Medicine and Health Sciences Commons^™

Popular Television’S Health And Safety Message: What Has Changed In The Past Generation?, Heather Ann Leon

Psychology Theses & Dissertations

The assertion that television has an impact on viewers is well-supported in theory and empirical research. Hundreds of researchers have conducted hundreds of studies focused on limited, specific programming content or specific effects to contribute to this evidence. However, far fewer researchers have conducted broad, comprehensive programming content analysis. One exception is a 2005 study from Will et al. examining multiple health and safety behaviors including sexual activity, driving behaviors, intoxicating and unhealthy substance use, and violence depicted in the 1997/1998 primetime television season. Results of their research showed overall that primetime television promoted the perception that the observed health- …

Network Approaches To Elucidate The Determinants Of Protein Topology And Stability, Zeinab Haratipour

Chemistry & Biochemistry Theses & Dissertations

Predicting three-dimensional structures of proteins from sequence information alone, remains one of the most profoundly challenging and intensely studied problems in basic science. It has uniquely garnered the interdisciplinary efforts of biologists, biochemists, computer scientists, mathematicians and physicists. The advancement of computational methods to study fundamental features of proteins also enables insights that are either difficult to explore experimentally or complimentary to further interpret experimental data. In the present research and through the combined development and application of molecular dynamics and network science approaches we aimed to elucidate the role of geographically important amino acids and evolutionarily conserved long-range interactions …

Mental Health Counselors' Perceptions On Preparedness In Integrated Behavioral Healthcare In Underserved Areas, Kyulee Park

Counseling & Human Services Theses & Dissertations

Integration of behavioral and primary healthcare (IBH) has been increasingly suggested as a model approach in serving historically marginalized populations, including rural, Healthcare Provider Shortage (HPSA), and Medically Underserved (MUA) communities (Coleman & Patrick, 1976; Wong et al., 2019). However, there is no evidence-based practices in interprofessional education and training for professional mental health counselors to serve as competent practitioners in integrated behavioral healthcare. This study examined the gap in interprofessional and counselor education literature by identifying the lived experiences and perceptions of mental health professionals in integrated settings and assessed the need areas in current counselor education. A phenomenological …

Impedance Analysis Of Tissues In Nspef Treatment For Cancer Therapy, Edwin Ayobami Oshin

Biomedical Engineering Theses & Dissertations

Nanosecond pulsed electric field (nsPEF) for cancer therapy is characterized by applications of high voltage pulses with low pulsed energy to induce non-thermal effects on tissues such as tumor ablation. It nonthermally treats tissues via electroporation. Electroporation is the increase in permeabilization of a cell membrane due to the application of high pulsed electric field. The objective of this study was to investigate the effect of nsPEF on tissue by monitoring the tissue’s impedance in real-time. Potato slices (both untreated and electroporated), and tumors extracted from female BALBc mice were studied. 100ns, 1-10kV pulses were applied to the tissues using …

Attitudes Of Virginia Dentists Toward Dental Therapists, Adaira Latrece Howell

Dental Hygiene Theses & Dissertations

Purpose: The purpose of this study was to determine perceptions of Virginia (VA) dentists toward Mid-Level Dental Providers, specifically dental therapists (DT), and determine if American Dental Association (ADA) membership affected attitudes. Methods: After IRB approval, data was collected with an online survey sent to 1208 VA dentists. Participants responded to 11 Likert type scale questions ranging from 1 (strongly disagree) to 7 (strongly agree) assessing their attitudes toward DTs. Participants also responded to questions regarding the appropriate level of education and supervision of a DT, as well as five demographic questions. Two multiple linear regression models were used to …

Comparison Of Motor-Enhanced And Visual-Enhanced Interventions For Grammar In Young Children With Developmental Language Disorder, Alisha P. Springle

Communication Disorders & Special Education Theses & Dissertations

Up to 7.6% of children demonstrate a developmental language disorder (DLD), which can persist through adulthood, causing difficulty with academic achievement, social relationships, and financial stability. Grammar development, as a hallmark of DLD, is an important area of need for these children. Existing grammar interventions do not clearly distinguish the sensory input techniques that meet these children’s neurobiological instructional needs. This adapted alternating treatment design study implemented intervention using systematic paired visual and verbal and systematic paired motor, i.e. standardized gestures, and verbal sensory input techniques. A moderate-strong functional relation between intervention techniques using motor supports on grammatical outcomes in …

