Medicine and Health Sciences Commons^™

Astaxanthin Attenuates Mptp Induced Neurotoxicity And Modulates Cognitive Function In Aged Mice, Beth Grimmig

USF Tampa Graduate Theses and Dissertations

Parkinson’s disease is the second common neurodegenerative disease and is most frequently diagnosed in individuals over 60. There are no available medications that can prevent or restore the loss of neurons that correspond to motor impairments in patients. Identifying novel therapeutic compounds that are capable of slowing and reversing the extensive neurodegeneration that occurs in PD remains an important goal of the field. While basic research has identified potential therapeutic agents, studies often use young model organisms to demonstrate efficacy of the target compound. This approach ignores the impact of the aged CNS on the disease process, and likely contributes …

Santa Clara County Senior Nutrition Program Evaluation Report, Tae Hwan Ihm

Master's Projects

Santa Clara County conducts a Senior Nutrition Program (SNP) in conjunction with the City of San Jose, the Outreach Paratransit Program and local community-based organizations (CBOs) like Sourcewise (Lam, 2015). These programs combined represent a significant investment of public funds, with more than 45% of the SNP program’s funding coming from the county General Fund (Lam, 2015). Such a large financial commitment needs to demonstrate some benefit to the participants, and some positive outcomes from the current program design. This study evaluated the SNP’s effectiveness in achieving its primary goals. Primary goals of the SNP are to promote senior citizens’ …

The Age-Rage Axis In An Arab Population: The United Arab Emirates Healthy Futures (Uaehfs) Pilot Study, Claire K. Inman, Abdullah Aljunaibi, Hyunwook Koh, Abdishakur Abdulle, Raghib Ali, Abdullah Alnaeemi, Eiman Al Zaabi, Naima Oumeziane, Marina Al Bastaki, Mohammed Al-Houqani, Fatma Al-Maskari, Ayesha Al Dhaheri, Syed M. Shah, Laila Abdel Wareth, Wael Al Mahmeed, Habiba Alsafar, Fatme Al Anouti, Ayesha Al Hosani, Muna Haji, Divya Galani, Matthew J. O'Connor, Jiyoung Ahn, Tomas Kirchhoff, Scott Sherman, Richard B. Hayes, Huilin Li, Ravichandran Ramasamy, Ann Marie Schmidt

All Works

© 2017 The Authors Aims The transformation of the United Arab Emirates (UAE) from a semi-nomadic to a high income society has been accompanied by increasing rates of obesity and Type 2 diabetes mellitus. We examined if the AGE-RAGE (receptor for advanced glycation endproducts) axis is associated with obesity and diabetes mellitus in the pilot phase of the UAE Healthy Futures Study (UAEHFS). Methods 517 Emirati subjects were enrolled and plasma/serum levels of AGE, carboxy methyl lysine (CML)-AGE, soluble (s)RAGE and endogenous secretory (es)RAGE were measured along with weight, height, waist and hip circumference (WC/HC), blood pressure, HbA1c, Vitamin D …

Genetic Variation And Gene Expression Across Multiple Tissues And Developmental Stages In A Non-Human Primate, Anna J. Jasinska, Ivette Zelaya, Susan K. Service, Christine B. Peterson, Rita M. Cantor, Oi-Wa Choi, Joseph Deyoung, Eleazar Eskin, Lynn A. Fairbanks, John Blangero, Thomas D. Dyer

School of Medicine Publications

By analyzing multitissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman primate model. This catalog contains more genome-wide significant eQTLs per sample than comparable human resources and identifies sex- and age-related expression patterns. Findings include a master regulatory locus that likely has a role in immune function and a locus regulating hippocampal long noncoding RNAs (lncRNAs), whose expression correlates with hippocampal volume. This resource will facilitate genetic investigation of quantitative traits, including brain and behavioral …

A Suggested Plan For Specialist Doctor's Professional Growth And Development, Ahmed Nadeem Abbasi, Bilal Mazhar Qureshi

Department of Radiation Oncology

No abstract provided.

Development Of An Animal Model For Enterovirus For Evaluation D68 For Screening Of Antiviral Therapies, W. Joseph Evans

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Enterovirus D68 (EV-D68) virus has become more prevalent over the last 15 to 20 years. EV-D68 attacks the respiratory system and can cause severe disease in individuals who have underlying respiratory problems. There have also been reports of individuals with EV-D68 showing signs of neurological system problems and acute flaccid paralysis. Because of the increase in patients with EV-D68 and also the potential for neurological disease, an animal model is needed to study the disease and to evaluate experimental therapies for EV-D68 infection.

