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Characterization Of B3galt2 And Heg1 Expression In Dorsal Root Ganglia, Alexander H. Nguyen

Browse all Theses and Dissertations

Proprioception provides unique sensory feedback about the body’s orientation in space and this sensation is essential for creating specific motor functions and coordinated movement. During neurogenesis, unique genetic markers are expressed and classified as early, transient/middle, and late markers depending on their timing of expression. This study focuses on the expression patterns of two late markers: Heg1 and B3galt2. We investigated how expression of these two markers respond to peripheral nerve injury (PNI). We cloned and generated riboprobes to detect expression of B3galt2 and Heg1 in DRGs using in situ hybridization after transection of the sciatic nerve. B3galt2 hybridization in …

醫食文字, 嶺南大學服務研習處

OSL Students' Service-Learning Project Output: Booklet

2018-19年度，嶺南大學中文系與浸會大學中醫藥學院，連同嶺南大學服務研習處、浸會大學創新服務學習中心，舉辦全港首次跨學院、跨學科的聯校服務研習計劃。 該計劃。聯校課程為大學教育資助委員會撥款資助之「香港跨院校服務學習師資培訓」計劃 (Project No. PolyU4/T&L/16-19) 的項目之一，結合新聞寫作及中醫食療保健課程，聯繫學生相互學習，並共同推廣服務學習。

在賽馬會「關愛．服務．研習@ 屯門」計劃下，第一年的活動已經完滿結束，此書總結活動成績，以學生的角度，整理出人物故事、機構資料，也有實用的中醫知識和食譜，展示中醫藥多元的資訊。

Traffic And Our Health, Atteh Akoto

Scholarship in Medicine - All Papers

Objective: The intent of this study is to find a correlation between long commute times, physical health, and mental health. Methods: Data was collected from a publicly available dataset on countyhealthrecords.org. Results: Increased percentage of lone drivers with long commutes and obese adults, positive correlation between long commuters and access to exercise opportunities, and negative correlation between long commuters and poor mental health days.

Investigating Preventable Hospitalizations And Potentially Related Factors In Ohio, Seth Guillozet

Scholarship in Medicine - All Papers

Objective: This research study aims to examine preventable hospitalization rates in Ohio and several variables to may be associated with changes in these rates. First, I will investigate how preventable hospitalization rates (PHRs) have changed in Ohio from 2016 to 2020. Additionally, Primary Care Physician (PCP) ratio will be compared from 2016 to 2020 in Ohio, looking for any change that has occurred between the years. Next, PHRs will be correlated to the percentage of population uninsured in Ohio to look for any relationship between these two variables. Finally, Ohio’s PHRs will be compared to Indiana’s for 2020, to look …

Universal Health Coverage And Hiv In Hispanic America, Jenna Frantz

Scholarship in Medicine - All Papers

Objective: This study analyzes differences between HIV statistics in Hispanic American countries that have passed UHC legislation versus those that have not passed UHC legislation. In 2017, 0.4% of the population of Latin America and 1.2% of the population of the Caribbean was living with Human Immunodeficiency Virus (HIV).1 Because of these high rates of HIV in Hispanic America, as well as the lethality of HIV if untreated, HIV statistics and treatment outcomes in Hispanic America are of great concern. Relationships between HIV statistics and Universal Health Coverage (UHC) legislation could serve as a metric for UHC performance in Hispanic …

Effectiveness Of The Mini-Balance Evaluation Systems Test (Mini-Bestest) In Evaluating Balance In The Controlled Hypertensive Elderly Population, Melanie Sich

Scholarship in Medicine - All Papers

Objective: Provide additional evidence about the relationship between controlled hypertension and balance control by evaluating individuals’ gait stability, sensorial orientation, reactive postural response, and anticipatory postural adjustment using the Mini-Balance Evaluation Systems Test (Mini-BESTest).

