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2020

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Full-Text Articles in Medicine and Health Sciences

Laptop For Checkout For Online Classes, March 13, 2020, University Of Northern Iowa Mar 2020

Laptop For Checkout For Online Classes, March 13, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo explaining how students can check out a UNI laptop computer for the end of the semester.


2020-03-13_Michiganoverview_Pressrelease_25, Michigan Department Of Health & Human Services Mar 2020

2020-03-13_Michiganoverview_Pressrelease_25, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The press release was obtained from Michigan's Coronavirus page, under the tab Press Releases. The direct link to the press release is https://www.michigan.gov/coronavirus/0,9753,7-406-98158-521341--,00.html


Covid-19 Update, Wku Staff Senate Mar 2020

Covid-19 Update, Wku Staff Senate

Staff Council

COVID-19 update issued by WKU Staff Senate.


Circulating Leptin Levels Are Associated With Adiposity In Survivors Of Childhood Brain Tumors., E Danielle Sims, William J. Jennings, Brianna Empringham, Adam Fleming, Carol Portwine, Donna L. Johnston, Shayna M. Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Lehana Thabane, M Constantine Samaan Mar 2020

Circulating Leptin Levels Are Associated With Adiposity In Survivors Of Childhood Brain Tumors., E Danielle Sims, William J. Jennings, Brianna Empringham, Adam Fleming, Carol Portwine, Donna L. Johnston, Shayna M. Zelcer, Shahrad Rod Rassekh, Sarah Burrow, Lehana Thabane, M Constantine Samaan

Paediatrics Publications

Survivors of Childhood Brain Tumors (SCBT) are at a higher risk of developing cardiovascular disease and type 2 diabetes compared to the general population. Adiposity is an important risk factor for the development of these outcomes, and identifying biomarkers of adiposity may help the stratification of survivors based on their cardiovascular risk or allow for early screening and interventions to improve cardiometabolic outcomes. Leptin is an adipokine that positively correlates with the adipose mass in the general population and is a predictor of adverse cardiometabolic outcomes, yet its association with adiposity in SCBT has not been studied. The aim of …


Uni Athletics Cancels All Athletics Through Academic Year, March 13, 2020, University Of Northern Iowa Mar 2020

Uni Athletics Cancels All Athletics Through Academic Year, March 13, 2020, University Of Northern Iowa

UNI Response to COVID-19

The announcement of the cancellation of all spring sports for the 2019-2020 academic year.


2020-03-13_Michiganoverview_Pressrelease_16, Michigan Department Of Health & Human Services Mar 2020

2020-03-13_Michiganoverview_Pressrelease_16, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The press release was obtained from Michigan's Coronavirus page, under the tab Press Releases. The direct link to the press release is https://www.michigan.gov/coronavirus/0,9753,7-406-98158-521638--,00.html


Sleeping Time Is Associated With Functional Limitations In A National Sample Of Older Americans, Brenda M. Vincent, Nathaniel Johnson, Grant R. Tomkinson, Ryan Mcgrath, Brian C. Clark, Bong-Jin Choi Mar 2020

Sleeping Time Is Associated With Functional Limitations In A National Sample Of Older Americans, Brenda M. Vincent, Nathaniel Johnson, Grant R. Tomkinson, Ryan Mcgrath, Brian C. Clark, Bong-Jin Choi

Education, Health & Behavior Studies Faculty Publications

Background: Engaging in healthy behaviors may help to preserve function during aging; however, it is not well understood how sleeping time is associated with functional capacity in older adults.

Aims: We sought to determine the association of sleeping time on functional limitation in a national sample of older Americans.

