Medicine and Health Sciences Commons^™

Ball Release Velocity And Pre-Release Range Of Motion For Five Types Of Softball Pitches, T. Bicko, B. Meyer

International Journal of Exercise Science: Conference Proceedings

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The Effects Of Self-Selected Music On Exercise Performance, B. Benson, P. Cutrufello, M. Landram

International Journal of Exercise Science: Conference Proceedings

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Performance Measures In Female Collegiate Soccer Players According To Acl Injury Status, N. Bennett, N. Foggia, K. Wisniewski

International Journal of Exercise Science: Conference Proceedings

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Differences In Male And Female Scapular Strength And The Relationship To Sprint Swimming Performance, A. Beethe, E. Nagle, C. Connaboy, J. Abt, S. Lephart, M. Lovalekar, T. Nagai

International Journal of Exercise Science: Conference Proceedings

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The Acute Effect Of Intermittent Fasting On Resting Energy Expenditure In College-Aged Males, C. Beaumont, R. Stauffer, T. Flink

International Journal of Exercise Science: Conference Proceedings

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Influence Of Anthropometric Variables On Three Different Maximal Oxygen Consumption Units: Nhanes 2003-2004, N. Barrios, E. Matthews, P. Hosick

International Journal of Exercise Science: Conference Proceedings

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Blood Pressure Responses To Metaboreflex Activation During Acute And Chronic Volume Loading, M. Babcock, M. Brian, A. Robinson, J. Watso, M. Wenner, W. Farquhar

International Journal of Exercise Science: Conference Proceedings

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Effects Of Dynamic Cycling On Motor Function, Gait, And Balance In Individuals With Parkinson's Disease, D. Ault, A. Ridgel

International Journal of Exercise Science: Conference Proceedings

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Perceived Intensity Level During Treadmill Exercise, B. Arney, K. Wisniewski

International Journal of Exercise Science: Conference Proceedings

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Cardiovascular Endurance Among College Students: How Is It Related To Overall Fitness?, D. Andrades, A. Barton, J. Moxley, A. Vigo

International Journal of Exercise Science: Conference Proceedings

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Accuracy And Practicality Of A Nirs Device On Blood Lactate Levels, J. Abbott, M. Whidden

International Journal of Exercise Science: Conference Proceedings

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Dietary Alkylresorcinols And Cancer Prevention: A Systematic Review, Joanna Kruk, Basil Aboul‑Enein, Joshua Bernstein, Mariola Marchlewicz

Health & Wellness Department Faculty Publications and Research

The potential role of alkylresorcinol compound from whole grains for prevention and inhibition of human cancer cell lines has been reported in observational and in vitro studies. The objective of this study was to present an updated review on the association between alkylresorcinols and cancer risk and aspects of their bioactivity with implications for carcinogenesis. Relevant studies were identifed by searching PubMed, Scopus, ProQuest, EBSCOhost, SpringerLink, ArticleFirst, Taylor & Francis, Wiley Online, and ScienceDirect electronic databases using these search terms and key words: alkylresorcinols, cancer, carcinoma, risk. Furthermore, references from retrieved articles were also reviewed. Four observational and 10 in …

The Effects Of Proprioceptive Neuromuscular Facilitation Scapular Motor Control Intervention On The Rehabilitation Of Shoulder Impingement Syndrome, Madison R. Dorn, Rebekah R. Shindelar, Rick C. Hjelm, Seth A. Paradis

Applied Health Sciences Student Works

OBJECTIVE: Shoulder impingement syndrome (SIS) accounts for 44-65% of total shoulder complaints. Previous research has analyzed the effectiveness of scapular-focused SIS treatment, but little research has been performed evaluating the effectiveness of proprioceptive neuromuscular facilitation (PNF) treatment. The aim of this study is to examine the effects of PNF scapular motor control intervention for SIS. METHODS: Patients from the Roseville Medical Center ages 18-64 were randomized to a PNF-treatment or control group to undergo a 4 to 6 week intervention. Prior to each visit, patients completed the Disabilities of the Arm, Shoulder and Hand (DASH) functional survey and evaluated their …

Injury-Induced Microvesicle Particle Release In Human Skin Explant Tissue, Katherine E. Fahy, Langni Liu, Christine M. Rapp, Eric J. Romer, Christina E. Borchers, Richard Simman, Ji C. Bihl, Jeffrey B. Travers

Pharmacology and Toxicology Faculty Publications

Microvesicle particles (MVP) are 100-1000 nm vesicles that bud from the cell membrane and transmit intercellular signals locally and systemically via their bioactive cargo (e.g. cytokines).