Methods: A total of 76 (28 controlled hypertensive, 48 non-hypertensive) individuals were evaluated with the Mini-BESTest protocol. Each of the subscores obtained from the test represented the different subdomains of postural control, and they were compared between controlled hypertensive and non-hypertensive groups using a one-way analysis of variance (ANOVA) statistical analysis.

Results: Hypertensive individuals tended to score lower than non-hypertensive individuals in the anticipatory postural adjustment …

Incidence Of Female Breast Cancer In The United States By Race And Region, Tiffany Le

Scholarship in Medicine - All Papers

Objective: Assess the distribution and incidence of female breast cancer in the United States in different races and regions of the United States. Methods: Collect and analyze CDC WONDER data from the Center for Disease and Control to see if there are varying rates of female breast cancer incidence between races and in different regions of the United States. Results: The results are expected to show a significant difference in female breast cancer incidence between races and a non-significant difference in female breast cancer incidence among different regions of the United States.

Age, Gender, And Racial Differences Between Acute Myocardial Infarction, Type 2 Diabetes, And Their Comortality, Steven Borchers

Scholarship in Medicine - All Papers

Acute myocardial infarction and type two diabetes are within the top seven causes of death in the United States and their impact on society is costly. Although there are many studies conducted about these diseases, some of the research is aged and requires more recent datasets. The objective of this research is to revel trends in these diseases, as well as in their comorbidity, relating to age, gender, and race. To conduct this research, data has been collected from the CDC Wonder dataset using their comorbidity database. This comorbidity data uses USA death certificates from 1999-2017 to retrieve the medical …

Correlations Between Quality Of Life, Daily Sunlight, And Suicide Risk, Brittany Abeldt

Scholarship in Medicine - All Papers

Methods: Data was collected from the archives provided by the CDC Wonder database; including The Behavioral Risk Factor Surveillance System, The North America Land Data Assimilation System, and The Web-Based Injury Statistic Query and Reporting System. The variables used were quality of life (as measured by mental health days and physical health days), suicide rates, and daily sunlight. Data was obtained for all the states in the United States, excluding Alaska and Hawaii due to lack of available data from these states. Quality of life and suicide rate data was from 2016 and daily sunlight data was from January 1st, …

Cardiovascular Fitness And Muscle Strength In Asthmatic Children, Kaitlynne Pak

Scholarship in Medicine - All Papers

Objective: The aim of this retrospective study is to evaluate the cardiovascular fitness and muscle strength performance of children with asthma versus without.

Methods: Participants include patients who were involved in the 2012 NHANES National Youth Fitness Survey (NNYFS) as published by the Centers for Disease Control and Prevention. The average cardiovascular fitness and muscle strength scores will be appreciated by analyzing the averages of time spent on treadmill, maximal heart rate, heart rate at end of exam, recovery time, maximal endurance time, cardiovascular fitness report, upper body strength and lower body strength using two-tailed T-tests between patients with asthma …

The Impact Of Food Insecurity On Diabetes Prevalence In The Us: A Look At The Northeast And The Midwest, Richard Mensah

Scholarship in Medicine - All Papers

Diabetes is one of the most common chronic conditions globally. Various risk factors have been found to be associated with the incidence of diabetes. These include genetic predispositions, physical activity and diet. However, less attention has been given to the potential risk of food insecurity to diabetes prevalence. Therefore, the goal of this study was to look at the prevalence of food insecurity and diabetes in New York and Ohio, and try to see if a correlation exists between food insecurity and diabetes prevalence in these states.

In our methods, we used the 2019 data from County Health Rankings (CHR) …

Long-Term Survival Of Bladder Cancer Metastatic To Femoral Neck Treated With Chemotherapy, Radiation, And Arthroplasty: A Case Report, John Defant, Scott Huff, Joseph D. Henningsen, Anil Krishnamurthy

Scholarship in Medicine - All Papers

Case: A 64-year-old male suffered a pathologic left femoral neck fracture. Biopsy demonstrated metastatic urothelial cancer with a non-muscle invasive bladder cancer primary confirmed by cystoscopy. Patient underwent hemiarthroplasty, chemotherapy, radiation, and eventually, a conversion to total hip arthroplasty. Today, over a decade from initial surgery, the patient remains alive and highly functional. To our knowledge, this is the only report of bone metastatic bladder cancer with over 10-year survival. Conclusion: Bladder cancer metastatic to bone has a 5-year survival rate of 3%. Surgical resection of metastasis with reconstruction may confer a survival benefit in bony oligometastatic bladder cancer.

