Medicine and Health Sciences Commons^™

An Item-Response Theory Approach To Safety Climate Measurement: The Liberty Mutual Safety Climate Short Scales, Yueng-Hsiang Huanga, Jin Lee, Zhuo Chen, Mackenna Laine Perry, Janelle H. Chung, Mo Wang

Psychology Faculty Publications and Presentations

Zohar and Luria’s (2005) safety climate (SC) scale, measuring organization- and group- level SC each with 16 items, is widely used in research and practice. To improve the utility of the SC scale, we shortened the original full-length SC scales. Item response theory (IRT) analysis was conducted using a sample of 29,179 frontline workers from various industries. Based on graded response models, we shortened the original scales in two ways: (1) selecting items with above-average discriminating ability (i.e. offering more than 6.25% of the original total scale information), resulting in 8-item organization-level and 11-item group-level SC scales; and (2) selecting …

The Effect Of Characteristics Of Proteins Fed During Gestation And Lactation On Development Of Metabolic Syndrome In Dams And Male Offspring Of Wistar Rats, Alireza Jahan-Mihan, Corinne A. Labyak, Andrea Y. Arikawa

Nutrition and Dietetics Faculty Research and Scholarship

Objective

The objective of the study is to examine the role of characteristics of proteins in maternal and weaning diets on risk of metabolic syndrome in male offspring.

Methods

Pregnant Wistar rats were allocated to two groups (n = 12) and were fed the AIN‐93G diets based on either intact protein‐based diet (IPD) or mixed amino acid‐based diet (AAD) from day 3 of gestation throughout gestation and lactation. Male offspring were weaned to either an IPD or AAD diet for 18 weeks.

Results

In dams, AAD group had lower body weight in post‐partum period and higher pulse rate compared …

Comparative Effectiveness Research Of Disease-Modifying Therapies For The Management Of Multiple Sclerosis: Analysis Of A Large Health Insurance Claims Database., Aaron Boster, Jacqueline Nicholas, Ning Wu, Wei-Shi Yeh, Monica Fay, Michael Edwards, Ming-Yi Huang, Andrew Lee

Neuroscience Articles

INTRODUCTION: Limited data are available on the real-world effectiveness of newer oral disease-modifying therapies (DMTs) in multiple sclerosis. The purpose of this study was to retrospectively compare the real-world effectiveness of dimethyl fumarate (DMF), fingolimod, teriflunomide, and injectable DMTs in routine clinical practice based on US claims data.

METHODS: Patients newly-initiating DMF, interferon beta (IFNβ), glatiramer acetate (GA), teriflunomide, or fingolimod in 2013 were identified in the Truven MarketScan Commercial Claims Databases (N = 6372). Relapse episodes were identified based on a published claim-based algorithm and used to determine the annualized relapse rate (ARR) for the year before and after …

Risk Factors For Pressure Injuries Among Critical Care Patients: A Systematic Review, Jenny Alderden, June Rondinelli, Ginette Pepper, Mollie Cummins, Joanne Whitney

Nursing Faculty Publications and Presentations

Objective: To identify risk factors independently predictive of pressure injury (also known as pressure ulcer) development among critical-care patients.

Design: We undertook a systematic review of primary research based on standardized criteria set forth by the Institute of Medicine.

Data sources: We searched the following databases: CINAHL (EBSCOhost), the Cochrane Library (Wilson), Dissertations & Theses Global (ProQuest), PubMed (National Library of Medicine), and Scopus. There was no language restriction.

Method: A research librarian coordinated the search strategy. Articles that potentially met inclusion criteria were screened by two investigators. Among the articles that met selection criteria, one …

Transcriptional And Posttranscriptional Regulation Of Shigella Shut In Response To Host-Associated Iron Availability And Temperature, Yahan Wei, Andrew B. Kouse, Erin R. Murphy

School of Podiatric Medicine Publications

Like most bacteria, Shigella must maintain a precise balance between the necessity and toxicity of iron; a balance that is achieved, at least in part, by regulating the production of bacterial iron acquisition systems in response to specific environmental signals. Using the Shigella heme utilization (Shu) system, S. dysenteriae is able to acquire iron from heme, a potentially rich source of nutritional iron within the otherwise iron-limited environment of the human host. Investigations presented within reveal two distinct molecular mechanisms underlying previously uncharacterized transcriptional and translational regulation of shuT, a gene encoding the periplasmic-binding component of the Shu system. …

Effects Of Low Dose Mixtures Of 3,4-Methylenedioxypyrovalerone And Cocaine On Locomotor Activity And Brain Monoamine Content In Sprague-Dawley Rats, Robert J. Kohler

