Medicine and Health Sciences Commons^™

Psychedelics: A Window To Mental Illness; Psilocybin And Depression, Kiomary Rivera Quintana

College of Pharmacy Student Research

No abstract provided.

Covid-19 Surveillance Testing Of Healthcare Personnel Drives Universal Masking Practice, Paul S. Schulz, Ashley M. Wilde, Steve T. Hester, Jim Frazier, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

Health care professionals (HCP) are at increased risk of COVID-19 infection due to the unpredictable clinical presentation of COVID-19 disease, limited SARS-CoV-2 testing, personal protective equipment (PPE) shortages, and the inherent inability to distance from patients. Infected HCP may infect others, including coworkers, leading to a simultaneous increase in the number of infections and decrease in the availability of HCP in a community. Due to PPE shortages, many healthcare systems have faced difficult decisions regarding utilization of PPE to protect HCP, patients, and the communities they serve. We describe Norton Healthcare’s success utilizing surveillance COVID-19 testing of HCP to inform …

Why Every Hospital Needs A Covid-19 Clinical Case Review Team, Ashley M. Wilde, Paul Schulz, Brian C. Bohn, Sarah E. Moore, Matthew Song, Clayton J. Patross, Bryan Denham, Jim Frazier, Steve T. Hester, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

A hospital’s response to a global pandemic requires a coordinated effort to provide consistent guidance as information rapidly changes. In the early months of the COVID-19 pandemic, diagnosis and subsequent containment was challenging due to unfamiliarity with disease presentation, unknown reverse transcription-polymerase chain reaction sensitivity, and inconsistent access to testing supplies. A centralized COVID-19 clinical case review team can provide guidance on test interpretation, isolation, resource coordination and more.

The Nurse Practitioner In The Time Of Covid, Julie Marfell, Lynn Kelso

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Letter From The Editors, Administrative Issues Journal Editors

Administrative Issues Journal

No abstract provided.

A Deductive, Participative, And Iterative Process: A Case Study In Curricular Review, Elizabeth Rozell, Jenifer Roberts, Cathy Starr, Sandy Bailey

Administrative Issues Journal

This paper focuses on a deductive, participative, and iterative process for curricular revision at a public Midwestern university in the Merchandising and Fashion Design program. A systematic, nonlinear, organized process is presented and details specific components used in curricular review. The guiding framework for the redesign was that of Garner and Buckley (1988). That is, feedback was solicited and incorporated from educators, students, and employers. In each of the two-year process, the program was viewed as a whole, with input from faculty at every step, and also viewed from a micro-perspective by examining each course individually. The process included peer …

Mastering Critical Thinking Competencies In Online Graduate Classes, Douglas Hermond, Tyrone Tanner

Administrative Issues Journal

Many colleges of education have embraced online course delivery as an expeditious means of delivering graduate programs. It behooves us to ensure that this delivery method does not compromise our ability to provide these students with necessary critical thinking competencies. This research was designed to determine the degree to which participants in online graduate courses value critical thinking and the degree to which they developed these skills. The results indicated that students both valued understanding, judgment, caution/skepticism, originality, and reflection/action, and developed them in their online classes. The implications confirm that online platforms allow for the development of critical thinking …

Gender Difference In Stem Career Aspiration And Social-Cognitive Factors In Collectivist And Individualist Cultures, Wei-Cheng Mau, Shr-Jya Chen, Jiaqi Li, Emily Johnson

Administrative Issues Journal

Gender equity in STEM demands that girls and women are provided with learning experiences, opportunities, and resources that meet their educational and vocational goals. This study examined gender difference in STEM learning experience, parental involvement, and self-efficacy to predict STEM career aspiration of different sociocultural groups. Two independent samples of high school students, one recruited from a collectivist culture (Taiwanese sample, N = 590) and the other recruited randomly from an individualist culture (American sample, N = 590), were used to examine the differences. Findings suggested a greater gender difference in STEM learning experience, parental involvement, and STEM self-efficacy of …

Protect Students’ Educational Futures Through Social Capital Opportunities In Sport And Non - Sport Extracurricular Activities, Roxanne Long

Administrative Issues Journal

his study provides empirical support that extracurricular participation correlates positively and significantly to future education, both directly and indirectly. However, which type of extracurriculars are best for students in their pursuit of higher education, sport or non - sport activities? Rooted in Social Capital Theory, the present study focuses on which type of participation provides the best capacity to acquire social capital that correlates to gains in higher education. Structural equation modeling was used with a representative, longitudinal sample of 5,239 ninth through twelfth graders. Total effects reveal that mixed participation (at least one sport and one non - sport …

