Medicine and Health Sciences Commons^™

Bleeding Ulcers: Effect Of Low Dose Aspirin - Our Experience, Zaim Gashi, Elton Bahtiri, Fadil Sherifi

UBT International Conference

Aspirin is among the most commonly used pharmaceutical products used for the management of fever, to relieve mild to moderate pain, to reduce swelling in inflammatory conditions such as arthritis, while a low dose aspirin is used to prevent blood clots. The latter effect reduces the risk of stroke and heart attack. However, its use is associated with gastrointestinal and other complications. The aim of this study was to evaluate the influence of aspirin in bleeding ulcers. 122 patients were included in this prospective comparative study that were divided in two groups: the first group consisting of 60 patients that …

Prevalence Of Terminal Renal Disease In Lupus Nephritis Patients, Marsida Duli, Qamil Dika, Xhenila Duli, Joana Hankollari

UBT International Conference

Systemic erythematosus lupus is a chronic inflammatory disease of autoimmune nature. This illness can affect all organs, but one of the most common illnesses is lupus nephritis. Patients with renal impairment, despite aggressive immunosuppressive medication carry the risk of developing terminal renal disease and doing dialysis or renal transplant.The purpose of this study is to reflect global statistics on the frequency of the development of terminal renal disease in lupus nephritis patients as an awareness-raising way to stimulate studies that present a successful treatment or screening protocol in preventing this complication.This study is a review based on the research of …

Trends Of The Contraceptive Medicine Consumption In Kosovo, Arianit Jakupi, Shpend Dragusha, Valon Ejupi, Eda Mehmeti, Agon Hoti

UBT International Conference

One of the main objectives of this research is to obtain data about the consumption of contraceptive medicines in Kosovo, compare to other European countries with drug utilization studies and try to understand the rationale about the obtained results while also measuring progress towards the WHO Millennium Development Goals and Kosovo Health Sectorial Strategy 2017-2021.Regarding the contraceptive medicine consumption it is used the ATC classification of and the Defined Daily Doses per inhabitant per day (DID) as a numeric tool of the analysis. As for the perception of contraceptive dispensing in retail pharmacies are conducted interviews with pharmacists and for …

The Influence Of Division Of Amlodipine Tablets On Their Efficacy And Stability, Brunilda Myftari, Enxhi Andrea, Elton Myftari, Ledjan Malaj

UBT International Conference

Tablet division is a widespread phenomenon nowadays in Albania, because of different factors such as the absence of small dosages in the pharmaceutical market, financial reasons etc. The purpose of this study is to identify the positive and negative aspects of tablets division by patients. It aims to show experimentally if the division affects or not, in a significant way the percentage of the active substance. It was selected Amlodipine as a drug for analysis, because of two reasons. First it is used in chronic therapy and second it is part of the List of Reimbursement of Medicines in the …

Let's Talk! Engaging The Community In Advance Care Planning Through Games., Seth Vanzant, Aleksandra Bacewicz, Alexandria Holmes, Priscilla Shen, Lora Bojilova, Robert Levy, Nicole Defenbaugh Phd, Robert Motley Md

Department of Family Medicine

No abstract provided.

Primary Cilium-Dependent Signaling Mechanisms, Rajasekharreddy Pala, Nedaa Alomari, Surya M. Nauli

Pharmacy Faculty Articles and Research

Primary cilia are hair-like organelles and play crucial roles in vertebrate development, organogenesis, health, and many genetic disorders. A primary cilium is a mechano-sensory organelle that responds to mechanical stimuli in the micro-environment. A cilium is also a chemosensor that senses chemical signals surrounding a cell. The overall function of a cilium is therefore to act as a communication hub to transfer extracellular signals into intracellular responses. Although intracellular calcium has been one of the most studied signaling messengers that transmit extracellular signals into the cells, calcium signaling by various ion channels remains a topic of interest in the field. …

Let's Talk! Engaging The Community In Advance Care Planning Through Games., Seth Vanzant, Aleksandra Bacewicz, Alexandria Holmes, Priscilla Shen, Lora Bojilova Ms2, Robert Levy, Nicole Defenbaugh Phd, Robert Motley Md

USF-LVHN SELECT

No abstract provided.

Spirituality Among Adults Living With Sickle Cell Disease After An Adult Stem Cell Transplantation, Dora L. Clayton-Jones

College of Nursing Faculty Research and Publications

No abstract provided.

A Case Of Refractory Primary Angiitis Of The Central Nervous System., Anam Malik Md, Samer Bolis Do, Susan Kim Md

Department of Medicine

No abstract provided.

Encephalopathy Secondary To Aggressive Cd5+ Dlbcl Versus Herpes Zoster Encephalitis., Kathryn Kass Md

Department of Medicine

No abstract provided.

Sick Sinus Syndrome And Chronic Chagas Cardiomyopathy., Sagar Vadhar Do, Benjamin Sanchez Md

Department of Medicine

No abstract provided.