To develop the animal model, 4-week old AG129 mice that lack alpha and beta interferon receptors, making …

Surgical Approaches To Adenocarcinoma Of The Gastroesophageal Junction: The Siewert Ii Conundrum., Andrew M. Brown, Danica N. Giugliano, Adam C. Berger, Michael J. Pucci, Francesco Palazzo

Department of Surgery Faculty Papers

BACKGROUND: The Siewert classification system for gastroesophageal junction adenocarcinoma has provided morphological and topographical information to help guide surgical decision-making. Evidence has shown that Siewert I and III tumors are distinct entities with differing epidemiologic and histologic characteristics and distinct patterns of disease progression, requiring different treatment. Siewert II tumors share some of the characteristics of type I and III lesions, and the surgical approach is not universally agreed upon. Appropriate surgical options include transthoracic esophagogastrectomy, transhiatal esophagectomy, and transabdominal extended total gastrectomy.

PURPOSE: A review of the available evidence of the surgical management of Siewert II tumors is presented. …

The Effects Of Family Stressors On Depression In Latino Adolescents As Mediated By Interparental Conflict, Jenny Carolina Mondragon

Theses and Dissertations

Extensive literature suggests that Latino youth experience higher levels of depression when compared to youth from other ethnic backgrounds yet relatively little is known regarding why this particular population is especially susceptible to depression. This study focused on family level stressors and the link between interparental conflict and adolescent depressive symptoms in Latino families. The sample consisted of 400 girls and 290 boys, they were distributed into four groups based on gender and family structure. Written surveys were completed in their respective English classes measuring the aforementioned variables. Results indicated a significant relationship across all four groups between family stressors …

Plasmodium Falciparum Parasites With Histidine-Rich Protein 2 (Pfhrp2) And Pfhrp3 Gene Deletions In Two Endemic Regions Of Kenya, Khalid B. Beshir, Nuno Sepúlveda, Jameel Bharmal, Ailie Robinson, Julian Mwanguzi, Annette Obukosia Busula, Jetske Gudrun De Boer, Colin Sutherland, Jane Cunningham, Heidi Hopkins

All Peer-Reviewed Publications

Deletions of the Plasmodium falciparum hrp2 and hrp3 genes can affect the performance of HRP2-based malaria rapid diagnostic tests (RDTs). Such deletions have been reported from South America, India and Eritrea. Whether these parasites are widespread in East Africa is unknown. A total of 274 samples from asymptomatic children in Mbita, western Kenya, and 61 genomic data from Kilifi, eastern Kenya, were available for analysis. PCR-confirmed samples were investigated for the presence of pfhrp2 and pfhrp3 genes. In samples with evidence of deletion, parasite presence was confirmed by amplifying three independent genes. We failed to amplify pfhrp2 from 25 of …

The Impact Of A Nurse-Driven Foley Catheter Removal Protocol On Catheter Associated Urinary Tract Rates In Critical Care Areas, Laura Eckert-Davis

Nursing Masters

Background: Indwelling urinary catheters serve a purpose in critical care; however, they can also pose a risk for patients. With increased catheter use, there is an increased risk of developing a catheter associated urinary tract infection (CAUTI). CAUTIs lead to longer length of stay for patients, antibiotic treatment, and have a financial burden to the institution. The objective of this study was to determine if a nurse driven catheter removal protocol could reduce CAUTIs in critical care units.

Methods: Retrospective review of CAUTI data from the National Healthcare Safety Network (NHSN) was observed three months prior to the protocol implementation …

Organ Donation Education And Its Effects On Undergraduate Nursing Students' Knowledge And Perceptions, Jessica D'Acquisto

Nursing Masters

Abstract

Introduction: America continually struggles with a shortage of registered organ donors and a constant need of organs. To address this, future nurses should be taught about the need for organ donation in their studies, so that as nurses, they can help increase the number of registered organ donors in the country by educating patients about the value of organ donation.

Objective: To evaluate the effects of an educational intervention on undergraduate nursing students’ knowledge, perceptions, and the potential of them registering as organ donors.