Syringe Exchange Programs And Emergency Department Use For Drug Overdoses In Kentucky, Timothy Williams

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

In 2015, syringe exchange programs (SEPs) were legalized in Kentucky as part of a response to the high and rising morbidity and mortality associated with injection drug use, particularly opioids. In addition to their primary function of preventing the spread of some infectious diseases by providing injection drug users (IDUs) with easy access to sterile injection equipment, SEPs may also offer ancillary services such as referrals to primary care providers and substance abuse and mental health treatment, as well as safe injection education and naloxone training. These ancillary services are intended to improve the overall health of IDUs and the …

A Rapid Review Of Physician Burden Secondary To Electronic Health Records Use In The United States From 2015 To 2020, Lori Wong

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: After the passing of the Health Information Technology for Economic and Clinical Health (HITECH) Act in 2009, there has been a tremendous increase in the number of hospitals and providers adopting and using Electronic Health Records (EHRs). While EHRs were a way of improving efficiency, quality, and safety of healthcare, there is emerging evidence that they are contributing to physician burden, which can take the form of increased workload, decreased satisfaction, negative attitudes, and burnout. For instance, Arndt et al. found that physicians spent half of their workday on the EHR during and after work, and Robertson et al. …

Hospital-Based Safe To Sleep Intervention To Decrease Sleep-Related Infant Deaths In St. Louis, Missouri, Olivia M. Pokoski

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The city of St. Louis in Missouri has an elevated infant mortality rate compared to St. Louis County, Missouri, and the United States. When controlling for race, black or African American infants are over twice as likely to die before their first birthday compared to their white counterparts. Two of the leading causes of infant death are sleep-related causes and sudden infant death syndrome (SIDS) which occur if the infant is placed in an unsafe sleeping environment. To address this burden Affinia Healthcare, Barnes Jewish Hospital, and St. Mary’s Hospital have decided to implement a hospital-based Safe to Sleep campaign. …

Growing Green Minds: Implementation Of A School Garden & Nutrition Program For The Freedom Area School District In Rural Wisconsin, Marissa Schuh

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Most children in the U.S. consume too few fruits and vegetables which is putting them at risk to develop obesity and other lifestyle diseases. The 2015-2020 Dietary Guidelines for Americans recommends that individuals should increase the amount and variety of fruits and vegetables consumed in order to prevent weight gain and other chronic diseases. Research shows that garden-based educational programs can increase children’s fruit and vegetable intake as well as change their preferences and attitudes towards eating and trying new fruits and vegetables. Incorporating a garden and nutrition curriculum into a school setting is an ideal opportunity to improve children’s …

Implementing The Fit And Strong! Program To Reduce Osteoarthritis In The Older Adult Population Of Carmel, Indiana, Lauren Alexis Bergstrom Roach

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Osteoarthritis is a health outcome most commonly experienced by older adults. As the “baby boomer” population continues to age, the demand for services for older adults also increases. Fit and Strong! is an evidence-based program that works to reduce symptoms of osteoarthritis in this population through an 8-week course of physical activity classes, taught by Fit and Strong! certified instructors. Carmel, Indiana, a city in Hamilton County, has a high percentage of older adults within its population, and community health needs assessments have indicated that Hamilton County citizens have repeatedly expressed a need for resources for older members of the …

Associations Between Occupational Therapy Students’ Approaches To Studying And Their Academic Grade Results: A Cross-Sectional And Cross-Cultural Study, Tore Bonsaksen, Ted Brown, Hua B. Lim, Kenneth Fong, Milada C. Småstuen