Methods: The analytical sample included 6,020 adults aged at least 65 years who participated in the 2007-2016 waves of the National Health and Nutrition Examination Survey. Respondents indicated their hours of sleep/week night and were categorized as <5, 5-6.5, 7-8, 8.5-9, and >9 hours of sleep/week night. Ability to complete 19 functional tasks …


Self-Harm Poisonings Among Transgender Patients: Analysis Of Toxicology Investigator’S Consortium Registry, Marna R. Greenberg Do, Mph, Facep, Natalie E. Ebeling-Koning Do, Cody R. Mcwhirter Bs, Mikayla B. Hurwitz Bs, Lexis T. Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Andrew L. Koons, Matthew D. Cook Do, Kenneth D. Katz Md, Robert D. Cannon Do, Ryan M Surmaitis Do Mar 2020

Self-Harm Poisonings Among Transgender Patients: Analysis Of Toxicology Investigator’S Consortium Registry, Marna R. Greenberg Do, Mph, Facep, Natalie E. Ebeling-Koning Do, Cody R. Mcwhirter Bs, Mikayla B. Hurwitz Bs, Lexis T. Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Andrew L. Koons, Matthew D. Cook Do, Kenneth D. Katz Md, Robert D. Cannon Do, Ryan M Surmaitis Do

Department of Emergency Medicine

No abstract provided.


Agents Of Exposure In Transgender Patient Cases Managed By A Toxicologist: An Analysis Of The Toxicology Investigator’S Consortium (Toxic) Registry, Phillip M. Grenz Do, Mikayla B. Hurwitz Bs, Cody R. Mcwhirter Bs, Lexis Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Matthew D. Cook Do, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do, Ryan M Surmaitis Do Mar 2020

Agents Of Exposure In Transgender Patient Cases Managed By A Toxicologist: An Analysis Of The Toxicology Investigator’S Consortium (Toxic) Registry, Phillip M. Grenz Do, Mikayla B. Hurwitz Bs, Cody R. Mcwhirter Bs, Lexis Laubach Bs, Gillian A. Beauchamp Md, Judith Sabino Mph, Cdp, Beth Careyva M.D., Matthew D. Cook Do, Marna R. Greenberg Do, Mph, Facep, Robert D. Cannon Do, Ryan M Surmaitis Do

Department of Emergency Medicine

No abstract provided.


Abriendo Futuros: A Program For Rural Indigenous Girls In Yucatan, Mexico, Fabiola Romero, Ludivine Cicolella, Silvana Larrea, A. Fallone, Isabel Vieitez Martínez Mar 2020

Abriendo Futuros: A Program For Rural Indigenous Girls In Yucatan, Mexico, Fabiola Romero, Ludivine Cicolella, Silvana Larrea, A. Fallone, Isabel Vieitez Martínez

Poverty, Gender, and Youth

The Abriendo Futuros (AF) program builds on the Council’s global experience of designing and implementing successful girl-centered programs in Africa, Asia, the Middle East, and Latin America and the Caribbean. AF aims to improve the living conditions of Mayan girls (10–18 years) and contribute to the achievement of gender equity in the Yucatan. The program’s community-focused strategy seeks to empower girls through interpersonal communication and participatory workshops. Girls in selected communities are divided into age groups (10–14 and 15–18) that meet weekly with a mentor in safe spaces. The program’s mentors are young women aged 20–30 from the communities, who …


Flavonoids And Other Polyphenols Act As Epigenetic Modifiers In Breast Cancer., Priyanga Selvakumar, Aja Badgeley, Paige Murphy, Hina Anwar, Urvashi Sharma, Katharine Lawrence, Ashakumary Lakshmikuttyamma Mar 2020

Flavonoids And Other Polyphenols Act As Epigenetic Modifiers In Breast Cancer., Priyanga Selvakumar, Aja Badgeley, Paige Murphy, Hina Anwar, Urvashi Sharma, Katharine Lawrence, Ashakumary Lakshmikuttyamma

