Medicine and Health Sciences Commons^™

The Effects Of Spondylolisthesis On The Human Body, Kayla L. Govoni

Senior Honors Projects

Spondylolisthesis is a rare and unknown disorder to many. The anatomical perplexity beneath its diagnosis is extensive yet crucial to truly understanding this unique anomaly. As a condition that is too often undistinguished and unexplained to countless, it warrants and demands undisputed attention. Spondylolisthesis is an atypical spinal disorder characterized by one vertebra sliding forward in position over the vertebra below it (Rodts, 2017). The victim of this condition faces excruciating pain radiating throughout one’s lower back and frequently into the lower extremities. In cases of increased severity, individuals pursue a variety of treatment modalities ranging from conservative measures such …

Bilingualism And The American Family, Caitlin M. Nickerson

Senior Honors Projects

Bilingualism is the ability to speak more than one language fluently. People of all ages may aspire to learn a second or third language in order to fulfill both personal goals and communicate with a variety of people in different contexts. Irrespective of one’s walk of life or socioeconomic status, being bilingual is a valuable skill. Although English is the language of power in the United States, there are hundreds of other languages spoken in this country.

There are a number of different ways in which children can become bilingual. For example, they may enter the school system speaking the …

Determining The Effects Of Social Media Monitoring To Identify Potential Foodborne Illness In Southern Nevada, Lauren Diprete

UNLV Theses, Dissertations, Professional Papers, and Capstones

Foodborne illness, commonly referred to as food poisoning, affects an estimated 1 in 6 Americans every year, despite the fact that it is entirely preventable. Many cases of foodborne illness go unreported; however, better reporting leads to faster health department response and containment. Social media monitoring, using software to identify trends in social media posts, is a novel new tool that has been tested in a variety of public health fields with promising preliminary results. The Southern Nevada Health District (SNHD) has employed social media monitoring software to identify potential foodborne illness within Southern Nevada. The purpose of this study …

Knowledge And Awareness Regarding Cervical Cancer And Uptake Of Pap Smear Among Women In Karachi, Pakistan, Shama Razzaq, Sayeeda Amber Sayed Amber Sayeeda Amber Sayed, Sumera Aziz Ali

Community Health Sciences

Objective: To determine the knowledge regarding cervical cancer, its symptoms and risk factors among women of 18 years and above attending the gynecology OPD in two public hospitals Karachi, Pakistan.
Methodology: A cross-sectional survey was held from February to June 2013 in Karachi, Pakistan. 384 females aged 18 years and above attending gynecology clinics in two public sector hospitals were taken through non-probability sampling method. The knowledge was assessed using a point scale method which had binary response i.e. correct and incorrect. A score of 50% (≥ 11 correct responses) was considered as optimum knowledge.
Results: Overall knowledge of cervical …

Physico-Chemical And Microbiological Quality Changes In Cocoa And Whey Protein Enriched Functional Dairy Drink During Storage, H. R. Gupta, S. K. Kanawjia, M. K. Salooja, Prateek Sharma, Anil Kumar

Nutrition, Dietetics, and Food Sciences Faculty Publications

Cocoa and whey protein enriched functional dairy drink was subjected to storage studies at refrigeration temperature 4±1°C in the present study. The samples were studied for microbial and physicochemical tests during storage. The results in this study suggest that the product can be stored upto 18 days at 4±1°C. A decrease in pH from 7.01 to 6.49 for whey protein enriched product and from 6.94 to 6.41 in case of cocoa & whey protein enriched product was observed at the end of shelf life. The FFA increased from 0.72 to 1.46 meq./ml at the end of shelf life of 18 …

Development Of Culture-Centered Diabetes Education Program For Nigerian Immigrants, Gloria Ozioma Ibezim

Nursing Masters

Purpose: This study aimed to develop a culture-centered diabetes education program (CCDEP) for Nigerian immigrants to assess knowledge and attitudes on Diabetes Mellitus (DM).

Design: A descriptive pretest-posttest interventional study was deployed that used Microsoft Excel Analysis. There were 40 participants from a convenience sample from Western New York who received an hour CCDEP that instructed them on culture-centered DM care: tailored context, healthy dietary substitutes, stress management, and physical activities. A pretest measured the participants’ baseline knowledge and attitudes, and a posttest was given after the intervention.