Journal of Occupational Therapy Education

Students’ approaches to studying are generally viewed as essential for their learning outcomes and are often described as being either deep, strategic or surface. However, research on associations between study approaches and academic outcomes among occupational therapy students are rare, as are studies that include cross-cultural comparisons. The objective of this study was to assess the degree to which the deep, strategic, and surface approaches to studying were associated with occupational therapy students’ grade point average, in the total sample and when stratified by country, while controlling for age, gender and time spent on independent study. Seven hundred and twelve …

The Subject-Centered Integrative Learning Model: A New Model For Teaching Occupational Therapy’S Distinct Value, Barb Hooper, Matthew Molineux, Wendy Wood

Journal of Occupational Therapy Education

The concept of occupation-centered education has been used to describe what programs do when they infuse occupation throughout an occupational therapy curriculum. In describing occupation-centered education, educators often describe the strategies they use to help students learn occupation, including courses about occupation, direct experience with occupation, cases and questions that connect biomedical sciences and health conditions to occupation, assignments that require students to infuse occupation into therapy, curriculum threads related to occupation, and many others. While each of these strategies is important, no conceptual model exists that defines occupation-centered education, elaborates its concepts and principles, and guides the development of …

Domestic Military Operations And The Coronavirus Pandemic, Mark P. Nevitt

Faculty Articles

In response to the novel coronavirus crisis, we are witnessing one of the largest domestic military operations in American history. This article proceeds in three parts. Part I considers the emergency authorities invoked to address the coronavirus, including the Public Health Service Act (PHSA), National Emergencies Act (NEA), and Stafford Act. Part II deals with the laws, regulations, and policies governing the military’s role as a law enforcer— including restrictions on the military’s role to quell civilian disturbances. I also briefly discuss martial law, a rarely invoked but powerful authority held at the federal, state, and local levels. Part III …

Against The "Safety Net", Matthew B. Lawrence

Faculty Articles

Then-Representative Jack Kemp and President Ronald Reagan originated the “safety net” conception of U.S. health and welfare laws in the late 1970s and early 1980s, defending proposed cuts to New Deal and Great Society programs by asserting that such cuts would not take away the “social safety net of programs” for those with “true need.” Legal scholars have adopted their metaphor widely and uncritically. This Article deconstructs the safety net metaphor and counsels against its use in understanding health and welfare laws. The metaphor is descriptively confusing because it means different things to different audiences. Some understand the safety net …

Reflections On The Effects Of Federalism On Opioid Policy, Matthew B. Lawrence

Faculty Articles

One thing we have seen today that we talk about in health law all the time is how the policy, the laws and institutions up at the 10,000 foot level, can so dramatically influence the personal, people’s lived experiences. Our speakers today have done a really great job of drawing out abstract institutional questions and also showing us how those questions have influenced the lives of real people in often tragic ways. Another thing we have seen that we talk about in administrative law all the time is the importance of expertise, especially given how hard it is to trace …

Changing The Subject Of Sati, Deepa Das Acevedo

Faculty Articles

Charan Shah's 1999 death was widely considered to be the first sati, or widow immolation, to have occurred in India in over twenty years. Media coverage of the event focused on procedural minutiae-her sari, her demeanor-and ultimately, several progressive commentators came to the counterintuitive conclusion that the ritually anomalous nature of Charan's death confirmed its voluntary, secular, and noncriminal nature. This article argues that the "unlabeling" of Charan's death, like those of other women between 1999 and 2006, reflects a tension between the nonindividuated, impervious model of personhood exemplified by sati and the particularized citizen-subject of liberal-democratic politics in India.