An Overview Of Current Clinical Trials Of Agents For The Treatment And Prevention Of Covid-19 In The United States, Kenneth Schot Hannan, William P. Mckinney

The University of Louisville Journal of Respiratory Infections

Introduction: Given the rapid worldwide spread of SARS-CoV-2 and the attendant risks for severe complications and mortality, numerous clinical trials for its treatment and prevention have been generated in a short period. This report focuses on the categories of the wide spectrum of agents being studied in the United States and the intensity of effort involved with each so that clinicians may consider whether suggesting enrollment may be appropriate for their patients.

Methods: A search was completed of the ClinicalTrials.gov database on May 28, 2020, for all such trials underway as of that date in the US. A total 190 …

2020-07-22_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of care (POC) tests, look for current infection. Serology (antibody) tests are used to look for the possibility of previous infection.
Source: Michigan Disease Surveillance System (MDSS) and Vital Records

The website contained the tables …

2020-07-22_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

Noodles Made From High Amylose Wheat Flour Attenuate Postprandial Glycaemia In Healthy Adults, Kim Ang, Carla Bourgy, Haelee Fenton, Ahmed Regina, Marcus Newberry, Dean A. Diepeveen, Domenico Lafiandra, Sara Grafenauer, Wendy Hunt, Vicky Solah

Grain and Other Field Crops Research Articles

Previous research has not considered the effect of high amylose wheat noodles on postprandial glycaemia. The aim of the study is to investigate the effect of consumption of high amylose noodles on postprandial glycaemia over 2-h periods by monitoring changes in blood glucose concentration and calculating the total area under the blood glucose concentration curve. Twelve healthy young adults were recruited to a repeated measure randomised, single-blinded crossover trial to compare the effect of consuming noodles (180 g) containing 15%, 20% and 45% amylose on postprandial glycaemia. Fasting blood glucose concentrations were taken via finger-prick blood samples. Postprandial blood glucose …

2020-07-22_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-07-22_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data is updated on an ongoing basis.

The data below represents a cumulative total of confirmed COVID-19 resident cases, cumulative total of suspected and confirmed resident deaths, cumulative total of confirmed COVID-19 staff cases, and cumulative total of suspected and confirmed staff deaths reported by SNFs in Michigan since January 1, 2020. Case numbers are provisional and may change as facilities correct …

Recurring Pleural Effusion Secondary To Walled-Off Pancreatic Necrosis, Adwait Mehta, Gabriel Aisenberg, Roy Tomas Davee, Eden Henry, Nicole Thomason

Faculty, Staff and Student Publications

Recurring, exudative, lymphocytic-predominant pleural effusions have not been previously reported in association with walled-off pancreatic necrosis. We present a case of chronic pancreatitis complicated by a large pancreatic fluid collection and recurrent pleural effusion. Endoscopic drainage of the walled-off pancreatic necrosis was the definitive treatment for both fluid collections.

Assessing College Students’ Perceived Risk For Developing Type 2 Diabetes Mellitus, Carletta Weatherspoon

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

This study assesses the effectiveness of an evidence-based educational intervention affecting the perception of the risk for developing type 2 diabetes (T2DM) in college students and examined relationships between demographic factors and perception of risk for T2DM. Seventy-seven students from the Georgia College Association of Nursing Students (GCANS) and the Personal Health and Fitness Class participated. Of these, 43 participants completed the post-educational email survey. Instruments measured demographic characteristics, perception of risk for developing diabetes, and diabetes risk. The Risk Perception Survey for Developing Diabetes (RPS-DD) assessed students’ perception of risk at baseline and one week post intervention. There was …

Photovoice And Youth On Violence And Related Topics: A Systematic Review, Yingwei Yang, Andrew C. Lim, Renée E. Wallace, Stephanie Marhefka-Day, Karen D. Liller

Florida Public Health Review

Background and Purpose: Photovoice is a qualitative method that empowers youth to identify community issues and assets through photo-taking and photo discussions. The purpose of this systematic review was to explore the characteristics of studies using photovoice in violence and related topics among youth, and the rationale, strengths and limitations of the photovoice methodology when applied to youth.