The Clinical Impact Of Copy Number Variants In Inherited Bone Marrow Failure Syndromes, Nicolas Waespe, Santhosh Dhanraj, Manju Wahala, Elena Tsangaris, Tom Enbar, Bozana Zlateska, Hongbing Li, Robert J Klaassen, Conrad V Fernandez, Geoff D E Cuvelier, John K Wu, Yves D Pastore, Mariana Silva, Jeffrey H Lipton, Joseé Brossard, Bruno Michon, Sharon Abish, Macgregor Steele, Roona Sinha, Mark J Belletrutti, Vicky R Breakey, Lawrence Jardine, Lisa Goodyear, Liat Kofler, Michaela Cada, Lillian Sung, Mary Shago, Stephen W Scherer, Yigal Dror

Paediatrics Publications

Inherited bone marrow failure syndromes (IBMFSs) comprise a genetically heterogeneous group of diseases with hematopoietic failure and a wide array of physical malformations. Copy number variants (CNVs) were reported in some IBMFSs. It is unclear what impact CNVs play in patients evaluated for a suspected diagnosis of IBMFS. Clinical and genetic data of 323 patients from the Canadian Inherited Marrow Failure Registry from 2001 to 2014, who had a documented genetic work-up, were analyzed. Cases with pathogenic CNVs (at least 1 kilobasepairs) were compared to cases with other mutations. Genotype-phenotype correlations were performed to assess the impact of CNVs. Pathogenic …

Transcranial Direct Current Stimulation And Sports Performance, Dylan J. Edwards, Mar Cortes, Susan Wortman-Jutt, David Putrino, Marom Bikson, Gary Thickbroom, Alvaro Pascual-Leone

Publications and Research

No abstract provided.

Retrospective Comparative Costs And Benefits Of Registered Nurses (Rns) In A Perioperative 101 Program Residency (P101); An Immersive Perioperative Specialty Residency (Psr); And Registered Nurses Hired Into General Perioperative Services From 2009-2016, Johanna K. Stiesmeyer

Doctor of Nursing Practice Scholarly Projects

This study addresses the cost to benefit ratio of a healthcare organization’s investment in specialty perioperative residency programs for newly licensed registered nurses and experienced registered nurse orienting into perioperative services. The outcomes for transition to practice residency programs is widely reported however a standardized approach to measuring and reporting cost to benefit ratios and return on investment to these programs as well as specialty residencies remains an opportunity. This study contributes to national standardization and approach by defining the costs of a perioperative residency program and determining the cost to benefit ratio using a return on investment calculator. The …

Enhancing Clinical Manager Self-Efficacy Through A Change Management Academy, Chet Hurley Doering Iii

Doctor of Nursing Practice Scholarly Projects

Healthcare systems are facing increased pressure to develop their clinical managers’ abilities and competencies leading change. Clinical managers that are equipped with these capabilities can influence greater quality and safety outcomes for patients. Literature and industry findings both strongly suggest that leaders who possess increased self-efficacy are more effective leading change. This is demonstrated at the unit and system level through improved project management, successfully executing strategic initiatives, retaining staff, and being more fiscally responsible. There are significant clinical and business advantages for healthcare systems that foster change management skills for their clinical managers When organizations do not provide support, …

Microarray Dataset Of Transient And Permanent Dna Methylation Changes In Hela Cells Undergoing Inorganic Arsenic-Mediated Epithelial-To-Mesenchymal Transition, Meredith Eckstein, Matthew Rea, Yvonne N. Fondufe-Mittendorf

