Medicine and Health Sciences Commons^™

Assessment Of Cognitive-Behavioral Symptoms And Functional Status Among Stroke Survivors, Chandel M, Shashi, Yashomati, Hemalata

Manipal Journal of Nursing and Health Sciences

Background: Stroke is one of the complex causes of death and disability. Stroke survivors often experience cognitivebehavioral and functional changes. Aim: The present study aims to assess the cognitive-behavioral symptoms and functional status among stroke survivors. Methods: A descriptive study was done in Neurology and Neurosurgery Out Patient Department of a tertiary care hospital in India. Consecutive 55 adult stroke survivors who were conscious and accompanied by the caregivers were included in the study. Standardized tools such as mini-mental status examination (MMSE), Neuropsychiatric Inventory Questionnaire (NIP-Q), and Barthel index were used to assess the cognitive, behavioral symptom, and functional status …

The Benefits Of Team Nursing, Diana Nguyen Bsn, Rn, Megan Hirschbul Bsn, Rn, Karly Jurewicz Bsn, Rn, Taylor Zerphey Adn, Rn

Vizient/ AACN Nurse Residency Program™ EBP Projects

No abstract provided.

Development And Maturation Of The Brain Following Pediatric Mtbi, Jeong Bin Lee

Loma Linda University Electronic Theses, Dissertations & Projects

Pediatric mild traumatic brain injury (mTBI) is a major public health concern with the potential to produce long-lasting cognitive, adaptive, and socio-behavioral outcomes. However, our understanding of how TBI pathophysiology evolves in the developing brain is lacking. Our central hypothesis was that pediatric mTBI results in evolving microstructural dysregulation that leads to functional and structural deficits late in life. To test this hypothesis, we first sought to assess the influence of pediatric mTBI on white matter (WM) dysregulation in early adulthood. To accomplish this, we investigated the effects of single and repeated pediatric mTBI on white matter, focusing on the …

Reply: There Are Limits To Autonomy., John W C Entwistle, Kathleen N Fenton

Department of Surgery Faculty Papers

No abstract provided.

Dimethyl Fumarate Suppresses Granulocyte Macrophage Colony-Stimulating Factor-Producing Th1 Cells In Cns Neuroinflammation., Farinaz Safavi, Rodolfo Thome, Zichen Li, Guang-Xian Zhang, Abdolmohamad Rostami

Department of Neurology Faculty Papers

Objective To study the immunomodulatory effect of dimethyl fumarate (DF) on granulocyte macrophage colony-stimulating factor (GM-CSF) production in CD4+ T cells in experimental autoimmune encephalomyelitis (EAE) and human peripheral blood mononuclear cells (PBMCs).

Methods We collected splenocytes and CD4+ T cells from C57BL/6 wild-type and interferon (IFN)-γ–deficient mice. For human PBMCs, venous blood was collected from healthy donors, and PBMCs were collected using the Percoll gradient method. Cells were cultured with anti-CD3/28 in the presence/absence of DF for 3 to 5 days. Cells were stained and analyzed by flow cytometry. Cytokines were measured by ELISA in cell supernatants. For in …

Exploring The Impact Of Insecure Attachment Styles In Couple Adjustment Through The Lens Of Cluster B Pathology, Laura Bonnemort

Dissertations

The current body of research literature appears to lack adequate studies focused on individuals who possess an insecure attachment, potential cluster B personality pathology, and who are engaged in couple discord. The following clinical research project explored how insecure attachments impact the trajectory of both cluster B pathology and adult couples’ relationship discord. Studies reviewed included adults diagnosed with mood disorders, personality pathology, and those engaged in couples therapy due to dissatisfaction and discord. Developing an insecure attachment in childhood appears to place adults at risk for higher rates of personality pathology and risky romantic relationships fraught with discord. Evidence-based …

Plant Based Extracts Show Novel Sanitising Effects Against Escherichia Coli On Romaine Lettuce And Cucumber, Tinashe Mandimutsira, Paul Tirivanhu, Constance Chingwaru, Walter Chingwaru

Chulalongkorn Medical Journal

No abstract provided.