College of Pharmacy Faculty Papers

Breast cancer is a common cancer that occurs due to different epigenetic alterations and genetic mutations. Various epidemiological studies have demonstrated an inverse correlation between breast cancer incidence and flavonoid intake. The anti-cancer action of flavonoids, a class of polyphenolic compounds that are present in plants, as secondary metabolites has been a major topic of research for many years. Our review analysis demonstrates that flavonoids exhibit anti-cancer activity against breast cancer occurring in different ethnic populations. Breast cancer subtype and menopausal status are the key factors in inducing the flavonoid's anti-cancer action in breast cancer. The dose is another key …


An Actigraphy-Based Validation Study Of The Sleep Disorder Inventory In The Nursing Home, Gunnhild J. Hjetland, Inger Hilde Nordhus, Ståle Pallesen, Jeffrey Cummings, Rochelle E. Tractenberg, Eirunn Thun, Eirin Kolberg, Elisabeth Flo Mar 2020

An Actigraphy-Based Validation Study Of The Sleep Disorder Inventory In The Nursing Home, Gunnhild J. Hjetland, Inger Hilde Nordhus, Ståle Pallesen, Jeffrey Cummings, Rochelle E. Tractenberg, Eirunn Thun, Eirin Kolberg, Elisabeth Flo

School of Medicine Faculty Research

Background: Disrupted sleep is common among nursing home patients with dementia and is associated with increased agitation, depression, and cognitive impairment. Detecting and treating sleep problems in this population are therefore of great importance, albeit challenging. Systematic observation and objective recordings of sleep are time-consuming and resource intensive and self-report is often unreliable. Commonly used proxy-rated scales contain few sleep items, which affects the reliability of the raters' reports. The present study aimed to adapt the proxy-rated Sleep Disorder Inventory (SDI) to a nursing home context and validate it against actigraphy. Methods: Cross-sectional study of 69 nursing home patients, 68% …


Effects Of A Dual-Task Paradigm And Gait Velocity On Dynamic Gait Stability During Stair Descent, Qipeng Song, Wei Sun, Cui Zhang, Min Mao, Li Li Mar 2020

Effects Of A Dual-Task Paradigm And Gait Velocity On Dynamic Gait Stability During Stair Descent, Qipeng Song, Wei Sun, Cui Zhang, Min Mao, Li Li

Health Sciences & Kinesiology: Faculty Publications

Falls during stair negotiation have become one of the leading causes of accidental death. The effects of a concurrent cognitive or manual dual-task paradigm on dynamic gait stability remain uncertain. How much dynamic gait stability is influenced by gait velocity is also not clear. A total of 16 healthy young females descended a staircase under three different walking conditions: descend stairs only (single task), descend stairs while performing subtraction (cognitive dual-task), and descend stairs while carrying a glass of water (manual dual-task). An eight-camera Vicon motion analysis system and a Kistler force plate embedded into the third step of the …


Second Degree Av Heart Block After Candlenut Ingestion, Andrew L. Koons Do, Lexis Laubach Bs, Alexandra Amaducci Do, Robert D. Cannon Do, Kenneth D. Katz Md, Ryan M. Surmaitis Do, Matthew D. Cook Do, Gillian A. Beauchamp Md Mar 2020

Second Degree Av Heart Block After Candlenut Ingestion, Andrew L. Koons Do, Lexis Laubach Bs, Alexandra Amaducci Do, Robert D. Cannon Do, Kenneth D. Katz Md, Ryan M. Surmaitis Do, Matthew D. Cook Do, Gillian A. Beauchamp Md

Department of Emergency Medicine

No abstract provided.


