Medicine and Health Sciences Commons^™

Prolonged Psychosis Before Onset Of Neurological Symptoms: An Atypical Clinical Manifestation Of Huntington’S Disease, Marium Mansoor, Nida Rahman Khan, Alviya Shaique

Pakistan Journal of Neurological Sciences (PJNS)

Huntington's disease (HD) is a rare, autosomal dominant, progressive neurodegenerative disorder. HD manifests with a triad of progressive motor, cognitive, and psychiatric symptoms. Our patient was a 39-years-old married female with over a nine-year history of psychotic symptoms. The patient was diagnosed and treated for schizophrenia. Over the last 2-3 years, the patient had a progressive decline in her Activities of Daily Living, instrumental activities of daily living, and psychotic symptoms. She developed slurred speech, gait disturbances, frequent falls, involuntary movements of the trunk and distal extremities, bowel and bladder incontinence, and severe weight loss. Her genetic test for Huntington’s …

A Case Of Ulcerative Colitis Presenting With Cerebral Venous Thrombosis, Zaid Waqar

Pakistan Journal of Neurological Sciences (PJNS)

Ulcerative Colitis is an autoimmune inflammatory bowel disease causing abdominal pain, bloody diarrhea and malnutrition and is associated with intestinal and extra intestinal complications. The clinical course has remissions and flare ups. Thromboembolism is a known risk associated with ulcerative colitis. Here we present a case of a young man who presented with a flare up of ulcerative colitis and developed neurological deficits that were diagnosed as due to cerebral venous thrombosis. Cerebral venous thrombosis is a rare complication of ulcerative colitis and can be missed without proper work up and consideration of diagnosis.

Options In The Treatment Of Subacute Sclerosing Panencephalitis: Implications For Low Resource Areas, Pauline Samia, Katherine Oyieke, Dorcas Tunje, Anaita Udwadia-Hegde, Kristen Feemster, Ibrahim Oncel, Banu Anlar

Paediatrics and Child Health, East Africa

Purpose of the review Subacute sclerosing panencephalitis (SSPE) is a rare, slowly progressive, and frequently fatal neurodegenerative disorder caused by measles virus. The risk of SSPE remains signifcant globally, with fuctuating incidence noted in in tandem with measles vaccine uptake. This review aims to explore the current global status of SSPE, its treatment, and preventive measures.

Recent findings An increase in measles cases have been reported in various parts of the world for different reasons related to the regional context of the outbreak. With reduction in measles vaccine doses since the onset of the COVID-19 pandemic, the future risk of …

A Case Report Of Minimally Invasive Percutaneous Ultrasound Guided Tuberculous Iliopsoas Abscess Drainage In An Immunocompromised Patient, Allyzain Ismail, Neelam Ismail, Authar Ali, Shabbir Adamjee, Ahmed Jusabani, Zainab Fidaali

Faculty of Health Sciences, East Africa

Introduction and importance

Iliopsoas abscess is a collection of pus that presents with nonspecific features with often delays in diagnosis however cause significant morbidity and mortality with Mycobacterium tuberculosis to be considered as causative agent in at risk individuals in tuberculous endemic regions. Management involves drainage and initiation of adequate antibiotics with radiological guided percutaneous approach considered the appropriate initial approach.

Case presentation

50-year-old immunosuppressed presenting with left iliopsoas abscess who underwent ultrasound guided drainage and placement of pigtail catheter successfully without the need for open surgical drainage. Our experience of interventional radiology for diagnosis of causative agent and treatment …

Nursing News & Views - March 2022, Joanne Miller Rn

Nursing Newsletters

No abstract provided.

The Athletic Identity Of Collegiate Athletic Trainers: A Descriptive Study, Christianne M. Eason, Stephanie H. Clines

Athletic Training Faculty Publications

Context: Empirical and anecdotal evidence suggest that many athletic trainers were former athletes and select the profession due to its affiliation with sport. Qualitative research has indicated that collegiate athletic trainers may have a strong athletic identity, but the concept of athletic identity has not been quantified in this population.

Objective: To quantitatively asses the athletic identity of collegiate athletic trainers and determine if group differences exist.

Design: Cross-sectional observational study.

Setting: Collegiate clinical setting.

