagame, United States-Latin American Cancer Research Network (Us-Lacrn);, Osvaldo L Podhajcer

Faculty, Staff and Students Publications

PURPOSES: Most molecular-based published studies on breast cancer do not adequately represent the unique and diverse genetic admixture of the Latin American population. Searching for similarities and differences in molecular pathways associated with these tumors and evaluating its impact on prognosis may help to select better therapeutic approaches.

PATIENTS AND METHODS: We collected clinical, pathological, and transcriptomic data of a multi-country Latin American cohort of 1,071 stage II-III breast cancer patients of the Molecular Profile of Breast Cancer Study (MPBCS) cohort. The 5-year prognostic ability of intrinsic (transcriptomic-based) PAM50 and immunohistochemical classifications, both at the cancer-specific (OSC) and disease-free survival …

An Introductory Point-Of-Care Ultrasound Curriculum For An Anesthesiology Residency Program, Susan C Lee, Edward C Yang, Jovany Cruz Navarro, Charles G Minard, Xiaofan Huang, Yi Deng

Faculty, Staff and Students Publications

INTRODUCTION: The use of point-of-care ultrasound (POCUS) is a growing trend in the field of anesthesiology. However, formal POCUS curriculums are still not widely implemented in residency programs. As the Accreditation Council for Graduate Medical Education and the American Board of Anesthesiology have both incorporated POCUS into their educational aims and expectations for graduates, we recognized the need for a formal POCUS curriculum for our residency program. We developed and implemented a comprehensive 3-week POCUS curriculum for our first-year anesthesiology residents (CA1s) in the latter half of their academic year.

METHODS: Twenty CA1s participated in this educational activity. The POCUS …

Management Of Perioperative Anticoagulation In A Patient With Antiphospholipid Antibody Syndrome Undergoing Cardiac Surgery: A Case Report, Sanjana A Malviya, Yi Deng, Sayyed O Gilani, Alec A Hendon, Melissa A Nikolaidis, Micah S Moseley

Faculty, Staff and Students Publications

Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB). In this case we present a patient with APLS and Immune Thrombocytopenic Purpura who successfully underwent aortic valve replacement (AVR) with CPB despite recent craniotomy for subdural hematoma evacuation. Anticoagulation for CPB was monitored by targeting an Activated Clotting Time (ACT) that was 2× the upper limit of normal. A multidisciplinary approach was essential in ensuring a safe and successful operation.

Exercise-Induced Myokines Downregulates The Ace2 Level In Bronchial Epithelial Cells: Implications For Sars-Cov-2 Prevention, Vaishali Bhardwaj, Mart Dela Cruz, Deepika Subramanyam, Rohit Kumar, Sandeep Markan, Beth Parker, Hemant K Roy

Faculty, Staff and Students Publications

BACKGROUND: The Covid-19 pandemic has emerged as the leading public health challenge of our time (20th century). While vaccinations have finally blunted the death rate, concern has remained about more virulent forms highlighting the need for alternative approaches. Epidemiological studies indicate that physical activity has been shown to decrease the risk of infection of some respiratory viruses. Part of the salutary effects of exercise is believed to be through the elaboration of cytokines by contracting skeletal muscles (termed myokines). The objective of this study was to investigate whether exercise-induced myokines would mitigate the SARS-CoV-2 infectivity of the bronchial epithelium through …

How Do Digital Lives Affect Resident Mental Health In The Digital Era? Empirical Evidence Based On Chinese General Social Survey, Yan Chen, Mengyang Wei, Jaime Ortiz

Faculty, Staff and Students Publications

Having good mental health means we are better able to connect, function, cope and thrive. The widespread application of digital technology in daily life provides new ways and promising tools for residents to maintain their mental health. Given the importance of mental health for everyone, and the fact that mental health problems are prevalent worldwide, this study discusses how digital lives affects the mental health of residents. The results suggest that digital lives are significantly and positively associated with mental health. Mechanisms analysis identifies personal perceptions (self-rated physical exercise and subjective wellbeing) as the important paths for digital lives to …

Sensory Descriptors For Three Edible Chilean Seaweeds And Their Relations To Umami Components And Instrumental Texture, Valentina Figueroa, Andrea Bunger, Jaime Ortiz, José Miguel Aguilera

Faculty, Staff and Students Publications

Although seaweeds exhibit many benefits as a food source, few studies have characterized their sensory attributes. An expert nine-member panel developed a vocabulary with 25 descriptors to describe the appearance, aroma, flavor, texture, and aftertaste of raw and cooked seaweeds consumed in Chile: Durvillaea antarctica, Pyropia spp., and Ulva lactuca. Subsequently, the vocabulary was used in a ranking descriptive analysis (RDA) to evaluate the sensory properties and relate them with physicochemical and physical data. Sensory attributes of the three seaweeds were very different from each other but similar between treatments (raw and cooked). Pyropia spp., both cooked and …

Evaluation Of The Khorana Score For Prediction Of Venous Thromboembolism In Patients With Multiple Myeloma, Kristen M Sanfilippo, Kenneth R Carson, Tzu-Fei Wang, Suhong Luo, Natasha Edwin, Nicole Kuderer, Jesse M Keller, Brian F Gage

2020-Current year OA Pubs

BACKGROUND: Guidelines recommend thromboprophylaxis for patients with multiple myeloma (MM) at high risk for venous thromboembolism (VTE). However, the optimal risk prediction model for VTE in MM remains unclear. Khorana et al developed a VTE risk score (Khorana score) in ambulatory cancer patients receiving chemotherapy. We aimed to evaluate the predictive ability of the Khorana score in patients with MM.

METHODS: We identified patients with MM within the Veterans Affairs health care system between 2006 and 2013. The Khorana score was calculated before treatment initiation. Using logistic regression, the relationship between risk group and VTE was assessed at 3 and …