Medicine and Health Sciences Commons^™

Operationalizing The Definition Of Risk As Variability, Julia Pounds, Paul Krois, Barry C. Davis, Melissa Wishy

International Symposium on Aviation Psychology - 2017

Maintaining safety requires acknowledgingrisk. However, one’s definition of risk can depend on whether the word is being used in everyday conversation or by safety practitioners or by domain experts. Not having a commonly agreed-upon definition poses problems for those charged with identifying, reducing, and communicating about risk. In an effort to standardize the definition, the International Organization for Standardization defined risk simply as the effect of uncertainty on objectives. Still, this general definition lacks enough specificity to describe uncertainty’s positive or negative effects. Relevant information can reduce uncertainty’s potential effects if it’s not ambiguous, unreliable, incomplete, or unavailable.

Taking A Closer Look At Flight Crew Handling Of Complex Failures – Ten Case Studies, J. P. Reitsma, L. Fucke, C. Borst, M.M. Van Paassen

International Symposium on Aviation Psychology - 2017

Non-normalevents,inparticularsystemfailureswithseriousoperationalimpact arerareinflightoperations.Theseeventsarenotalwayseasytohandle by flight crews.Theaimoftheperformedstudyisto determine whereinthisprocess potential issuesmaylie.Tenincidentreportsarestudied using a newly developed operationalissueanalysisframework.Theframeworkisusedtodetermine whetherandhowthecurrentinterfacescommunicatetheinitialfunctionalimpact andfunctionalimpactdelayedintime.Additionally, resultsfrompilotinterviews arepresentedwhichidentifiedthreephasesofnon-normaleventhandling:fault detection,faultmanagementandstrategic planning. Analysisofthetencases showsthatcurrentalertsystemsaremainly supporting thefirsttwophaseswhile thestrategic planning phase, requiring higherlevelfunctionalinformation integratedintotheoperationalcontextaswellasfailureimpactlaterintime,is relyingalmostentirelyonpilot knowledge andreasoning.

Investigating Pilot’S Decision Making When Facing An Unstabilized Approach: An Eye-Tracking Study, Maxime Reynal, Frank Rister, Sebastien Scannella, Christopher Wickens, Frederic Hehais

International Symposium on Aviation Psychology - 2017

Unstabilized approach has been identified to be a major causal factor of approach-and-landing accidents (e.g. off-runway touchdowns, hard landing, tail-strikes, etc).We conducted an experimentin order to analyze pilots’ performance during such approaches. Ten type-rated, commercial pilots flew each in a B737 full-flight simulator during anunstabilizedapproach at Hamburg airport. The Pilot Flyings’ (PF) eye gazes were collected. The results revealed that half of the pilots persisted in an erroneous landing decision. These latter pilots had higher dwell time on the attitude indicator/flight director whereas the group of pilots who perfomed the go-around exhibited more fixations on the navigation display prior to …

A Trend Analysis Of Human Factors Issues In Uk Military Aviation, Sarah Weedon, Victoria Cutler, Saskia Revell

International Symposium on Aviation Psychology - 2017

Human factors issues in UK military aviation are identified and mitigated through a combination of proactive support and reactive investigations, both of which employ qualitativedata collection and analysis methods. Each piece of work to identify human factors issues is performed on a standalone basis, but a regular review is undertaken to identify common trends. In the most recent review of trends, thematic analysis was used within the framework of the Accident Route Matrix to determine the most prevalent and qualitatively important human factors issues. The thematic analysis identified a wide range of human factors issues, including resource availability, training, documentation, …

Nextgen Human Factors Accomplishments And Challenges In The Future, Edmundo A. Sierra Jr.

International Symposium on Aviation Psychology - 2017

The Federal Aviation Administration (FAA), under the Next Generation Air Transportation System (NextGen) program, made significant progress in terms of infrastructure modernization of the National Airspace System (NAS). Development of infrastructure incorporated a broad scope of human performance considerations which this paper discussesat a high level. Sincethe FAA completed much of the infrastructure modernization, focus shiftedto NextGen Transformation so that benefits can be realized. NextGen Transformation involves insuring that FAA systems are seamlessly integrated; that integrated pilot and controller procedures are in place; new roles and responsibilities are defined; and that stakeholders are informed, trained, and adapted to the NextGen …

Alerts On The Nextgen Flight Deck, Angelia Sebok, Christopher D. Wickens, Brett Walters, Karl Fennell