Assessment Of Radiation Dose In Cardiac Ct Angiography Using Retrospective Ecg Gating Technique At Ramathibodi Hospital, Saifhon Admontree, Sawwanee Asavaphatiboon, Napapong Pongnapang, Anchali Krisanachinda

Chulalongkorn Medical Journal

No abstract provided.

Family Functioning And Associated Factors In Families Of Children And Adolescents With Chronic Illness At King Chulalongkorn Memorial Hospital, Dudaroon Limsawat, Thanvaruj Booranasuksakul, Taninee Sahakitrungruang

Chulalongkorn Medical Journal

No abstract provided.

Factors Affecting Sleep Quality In Acute Coronary Syndrome Survivors, Pattaranan Susuthi, Doungrut Wattanakitkrileart, Kanaungnit Pongthavornkamol, Chatkanok Dumavibhat

Chulalongkorn Medical Journal

No abstract provided.

Segmental Small Bowel Volvulus Caused By A Single Adhesion Band In A 5-Year-Old Girl: A Case Report, Sirima Liukitithara, Paisarn Vejchapipat

Chulalongkorn Medical Journal

No abstract provided.

Measuring The Impact Of Covid-19 On Older Adults In Massachusetts, Ceara Somerville, Jan Mutchler, Caitlin Coyle

Center for Social and Demographic Research on Aging Publications

The spread of COVID-19 across the United States has affected every facet of life since early 2020. According to the Centers for Disease Control and Prevention (CDC), there are currently over 4 million cases across the nation and over 146,000 deaths from the virus. Massachusetts has been one of the states hit hardest, with over 100,000 confirmed cases and more than 8,000 deaths to date. The Commonwealth currently trails only New York and New Jersey in number of deaths. While cases surge around the country, Massachusetts has seen some leveling out of positive cases since the beginning of July. Though …

Improving Skin Tears Healing Time Is Demonstrated By The Staff Rn Who Performs Early Initiation Treatment Of The Skin Tear Protocol, Sharon Brazile

Doctor of Nursing Practice Projects

Skin tears create numerous challenges for managing skin integrity for our aging population. Skin tears result from trauma, such as a patient bumping into a doorknob or rubbing against the wheelchair; they also occur because the epidermis and dermis lose elasticity and rub against each other, causing a shearing process that separates the outer skin layers from their protective under layers. Skin tears not only look terrible but can be painful and lead to infection if treatment is not initiated early by the nurse.

Purpose: The Chief Nursing Officer chose to focus on skin tear treatment at a southeast urban …

Increasing Long-Term Care Employee Influenza Compliance Through An Educational Approach, Shyandrea H. Brazil

Doctor of Nursing Practice Projects

Influenza (flu) is a highly contagious respiratory illness caused by several influenza viruses (Centers for Disease Control, 2019). The CDC estimates that there have been approximately 42.9 million flu incidents, 20.1 million flu medical visits, 647,000 flu related hospitalizations and 61,200 deaths from October 1, 2018 through May 4, 2019. Individuals who contract this illness may have symptoms varying from mild to severe. This project focused on the elderly population because these individuals fall into the high-risk category. Individuals 65 and older are more likely to experience flu-related complications, which could ultimately lead to hospitalizations and in some cases, death. …

Postoperative Myocardial Injury In A Patient With Left Ureteric Stone And Asymptomatic Covid-19 Disease, Nadeem Kassam, Omar Aziz, Ally Zain Ismail, Rodgers Swai, Samina Somji, Robert Mvungi, Mustaafa Bapumia, Ali Akbar Zehri, Salim Surani

