Medicine and Health Sciences Commons^™

Outlaw Operators: Prevention Failures And The Resurgence Of Black Lung In Central Appalachia, Aysha Bodenhamer

Carsey Publications

In this brief, author Aysha Bodenhamer describes how prevention failures in the coal mining industry have resulted in the resurgence of black lung disease. Caused by the chronic inhalation of coal and silica dust, black lung is progressive, incurable, life-altering, and fatal. Despite it being a preventable disease, black lung is resurgent among coal miners in Kentucky, Virginia, and West Virginia. Fieldwork including in-depth interviews with miners, clinic workers, black lung attorneys, government employees, and lay advocates, and a case-study analysis of two black lung clinics in southwest Virginia inform this analysis. These data reveal that coal operators routinely evade …

Screening Tests For Active Pulmonary Tuberculosis In Children, Bryan Vonasek, Tara Ness, Yemisi Takwoingi, Alexander W. Kay, Susanna S. Van Wyk, Lara Ouellette, Ben J. Marais, Karen R. Steingart, Anna M. Mandalakas

Library Staff Publications

Background: Globally, children under 15 years represent approximately 12% of new tuberculosis cases, but 16% of the estimated 1.4 million deaths. This higher share of mortality highlights the urgent need to develop strategies to improve case detection in this age group and identify children without tuberculosis disease who should be considered for tuberculosis preventive treatment. One such strategy is systematic screening for tuberculosis in high-risk groups.

Objectives: To estimate the sensitivity and specificity of the presence of one or more tuberculosis symptoms, or symptom combinations; chest radiography (CXR); Xpert MTB/RIF; Xpert Ultra; and combinations of these as screening tests for …

2020-07-28_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Community-Level Interventions For Pre-Eclampsia (Clip) In Pakistan: A Cluster Randomised Controlled Trial, Rahat Qureshi, Sana Sheikh, Zahra Hoodbhoy, Sumedha Sharma, Marianne Vidler, Beth A. Payne, Imran Ahmed, J Mark Ansermino, Jeffrey Bone, Zulfiqar Ahmed Bhutta

Woman and Child Health

Objectives: To reduce all-cause maternal and perinatal mortality and major morbidity through Lady Health Worker (LHW)-facilitated community engagement and early diagnosis, stabilization and referral of women with preeclampsia, an important contributor to adverse maternal and perinatal outcomes given delays in early detection and initial management.
Study design: In the Pakistan Community-Level Interventions for Pre-eclampsia (CLIP) cluster randomized controlled trial (NCT01911494), LHWs engaged the community, recruited pregnant women from 20 union councils (clusters), undertook mobile health-guided clinical assessment for preeclampsia, and referral to facilities after stabilization.
Main outcome measures: The primary outcome was a composite of maternal, fetal and …

Interactions Between The Physical And Social Environments With Adverse Pregnancy Events Related To Placental Disorders—A Scoping Review, Yolisa Prudence Dube, Newton Nyapwere, Laura A. Magee, Marianne Vidler, Sophie E. Moore, Benjamin Barratt, Rachel Craik, Peter Von Dadelszen, Prestige Tatenda Makanga, Marleen Temmerman, Angela Koech, Patricia Okiro, Geoffrey Omuse, Sikolia Wanyonyi

Obstetrics and Gynaecology, East Africa

Background: Due to different social and physical environments across Africa, understanding how these environments differ in interacting with placental disorders will play an important role in developing effective interventions.

Methods: A scoping review was conducted, to identify current knowledge on interactions between the physical and social environment and the incidence of placental disease in Africa.

Results: Heavy metals were said to be harmful when environmental concentrations are beyond critical limits. Education level, maternal age, attendance of antenatal care and parity were the most investigated social determinants.

