Medicine and Health Sciences Commons^™

Dynamic Trajectory Generation And A Robust Controller To Intercept A Moving Ball In A Game Setting, Ravi Prakash, Laxmidhar Behera, Santhakumar Mohan, Sarangapani Jagannathan

Electrical and Computer Engineering Faculty Research & Creative Works

Complex and interactive robot manipulation skills, such as playing a game of table tennis against a human opponent, are a novel problem with multifaceted challenges. Accurate dynamic trajectory generation in order to respond to the tennis ball from the opponent and a novel control scheme for robust and high-performance tracking of the ball in such dynamic situations is a prerequisite to winning the game. In this paper, the dynamic movement primitives (DMPs) are employed for the stable generation of dynamic trajectories in the presence of environmental uncertainties such as ball position and velocity, opponent position and velocity and so on. …

Mitochondrial Contributions To Disuse Atrophy: Let’S Talk About Sex, Megan Rosa-Caldwell

Graduate Theses and Dissertations

Skeletal muscle atrophy is a hallmark of many pathologies and is associated with disease prognosis, quality of life, and mortality. Specifically, lack of contractile activity of the muscle can result in disuse-associated atrophy. Disuse-induced atrophy is a common phenomenon in intensive care unit (ICU) patients and significantly impacts patient prognosis and ability to transition of out of intensive care. However, effective therapeutics to mitigate disuse-associated atrophy do not exist, clearly demonstrating the scientific and clinical need to further understand mechanisms contributing to disuse atrophy. In particular, a significant portion of the scientific literature has utilized male models, yet there is …

Within-Person Variability Of Internal And External Sexual Consent, Malachi Willis

Graduate Theses and Dissertations

Background: Sexual consent is often conceptualized as an internal willingness to engage in sexual activity, which can be communicated externally to a sexual partner. Preliminary evidence indicates that people’s sexual consent varies from day to day. Study designs that assess sexual consent at multiple time points (e.g., experience sampling methodology [ESM]) are needed to better understand the within-person variability of sexual consent; however, extant validated measures of sexual consent are not appropriate for ESM studies, which require shorter assessments due to the increased burden this methodology has on participants. As such, the goal of this dissertation was to develop valid …

Effectiveness Of Ashtanga And Vinyasa Yoga: Combating Anxiety, Depression, Stress And Sleep Quality., Kati Street

Graduate Theses and Dissertations

Purpose: This lack of rigor in yoga research methodology hinders the understanding of yoga components and best practices. This study implements two yoga interventions with recommended adequate structure, one more physically demanding (Ashtanga Vinyasa) and a less physically demanding (slow flow vinyasa). The instructor, who is also the lead researcher, developed a slow flow vinyasa sequence and modified the set sequence of Ashtanga Vinyasa for beginners. Both yoga interventions cover domains suggested by Sherman (2012) for meticulous methods in yoga research.

Methods: This study implements two styles of yoga with university students over the course of eight weeks, meeting twice …

J Mich Dent Assoc July 2020

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association brings news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. No publication reaches more Michigan dentists!

In this issue, the reader will find the following original content:

• A cover story, “Infection Control Checklist for Dental Offices” that offers a user-friendly checklist to help dental team members comply with current infection control regulations and guidelines, using the most recently available science- and clinical-based evidence gathered from multiple health professional resources.
• A feature story on “Minimizing Aerosols with Non-Surgical Approaches to Caries Management".
• “Evidence-Based …

Polycystic Ovarian Syndrome: Causes, Complications, And Treatments, Toni Tornberg

Biomedical Sciences Undergraduate Research

Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder prevalent in 6-10% of reproductive age women. The purpose of this review paper is to describe both genetic and environmental causes and symptoms of PCOS. Additionally, to summarize the complications women face with a PCOS diagnosis and present treatment and management options. The information forming this paper was compiled from various online heath journals. The results show that both clinical and biochemical examinations are used for the diagnosis of PCOS while the exact cause is unknown. Genetics and environmental factors, specifically the intrauterine environment, are discussed as causes. Management and treatment options …

Microbial Experience Influences Tumor- Infiltrating T Lymphocytes, Hanna Groeber

Masters Theses

Immune cells, including T cells, have been used for anti-cancer therapy with varying degrees of success. One potential reason for immunotherapy failures in clinical trials may be that typical specific pathogen free (SPF) mice do not accurately replicate human microbial experience, which has important influence on shaping the adaptive immune response. Recently, several previous studies have shown that the immune system of SPF mice more closely resembles newborn human immunity, whereas immune systems from mice exposed to diverse pathogens more closely reflect adult human immunity.