Internal Medicine, East Africa

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It was first identified on 8thDecember 2019 in Wuhan, Hubei, China, and has since spread globally to become an emergency of international concern. Patients infected with SARS-CoV-2 may be asymptomatic or present with symptoms ranging from mild clinical manifestations: such as fever, cough, and sore throat to moderate and severe form of the disease such as pneumonia and acute respiratory distress syndrome (ARDS). In some patients, SARS-CoV-2 can affect the heart and cause myocardial injury which is evidenced either by electrocardiographic (ECG) changes …

The Effect Of Mechanical Vibration On Alveolar Bone Following Experimental Periodontitis: A Time Course Study, Joshua Murphy

Master's Theses (2009 -)

Introduction: High-frequency vibration with low magnitude acceleration has varying effects on alveolar bone. The objectives of this study were to establish a murine model for periodontitis and to explore the best time window of this model to investigate the effects of high frequency, low magnitude mechanical vibration on alveolar bone following ligature-induced experimental periodontitis. Materials and Methods: Ninety-five 11-week-old inbred strain C57BL/67 male mice were randomly assigned into four groups: 1) healthy control (n = 9); 2) healthy + mechanical vibration (n = 8); 3) experimental periodontitis + no treatment (n=7); and 4) experimental periodontitis + vibration (n = 9). …

Efficacy Of Invisalign: A Retrospective Case Series Of Intrusion, Extrusion, And Rotation With Trend Analysis, Kirsten Karkow

Master's Theses (2009 -)

Objective: To quantify efficacies and discrepancies of Invisalign® treatment of anterior intrusions, anterior extrusions, and incisor, canine and premolar rotations with correlations to age, gender, tooth, attachment, interproximal reduction, number of aligners, treatment time, and start date. Methods: Initial, progress, and final iTero® scans of patients treated with Invisalign® in the graduate Marquette University Orthodontics Clinic (Milwaukee, WI) were retrieved along with corresponding ClinChecks® as .stl files. These three-dimensional files were superimposed for best-fit using SlicerCMF4-0 software. A total of 67 anterior intrusions ≥ 0.5 mm, 39 anterior extrusions ≥ 0.5 mm, and 98 incisor, canine and premolar rotations ≥ …

Corrosion Properties Of Various Orthodontic Fixed Retention Wires, Tara Lynn Groen

Master's Theses (2009 -)

Objective: It is known that stainless steel and other alloys readily corrode in the oral environment. Many different wire compositions and configurations are available on the market for fixed orthodontic retainers, yet few studies have focused on the corrosion of wires used for fixed retention. The aim of this study was to determine the general and crevice corrosion properties of 7 distinct fixed retainer wires. Methods: Seven types of fixed retainer wires were chosen for testing – solid, braided and twisted stainless steel wires; solid and twisted gold plated wires; a solid cobalt chromium wire; and a solid beta-titanium ribbon. …

Anatomical Considerations For Miniplate-Anchored Maxillary Protraction In Children With Unilateral Cleft Lip And Palate, Jared Holloway

Master's Theses (2009 -)

Objective: The aim of this study was to explore the anatomical considerations of children with unilateral cleft lip and palate (UCLP) for the purpose of placing orthodontic miniplates for maxillary protraction. Materials and Methods: Cone beam computed tomography (CBCT) images of 41 patients with UCLP (18 females and 23 males with a mean age of 9.8) and 36 (19 females and 17 males with a mean age of 9.9) age-matched controls were assessed in this retrospective study. Multiple linear measurements were taken to evaluate the bone thickness of the infrazygomatic crest region (IZCR), buccal alveolar bone, and inferior portion of …

Tensile Strength Of Elastomeric Ligature Ties Stretched Over Large And Small Orthodontic Brackets, Golden Shiloh

Master's Theses (2009 -)