Conclusions: More evidence is needed to determine the relationships between the environment and placental …

The Roles Of Grks In Hemostasis And Thrombosis, Xi Chen, Xuefei Zhao, Matthew Cooper, Peisong Ma

Department of Medicine Faculty Papers

Along with cancer, cardiovascular and cerebrovascular diseases remain by far the most common causes of death. Heart attacks and strokes are diseases in which platelets play a role, through activation on ruptured plaques and subsequent thrombus formation. Most platelet agonists activate platelets via G protein-coupled receptors (GPCRs), which make these receptors ideal targets for many antiplatelet drugs. However, little is known about the mechanisms that provide feedback regulation on GPCRs to limit platelet activation. Emerging evidence from our group and others strongly suggests that GPCR kinases (GRKs) are critical negative regulators during platelet activation and thrombus formation. In this review, …

Exploring Predictors Of Older Adults' Performance On A Novel Driving Simulator Task, John Philip Bernstein

LSU Doctoral Dissertations

On a per-mile driven basis, older adults are at increased risk of being involved in an automobile accident. The development and implementation of driving assessment tools is necessary to inform decisions about driving reduction and cessation. Driving simulators are one method of assessing driving performance and safety, however many simulators are cost-prohibitive for most researchers and clinicians. Additionally, while driving performance has been previously explored with respect to clinical populations (e.g., Alzheimer’s Disease), less work has evaluated this topic in a cognitively healthy sample. The present study sought to determine whether a novel, cost-effective driving simulator (Assetto Corsa (AC)) might …

High Flow Nasal Cannula In The Surgical Patient, Morta Lapkus, Paras Khandhar

Articles

No matter how much they want it, airway management and the decision to place a surgical patient on a ventilator should not just be for the PICU physicians to decide. The type of ventilation a patient receives can affect the surgical patient both positively and negatively. Could High Flow Nasal Cannula in the surgical patient be beneficial? Imagine a patient with an esophageal anastomosis that is extubated to CPAP. Now imagine the tears that would flow from the surgeon when they discover bilateral pneumothoraces and a blown-out anastomosis. Tragic. Therefore, we must weigh the risks and benefits of intubation versus …

Impact Of 12-Weeks Of Nordic Pole Walking On Arterial Stiffness In Sedentary Overweight And Obese Adults, Arbër N. Shehu

Masters Theses, 2020-current

Arterial stiffness (AS) is an independent predictor for cardiovascular disease morbidity and mortality. Regular aerobic exercise is considered to improve AS. Nordic walking provides important health benefits, however, the effect of this walking method as treatment for AS remains unclear. We conducted a randomized controlled study to examine the effect of a 12-week supervised group walking intervention (controlled pace, ~3000 steps/day, 30 minutes/day, 5 times/week), with (NW) and without (SW) Nordic poles, on AS in sedentary overweight and obese adults. Fourteen individuals were randomly assigned to NW (n=7; median age 54.0 years; body mass index (BMI)=31.3 kg/m²) or …

Graduate Commencement, Philadelphia (2020), Philadelphia College Of Osteopathic Medicine

Commencements

Philadelphia Campus Graduate Program Commencement program, Class of 2020. Degrees include Master of Science in Forensic Medicine, Master of Science in Biomedical Sciences. Master of Science in Health Sciences – Physician Assistant Studies, Master of Science in School Psychology, Master of Science in Counseling and Clinical Health Psychology, Master of Science in Mental Health Counseling, Master of Science in Organizational Development and Leadership, Master of Science in Public Health Management and Administration, Master of Science in Non Profit Leadership & Population Health Management, Educational Specialist in School Psychology, Doctor of Psychology in Clinical Psychology, and Doctor of Psychology in School …

The Surveillance For Enteric Fever In Asia Project (Seap), Severe Typhoid Fever Surveillance In Africa (Seta), Surveillance Of Enteric Fever In India (Sefi), And Strategic Typhoid Alliance Across Africa And Asia (Strataa) Population-Based Enteric Fever Studies: A Review Of Methodological Similarities And Differences, Megan E. Carey, William R. Macwrigh, Justin Im, James E. Meiring, Malick M. Gibani, Se Eun Park, Ashley Longley, Hyon Jin Jeon, Caitlin Hemlock, Mohammad Tahir Yousafzai, Farah Qamar