Methods: Twenty eight undergraduate nursing students from a private college in central New York participated …

Assessing Healthcare Providers Perspective: Music Intervention For Open Heart Surgery Patients, Karsen Lattimore

Nursing Masters

Abstract

Background: Benefits of music intervention after open heart surgery have been studied amongst several clinical settings, yet implementation is not frequently seen with patients in the cardiothoracic field. Open heart surgery is associated with postoperative pain that peaks the first few days after surgery. Multiple negative outcomes may result from ineffective pain management including, deep vein thrombosis, pneumonia, and poor wound healing leading to increased morbidity, mortality, and healthcare costs. Music intervention has been shown to relieve anxiety and pain, reduce stress, decrease S-cortisol levels and increase oxytocin levels. However, the literature is limited on the use or integration …

Enhanced Recovery After Pancreatic Surgery, Yeliam Patel

Nursing Masters

Abstract

Background: Enhanced Recovery After Surgery (ERAS) protocols are evidence-based multimodal pathways that optimize the perioperative care of patients undergoing complex surgeries. The goal is to promote acute recovery as demonstrated by decreased length of stay (LOS) with no negative impact on the complication or readmission incidence. There is limited adoption of ERAS protocols for major pancreatic surgeries such as pancreaticoduodenectomy (i.e., Whipple surgery).

Objectives: The primary aim of this study was to evaluate if outcomes such as LOS, readmission (within 30 days of initial hospitalization), and complication occurrence were improved after the application of the ERAS protocol in …

Pediatric Burn Prevention: Determining Provider Knowledge Of Pediatric Burn Epidemiology And Prevalence Of Education At Well Child Visits., Elizabeth Blasi

Nursing Masters

Objective: Pediatric burns are costly and traumatic injuries; however, increased education may reduce the prevalence. The purpose of this study was to determine pediatric primary care providers’ awareness of the pervasiveness of pediatric burns and discern if specific education is done at office visits. Methods: Eighteen providers participated in an education session regarding pediatric burns and took a pre-test and post-test. Results were analyzed to determine if the education led to an increase in provider knowledge of burns as well as in increase in motivation to educate their patients. Results: The education session led to an increased awareness of burn …

The Development, Implementation And Evaluation Of An Educational Program For Staff Nurses To Identify And Manage Risk Factors For Ischemic Stroke In Patients With A History Of Migraine, Scottia Jones

Nursing Masters

The literature findings demonstrate that patients with migraines have a significantly high incidence of ischemic stroke (Kurth, 2010). Migraine is a common neurological disease that is defined very poorly and is estimated to affect between 1 % and 10% of men and 3 % and 20% of women within the United States (Buring & Hennekens 1995). Decreasing migraine frequency and management of modifiable stroke and cardiovascular risk factors'-, such as hypertension, high cholesterol and smoking can help decrease risk of stroke occurrences (Tietjen, 2005). Therefore, to decrease stroke occurrence, it is imperative that staff nurses are educated on the importance …

Contributors To Wisconsin’S Persistent Black-White Gap In Life Expectancy, Max T. Roberts

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

For decades, blacks have faced shorter life expectancy than their white counterparts. This persistent disparity has led to a gap in life expectancy between the two groups. Nationally, this gap has decreased over the last 40 years. However, this is not the case at the state-level as some states have experienced little or no improvement in the life expectancy gap. Such is the case in Wisconsin, where the life expectancy gap is the largest in the nation for males, and the gap actually has grown for females over the last two decades. This study seeks to examine this persistent gap …

Negative Predictive Value Of Ultrasound In Predicting Tumor-Free Margins In Specimen Sonography, Saira Naz, Saima Hafeez,, Zainab Hussain, Kiran Hilal

Department of Radiology

OBJECTIVE: To evaluate the success of ultrasound in post-excision specimen visualization, and negative predictive value of ultrasound for estimation of tumor-free margins using histopathology as the gold standard.

STUDY DESIGN: Cross-sectional analytical study.

PLACE AND DURATION OF STUDY: The Aga Khan University Hospital, Karachi, Pakistan, from May 2010 till January 2013.

METHODOLOGY:

Sonography of all breast nodules was done before and after exicision by two female radiologists with at least five years clinical experience. All surgeries were performed by the same referring breast surgeons. All nodules were non-palpable and had histopathology as well as specimen sonography performed at AKUH. …

Primary Headache Disorders In The Adult General Population Of Pakistan – A Cross Sectional Nationwide Prevalence Survey, Herekar Aa, Ahmad A, Uqaili Ul, Ahmed B, Effendi J, Alvi Sz, Shahab Ma, Javed U, Herekar Ad, Khanani R, Steiner Tj

Section of Neurology

Back Ground: The large geographical gaps in our knowledge of the prevalence and burden of headache disorders include almost all of Eastern Mediterranean Region (EMR). We report a nationwide population-based study in Pakistan, an EMR country with the sixth largest population in the world, conducted as a project within the Global Campaign against Headache.

