Medicine and Health Sciences Commons^™

Dgts Production As A Phosphate Starvation Response In The Human Fungal Pathogen Candida Albicans, Caleb J. Wehling

School of Biological Sciences: Dissertations, Theses, and Student Research

Betaine lipids are a class of membrane lipids with betaine head groups. Three betaine lipids are known: diacylglyceryltrimethylhomoserine (DGTS), diacylglycerylhydroxymethylalanine (DGTA), and diacylglycerylcarboxymethylcholine (DGCC). Betaine lipids are most common in algae, although DGTS, the most common betaine lipid, is also found in many bacteria and fungi. Organisms which produce betaine lipids (especially DGTS) often don’t produce phosphatidylcholine (PtdCho), and DGTS structure resembles PtdCho structure without any phosphorous, leading to the hypothesis that betaine lipids may substitute for phospholipids in some organisms. This has been confirmed by discoveries that some organisms are capable of switching their membrane composition from PtdCho to …

Underlying Racism Within The Opioid Epidemic, Hannah L.A.S. Wilson

Brigham Young University Prelaw Review

Within the past century, the United States attempted different legal

avenues to address drug abuse. Some of these efforts made access

to drugs punishable and illegal. Others encouraged research to look

at underlying issues of drug abuse and implement those findings.

Within the past fifty years, these laws tended to treat drug addicts

as criminals instead of as persons suffering from a health crisis.

According to the FBI and Uniform Crime Reports, from the 1980’s

to the 2000’s, drug arrests rose by 1.5 million per year, while drug

usage rates stayed the same.3 The severe increase in the criminalization

and …

“En Defensa Por La Salud”: Los Actores Sociales En La Construcción Del Movimiento Social En Chile, Karina Martinez

Independent Study Project (ISP) Collection

This investigation aimed to describe the construction of the social movement for health demands in the frame of the social outbreak in Chile in October 2019. In addition to identifying the main health demands of this movement, it also had a focus on understanding the role of social organizations in the construction of the movement and placing it within the broader socio-political movement that arises from the social outbreak. The research design was qualitative and descriptive. Having been a remote investigation, it was largely based on literature review with the support of information from a semi-structured interview. Regarding the results, …

The Current State Of Migrant Health In Morocco: Pre-And Peri-Covid-19 Pandemic, Layla Babahaji

Independent Study Project (ISP) Collection

In the early 21st century, Morocco transitioned from being a predominantly transit migration country into both a transit and destination country for migrants. In 2013, the Moroccan government took significant steps to adapt the healthcare system in better integrating migrants in its policies. The government implemented the National Strategy on Immigration and Asylum that improved access to public health care for migrants. Recently, in March of 2020, Morocco declared a state of medical emergency due to the current COVID-19 pandemic that continues today. This paper addresses the effects of the COVID-19 pandemic on the current state of migrant health in …

Retroperitoneal Isolated Enteric Duplication Cyst, Fariha Fazal, Patricia Okiro

General Surgery, East Africa

Enteric duplication cysts are rare congenital malformations of the gastrointestinal tract with an estimated incidence of 1:100,000 live births. Fewer still are isolated enteric duplication cysts (IEDC). Accurate diagnosis and timely excision of IEDCs can help in avoiding possible complications including bleeding from gastric mucosa and malignant transformation later in life. Currently, in the paediatric population, there are twenty reported cases in the literature worldwide. Of these, only three have been described in the retro peritoneum. We present a retroperitoneal IEDC, which was juxtaposed to the inferior vena cava. To the best of our knowledge, this has not been reported …

Ua37/2 If This Next Apocalypse Gets Canceled Or Postponed, Tom Hunley

Faculty/Staff Personal Papers

Poem written by WKU English professor Tom Hunley during Covid-19 pandemic.

Ua37/2 We Will Survive, Tom C. Hunley

Faculty/Staff Personal Papers

Poem written by WKU English professor Tom Hunley during the Covid-19 pandemic.

Ua37/2 Love As The World Ends, Tom C. Hunley

Faculty/Staff Personal Papers

Poem written by WKU English professor Tom Hunley during Covid-19 pandemic.

Ua37/2 We Lived Happily During The Plague, Tom C. Hunley

Faculty/Staff Personal Papers

Poem written by WKU English professor Tom Hunley during the Covid-19 pandemic.

Ua37/2 Lockdown Haiku, Tom C. Hunley

Faculty/Staff Personal Papers

Haiku written by WKU English professor Tom Hunley during Covid-19 pandemic.

