Medicine and Health Sciences Commons^™

Honors Internship Evaluation, Lauren Nolan

The Eleanor Mann School of Nursing Undergraduate Honors Theses

This paper addresses the experience of an undergraduate nursing student in a Student Nurse Intern Position. The student addresses how her position differed from a certified nursing assistant (CNA), how the position helped her to imrpove organization and time management skills, and addresses patient scenarios that were encountered during her internship. These scenarios were used to address how this student will carry her experience into her nursing practice. This paper also addresses changes that could be beneficial for future honors students participating in nursing internships.

Insight Into Student Perceptions Of Lgbtqia+ Content Inclusion In Bsn Education, Kenny Sullivan, Jae Basiliere

Honors Projects

Previous research has indicated that LGBTQIA+ clients continue to receive discriminatory care from healthcare professionals. Undergraduate nursing students (n = 24) completed a survey inquiring about their perceptions of knowledge of this vulnerable population, their preparedness to provide care, and the education they received from their BSN program. Twenty-two students’ responses, 91.67%, indicate a need for further education on the provision of care to LGBTQIA+ patients. These students demonstrated discrepancies in their perceptions and the application of their knowledge. As such, nursing programs should begin to consider providing more thorough education on this vulnerable population to prepare student nurses with …

Development Of Early Social Interactions In Infants Exposed To Artificial Intelligence From Birth, Anna Vest

Rehabilitation, Human Resources and Communication Disorders Undergraduate Honors Theses

Research suggests that technology density in a home may change interactions parents and infants in the earliest months of life. This study explored how the use of smart baby technology influenced parental perceptions of development and early social interactions. A qualitative, case methodology was used. The participants in this study were one family with newborn twins. Data was collected over a six month period using journals, field notes, and observations. Thematic coding of these materials was used to answer the questions of the study. Results suggest that use of smart technology supported the emerging parenting skills and allowed the parents …

Analyzing Leadership Opportunities Through Participant Perspective, Cathryn Yaggie Heinen

Theses/Capstones/Creative Projects

The Anatomy Academic Assistant (AAA) practicum is a peer-mentoring program that helps participants further develop leadership skills. The goal of this research was to analyze leadership qualities through participant perspective and analyze the effectiveness of the AAA practicum in enhancing these leadership qualities. A 25-question survey, measuring participant perspective, was designed to include both rating-scale questions and free response questions. Rating-scale questions used a Likert scale with a corresponding assigned value. Free response questions also provided qualitative data that was grouped into overarching themes in a generated word cloud. The assigned value averages showed that participants largely agreed with the …

Filifactor Alocis: Resilience And Manipulation Against Neutrophil Effector Functions In A Dysbiotic Oral Environment., Max N. Rogers

College of Arts & Sciences Senior Theses

Periodontitis is a multifactorial chronic inflammatory infectious disease that affects around 50% of the adult population in the USA. Neutrophils, which are the primary immune cells recruited to restore health at sites of infection, are profuse in the gingival space during oral infections. In a community-wide effort, pathogenic oral bacteria hijack neutrophil effector functions to evade killing, resulting in an uncontrollable inflammatory loop that leads into inflammation-mediated tissue injury. One of these harmful emerging oral pathogens, Filifactor alocis, has been shown to evade neutrophil killing and contribute to disease progression. The purpose of this study is to gain a …

Barriers To The Implementation Of Telehealth In Rural Communities And Potential Solutions, Mariana Barreiro, Ashley Coles, Caris Conradt, Emma Hales, Elizabeth Zellmer

Anna Vaughn School of Nursing Undergraduate Work

Telehealth is an ever-growing health care system, providing health services from a distance. Telehealth provides medical care through teletechnologies and two-way video and audio communication to connect doctors to patients. A detailed review was created to show the barriers and interventions of implementing a telehealth program in a rural area. The overall purpose of the systematic review was to find and explore relevant research and answer the question, “What are commonly encountered barriers to implementing telehealth in rural areas and what interventions can nurses implement to overcome these barriers?” The approach used to obtain quality data and research was convenience …

Religious Liberty Challenges To Health Care In The Age Of Covid-19 – Supreme Court Arguments In Little Sisters Of The Poor V. Pennsylvania, Law, Rights, And Religion Project

Center for Gender & Sexuality Law

On Wednesday, May 6, 2020 the Supreme Court will be hearing arguments (telephonically) in the most recent challenge to the Affordable Care Act’s requirement that employee health plans include contraception coverage, Little Sisters of the Poor v. Pennsylvania. The case raises the important question of whether religious liberty rights can be used to limit access to health care at a time when the nation – and the world – is experiencing one of the worst global pandemics in human history. For this reason, the issues in this case take on special significance.