The Prevalence And Predictive Factors Of Breast Cancer Screening Among Older Ghanaian Women, Akosua F. Agyemang, Agnes Naki Tei-Muno, Veronica Millicent Dzomeku, Emmanuel Kweku Nakua, Precious Adade Duodu, Henry Ofori Duah, Anna Boakyewaa Bentil, Pascal Agbadi

College of Nursing Faculty Research and Publications

Background

Breast cancer cases are on the rise in Ghana, with older adult women being more at risk of the disease. However, there is a paucity of current studies on factors that predict breast cancer screening among older adult women using nationally representative data. The present study, therefore, addressed this gap by estimating the prevalence of and identifying the factors that predict breast cancer screening among older adult women in Ghana.

Methods

We used the cross-sectional survey dataset of the 2014/2015 (wave II) Study on global AGEing and adult health (SAGE). A complex survey design methodology was employed to estimate …

U.S.-Born Mexican-Origin Women’S Descriptions About Their Eating Patterns, Juanita T. Garcia, Leona Vandevusse

College of Nursing Faculty Research and Publications

Introduction

Mexican origin (MO) women comprise the largest Hispanic subgroup of Latinas in the United States. This subgroup has high incidences of obesity and associated chronic diseases. Modifiable risk factors for these include unhealthy diets and eating patterns. Efforts to understand eating patterns of Hispanics have focused on primarily first-generation Hispanics. The purpose of this study was to explore U.S.-born MO women’s descriptions about eating patterns.

Method

A qualitative exploratory-descriptive study, using a thematic analysis approach, was employed. Fifteen MO women were interviewed. The participants were second to fourth generation and reported higher educational attainment, middle-income socioeconomic brackets, and English …

Understanding Etiologies Of Road Traffic Crashes, Injuries, And Death For Patients At National Hospital Abuja: A Qualitative Content Analysis Using Haddon's Matrix, Benjamin D. Holmes, Kristin Haglund, Emmanuel A. Ameh, Oluwole O. Olaomi, Uthman Uthman, Laura D. Cassidy

College of Nursing Faculty Research and Publications

Road traffic crashes and sequelae are reaching pandemic proportions globally and have currently achieved disproportionately high levels in Nigeria. Quantitative studies are accumulating in the peer-reviewed literature, but there is a paucity of qualitative research in Nigeria. Data for this study of structural and behavioral factors of road traffic crashes and injuries in Federal Capital Territory were collected in semi-structured interviews with crash survivors at National Hospital Abuja. Interviews were analyzed via qualitative content analysis, revealing crash location and participant beliefs about crash etiologies. Units of analysis were developed from participant statements and were structured within four a priori etiologic …

Laser Ablation Of Abnormal Neurological Tissue Using Robotic Neuroblate System (Laantern): Procedural Safety And Hospitalization, Robert C. Rennert, Usman Khan, Jiri Bartek, Stephen B. Tatter, Melvin Field, Brian Toyota, Peter E. Fecci, Kevin Judy, Alireza M. Mohammadi, Patrick Landazuri, Andrew E. Sloan, Albert H. Kim, Eric C. Leuthardt, Clark C. Chen

2020-Current year OA Pubs

BACKGROUND: Stereotactic laser ablation (SLA) has demonstrated potential utility for a spectrum of difficult to treat neurosurgical pathologies in multiple small and/or retrospective single-institutional series. Here, we present the safety profile of SLA of intracranial lesions from the Laser Ablation of Abnormal Neurological Tissue using Robotic NeuroBlate System (LAANTERN; Monteris Medical) multi-institutional, international prospective observational registry.

OBJECTIVE: To determine the procedural safety of SLA for intracranial lesions.

METHODS: Prospective procedural safety and hospitalization data from the first 100 treated LAANTERN patients was collected and analyzed.