Patients and other participants: A total of 257 (n = 93 (37%) males, n = 162 (63%) females) athletic trainers employed in the collegiate setting …

Tirofiban And Rivaroxaban Use In The Management Of Right Coronary Artery Thrombus As A Primary Manifestation Of Essential Thrombocythemia, Muhummad Nasir Rahman, Maleeha Javed

Section of Cardiology

A 45 year old male with hypertension was presented to our centre with a recent inferior wall myocardial infarction (IWMI) and post infarction angina. Invasive coronary angiography revealed an occluded proximal right coronary artery (RCA) with high thrombus burden, in the absence of obstructive disease in the remaining coronary vasculature. Based on raised platelet counts of 923,000/microliter and positive Janus kinase (JAK 2- V617) mutations tested by polymerase chain reaction (PCR), a diagnosis of essential thrombocythemia (ET) was made. A therapeutic strategy of aspiration thrombectomy along with I/V Tirofiban was used for three days, followed by reassessed angiogram and percutaneous …

Conflict With Peers: Delegate Task Among Team Members, Margaret Bove, Caius Coretchi, Margo Mekjian, Austin Piontkowski, Shatha Wahbi, Ho Jun Yun

Patient Education Projects

No abstract provided.

Effect Of Incorporation Of Hydroxyapatite Nanorods In Self-Etch Adhesive On Microtensile Bond Strength And Micromorphological Patterns Of Resin/Dentin Interface, Hameed K. Musa, Hamdi H. Hammama, Salah H. Mahmoud

Mansoura Journal of Dentistry

Objective: To evaluate microtensile bond strength (μTBS) of four types of adhesives including the “modified-bioactive” and their effect on micromorphological patterns of resin/dentin interface, immediately after 24hours and after 6months storage, followed by thermocycling. Material and Methods: Eighty extracted sound permanent molars were collected from patients seeking extraction in the outpatient clinic oral surgery department, Faculty of Dentistry at Mansoura University, according to the regulation of our institutional ethical committee under # (A03160321). The selected molars were assigned into four groups according to adhesive types: non-modified self-etch adhesive modified self-etch adhesive with hydroxyapatite nanorods, universal adhesive, resin-modified glass ionomer adhesive. …

Effect Of Platelet Based Preparation On Orthodontic Tooth Movement In Rabbits, Salma A. Mahmoud, Ahmed M. Fouda, Mohammed E. Grawish, Yasser L. Abdelnaby

Mansoura Journal of Dentistry

Objective: Autologous Platelet rich plasma (PRP) is used to accelerate orthodontic tooth movement, but its effect is still controversial. Materials and Methods: Twenty-eight male white Vienna rabbits were divided randomly into two main groups control and PRP. Each group included fourteen rabbits. Tooth movement was measured in seven rabbits from each group after 3 and 14 days respectively. Orthodontic tooth movement was generated by closed coil spring ligated between the mandibular first premolar and mandibular central incisors on both sides. The tooth movement was measured by measuring the space between mandibular first and second premolar using an orthodontic gauge and …

The Nine-Item Internet Gaming Disorder Scale (Igds9-Sf): Its Psychometric Properties Among Sri Lankan Students And Measurement Invariance Across Sri Lanka, Turkey, Australia, And The Usa, Amira Mohammed Ali, Rasmieh Al-Amer, Maha Atout, Tazeen Saeed Ali, Ayman M Hamdan Mansour, Haitham Khatatbeh, Abdulmajeed A. Alkhamees, Amin Omar Hendawy

School of Nursing & Midwifery

The prevalence of internet gaming disorders (IGD) is considerably high among youth, especially with the social isolation imposed by the ongoing COVID-19 pandemic. IGD adversely affects mental health, quality of life, and academic performance. The Internet Gaming Disorder Scale (IGDS9-SF) is designed to detect IGD according to DSM-IV diagnostic criteria. However, inconsistent results are reported on its capacity to diagnose IGD evenly across different cultures. To ensure the suitability of the IGDS9-SF as a global measure of IGD, this study examined the psychometric properties of the IGDS9-SF in a sample of Sri Lankan university students (N = 322, mean age …

Effectiveness Of Implementation Of Standard Clinical Pathway Through Healthcare Professionals Among Acute Myocardial Infarction Patients Undergoing Angiography / Angioplasty In A Public Tertiary Care Hospital, Karachi, Shahzad Bashir, Sarfraz Masih, Rubina Barolia, Muhammad Nawaz Lashari, Iram Amin