Department of Paediatrics and Child Health

Building on previous multicountry surveillance studies of typhoid and others salmonelloses such as the Diseases of the Most Impoverished program and the Typhoid Surveillance in Africa Project, several ongoing blood culture surveillance studies are generating important data about incidence, severity, transmission, and clinical features of invasive Salmonella infections in sub-Saharan Africa and South Asia. These studies are also characterizing drug resistance patterns in their respective study sites. Each study answers a different set of research questions and employs slightly different methodologies, and the geographies under surveillance differ in size, population density, physician practices, access to healthcare facilities, and access to …

Nonsurgical Correction Of Skeletal Class Iii Malocclusion With Evident Profile Change In An Adult Patient With Functional Shift And Low Mandibular Plane Angle, Ting-Yu Kuo, Chun-Liang Kuo

Taiwanese Journal of Orthodontics

This article reports the successfully utilize the range of functional shift to treat a 16-year-old female with a chief complaint of anterior crossbite. The patient had a skeletal Class III malocclusion with a protrusive mandible, anterior crossbite, low mandibular plane angle and facial asymmetry.

To achieve optimal correction of facial profile and occlusion, orthognathic surgery would be the first treatment option. However, this patient and her family declined the surgical option for higher cost. As a consequence, we use lower anterior bite turbo to disocclude posterior teeth for the posterior teeth extrusion. Class III elastics were applied for the correction …

Non-Surgical Treatment For A Patient With Condyle Head Resorption And Unstable Occlusion, Tsung-Jui Hsieh, Tzu-Ying Wu

Taiwanese Journal of Orthodontics

This case report presents multiple TADs application technique on managing difficult dental and skeletal malocclusion. This 36-year-old female who was diagnosed as rheumatoid arthritis and had been under medication control for 6 years. In addition, she was diagnosed as condyle erosion with bilateral crepitus sound during jaw movement. The characters of occlusion including Class II malocclusion with increased overjet (6 mm), multiple posterior teeth missing and super-erupted teeth 17 and 26, and unstable occlusion. During phase I, patient was referred for occlusal splint treatment, and we followed the progression of condylar condition. At phase II, surgical intervention was suggested but …

Non-Surgical And Non-Extraction Orthodontic Treatment Of An Excess Reverse Bite With Anterior Open Bite, Jung-Chi Hsu, I-Hua Liu, Chun-Liang Kuo, Chun-Hsiu Yang, Yu-Ling Tsai, Chung-Li Wang

Taiwanese Journal of Orthodontics

This 13-year-old female had a severe Angle’s Class III malocclusion with an excessive negative overjet 7 mm, anterior open bite 2 mm, a prognathic chin and a concave lateral profile. But this patient and her parents refused orthognathic surgery. Finally, she was treated with a non-surgical and non-extraction approach. The treatment plan consisted of total distalization of mandibular dentition with bilateral temporary anchorage device (TAD) and maxillary incisor extrusion with vertical elastics. The active treatment period was 34 months. Normal overbite, overjet, and acceptable profile were achieved.

Applications Of Artificial Intelligence In Orthodontics, Hsien-Ching Hung, Yi-Chin Wang, Yu-Chih Wang

Taiwanese Journal of Orthodontics

Artificial intelligence (AI) technology is a tool for finding insights in different kind of information in medical field. The purpose of this article was giving a brief introduction to applications of AI in orthodontic treatment. The reviewed literatures were further categorized into (1) extraction or non-extraction therapy in orthodontic treatment, (2) orthognathic surgery, (3) segmentation and landmark identification, (4) growth prediction, (5) cleft related studies, and (6) TMD classification.