Supporting Self-Regulation Of Children With Adhd Using Wearables: Tensions And Design Challenges, Franceli L. Cibrian, Kimberley D. Lakes, Arya Tavakoulnia, Kayla Guzman, Sabrina Schuck, Gillian R. Hayes

Engineering Faculty Articles and Research

The design of wearable applications supporting children with Attention Deficit Hyperactivity Disorders (ADHD) requires a deep understanding not only of what is possible from a clinical standpoint but also how the children might understand and orient towards wearable technologies, such as a smartwatch. Through a series of participatory design workshops with children with ADHD and their caregivers, we identified tensions and challenges in designing wearable applications supporting the self-regulation of children with ADHD. In this paper, we describe the specific challenges of smartwatches for this population, the balance between self-regulation and co-regulation, and tensions when receiving notifications on a smartwatch …

Association Of Interleukin 10 Rs1800896 Polymorphism With Susceptibility To Breast Cancer: A Meta-Analysis., Ziyin Zhu, Ji-Bin Liu, Xi Liu, Linxue Qian

Department of Radiology Faculty Papers

Objective: To evaluate the correlation between interleukin 10 (IL-10) -1082A/G polymorphism (rs1800896) and breast cancers by performing a meta-analysis.

Methods: The Embase and Medline databases were searched through 1 September 2018 to identify qualified articles. Odds ratios (OR) and corresponding 95% confidence intervals (CIs) were applied to evaluate associations.

Results: In total, 14 case-control studies, including 5320 cases and 5727 controls, were analyzed. We detected significant associations between the IL10 -1082 G/G genotype and risk of breast cancer (AA + AG vs. GG: OR = 0.88, 95% CI = 0.80-0.97). Subgroup analyses confirmed a significant association in Caucasian populations (OR …

Global Burden Of Respiratory Infections Associated With Seasonal Influenza In Children Under 5 Years In 2018: A Systematic Review And Modelling Study, Xin Wang, You Li, Katherine L. O'Brien, Qalab Abbas, Syed Asad Ali, Respiratory Virus Global Epidemiology Network, Mohammad Tahir Yousafzai, Zulfiqar Ahmed Bhutta, Sajid Bashir Soofi, Anita K. M. Zaidi

Department of Paediatrics and Child Health

Background: Seasonal influenza virus is a common cause of acute lower respiratory infection (ALRI) in young children. In 2008, we estimated that 20 million influenza-virus-associated ALRI and 1 million influenza-virus-associated severe ALRI occurred in children under 5 years globally. Despite this substantial burden, only a few low-income and middle-income countries have adopted routine influenza vaccination policies for children and, where present, these have achieved only low or unknown levels of vaccine uptake. Moreover, the influenza burden might have changed due to the emergence and circulation of influenza A/H1N1pdm09. We aimed to incorporate new data to update estimates of the global …

Reducing Risk Among Sorority New Members, Juliana G. Nikolich

Senior Theses

This thesis project served to develop harm-reduction strategies for the Panhellenic sorority community at the University of South Carolina and evaluate their effectiveness. These initiatives began with a focus on the 1,445 new members that accepted sorority bids in August 2019 and expanded to include initiated members, resulting in 4,414 total members being included in this project. Multiple strategies were implemented, including new member surveys, peer-led discussions, mentor education, alternative sober events, online risk assessments, and harm reduction interventions before high-risk events. While new members displayed increased drinking frequency and consumption amounts throughout the duration of their sorority membership, they …

Perspectives Of Health Professionals And Associations On The Use Of Electronic Cigarettes For Smoking Cessation, Rowdy Fitzpatrick

Senior Theses

In an effort to deduce the current perspective of health professionals and health associations on electronic cigarettes, this project reviews position statements and policy guidelines, as well as studies regarding physician practices and knowledge, and primary data collected from focus groups. This data is analyzed in regard to beliefs on the risks and benefits of using electronic cigarettes as harm reduction or cessation tools. The multi-pronged approach attempts to clearly demonstrate the atmosphere of the healthcare community regarding electronic cigarettes.

A Look Into The Varying Usage Patterns Of Traditional And Western Medicine Within Senegal’S Urban Centers, Sarah Smith

Independent Study Project (ISP) Collection

This paper explores the usage patterns of traditional medicine and western medicine in Senegal’s urban centers of Dakar and Thiès and the factors that influence these patterns. I argue that the most influential factors in determining which medicine is used by an individual are accessibility, efficacy, and personal preference. This research was conducted in the first and third most-populated urban centers in Senegal, presenting a unique field site due to the higher concentration of western medicine in urban areas compared to rural areas in Senegal. Qualitative methodology was used through the form of secondary sources and semi-structured interviews which allowed …

The Cultural And Systemic Influence On Substance Use Disorder, Christina Seery

Independent Study Project (ISP) Collection

The opioid epidemic is an extensive global problem, but it is not random that it is most severe in the United Sates. It is commonly believed that the individuals with substance use disorder and the health care system are at fault, however many people disregard the impact culture and systems have on substance use disorder. I tackled this gap by conducting formal qualitative interviews with experts in the field of addiction and dissecting academic work. After this research it is apparent that the American culture and institutions has made individuals vulnerable to become addicted to opioids while other similar European …

Ensuring Accountability To Affected Populations In Humanitarian Settings: "Holding Humanitarian Organizations Accountable To People.", Jazmin Williamson

Independent Study Project (ISP) Collection

Aim: This research aims to examine what guidelines and regulations help ensure that humanitarian organizations are held accountable to their beneficiary populations.

