Medicine and Health Sciences Commons^™

An Evaluation Of A Web-Based Tool To Improve Feeding Practices And The Home Environment Among Parents Of Low-Income Minority Preadolescents At-Risk For Childhood Obesity, Katrina F. Mateo

Dissertations and Theses

Background: Web-based/mHealth interventions may be an engaging approach to promote positive dietary-related behaviors among parents of youth at-risk for childhood obesity. Importantly, childhood obesity research highlights the role of parents as a key support mechanism in improving child dietary outcomes. Intervention INC is a childhood obesity intervention that comprises a unique, interactive web-based child nutrition comic aimed at improving dietary behaviors among urban Black/African American (AA) and Latino preadolescents, and also weekly online parent newsletters (with feeding tips, healthy printable recipes, links to coupons to support healthy eating/feeding and health-promoting local/community events, and access to the child nutrition comic) to …

Low-Intensity Continuous Ultrasound For The Symptomatic Treatment Of Upper Shoulder And Neck Pain: A Randomized, Double-Blind Placebo-Controlled Clinical Trial, Stephanie Petterson, Kevin Plancher, Dominic Klyve, David Draper, Ralph Ortiz

All Faculty Scholarship for the College of the Sciences

Purpose: Low-intensity continuous ultrasound (LICUS) is an emerging high-dosimetry ultrasound-based therapy for accelerated tissue healing and the treatment of myofascial pain. In this study, LICUS treatment is clinically evaluated for chronic upper neck and shoulder pain in a randomized, multi-site, double-blind, placebo-controlled study. Patients and Methods: CONSORT guidelines were followed in conducting and reporting the clinical trial. Thirty-three participants with upper trapezius myofascial pain were randomized for treatment with active (n=25) or placebo (n=8) devices. Investigators and subjects were blinded to treatment groups. Participants self-reported pain daily, rating from 0– 10 on the numeric rating scale. If pain rating was …

2020-06-01/02 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Mari Anixter, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Jenny Situ, Alexandra Yingling, Kristine Tollestrup, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM Highlights: New public health order. First coronavirus death in state prison. NM case count. ABQ black lives matter protest. Santa Fe Fiesta canceled. U2 drummer donated to Navajo. US Highlights: Americans’ COVID-19 survey. Immunity for essential businesses in 4 states. International Highlights: Tiananmen Square closed to vigil. Shared approaches helpful for Africa. Economics, Workforce, Supply Chain, PPE: Face masks effective. Distance and Mask combined key to success. Economic effect on dental practice. Dow predicted to fall before new high. Epidemiology Highlights: Other causes of death increase. Virus not losing potency. Protests may spread virus. Wastewater surveillance. Healthcare …

Alteration Of Iron Responsive Gene Expression In Arabidopsis Glutaredoxin S17 Loss Of Function Plants With Or Without Iron Stress, Ninghui Cheng, Han Yu, Xiaolan Rao, Sunghun Park, Erin L Connolly, Kendal D Hirschi, Paul A Nakata

Children’s Nutrition Research Center Staff Publications

Iron (Fe) is a mineral nutrient and a metal cofactor essential for plants. Iron limitation can have detrimental effects on plant growth and development, while excess iron inside plant cells leads to oxidative damage. As a result, plants have evolved complex regulatory networks to respond to fluctuations in cellular iron concentrations. The mechanisms that regulate these responses however, are not fully understood. Heterologous expression of an Arabidopsis thaliana monothiol glutaredoxin S17 (GRXS17) suppresses the over-accumulation of iron in the Saccharomyces cerevisiae Grx3/Grx4 mutant and disruption of GRXS17 causes plant sensitivity to exogenous oxidants and iron deficiency stress. GRXS17 may act …

Associations Between Variations In Breast Anatomy And Early Breastfeeding Challenges, Alison K. Ventura, Brittany Lore, Olga Mireles

Kinesiology and Public Health

Background: Mothers with anatomic variability (e.g., shorter, wider nipples; denser areolas) may experience breastfeeding challenges disproportionately.

Research aim: To examine whether variations in breast anatomy are associated with risk for early breastfeeding challenges.

Methods: Participants included mothers < 6 weeks postpartum. Nipple base width, nipple length, and areolar density were measured on the right and left breast separately. Experiences with early breastfeeding challenges were determined through a combination of maternal report and clinical assessment.