Methamphetamine: A Potential Risk Factor For Neurodegenerative Conditions, Katelyn Sarlette

Physician Assistant Scholarly Project Papers

Methamphetamine (METH) is a highly addictive substance that persists to be a major drug of abuse within the United States, particularly the Midwest regions. While some of the major health ramifications are well documented, its neurological impact is not fully understood. Neurodegenerative conditions like multiple sclerosis (MS), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS) continue to increase in frequency, particularly in the Midwest, yet there is no identifiable cause. The purpose of the study was to determine if METH use can contribute to the development of neurological conditions such as MS, PD, and ALS. A literature review was conducted …

The Determination Of Phosphorylation Of Nato3 By Pka, Miranda M. Regenold

Masters Theses

One of the leading regulators of neuronal cell differentiation in the CNS is the family of basic helix–loop–helix (bHLH) transcription factors. One of these proteins, Nato3, is associated with the formation of dopaminergic neurons. Transcription factors can be regulated by kinase activity, and in order to detect the associated change of phosphorylation of Nato3, we have generated Nato3 with specific epitope tags that allow for the detection and isolation of the Nato3 protein. Through subcloning techniques and a successful transformation of the Nato3 gene with the sequences of the 3X-Flag epitope and the Myc epitope into the pcDNA3.0 vector, we …

Evidence-Based Policy And Procedure Review System, Meredith A. Stokes

Doctoral Projects

Policies and procedures guide practice and the care of patients in every field of healthcare. Incorporating best practice evidence into clinical practice is a critical step towards providing safer patient care and improved patient outcomes. The challenge has been finding a way to incorporate best practice evidence into policies and procedures. Accordingly, an evidence-based project to answer the following clinical practice question was proposed: What is an evidence-based strategy for reviewing, updating, and disseminating policies and procedures for office staff at a cancer treatment organization? Through the use of Donabedian’s Model for Quality Improvement, student created tools, and an evidence-based …

Surgical Innovations For Gerd: Comparing Outcomes Of Magnetic Sphincter Augmentation And Nissen Fundoplication, Steffani Nicole Johnston Mack

Physician Assistant Scholarly Project Papers

Gastroesophageal reflux disease (GERD) is a common chronic upper gastrointestinal disease with both objective and subjective components. It is defined as a reflux of gastric contents into the esophagus, which causes symptoms such as heartburn, regurgitation, and dysphagia. Severity of the disease is dependent on both severity of the symptoms and severity of the mucosal damage done by the reflux. While many cases of GERD can be managed with oral medication, persistent and refractory cases require surgical intervention. The purpose of this literature review is to compare the efficacy of GERD’s gold standard surgical technique, the Nissen fundoplication, with a …

Stroke As The Initial Presentation Of Takayasu's Arteritis: A Case Report, Paran Davari, Paige Sutton, Kimberly S. Jones

Neurology Faculty Publications

In this study, we report the case of a pediatric neurology stroke patient who was ultimately diagnosed with Takayasu's Arteritis. Our case describes a 14-year-old Hispanic female with no significant past medical history who presented to an outside hospital for acute onset of confusion and right sided weakness. She was given tissue plasminogen activator (TPA) at the outside hospital and transferred as a stroke alert. Initial The NIH stroke scale (NIHSS) was 12 with primarily right sided symptoms. Physical exam was also significant for asymmetric pulses and blood pressures. Imaging was significant for multifocal stenosis. She was ultimately diagnosed with …