School of Nursing & Midwifery

Objective: To assess the effect of acute myocardial infarction standard clinical pathway among acute myocardial infarction patients on length of stay in public tertiary care setting.
Methods: The quasi-experimental non-randomised study was conducted at the Department of Cardiology, Dr Ruth Pfau Civil Hospital, Karachi, from September to December 2018, and comprised acute myocardial infarction patients. Those admitted before the implementation of acute myocardial infarction standard clinical pathway formed the control group, while those admitted after the implementation were in the intervention group. Acute myocardial infarction standard clinical pathway was implemented and the interventional clinical practices of healthcare professionals, including cardiologists, …

A Longitudinal And Cross-Sectional Study Of Plasma Neurofilament Light Chain Concentration In Charcot-Marie-Tooth Disease, Alexander Martin Rossor, Mahima Kapoor, Henny Wellington, Emily L Spaulding, James N. Sleigh, Robert W. Burgess, Matilde Laura, Henrik Zetterberg, Alexa Bacha, Xingyao Wu, Amanda Heslegrave, Michael E. Shy, Mary M. Reilly

Faculty Research 2022

Advances in genetic technology and small molecule drug development have paved the way for clinical trials in Charcot-Marie-Tooth disease (CMT); however, the current FDA-approved clinical trial outcome measures are insensitive to detect a meaningful clinical response. There is, therefore, a need to identify sensitive outcome measures or clinically relevant biomarkers. The aim of this study was to further evaluate plasma neurofilament light chain (NFL) as a disease biomarker in CMT. Plasma NFL was measured using SIMOA technology in both a cross-sectional study of a US cohort of CMT patients and longitudinally over 6‚Äâyears in a UK CMT cohort. In addition, …

Auditing: Does It Increase Fall Compliance?, Carly Williams, Clara Beaver, Catherine Cook

Conference Presentation Abstracts

Research has shown that compliance to universal fall protocols can reduce the incidence of falls for the inpatient population. The oncology population is at an increased risk for falls and falls with injuries, making adherence to fall precautions among this population especially crucial to patient safety. In 2020, there was an increase in patient falls and falls with injury at Karmanos Cancer Institute. This came after implementation of new fall protocols the previous year which resulted in a significant decrease in falls during 2019. The purpose of this project was to determine if auditing the compliance of fall prevention protocols …

Translating Evidence Into Impact: Enhancing Health In Francophone West Africa And The Sahel, Population Council

Research Utilization and Impact Briefs

Francophone West Africa (FWA) is a diverse subregion known for its strong national identities and regional collaboration. With high maternal and child death rates and low contraceptive prevalence compared to other parts of West Africa, Francophone countries have worked together to pursue common health and development goals, such as enhancing access to family planning/reproductive health; meeting the health, education, and employment needs of a growing population of young people; and addressing challenges such as climate change and conflict. Over the past three decades, the Population Council has worked to advance subnational, national, and regional efforts to improve health and promote …

Résumé Sur L’Utilisation Et L’Impact De La Recherche: Traduire Les Données Probantes En Impact: Améliorer La Santé En Afrique De L’Ouest Francophone Et Dans Le Sahel, Population Council

Research Utilization and Impact Briefs

L'Afrique de l'Ouest francophone (AOF) est une sous-région diversifiée connue pour ses fortes identités nationales et sa collaboration régionale. Avec des taux de mortalité maternelle et infantile élevés et une faible prévalence contraceptive par rapport à d'autres parties de l'Afrique de l'Ouest, les pays francophones ont travaillé ensemble pour poursuivre des objectifs communs de santé et de développement, tels que l'amélioration de l'accès à la planification familiale/santé reproductive ; répondre aux besoins en matière de santé, d'éducation et d'emploi d'une population croissante de jeunes ; et relever des défis tels que le changement climatique et les conflits. Au cours des …

Air Pollution In The Jfsb Parking Garage, Kara Law, Nathan Winward, Lucas Pettit, Emma Montague

Library/Life Sciences Undergraduate Poster Competition 2022

The purpose of this study was to characterize PM2.5 concentration in the JFSB parking garage compared to outdoor air on the JFSB’s balcony.