Masters Theses

Synthetic cathinones, known as “bath salts” on the illicit drug market, pose a significant and growing public health concern. 3,4-Methylenedioxypyrovalerone (MDPV), one of several popular constituents of the illicit bath salts, produces similar pharmacological actions to cocaine, albeit with greater potency. The present study sought to characterize behavioral and neurochemical effects of repeated exposure to MDPV alone and in combination with cocaine. Male Sprague-Dawley rats were randomly assigned to one of four treatments: 1 mg/kg MDPV, 5 mg/kg cocaine, 1 mg/kg MDPV + 5 mg/kg cocaine, or saline. Locomotor activity was assessed for one hour immediately before and one hour …

Does The Spine Surgeon’S Experience Affect Fracture Classification, Assessment Of Stability, And Treatment Plan In Thoracolumbar Injuries?, Shanmuganathan Rajasekaran, Rishimugesh Kanna, Gregory D. Schroeder, Frank C. Oner, Luiz Vialle, Jens R. Chapman, Marcel Dvorak, Michael Fehlings, Ajoy P. Shetty, Klaus J. Schnake, Frank M. Kandziora, Alex R. Vaccaro

Rothman Institute Papers

Study Design: Prospective survey-based study. Objectives: The AO Spine thoracolumbar injury classification has been shown to have good reproducibility among clinicians. However, the influence of spine surgeons’ clinical experience on fracture classification, stability assessment, and decision on management based on this classification has not been studied. Furthermore, the usefulness of varying imaging modalities including radiographs, computed tomography (CT) and magnetic resonance imaging (MRI) in the decision process was also studied. Methods: Forty-one spine surgeons from different regions, acquainted with the AOSpine classification system, were provided with 30 thoracolumbar fractures in a 3-step assessment: first radiographs, followed by CT and MRI. …

Determinants And Impact Of Giardia Infection In The First 2 Years Of Life In The Mal-Ed Birth Cohort, Elizabeth T. Rogawski, Luther A. Bartelt, James A. Platts-Mills, Jessica C. Seidman, Amidou Samie, Alexandre Havt, Sudhir Babji, Shahida Qureshi, Sadia Shakoor, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Giardia are among the most common enteropathogens detected in children in low-resource settings. We describe here the epidemiology of infection with Giardia in the first 2 years of life in the Etiology, Risk Factors, and Interactions of Enteric Infections and Malnutrition and the Consequences for Child Health and Development Project (MAL-ED), a multisite birth-cohort study.
Methods: From 2089 children, 34916 stool samples collected during monthly surveillance and episodes of diarrhea were tested for Giardia using an enzyme immunoassay. We quantified the risk of Giardia detection, identified risk factors, and assessed the associations with micronutrients, markers of gut inflammation and …

Complex Coordinated Terrorist Attack: Considerations For Practical Emergency Preparedness And Resiliency Exercises, Trent Elliott

Master of Public Health Program Student Publications

In today’s geopolitical environment, the emergence of religious extremism is becoming more prevalent. Justified as a holy war, jihadists are becoming more brash and calculated in attacking targets to inflict maximum damage and instill the greatest amount of fear. Coordinated, lethal, terrorist attacks against innocent targets; killing indiscriminately is a preferred tactic of extremists. Multiple attacks, coordinated either in proximity or timing, using firearms, explosive devices, or fire to inflict damage and disrupt life is the basis of a Complex Coordinated Terrorist Attack (CCTA).

City and regional emergency response plans should address mitigating efforts to a CCTA. Community strength and …

Laboratory Analysis Of Risky Driving At 0.05% And 0.08% Blood Alcohol Concentration, Nicholas A. Van Dyke, Mark T. Fillmore

Psychology Faculty Publications

Background—The public health costs associated with alcohol-related traffic crashes are a continuing problem for society. One harm reduction strategy has been to employ per se limits for blood alcohol concentrations (BACs) at which drivers can legally operate motor vehicles. This limit is currently 0.08% in all 50 US states. Recently, the National Transportation Safety Board proposed lowering the legal limit to 0.05 % (NTSB, 2013). While research has well-validated the ability of alcohol to impair driving performance and heighten crash-risk at these BACs, relatively little is known about the degree to which alcohol might increase drivers’ risk-taking.

