Medicine and Health Sciences Commons^™

Cell Cycle Regulation In Macrophages And Susceptibility To Hiv-1, Isabella A. T. M. Ferreira, James Zachary Porterfield, Ravindra K. Gupta, Petra Mlcochova

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Macrophages are the first line of defence against invading pathogens. They play a crucial role in immunity but also in regeneration and homeostasis. Their remarkable plasticity in their phenotypes and function provides them with the ability to quickly respond to environmental changes and infection. Recent work shows that macrophages undergo cell cycle transition from a G0/terminally differentiated state to a G1 state. This G0-to-G1 transition presents a window of opportunity for HIV-1 infection. Macrophages are an important target for HIV-1 but express high levels of the deoxynucleotide-triphosphate hydrolase SAMHD1, which restricts viral DNA synthesis by decreasing levels of dNTPs. While …

Mexico: Covid-19 Knowledge, Attitudes And Practices, Population Council

Poverty, Gender, and Youth

This brief presents responses from the first round of data collection among adults, adolescents, and community leaders in indigenous municipalities of Chiapas and Yucatan, Mexico, June 1–30, 2020. In total, 295 people from 17 municipalities were surveyed in Yucatan, and 83 people from 15 municipalities were surveyed in Chiapas. Adults and adolescents in both states identified the groups most at risk of suffering complications. Food insecurity may be a consequence of the pandemic. Regarding livelihoods, 51% of women and 63% of men in Yucatan have lost their work and/or their primary source of income since the start of the pandemic, …

Factors Influencing Choice Of Communication Sciences And Disorders Major For Students Who Are Culturally And Linguistically Diverse, Joanna Reinders

Dissertations, Theses, and Projects

The purpose of this study was to explore the motivating factors that influenced undergraduate students from culturally and linguistically diverse (CALD) backgrounds in the West North Central division of the United States to major in communication sciences and disorders (CSD). This was a nonexperimental study that was conducted by sending a quantitative survey on Qualtrics to undergraduate CSD students in schools in the West North Central division of the United States as defined by the U.S. Census (Census Regions and Divisions of the United States, n.d). All states had respondents to the survey except Nebraska and among the responses, 16 …

Effective Ultrasound And Neural Mobilization Combinations In Reducing Hand Disabilities In Carpal Tunnel Syndrome Patients, Ni Luh Nopi Andayani, Ari Wibawa, Made Hendra Satria Nugraha

Jurnal Keperawatan Indonesia

Excessive activity in the hands and wrists over a prolonged period of time can cause repetitive strain injury, which leads to the occurrence of carpal tunnel syndrome. The purpose of this study is to determine the differences in the effectiveness of ultrasound therapy and neural mobilization interventions with ultrasound therapy and passive stretching in reducing hand disabilities in patients with carpal tunnel syndrome. It is an experimental study, using the pre-and post-test control group design. The sampling technique employed was simple random sampling, with a study sample comprising 30 people.The difference test with an independent t-test showed a significant difference …

Pre-Testing Of The Who’S Educational Video: “How To Protect Yourself Against Covid-19”, Hilyatul Fadliyah, Manendra Muhtar, Munih Munih, Sylviasari Risgiantini, Weny Wulandary, Hadi Pratomo

Kesmas

The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was declared a public health emergency in many countries, including Indonesia. The World Health Organization (WHO) released an educational video, entitled "How to Protect Yourself Against COVID-19", which explained how to prevent the spread of COVID-19. This study is a qualitative study that aims to pre-test this video, based on the Information, Education, Communication (IEC) theory, by analyzing teenagers’ perceptions of the video. The design used was a Rapid Assessment Procedure (RAP), and the data were collected by conducting in-depth interviews with participants, through …

Impact Of Lockdown In India: A Case Study Comparing Kanataka With International Model, Stelvin Sebastian, Aby Paul, Jeeva Joseph, Joel Joby, Sanjo Saijan, Jobin Kunjumon Vilapurathu