To study the impact of microbial experience on the immune response, we have adopted a …

Barriers And Facilitators To Voting For People With Disabilities In Michigan Rural Communities, Christian Aguilar-Quiroz, Kaylyn Brzys, Chris Paclibar, Kyle Witte

Community Based

Objective: In this study, we sought to investigate and obtain data on the perceived barriers and facilitators that rural Michigan residents with disabilities face throughout the voting process.

Method: We conducted two separate focus groups in two different rural areas of Michigan asking a series of semi-structured questions about the participants’ voting experiences. We obtained recorded interviews, qualitative data, of their answers to these prepared questions.

Results: Physical accessibility was limited by poor lighting for people with low vision problems and a lack of accommodations for those who are not able to stand for a prolonged time while waiting in …

The Perceived Effects Of Occupational Therapy Interventions For Those Who Recently Transitioned From Homelessness To Permanent Housing, Sydney Krol, Madison Muir, Katie Johnson, Kristin Hazlett, Kaelyn Hughs

Community Based

OBJECTIVE. The study's objective was to examine the perceived effects of occupational therapy services for families who have recently transitioned to permanent housing from a period of homelessness.

METHOD. The study used a qualitative research design. One family received occupational therapy interventions administered by occupational therapy student researchers. Exit interview was audio recorded and transcribed.Themes and codes were derived from the transcription.

RESULTS. Three themes and seven codes were identified, which encompassed the participants perception of the intervention. The themes were lifestyle transformation, mindset development, and client centered care. The codes were organization and planning, roles and routines, goal progression, …

Occupation-Based Learning Modules In Preparation For Parole: A Program Evaluation, Alisha Cheyne, Gabrielle Martino, Elizabeth Vander Wall, Natalie Wallace

Community Based

A qualitative research study was conducted that examined occupational therapy students’ fieldwork rotation at Muskegon Correctional Facility, where they implemented a 15-week pre-parole program. One focus group with three participants was conducted. Transcription, coding, and theming followed, providing five themes; restriction, OT perceptions, learning styles, future needs, and relationships. Results showed areas of needs within this population, ways occupational therapy can address this need, and general improvements that can be made to pre-release programs.

Exploratory Study Of Children With Sensory Processing Disorder (Spd) Without An Autism Spectrum Disorder (Asd) Diagnosis, Breanna Williams, Lauren Brown, Kendall Grzywa, Emma Green

Pediatrics

The purpose of this study was to explore the prevalence of children with sensory processing disorder (SPD) without an autism spectrum disorder (ASD) diagnosis. Examples of these diagnoses include attention deficit hyperactivity disorder (ADHD), cerebral palsy (CP), posttraumatic stress disorder (PTSD), Oppositional Defiant Disorder (ODD), and Reactive Attachment Disorder (RAD). This was an exploratory descriptive study that gathered quantitative data through the Sensory Processing Measure (SPM) Home Form. The SPM Home Form was provided by occupational therapy (OT) students and completed by the child’s caregiver. The scores fell into three interpretive ranges: Typical, Some Problems, and Definite Dysfunction. Researchers hypothesized …

Caregiver Perspective On Sensory Diet And Therapeutic Listening For Children With Autism Spectrum Disorder And/Or Sensory Processing Disorder, Mikayla M. Brett, Lynette Zulquairnain, Katlyn Ribant

Pediatrics

Due to the high prevalence of Autism Spectrum Disorder (ASD) and Sensory Processing Disorder (SPD), there is a high demand for more research on effective interventions in order to improve quality of life and engagement in meaningful occupations for individuals with ASD and/or SPD. Sensory Diet (SD) and Therapeutic Listening © (TL) are interventions commonly utilized with individuals with ASD and/or SPD, however, there is limited research on their combined use. The purpose of this study is to determine the effectiveness of the combined occupational therapy (OT) interventions of SD and TL on the occupational performance of children with ASD …

Palbociclib Treatment Alters Nucleotide Biosynthesis And Glutamine Dependency In A549 Cells, Lindsey R. Conroy, Pawel Lorkiewicz, Liqing He, Xinmin Yin, Xiang Zhang, Shesh N. Rai, Brian F. Clem