Methods—Risk-taking …

Compulsive Buying And Quality Of Life: An Estimate Of The Monetary Cost Of Compulsive Buying Among Adults In Early Midlife, Chenshu Zhang, Judith S. Brook, Carl G. Leukefeld, Mario De La Rosa, David W. Brook

Behavioral Science Faculty Publications

The aims of this study were to examine the associations between compulsive buying and quality of life and to estimate the monetary cost of compulsive buying for a cohort of men and women at mean age 43. Participants came from a community-based random sample of residents in two New York counties (N=548). The participants were followed from adolescence to early midlife. The mean age of participants at the most recent interview was 43.0 (SD=2.8). Fifty five percent of the participants were females. Over 90% of the participants were white. Linear regression analyses showed that compulsive buying was significantly associated with …

Care Of The Terminally Ill Patient In India: Comments On The Proposed Legislation, Aju Mathew, M. R. Rajagopal

Internal Medicine Faculty Publications

No abstract provided.

06-06-2017 Hsc Committee Agenda, Patrice Martin, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Red Grain Sorghum Whole Kernel Crude Lipid Protects Energy Metabolism And Short Chain Fatty Acid Profile In A Hamster Model To Minimize Intestinal Stress Caused By A High Fat Diet, Haowen Qiu

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Multiple studies have shown throughout the past 10+ years that grain sorghum (GS) lipid extract protects against high plasma and hepatic cholesterol and, to a lesser degree, positively modulate the gut microbiota in response to a high fat (HF) diet. However, the impact of GS lipids on intestinal stress induced by such a diet remains largely unknown. The objective of this project was to determine the ability of GS crude lipid (GS-CL) obtained from the surface of GS whole kernel to protect energy metabolism and short chain fatty acid (SCFA) profile produced by the gut microbiome that may be negatively …

Body Mass Index Associations Between Mother And Offspring From Birth To Age 18: The Fels Longitudinal Study, Stacie S. Swanton, Audrey C. Choh, Miryoung Lee, Lloyd L. Laubach, Jon K. Linderman, Stefan A. Czerwinski, Matthew J. Peterson

Health and Sport Science Faculty Publications

Background: Parental obesity is a known determinant of childhood obesity. Previous research has shown a strong maternal influence on body mass index (BMI) during infancy and early childhood.

Objectives: The purpose of this research was to investigate the BMI associations between mother and offspring from birth to age 18 years.

Methods: Participants were selected from the Fels Longitudinal Study. The current study sample includes 427 (215 mother/son and 212 mother/daughter) mother/child pairs. These pairs are repeatedly measured at multiple age groups in children, resulting in a total of 6,263 (3,215 mother/son, 3,048 mother/daughter) observations for data analysis. Inclusion criteria were …

Risk Of Incident Clinical Diagnosis Of Alzheimer's Disease-Type Dementia Attributable To Pathology-Confirmed Vascular Disease, Hiroko H. Dodge, Jian Zhu, Randy Woltjer, Peter T. Nelson, David A. Bennett, Nigel J. Cairns, David W. Fardo, Jeffrey A. Kaye, Deniz-Erten Lyons, Nora Mattek, Julie A. Schneider, Lisa C. Silbert, Chengjie Xiong, Lei Yu, Frederick A. Schmitt, Richard J. Kryscio, Erin L. Abner, Smart Data Consortium

Sanders-Brown Center on Aging Faculty Publications

INTRODUCTION: The presence of cerebrovascular pathology may increase the risk of clinical diagnosis of Alzheimer's disease (AD).

METHODS: We examined excess risk of incident clinical diagnosis of AD (probable and possible AD) posed by the presence of lacunes and large infarcts beyond AD pathology using data from the Statistical Modeling of Aging and Risk of Transition study, a consortium of longitudinal cohort studies with more than 2000 autopsies. We created six mutually exclusive pathology patterns combining three levels of AD pathology (low, moderate, or high AD pathology) and two levels of vascular pathology (without lacunes and large infarcts or with …

Clinical Application Of Ceramics In Anterior Cervical Discectomy And Fusion: A Review And Update, Shayan A. Zadegan, Aidin Abedi, Seyed B. Jazayeri, Hirbod Bonaki, Alex R. Vaccaro, Vafa Rahimi-Movaghar

Rothman Institute Papers

Study Design: Narrative review. Objectives: Anterior cervical discectomy and fusion (ACDF) is a reliable procedure, commonly used for cervical degenerative disc disease. For interbody fusions, autograft was the gold standard for decades; however, limited availability and donor site morbidities have led to a constant search for new materials. Clinically, it has been shown that calcium phosphate ceramics, including hydroxyapatite (HA) and tricalcium phosphate (TCP), are effective as osteoconductive materials and bone grafts. In this review, we present the current findings regarding the use of ceramics in ACDF. Methods: A review of the relevant literature examining the clinical use of ceramics …