The Β3-Adrenergic Receptor Agonist Mirabegron Improves Glucose Homeostasis In Obese Humans, Brian S. Finlin, Hasiyet Memetimin, Beibei Zhu, Amy L. Confides, Hemendra J. Vekaria, Riham H. El Khouli, Zachary R. Johnson, Philip M. Westgate, Jianzhong Chen, Andrew J. Morris, Patrick G. Sullivan, Esther E. Dupont-Versteegden, Philip A. Kern

Internal Medicine Faculty Publications

BACKGROUND. Beige adipose tissue is associated with improved glucose homeostasis in mice. Adipose tissue contains β3-adrenergic receptors (β3-ARs), and this study was intended to determine whether the treatment of obese, insulin-resistant humans with the β3-AR agonist mirabegron, which stimulates beige adipose formation in subcutaneous white adipose tissue (SC WAT), would induce other beneficial changes in fat and muscle and improve metabolic homeostasis.

METHODS. Before and after β3-AR agonist treatment, oral glucose tolerance tests and euglycemic clamps were performed, and histochemical analysis and gene expression profiling were performed on fat and muscle biopsies. PET-CT scans quantified brown adipose tissue volume and …

Myeloid-Specific Deficiency Of Pregnane X Receptor Decreases Atherosclerosis In Ldl Receptor-Deficient Mice, Yipeng Sui, Zhaojie Meng, Se-Hyung Park, Wei-Wei Lu, Christopher Livelo, Qi Chen, Tong Zhou, Changcheng Zhou

Pharmacology and Nutritional Sciences Faculty Publications

Abstract The pregnane X receptor (PXR) is a nuclear receptor that can be activated by numerous drugs and xenobiotic chemicals. PXR thereby functions as a xenobiotic sensor to coordinately regulate host responses to xenobiotics by transcriptionally regulating many genes involved in xenobiotic metabolism. We have previously reported that PXR has pro-atherogenic effects in animal models, but how PXR contributes to atherosclerosis development in different tissues or cell types remains elusive. In this study, we generated an LDL receptor-deficient mouse model with myeloid-specific PXR deficiency (PXR^ΔMyeLDLR^−/−) to elucidate the role of macrophage PXR signaling in atherogenesis. The …

Preheating-Temperature Affects Nanoleakage And Degree Of Conversion Of Dual-Cured Adhesive/Resin-Composite, Sara Adel Botros, Farid Sabry El-Askary, Zainab Diaa Soliman, Dalia Ibrahim El-Korashy

Dentistry

No abstract provided.

Oral Health-Related Quality Of Life In Us Adults With Type 2 Diabetes., Giang Truong Vu

Electronic Theses and Dissertations

This dissertation focused on the relationship between type 2 diabetes (T2DM) and oral health-related quality of life (OHRQoL) and the factors associated with this relationship in the US. The objectives of the dissertation research were a three-part process: (1) to understand the relationships of T2DM with poor OHRQoL, clarify risk and preventive factors that affect this association, and identify research gaps in the literature, (2) to analyze risk factors associated with poor OHRQoL in US adults with T2DM using a nationally representative random probability cluster sample, and (3) to apply structural equation modeling (SEM) to a simplified Andersen’s Behavioral Model …

Implementation Of Genetic Carrier Screening In The Ob Population: Healthcare Cost Impact And Recommendation Adherence, Aranza Gonzalez Cendejas

Dissertations and Theses (Open Access)

Background. The recent increases in availability of and demand for genetic testing have been observed alongside concerns regarding the appropriate ordering of such tests by providers, and subsequent unnecessary costs to the healthcare system. Professional organizations, such as ACOG and ACMG, develop guidelines to aid providers in ordering appropriate genetic testing. In this study, the ordering of carrier screening by obstetricians and genetic counselors was used to determine if duplicate genetic testing was taking place at a large academic institution along with adherence to ACOG and ACMG carrier screening guidelines.