Comparison Between High- And Low-Intensity Eccentric Cycling Of Equal Mechanical Work For Muscle Damage And The Repeated Bout Effect, Georgios Mavropalias, Tomoko Koeda, Oliver R. Barley, Wayne C. K. Poon, Aiden J. Fisher, Anthony J. Blazevich, Kazunori Nosaka Mar 2020

Comparison Between High- And Low-Intensity Eccentric Cycling Of Equal Mechanical Work For Muscle Damage And The Repeated Bout Effect, Georgios Mavropalias, Tomoko Koeda, Oliver R. Barley, Wayne C. K. Poon, Aiden J. Fisher, Anthony J. Blazevich, Kazunori Nosaka

Research outputs 2014 to 2021

Purpose: We compared high- and low-intensity eccentric cycling (ECC) with the same mechanical work for changes in muscle function and muscle soreness, and examined the changes after subsequent high-intensity ECC.

Methods: Twenty men performed either high-intensity ECC (1 min × 5 at 20% of peak power output: PPO) for two bouts separated by 2 weeks (H–H, n = 11), or low-intensity (4 min × 5 at 5% PPO) for the first and high-intensity ECC for the second bout (L–H, n = 9). Changes in indirect muscle damage markers were compared between groups and bouts.

Results: At 24 h after the …


Predicting Bleeding And Thrombosis Complications In Patients With Continuous Flow Left Ventricular Assist Devices, Kyle Zacholski, William Kuan, Justin Mccann Mccann, Aric Schadler, Aaron Cook, Sara Parli, Adam Sieg Mar 2020

Predicting Bleeding And Thrombosis Complications In Patients With Continuous Flow Left Ventricular Assist Devices, Kyle Zacholski, William Kuan, Justin Mccann Mccann, Aric Schadler, Aaron Cook, Sara Parli, Adam Sieg

The VAD Journal

Background: Left ventricular assist device (LVAD) therapy has been proven to relieve heart failure symptoms and improve survival, but is not devoid of bleeding and/or thrombotic complications. Risk stratification tools have been utilized in other cardiovascular disease populations to estimate the risk of bleeding and thrombosis with and without anticoagulation, including the HAS-BLED, HEMORR2HAGES, CHADS2 and CHA2DS2-VASc models. The study objective was to evaluate the predictive value of available risk models for bleeding and thrombotic complications in patients with an LVAD within one year of implantation.

Methods: This was a retrospective, single-center analysis …


Athletic Trainers’ Perceived And Actual Knowledge Of Cupping Therapy Concepts, Stephen A. Cage, Zachary K. Winkelmann, Brandon J. Warner, Diana M. Gallegos Mar 2020

Athletic Trainers’ Perceived And Actual Knowledge Of Cupping Therapy Concepts, Stephen A. Cage, Zachary K. Winkelmann, Brandon J. Warner, Diana M. Gallegos

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: To date, there does not appear to be a study published that has examined the prevalence of clinical use and the perceived and actual knowledge of cupping therapy that clinicians possess. The purpose of this study was to determine the perceived and actual knowledge of cupping therapy among athletic trainers. Methods: 113 certified athletic trainers completed the study (age = 35 ± 10 years, years of certified experience = 12 ± 10 years). Participants were sent an electronic survey via email that assessed frequency of usage, perceived knowledge, and actual knowledge of cupping therapy. Data were downloaded and analyzed …


The Effects Of Strength And Conditioning On Functional Movement Screen™ Scores In Secondary School Basketball., Rollin Ross Dexter, Christopher P. Renggli, James May, Lindsay Larkins Mar 2020

The Effects Of Strength And Conditioning On Functional Movement Screen™ Scores In Secondary School Basketball., Rollin Ross Dexter, Christopher P. Renggli, James May, Lindsay Larkins

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: Injury prevention and mitigation are among the primary responsibilities of Athletic Trainers. Research has indicated that basketball players at the secondary-school level suffer up to 2.1 time loss injuries (TLI) per 1,000 athletic exposures (AE). It has been suggested that Functional Movement Screen (FMS™) composite and individual task scores may help determine injury risk. Researchers have suggested that a variety of strength and conditioning strategies may positively alter both composite and individual FMS™ task scores and reduce movement asymmetry. Methods: During a retrospective analysis of the records of all junior varsity and varsity basketball players at one secondary school …