Essentializing Labor Before, During, And After The Coronavirus Pandemic, Deepa Das Acevedo

Faculty Articles

In the era of COVID-19, the term essential labor has become part of our daily lexicon. Between March and May 2020, essential labor was not just the only kind of paid labor occurring across most of the United States; it was also, many argued, the only thing preventing utter economic and humanitarian collapse. As a result of this sudden significance, legal scholars, workers’ advocates, and politicians have scrambled to articulate exactly what makes essential labor “essential.” Some commentators have also argued that the rise of essential labor as a conceptual category disrupts—or should disrupt—longstanding patterns in the way the nation …

Effect Of Bubaline Blood-Derived Platelet Rich Fibrin (Prf) In Canine Periodontitis, Poranee Banyatworakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Periodontal disease is one of the most common oral disease in elderly dogs. The effect of periodontal disease is generalized contribute to several systemic conditions. Bioactive surgical additives have been introduced in small animal treatment to reduce inflammation and to enhance periodontal healing. Platelet-rich fibrin (PRF), a clumping of platelets, leucocyte, growth factors and cytokines trapping in a dense fibrin meshworks, is considered as a novel healing biomaterial. Autologous PRF have been demonstrated an excellent response in canine periodontal regeneration. However, a complicated health status should be concerned to obtain a high volume. Xenogenic blood donor is now focusing to …

Genetic And Pathological Investigations Of Viruses In Rabies-Negative Brain Of Cats And Dogs, Sabrina Wahyu Wardhani

Chulalongkorn University Theses and Dissertations (Chula ETD)

All year round, The Thai Red Cross Society received more than 100 animal samples that were suspected for rabies to be tested. Most of these animals were suspected for rabies due to the clinical signs of neurological disorder they developed before they die. Interestingly, in greater number of cases, rabies infection was ruled out as the cause of neurological disorder by direct fluorescent antibody test (dFAT). In respect to the importance of virus in the outcome of neurological disorder, this study was initiated to investigate the underlying cause of viral infection in the brain of rabies-negative cats and dogs that …

Effect Of Foam Pad Balance Exercise In Individual With Cancer Undergoing Chemotherapy, Chanatsupang Saraboon

Chulalongkorn University Theses and Dissertations (Chula ETD)

Background: People with cancer undergoing chemotherapy usually report a decline in balance and physical function. Foam pad balance exercises improve balance and physical function in older adults. This study aimed to examine the effect of foam pad balance exercise on balance, physical function, peripheral neuropathy, and quality of life in people with cancer undergoing chemotherapy. Methods: Thirty participants were divided randomly into 2 groups: control group (CG) and balance exercise group (BG). The BG were asked to perform foam pad balance exercises 60 minutes/day, twice a week for 6 weeks, and conventional therapy. The CG was given conventional therapy only. …

Clinical Outcomes Of Implantoplasty In The Treatment Of Peri-Implantitis: A Systematic Review, Jonghann Chai

Chulalongkorn University Theses and Dissertations (Chula ETD)

Peri-implantitis is a biological complication that possibly occur following the placement of titanium dental implants. Treatments include both non-surgical and surgical modalities. During surgical procedure, several techniques have been introduced to decontaminate the infected implant surface. The aim of this systematic review was to assess the effectiveness of the implantoplasty technique in the treatment of peri-implantitis, by investigating the changes in the clinical and radiographic parameters of peri-implant tissues after treatment and assessing both the short and long-term implant survival following the implantoplasty. A systematic review was conducted by searching electronic online (PubMed, Scopus, EMBASE) databases, published between January 2000 …

ฤทธิ์การต้านมะเร็งของสารไบแซนโทนจากไลเคน Usnea Aciculifera ต่อเซลล์มะเร็งลำไส้ใหญ่และทวารหนักของมนุษย์, ณัฏธิดา เมฆสุกใส

Chulalongkorn University Theses and Dissertations (Chula ETD)