Methods. A retrospective chart review of primigravida and multigravida women …

Nrc Health: Loyalty Insights, Grace Dickas, Allie Rauner, Keenan Allen, Utkarsh Hardia, Teckhong Lee

Honors Program: Senior Projects (Public)

One of the biggest concerns of health systems is to know how they can better serve their patients. Health systems seek to exceed patient expectations and inspire patients to return to their system for all their health needs. A patient who returns can be considered loyal to that health system. NRC Health collects patient data from over 9,000 health systems across the country. This allows it to provide data insights that inform health systems’ decisions. The ultimate goal is to increase patient loyalty for health systems by helping them understand how to serve their patients better. The team was tasked …

A Qualitative Analysis Of The Barriers Faced By Nursing Assistants And Medication Aides In The Care Of Dysphagia Residents, Lauren Kreuzberg

Honors Program: Senior Projects (Public)

Dysphagia refers to the symptom of difficulty in swallowing that accompanies several prevalent conditions in the older adult population, including amyotrophic lateral sclerosis (ALS, Lou Gehrig’s Disease), stroke, Parkinson’s Disease, Multiple Sclerosis, dementia, various cancers, and brain tumors (Allari, 2014). Many older adults who suffer from these conditions reside in nursing facilities, where most of their care is provided by certified nursing assistants (CNAs) and medication aides (MAs). However, the extent of these workers’ knowledge and competence in providing care to nursing home residents with dysphagia is vastly under-researched. The qualitative analysis investigates themes among interviews with fifteen CNAs and …

A Multifactorial Intervention To Reduce Weight Bias In Healthcare Providers, Rose M. Flinchum

Evidence-Based Practice Project Reports

No abstract provided.

Mass Matters: Increasing Mammography Rates To Underserved Women, Ingrid N. Cooper

Evidence-Based Practice Project Reports

Breast cancer is the most frequently diagnosed cancer among women in Indiana and the United States (Indiana Cancer Organization, 2019). An estimated 268,000 new cases of invasive breast cancer were diagnosed and 41,760 women died due to breast cancer in 2019 (ACS, 2019). Substantial breast cancer-related morbidity and mortality disparities persist among the underserved. Disparities in breast cancer outcomes are due to lower mammography screening rates, lack of timely follow-up of abnormal results, and lack of timely treatment initiation among women with breast cancer (Highfield et al., 2015). The purpose of this evidence-based practice project was to address low mammography …

Provider-Led Intervention For Overweight Or Obese African American Women Ages 18-65 With A Bmi 25 Kg/ M₂, Tonya A. Harvey

Evidence-Based Practice Project Reports

Overweight and obese African American women tend to suffer most from the impacts of diseases, health disparities, disabilities, and decreased qualities of life (Sutton et al., 2016). Most weight loss programs are not culturally specific, despite the benefits of dietary changes and increased physical activity for all groups. The purpose of this EBP project was to implement a provider-led program including lifestyle, dietary, and activity components to decrease weight, BMI, waist circumference and blood pressure in African American women. The Iowa Model of Evidence-Based Practice to promote quality care was used to guide the EBP project, aimed to address obesity …

The Implementation Of Diabetic Foot Care Into Primary Care, Shelby D. Strong

Evidence-Based Practice Project Reports

Diabetes mellitus (DM) is one of the most common metabolic diseases worldwide. It can lead to complications in many parts of the body and can increase overall risk of dying prematurely (World Health Organization (WHO), 2016). Diabetic peripheral neuropathy (DPN) in the feet is one of the most frequent complications of DM (Wang et al., 2017). Other lower extremity complications which can occur as a result of diabetic foot complication (DFC) includes peripheral artery disease (PAD), infection, ulcer and amputation. One of the obstacles for preventing (DFC) is the lack of examinations of the feet in clinical practice (Feitosa et …

Assessment Of Activity Levels And Perceived Barriers Or Facilitators To Physical Activity In Pregnancy At Aga Khan University Hospital, Nairobi, Kenya, Zoya Virji Lalani

Master of Medicine in Obstetrics and Gynecology

Introduction: Physical activity (PA) during pregnancy significantly reduces the risk of pregnancy related complications and positively influences maternal health and wellbeing. The American College of Obstetricians and Gynaecologists (ACOG) recommends that pregnant women can exercise moderately for 30 minutes on most days of the week, however no study has ever examined the extent to which Kenyan women are meeting these recommendations. Furthermore, attitudes and perceptions of pregnant women towards PA shape their eventual behaviour. Whilst these influencing factors have not been explored, understanding them is essential for implementing effective interventions to improve exercise participation antenatally. Objectives: This study examined the …