Methods: Inclusion criteria, search strategy, and data extraction and analysis plan were specified in advance and documented in a protocol (Registration: PROSPERO-CRD42018087290). The search strategy included three search concepts: photovoice, youth, and violence-related topics. Two rounds of formal searches were executed across …

A Race Against Time: Reduced Azithromycin Susceptibility In Salmonella Enterica Serovar Typhi In Pakistan, Junaid Iqbal, Irum Fatima Dehraj, Megan E. Carey, Zoe A. Dyson, Denise Garrett, Jessica C. Seidman, Furqan Kabir, Senjuti Saha, Stephen Baker, Farah Naz Qamar

Department of Paediatrics and Child Health

Antimicrobial resistance is an ongoing issue in the treatment of typhoid fever. Resistance to first-line antimicrobials and extensively drug resistant (XDR) Salmonella Typhi isolates in Pakistan have left azithromycin as the only remaining effective oral treatment. Here, we report the emergence of organisms with a single point mutation in acrB gene, implicated in azithromycin resistance, in a S. Typhi isolate from Pakistan. The isolation of this organism is worrisome and highlights the significance of the introduction of typhoid conjugate vaccine in South Asia.
Importance: The emergence of XDR Salmonella Typhi in Pakistan has left azithromycin as the only viable oral …

Wild Mice With Different Social Network Sizes Vary In Brain Gene Expression, Patricia C. Lopes, Barbara König

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Background

Appropriate social interactions influence animal fitness by impacting several processes, such as mating, territory defense, and offspring care. Many studies shedding light on the neurobiological underpinnings of social behavior have focused on nonapeptides (vasopressin, oxytocin, and homologues) and on sexual or parent-offspring interactions. Furthermore, animals have been studied under artificial laboratory conditions, where the consequences of behavioral responses may not be as critical as when expressed under natural environments, therefore obscuring certain physiological responses. We used automated recording of social interactions of wild house mice outside of the breeding season to detect individuals at both tails of a distribution …

Regional And Experiential Differences In Surgeon Preference For The Treatment Of Cervical Facet Injuries: A Case Study Survey With The Ao Spine Cervical Classification Validation Group, Jose A Canseco, Gregory D Schroeder, Parthik D Patel, Giovanni Grasso, Michael Chang, Frank Kandziora, Emiliano N Vialle, F Cumhur Oner, Klaus J Schnake, Marcel F Dvorak, Jens R Chapman, Lorin M Benneker, Shanmuganathan Rajasekaran, Christopher K Kepler, Alexander R Vaccaro

Department of Neurosurgery Faculty Papers

PURPOSE: The management of cervical facet dislocation injuries remains controversial. The main purpose of this investigation was to identify whether a surgeon's geographic location or years in practice influences their preferred management of traumatic cervical facet dislocation injuries.

METHODS: A survey was sent to 272 AO Spine members across all geographic regions and with a variety of practice experience. The survey included clinical case scenarios of cervical facet dislocation injuries and asked responders to select preferences among various diagnostic and management options.

RESULTS: A total of 189 complete responses were received. Over 50% of responding surgeons in each region elected …

Identifying Pleiotropic Snps Associated With Femoral Neck And Heel Bone Mineral Density, Pei He, Xinag-He Ming, Xiao Zhang, Xu Lin, Qiang Zhang, Ri-Li Jiang, Martin R. Schiller, Fei-Yan Deng, Hong-Wen Deng

Life Sciences Faculty Research

Background: Genome-wide association studies (GWASs) routinely identify loci associated with risk factors for osteoporosis. However, GWASs with relatively small sample sizes still lack sufficient power to ascertain the majority of genetic variants with small to modest effect size, which may together truly influence the phenotype. The loci identified only account for a small percentage of the heritability of osteoporosis. This study aims to identify novel genetic loci associated with DXA-derived femoral neck (FNK) bone mineral density (BMD) and quantitative ultrasound of the heel calcaneus estimated BMD (eBMD), and to detect shared/causal variants for the two traits, to assess whether the …

Introduction Of An Advanced Practice Nurse Program In Kenya: A New Era In Nursing Education, Sheila Shaibu, Eunice Ndirangu, Eunice Pallangyo, Gladys Mbuthia, Rachel Kimani, Isabel Kambo

School of Nursing & Midwifery, East Africa

Purpose: The purpose of this presentation is to share the intra and interprofessional collaborative process of developing an Advanced Practice Nursing (APN) program to be offered in 2020 in Kenya, a low middle-income country.