International Symposium on Aviation Psychology - 2017

The future generation of cockpit may substantially change the nature of displays, automation, and their implications for alerting systems. Flight deck automation and information systems imposed by NextGen will create system states that may need to be alerted. New concepts of providing continuous flight information can benefit pilot awareness. Ecological interface displayskeep the operator aware of the system status and constraints, informing the pilot of emerging concerns before an alert is triggered. Continuous auditory and tactile displays support pilot awareness without requiring focused operatorattention. Both approaches improve awareness of system state, but suffer poor operator acceptance. Automation can support pilots …

Effects Of Simulator Training For Unmanned Aerial Systems In Undergraduate Education, William Weldon, Dr. Brian Kozak

International Symposium on Aviation Psychology - 2017

Unmanned aerial systems (UAS) are being added to the national airspace (NAS) in very large numbers. Many universities have seen this demand for UAS operators and begun to create programs in order to train undergraduate students in their use. The UAS industry currently lacks adequatetraining requirements for beginning operators. This fact makes university training important, because universities are oneof the few places that offer structured training. While the UAS industry in the US is in its infancy it is possible to draw parallelismsthe training history of manned flight in order to avoid pitfalls and offer training in the most efficient …

Sources And Content Of Popular Online Videos About Autism Spectrum Disorders, Betty Kollia, Margaret T. Kamowski-Shakibai, Corey H. Basch, Ashley Clark

Communication Sciences and Disorders: Faculty Publications

Background: Our study aimed to determine source of upload and content portrayed in the 100 most-viewed videos on autism spectrum disorders (ASDs) on the video sharing public forum, YouTube. ASDs have become highly prevalent in the last decade, arousing a significant response from the media and psycho-educational health professions. Utilization of and reliance on social media for information on health matters has also proliferated. Some suggest that online videos could promote early detection (and intervention) of ASD by prompting caregivers to seek guidance. However, the usefulness of the available videos is unclear. Methods: The 100 most popular YouTube videos were …

Adolescent Food Purchasing Patterns And The Association With Dietary Intake And Body Mass Index In Rural Communities In Kentucky And North Carolina, Paige M. Connelly

Theses and Dissertations--Nutrition and Food Systems

The local food environment plays an important role in the health of adolescents, especially in rural areas. Often, rural areas lack the accessibility and availability of healthy food choices, making a healthy lifestyle difficult to achieve. This study presents a cross-sectional survey of rural adolescents in 8 counties in Kentucky and North Carolina to determine the association between food store choice, body mass index (BMI), and key dietary outcomes. Although BMI had no association with food store choice, those who infrequently shopped at gas stations, convenience stores, and fast food restaurants consumed significantly less added sugar (p < 0.05) than those who shopped at those stores more regularly. Increasing the availability and accessibility of food venues with healthy food options such as supermarkets may decrease added sugar intake among rural adolescents.

Characterization Of Malt1 Inhibitors And Their Effect On Leukemic Cell Growth Properties, Christina Snyder

Graduate School of Biomedical Sciences Theses and Dissertations

Leukemia is the most common childhood cancer, with a combined 40,000 predicted new cases in the United States in 2016 [8]. The two most common subtypes are acute myeloid leukemia (AML) and chronic lymphocytic leukemia (CLL) [9-11]. The commercially available inhibitor of Bruton’s tyrosine kinase (BTK) has shown promising results in clinical trials for CLL because of the importance of BCR signaling in CLL [12-15]. Recent studies suggest that the outgrowth of BTK inhibitor resistant clonal cells in some CLL patients results in a treatment-refractory phenotype [16-18]. MALT1, a protein involved in BCR activation of the NF-κB pathway that functions …

Application Of Incident Command Structure To Clinical Trial Management In The Academic Setting: Principles And Lessons Learned, Penny S. Reynolds, Mary J. Michael, Bruce D. Spiess

Anesthesiology Publications

Background

Clinical trial success depends on appropriate management, but practical guidance to trial organisation and planning is lacking. The Incident Command System (ICS) is the ‘gold standard’ management system developed for managing diverse operations in major incident and public health arenas. It enables effective and flexible management through integration of personnel, procedures, resources, and communications within a common hierarchical organisational structure. Conventional ICS organisation consists of five function modules: Command, Planning, Operations, Logistics, and Finance/Administration. Large clinical trials will require a separate Regulatory Administrative arm, and an Information arm, consisting of dedicated data management and information technology staff. We applied …

Directed Evolution Provides Insight Into Conformational Substrate Sampling By Srta, Muna Suliman, Vishaka Santosh, Tom C. M. Seegar, Annamarie C. Dalton, Kathryn M. Schultz, Candice S. Klug, William A. Barton