Objective: The purpose of this research was to investigate whether or not the larger required stretch of elastomeric ligature ties to secure an orthodontic wire into a larger sized bracket would lead to a more significant loss in tensile strength than if a smaller bracket size was used that required less of a stretch for placement of the elastomeric ligature. Methods: Maximum tensile strengths of elastomeric ligature ties from American Orthodontics and Dentsply Sirona were measured and compared after incubation for 4 weeks at 37±1oC under the following conditions: Unstretched dry, unstretched in artificial saliva, stretched and tied over a …

The Resilience Of Family Controlled Business Groups: Survival Of The Unfit, Nirmalya Kumar, Phanish Puranam

Research Collection Lee Kong Chian School Of Business

The COVID crisis has demonstrated that family controlled business groups, usually criticized as being inefficient and diverse, have higher survival rates for precisely these reasons.

Awareness Of And Willingness To Use Prep Among Black And Latinx Adolescents Residing In Higher Prevalence Areas In The United States, Tamara Taggart, Yilin Liang, Paolo Pina, Tashuna Albritton

Publications and Research

This mixed-methods study examined awareness of and willingness to use pre-exposure prophylaxis (PrEP) among sexually active Black and Latinx adolescents (13–17 years) residing in five cities in the United States with some of the highest burden of HIV. Data are from adolescents who participated in a cross-sectional survey (n = 208) and one-on-one interviews and focus groups (n = 26) conducted from September 2017—August 2019. Approximately 50% of the sample were recruited through community efforts, and the other half through a panel. Logistic regression with covariates including sexual orientation, relationship status, socioeconomic status, and race/ethnicity were used to assess factors …

Covid-19 Testnorm: A Tool To Normalize Covid-19 Testing Names To Loinc Codes, Xiao Dong, Jianfu Li, Ekin Soysal, Jiang Bian, Scott L Duvall, Elizabeth Hanchrow, Hongfang Liu, Kristine E Lynch, Michael Matheny, Karthik Natarajan, Lucila Ohno-Machado, Serguei Pakhomov, Ruth Madeleine Reeves, Amy M Sitapati, Swapna Abhyankar, Theresa Cullen, Jami Deckard, Xiaoqian Jiang, Robert Murphy, Hua Xu

Faculty, Staff and Student Publications

Large observational data networks that leverage routine clinical practice data in electronic health records (EHRs) are critical resources for research on coronavirus disease 2019 (COVID-19). Data normalization is a key challenge for the secondary use of EHRs for COVID-19 research across institutions. In this study, we addressed the challenge of automating the normalization of COVID-19 diagnostic tests, which are critical data elements, but for which controlled terminology terms were published after clinical implementation. We developed a simple but effective rule-based tool called COVID-19 TestNorm to automatically normalize local COVID-19 testing names to standard LOINC (Logical Observation Identifiers Names and Codes) …

Building A Contextually-Relevant Understanding Of Resilience Among African American Youth Exposed To Community Violence., Briana Woods-Jaeger, Emily Siedlik, Amber Adams, Kaitlin Piper, Paige O'Connor, Jannette Berkley-Patton

Manuscripts, Articles, Book Chapters and Other Papers

Studies consistently demonstrate that African American youth experience disproportionate levels of community violence, which is associated with negative health and well-being outcomes among these youth. The frequency and severity of community violence exposure is a unique challenge for these youth and requires tailored approaches to promote resilience after community violence exposure. However, limited research exists that operationalizes resilience after community violence based on the unique context and lived experience of African American youth. Developing a more contextually relevant understanding of resilience is critical to reducing health inequities experienced by African American youth and promoting their well-being. Five focus groups were …

The Public Health We Need, Alfredo Morabia

Publications and Research

No abstract provided.

Low Yield Of Hepatitis C Infection In An Outreach Screening Program In Harris County, Texas, Hyun-Seok Kim, Rosalia Guerrero, Shane W Reader, Maria Daheri, Maya Balakrishnan, Catherine L Troisi, Hashem B El-Serag, Aaron P Thrift

Faculty, Staff and Students Publications

A community outreach hepatitis C virus (HCV) infection screening program provided low yield of detecting HCV-infected patients, linking them to our hepatology clinic for treatment. Our data underscore that most of the yield was related to addiction centers and birth cohort; these groups should be targeted by future interventions.