RESULTS: Mean age and baseline Karnofsky Performance Status (KPS) were 51(± 17) yr and 83(± …

Ethics In Perioperative Practice—Principles And Applications, Kathryn Schroeter

College of Nursing Faculty Research and Publications

Though often difficult, ethical decision making is necessary when caring for surgical patients. Perioperative nurses have to recognize ethical dilemmas and be prepared to take action based on the ethical code outlined in the American Nurses Association's (ANA's) Code of Ethics for Nurses with Interpretive Statements. In this first of a nine‐part series that will help perioperative nurses relate the ANA code to their own area of practice, the author looks at the first statement, which emphasizes respect for people. AORN J 75 (April 2002) 818‐824.

Breast Cancer Risk, Worry, And Anxiety: Effect On Patient Perceptions Of False-Positive Screening Results, Janie M. Lee, Kathryn P. Lowry, Jessica E. Cott Chubiz, J. Shannon Swan, Tina Motazedi, Elkan F. Halpern, Anna N. A. Tosteson, G. Scott Gazelle, Karen Donelan

2020-Current year OA Pubs

OBJECTIVE: The impact of mammography screening recall on quality-of-life (QOL) has been studied in women at average risk for breast cancer, but it is unknown whether these effects differ by breast cancer risk level. We used a vignette-based survey to evaluate how women across the spectrum of breast cancer risk perceive the experience of screening recall.

METHODS: Women participating in mammography or breast MRI screening were recruited to complete a vignette-based survey. Using a numerical rating scale (0-100), women rated QOL for hypothetical scenarios of screening recall, both before and after benign results were known. Lifetime breast cancer risk was …

Modifying Genetic Epilepsies - Results From Studies On Tuberous Sclerosis Complex, Sergiusz Jozwiak, Katarzyna Kotulska, Michael Wong, Martina Bebin

2020-Current year OA Pubs

Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous disorder affecting approximately 1 in 6,000 in general population and represents one of the most common genetic causes of epilepsy. Epilepsy affects 90% of the patients and appears in the first 2 years of life in the majority of them. Early onset of epilepsy in the first year of life is associated with high risk of cognitive decline and neuropsychiatric problems including autism. Recently TSC has been recognized as a model of genetic epilepsies. TSC is a genetic condition with known dysregulated mTOR pathway and is increasingly viewed as a model …

Associations Between Breast Cancer Subtype And Neighborhood Socioeconomic And Racial Composition Among Black And White Women, Erin Linnenbringer, Arline T Geronimus, Kia L Davis, John Bound, Libby Ellis, Scarlett L Gomez

2020-Current year OA Pubs

PURPOSE: Studies of Black-White differences in breast cancer subtype often emphasize potential ancestry-associated genetic or lifestyle risk factors without fully considering how the social or economic implications of race in the U.S. may influence risk. We assess whether neighborhood racial composition and/or socioeconomic status are associated with odds of triple-negative breast cancer (TNBC) diagnosis relative to the less-aggressive hormone receptor-positive/HER2-negative subtype (HR+ /HER-), and whether the observed relationships vary across women's race and age groups.

METHODS: We use multilevel generalized estimating equation models to evaluate odds of TNBC vs. HR+ /HER2- subtypes in a population-based cohort of 7291 Black and …

Neurology Problem Based Learning With Limited Neurologist Resources Is Feasible, Irma Duncan, Xiaoqian Fang, Norma Loprez, Michael Dobbs

School of Medicine Publications

Objective: To determine if a single neurologist can lead neurology PBL for an entire medical school class and assess the effect of a neurologist assisting in facilitating during neurology module problem-based learning on student perception of knowledge gained.