Biochemistry and Molecular Biology Publications

The Sortase family of transpeptidases are found in numerous gram-positive bacteria and involved in divergent physiological processes including anchoring of surface proteins to the cell wall as well as pili assembly. As essential proteins, sortase enzymes have been the focus of considerable interest for the development of novel anti-microbials, however, more recently their function as unique transpeptidases has been exploited for the synthesis of novel bio-conjugates. Yet, for synthetic purposes, SrtA-mediated conjugation suffers from the enzyme's inherently poor catalytic efficiency. Therefore, to identify SrtA variants with improved catalytic efficiency, we used directed evolution to select a catalytically enhanced SrtA enzyme. …

Soil-Transmitted Helminthiasis And Schistosomiasis In Children Of Poor Families In Leyte, Philippines: Lessons For Disease Prevention And Control, Harvy Joy Liwanag, Jhanna Uy, Janis Ruth Gatchalian, Betty De La Calzada, Justine Alessandra Uy, Manuel Dayrit, Ramil T. Bataller

Mathematics Faculty Publications

Objective

Neglected tropical diseases (NTDs) continue to be a public health problem in the Philippines. We assessed the association of soil-transmitted helminthiasis (STH) and schistosomiasis with selected health-related and socioeconomic variables in four villages in Leyte, Philippines.

Methods

Stool specimens from 418 adults and 533 of their children from 209 families were examined through the Kato-Katz technique.

Results

STH and schistosomiasis were present in 64.6% and 12.5%, respectively, of study participants. Analysis through the generalized linear mixed model revealed a number of associations between infection in parents and their children. Findings indicate that years of disease prevention and control efforts …

Prevalence And Associated Factors Of Illicit Drug Use Among University Students In The Association Of Southeast Asian Nations (Asean), Siyan Yi, Karl Peltzer, Supa Pengpid, Indri Hapsari Susilowati

Background: Illicit drug use among university students has been recognized as a global public health issue in recent years. It may lead to poor academic performance that in turn leads to poor productivity in their later life. This study explores prevalence of and factors associated with illicit drug use among university students in the Association of Southeast Asian Nations (ASEAN).

Methods: This multi-country cross-sectional study was conducted in 2015 in Cambodia, Indonesia, Laos, Malaysia, Myanmar, the Philippines, Singapore, Thailand and Vietnam. A multi-stage cluster sampling was used to select undergraduate students from one or two universities in each …

Patterns Of Hiv Testing, Drug Use, And Sexual Behaviors In People Who Use Drugs: Findings From A Community-Based Outreach Program In Phnom Penh, Cambodia, Gitau Mburu, Chanrith Ngin, Sovannary Tuot, Pheak Chhoun, Khuondyla Pal, Siyan Yi

Background: People who use drugs are an important priority for HIV programs. However, data related to their utilization of HIV services are limited. This paper reports patterns of HIV testing, drug use, and risk and service perception among people who use drugs. Study participants were receiving HIV and harm reduction services from a communitybased program in Phnom Penh, comprised of itinerant peer-led outreach and static drop-in centers.

Methods: This was a mixed-methods study conducted in 2014, comprising of a quantitative survey using a structured questionnaire, followed by two focus group discussions among a sub-sample of survey participants. Participants …

System Identification Of Motion Artifact: Noise In Eeg Headsets From Locomotion, Kaela Shea, James Tung

H-Workload 2017: Models and Applications (Works in Progress)

Fall prevention for geriatric populations is a growing concern among clinicians and researchers due to severe risk of morbidity and loss of independence. Emerging evidence has demonstrated that mental workload while walking influences gait stability and the risk for falling. Electroencephalography (EEG) presents a potential method to provide objective measures of mental workload, particularly during daily activities. Noise introduced to the EEG signal during motion, however, is restrictive. The study presented in the following paper isolates EEG signal noise attained from gait for a commercially accessible EEG system, the "Emotiv" Time and spectral system identification techniques were applied to model …

Online Measuring Of Available Resources, Enrique Munoz-De-Escalona, José Juan Canas

H-Workload 2017: Models and Applications (Works in Progress)

This paper present a proposal for measuring available mental resources during the accomplishment of a task. Our proposal consists in measuring emotions provoked by perceived self-efficacy in the execution of the task. Self-efficacy is one of the most important factors that affect the resources that a person puts at the disposal of the execution of the task. When a person perceives that he/she is not being effective he/she will activate more resources to improve his performance. This self-efficacy will be reflected in the emotions that the person experiences. A good efficacy will provoke positive emotions and a bad efficacy negative …