Results: Participants (N = 119) had an average nipple diameter of 23.4 (SD = 3.0) mm for left nipples and 23.5 (SD = 3.0) mm for right nipples (range = 10–34 mm). Average nipple length was 8.5 (SD = 3.2) mm for left breasts and 9.1 (SD = 3.2) mm for right breasts (range = 5–20 mm); 35% of participants had dense areolas …

Risk Of Acute Kidney Injury In Patients Receiving Vancomycin And Piperacillin-Tazobactam Compared To Vancomycin And Cefepime, Viktoria Andonova

All Publications

No abstract provided.

Etomidate Use In Septic Patients Requiring Rapid Sequence Intubation, Elizabeth Osmon, Nishika Patel

All Publications

No abstract provided.

Ccdc61/Vfl3 Is A Paralog Of Sas6 And Promotes Ciliary Functions, Takashi Ochi, Huawen Lin, Susan K Dutcher, Et Al.

2020-Current year OA Pubs

Centrioles are cylindrical assemblies whose peripheral microtubule array displays a 9-fold rotational symmetry that is established by the scaffolding protein SAS6. Centriole symmetry can be broken by centriole-associated structures, such as the striated fibers in Chlamydomonas that are important for ciliary function. The conserved protein CCDC61/VFL3 is involved in this process, but its exact role is unclear. Here, we show that CCDC61 is a paralog of SAS6. Crystal structures of CCDC61 demonstrate that it contains two homodimerization interfaces that are similar to those found in SAS6, but result in the formation of linear filaments rather than rings. Furthermore, we show …

Evaluation Of Mavacamten In Symptomatic Patients With Nonobstructive Hypertrophic Cardiomyopathy, Carolyn Y Ho, Richard G Bach, Et Al.

2020-Current year OA Pubs

BACKGROUND: Patients with nonobstructive hypertrophic cardiomyopathy (nHCM) often experience a high burden of symptoms; however, there are no proven pharmacological therapies. By altering the contractile mechanics of the cardiomyocyte, myosin inhibitors have the potential to modify pathophysiology and improve symptoms associated with HCM.

OBJECTIVES: MAVERICK-HCM (Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy) explored the safety and efficacy of mavacamten, a first-in-class reversible inhibitor of cardiac-specific myosin, in nHCM.

METHODS: The MAVERICK-HCM trial was a multicenter, double-blind, placebo-controlled, dose-ranging phase II study in adults with symptomatic nHCM (New York Heart Association functional class II/III), left ventricular ejection fraction (LVEF) ≥55%, …

Analytical Setup Margin For Spinal Sbrt Based On Measured Errors, Audrey Copeland

LSU Master's Theses

Purpose: No consensus currently exists in the radiotherapy community about the correct margin size to use for spinal SBRT. Margins have been proposed to account for various errors individually, but not with all errors combined to result in a single margin value. The purpose of this work was to determine a setup margin for spinal SBRT based on known and measurable errors during radiotherapy to achieve at least 90% coverage of the clinical target volume (CTV) with the prescription dose for at least 90% of patients and not exceed a 30 Gy point dose or 23 Gy to 10% of …

Hericium Erinaceus: Erinacine A, Ventura Villanueva

Agricultural Education and Communication

Hericium erinaceus (Lion's Mane)

Erinacines - component found in Lion's Mane

A variety of mushroom that has been grabbing the attention of different pharmaceutical companies is the Hericium Erinaceus commonly known as Lion’s Mane. Lion’s Mane also known as, “Sheep’s head, Bear’s head, Bearded tooth carpophore, and Yamabushitmnnake” (Lion’s Mane (Hericium erinaceus)). Lion’s Mane in nature is found growing off the dry bark of trees (Kuo, 2016). Nowadays there are many products in the market that sell Lion’s Mane mushroom powder as a superfood. Lion’s Mane mushroom is known to have the component erinacines. Erinacines as of …

Enhancing Global Health Communication During A Crisis: Lessons From The Covid-19 Pandemic, Scott C. Ratzan, Silvia Sommarivac, Lauren Rauh

Publications and Research

Background/objective: The understanding and practice of public health crisis communication are improved through the study of responses to past crises, but require retooling for present challenges. The ‘Addressing Ebola and other outbreaks’ checklist contains guiding principles built upon maxims developed from a World Health Organization consultation in response to the mad cow (bovine spongiform encephalopathy) crisis that were later adopted for Ebola. The purpose of this article is to adapt the checklist for the health communication challenges and public health practices that have emerged during the coronavirus disease 2019 (COVID-19) pandemic. The communication challenges of promoting vaccine acceptance are used …

When Will I Get My Paper Back? A Replication Study Of Publication Timelines For Health Professions Education Research., Lauren A Maggio, William E Bynum, Deanna N Schreiber-Gregory, Steven J Durning, Anthony R. Artino

Health, Human Function, and Rehabilitation Sciences Faculty Publications

INTRODUCTION: Biomedical researchers have lamented the lengthy timelines from manuscript submission to publication and highlighted potential detrimental effects on scientific progress and scientists' careers. In 2015, Himmelstein identified the mean time from manuscript submission to acceptance in biomedicine as approximately 100 days. The length of publication timelines in health professions education (HPE) is currently unknown.