Background: Problem-based learning (PBL) groups are widely becoming integrated into medical school curriculum. During each module, clinicians from the specialty area of study help conduct PBL and facilitate students through cases. For example, during the neurology module, neurologist facilitate cases pertaining to their study. At the University of Texas Rio Grande Valley (UTRGV), there is a shortage of neurologists and it is …

Towards Precision Medicine: Defining And Characterizing Adipose Tissue Dysfunction To Identify Early Immunometabolic Risk In Symptom-Free Adults From The Gemm Family Study, Ernesto Rodriguez-Ayala, Esther C. Gallegos-Cabrales, Laura Gonzalez-Lopez, Hugo A. Laviada-Molina, Rocio A. Salinas-Osornio, Edna J. Nava-Gonzalez, Irene Leal-Berumen, Claudia Escudero-Lourdes, Fabiola Escalante-Araiza, Juan Carlos Lopez Alvarenga

School of Medicine Publications

Interactions between macrophages and adipocytes are early molecular factors influencing adipose tissue (AT) dysfunction, resulting in high leptin, low adiponectin circulating levels and low-grade metaflammation, leading to insulin resistance (IR) with increased cardiovascular risk. We report the characterization of AT dysfunction through measurements of the adiponectin/leptin ratio (ALR), the adipo-insulin resistance index (Adipo-IRi), fasting/postprandial (F/P) immunometabolic phenotyping and direct F/P differential gene expression in AT biopsies obtained from symptom-free adults from the GEMM family study. AT dysfunction was evaluated through associations of the ALR with F/P insulin-glucose axis, lipid-lipoprotein metabolism, and inflammatory markers. A relevant pattern of negative associations between …

Improving Timing Of Capillary Blood Glucose Monitoring And Insulin Administration Through Patient Education, Emily Lezcano

Honors Projects

For patients with diabetes in acute care settings, researchers report that it is challenging for the healthcare team to coordinate capillary blood glucose (CBG) monitoring and insulin administration with mealtimes. If insulin dosage is calculated from CBG values that are not updated, patients may experience dosing errors and uncontrolled CBG. Uncontrolled CBG increases patients’ risk of complications. To improve diabetes management, some hospitals have implemented policies aimed at improving the coordination of CBG monitoring, insulin administration, and mealtimes. In this study, the researcher studied the effectiveness of including an educational card on patient meal trays on the timing of CBG …

Spanish Validation And Cultural Adaptation Of The Five-Word Test For The Detection Of The Neurocognitive Disorder In Older Adults [Adaptación Cultural Y Validación Al Español De La Prueba De Cinco Palabras Para Detectar El Trastorno Neurocognitivo En Adultos Mayores], Sara G. Aguilar-Navarro, Alberto José Mimenza-Alvarado, Rafael Martínez-Sánchez, Silvia Mejia-Arango, José Alberto Avila-Funes

School of Medicine Publications

Introduction: “Episodic” memory problems are common in people with cognitive impairment due to Alzheimer’s disease and related disorders. Dubois et al. developed the Five-Word Test (5WT) to evaluate episodic memory, which has proved to be an easy and valid test for identifying cognitive disorders. However, its validation and cultural adaptation from French to Spanish has not been undertaken and its usefulness in Mexican population is unknown.

Objective: Validation and cultural adaptation of the 5WT for screening minor and major neurocognitive disorder (ND) in Mexican older adults with probable Alzheimer’s disease.

Method: Two hundred and fifteen participants (70 cognitively healthy subjects, …

Leading Rural Nurse Academic Progression, Cynthia Jean Larsen

Dissertations (1934 -)

Higher levels of nurse education have been associated with improved patient outcomes and lower healthcare costs. Members of rural populations are vulnerable, having poorer outcomes than urban inhabitants on a number of health indicators. Rural nurses are more likely than urban nurses to enter practice with associates degrees. Hence, academic progression is important for rural nurses and for the health of rural patients and communities. Rural nurse leaders work to promote the academic progression of rural nurses. Grounded theory methodology was used in this study to describe the concerns of and the actions taken by nurse leaders in the promotion …

Infant Behavioral Reactivity Predicts Change In Amygdala Volume 12 Years Later, Courtney A. Filippi, Jessica F. Sachs, Dominique Phillips, Anderson M. Winkler, Andrea L. Gold, Ellen Leibenluft, Daniel S. Pine, Nathan A. Fox