Strain Distribution In The Porcine Lumbar Laminae Under Asymmetric Loading, Colin Bright, Stephen Tiernan, Fiona Mcevoy, Patrick Kiely

Conference Papers

If the articular facets of the vertebra grow in an asymmetric manner, the developed geometry causes an asymmetry of loading. When the loading environment is altered by way of increased activity, the likelihood of acquiring a stress fracture may be increased. The combination of geometric asymmetry and increased activity is hypothesised to be the precursor to the stress fracture under investigation in this study, spondylolysis. This vertebral defect is an acquired fracture with 7% prevalence in the paediatric population. This value increases to 21% among athletes who participate in hyperextension sports. Tests were carried out on porcine lumbar vertebrae, on …

Preface: Hydrogeology And Human Health, Paul Hynds, Mark A. Borchardt, Motomu Ibaraki

Articles

In the mid-1800s, Dr. John Snow (1813–1858), an obstetrician and anaesthesiologist, theorised that cholera, a highly infectious gastrointestinal infection associated with extremely high rates of mortality, was caused by faecal contamination of water supplies (Donaldson and Scally 2009). During the summer of 1854, a significant cholera outbreak occurred in the Soho district of London (UK), resulting in the deaths of 616 people. As part of this first modern epidemiological investigation, Dr. Snow noted that “within 250 yards of the spot where Cambridge Street joins Broad Street there were upwards of 500 fatal attacks of cholera in 10 days (…) suspected …

Preclinical Assessment Of Immunocal® As A Preventative Treatment For Traumatic Brain Injury (Tbi) In A Mouse Model Of Closed Head Injury, Elizabeth Eugenia Ignowski

Electronic Theses and Dissertations

Over the past three decades, traumatic brain injury (TBI) has been considered a "silent epidemic" and recognized as an emergent public health problem by the Centers for Disease Control and Prevention (CDC). TBI is defined as a bump, blow, or jolt to the head that disrupts the normal function of the brain. Due to the debilitating effects and prevalence of TBI, novel preventative treatment regimens are highly desirable in at risk populations. According to the CDC groups disproportionately affected by TBI include athletes, people aged 75+, and service men and women, among others. Here, we investigated a unique whey protein …

Effects Of Yoga On Perceived Stress Level And Cognitive Ability In College-Aged Females, Rachel V. Taylor, Faith Flanders, Allison Esposito, Delaney Lister, Lauren Williams

The Corinthian

Purpose: The purpose of this study was to determine if perceived stress levels and response inhibition scores (measure of cognitive function) differ in female college students who regularly participate in yoga compared to female college students who do not.

Methods: College-aged females ranging from 19-24 years of age were recruited to participate in this study. Subjects filled out a personal information sheet followed by a perceived stress level questionnaire to measure the amount of yoga each participant performed and assess their perceived stress level, respectively. Response inhibition and accuracy (cognitive function) were measured via a computerized Stroop Effect test consisting …

Physiological And Behavioural Evaluation Of Common Anaesthesia Practices In The Rainbow Trout, Kieran C. Pounder, Jennifer L. Mitchell, Jack S. Thomson, Tom G. Pottinger, Lynne U. Sneddon

Anesthesia and Analgesia Collection

Anaesthetic drugs are commonly administered to fish in aquaculture, research and veterinary contexts. Anaesthesia causes temporary absence of consciousness and may reduce the stress and/or pain associated with handling and certain invasive procedures. The rainbow trout (Oncorhynchus mykiss) is a widely-used model species with relevance to both aquaculture and natural ecosystems. This study sought to establish the relative acute impact of commonly used anaesthetics on rainbow trout when used for anaesthesia or euthanasia by exploring their effects on aversion behaviour and stress physiology. Five widely used anaesthetics were investigated at two concentrations reflective of common laboratory practises: MS-222, benzocaine, 2-phenoxyethanol, …

Perception Of Emotional Valence In Horse Whinnies, Elodie Briefer, Roi Mandel, Anne-Laure Maigrot, Sabrina Briefer Freymond, Iris Bachmann, Edna Hillmann

Bioacoustics Collection

Background: Non-human animals often produce different types of vocalisations in negative and positive contexts (i.e. different valence), similar to humans, in which crying is associated with negative emotions and laughter is associated with positive ones. However, some types of vocalisations (e.g. contact calls, human speech) can be produced in both negative and positive contexts, and changes in valence are only accompanied by slight structural differences. Although such acoustically graded signals associated with opposite valence have been highlighted in some species, it is not known if conspecifics discriminate them, and if contagion of emotional valence occurs as a result. We tested …