Results: Participants demonstrated more knowledge on DM in the …

Interdisciplinary Team Based Pastoral Care: A Potentially Adaptable Model For Estonian Healthcare, Liidia Meel, Tõnu Lehtsaar

Occasional Papers on Religion in Eastern Europe

This article aims to build a potentially adaptable model of clinical pastoral care for Estonia’s healthcare institutions. To help the development of spiritual support provision in Estonian healthcare institutions, we are currently working on creating a model of clinical pastoral care that would be in accordance with the local circumstances. Preparatory research in the matter has addressed the socio-cultural and institutional context that shows the great need for interdisciplinary teamwork. The current article offers concrete proposals in the following main points: a) presentation of the pastoral caregiver; b) main actors; c) forms of cooperation; and c) education and internal trainings. …

Comparative Evaluation Of The Antibacterial, Anti-Biofilm And Anti-Spore Effects Of Theaflavins And Palmitoyl-Egcg, Gabriella M. Appice

Seton Hall University Dissertations and Theses (ETDs)

Tea, one of the most common beverages, originates from the leaves of the Camellia sinensis plant. Two major groups of tea are fermented black tea and unfermented green tea. Theaflavins (TFs) are the major polyphenols present in black tea, while mono-palmitoyl-epigallocatechin-gallate (pEGCG) is a modified green tea polyphenol. In this study, the antibacterial effects of TF and pEGCG were evaluated against six selected bacteria, Staphylococcus epidermidis, Streptococcus mutans, Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris, using an antibacterial assay. A viability assay using SYTOX® staining and flow cytometry was also used to determine the effect of these compounds …

Eliminating Wrong Blood Transfusions - Recent Advances, Farheen Karim, Salman Naseem Adil

Department of Pathology and Laboratory Medicine

No abstract provided.

Adaptation Of The Recent Life Changes Questionnaire (Rlcq) To Measure Stressful Life Events In Adults Residing In An Urban Megapolis In Pakistan, Azmina Artani, Shireen Shehzad, Iqbal Azam Syed, Moiz Abdul Sultan, Adeel Khoja, Ayeesha Kamran Kamal

Section of Neurology

Background: Contextually relevant stressful life events are integral to the quantification of stress. None such measures have been adapted for the Pakistani population.

Methods: The RLCQ developed by Richard Rahe measures stress of an individual through recording the experience of life changing events. We used qualitative methodology in order to identify contextually relevant stressors in an open ended format, using serial in-depth interviews until thematic saturation of reported stressful life events was achieved. In our next phase of adaptation, our objective was to scale each item on the questionnaire, so as to weigh each of these identified events, in terms …

Case Series Of Rare Interstitial Lung Disease (Ild)., Naveed Haroon Rashid, Saba Farooq, Mohammad Ahmed, Ali Bin Sarwar Zubairi

Department of Medicine

Pulmonary alveolar proteinosis (PAP) is a rare lung disease where periodic acid Schiff (PAS)-positive eosinophilic material accumulates in the alveoli of the lungs. Here we describe two cases of young males who presented with dynpnoea and weight loss. The HRCT scan of the chest in both cases showed the typical "crazy-paving" pattern and lung biopsies confirmed the diagnosis of PAP. They showed remarkable symptomatic improvement with therapeutic whole lung lavage.

Dox Inducible Idh2 R140q Expression In Stem Cells Results In Cell Death, Opposite Of Cancerous Overgrowth, Reuben Hogan

Undergraduate Research Symposium Posters

Mutations in isocitrate dehydrogenase (IDH) 1 or 2 are found in about 23% of acute myeloid leukemia (AML) samples and about 90% of gliomas. Mutations result in neomorphic function of the IDH enzyme that yields the novel molecule 2-hydroxyglutarate (2HG) instead of alpha-ketoglutarate (aKG). 2HG is known to be associated with hypermethylation of DNA and histones, a phenotype seen in AML. Our lab intends to study the mechanism by which hypermethylation is achieved and how this mechanism relates to the onset of cancer. In this experiment, we utilized a line of H9 stem cells which we had developed. These cells …