Effect Of Different Bevel Designs On Microleakage And Shear Bond Strength Of Class Iv Composite Restoration: A Laboratory Study, Hiran A. Qadir, Noha A. El-Wassefy, Asmaa M. Abdullah, Hamdi H. Hamama Associate Professor, Department Of Operative Dentistry, Faculty Of Dentistry, Mansoura University, Egypt

Mansoura Journal of Dentistry

Objective: This laboratory study was conducted to evaluate the effect of different bevel designs (2mm bevel, skirt bevel and scalloped bevel) on microleakage and shear bond strength of class IV composite restorations. Materials and Methods: Sixty extracted human permanent maxillary central incisors were selected and a standardized mesio-incisal fracture was created. Teeth were divided into 3 groups (n=20) according to different bevel designs (2mm bevel, skirt bevel and scalloped bevel). All prepared teeth were restored with nano hybrid composite (Filtek Z250, 3M ESPE, St. Paul, MN, USA). Half of specimens were used for microleakage test, specimens were received 3 layers …

Kemar Hats Head Orientation Directivity, Samuel D. Bellows, Timothy W. Leishman

Directivity

This directivity data set for a KEMAR head head-and-torso simulator (HATS) includes head orientations in 14 directions in 5° steps starting from 0° to 40° and then in 10° steps from 40° to 90°. The full spherical measurements followed at an a = 0.97 m radius with the mouth aperture at the spherical center. The sampling density and distribution followed the AES 5° dual-equiangular sampling standard, omitting the south pole (θ = 180°). Thus, each spherical directivity assessment included 36 polar-angle θ samples and 72 azimuthal-angle ϕ samples. The presented data include 22 1/3-octave bands, ranging from 80 Hz …

New Dentist News (March 2022), Ada Committee On The New Dentist

New Dentist News

New Dentist News offers timely information on scientific, social, educational, political and economic developments affecting new dentists. This collection is historical and items may not reflect current standards. For up-to-date information contact the ADA. The New Dentist News was alternately titled ADA Lifeline, 1997-June 2001.

Chronic Fatigue Predicts Hospital Nurse Turnover Intentions, Elizabeth Winokur, Dana N Rutledge, Sara Douville

Articles, Abstracts, and Reports

No abstract provided.

What Stops Us From Eating: A Qualitative Investigation Of Dietary Barriers During Pregnancy In Punjab, Pakistan, Muhammad Asim, Zarak Hussain Ahmed, Amy R. Nichols, Rachel Rickman, Elena Neiterman, Anita Mahmood, Elizabeth M. Widen

Community Health Sciences

Objective: Adequate dietary intake during pregnancy is vital for the health and nutritional status of both mother and fetus. The nutritional status of reproductive age women in Pakistan is poor, with 14 % being underweight (BMI < 18·5) and 42 % experiencing Fe deficiency anaemia. This may stem from beliefs, practices and other barriers influencing dietary intake. This qualitative study seeks to determine which factors impact dietary intake during pregnancy in rural Punjab.
Design: In-depth interviews and focus group discussions were conducted and then analysed using thematic analysis.
Setting: Three purposively selected rural districts (Sahiwal, Okara and Pakpatan) with the highest prevalence of maternal and child malnutrition in the province of Punjab, Pakistan.
Participants: Mothers with children under age two (n 29) and healthcare providers with at least 5 years of experience working in the district (n …

A Rare Benign Soft-Tissue Chondroma In The Plantar Foot: A Case Report, Ashley Mariano, Lawrence M. Fallat

Articles

Extraskeletal chondromas are rare, benign cartilaginous neoplasms that are usually found in adults and often present as a slow growing solitary mass. We present a case of a 78-year-old male who initially presented with a painful hyperkeratotic lesion to the plantar aspect of his right foot resembling a porokeratosis. He noted increased pain when bearing weight. Initial radiographs revealed no osseous pathology, bone spurs or foreign bodies that correlated with the area of pain. Due to failed conservative treatment that consisted of regular debridement, surgical excision of the lesion was performed which revealed a large underlying hard nodule. The nodular …

Tibiotalocalcaneal Fusion With Bulk Femoral Head Allograft In A Patient With A Rare, Trauma Induced, Rigid, Cavovarus Foot Deformity, Josh Carroll, Joseph Wolf, Lawrence M. Fallat