METHODS: This study replicates Himmelstein's work with a sample of 14 HPE journals published between 2008-2018. Using PubMed, 19,182 article citations were retrieved. Open metadata for each were downloaded, including the date the article was received by the journal, date the authors resubmitted revisions, date …

2020-06-01_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Measuring The Tourism Impact Of Covid-19, Singapore Management University

Perspectives@SMU

The initial lockdown in Wuhan in China’s Hubei province, the rise of infection cases and subsequent lockdowns in individual markets all contributed to a reduction in travel and booking activities, according to a new study conducted by The Chinese University of Hong Kong (CUHK). However, different regions showed different sensitivity to COVID-19.

Leading In The Time Of Covid-19, Singapore Management University

Perspectives@SMU

From planning well into the future to planning four weeks in advance, Ayala Corporation’s Chairman and CEO adjusted aggressively to navigate an unprecedented crisis.

Remaking Retail In The Time Of Covid-19, Singapore Management University

Perspectives@SMU

Short of the successful development of a COVID-19 vaccine, the sight of retail stores re-opening for business is probably the best mood lifter. Not only do lockdown-weary consumers reclaim some vestige of normalcy, businesses reeling from months of decimated income can stem the red ink and perhaps even get back into the black.

The Road Ahead For Global Supply Chains, Singapore Management University, Victor Fung

Perspectives@SMU

Technology, geopolitics, and COVID-19 could lead to a total reinvention of how goods move around the world

2020-06-01_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

Expression Of Poly-Adp-Ribose Polymerase (Parp) In Endometrial Adenocarcinoma: Prognostic Potential, Logan M. Lawrence, Rebecca Russell, Claire E. Denning, Nadim Bou Zgheib, Travis Salisbury, Seth T. Lirette, Jagan Valluri, Pier Paolo Claudio, Krista L. Denning

Faculty and Student Publications

© 2020 Background: In the United States endometrial carcinoma is the most common female gynecologic malignancy. An average of more than 60,000 new cases of endometrial carcinomas have been diagnosed yearly over the past 5 years, with a higher incidence occurring in the central Appalachian states of Ohio and West Virginia. In the U.S., the national average of newly diagnosed endometrial carcinomas is 26.8 in every 100,000 women, while in the states of Ohio and West Virginia the average is 30.5 and 31.1 in every 100,000 women, respectively. This notable increase in the incidence of endometrial carcinomas may be due …

Extracellular Matrix Components Isolated From Diabetic Mice Alter Cardiac Fibroblast Function Through The Age/Rage Signaling Cascade, Stephanie D. Burr, James A. Stewart

Faculty and Student Publications

© 2020 The Authors Individuals suffering from diabetes have an increased risk of developing cardiovascular complications such as heart failure. Heart failure can be a result of the stiffening of the left ventricle, which occurs when cardiac fibroblasts become “active” and begin to remodel the extracellular matrix (ECM). Fibroblast “activation” can be triggered by the AGE/RAGE signaling cascade. Advanced Glycation End products (AGEs) are produced and accumulate in the ECM over time in a healthy individual, but under hyperglycemic conditions, this process is accelerated. In this study, we investigated how the presence of AGEs in either non-diabetic or diabetic ECM …

Fluoroquinolone Versus Nonfluoroquinolone Treatment Of Bloodstream Infections Caused By Chromosomally Mediated Ampc‐Producing Enterobacteriaceae, Sarah Grace Gunter, Katie E. Barber, Jamie L. Wagner, Kayla R. Stover

Faculty and Student Publications

Objectives: Chromosomally mediated AmpC-producing Enterobacteriaceae (CAE) display high susceptibility to fluoroquinolones; minimal clinical data exist supporting comparative clinical outcomes. The objective of this study was to compare treatment outcomes between fluoroquinolone and nonfluoroquinolone definitive therapy of bloodstream infections caused by CAE. Methods: This retrospective cohort assessed adult patients with positive blood cultures for CAE that received inpatient treatment for 48 hours. The primary outcome was difference in clinical failure between patients who received fluoroquinolone (FQ) versus non‐FQ treatment. Secondary endpoints included microbiological cure, infection‐related length of stay, 90‐day readmission, and all‐cause inpatient mortality. Results: 56 patients were included in the …