Fibulin-4 Is Essential For Maintaining Arterial Wall Integrity In Conduit But Not Muscular Arteries., Carmen M. Halabi, Thomas J. Broekelmann, Michelle Lin, Vivian S. Lee, Mon-Li Chu, Robert P. Mecham

Department of Dermatology and Cutaneous Biology Faculty Papers

Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial tortuosity, and aortic aneurysms. We sought to determine the consequences of a human disease-causing mutation in FBLN4 (E57K) on the cardiovascular system and vascular elastic fibers in a mouse model of ARCL1B. Fbln4^E57K/E57K mice were hypertensive and developed arterial elongation, tortuosity, and ascending aortic aneurysms. Smooth muscle cell organization within the arterial wall of large conducting vessels was abnormal, and elastic fibers were fragmented and had a moth-eaten appearance. …

Multidisciplinary Approach To The Prenatal Diagnosis And Post Natal Management Of A Large Suprasellar Arachnoid Cyst: A Case Report, Omar Irfan, Heera Nand Rathore, Sarfraz Karim, Shabina Ariff, Aneela Darbar

Medical College Documents

Arachnoid cysts are intra-arachnoid sacs filled with cerebrospinal fluid representing a rare occurence in neonates. We report the case of a suprasellar arachnoid cyst diagnosed prenatally at 21 weeks gestation on routine obstetric ultrasound. A cystic lesion was picked up incidentally at routine antenatal scan. The cyst was noted to be increasing in size over a series of radiological scans. The cyst was diagnosed as a suprasellar arachnoid cyst compressing the third ventricle and bilateral lateral ventricles. A left pteryonal craniotomy for cystocisternostomy of large suprasellar cyst was performed initially. Within a month the cyst recurred with clinical and radiological …

Hyper Ige Syndrome And Renal Cell Carcinoma, N Patel, Mark J. Ferretti, John L. Phillips

NYMC Faculty Publications

Hyper IgE Syndrome (HIES) is an immunodeficiency disorder characterized by increased serum levels of IgE, eczema, and recurrent cutaneous and pulmonary infections. In this report, we present, to our knowledge, the first documented case of renal cell carcinoma (RCC) found in a patient with HIES. The patient received infectious disease clearance prior to obtaining a partial nephrectomy which revealed clear cell histology. Both HIES and RCC have an immunological basis for their pathophysiology and may involve common pathways. Further studies may provide insight into any possible link and clinicians should be mindful of immunocompromised patients who present with risk factors …

Annual Wormwood Leaf Inhibits The Adipogenesis Of 3t3-L1 And Obesity In High-Fat Diet-Induced Obese Rats, Y Song, S Lee, S Jang, T Kim, Hong-Duck Kim, S Kim, C Won, J Cho

NYMC Faculty Publications

Annual wormwood (AW) (Artemisia annua L.) has anti-malarial, anti-bacterial, anti-oxidant, anti-tumour, and anti-inflammatory activities. In the present study, we evaluated the effects of annual wormwood leaves (AWL) on adipocyte differentiation in 3T3-L1 cells and high-fat diet (HFD)-induced obese rats. 3T3-L1 adipocytes and HFD-induced obese rats were treated with AWL, and its effect on gene expression was analyzed using RT-PCR and Western blotting experiments. Treatment with AWL effectively prevented triglyceride accumulation during adipogenesis in a dose-dependent manner. Consistently, AWL suppressed the differentiation of 3T3-L1 preadipocytes into adipocytes through the downregulation of dexamethasone, 3-isobutyl-1- methylxanthine, and insulin (DMI)-induced serine/threonine kinase protein kinase …

Impact Of Sleep Apnea On In-Hospital Outcomes After Transcatheter Aortic Valve Replacement: Insight From National Inpatient Sample Database 2011-2014, I Yeo, Hasan Ahmad, Wilbert Aronow