Kesmas

The COVID-19 was declared a pandemic and a global health emergency by WHO, prompting various countries to implement early and stringent social distancing protocols through lockdown, to flatten the epidemic curve. The objective of the present study was to assess the impacts and effectiveness of the lockdown protocol in Karnataka and Punjab, compared with the implementation of this method in Australia and the UK. This study involved the collection of data from different authorized databases, in two phases. The first phase included the time starting with the first-reported index case through the 14th day after the declaration of lockdown, for …

Review Of Trial Therapies And Treatment For Covid-19: Lessons For Indonesia, Halma Zahro Mukhlida, Hilma Hasro Maulida, Gunanti Khairunnisa, Margaretha Josephine Mantrono, Risky Kusuma Hartono, Rindu Rindu, Eka R W Purnamasari, Rizky Fajar Meirawan

Kesmas

The infectious disease from Coronavirus Disease 2019, or COVID-19, has quickly spread world-wide since 2019. Therapies for managing COVID-19 have yet to be confirmed as medication for the severe sickness that the disease may cause. This study aimed to review the previous research of the efficacy of trial therapy and treatment to the patients in the hospital with COVID-19. Using PRISMA guidelines as a method for conducting a systematic literature review, a total of 67 articles were collected from several online journal databases. Various therapies were found that are effective in the treatment and management of COVID-19. In accordance with …

Working Beyond 80: The Meaning Of Work To An Octogenarian In The Workforce, Ma. Mayla Imelda M. Lapa, Laurence L. Gracia, Endrex P. Nemenzo

Jurnal Keperawatan Indonesia

There is an increasing share of people aged 50 years and over in the labor market structure and the rapid aging of the global workforce that supports the latter claim but with a little tank of information on qualitative research describing the experiences of a working octogenarian. An octogenarian is a person who is between 80 and 89 years old. This study aimed to investigate the experiences of a working octogenarian in her fieldwork through a qualitative case study analysis. From the interview, the following three themes were revealed: (a) Work as a legacy, (b) Work as an advocacy, and …

Empowering The Lowland Indigenous Community Through Child Health And Nutrition Program In Occidental Mindoro Province, Philippines, Artemio Morado Gonzales Jr

ASEAN Journal of Community Engagement

Nutrition and child health programs were integrated into the extension programs from 2016-2018 of the Occidental Mindoro State College, in partnership with the local government unit at the municipal and barangay levels. This paper presents the health extension tools and techniques used in preventative care and the promotion of child health services in the indigenous community of Sitio Bato Singit, in the Occidental Mindoro Province, Philippines. Health education, small group techniques, demonstrations, storytelling, informal talks, and open forums were the methods and techniques employed to implement the program. The common tools used were seating arrangements, flip-charting, props, social hours, and …

Analysis Of Knowledge Regarding Biliary Atresia Among Healthcare Providers And Laypersons In East Jakarta After Educational Intervention, Hanna Lianti, Novi Kurnia, Kshetra Rinaldhy, Amanda Safira Aji, M Febriadi Ismet, Rizky Amaliah

ASEAN Journal of Community Engagement

Biliary atresia (BA) is the most common cause of death due to liver disease in children and is the most common indication for pediatric liver transplantation. The success rate of the management of BA is very dependent on the age of the patient at the time of surgery. However, patients with BA were often diagnosed late because of the lack of parents’ and primary healthcare providers’ knowledge regarding BA. This study aims to evaluate the effectiveness of health education in improving the knowledge of healthcare providers and laypersons. A total of 371 respondents participated in this pre-post study with no …

Adaptation To Sexual Dysfunction In Patients With Chronic Renal Failure, Akhyarul Anam, Lestari Sukmarini, Agung Waluyo

Jurnal Keperawatan Indonesia

The prevalence of chronic renal failure in Indonesia tends to increase in the lower age group (45–54 years).Chronic renal failure may lead to impaired sexual function. A descriptive phenomenology study with in-depth interviews was carried out with 12 participants, and thematic content analysis was applied. Six themes were revealed, as follows: 1) adaptation process to sexual dysfunction experienced, 2) sexual dysfunction experience,3)importance of fulfilling sexuality needs,4) behavior in dealing with sexual dysfunction, 5) perception of the cause of sexual dysfunction, and 6) participants’ expectation of health service related to sexual function. The experience of adapting to sexual dysfunction became a …