Methods: We surveyed six locations from the four provinces of Pakistan: Punjab, Sindh, Khyber Pakhtunkhwa and Baluchistan. We randomly selected and visited rural and urban households in each. One adult member (18-65 years) of each household, also randomly selected, was interviewed by a trained non-medical interviewer …

Examining The Human Infectious Reservoir For Plasmodium Falciparum Malaria In Areas Of Differing Transmission Intensity, Bronner P. Gonçalves, Melissa C. Kapulu, Patrick Sawa, Wamdaogo M. Guelbéogo, Alfred B. Tiono, Lynn Grignard, Will Stone, Joel Hellewell, Kjerstin Lanke, Guido J.H. Bastiaens, John Bradley, Issa Nébié, Joyce M. Ngoi, Robin Oriango, Dora Mkabili, Maureen Nyaurah, Janet Midega, Dyann F. Wirth, Kevin Marsh, Thomas S. Churcher, Philip Bejon, Sodiomon B. Sirima, Chris Drakeley, Teun Bousema

All Peer-Reviewed Publications

A detailed understanding of the human infectious reservoir is essential for improving malaria transmission-reducing interventions. Here we report a multi-regional assessment of population-wide malaria transmission potential based on 1209 mosquito feeding assays in endemic areas of Burkina Faso and Kenya. Across both sites, we identified 39 infectious individuals. In high endemicity settings, infectious individuals were identifiable by research-grade microscopy (92.6%; 25/27), whilst one of three infectious individuals in the lowest endemicity setting was detected by molecular techniques alone. The percentages of infected mosquitoes in the different surveys ranged from 0.05 (4/7716) to 1.6% (121/7749), and correlate positively with transmission intensity. …

Parenting Stress And Emotion Dysregulation In Children With Dd: The Role Of Parenting Behaviors, Neilson Chan

Loma Linda University Electronic Theses, Dissertations & Projects

Parents of children with developmental delays (DD) report higher levels of parenting stress compared to parents of typically developing children. High levels of parenting stress have been associated with negative outcomes for their children, including higher levels of emotion dysregulation. However, this relationship between parenting stress and child emotion dysregulation has rarely been examined in families of children with DD. Additionally, the mechanisms through which parenting stress influences child emotion dysregulation remain unclear; it may be that parenting stress impacts parenting behaviors (i.e., sensitive and intrusive parenting), which in turn influence the development of the child’s emotion regulatory abilities. In …

Outbreak Response And Incident Management: Shea Guidance And Resources For Healthcare Epidemiologists In United States Acute-Care Hospitals., David B Banach, B Lynn Johnston, Duha Al-Zubeidi, Allison H Bartlett, Susan Casey Bleasdale, Valerie M Deloney, Kyle B Enfield, Judith A Guzman-Cottrill, Christopher Lowe, Luis Ostrosky-Zeichner, Kyle J Popovich, Payal K Patel, Karen Ravin, Theresa Rowe, Erica S Shenoy, Scott Stienecker Md, Pritish K Tosh, Kavita K Trivedi

Hospital Medicine

This expert guidance document was developed as a resource to provide healthcare epidemiologists working in acute-care hospitals with a high-level overview of incident management for infectious diseases outbreaks and to prepare them to work within an emergency response framework. It addresses how the epidemiologist’s skills and expertise apply to scenarios that require enhanced preparedness and response efforts, eg, when pathogens associated with outbreaks are poorly characterized or when outbreaks require additional interventions including, but not limited to, healthcare personnel education, enhanced infection prevention and control measures, added staffing, supplies, and resources, adjustments to clinical and support activities, and external communications. …

Evaluation Of Genetic Polymorphism, Genomic Template Stability, Condition Factor And Hemato-Biochemical Parameters In Response To Slow Reduction In Water Level During Nile Tilapia (Oreochromis Niloticus) Harvest, Radi A. Mohamed, Aziza A. Aboulila, Sherif Z. El-Kholya, Ahmed Hamza