Hemp: A Composition Review Plus, Agustin Gonzalo Miguel Garcia

Food Science and Nutrition

Hemp has been utilized by many societies around the world yet is currently absent in U.S. food production. The paper described and assessed various sources to aggregate hemp seed composition data and to decipher hemp seed consumption effect on health. There are copious components in hemp seeds that are discussed; some beneficial to human health as well as some anti-nutritional components that interfere. Numerous articles were analyzed and aspects of each were compiled to provide a source to assess the effectiveness of hemp seed as a nutritious source. Many components found in hemp seeds are found to be beneficial to …

College Of Pharmacy And Allied Health Professions, South Dakota State University

Jackrabbits Script and Scope (Formerly called College of Pharmacy and Allied Health Professions Magazine)

[Page] 2 A day in the life—The medical laboratory science program as seen through the eyes of second year student Brittany Kramer.
[Page] 4 What makes MLS special?—After being presented their white lab coats, medical laboratory science students share what drew them to the program.
[Page] 6 Meet the president—Allyson Helms, a P1 student from Waseca, Minnesota, is only the second pharmacy student to serve as president of the Students’ Association.
[Page] 8 Balance—Internationally known professor tells students about his professional achievements and discovering a work/life balance.
[Page] 10 Scholarship planning • Joye Ann Billow—Legacy of pioneering faculty member continues …

Blurred Lines: Emerging Practice For Registered Dietitian-Nutritionists In Integrative And Functional Nutrition, Patricia Grace-Farfaglia, Denise L. Pickett-Bernard, Andrea Gorman, Jaleh Dehpahlavan

Nutrition Sciences Faculty Publications

Background This study explored the health philosophy and practice orientation of RDNs in the United States. Methods A randomly selected group of RDNs were recruited to take an online survey using a reduced version of Integrative Medicine practice (IM-30). Confirmatory factor analysis, analyses of variance, and non-parametric tests were used to investigate the relationships between dietetic professionals' personal health philosophy, lifestyle, and orientation to Integrative Medicine. Results Overall construct validity of the IM-26 scale was demonstrated by Cronbach's α with reliabilities ranging from 0.766 to 0.89. Results from chi-square test of goodness-of-fit test (N = 477, χ2 = 228.72, p …

Ua61/1 Dnp Student Handbook, Wku School Of Nursing

WKU Administration Documents

Handbook for students in the DNP program of the WKU School of Nursing.

Do You Know If Your Clients Are Having Challenges Coping, Karen F. Muñoz, Hannah Mcleod, Cache Pitt, Elizabeth S. Preston, Tiffany Shelton, Michael P. Twohig

Communicative Disorders and Deaf Education Faculty Publications

Hearing loss is a common condition, yet, many adults who could benefit from amplification do not use their hearing aids, even though it could help them overcome negative consequences such as social withdrawal, loneliness, and depression. Equally concerning, hearing aid use is highly variable for young children, compromising speech and language developmental outcomes.

How clients are coping with emotional challenges may be a contributing factor to hearing aid usage, and such challenges may go undetected by audiologists. Depression and anxiety are common mental health conditions, and can interfere with effective healthcare management and treatment adherence; for example, when parents of …

Nurse Leaders' Response To Civil Unrest In The Urban Core, Roberta Lavin, Tener Veenema, Wilma Calvert, Sheila Grigsby, Jennifer Cobbina

Nursing Faculty Works

Inequalities in society, culture, and finance have resulted in civil unrest, rioting, and intentional violence throughout our history. Nowhere is this currently more apparent than in the cities of Ferguson and Baltimore. It is not the civil unrest itself, but the resulting rioting and intentional violence that can create a disaster situation. This increases the care burden of health care providers during times when the governmental structure may be overwhelmed or functioning in a less than optimal manner. Beginning with the death of Michael Brown, civil unrest over the last 2 years has necessitated a closer examination of the role …

An In Vitro Study Of The Interaction Of The Chemotherapeutic Drug Actinomycin D With Lung Cancer Cell Lines Using Raman Micro-Spectroscopy, Zeineb Farhane, Hugh Byrne, Franck Bonnier

Articles

The applications of Raman micro-spectroscopy have been extended in recent years into the field of clinical medicine, and specifically in cancer research, as anon-invasive diagnostic method in vivo and ex vivo, and the field of pharmaceutical development as a label free predictive technique for new drug mechanisms of action in vitro. To further illustrate its potential for such applications, it is important to establish its capability to fingerprint drug mechanisms of action and different cellular reactions. In this study, cytotoxicity assays were employed to establish the toxicity profiles for 48 and 72 hrs exposure of lung cancer cell lines, A549 …