Surgical Methods To Accelerate Tooth Movement, Miao-Jing Chen, Shih-Chieh Chen, Jung-Hsuan Cheng, Yu-Chuan Tseng Dds, Mds, Phd

Taiwanese Journal of Orthodontics

Comprehensive orthodontic treatment usually takes 1–3 years to finish the details. The treatment duration depends on the complexity of treatment. Longer treatment times may increase the risk of root resorption, oral hygiene–related problems such as white spot lesion or dental caries, and periodontal destruction. Several methods, such as surgical-assisted procedures, drugs, and physical/mechanical stimulation methods, may accelerate tooth movement and shortened whole treatment time. This article reviews various surgical-assisted procedures and how the surgical method that can effectively shorten the treatment time. The advantages and disadvantages of various technique were also assessed.

Treatment Efficacy Of Invisalign: Literature Review Update, Meng-Huan Tsai, Stephanie Shih-Hsuan Chen, Yi-Jane Chen, Jane Chung-Chen Yao

Taiwanese Journal of Orthodontics

Purpose: Inconsistency between computer prediction and actual tooth movement in Invisalign treatment always limits clinical judgment. The objective of this review was to update the evidence on the treatment efficacy of the Invisalign appliance.
Material and Methods: Medical databases were screened for relevant peer-reviewed articles from 2000 to 2018 for the use of Invisalign as a treatment intervention. All human studies other than case reports and case series were included.
Results: A total of 25 articles (4 RCTs, 6 prospective cohort studies, 15 retrospective cohort studies) were included. Treatment outcomes have been improving over the past 17 years. Invisalign treatment …

Impact Of Ramadan Fasting On Biochemical And Exercise Parameters Among Patients Undergoing Exercise-Based Cardiac Rehabilitation, Hazem Khorshid, Adel Shabana, Osama Rifaie, Yasser Abdellatif

Journal of the Saudi Heart Association

Background: Ramadan fasting is an important worship activity for Muslims. It is not known if fasting could have deleterious effect on cardiac patients joining cardiac rehabilitation (CR) program, especially during summer season.

Aim: To assess the effect of Ramadan fasting on biochemical and exercise parameters among patients undergoing 12- week exercise-based CR program. Patients and methods: 53 patients joining CR program in university hospital were included in the study. The patients were divided into two groups according to their Ramadan fasting status. Fasting group included 32 patients, while nonfasting group included 21 patients. All patients underwent supervised exercise-based CR during …

Percutaneous Coronary Interventions In Chronic Total Occlusion - Profile, Technique And Outcome -The Malabar Experience, Desabandhu Vinayakumar, Madhusudan Pramod Raikar, Kurukkanparampil Sreedharan Mohanan

Journal of the Saudi Heart Association

Introduction: Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) remains a challenge. The reasons being that these procedures may be lengthy and complex, with elevated radiation exposure, increased contrast load, lower procedural success rate, and a higher risk of complication when compared with non-CTO elective PCI. Clarifying the long-term clinical outcomes of CTO-PCI is very important to justify potential investments in training and technology. However, there is a paucity of data from Indian subcontinent. Hence we decided to report the outcomes from a real-life cohort of consecutive patients undergoing elective PCI for CTO at our institution.

Materials and methods: …

3d Bioprinting For Reconstituting The Cancer Microenvironment., Pallab Datta, Madhuri Dey, Zaman Ataie, Derya Unutmaz, Ibrahim T Ozbolat

Faculty Research 2020

The cancer microenvironment is known for its complexity, both in its content as well as its dynamic nature, which is difficult to study using two-dimensional (2D) cell culture models. Several advances in tissue engineering have allowed more physiologically relevant three-dimensional (3D) in vitro cancer models, such as spheroid cultures, biopolymer scaffolds, and cancer-on-a-chip devices. Although these models serve as powerful tools for dissecting the roles of various biochemical and biophysical cues in carcinoma initiation and progression, they lack the ability to control the organization of multiple cell types in a complex dynamic 3D architecture. By virtue of its ability to …

Severe Covid-19, Arpan H. Chawala, Shivam Gulati, Bettina Sinanova, Jose Bordon

The University of Louisville Journal of Respiratory Infections

Introduction: There is substantial variation in the clinical characteristics and outcomes of severe coronavirus disease (COVID-19), making it difficult to do an optimal assessment of this condition. We reviewed the current English literature to identify the findings concerning the baseline characteristics and health outcomes of patients with severe COVID-19, primarily those with acute respiratory distress syndrome (ARDS).