School of Medicine Publications

The current study examined the link between temperamental reactivity in infancy and amygdala development in middle childhood. A sample (n = 291) of four-month-old infants was assessed for infant temperament, and two groups were identified: those exhibiting negative reactivity (n = 116) and those exhibiting positive reactivity (n = 106). At 10 and 12 years of age structural imaging was completed on a subset of these participants (n = 75). Results indicate that, between 10 and 12 years of age, left amygdala volume increased more slowly in those with negative compared to positive reactive temperament. These results provide novel evidence …

Movement In High School: Proportion Of Chinese Adolescents Meeting 24-Hour Movement Guidelines, Li Ying, Xihe Zhu, Justin A. Haegele, Yang Wen

Human Movement Studies & Special Education Faculty Publications

The purposes of this study were (a) to examine the proportions of adolescents in China who partially or fully meet three 24-h movement guidelines on physical activity, screen-time, and sleep duration and (b) to examine whether there were gender differences in the proportion of boys and girls meeting these guidelines. The sample was made up of high school adolescents from an eastern province of China (N = 1338). The participants completed a self-reported survey on demographic variables and weekly health behaviors including physical activity, screen-time, and sleep duration. A frequency analysis was conducted to summarize the number of 24-h …

The Covid-19 Pandemic And Business Law: A Series Of Posts From The Oxford Business Law Blog, Gert-Jan Boon, Markus K. Brunnermeier, Horst Eidenmueller, Luca Enriques, Aurelio Gurrea-Martinez, Kathryn Judge, Jean-Pierre Landau, Marco Pagano, Ricardo Reis, Kristin Van Zwieten

Research Collection Yong Pung How School Of Law

The COVID-19 Pandemic is the biggest challenge for the world since World War Two, warned UN Secretary General, António Guterres, on 1 April 2020. Millions of lives may be lost. The threat to our livelihoods is extreme as well. Job losses worldwide may exceed 25 million. Legal systems are under extreme stress too. Contracts are disrupted, judicial services suspended, and insolvency procedures tested. Quarantine regulations threaten constitutional liberties. However, laws can also be a powerful tool to contain the effects of the pandemic on our lives and reduce its economic fallout. To achieve this goal, rules designed for normal times …

Global Guide: Measures Adopted To Support Businesses Through The Covid-19 Crisis: Singapore, Aurelio Gurrea-Martinez

Research Collection Yong Pung How School Of Law

After the outbreak of the coronavirus (COVID-19), the Singapore Government responded with a quick and comprehensive package of legal, economic and financial measures that sought to put the economy into hibernation and avoid the destruction of jobs and viable businesses, at least while companies were unable to generate revenues and cash-flows due to a variety of factors, including travel restrictions and lockdowns imposed in many countries around the world. To that end, the Government spent SGD$97.3 billion (that is, around 20% of the country’s GDP) to support businesses, households and employees. Most of this financial support was given in the …

“This Is Something I’M Doing For Me:” The Influence Of Mexican And U.S. Culture On The Reproductive Health Decisions Of Female Adolescents Living In The San Diego/Tijuana Border Region, Vivian Maldonado, Ruvani W. Fonseka, Jay Silverman

Faculty Research, Scholarly, and Creative Activity

No abstract provided.

Opioid Agonist Therapy During Hospitalization Within The Veterans Health Administration: A Pragmatic Retrospective Cohort Analysis, Kelsey C. Priest, Travis I. Lovejoy, Honora Englander, Sarah Shull, Dennis Mccarty

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background

Hospitalization of patients with opioid use disorder (OUD) is increasing, yet little is known about opioid agonist therapy (OAT: methadone and buprenorphine) administration during admission.

Objective

Describe and examine patient- and hospital-level characteristics associated with OAT receipt during hospitalization in the Veterans Health Administration (VHA).

Participants

A total of 12,407 unique patients, ≥ 18 years old, with an OUD-related ICD-10 diagnosis within 12 months prior to or during index hospitalization in fiscal year 2017 from 109 VHA hospitals in the continental U.S.

Main Measure

OAT received during hospitalization.