Job Demands–Resources Model Affects The Performance Of Associate Nurses In Hospital, Khairunnisa Batubara, Bustami Syam, Sri Eka Wahyuni

Jurnal Keperawatan Indonesia

Low nurses’ performance is related with increased job demands and unprofessional job resources. This cross-sectional study aimed to analyze the effects of the job demands–resources model on the performance of associate nurses. The study population was composed of 126 nurses randomly selected. Data were analyzed using the multiple linear regression test. The results showed that job demands and job resources significantly affected the performance of associate nurses. A moderate or heavy level of job demands supported with good job resources will have a positive effect on nurse motivation; thus, nurse’s performance remains good. Job demands must be balanced with job …

Qualitative Approach To Understanding Barriers To Delivering Difficult News In Sub Saharan Africa, Karishma Sharma, Jasmit Shah, Sayed Karar

Internal Medicine, East Africa

Communication, especially delivery of difficult news (DDN), remains a key part of clinical practice. Despite its importance, many medical providers lack the skill and ability to effectively DDN to their patients. Due to lack of data specific to sub-Saharan Africa and to help us develop an appropriate training tool for this geographical area, we sought to explore what challenges and barriers residents at our institution faced when they deliver difficult news to their patients.

Tuberculosis Cases Finding Practice: The Intention Of Cadres, Agnes Pude Lepuen, Cicilia Nony Ayuningsih Bratajaya, Sada Rasmada

Jurnal Keperawatan Indonesia

Tuberculosis (TB) is a difficult health problem to overcome. Active case finding is an important step in managing this infectious disease. However, the prevalence of TB case finding among cadres at the community level is low because of the stigma attached to TB, difficulty in geographical coverage, low public awareness, and social economic barriers. In addition, the empowerment and intention of cadres to perform community-based TB case finding are not optimal yet. This cross-sectional study aimed to determine the intention of TB case finding among 162 public health cadres at one district. Convenient sampling technique was employed in this study. …

Data Augmentation For Deep-Learning-Based Electroencephalography, Elnaz Lashgari, Dehua Liang, Uri Maoz

Psychology Faculty Articles and Research

Background

Data augmentation (DA) has recently been demonstrated to achieve considerable performance gains for deep learning (DL)—increased accuracy and stability and reduced overfitting. Some electroencephalography (EEG) tasks suffer from low samples-to-features ratio, severely reducing DL effectiveness. DA with DL thus holds transformative promise for EEG processing, possibly like DL revolutionized computer vision, etc.

New method

We review trends and approaches to DA for DL in EEG to address: Which DA approaches exist and are common for which EEG tasks? What input features are used? And, what kind of accuracy gain can be expected?

Results

DA for DL on EEG begun …

Improvement In Patients’ Ability To Care For Anxiety And Impaired Body Image: A Case Report Of Acceptance And Commitment Therapy And Family Psychoeducation, Rasmawati Rasmawati, Budi Anna Keliat, Herni Susanti

Jurnal Keperawatan Indonesia

Heart failure and hypertension are non-communicable diseases that are responsible for 70% of deaths world wide and cause anxiety and impaired body image. Nursing interventions(therapy in general) and acceptance and commitment therapy increase patients’ acceptance of the disease and commitment to alleviate anxiety and improve impaired body image. Meanwhile, family psychoeducation improves the family’s ability to care for the patient. This case report presents two patients with heart failure and hypertension. The two patients experienced a decrease in symptoms on the cognitive aspects(difficulty concentrating, focusing on self, and decline body changes), affective aspects (worry, shame, and despair), physiological aspects(sleep disorders …

Nurses’ Awareness On Patient Safety Culture In A Newly Established University Hospital, Mohd Said Nurumal, Najwa Madinah Sabran, Siti Hazariah Abdul Hamid, Muhammad Kamil Che Hasan