Effective Treatment Of An Apparent Lateral Ankle Sprain Using A Regional Interdependent Approach With Positional Release Therapy And Mulligan Concept, Joshua K. Underwood Mar 2020

Effective Treatment Of An Apparent Lateral Ankle Sprain Using A Regional Interdependent Approach With Positional Release Therapy And Mulligan Concept, Joshua K. Underwood

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Objective: Present a pair of clinical cases demonstrating the utilization of regional interdependent (RI) evaluation and treatment in an apparent lateral ankle sprain. The utilization of both Positional Release Therapy (PRT) and Mulligan Concept (MC) on secondary school athletes with an apparent acute lateral ankle sprain are presented. Background: Lateral ankle sprains are a common injury in athletics. While the MC has been shown to be an effective manual therapy in ankle sprains, if the treatment is not pain-free it is considered not warranted. The concept of RI attempts to connect apparently unconnected dysfunctions within the body which collectively contribute …


Student Athlete Perceptions Of Athletic Trainers’ Competence Based On Appearance And Dress, Jennifer J. Rogers Mar 2020

Student Athlete Perceptions Of Athletic Trainers’ Competence Based On Appearance And Dress, Jennifer J. Rogers

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Context: Physical appearance and dress attire may be a major influence on a person’s perception of an individual’s professional competence. Objective: To examine influence of Athletic Trainer (AT) physical appearance and dress attire on student-athletes’ perception of an AT’s competence. Design: Cross-Sectional Study Setting: NATA District 5 Participants: Student athletes (n=156; female: n=71; male: n=78) from NCAA Division III and NAIA institutions participated in the study. Interventions: Participants viewed one of four Body Mass Index (BMI) specific AT images [underweight BMI=18, normal weight BMI=24, overweight BMI=30, or an obese BMI=36] while answering 36 Student Athlete Response (SAR) Form survey questions …


Effect Of Cupping Therapy On Skin Surface Temperature In Healthy Individuals, Stephen A. Cage, Brandon J. Warner, D. Mitchelle Gallegos Mar 2020

Effect Of Cupping Therapy On Skin Surface Temperature In Healthy Individuals, Stephen A. Cage, Brandon J. Warner, D. Mitchelle Gallegos

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: The purpose of this study was to examine the effect of cupping therapy on skin surface temperature, and therefore local blood flow, at the medial forearm. Methods: 32 healthy subjects [13 females (age = 21.14 ± 1.70, height = 168.00 ± 9.70 cm, mass = 67.07 ± 16.93) and 16 males (age = 21.78 ± 1.90, height = 180.62 ± 6.09, mass = 88.35 ± 14.66) participated in this study. A mark was made with a permanent marker 7 cm distal to the medial forearm. Cupping therapy was performed over this mark with the use of a plastic pump …


The Effectiveness Of An Infrapatellar Strap On Reducing Pain Associated With Patellar Tendinopathy, Jenny Toonstra, Andrea Cripps Mar 2020

The Effectiveness Of An Infrapatellar Strap On Reducing Pain Associated With Patellar Tendinopathy, Jenny Toonstra, Andrea Cripps

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: To determine the effectiveness of an infrapatellar strap on pain reduction in participants with patellar tendinopathy. Methods: Articles were identified from PubMed, CINAHL, Medline, and SportDiscus using the string “((((patellar tendinitis OR patellar tendinopathy))) AND ((cho-pat strap OR infrapatellar strap OR compression device OR brace))) AND pain” from January 2009-January 2019, resulting in nine studies. After a review of the title and abstracts, six studies were reviewed in-depth. Of these articles, four studies met the inclusion criteria. Two independent reviewers assessed the level of evidence of included studies using the Oxford Center for Evidence-Based Medicine (2009). Changes in pain …