Key Results

Few admissions received OAT (n = 1914; 15%) …

Potency And Breadth Of Human Primary Zikv Immune Sera Shows That Zika Viruses Cluster Antigenically As A Single Serotype, Chad M. Nix, Jonathan Salberg, Felicity J. Coulter, Bettie W. Kareko, Zoe L. Lyski, Brian L. Booty, William B. Messer

OHSU-PSU School of Public Health Faculty Publications and Presentations

The recent emergence of Zika virus as an important human pathogen has raised questions about the durability and breadth of Zika virus immunity following natural infection in humans. While global epidemic patterns suggest that Zika infection elicits a protective immune response that is likely to offer long-term protection against repeat infection by other Zika viruses, only one study to date has formally examined the ability of human Zika immune sera to neutralize different Zika viruses. That study was limited because it evaluated human immune sera no more than 13 weeks after Zika virus infection and tested a relatively small number …

Robotic-Assisted Percutaneous Coronary Intervention Through Transradial Approach: Experience In 4 Patients With Complex Lesions, Amornpol Anuwatworn, Muhammad Ali Kahn, Tomasz Stys, Marian Petrasko, Adam Stys

The Texas Heart Institute Journal

Robotic-assisted percutaneous coronary intervention can reduce the exposure of interventional cardiologists to radiation and minimize the risk of occupational orthopedic injuries from wearing heavy protective aprons. The PRECISE (Percutaneous Robotically-Enhanced Coronary Intervention) study showed the efficacy and safety of robotic-assisted procedures for relatively low-risk lesions in single coronary arteries. Several reports have described robotic-assisted treatment of complex high-risk lesions, mostly through the transfemoral approach. We report 4 cases of patients in whom we used the transradial approach to treat complex lesions in the left anterior descending coronary artery with bifurcation balloon angioplasty reconstruction (2 cases), in the ostium of the …

Strategies For Mitigating Sexual Desire Discrepancy In Relationships, Laura M. Vowels, Kristen P. Mark

Kinesiology and Health Promotion Faculty Publications

Sexual desire discrepancy, when one member of a couple experiences more or less sexual desire relative to their partner, is among the main reasons for couples to seek therapy. A great deal of prior research has examined the complexity of sexual desire and the role of sexual desire discrepancy in long-term relationships, but little research has specifically examined strategies used to mitigate sexual desire discrepancy when it arises. Thus, the purpose of the present mixed methods study was to identify the strategies that individuals in long-term relationships use during times of desire discrepancy and to address whether the use of …

Personal, Biomechanical, Psychosocial, And Organizational Risk Factors For Carpal Tunnel Syndrome: A Structural Equation Modeling Approach, Yves Roquelaure, Ronan Garlantézec, Bradley A. Evanoff, Alexis Descatha, Jean-Baptiste Fassier, Julie Bodin

2020-Current year OA Pubs

This longitudinal study aimed at exploring the direct and indirect relationships between organizational, psychosocial, biomechanical, and personal factors and carpal tunnel syndrome (CTS) in French workers. Between 2002 and 2005, 3710 workers were included in the Cosali cohort. Between 2007 and 2010, 1611 workers were re-examined using the same standardized clinical protocol. Subjects free from CTS at baseline were studied (804 men and 563 women). We used structural equation models to examine the relationships between incident CTS cases and organizational (machine-paced work or work pace dependent on customers' demand), psychosocial (job strain model), biomechanical (Borg's rating perceived exertion, wrist bending, …

Assessment Of Benefit Of Advanced Inflammatory Bowel Disease Training: Challenges And Solutions, Kelly C Cushing, Tomer Adar, Matthew Ciorba, Ashwin N Ananthakrishnan

2020-Current year OA Pubs

BACKGROUND: Advanced inflammatory bowel disease (IBD) fellowships are available for gastroenterologists who wish to increase their expertise in complex IBD. However, little is known about the outcomes of such training. The aims of this study were to assess clinical and academic outcomes following advanced training in IBD.

METHODS: We surveyed gastroenterologists who completed advanced IBD fellowships and compared competency and outcomes to gastroenterologists focusing in IBD who completed gastroenterology training alone. Participants completed a survey via REDCap. Continuous variables were compared using the Wilcoxon rank-sum test. Categorical variables were compared using chi-square or Fisher's exact tests.

RESULTS: A total of …