NYMC Faculty Publications

BACKGROUND: Sleep apnea is associated with worse outcomes following various kinds of surgeries. There is a paucity of data on the association of sleep apnea with clinical outcomes after transcatheter aortic valve replacement (TAVR). METHODS: We used National Inpatient Sample (NIS) data 2011-2014 to identify patients undergoing TAVR. Association between sleep apnea and in-hospital postoperative outcomes were assessed by multivariate logistic regression and 1:1 propensity score matching analyses. RESULTS: Of 42,189 patients who received TAVR, 4,605 patients (10.9%) had sleep apnea. Patients with sleep apnea were more likely to be younger and male with higher prevalences of hypertension, diabetes mellitus, …

Mental Health Counselors Working With Individuals With Developmental Disabilities: A Phenomenological Investigation, Syard G. Evans

Graduate Theses and Dissertations

Individuals with intellectual and developmental disabilities are often not included in traditional mental health treatment services due to beliefs that these individuals cannot benefit from mental health counseling and that mental health clinicians are not capable of treating this population. Some research exists that discusses techniques and interventions recommended to serve individuals with intellectual and developmental disabilities in mental health; however, there is little information on the specific counselors who are willing and able to support this population. A qualitative methodology was utilized to examine the phenomenon of mental health practitioners with experience serving individuals with intellectual and developmental disabilities. …

Sensitivity Of Diffuse Reflectance Spectroscopy To Dose- And Depth-Dependent Changes In Tumor Oxygenation After Radiation Therapy, Daria Semeniak

Graduate Theses and Dissertations

Along with chemotherapy, immunotherapy, and surgery, radiotherapy is one of the most common treatments used against cancer. Around 50% of all cancer patients undergo radiation therapy. While for some patients radiotherapy works efficiently and lead to a complete cancer disappearance, for others treatment outcome may be less favorable due to radioresistance processes happening within a tumor on the molecular level. Radioresistance remains a big challenge for modern oncology. The ability to identify radioresistance at the early stage of radiotherapy would help physicians to improve therapy efficiency. At the current moment, despite the rapid progress in cancer understanding and diagnostic modalities, …

Sex Differences In Μ-Opioid Receptor Regulation Of The Rat Locus Coeruleus And Their Cognitive Consequences, Herminio M. Guajardo, Kevin Snyder, Andrew Ho, Rita J. Valentino

Health & Biomedical Sciences Faculty Publications

Stress-related neuropsychiatric pathologies are more prevalent in females compared with males. An important component of the stress response is activation of the locus coeruleus (LC)-norepinephrine system. Because LC activation is tempered by endogenous opioid release during stress, the magnitude of opioid regulation of the LC could determine stress vulnerability. Here we report convergent evidence for decreased μ-opioid receptor (MOR) function in the female rat LC. The selective MOR agonist, DAMGO (10 pg), completely inhibited LC discharge of male but not female rats and DAMGO (30 pg) produced no further inhibition of female LC neurons. Consistent with a decreased maximum DAMGO …

Implementation Of Ventilator Bundle In Pediatric Intensive Care Unit Of A Developing Country, Anwar Ul Haque, Quratulain Riaz, Syed Asad Ali

Department of Paediatrics and Child Health

The aim of this study was to assess the frequency of VAP(ventilator associated pneumonia) after strict implementation of ventilator bundle in PICU. Medical records of all children (age 1 month - 16 years) were retrospectively reviewed, who were on mechanical ventilation (MV) for more than 48 hours and received all key components of "ventilator bundle" from January 2012 to December 2014. Out of 1050, 565 (54%) patients were enrolled. The mean age was 4.02 SD 4.29 years and 62 (69%) were male. The indications of MV were respiratory illness (54%), neurological illness (31%), shock (9%), and postoperative care (6%). The …

Concurrent Surgery And Informed Consent, Andrew M. Weller

College Honors Program

This thesis seeks to construct an ethical course of action for concurrent surgery, a practice brought into the public eye by The Boston Globe, which argued against allowing one attending surgeon to oversee two cases on separate patients in different operating rooms. First, the common morality and its four main principles relevant to biomedical ethics will be described which will be subsequently used to show that concurrent surgery is allowed according to non-violation of the principle of non-maleficence through current empirical evidence, and supported by the principle of beneficence and justice. Next, the principle of respect for autonomy will be …

The Msaabcr Operon Mutant Staphylococcus Aureus Is Deficient In Persister Cells, Aaliyah D. Cole