The Thai Journal of Veterinary Medicine

The aim of this study was to evaluate the effect of slow reduction in water level during Nile tilapia (Oreochromis niloticus) harvest on growth performance, condition factor, hemato-biochemical parameters, genetic polymorphism, and genomic template stability. During tilapia harvest, water level was reduced from 150 to 30 cm in different duration as follows: group one (control), in 72 hours (h); group two, in 48 h; and group three, in 24 h. There was a significant correlation between length and weight of fish among all experimental groups. Condition factor showed significant differences (P˂0.05) among all experimental groups. Hemato-biochemical parameters showed no significant …

Re-Estimation Of Supplemented Methionine As Total Sulfur Amino Acid Requirement For Commercial Male Meat-Type Ducks, Kriengkrai Prahkarnkaeo, Kiattawee Choowongkomon, Boonorm Chomtee, Choawit Rakangthong, Chaiyapoom Bunchasak

The Thai Journal of Veterinary Medicine

The total sulfur amino acid (TSAA) requirements of commercial meat-type ducks were investigated by feeding diets supplemented with graded levels of DL-methionine (DL-met) compared with the standard recommendation for the strain during 3 growth phases. Five hundred male White Pekin ducklings were divided into 4 treatments, each of which consisted of 5 replicates (25 each) using a completely randomized design. From the birds aged 1-9 and 10-16 days, TSAA deficit diet significantly depressed growth rate and feed intake (P<0.05). During 10-16 days of age, the growth rate of the birds fed TSAA at 110% of the commercial requirement was faster than that of the 100% group, with the increase in growth rate and feed intake paralleling the TSAA intake (P<0.01). No significant effects of the TSAA level on productive performance of the birds from age 17-47 days were found. At the age of 47 days, increasing the TSAA levels up to 120% tended to decrease abdominal fat content (P=0.08), and significantly decreased blood uric acid concentration (P<0.01). There were no significant differences in carcass components and lipid profile in the serum. The TSAA level for optimum growth rate and FCR in commercial meat-type ducks is 100-110% of the recommended level for the strain, except during 10-16 days of age when 110% is recommended.

Short-Term Effect Of Coconut Oil Supplementation On Meal Pattern In Crossbred Dairy Goats Fed Under Tropical Environment, Sumpun Thammacharoen, Thiet Nguyen, Somchai Chanpongsang, Narongsak Chaiyabutr

The Thai Journal of Veterinary Medicine

Eating behavior is influenced by various external stimuli, including food and ambient temperature (Ta). In dairy animals, high ambient temperature (HTa) decreases eating and subsequently reduces milk production. Eight crossbred non-lactating Saanen goats in late pregnancy fed under HTa condition were used to investigate the normal eating behavior by comparing the short-term eating pattern of control with 2% coconut oil supplemented formulations. The goats were fed ad libitum twice daily a total mix ration with free access to water. The experiment lasted 17 days, 9 days for adaptation and 8 days for data collection. Meal patterns were determined on the …

Investigation Into Antimicrobial Resistance, Enterotoxin And Cassette Chromosome Gene Of Staphylococcus Aureus Isolates From Humans, Cows And Goats In Taiwan, Chi-Shih Chu, Han Hsiang Huang, Shou-Heng Chiang, Chi-Chung Chou, Jyh-Mirn Lai, Wen-Ling Shih, Chih-Hsuan Changchien, Heng-Ching Lin, Shih-Te Chuang, Yao-Chi Su

The Thai Journal of Veterinary Medicine

Multidrug-resistant Staphylococcus aureus (MDR S. aureus) is predominately present in humans and animals. Staphylococcal enterotoxin (SE) is one of the representative toxins produced by S. aureus. The drug resistance patterns, presence of eighteen SE genes and staphylococcal cassette chromosome (SCCmec) in S. aureus strains isolated from human cellulitis, septicemia, mastitis and farmed ruminant mastitis were investigated and analyzed. Methicillin-resistant S. aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) accounted for 51.35% (76/148) and 48.65% (72/148), respectively. Both MSSA and MRSA carried sea (15%), seb (30.8%) and sek (27.5%) genes. Eighty percent of the MRSA strains (52/65) belonged to SCCmec types I, …

Investigation Into The Effect Of Prostaglandin F2a, Gnrh Analogue And Hcg On Induction Of Ovulation In Mares, Kanittha Phetudomsinsuk

