Medicine and Health Sciences Commons^™

Postpartum Depression! One Iv And I Am Back To Happy!, Gabrielle Dubruille

All Publications

No abstract provided.

Lgbt – Gender Identification And Pharmacist Approach To Care Of The Patient, Alexandra Angel

All Publications

No abstract provided.

Putting A Red Light On Human Trafficking, Viktoria Andonova

All Publications

No abstract provided.

Updates On Human Immunodeficiency Virus (Hiv), Jose Ojeda

All Publications

No abstract provided.

What A Blood Bath! Andexxa® Makes A Splash! Current Trends In Anticoagulation Reversal, Marianela Robainas

All Publications

No abstract provided.

Updates On Human Immunodeficiency Virus (Hiv), Eduardo Martinez Sanchez

All Publications

No abstract provided.

What A Blood Bath! Andexxa® Makes A Splash! Current Trends In Anticoagulation Reversal, Michael Pasqualicchio

All Publications

No abstract provided.

Update On Oral Oncolytics, Elizabeth Osmon

All Publications

No abstract provided.

Update On Oral Oncolytics: A Focus On Hematology Drugs, Monica Tadros

All Publications

No abstract provided.

Controlled Substance Validation, Claudia Martin Diaz, Jessica Hernandez, Laura Neubauer, Eduardo Guizan Corrales

All Publications

No abstract provided.

Oral Oncolytics, Gaines Kyna Gania

All Publications

No abstract provided.

Precautions & Handling Of Hazardous Chemotherapeutic Agents, Paula Sayegh

All Publications

No abstract provided.

A Comprehensive Residency Wellness Curriculum, Michael J. Zdradzinski, James O'Shea, Timothy P. Moran, David Caro, Paula G. Gomes, Robin Huskey, Sheryl L. Heron, Michelle D. Lall

Journal of Wellness

Introduction: Resident physician burnout is an epidemic in medical education. There are several wellness curricula published, but few describe a comprehensive program to address wellness. Our objectives were to develop and pilot a longitudinal resident wellness curriculum and assess for feasibility and sustainability.

Methods: We surveyed emergency medicine (EM) residents from two residency programs in the United States to assess a baseline level of burnout using the Maslach Burnout Inventory. We developed a comprehensive and longitudinal wellness curriculum for EM residents that incorporated all domains identified by the American College of Emergency Physicians Wellness Wheel. Mindfulness practice was incorporated throughout …

Stimulus Complexity And Mouse Strain Drive Escalation Of Operant Sensation Seeking Within And Across Sessions In C57bl/6j And Dba/2j Mice., Price E. Dickson, Guy Mittleman

Faculty Research 2020

Sensation seeking is a heritable trait that is genetically correlated with substance use; the shared genetic mechanisms underlying these traits are largely unknown. The relationship of sensation seeking and substance use has practical importance because discovering genes that drive sensation seeking can reveal genes driving substance use, and quantification of sensation seeking in mice is higher throughput and less technically challenging than quantification of volitional drug use. In order to fully understand the genetic mechanisms driving sensation seeking, it is critical to first understand the nongenetic factors driving sensation seeking. In the present study, we used the operant sensation seeking …

Discovery Of A New Predominant Cytosine Dna Modification That Is Linked To Gene Expression In Malaria Parasites., Elie Hammam, Guruprasad Ananda, Ameya Sinha, Christine Scheidig-Benatar, Mylene Bohec, Peter R Preiser, Peter C Dedon, Artur Scherf, Shruthi S Vembar

Faculty Research 2020

DNA cytosine modifications are key epigenetic regulators of cellular processes in mammalian cells, with their misregulation leading to varied disease states. In the human malaria parasite Plasmodium falciparum, a unicellular eukaryotic pathogen, little is known about the predominant cytosine modifications, cytosine methylation (5mC) and hydroxymethylation (5hmC). Here, we report the first identification of a hydroxymethylcytosine-like (5hmC-like) modification in P. falciparum asexual blood stages using a suite of biochemical methods. In contrast to mammalian cells, we report 5hmC-like levels in the P. falciparum genome of 0.2-0.4%, which are significantly higher than the methylated cytosine (mC) levels of 0.01-0.05%. Immunoprecipitation of hydroxymethylated …

Fatigue In Young People With Duchenne Muscular Dystrophy, Basmah El-Aloul, Kathy N Speechley, Yi Wei, Piotr Wilk, Craig Campbell

Paediatrics Publications

AIM: To describe fatigue in Duchenne muscular dystrophy (DMD) from patients' and parents' perspectives and to explore risk factors for fatigue in children and adolescents with DMD.