Toxic Structures: Speculation And Lead Exposure In Detroit's Single-Family Rental Market, Alexa Eisenberg, Eric Seymour, Alex B. Hill, Joshua Akers

Urban Studies and Planning Faculty Research Publications

Foreclosure sales permitted investors to purchase large volumes of low-cost residential properties after the last financial crisis, reshaping patterns of property ownership in low-income housing markets across the US. This study links post-foreclosure property acquisitions by investor-landlords to subsequent lead poisoning cases among children under age six living in Detroit, Michigan. We find that the odds of exhibiting elevated blood lead levels (≥ 5 μg/dL) are higher for children living in investor-owned homes purchased through tax foreclosure sale. These findings highlight the potential for property speculation in post-foreclosure housing markets to exacerbate severe and racialized burdens of excess lead toxicity …

Identifying And Managing Substance Abuse In The Emergency Department, Nelsy M. Zuniga

College of Pharmacy Student Research

No abstract provided.

Covid-19: A New Chapter In The Loneliness Epidemic, Nancy Zhu

Social Space

We live in an era of increasing innovation and connectivity. It's said that we have the world is at our fingertips, with social media granting us the ability to link up quickly and easily with anyone across the globe. Yet the irony is that loneliness is a trusty companion in a modern and interconnected world.

Remembering Covid-19, Ellis Badger

Community Reflections

I have recently started working as an Occupational Therapist for Wellpath Recovery Solutions at Bridgewater State Hospital, a maximum security, forensics hospital, including working in the Covid 19 Unit.

Outside of work, I am able to spend a lot of time with my family, exercising, and woodworking. I keep in close contact with my classmates and we are always there for support through these tough times.

A Perspective On The Development Of Hemispheric Specialization, Infant Handedness, And Cerebral Palsy, Claudio L. Ferre, Iryna Babik, George F. Michel

Psychological Sciences Faculty Publications and Presentations

Cerebral Palsy (CP), a common form of neurological pediatric disability, results from pre- or perinatal brain injury. Although there is growing evidence of the efficacy of motor learning-based therapies, several factors interact to produce variability in impairment and limit the effectiveness of these therapies. The variability of hand function present in children with CP indicates that a range of developmental pathways must contribute to the manifestation of individually unique characteristics of impairment. Despite two decades of progress using therapies derived from understanding the mechanisms controlling hand function, very little is known about the sensorimotor experiences occurring during development that likely …

Reduced Expression Of The Pp2a Methylesterase, Pme-1, Or The Pp2a Methyltransferase, Lcmt-1, Alters Sensitivity To Beta-Amyloid-Induced Cognitive And Electrophysiological Impairments In Mice, Agnieszka Staniszewski, Hong Zhang, Kesava Asam, Rose Pitstick, Michael P. Kavanaugh, Ottavio Arancio, Russell E. Nicholls

Biomedical and Pharmaceutical Sciences Faculty Publications

Beta-amyloid (Ab) is thought to play a critical role in Alzheimer’s disease (AD), and application of soluble oligomeric forms of Ab produces AD-like impairments in cognition and synaptic plasticity in experimental systems. We found previously that transgenic overexpression of the PP2A methylesterase, PME-1, or the PP2A methyltransferase, LCMT-1, altered the sensitivity of mice to Ab-induced impairments, suggesting that PME-1 inhibition may be an effective approach for preventing or treating these impairments. To explore this possibility, we examined the behavioral and electrophysiological effects of acutely applied synthetic Ab oligomers in male and female mice heterozygous for either a PME-1 KO or …

Covid-19 And Procrastination: The Struggle To Stay Motivated In A Pandemic, Singapore Management University

Social Space

COVID-19 has led to the cancellation of countless internships, travel plans, summer jobs, music concerts and festivals, graduations, conferences, you name it. Fixed deadlines have become fluid, and both short-term and long-term goals are presently at the mercy of something far beyond our control. In the face of a global pandemic, we may find ourselves wondering, “Why bother planning for anything anyway?" Yet this very mindset is the crux of the coronavirus procrastination problem, says CHARDONNAY NEEDLER.

Cancer Pain And The Risks Of Opioid Abuse, Yarelis Diaz

College of Pharmacy Student Research

No abstract provided.