Dental Light-Curing Units: An American Dental Association Clinical Evaluators Panel Survey, Kevin Frazier, Ana K. Bedran-Russo, Nathaniel C. Lawson, Jacob Park, Sharukh Khajotia, Olivia Urquhart

School of Dentistry Faculty Research and Publications

Background

The ability to polymerize light-activated dental materials with dental light-curing units (DLCUs) has revolutionized dentistry. However, proper DLCU use is essential for ensuring the effectiveness and performance of these materials.

Methods

The authors developed an electronic cross-sectional survey in the American Dental Association Qualtrics Research Core platform. The survey included questions about DLCU use, unit type and selection, training, maintenance, technique, and safety measures. The authors deployed the survey to 809 American Dental Association Clinical Evaluators (ACE) panelists on October 9, 2019, and sent reminder links to nonrespondents 1 week later. They conducted exploratory and descriptive analyses using SAS …

Synthesis And Characterization Of 3d-Printed Functionally Graded Porous Titanium Alloy, Ahmed Hindy, Farzam Farahmand, Fereydoun Pourdanesh, Maryam Torshabi, A. Hadi Al Janabi, Morteza Rasoulianboroujeni, Lobat Tayebi, Fahimeh Tabatabaei

School of Dentistry Faculty Research and Publications

This study aims to 3D print titanium alloy constructs incorporating gradient of porosities, from the fully dense core to the porous outer surface. Gradient porous specimens were prepared using selective laser melting (SLM). Fully dense specimens fabricated by SLM were used as the control group. Characterization of samples was done using X-ray tomography, uniaxial compression testing, and optical and scanning electron microscopes. The biocompatibility of fabricated samples was investigated using human periodontal ligament stem cells via assessment of cell attachment, viability, and proliferation by direct and indirect assays. The data were analyzed using ANOVA and Tukey’s post hoc test. Characterization …

Recent Advances In Designing 5-Fluorouracil Delivery Systems: A Stepping Stone In The Safe Treatment Of Colorectal Cancer, Elaheh Entezar-Almahdi, Soliman Mohammadi-Samani, Lobat Tayebi, Fatemeh Farjadian

School of Dentistry Faculty Research and Publications

5-Fluorouracil (5-FU) has become one of the most widely employed antimetabolite chemotherapeutic agents in recent decades. It is considered a first line antineoplastic agent for the treatment of colorectal cancer. Unfortunately, chemotherapy with 5-FU has several limitations, including its short half-life, high cytotoxicity and low bioavailability. In order to overcome the drawbacks of 5-FU and enhance its therapeutic efficiency, many scientific groups have focused on designing a new delivery system to successfully deliver 5-FU to tumor sites. We provide a comprehensive review on different strategies to design effective delivery systems, including nanoformulations, drug-conjugate formulations and other strategies for the delivery …

Microfluidic Fabrication Of Microcarriers With Sequential Delivery Of Vegf And Bmp-2 For Bone Regeneration, Erfan Dashtimoghadam, Farahnaz Fahimipour, Nikita Tongas, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Wound instability and poor functional vascularization in bone tissue engineering lead to lack of tissue integration and ultimate failure of engineered grafts. In order to harness the regenerative potential of growth factors and stimulate bone healing, present study aims to design multifunctional cell therapy microcarriers with the capability of sequential delivery of essential growth factors, bone morphogenetic protein 2 (BMP-2) and vascular endothelial growth factor (VEGF). An on-chip double emulsion method was implemented to generate monodisperse VEGF encapsulated microcarriers. Bio-inspired poly(3,4-dihydroxyphenethylamine) (PDA) was then functionalized to the microcarriers surface for BMP-2 conjugation. The microcarriers were seeded with mesenchymal stem cells …