METHOD: A multicentre, cross-sectional study design was used. Seventy-one patients (all males; median age 12y, age range 5-17y) identified via the Canadian Neuromuscular Disease Registry, and their parents completed questionnaires. Subjective fatigue was assessed using the Pediatric Quality of Life Inventory Multidimensional Fatigue Scale by child self-report and parent proxy-report.

RESULTS: Patients with DMD across ages and disease stages experienced greater fatigue compared to typically developing controls from published data. Sleep disturbance symptoms …

Clinical And Therapeutic Sciences Iv Php 528, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Statistical Analysis Of Social Network Change, Teresa D. Schmidt

Systems Science Friday Noon Seminar Series

We explore two statistical methods that infer social network structures and statistically test those structures for change over time: regression-based differential network analysis (R-DNA) and information theory-based differential network analysis (I-DNA). RDNA is adapted from bioinformatics and I-DNA employs reconstructability analysis. Both methods are used to analyze Medicaid claims data from one-year periods before and after the formation of the Health Share of Oregon Coordinated Care Organization (CCO). We hypothesized that Health Share’s CCO formation would be followed by several changes in the healthcare delivery network.

Application of R-DNA and I-DNA to claims data involves three steps: (a) the inference …

Brief Communication: Long-Term Absence Of Langerhans Cells Alters The Gene Expression Profile Of Keratinocytes And Dendritic Epidermal T Cells., Qingtai Su, Aurélie Bouteau, Jacob Cardenas, Balaji Uthra, Yuanyaun Wang, Cynthia Smitherman, Jinghua Gu, Botond Z. Igyártó

Department of Microbiology and Immunology Faculty Papers

Tissue-resident and infiltrating immune cells are continuously exposed to molecules derived from the local cells that often come in form of secreted factors, such as cytokines. These factors are known to impact the immune cells' biology. However, very little is known about whether the tissue resident immune cells in return also affect the local environment. In this study, with the help of RNA-sequencing, we show for the first time that long-term absence of epidermal resident Langerhans cells led to significant gene expression changes in the local keratinocytes and resident dendritic epidermal T cells. Thus, immune cells might play an active …

You Say “Goodbye,” And I Say, “Hello, Hello, Hello.”, Mary I. Fisher

Physical Therapy Faculty Publications

No abstract provided.

The Missing Moral Dimension: Perceptions Of Transgressions And The Moderating Role Of Moral Foundations On Psychological Distress, Hannah Reas

Clinical Psychology Dissertations

Anxiety and depression can be represented on a dimensional spectrum of negative affect, broadly termed psychological distress. Research has identified several factors that maintain negative emotion, but have neglected the possibility that individuals’ interpretations of moral issues in the larger macro-system affects their level of distress. Thus, the current study investigated the role of perceptions of moral transgressions, or cognitive interpretations of stimuli (“transgressions”) that violate beliefs about right and wrong, as a predictor of psychological distress. Furthermore, this study tested how perceptions of moral transgressions vary as a function of individuals’ own moral intuitions, or moral foundations. Participants ( …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern: Reports on Inference on P(X&Y) in bivariate Lomax Model
• Georgia Southern: Reports on Kernel Density Estimation Based on Progressive Type-II Censoring

Temple Stay As Transformative Travel: An Experience Of The Buddhist Temple Stay Program In Korea, Susan L. Ross, Jungyun (Christine) Hur, Jamie Hoffman

Journal of Tourism Insights

The burgeoning tourism niche called temple stay, which originated in Korea, has been marketed to Koreans and internationals as a means for travelers to become immersed in cultural heritage, learn about Buddhism, and find one’s “true self” by spending a few days to a week as a guest in a living, operational Buddhist monastery. Although this tourism segment is gaining wide-spread appeal, the temple stay phenomenon has received relatively little scholarly attention outside of Korea. The handful of papers identified on the subject that are written in English, refer to this phenomenon as constituting various segments such as rural tourism, …

Using Simulation To Develop Clinical Teaching Competencies In Nurse Educators, Julie Fitzwater

Faculty Publications

This report describes a research study to measure the effect of simulation on clinical educators’ knowledge and skills about effective formative feedback for prelicensure nursing students.