Bilateral Abducens Palsy Secondary To Metastatic Breast Cancer., Paul Secheresiu Do, Yehia Y. Mishriki Md

Department of Medicine

No abstract provided.

It's Just Diastolic Heart Failure, Right? A Lesson In Humility From A Patient With Ttr-Amyloid Cardiomyopathy., Nathan Brewster Do, Michael Sumner Do, Ross Biggs Do, Ronald S. Freudenberger Md

Department of Medicine

No abstract provided.

Novel Immunotherapy Treatments: The Adverse Effects Of Nivolumab., Angela Magdaleno Do, Wael Hanna Md

Department of Medicine

No abstract provided.

Anti-Yo Positive Paraneoplastic Cerebellar Syndrome In Recurrent Ovarian Carcinoma: A Unique Case To A Rare Phenomenon., Andrew Canakis, Thomas Quinn Do, Ryan Mayo Md

Department of Medicine

No abstract provided.

A Seemingly Innocuous Headache Heralding Onset Of Rare Autoimmune Disorder., Thomas Quinn Do, Noor Salam Md

Department of Medicine

No abstract provided.

Ppi Induced Hypomagnesemic Hypoparathyroidism Leading To Posterio Reversible Encephalopathy Syndrome., Anam Malik Md, Shannon Davis Do, Yehia Y. Mishriki Md

Department of Medicine

No abstract provided.

Ampa-R Antibody Positive Autoimmune Encephalitis: An Under Recognized Cause Of Acute Mental Status Changes., Joseph Moran Do, George Prousi Md, Stacey Smith Md, Facp

Department of Medicine

No abstract provided.

Undergraduate Student Research Practices At Fgcu, Examples From Various Disciplines, Hulya Julie Yazici, Peter Reuter

Florida Statewide Symposium: Best Practices in Undergraduate Research

The purpose of this presentation is to show examples of undergraduate student involvement with research/scholarship, either via course-embedded research practices, or research activities outside the classroom. Examples from health profession, business, STEM disciplines, and humanities will demonstrate how research is implemented and which outcomes for students have been achieved. The presenters will share the challenges and opportunities faced, and probe the audience for their experiences and future directions.

Rolling With A Purpose, Ramune K. Kubilius, Deborah Blecic, Greg Randall Watts, Susan B. Clark, Elizabeth Hinton, David Parker, Taney Shondel

Charleston Library Conference

Moderator Deborah Blecic convened this year’s hosted but no holds barred Lively Lunch session, providing a few general remarks and highlighting why this year’s three presentations were all relevant to this year’s conference theme. Time was left for lively discussion between speakers and session attendees.

Preliminary Evaluation Of An Lyta Pcr Assay For Detection Of Streptococcus Pneumoniae In Urine Specimens From Hospitalized Patients With Community-Acquired Pneumonia, Subathra Marimuthu, James T. Summersgill, Kuldeep Ghosh, Leslie A Wolf

The University of Louisville Journal of Respiratory Infections

Community acquired pneumonia (CAP) due to Streptococcus pneumoniae still occurs in at risk populations, despite the availability of effective vaccines. Laboratory confirmation of S. pneumoniae remains challenging in cases of CAP despite advances in blood culture techniques and the availability of nucleic acid amplification tests such as PCR-based methods. Urine specimens are an attractive sample type because they are non-invasive compared to bronchial washes or whole blood specimens for patients with CAP. While urine specimens have been used successfully in antigen detection assays, they have not been extensively evaluated for PCR-based assays. In this preliminary study, we evaluated the potential …

Distributing Data And Analysis Software Containers For Better Data Sharing In Clinical Research, William A. Mattingly Phd, Stephen Furmanek, Christopher M. Sinclair, Timothy L. Wiemken Phd

The University of Louisville Journal of Respiratory Infections

Introduction: Data sharing in clinical research is critical for increasing knowledge discovery. Data and software tools should be FAIR: Findable, Accessible, Inter-operable and Re-usable. Many bottlenecks exist in the process of a clinical investigator using shared data including data acquisition and statistical analysis. The objective of this project is to develop a structure for sharing data and providing rapid automated statistical analysis through creation of a pre-packaged, open-source software container.

Methods: We use the open source software container technologies VirtualBox and Vagrant to create a template for sharing clinical data and analysis scripts as a single container. We use …

Rationale And Methods Of The Study Protocol: Streptococcus Pneumoniae Serotypes In Adults 18 Years And Older With Radiographically-Confirmed Community-Acquired Pneumonia (Cap), Ronika Alexander, Paula Peyrani, Julio A. Ramirez, Wesley H. Self Md, Mph, Carlos Grijalva, Francis Counselman, Gregory A. Volturo, Heidi Kabler, Luis Ostrosky-Zeichner, Richard Wunderink, Robert L. Sherwin, Senen Pena, Thomas File, Timothy L. Wiemken, Sharon Gray, Michael Pride, Kimbal D. Ford, Qin Jiang, Raul Isturiz

The University of Louisville Journal of Respiratory Infections

This study was an active, prospective surveillance study of adults 18 years and older hospitalized with community-acquired pneumonia (CAP) due to Streptococcus pneumoniae conducted at 21 hospitals in ten cities across the United States. This report describes the surveillance methodology applied between October 7, 2013 and September 30, 2016, including the identification and description of surveillance areas and populations at-risk for CAP hospitalization for estimation of incidence rates for selected study sites.