Neuroscience Faculty Publications

Background

Aberrant activity of cell cycle proteins is one of the key somatic events in non-small cell lung cancer (NSCLC) pathogenesis. In most NSCLC cases, the retinoblastoma protein tumor suppressor (RB) becomes inactivated via constitutive phosphorylation by cyclin dependent kinase (CDK) 4/6, leading to uncontrolled cell proliferation. Palbociclib, a small molecule inhibitor of CDK4/6, has shown anti-tumor activity in vitro and in vivo, with recent studies demonstrating a functional role for palbociclib in reprogramming cellular metabolism. While palbociclib has shown efficacy in preclinical models of NSCLC, the metabolic consequences of CDK4/6 inhibition in this context are largely unknown.

Methods

In …

Thrower's Exostosis Of The Shoulder: A Systematic Review With A Novel Classification, Michael T. Freehill, Sandeep Mannava, Laurence D. Higgins, Alexandre Lädermann, Austin V. Stone

Orthopaedic Surgery and Sports Medicine Faculty Publications

Background: A variety of thrower's exostoses are grouped under the term Bennett lesion, which makes understanding diagnosis and treatment difficult.

Purpose: To identify all types of reported thrower's and overhead athlete's exostoses and categorize them into a classification system to allow a morphology-based classification.

Study Design: Systematic review; Level of evidence, 4.

Methods: A systematic review of all articles pertaining to Bennett lesions and thrower's exostosis was performed. The classification and treatments were evaluated to describe the types, proposed causes, diagnosis, and treatment options.

Results: A total of 27 studies were included in the systematic review. The anatomic locations …

Cad/Cam Milling Versus Rapid Prototyping Surgical Guide Techniques In Dental Implant Placement, Fardos N. Rizk Prof., Marwa Sabet Prof., Hebatallah Mohammed, Adham Elghamry

Dentistry

No abstract provided.

Predictors Of Biologic Use And Satisfaction Among Patients With Psoriasis: An Analysis And Geographic Visualization Of The 2016 And 2017 National Psoriasis Foundation Annual Surveys, Clinton W. Enos, Hadiza I. Galadima, Arjun Saini, Stacie Bell, Michael Siegel, Abby S. Van Voorhees

Community & Environmental Health Faculty Publications

Background: There are an increasing number of biologic therapies approved for the treatment of psoriasis. Previous reports have identified undertreatment as a concern in the United States. Undertreatment has been associated with decreased patient satisfaction and increased morbidity.

Objectives: Assess biologic use and satisfaction among respondents to the 2016 and 2017 National Psoriasis Foundation (NPF) Annual Surveys.

Methods: Retrospective data analysis of the 2016 and 2017 NPF Annual Survey responses from individuals with psoriasis. ArcGIS Pro software was utilized to generate maps and perform an optimized hot spot analysis of moderate-to-severe psoriasis and biologic use.

Results: …

Llusd Articulator - Volume 31, Number 1, Loma Linda University School Of Dentistry

Articulator (Dentistry)

Contents:

6 | Dean's Message
10 | Curriculum transformation continues
11 | Holli Riter appointed Chief Medical Officer
15 | Patient Layla's "jaw in a day"
17 | Just-in-time Homecoming 2020
26 | From the Class of 1970, a story of service
27 | LLUSD manages a pandemic
33 | Imaging Clinic acquires NewTom VGi EVO
35 | Lane Thomsen honored for CE contributions

A Rare Case Of Three Years Disease Free Survival In A Locally Advanced Parathyroid Carcinoma Successfully Excised By Complete Surgical Resection, Abdul Ahad Sohail, Bushra Ayub, Syed Akbar Abbas, Shafqat Ali Sheikh, Talha Ahmed Qureshi, Muhammad Usman Tariq, Asad Diwan

Department of Surgery Docs

Parathyroid carcinoma (PC) is one of the rarest malignancies making approximately 0.005% of all cancers. It may arise sporadically or less commonly, in conjunction with genetic endocrine syndromes. Due to the rarity of the disease, no general consensus or definitive guidelines exist for its pre-operative diagnosis, management, or follow up. Surgical tumor removal is the gold standard treatment to prevent its recurrence. Parathyroid carcinoma has a high recurrence rate ranging from 40 to 60% in recent literature. We report a case of a seventy-year-old elderly female with locally advanced parathyroid carcinoma successfully surgically excised completely with a 3 year disease …

Outbreak Of Novel Coronavirus (2019-Ncov): The First Three-Month Experience Of Anesthesiologists In Thai University Hospital, Benjamas Kiatkasemsan, Mutita Chaichalothorn, Titipon Payongsri, Somrat Charuluxananan

Chulalongkorn Medical Journal

No abstract provided.