Jurnal Keperawatan Indonesia

As a vital part of patient care delivery, patient safety culture contributes to the quality of care provided by nurses. Safe patient care is positively linked to the attitudes of nurses. This study aimed to assess the perception of nurses working in a newly established teaching hospital. A cross-sectional study involving 194 nurses from three different units was conducted by using a 24-item Hospital Survey of Patient Safety Culture. Data on gender, working unit, age, years of working, and attendance in workshops on patient safety were also collected. The majority of the nurses had a positive total score of patient …

Valsalva Maneuver To Decrease Pain Intensity During Arteriovenous Fistula Insertion In Hemodialysis Patients, Mahruri Saputra, Ikhsanuddin Ahmad Harahap, Sutomo Kasiman

Jurnal Keperawatan Indonesia

AV fistula allows external vascular access for hemodialysis patients. Because hemodialysis patients experience puncture wounds and stabbing pain approximately 300 times a year, development of methods to decrease pain intensity are of great importance. Some techniques, such as the Valsalva maneuver, are known to reduce pain. This study aims to assess the effect of the Valsalva maneuver on decreasing the intensity of AV fistula pain in patients receiving hemodialysis. The quasi-experimental research of pre and post without control applying consecutive sampling to get as many as 63 respondents. Pain intensity was measured by using the Numerical Pain Rating Scale (NPRS). …

Diet, Nutrition, And Substance Use Disorder, Mateja R. Savoie-Roskos, Ashley Yaugher, Alise Williams Condie, Gabriela Murza, Maren Wright Voss, Kandice Atisme

All Current Publications

Consuming a healthy diet can benefit everyone—especially individuals with substance use disorder (SUD), a disorder that occurs when frequent use of drugs or alcohol causes impairment, health issues, and difficulties with managing daily responsibilities (Substance Abuse and Mental Health Services Administration [SAMHSA], 2020). Although often overlooked, nutrition can play a key role in the treatment and recovery process for individuals with SUD, and should be included as part of a holistic approach toward recovery. In this fact sheet we will review how diet and nutrition are impacted during an active addiction, and the influence nutrition can have on treatment and …

Gut Microbiota-Derived Short-Chain Fatty Acids Promote Poststroke Recovery In Aged Mice, Juneyoung Lee, John D'Aigle, Louise Atadja, Victoria Quaicoe, Pedram Honarpisheh, Bhanu P Ganesh, Ahmad Hassan, Joerg Graf, Joseph Petrosino, Nagireddy Putluri, Liang Zhu, David J Durgan, Robert M Bryan, Louise D Mccullough, Venugopal Reddy Venna

Faculty, Staff and Students Publications

RATIONALE: The elderly experience profound systemic responses after stroke, which contribute to higher mortality and more severe long-term disability. Recent studies have revealed that stroke outcomes can be influenced by the composition of gut microbiome. However, the potential benefits of manipulating the gut microbiome after injury is unknown.

OBJECTIVE: To determine if restoring youthful gut microbiota after stroke aids in recovery in aged subjects, we altered the gut microbiome through young fecal transplant gavage in aged mice after experimental stroke. Further, the effect of direct enrichment of selective bacteria producing short-chain fatty acids (SCFAs) was tested as a more targeted …

Living Room Ventilation And Urban Environmental Health Case In Dki Jakarta, Evi Frimawaty, Muhammad Mundzir Kamiluddin

Journal of Environmental Science and Sustainable Development

In developing countries, on average, one out of five children die from pneumonia. Death from pneumonia is most prevalent in Southeast Asia, particularly in Indonesia. Many factors can cause pneumonia. In Jakarta, the prevalence period of pneumonia in toddlers reached 19.6‰, which is higher than the national prevalence period of only 18.5‰. This study used a cross-sectional research design to analyze the relationship between disease prevalence and risk factors simultaneously. Results showed that, out of 721 children under 5 years old investigated in this study, 31 toddlers suffered from pneumonia. Furthermore, bivariate analysis showed that two variables were related to …

Bad Heart Luck: Myocardial Infarction Related To Iatrogenic Coronary Cameral Fistula In A Heart Transplant Patient, Badre El Boussaadani, Zakaria Raiss, Amine Qat, Pascal Goube

Journal of the Saudi Heart Association

Endomyocardial biopsy (EMB) remains the gold standard method for diagnosis of cardiac allograft rejection. Complications following EMB rarely occur, however, it can lead to coronary cameral fistulae (CCF). We describe the case of a 65-year-old patient admitted for lateral STEMI related to a fistula communicating the distal part of the left anterior descending artery (LAD) with the right ventricle after EMB biopsy, which was incompletely closed with a covered stent.