Background: Although people have always been the focus of humanitarian aid, their voice and participation didn't become a centralized part of the conversation until the 1990s and later gained real traction in the early 2000s. During these times, many new foundational documents were created to highlight the "centrality of local participation in aid." Among the documents that enshrined this new principle of population participation included the 1992 Code of Conduct for the International Red Cross and Red Crescent …

El Artista Está En Línea: E-Performance En El Tiempo De Covid-19, Ezequiel N. González

Independent Study Project (ISP) Collection

Esta investigación propone una lectura detallada y comparativa de varias e-performances creadas por el artista visual uruguayo Ernesto Rizzo y la performer argentina Susy Shock, trazando un corpus de trabajo creado durante la crisis de COVID-19 y compartido en Instagram desde finales de marzo a finales de mayo de 2020. Al centrarse en el giro digital del arte de performance debido a las particularidades de la cuarentena, esta investigación busca distinguir este momento de "e-performance", entendiendo cuáles serán sus ramificaciones para el/la artista y el arte de performance en general. Así, a través de una reflexión teórica sobre el terreno …

Los Comedores Populares Argentinos En Tiempos Del Covid-19: El Rol De Los Comedores Durante La Pandemia: El Sistema Alimentario Y La Acción Del Gobierno Argentino, Katrina Frei-Herrmann

Independent Study Project (ISP) Collection

Durante la pandemia mundial de COVID-19 a principios del 2020, muchos países enfrentaron enormes desafíos desde el punto de vista económico y de salud pública. Argentina tomó las medidas rápidas y drásticas para combatir la propagación del virus, que incluyó un largo período de cuarentena con controles muy estrictos. Esto llevó a un alto costo económico en el cual muchos trabajadores perdieron sus empleos y fuentes de ingresos. Como resultado, un creciente número de personas debieron depender de ayuda de instituciones sociales para sobrevivir o atender sus necesidades básicas como el alimento. Los comedores populares – que han existido desde …

Encuentros Intergeneracionales: Continuidades Y Reformulaciones En Las Prácticas Militantes De Las Jóvenes Integrantes De Espacios De Acompañamiento De Aborto En La Amba / Intergenerational Encounters: Continuities And Reformulations In The Activist Practices Of The Young Members Of Abortion Accompaniment Spaces In The Amba, Hannah Robinson

Independent Study Project (ISP) Collection

Debido al acceso restrictivo de los abortos legales, en los últimos diez años los espacios de acompañamiento de personas que quieren interrumpir la gestación se han convertido en un sitio importante de la militancia feminista en Argentina. Estos espacios o colectivos brindan información sobre el uso del medicamento misoprostol para abortar, conectan las personas gestantes con profesionales de salud “amigables” que garantizan el acceso al Interrupción Legal del Embarazo, y proveen apoyo durante el proceso de interrupción. Al mismo tiempo, en los últimos cinco años una marea de jóvenes ha entrado masivamente a la militancia feminista.

A través de la …

El Covid-19 Y El Derecho A La Información De Los Pueblos Indígenas En La Región De Arica Y Parinacota / Covid-19 And The Right To Information Of Indigenous Peoples In The Region Of Arica And Parinacota, Finn Odum

Independent Study Project (ISP) Collection

The present work tries to understand if the health communication programs in Chile are sufficient and, specifically, if the Chilean state guarantees the right to information of indigenous peoples in the context of COVID-19 in the Arica and Parinacota region. For this, semi-structured interviews were carried out and analyzed using the Atlas.ti software. The results showed that the indigenous peoples of Arica and Parinacota need intercultural programs that recognize their rights and cultures, and more access to information.

El presente trabajo pretende comprender si los programas de comunicación de salud en Chile son suficientes y, en específico, si el estado …

El Rol Del Gobierno En Las Campañas Sanitarias De Vih, Covid-19 E Influenza, Sydney Reyes

Independent Study Project (ISP) Collection

Research Question: What are the differences and similarities between the three health campaigns — the flu, HIV, and COVID-19 — that the Chilean government has spread to population?