Preventing Transmission Of Covid-19 Infections And Themental Health Sequalae Among Older People, Teo Shyh Poh

Chulalongkorn Medical Journal

No abstract provided.

Staphylococcus Aureus Carriage And Contamination Of Mobile Phones Among Students Of An-Najah National University In Palestine, Motasem Yosof Al-Masri, Nael Sodki Abu-Hasan

Chulalongkorn Medical Journal

No abstract provided.

Economic Benefits Of Medication Reconciliation Performed By Pharmacists In Heart Failure Clinic, Tasigan Chaemchoi, Adisak Weerasaksanti, Thanaporn Poohirunkul, Suthida Chanchencho, Yotsaya Kunlamas, Pitchapong Kositchaiwat, Sarawut Siwamogsatham, Angkawipa Trongtorsak, Sarinya Puwanant, Puwanant Sinphurmsukskul

Chulalongkorn Medical Journal

No abstract provided.

Bioceramic Resonance Induced Extrasensory Perception Or Altered State Of Consciousness: A Pilot Study Of Taiwan, Ting Kai Leung

Chulalongkorn Medical Journal

No abstract provided.

Effect Of A Family Member Support Program On Exercise Behavior Among Family Members With Hypertensive Patients, Warangkana Sonjai, Yupa Jewpattanakul, Rukchanok Koshakri

Chulalongkorn Medical Journal

No abstract provided.

Outcomes Of Hyperbaric Oxygen Therapy For Central Retinal Artery Occlusion In Somdech Phra Pinklao Hospital, Chatchadaporn Kraisornpornsan, Thosporn Vimolkej, Napang Kedkovid

Chulalongkorn Medical Journal

No abstract provided.

Impact Of A Multimodal Intervention Program On Hand Hygiene Compliance At Bangkok Tertiary Care Hospital, Wipaporn Natalie Songtaweesin, Suvaporn Anugulruengkit, Rujipat Samransamruajkit, Darintr Sosothikul, Mayuree Prinyawat, Ornanong Tangsrijitdee, Anry Nakphunsung, Patchareeyawan Srimuan, Jiratchaya Sophonphan, Chitsanu Pancharoen

Chulalongkorn Medical Journal

No abstract provided.

Mechanism Of Muscle Injury From Eccentric Exercise Induced Free Radicals And Protection With Antioxidants, Kultida Klarod, Pornprom Surakul

Chulalongkorn Medical Journal

No abstract provided.

Tea Polyphenols Extracted From Fresh Young Tea Leaves Exhibits Antibacterial Activity Against Some Bacterial Species: An In Vitro Study, Belal Hossain Sikder, Shafiul Alam, Shakir Moazzem, Hazrat Ali, Abdullah Al-Mamun, Shah Samiur Rashid

Chulalongkorn Medical Journal

No abstract provided.

Effect Of Social Skills Training Program On Social Functioning In Patients With Major Depressive Disorder In Outpatient Psychiatric Department, King Chulalongkorn Memorial Hospital, Vanussanun Jannim, Peeraphon Lueboonthavatchai

Chulalongkorn Medical Journal

No abstract provided.

Phosphodiesterase Isoforms And Camp Compartments In The Development Of New Therapies For Obstructive Pulmonary Diseases, Martina Schmidt, Isabella Cattani-Cavalieri, Francisco J. Nuñez, Rennolds S. Ostrom

Pharmacy Faculty Articles and Research

The second messenger molecule 3′5′-cyclic adenosine monophosphate (cAMP) imparts several beneficial effects in lung diseases such as asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). While cAMP is bronchodilatory in asthma and COPD, it also displays anti-fibrotic properties that limit fibrosis. Phosphodiesterases (PDEs) metabolize cAMP and thus regulate cAMP signaling. While some existing therapies inhibit PDEs, there are only broad family specific inhibitors. The understanding of cAMP signaling compartments, some centered around lipid rafts/caveolae, has led to interest in defining how specific PDE isoforms maintain these signaling microdomains. The possible altered expression of PDEs, and thus abnormal …