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Assessment Of Left Ventricular Mechanics In Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Implantation: 2-D Speckle Tracking Imaging Study, Hesham A. Naeim, Reda Abuelatta, Faisal O. Alatawi, Lamiaa Khedr

Journal of the Saudi Heart Association

Background: Chronic pressure overload secondary to severe aortic stenosis causes impairment of left ventricular myocardial deformation and associated with adverse outcome. The present study aimed to assess the response of myocardial mechanics after transcatheter aortic valve implantation (TAVI).

Methods: Assessment of myocardial mechanics by quantification of LV longitudinal, circumferential strain and rotational deformation (apical, basal rotation and twist) by 2-D Speckle-tracking echocardiography at baseline and at midterm follow-up post-TAVI. The patients were divided into 2 groups based on baseline left ventricular ejection fraction. 46 patients had preserved LV EF ≥50% preserved ejection fraction (PEF) and 34 patients had reduced left …

Review Of Kelly Pender's Being At Genetic Risk: Toward A Rhetoric Of Care, Jillian K. Zwilling

Rhetoric of Health & Medicine

Being at Genetic Risk: Toward a Rhetoric of Care. Kelly Pender. University Park, PA, The Pennsylvania State Press, 2018. 174 pages, $69.95 hardcover. Publisher webpage: https://www.psupress.org/books/titles/978-0-271-08212-7.html

DOI: 10.5744/rhm.2020.1019

Selecting Appropriate Words For Naming The Rows And Columns Of Risk Assessment Matrices, Roger C. Jensen

Safety Health & Industrial Hygiene

The risk management systems used in occupational safety and health typically assess the risk of identified hazards using a tabular format commonly called a risk assessment matrix. Typically, columns are named with words indicating severity, and rows are named with words indicating likelihood or probability. Some risk assessment matrices use words reflecting the extent of exposure to a hazard. This project was undertaken with the aim of helping the designers of risk assessment matrices select appropriate names for the rows and columns. A survey of undergraduate students studying engineering or occupational safety and health obtained ratings of 16 English language …

2020-07-30_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-07-30_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data is updated on an ongoing basis.

The data below represents a cumulative total of confirmed COVID-19 resident cases, cumulative total of suspected and confirmed resident deaths, cumulative total of confirmed COVID-19 staff cases, and cumulative total of suspected and confirmed staff deaths reported by SNFs in Michigan since January 1, 2020. Case numbers are provisional and may change as facilities correct …

2020-07-30_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) and rapid virus antigen detection point of care (POC) tests, look for current infection. Serology (antibody) tests are used to look for the possibility of previous infection.
Source: Michigan Disease Surveillance System (MDSS) and Vital Records

The website contained the tables …

2020-07-30_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Engineered Extracellular Vesicles Loaded With Mir-124 Attenuate Cocaine-Mediated Activation Of Microglia, Ernest T. Chivero, Ke Liao, Fang Niu, Ashutosh Tripathi, Changhai Tian, Shilpa Buch, Guoku Hu

Journal Articles: Pharmacology & Experimental Neuroscience

MicroRNA-124 (miR-124), a brain-enriched microRNA, is known to regulate microglial quiescence. Psychostimulants such as cocaine have been shown to activate microglia by downregulating miR-124, leading, in turn, to neuroinflammation. We thus rationalized that restoring the levels of miR-124 could function as a potential therapeutic approach for cocaine-mediated neuroinflammation. Delivering miRNA based drugs in the brain that are effective and less invasive, however, remains a major challenge in the field. Herein we engineered extracellular vesicles (EVs) and loaded them with miR-124 for delivery in the brain. Approach involved co-transfection of mouse dendritic cells with Dicer siRNA and RVG-Lamp2b plasmid to deplete …