Molecular and Cellular Biochemistry Faculty Publications

The novel dataset presented here represents the results of the changing pattern of DNA methylation profiles in HeLa cells exposed to chronic low dose (0.5 µM) sodium arsenite, resulting in epithelial-to-mesenchymal transition, as well as DNA methylation patterns in cells where inorganic arsenic has been removed. Inorganic arsenic is a known carcinogen, though not mutagenic. Several mechanisms have been proposed as to how inorganic arsenic drives carcinogenesis such as regulation of the cell׳s redox potential and/or epigenetics. In fact, there are gene specific studies and limited genome-wide studies that have implicated epigenetic factors such as DNA methylation in inorganic arsenic-mediated …

Discovery Of A Diaminopyrimidine Flt3 Inhibitor Active Against Acute Myeloid Leukemia, Jamie A. Jarusiewicz, Jae Yoon Jeon, Michele C. Connelly, Yizhe Chen, Lei Yang, Sharyn D. Baker, R. Kiplin Guy

Pharmaceutical Sciences Faculty Publications

Profiling of the kinase-binding capabilities of an aminopyrimidine analogue detected in a cellular screen of the St. Jude small-molecule collection led to the identification of a novel series of FMS-like tyrosine kinase 3 (FLT3) inhibitors. Structure–activity relationship studies led to the development of compounds exhibiting good potency against MV4-11 and MOLM13 acute myelogenous leukemia cells driven by FLT3, regardless of their FLT3 mutation status. In vitro pharmacological profiling demonstrated that compound 5e shows characteristics suitable for further preclinical development.

The Academic Research Library And Science Education: A Roadmap For The Journey, Sue Ann Gardner

University of Nebraska-Lincoln Libraries: Presentations

Science libraries are integral to the process of science inquiry.

Science education is facilitated within science libraries.

The future of science libraries is predicated on librarians maintaining a meaningful relationship with those engaging in scholarship.

Science libraries need to combine traditional and emerging service models, provide access to a wide array of materials, incorporate appropriate technology, and offer ergonomic work spaces to promote effective learning.

The science commons includes varied work spaces which encourage innovation and creativity, facilitate situated and active learning, and promote communities of practice.

The National Science Education Standards definition of science inquiry includes the diverse ways …

Adenocarcinoma In A Koff Urinary Ileal Diversion., Bradley Sherman, Frederick Taylor

Oncology Articles

The use of an ileal conduit as a means of treatment for bladder cancer or dysfunction is widely used and understood. However, long term surveillance of that conduit has not been strongly established and set forth as a means of screening. We present a 76yo female with a history of neurogenic bladder secondary to paraplegia who underwent the formation of a "Koff" pouch as a conduit. Nineteen years later she presents with hematuria and was found to have adenocarcinoma originating in her conduit.

Injury-Induced Microvesicle Particle Release In Human Skin Explant Tissue, Katherine E. Fahy, Langni Liu, Christina E. Borchers, Richard Simman, Ji C. Bihl, Jeffrey B. Travers

Pharmacology and Toxicology Faculty Publications

Microvesicle particles (MVP) are 100-1000 nm vesicles that bud from the cell membrane and transmit intercellular signals locally and systemically via their bioactive cargo (e.g. cytokines). We have previously shown that thermal burn injury or UVB radiation result in the formation Platelet Activating Factor (PAF), and UVB or a PAF agonist (CPAF) can promote MVP formation in keratinocytes. Thermal burn and UVB radiation can result in systemic effects, even though their injury is localized to the skin. We therefore propose that PAF-producing injuries, UVB irradiation or thermal burn injury, result in the formation of MVPs that can potentially transport cytokines …

Combating Workplace Violence: An Evidence Based Initiative, Diana L. Giordano

Evidence-Based Practice Project Reports

Patient/visitor violence against healthcare (HC) employees is a type of workplace violence (WPV) and considered a dangerous hazard within HC occupations (Bureau of Labor Statistics, 2015). Lack of recognition of the true incidence and underreporting of WPV may contribute to a false sense of security within a HC facility (HCF). Therefore, fully addressing the problem may be met with administrative resistance, resulting in poor employee perceptions of support and commitment for a zero-violence environment. A retrospective analysis was conducted on the HCF’s online incident reports, security request calls, and data from a previously deployed WPV employee survey. The emergency department …

The Skin Cancer Health Crisis And Recommended Intervention Methods, Blaire Brooks

Senior Theses

Despite the increasing research connecting UVR exposures to skin cancer, rates of skin cancer are rising. Skin cancer is now the most common form of cancer and there are significant health care costs associated with treating the cases (Balk et al., 2013). As a result, the United States needs greater initiatives to increase educational programs, physician counseling, and political action regarding ultraviolet exposure and incidence of skin cancer. Evaluation of the types of skin cancer, perceptions of tanning, and current regulations and recommendations are required in order to form the initiatives to combat the growth of skin cancer.