Methods: We examined only studies that assessed patients with confirmed COVID-19 by reverse transcription-polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) with at least one of the following severity criteria: treated in the intensive care unit (ICU), ARDS, and/or invasive …

Is Sars-Cov-2 A Neurotropic Virus And A Potential Facilitator Of Cns Infection For Other Pathogens?, Jose Bordon

The University of Louisville Journal of Respiratory Infections

No abstract provided.

2020-07-27_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of care (POC) tests, look for current infection. Serology (antibody) tests are used to look for the possibility of previous infection.
Source: Michigan Disease Surveillance System (MDSS) and Vital Records

The website contained the tables …

2020-07-27_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

Bayesian Model Selection Reveals Biological Origins Of Zero Inflation In Single-Cell Transcriptomics., Kwangbom Choi, Yang Chen, Daniel A Skelly, Gary A Churchill

Faculty Research 2020

BACKGROUND: Single-cell RNA sequencing is a powerful tool for characterizing cellular heterogeneity in gene expression. However, high variability and a large number of zero counts present challenges for analysis and interpretation. There is substantial controversy over the origins and proper treatment of zeros and no consensus on whether zero-inflated count distributions are necessary or even useful. While some studies assume the existence of zero inflation due to technical artifacts and attempt to impute the missing information, other recent studies argue that there is no zero inflation in scRNA-seq data.

RESULTS: We apply a Bayesian model selection approach to unambiguously demonstrate …

2020-07-27_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

2020-07-27 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Pediatric Bullying Education In Arkansas Baccalaureate Nursing Programs, Jasmine Jackson

McNair Scholars Research

Over the years, there has been an ever-increasing spotlight on the issue of bullying among adolescents. Nurses are another adult-figure, in addition to parents and teachers, that can help identify and address bullying if educated properly. The purpose of this study was to examine pediatric bullying education in Arkansas baccalaureate nursing programs. Through the use of a mixed-method approach, the newly created survey was to be completed by one faculty member from each of the 12 BSN programs in Arkansas (12 participants; 6 respondents). The paper describes the quantitative and qualitative data analysis from this non-experimental descriptive pilot study. Results …

2020-07-27_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data is updated on an ongoing basis.

The data below represents a cumulative total of confirmed COVID-19 resident cases, cumulative total of suspected and confirmed resident deaths, cumulative total of confirmed COVID-19 staff cases, and cumulative total of suspected and confirmed staff deaths reported by SNFs in Michigan since January 1, 2020. Case numbers are provisional and may change as facilities correct …

Développer Le Contenu D'Un Outil D'Aide À L'Amélioration Des Compétences Interculturelles Des Intervenants De La Cnesst À Partir D'Une Démarche De Coconstruction, Daniel Côté, Jessica Dubé, Nicolas Bastien, Sylvie Gravel

Rapports de recherche scientifique

Selon les intervenants de la Commission des normes, de l'équité, de la santé et de la sécurité du travail (CNESST), presque 50 % des travailleurs touchés par une lésion professionnelle sur l’île de Montréal seraient issus de l’immigration (ou de groupes ethnoculturels) (CNESST, 2010). Il ne s’agit que d’une estimation, puisque les indicateurs ethnoculturels tels que le pays de naissance, la langue maternelle ou autres ne sont pas des données colligées par la CNESST. Dans le cadre du projet de l’IRSST intitulé Comprendre le processus de réadaptation et de retour au travail dans le contexte des relations interculturelles (Côté et …