Honors Theses

Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in chronic infections. While this phenomenon has posed a great threat in public health, mechanism underlying their formation in Staphylococcus aureus remains largely unknown. Increasing evidence of the presence of persister cells in recalcitrant infections underscores the great urgency to unravel the mechanism by which these cells are developed. The Elasri Research group characterized msaABCR operon that plays roles in regulation of virulence, biofilm development and antibiotic resistance. It was hypothesized that the operon also plays a role in persister cell formation. In this study, the persister cell …

A Deeper Look Into The Vastus Medialis: A Stabilizer For The Knee, Connie Nicole Barnes

Undergraduate Honors Capstone Projects

Anterior cruciate ligament tears are one of the most common injuries that occur, especially in female athletes. It requires surgery and months of physical therapy to get these athletes back in playing condition. The angle of women’s hips and lack of strength of inner quadriceps muscles enhances the risk of injuries to the knees. One specific muscle that is known for being a stabilizer of the knee and may help in preventing ACL tears is the vastus medialis. By understanding what exercises activate this muscle the most, conditioning plans and preventative workouts need to be created to help female athletes …

Evaluation Of Long-Term Effects Of Mild Traumatic Brain Injury On Visual Motor Control Of Ncaa Division I Football Athletes, Kathryn Delost

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Context: Current concussion evaluation assessments rely largely on static measures that may not detect subtle changes in behavior. Dynamic evaluation, such as visual-motor tracking tasks, may reveal subtle and meaningful changes in motor behavior post-concussion. Objective: This study compared measurements of performance regularity over a time series (approximate entropy; ApEn), which was derived from a visual-motor tracking task performed before concussion, post concussion, and at one month, three months, and six months post concussion. ApEn values were compared for number of previous concussions and playing position groups. Design: ApEn values were collected from the visual-motor tracking task, and history of …

Comparison Of Land And Aquatic Loaded Countermovement Jump Landings In Female Ncaa Division I Collegiate Athletes, Samantha L. Nielson

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

The purpose of this study was to investigate alterations in lower extremity kinematics during the landing phase of a countermovement jump when performed in different environments and under multiple external loads. Twenty-four NCAA Divison I collegiate female athletes performed 12 countermovement jumps on land and 12 jumps in water, submerged to the xiphoid process, for a total of 24 jumps. Within each environmental condition, four loading conditions of three jumps each were performed using a weighted vest: Unloaded, 10%, 20%, or 30% of body mass. The hip, knee, and ankle angles were measured as the smallest angles between the major …

Pitch Perception In Preschool-Age Children Who Are Deaf Or Hard Of Hearing, Megan Lambert

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

This research thesis will 1) provide an overview of the psychoacoustics of music perception, particularly as related to the properties of pitch perception in young children and 2) describe the methods and outcomes of an exploratory study to evaluate the efficacy of obtaining pitch perception data from preschool age children with hearing loss. Each child completed a series of three tasks, including coaching and practice, single note perception, and pitch contrasts. All of the children readily understood the single-note pitch perception task. Pitch contrast performance across participants ranged from 50% to 96% correct for the first data collection period and …

Speaking Disparagingly About Minorities And Lgbt Patients, Michael G. Maihofer Dds

The Journal of the Michigan Dental Association

Regular column featuring ethical guidance and consideration for practicing dentists.

J Mich Dent Assoc May 2017

The Journal of the Michigan Dental Association

Archival issues of the Journal of the Michigan Dental Association may include reports on the activities of the association and its members, clinical articles, information on legal and ethical practice considerations, and perspectives of interest to MDA members and those in the oral health profession.

Training Parents In Descriptive Assessment And Function Identification, Makenzie Sip

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

It is often difficult for parents to address their child’s problem behavior. Children with special needs can display more frequent and intense problem behavior. Therefore, professionals need to help parents of children with special needs identify how to decrease their child’s problem behavior. Professionals help to decrease problem behavior by performing assessments called descriptive assessments to identify why the problem behavior is happening, and then using these assessments to create an appropriate plan of how to prevent and respond to the problem behavior. We examined if parents could be taught the skills necessary to perform descriptive assessments and then use …