A Serosurvey Of Selected Cystogenic Coccidia In Spanish Equids: First Detection Of Anti-Besnoitia Spp. Specific Antibodies In Europe, Daniel Gutiérrez-Expósito, Ignacio García-Bocanegra, Daniel K. Howe, Antonio Arenas-Montes, Michelle R. Yeargan, Sallyanne L. Ness, Luis M Ortega-Mora, G. Álvarez-García

Veterinary Science Faculty Publications

Background: Equine besnoitiosis, caused by Besnoitia bennetti, and equine protozoal myeloencephalitis (EPM), caused by Sarcocystis neurona and Neospora hughesi are relevant equine diseases in the Americas that have been scarcely studied in Europe. Thus, a serosurvey of these cystogenic coccidia was carried out in Southern Spain. A cross-sectional study was performed and serum samples from horses (n = 553), donkeys (n = 85) and mules (n = 83) were included. An in-house enzyme-linked immunosorbent assay (ELISA) was employed to identify a Besnoitia spp. infection and positive results were confirmed by an a posteriori western blot. For Neospora …

The Foxo Transcription Factor Controls Insect Growth And Development By Regulating Juvenile Hormone Degradation In The Silkworm, Bombyx Mori, Baosheng Zeng, Yuping Huang, Jun Xu, Takahiro Shiotsuki, Hua Bai, Subba Reddy Palli, Yongping Huang, Anjiang Tan

Entomology Faculty Publications

Forkhead box O (FOXO) functions as the terminal transcription factor of the insulin signaling pathway and regulates multiple physiological processes in many organisms, including lifespan in insects. However, how FOXO interacts with hormone signaling to modulate insect growth and development is largely unknown. Here, using the transgene-based CRISPR/Cas9 system, we generated and characterized mutants of the silkworm Bombyx mori FOXO (BmFOXO) to elucidate its physiological functions during development of this lepidopteran insect. The BmFOXO mutant (FOXO-M) exhibited growth delays from the first larval stage and showed precocious metamorphosis, pupating at the end of the fourth instar (trimolter) rather …

Comparison Of Training Models For Hearing Screening Personnel, Ryland Gallagher, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Early identification of permanent hearing loss begins with the competency of the individuals completing a hearing screening in being able to identify children who are at-risk for hearing loss. The appropriate management of hearing healthcare for children, during the developmental period from birth to school age, requires these individuals to possess knowledge related to screenings, protocols, and follow-up, for children in need of additional diagnostic services. The Early Childhood Hearing Outreach (ECHO) Initiative was formulated by the National Center for Hearing Assessment and Management (NCHAM) as an extension to newborn hearing screening programs. The program focuses on assisting hearing screeners …

Patient Activation Among Diverse Populations: A Systematic Review, Megan Kenney

Student Scholar Symposium Abstracts and Posters

The purpose of this article was to review the current research regarding patient activation among diverse populations. Patient activation is defined as an individual’s knowledge, skill, and confidence in managing his or her own health and health care. A total of 62 articles were used in this review (54 primary research articles, six retrospective analyses, and two systematic reviews). Articles were obtained using the EBSCO search engine through the Leatherby Libraries at Chapman University. Preliminary and secondary searches were conducted using the keywords “patient activation.” Only articles published within the last ten years (2007 to 2017) were included to ensure …

Working It Out: An Examination Of Modern Exercise Culture As Displayed On A College Campus, Mary Bolgan

Senior Theses

When asked to describe, as simplistically as possible, what one believes to be the most basic needs for human survival, it is likely that a few concepts will come up repeatedly: food, shelter, and procreation. In modern times, barriers to these needs tend to be financial resource. However, this has not always been the case. In primitive times, a third necessity would be needed to survive, that being a certain degree of physical fitness. To obtain food and build shelter, our ancestors had to have a great deal of physical competency to be able to hunt, gather, build, and keep …