Narrow Escape: A Novel Approach To The Endovascular Treatment Of Superior Vena Cava Syndrome Secondary To Pacemaker Leads With Excellent Long-Term Outcomes, Yury Malyshev, Sergey Ayzenberg, Sonu Sahni, Mazin Khalid, Jeffrey Le Mar 2020

Narrow Escape: A Novel Approach To The Endovascular Treatment Of Superior Vena Cava Syndrome Secondary To Pacemaker Leads With Excellent Long-Term Outcomes, Yury Malyshev, Sergey Ayzenberg, Sonu Sahni, Mazin Khalid, Jeffrey Le

Touro College of Osteopathic Medicine (New York) Publications and Research

Pacemaker or defibrillator placement is a common procedure done in more and more patients due to increased longevity and the prominence of cardiac disease. With more indications for cardiac implantable electrode devices, the devices themselves have evolved into more complex structures with more leads. The mechanical stress, risk of infection, and decreased blood flow through the superior vena cava (SVC) put patients at risk for SVC obstruction. Herein, we present a rare case of complete SVC obstruction secondary to fibrosis due to pacemaker leads which was treated with venoplasty and showed excellent long-term results. We also review the current literature …


Incorporation Of Agouti-Related Protein (Agrp) Human Single Nucleotide Polymorphisms (Snps) In The Agrp-Derived Macrocyclic Scaffold C[Pro-Arg-Phe-Phe-Asn-Ala-Phe-Dpro] Decreases Melanocortin-4 Receptor Antagonist Potency And Results In The Discovery Of Melanocortin-5 Receptor Antagonists, Zoe M. Koerperich, Mark D. Ericson, Katie T. Freeman, Robert C. Speth, Irina D. Pogozheva, Henry I. Mosberg, Carrie Haskell-Luevano Mar 2020

Incorporation Of Agouti-Related Protein (Agrp) Human Single Nucleotide Polymorphisms (Snps) In The Agrp-Derived Macrocyclic Scaffold C[Pro-Arg-Phe-Phe-Asn-Ala-Phe-Dpro] Decreases Melanocortin-4 Receptor Antagonist Potency And Results In The Discovery Of Melanocortin-5 Receptor Antagonists, Zoe M. Koerperich, Mark D. Ericson, Katie T. Freeman, Robert C. Speth, Irina D. Pogozheva, Henry I. Mosberg, Carrie Haskell-Luevano

HPD Articles

While the melanocortin receptors (MCRs) are known to be involved in numerous biological pathways, the potential roles of the MC5R have not been clearly elucidated in humans. Agouti-related protein (AgRP), an MC3R/MC4R antagonist and MC4R inverse agonist, contains an exposed β-hairpin loop composed of six residues (Arg-Phe-Phe-Asn-Ala-Phe) that is imperative for binding and function. Within this active loop of AgRP, four human missense polymorphisms were deposited into the NIH Variation Viewer database. These polymorphisms, Arg111Cys, Arg111His, Phe112Tyr, and Ala115Val (AgRP full-length numbering), were incorporated into the peptide macrocycles c[Pro-Arg-Phe-Phe-Xaa-Ala-Phe-dPro], where Xaa was Dap or Asn, to explore the functional effects …


Uni Issues New Guidance On Campus Gatherings, March 12, 2020, University Of Northern Iowa Mar 2020

Uni Issues New Guidance On Campus Gatherings, March 12, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo outlining the parameters of events that must be canceled due to the coronavirus.