Transitional Healthcare Coordination In New York City Jails Among People With Chronic Health Conditions: Contributions To Reduced Reincarceration And Improved Health, Janet J. Wiersema

Dissertations and Theses

People in correctional settings often have poorer health than the general US population. For example, it is estimated that 27.9% of persons in jail have hypertension, 8.1% have diabetes, and 1.6% have HIV, compared to 25.6%, 6.5%, and 0.5%, respectively, in the general population. Jail and other correctional settings are also increasingly recognized as viable places to engage poor and underserved communities into the healthcare system by offering transitional care coordination services to connect people to healthcare and other services to meet priorities after incarceration. At the same time, recidivism is an issue—over 50% of persons in New York City …

A Multilevel Analysis To Understand The Role Of The Federal Vaccine Financing Program In Socioeconomic Disparities In Vaccination Coverage Among Children And Adolescents In New York City, Alexandra Ternier

Dissertations and Theses

A Multilevel Analysis to Understand the Role of the Federal Vaccine Financing Program in Socioeconomic Disparities in Vaccination Coverage among Children and Adolescents in New York City

Objectives: The purpose of this study was to examine the role of the federal vaccine financing program, the Vaccines For Children (VFC) program, in vaccine series completeness among children and adolescents in New York City. In addition, we aimed to investigate possible effect measure modification by selected neighborhood variables to explain socioeconomic disparities in vaccination coverage.

Methods: We used data from the New York City (NYC) Citywide Immunization Registry (CIR) and the American …

Faculty Perceptions Of Readiness To Implement Interprofessional Education In Athletic Training, Meredith M. Parry

Student Dissertations

As the athletic training profession takes steps towards the next level as an allied health care profession, advocates for the profession are positioning athletic trainers as key players in the interprofessional health care team. Recently, the CAATE has pronounced a move for athletic training education to transition all entry-level education to professional master’s degree programs. CAATE is also requesting that athletic training education programs find means to align with other healthcare profession education programs within their institution and actively engage in planned and continuous interprofessional learning activities. This study explored the gap in knowledge regarding athletic training faculty perceptions on …

Exciting Times In South-Asian Midwifery, Rafat Jan, Edwin Van Teijlingen

Journal of Asian Midwives (JAM)

No abstract provided.

Evaluating A Community Maternal Health Programme: Lessons Learnt, Sheetal Sharma, Padam Simkhada, Vanora Hundley, Edwin Van Teijlingen, Jane Stephens, Ram Chandra Silwal, Catherine Angell

Journal of Asian Midwives (JAM)

Using the example of a community-based health promotion intervention, this paper explores the important triangle between health promotion theory, intervention design, and evaluation research. This paper first outlines the intervention and then the mixed-method evaluation.

In 2007, a non-governmental organisation (NGO) designed and implemented an intervention to improve the uptake of maternal health provision in rural Nepal. A community-based needs assessment preceded this novel health-promotion intervention that empowered women with information on the benefits of seeking care. The intervention had a flexible design and, at several points, the intervention’s progress was assessed and, where necessary, changes were made. The intervention …

Knowledge, Attitude, And Practices Of Mid-Level Providers Regarding Post Abortion Care In Sindh, Pakistan, Marina Baig, Rafat Jan, Arusa Lakhani, Sadia Abbas Ali, Kiran Mubeen, Shahnaz Shahid Ali, Farzana Adnan

Journal of Asian Midwives (JAM)

Background: In Pakistan, half of all pregnancies are unintended (4.2 million per year); out of which 2.2 million end in induced abortions. Almost 700,000 women seek medical treatment for post abortion complications every year. This necessitates access to quality Post-Abortion Care (PAC) services from skilled providers in Pakistan.
Purpose: This study aimed to assess the knowledge, attitude and practices of Mid-Level Providers (MLPs) regarding PAC services in Sindh, Pakistan.
Method: The study utilized a cross-sectional design. Convenience sampling was used to recruit 116 MLPs, including Nurse Midwives (NM), Lady Health Visitors (LHVs), and Community Midwives (CMWs) from different parts …

Birth Experiences Of Primiparous Turkish Women: Public And Private Hospitals, Filiz Okumus

Journal of Asian Midwives (JAM)