Methods: Engagement with stakeholders (students, clinicians, regulators and educators) affirmed the need for an APN program. Faculty from Schools of Nursing and Midwifery in three East African countries developed an APN curriculum with input from local and international agencies such as the Nursing Council of Kenya with linkages to the ICN, the Nursing Now Team and partner universities in the UK and USA. The …

Rna-Gps Predicts Sars-Cov-2 Rna Residency To Host Mitochondria And Nucleolus, Kevin E Wu, Furqan M Fazal, Kevin R Parker, James Zou, Howard Y Chang

Faculty, Staff and Students Publications

SARS-CoV-2 genomic and subgenomic RNA (sgRNA) transcripts hijack the host cell's machinery. Subcellular localization of its viral RNA could, thus, play important roles in viral replication and host antiviral immune response. We perform computational modeling of SARS-CoV-2 viral RNA subcellular residency across eight subcellular neighborhoods. We compare hundreds of SARS-CoV-2 genomes with the human transcriptome and other coronaviruses. We predict the SARS-CoV-2 RNA genome and sgRNAs to be enriched toward the host mitochondrial matrix and nucleolus, and that the 5' and 3' viral untranslated regions contain the strongest, most distinct localization signals. We interpret the mitochondrial residency signal as an …

Atrial High-Rate Episodes, Subclinical Atrial Fibrillation And Short-Duration Clinical Atrial Fibrillation: Different Names For The Same Arrhythmia Or A New Player On The Pitch?, Juan Benezet-Mazuecos, Alvaro Lozano Rosado, Julian Crosa, Jose Antonio Iglesias

Journal of the Saudi Heart Association

No abstract provided.

Infected Coronary Artery Aneurysm - A Rare But Fatal Complication Of Percutaneous Coronary Intervention, Ajit Pal Singh, Harnoor Singh Pruthi

Journal of the Saudi Heart Association

A 43 year old male underwent successful Percutaneous Coronary Intervention (PCI) to LCX. 3 months after the procedure, he presented with NYHA class III-IV angina associated with low grade fever and reduced appetite. Biochemical parameters including complete blood count and renal function tests were normal. ECG showed ST segment depression in lateral leads. Echocardiography showed lateral wall hypokinesia with moderate Mitral valve regurgitation. Coronary angiogram revealed large mycotic aneurysms in LAD and LCX coronary arteries (Image 1). Blood culture showed growth of Pseudomonas aeruginosa. Infected coronary aneurysms are a rare and potentially fatal complication after drug eluting stent implantationand …

Physical Activity Interventions For Older Adults: Efficacy, Adherence And Sustainability For Stroke Prevention Outcomes, Agnieszka Suminski

DePaul Discoveries

Objective: To examine outcomes of older adults who participate in physical activity intervention programs, whether there is a significant difference in group and individual based physical activity interventions, and assess promise of older adult behavior change post-intervention. Methods: Literature review using seventeen previously published data on physical activity intervention programs for older adults. Results: Studies suggest that physical activity program intervention for older adults show improved physical and mental outcomes. Group-based interventions are more successful for program adherence. Discussion: Family and social support play a significant role in participant adherence to program physical adherence interventions, as well as sustained …

Association Of Neighborhood Disorder And Minority Stress With Depression Among Young Gay And Bisexual Males In Denver And Chicago, Liesl Gonzales, Douglas Bruce

DePaul Discoveries

Excess risk for poor mental health outcomes has been found within sexual minority populations. This study aimed to examine factors that may contribute to depression rates within two populations of YMSM in Denver and Chicago. 100 HIV-positive and 100 HIV-negative YMSM completed a survey regarding demographic information, minority stress (such as same-sex stigma), and perceived neighborhood disorder. Chicago participants reported higher rates of neighborhood disorder, history of incarceration, and being kicked out of a parent’s house, variables predicted to be positively correlated with depression. Surprisingly, it was found that YMSM in Denver were significantly more likely to have depressive symptoms …

Examination Of Inflammatory Caspase Aggregates Formed In The Presence Of Lipopolysaccharide, Grant D. Andersen

DePaul Discoveries

Inflammatory caspases are involved in the innate immune response, in which cell damage and microorganism invasion lead to cell death via pyroptosis and the release of chemical signals that produce inflammation. Currently, little is known pertaining to the mechanism of activation for one of the major caspase isoforms, caspase-4, other than its ability to bind LPS and become more active because of it. It has been theorized that caspase-4 agregation occurs through a non-cannonical based pathways in forming its respective complex following binding to LPS. Alternatively, caspase-4 may be activated after binding LPS micelles. Herein, we sought to incorporate lipopollysaccharide …

Depaul Discoveries Volume 9 Cover, Steven Reese

DePaul Discoveries

No abstract provided.