The Dominant Eye: Dominant For Parvo- But Not For Magno-Biased Stimuli?, Brian K. Foutch, Carl J. Bassi Mar 2020

The Dominant Eye: Dominant For Parvo- But Not For Magno-Biased Stimuli?, Brian K. Foutch, Carl J. Bassi

Educator Preparation & Leadership Faculty Works

Eye dominance is often defined as a preference for the visual input of one eye to the other. Implicit in this definition is the dominant eye has better visual function. Several studies have investigated the effect of visual direction or defocus on ocular dominance, but there is less evidence connecting ocular dominance and monocular visual thresholds. We used the classic “hole in card” method to determine the dominant eye for 28 adult observers (11 males and 17 females). We then compared contrast thresholds between the dominant and non-dominant eyes using grating stimuli biased to be processed more strongly either by …


Anxiety, Attributions, And Marital Quality: A Mediation Model, Tara Vossenkemper Mar 2020

Anxiety, Attributions, And Marital Quality: A Mediation Model, Tara Vossenkemper

Dissertations

Marital quality plays a significant role in the physical and mental health of many people. The purpose of this study was to examine anxiety, attributions, and marital quality in a sample of females. The first two hypotheses aimed to assess the relationship between anxiety and marital quality, and the relationship between attributions and marital quality. The primary research question aimed to assess attributions as a mediator in the relationship between anxiety and marital quality. Participants (N = 358) completed a demographic questionnaire, the Quality Marriage Index (QMI; Norton, 1983), the Marital Adjustment Test (MAT; Locke & Wallace, 1959), the …


2020-03-12_Michiganoverview_Pressrelease_12, Michigan Department Of Health & Human Services Mar 2020

2020-03-12_Michiganoverview_Pressrelease_12, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The press release was obtained from Michigan's Coronavirus page, under the tab Press Releases. The direct link to the press release is https://www.michigan.gov/coronavirus/0,9753,7-406-98158-521557--,00.html


Comparisons Of Muscle Strength, Size, And Neuromuscular Function In Pre- And Post-Pubescent Males And Females, Zachary M. Gillen Mar 2020

Comparisons Of Muscle Strength, Size, And Neuromuscular Function In Pre- And Post-Pubescent Males And Females, Zachary M. Gillen

College of Education and Human Sciences: Dissertations, Theses, and Student Research

The purpose of this study was to compare measurements of muscle strength, size, and neuromuscular function of the forearm flexors in pre- and post-pubescent males and females. Forty pre-pubescent (mean ± 95% confidence interval, age = 9.79 ± 0.35 yrs, n = 10 males, n = 10 females) and post-pubescent (age = 17.23 ± 0.58 yrs, n = 10 males, n = 10 females) participants completed this study. Biceps brachii muscle cross-sectional area (CSA) and muscle volume (MV) were quantified from ultrasound images. Participants completed maximal voluntary isometric contractions (MVICs) of the forearm flexors and extensors, and submaximal isometric step …


Novel Rvd6 Stereoisomer Induces Corneal Nerve Regeneration And Wound Healing Post-Injury By Modulating Trigeminal Transcriptomic Signature, Thang L. Pham, Azucena H. Kakazu, Jiucheng He, Bokkyoo Jun, Nicolas G. Bazan, Haydee E.P. Bazan Mar 2020

Novel Rvd6 Stereoisomer Induces Corneal Nerve Regeneration And Wound Healing Post-Injury By Modulating Trigeminal Transcriptomic Signature, Thang L. Pham, Azucena H. Kakazu, Jiucheng He, Bokkyoo Jun, Nicolas G. Bazan, Haydee E.P. Bazan

School of Medicine Faculty Publications

The high-density corneal innervation plays a pivotal role in sustaining the integrity of the ocular surface. We have previously demonstrated that pigment epithelium-derived factor (PEDF) plus docosahexaenoic acid (DHA) promotes corneal nerve regeneration; here, we report the mechanism involved and the discovery of a stereospecific Resolvin D6-isomer (RvD6si) that drives the process. RvD6si promotes corneal wound healing and functional recovery by restoring corneal innervation after injury. RvD6si applied to the eye surface elicits a specific transcriptome signature in the trigeminal ganglion (TG) that includes Rictor, the rapamycin-insensitive complex-2 of mTOR (mTORC2), and genes involved in axon growth, whereas genes related …