Introduction: We wished to better understand primiparous women’s childbirth experiences in private and public hospitals. Within the context of high caesarean section rates, in both private and public hospitals in Turkey, the experiences of women who delivered vaginally needs to be considered if we aim to decrease the number of caesarean births. We, therefore, conducted a descriptive study of women’s vaginal birth experiences in two hospitals in Istanbul.
Methods: Two hundred and forty primiparous women, from two hospitals (one public, one private), who had vaginal births, were included in this descriptive study. Information was obtained from medical records and through …

The Historical Development Of The Midwifery Profession In Bangladesh, Malin Bogren, Farida Begum, Kerstin Erlandsson

Journal of Asian Midwives (JAM)

Sexual and reproductive health and rights have been identified as the core areas of practice, theory and research for the midwifery profession. The midwifery profession, as defined by the International Confederation of Midwives Global Standards, is new in Bangladesh. This paper aims to give an overview of the historical process that has taken place in the past decades to develop the midwifery profession in Bangladesh. The professional development of midwives is the result of many years of collaboration and relationship building among stakeholders such as the government, non-government organizations, academia, professional associations, United Nations agencies, and donors. All are working …

Blastocystis Sp. En Humanos: Actualización Y Experiencia Clínico-Terapéutica [Blastocystis Sp. In Humans: Update And Clinical-Therapeutic Experience], Nathalie Chacon, Carmen Durán, María Antonia De La Parte

Physician Assistant Studies Faculty Publications

Blastocystis sp. es uno de los parásitos del humano más frecuentemente identificados en el laboratorio clínico durante el estudio parasitológico de las muestras de heces. En esta revisión se actualizan los aspectos relativos a la diversidad genética y especificidad del huésped, la taxonomía, caracterización molecular, formas clínicas y experiencia terapéutica en pacientes inmuno-competentes y comprometidos, sintomáticos y asintomáticos, de la consulta de la Sección de Geohelmintiasis del Instituto de Medicina Tropical de la Facultad de Medicina de la Universidad Central de Venezuela, proponiendo el secnidazol como droga de primera elección. Se analiza la presencia de Blastocystis como patógeno humano o …

A Rare Bilateral Second Arch Branchial Anomaly, Pillai Suresh, Agarwal Ashish C, Mahesh S G, Mallick Shaharyar A

Manipal Journal of Medical Sciences

Branchial cysts, sinuses, and fistulas are rare anomalies, and bilateral presentation is even more uncommon, consisting of only two to three percent of all cases. There have been several reports of bilateral branchial cysts or sinuses, but only a few cases of bilateral branchial fistulas have been reported. But in our review of literature, we were not able to come across a similar case of a branchial fistula on one side and a branchial sinus on the other. The most comparable occurrence we could find was of a simultaneous second branchial cleft fistula on the left and right-sided sinus with …

Differential Effects Of Infusion Of Orexin A And Orexin B Into Basolateral Amygdala On Feeding Behaviour In Albino Rats, Ganaraja B, Rashmi K S, Santosh Mayannavar

Manipal Journal of Medical Sciences

No abstract provided.

Reliability And Validity Of A Biomechanically Based Analysis Method For The Tennis Serve, Natalie L. Myers, W. Ben Kibler, Leah Lamborn, Belinda J. Smith, Tony English, Cale A. Jacobs, Timothy L. Uhl

Physical Therapy Faculty Publications

Background: An observational tennis serve analysis (OTSA) tool was developed using previously established body positions from three-dimensional kinematic motion analysis studies. These positions, defined as nodes, have been associated with efficient force production and minimal joint loading. However, the tool has yet to be examined scientifically.

Purpose: The primary purpose of this investigation was to determine the inter-observer reliability for each node between two health care professionals (HCPs) that developed the OTSA, and secondarily to investigate the validity of the OTSA.

Methods: Two separate studies were performed to meet these objectives. An inter-observer reliability study preceded the …

Care Coordination For Community Transitions For Individuals Post-Stroke Returning To Low-Resource Rural Communities, Patrick H. Kitzman, Keisha Hudson, Violet Sylvia, Frances Feltner, Johnnie Lovins

Physical Therapy Faculty Publications

High rates of hospital readmissions have been shown within 12 months post-discharge from inpatient rehabilitation following stroke. Multiple studies coupled with our previous work indicate a need for care support for stroke survivors’ transitions to the community. The Kentucky Care Coordination for Community Transitions (KC³T) program was developed to provide access to medical, social, and environmental services to support community transitions for individuals with neurological conditions and their caregivers living in Kentucky. This program assessment was conducted to determine the effectiveness of using a specially trained community health worker to support community transitions. Thirty acute stroke survivors were …