Articles

Tibiotalocalcaneal (TTC) arthrodesis with bulk femoral head allograft is a commonly performed limb salvage procedure when dealing with complex deformity. However, little has been reported in patients who receive tibiotalocalcaneal arthrodesis with femoral head allografts for a rigid cavovarus foot type. The purpose of this case report was to examine the outcomes of a tibiotalocalcaneal arthrodesis with a femoral head allograft in a diabetic patient with a trauma induced rigid cavovarus deformity who had complete lateral dislocation of the talar body. The secondary purpose was to highlight the preservation of limb length in the surgical extremity when utilizing a tibiotalocalcaneal …

N Y State Dent J March 2022

The New York State Dental Journal

In the March 2022 issue, the reader will find the following feature articles:

• Orthognathic Surgery and Quality-of-Life Outcomes: Findings from a Hospital-Based Patient Satisfaction Survey
• Recommendations for Co-Prescription of Opioids and Naloxone in the Dental Office
• Papillon-LeFevre Syndrome: A Case Study of Two Siblings
• Treatment of Peri-implant Soft-tissue Deficiency around a Narrow Diameter Implant with Subepithelial Connective-tissue Graft: A Case Report
• Simple Lipoma Mimicking Oral Infiltrating Lipoma: Case Report

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Hsp90 Inhibitors Modulate Sars-Cov-2 Spike Protein Subunit 1-Induced Human Pulmonary Microvascular Endothelial Activation And Barrier Dysfunction, Ruben Manuel Luciano Colunga Biancatelli, Pavel Solopov, Betsy W. Gregory, Yara Khodour, John D. Catravas

Bioelectrics Publications

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has caused more than 5 million deaths worldwide. Multiple reports indicate that the endothelium is involved during SARS-Cov-2-related disease (COVID-19). Indeed, COVID-19 patients display increased thrombophilia with arterial and venous embolism and lung microcapillary thrombotic disease as major determinants of deaths. The pathophysiology of endothelial dysfunction in COVID-19 is not completely understood. We have investigated the role of subunit 1 of the SARS-CoV-2 spike protein (S1SP) in eliciting endothelial barrier dysfunction, characterized dose and time relationships, and tested the hypothesis that heat shock protein 90 (HSP90) inhibitors would prevent and repair such injury. S1SP …

Cancer Incidence, Mortality, Years Of Life Lost, Years Lived With Disability, And Disability-Adjusted Life Years For 29 Cancer Groups From 2010 To 2019 A Systematic Analysis For The Global Burden Of Disease Study 2019, Ismaeel Yunusa Ph.D., Jonathan M. Kocarnik, Kelly Compton, Frances E. Dean, Weijia Fu, Brian L. Gaw, Et. Al.

Faculty Publications

Importance The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden.

Objective To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019.

Evidence Review The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite …

Inspire : Vol 5, Issue 3, Department Of Medicine

INSPIRE – Department of Medicine Archives

Content

• Medicine at National and International Forums
• World Congress - International Society of Nephrology (ISN)
• In-depth: featuring Manager Data Science – Mushyada Ali
• Featured Faculty – Dr Sonia Yaqub – Assistant Professor & Section Head- Nephrology section
• Poem section
• What are Academics Around the World Reading This Month?
• Publications
• Upcoming Events

Pharmacy Newsletter: March 2022, Pharmacy Department

Department of Pharmacy Archives

Content:

• Inhalers & Global emissions:
• Impact of Anticoagulation Management Clinics (AMC) at AKUH
• TOX TOK! A Poisonous Candy for the children: Mothballs (Phenyl ki Goli)
• Warfarin – A High Alert Drug

Implementing A Telephone Follow-Up Process For Patients With Poorly Controlled Type 2 Diabetes: A Nurse-Led Quality Improvement Project, Amber Gomes

DNP Projects

Background: Diabetes is the seventh leading cause of death in America with approximately 1.5 million people diagnosed yearly (ADA, 2020). The current problem in the practice setting is the lack of follow-up of patients with hemoglobin A1c’s (HbA1c’s) 9% or greater. The current workflow utilizes care coordinators to perform patient outreach to patients with diabetes and a HbA1c of 9% or greater. This workflow is not structured and consists of randomly selecting a patient with a HbA1c 9% or greater and placing one phone call to them to provide education.

Purpose: The purpose of the project was to develop and …