Objectives: The primary objective of this study was to describe and compare the three public health campaigns — the flu, HIV, and COVID-19 — to examine the role that the Chilean government has in health education and heath promotion. The secondary objectives were to identify the differences in national health campaigns and regional campaigns as well as to show the interactions between health campaigns and indigenous people. Overall, the research project looked …

Covid 19 In U.S. Migrant Detention Centers: The Call For Freedom In The Face Of A Global Pandemic, Salma Rojas

Independent Study Project (ISP) Collection

My research paper investigates the responses of the U.S. immigration detention system to the COVID 19 pandemic and determines the capacity of the detention centers to keep detained individuals alive and healthy. As I analyze their capacities, I look to past detention center outbreaks, updated public health resources, reports on ICE facility conditions and the testimonies of migrant people who were detained during the COVID 19 crisis. The urgency of the COVID 19 pandemic is why I dedicate part of my paper to what needs to be done to prevent the situation from worsening. In drawing from these various sources, …

Two (Or More) Viruses In One Bat: A Systematic Quantitative Literature Review Of Viral Coinfection In Bats, Eli J. Kaufman

Independent Study Project (ISP) Collection

Viral coinfection is an important topic in pathogen dynamics, and can increase viral shedding and change disease outcomes. As bats are carriers of important zoonoses, such as the SARS coronaviruses, rabies, and other deadly viruses, knowing more about their coinfection dynamics is important. This quantitative systematic literature review sought to show how many papers reported bat viral coinfections, and created three databases. The first database, the SQLR database was based on searches for coinfections. The second database, the Astrovirus database was to determine how much of the literature was being missed by examining a single viral family more in depth …

The Social Dimensions Of Reproductive Health: Analyzing Disparities In Morocco Through Health Indicators And Social Determinants, Mila Sicorsky

Independent Study Project (ISP) Collection

This paper explores the social dimensions of reproductive health in Morocco through a look at its health indicators and social determinants. Existing literature discusses reproductive health differences that run on economic, social, and cultural lines. In this paper, I shed light on how best to measure and understand these disparities. The research shows that reproductive health in Morocco is most accurately indicated by maternal mortality rates (MMR), access to prenatal and postnatal visits, and access to adequate family planning. It also finds that location of residence, economic status, and women’s status are key social determinants of reproductive health in Morocco. …

Dominican Nursing Students’ Self-Reported Mastery Of International Nursing Competencies, Wady Ramirez

Dissertations

The Dominican health care system has many challenges to meet the legal and the population’s health care expectations (La Hoz, 2018; United States Agency for International Development, 2013). The purpose of this study was to evaluate how well Dominican nursing students, who have completed their internship but not yet defended their final career project, assessed themselves against a set of international nursing competencies. In addition, the purpose was to explore any differences in their self-assessments based on whether these students completed their internship at public health care centers or not. Finally, the goal was to determine to what extent do …

A Mixed-Methods Case Study Of Spiritual Formation And School Induced Stress In Student Registered Nurse Anesthetists During Hospital Residency, R. Dawn Whybrew

Doctoral Dissertations and Projects

Student registered nurse anesthetists in hospital residency undergo a rigorous schedule. For Christian nurse anesthesia students, spiritual formation may suffer due to the stressors of anesthesia residency. The purpose of this mixed-methods case study sought to understand and describe the perceived influence of participation in spiritual formation opportunities during nurse anesthesia hospital residency on students’ spiritual formation level as well as their ability to handle stressors of hospital residency. In phase one of the study, the researcher conducted a purposeful convenience sampling of 54 Junior and Senior students in a quantitative quasi-experimental design. In phase one, the participant's spiritual formation …

The Skill Of Critical Appraisal: Determining If The Results Are Valid, Julie Frantsve-Hawley Phd

The Journal of the Michigan Dental Association

This article continues the Journal's series on implementing the Evidence-Based Dentistry (EBD) process into clinical practice. The abundance of scientific literature can make finding the best evidence to answer a clinical question challenging. This article presents strategies for critically appraising literature to ensure the validity and reliability of its conclusions.Implementing evidence-based dentistry requires the adept integration of current evidence into clinical practice. A robust evidence-based approach hinges on the provider's competence in identifying and effectively applying evidence to practice. This entails addressing three key questions: 1) Are the results valid? 2) What are the results? and 3) Can the evidence …

Oral Complications In Cancer Patients: A Review Of Practical Interventions In The Dental Setting, Caroline Bissonnette Dds, Kristin Mcnamara Dds, John Kalmar Dmd, Phd

The Journal of the Michigan Dental Association

Cancer prevalence in the United States is significant, with an estimated 40% of the population experiencing this diagnosis at some point in their lives. In 2020 alone, 1,806,590 new cancer cases were projected, encompassing 53,260 cases involving oral and oropharyngeal malignancies. Amidst barriers like financial constraints and irregular dental visits (highlighted by a 2014 American Dental Association survey indicating that 32.3% of the general population avoids yearly dentist appointments), patients battling cancer often encounter not just routine dental needs, but the intricate challenges arising from their malignancy and treatments. Dental professionals, pivotal in orchestrating optimal treatment strategies for cancer patients, …