The Thai Journal of Veterinary Medicine

In order to prove the effect of “fixed time service”, this study aimed to determine reproductive efficiency of hormone manipulation to induce ovulation and improve pregnancy rate. Estrus cycles of fifty mares were monitored every other day until ovulation by ultrasound (control group). Six days after ovulation, all mares received 5 mg prostaglandin F2a in order to synchronize estrus cycle. Reproductive tract monitoring was continued until the follicle reached the size of 35 mm and uterine edema was scored 2. Then, the mares were randomly assigned into four groups and treated with different ovulation stimulation methods: T1, spontaneous ovulation (n=10); …

Effects Of Induced Subacute Ruminal Acidosis And Laminitis On Lipopolysaccharide Binding Protein, Cortisol And Progesterone Levels In Dairy Heifers, Suvaluk Seesupa, Chalong Wachirapakorn, Suneerat Aiumlamai

The Thai Journal of Veterinary Medicine

Subacute ruminal acidosis (SARA) is a predisposing cause of laminitis and results in an inflammatory response in dairy cattle. However, the link between SARA associated with laminitis and inflammation and the endocrinal profiles related to reproduction has not been clearly demonstrated. This study was conducted to investigate the effects of high concentrate-induced SARA and laminitis on the changes in lipopolysaccharide binding protein (LBP), cortisol and progesterone in dairy heifers. Six treated heifers were induced by feeding concentrate ad libitum with restricted amounts of rice straw (1 kg DM/day), while six control heifers were restrictively fed amounts of concentrate (2.2 kg …

Effect Of A Mixture Of Essential Oils And A Plant-Based Extract For The Management Of Localized Superficial Pyoderma In Dogs: An Open-Label Clinical Trial, Lerpen Duangkaew, Lawan Larsuprom, Chalermpol Lekcharoensuk, Charles Chen

The Thai Journal of Veterinary Medicine

A mixture of essential oils and a plant-based extract in the form of shampoo and spot-on were shown to have in vitro antimicrobial activity against Staphylococcus pseudintermedius. The purpose of this open-label clinical trial was to evaluate the efficacy of these two products for the management of canine localized superficial pyoderma. Twenty dogs diagnosed with 3-4 localized pyoderma lesions were enrolled. The dogs were bathed weekly for 8 weeks with shampoo and 48 hours later, spot-on was applied near the lesions. Clinical lesions and pruritus scores were subjectively assessed using a clinical improvement score system (1-5) and a pruritic visual …

Effects Of Monosodium Glutamate On Heart Beat And The Embryonic Development Of Zebrafish, Naowarat Suthamnatpong, Aranya Ponpornpisit

The Thai Journal of Veterinary Medicine

The effect of monosodium glutamate (MSG) on zebrafish, Danio rerio, embryo was investigated at different concentrations of ten-fold dilution of ten times lesser than the median lethal concentration (LC50). Zebrafish embryos in the MSG treated groups (40,000 ppm and 80,000 ppm) reached highest mortality rate at 100 % within 48 hpf and 96 hpf which is significantly different (p<0.05) from negative control group. According to the Probit analysis, the LC50 of MSG on zebrafish embryo at 48 hpf and 96 hpf were 15,200 ppm and 10,300 ppm, respectively. Under the observation, effects based on the toxicity endpoint composed of lethal, sublethal and malformation effects appeared within 144 hpf. Exposure to MSG at 1,500 ppm and 150 ppm significantly produced sublethal effects and malformation development to zebrafish embryo. MSG induced cardiotoxic effects in zebrafish embryo was observed at 15, 150 and 1,500 ppm. Our results demonstrate that zebra fish embryo is a good model for the detection of toxic potential of chemical substances. Also, our data suggest the need to reconsider the safety of MSG and elucidate its mechanism of adverse reaction in further studies.

Treatment Of Cloacal Papilloma With 50% Silver Nitrate Solution In Chestnut-Fronted Macaws (Ara Severus), Thawat Lekdumrongsak, Wijit Banlunara

The Thai Journal of Veterinary Medicine

Cloacal papilloma is commonly found in Amazon parrots and macaws. There are many treatment options for cloacal papilloma. Chemical cautery is one of the recommended methods. In this study, 6 mature chestnut-fronted macaws (Ara severus) with cloacal papilloma were treated weekly with 50% silver nitrate solution. All tumors completely regressed after 2 to 5 weeks of treatment. One bird died after the second treatment from another cause. Three months after the last treatment, one bird died from internal papilloma in the esophagus and the crop. Recurrence was found in one bird at 6 months after the last treatment. The result …