ไบแซนโทน (Bixanthones) เป็นกลุ่มสารชีวสังเคราะห์ที่มีโครงสร้างทางเคมีหลักเป็น xanthone ซึ่งเกิดจาก xanthone monomer สองโมเลกุลมาเชื่อมต่อกันด้วยพันธะแบบต่างๆแล้วเกิดเป็นสารไบแซนโทนขึ้นหลากหลายชนิดและสามารถพบได้ในแหล่งธรรมชาติ ได้แก่ พืช เชื้อรา และไลเคน ฤทธิ์ทางเภสัชวิทยาหลักของสารกลุ่มนี้ที่พบ ได้แก่ ฤทธิ์ต้านจุลชีพ ฤทธิ์ต้านอนุมูลอิสระ และฤทธิ์ต้านมะเร็ง จากการศึกษาที่ผ่านมาพบว่า สารไบแซนโทนที่สกัดได้จากพืชและเชื้อราหลายชนิดมีฤทธิ์ในการต้านเซลล์มะเร็งต่างๆ ได้ เช่น เซลล์มะเร็งเม็ดเลือดขาว (P388) เซลล์มะเร็งปอด (LL2 และ H520) เซลล์มะเร็งเต้านม (MCF-7) เซลล์มะเร็งหลอดอาหาร (TE1 และ KYSE-150) และเซลล์มะเร็งต่อมลูกหมาก (DU-145) เป็นต้น แต่อย่างไรก็ตามยังไม่เคยมีรายงานการศึกษาฤทธิ์ต้านมะเร็งและกลไกการออกฤทธิ์ของสารไบแซนโทนที่สกัดได้จากไลเคนในเซลล์มะเร็งลำไส้ใหญ่และทวารหนักมาก่อน ในงานวิจัยนี้จึงสนใจที่จะศึกษาฤทธิ์ต้านมะเร็งของสารไบแซนโทนทั้ง 8 ชนิดที่สกัดได้จากไลเคน Usnea aciculifera ในเซลล์มะเร็งลำไส้ใหญ่และทวารหนัก ได้แก่ เซลล์ HT-29 ผลการศึกษาพบว่า สารไบแซนโทนสองชนิด ได้แก่ TT-03 และ TT-08 สามารถยับยั้งการรอดชีวิตและมีความเป็นพิษต่อเซลล์มะเร็ง HT-29 มากที่สุด โดยพบว่า สารไบแซนโทน TT-08 มีความเป็นพิษต่อเซลล์ปกติ PCS201-010 น้อยกว่าสารไบแซนโทน TT-03 และมีค่าดัชนีความจำเพาะ (selectivity index) ของเซลล์ลำไส้ปกติ CRL-1790 ต่อเซลล์มะเร็ง HT-29 เท่ากับ 1.95 ดังนั้นผู้วิจัยจึงเลือกสารไบแซนโทน TT-08 มาทำการศึกษาต่อไป จากการศึกษาต่อในระดับเซลล์และโมเลกุล พบว่า สารไบแซนโทน TT-08 มีความเป็นพิษต่อเซลล์มะเร็ง HT-29 แปรผันตามความเข้มข้นและระยะเวลาที่ใช้ทดสอบโดยมีค่าความเข้มข้นที่ทำให้เซลล์ตายร้อยละ 50 เท่ากับ 3.87± 0.13, 2.05 ± 0.06 และ 1.51± 0.11 ไมโครโมลาร์ หลังจากได้รับสารนาน 24, 48 และ 72 ชั่วโมง และสามารถยับยั้งการเจริญเติบโตของเซลล์มะเร็งผ่านการชักนำให้เกิดการหยุดของวัฏจักรเซลล์ที่ระยะ S …

The Relationship Between Oral Health Literacy And Periodontal Health Status Among The Elderly In Panare, Pattani, Thailand, Panat Piyakhunakorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to determine the association between oral health literacy (OHL) and periodontal status among Thailand's older population. This cross-sectional study was conducted between 1 July and 30 September 2020 at HPHs in, Panare, Pattani, Thailand. A total of 216 independent living older adults, participated in the study. OHL data were obtained using the Thai version of Health Literacy in Dentistry (HeLD‐Th). Trained interviewers performed face-to-face interviews for oral health-related behaviours information. The periodontal status was collected through intra-oral examination by a calibrated examiner. Data were analyzed using the SPSS version 22. Mann–Whitney U tests, Chi-Square tests, and Binary …