Subject Population: Clinical nurse educators who teach prelicensure nursing students in clinical education were recruited.

Research Design: Pre-test and post-test design with a simulation workshop for educators as the intervention. This was a pilot study.

Theoretical Frameworks: The theoretical frameworks guiding the research study include Meleis’ Transitions theory and the NLN Jeffries Simulation theory. Transitions theory addresses the situational transition when a nurse clinician takes on the new role of nurse educator. Simulation theory …

Spotlight On Icosapent Ethyl For Cardiovascular Risk Reduction: Evidence To Date, Xiaoming Jia, Stephanie Koh, Mahmoud Al Rifai, Roger S. Blumenthal, Salim S. Virani

Office of the Provost

Icosapent ethyl is a highly purified formulation of eicosapentaenoic acid, a type of omega-3 fatty acid contained in fish oil. While omega-3 fatty acids have long been thought to have cardioprotective benefits, the Reduction of Cardiovascular Events with EPA-Intervention Trial (REDUCE-IT) has helped to establish icosapent ethyl as an evidence-based therapy for risk reduction of atherosclerotic cardiovascular disease (ASCVD). REDUCE-IT, however, was by no means an overnight success story. Close examination of the evidence shows that the trial was a culmination of many lessons learned from previous studies. The purpose of this manuscript is to review contemporary evidence of icosapent …

Carcinoma In Situ Involving Sclerosing Adenosis On Core Biopsy: Diagnostic Pearls To Aid The Practicing Clinician And Avoid Overtreatment, Dana Richards, Alberto A. Ayala, Yun Wu, Lavinia P. Middleton

Pathology and Laboratory Medicine Faculty Publications

INTRODUCTION: Involvement of pre-existing benign lesions by ductal carcinoma in situ (DCIS) or lobular neoplasia (LN) can present difficult diagnostic challenges, and can easily cause misdiagnosis of invasive carcinoma and over-management of localized disease. Our objective was to gather the largest case series of DCIS and LN involving sclerosing adenosis (SA), and to report the characteristic features of these lesions, in order to provide histologic criteria for the diagnostician.

METHODS: Our database was searched for core biopsy material diagnosed as carcinoma in situ involving adenosis. Glass slides and pathology reports were reviewed. The cases were studied for salient features, and …

Health & Kinesiology News, Georgia Southern University

Health Sciences & Kinesiology: News & Publications (2015-2023)

• Faculty Publish Work in Physiological Reports

College Of Health Professions News, Georgia Southern University

College of Health Professions: News & Publications (2012-2023)

• College Programs Receive National Rankings
• Dean Joyner Named Health Care Hero

The Effect Of Aging On The Erp Correlates Of Feedback Processing In The Probabilistic Selection Task, Robert West, Annmarie Huet

Psychology and Neuroscience Faculty Publications

Feedback processing contributes to efficient learning, decision making, and social interaction. Studies using event-related brain potentials (ERPs) reveal that feedback processing is associated with transient ERP components over the medial frontal and posterior regions of the scalp that distinguish between positive and negative feedback. There is some evidence indicating that aging has differential effects on the ERP correlates of feedback processing in a gambling task, and the current study was designed to extend these findings to a reinforcement learning paradigm. Younger and older adults performed the probabilistic selection task while ERPs elicited by feedback cues indicating a correct or incorrect …

Older Adults Hospitalized For Pneumonia In The United States: Incidence, Epidemiology, And Outcomes., Forest W. Arnold, Andrea Reyes-Vega, Vidyulata Salunkhe, Stephen P. Furmanek, Christian Furman, Laura Morton, Anna Johan Faul, Pam Yankeelov, Julio A. Ramirez

Faculty and Staff Scholarship

OBJECTIVES: To define the current incidence, epidemiology, and mortality of older adult patients hospitalized with community-acquired pneumonia (CAP) in Louisville, KY and thus estimate the burden of CAP in the older adult population of the United States. To define risk factors associated with early and late outcomes. DESIGN: This was a secondary analysis of older adults (aged ≥65 years) from the University of Louisville Pneumonia Study, a prospective population-based cohort study of all hospitalized adults with CAP between June 1, 2014, and May 31, 2016. SETTING: The study took place in all nine acute care hospitals for adults in Louisville, …