Vestibular Evoked Myogenic Potentials And Postural Control In Adults With Age-Related Hearing Loss, Steven Michael Doettl

Theses and Dissertations (ETD)

It is well-documented that auditory thresholds decrease with age, which can be referred to as Age-related hearing loss (ARHL). ARHL is one of the most common conditions affecting older adults and is associated with several conditions including decreased postural stability and falls. Age-related changes to auditory function have been attributed to, through histopathological study, specific degradation of the sensory, supporting, and afferent structures of the cochlea. Vestibular function, as measured through vestibular evoked myogenic potentials (VEMPs) also show decreases with age. VEMPs are a measurement of evoked potentials generated by auditory stimulation of the utricle and saccule measured through a …

Serpinb1 Effects On Human Pancreatic Ductal Cells, Praneeth Goli

College of Arts & Sciences Senior Theses

Rebuilding or expanding the body’s ability to regulate blood glucose levels by restoring or increasing the body’s ability to produce insulin, long-term, would be a major advancement in diabetes (type-1 and type-2) treatment and could serve as a potential cure [1]. Therefore, the holy grail of diabetes treatment and cure research is to regenerate or increase the insulin producing cells in diabetic individuals (type-1 and type-2) [1, 2]. SerpinB1 has been implicated as a biomolecular signal that stimulates an increase in insulin cell mass in murine and zebrafish models that exhibit physiologically normal compensatory islet hyperplasia. In humans, SerpinB1 is …

In Vitro Immune Activation By Treponema Pallidum And The Effect On Osteoclastogenesis: First Experimental Step Towards An Integration Between Osteoimmunology And Paleopathology., Emily Ann Rich

College of Arts & Sciences Senior Theses

The presence of pathogens in the human body influences the expression of pro-inflammatory cytokines by activated immune cells. These cytokines, and other factors, regulate osteoclastogenesis and osteoclast activity. Through experimental osteoimmunology, interactions between the inflammatory response and bone cell physiology may provide insight into how immune processes can be translated into the lesions or abnormalities observed in the osteological record. In this research, our objective was to determine if the cytokines produced by activated immune cells increase osteoclastogenesis and osteoclast activity. To evaluate this hypothesis, we used two main protocols, one for immune activation and one for osteoclastogenesis, that utilized …

Assessing Conduct Disturbance And Fly Ash Exposure In Children., Jillian G. Winn

College of Arts & Sciences Senior Theses

Minimal research has been conducted on fly ash (a byproduct of coal combustion) and health outcomes among exposed communities, and even less has looked at its effect on children’s behavior. This study specifically looks at fly ash exposure and conduct disturbance, using logistic regression to characterize their relationship. Conduct disturbance was gauged by t-scores of 55 or higher on the dimensions of aggression and delinquency of the Child Behavior Checklist. Fly ash exposure was determined by air and surface sampling of the children’s homes. While the odds ratios suggested fly ash exposure increases the likelihood of conduct disturbance, the results …

Teaching In Ghana: Respiratory Illnesses, Rachel Pruitt

The Eleanor Mann School of Nursing Undergraduate Honors Theses

For participants of this teaching project about respiratory illnesses related to smoke, four goals were created. Our first goal was that participants would be able to recognize the health hazards associated with the populations’ current cooking situation using wood stoves. Secondly, participants would be able to verbalize the benefits of utilizing ceramic coal pots for cooking. Another goal was that participants would be able to explain a simple way to protect their family members from smoke exposure and developing respiratory illnesses. Our final goal was that participants would be able to verbalize and/or demonstrate how to use the new ceramic …

Analyzing The Triad Diagnosis Requirement For Autism In Arkansas, Liliana Barrientos-Figueroa

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Autism Spectrum Disorder (ASD) is a developmental disorder that has steadily increased in incidence and prevalence over the last ten years. While the disorder can be diagnosed as early as two years of age, most children do not receive a diagnosis until they are about five years old. The state of Arkansas requires a triad autism diagnosis, mandating that a physician, psychologist, and speech pathologist individually evaluate and agree on a diagnosis of autism for a child. The purpose of this evaluation was to examine diagnostic practices in the 11 states that participate in the Autism and Developmental Disabilities Monitoring …