Streptococcus Pneumoniae Antigen, Missing Opportunities Of A Promising Point Of Care Diagnostic Test, Magdelina Słomka, Ruby Gupta, Baltej Singh, Venkatesh Gondhi, Siddartha Bhandary, Ekezie Francis, Jose Bordon

The University of Louisville Journal of Respiratory Infections

Background: The etiologic diagnosis of community acquired pneumonia (CAP) and community-acquired meningitis (CAM) are still far from optimal accuracy and turnaround time. The most common bacterial pathogen identified in both CAP and CAM is Streptococcus pneumoniae.

Methods: We reviewed the literature on S. pneumoniae antigen to highlight opportunities to optimize its use as a point of care diagnostic test to maximize quality of patient care, antimicrobial stewardship outcomes and cost saving. A PubMed search was performed using key words “S. pneumoniae antigen; rapid diagnostic tests for S. pneumoniae”. We selected articles in English and sorted into randomized …

Level Of Recall Bias Regarding Pneumococcal Vaccination History Among Adults Hospitalized With Community-Acquired Pneumonia: Results From The University Of Louisville Pneumonia Study, Sarah Van Heiden, Ruth Carrico, Timothy L. Wiemken, Ronika Alexander, John M. Mclaughlin, Qin Jiang, Paula Peyrani, William A. Mattingly, Stephen P. Furmanek, Connor L. English, Senen Pena, Raul Isturiz, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

Background: Recall bias is likely to occur in vaccine effectiveness studies using self-reported vaccination history. The validity of patient-reported vaccination status for adults is not well defined. The objective of this study was to evaluate the validity of self-reported pneumococcal vaccination history among patients hospitalized with community-acquired pneumonia (CAP).

Methods: Prospective ancillary study of a population-based observational study of hospitalized patients with CAP in the city of Louisville. To be included in the analysis, patients had to (i) be reached by phone 30-days after discharge from the hospital and (ii) report that they remembered whether or not they received a …

One-Year Mortality In Patients With Community-Acquired Pneumonia, Paula Peyrani, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

Pneumonia remains a common cause of morbidity and mortality in the US. Although, communityacquired pneumonia (CAP) has traditionally been considered an acute process, more recently, data have emerged showing that patients surviving an episode of CAP are at increased risk of death long after hospital discharged. In this descriptive review, we examine the current knowledge of long-term mortality and propose a hypothesis explaining the pathogenesis of long-term mortality in patients with CAP.

Maximizing Efficiency In Managing Nursing And Other Student Rotations: Lvhn Case Study, Lissette Ortiz Bba, Margaret A. Hadinger Edd, Ms

Department of Education

No abstract provided.

The Contribution Of Technology To The Development And Sustainability Of An Occupational Therapy Community Of Learners In Doctoral Education, Susan Toth-Cohen, Phd, Otr/L, Mary Gozza-Cohen, Phd, Sandra Schefkind, Otd, Otr/L, Faota

Department of Occupational Therapy Posters and Presentations

This case study describes the pivotal role of technology in developing a community of practice (COP) designed for post professional occupational therapists that enabled doctoral students, alumni and faculty to share information and insights about topics, initiatives and research critical to the Occupational Therapy field. The COP evolved through ongoing development of the post-professional occupational therapy doctorate (PPOTD) program at Jefferson University in Philadelphia.

The conceptual foundation for the COP moved beyond an initial focus on course delivery to an emphasis on development, implementation, and sustainability of a vibrant learning community. Transformation of the COP was greatly facilitated through the …

Most Common Statistical Methodologies In Recent Clinical Studies Of Community-Acquired Pneumonia, Stephen Furmanek, Connor L. English, Thomas Chandler, Timothy L. Wiemken Phd

The University of Louisville Journal of Respiratory Infections

Background: Training new individuals in pneumonia research is imperative to produce a new generation of clinical investigators with the expertise necessary to fill gaps in knowledge. Clinical investigators are often intimidated by their unfamiliarity with statistics. The objective of this study is to define the most common statistical methodologies in recent clinical studies of CAP to inform teaching approaches in the field.

Methods: Articles met inclusion criteria if they were clinical research with an emphasis on incidence, epidemiology, or patient outcomes, searchable via PubMed or Google Scholar, published within the timeframe of January 1st 2012 to August 1st 2017, …

Cyclic Peptide Conjugate Of Curcumin And Doxorubicin As An Anticancer Agent, Shaban Darwish, Saghar Mozaffari, Keykavous Parang, Rakesh Tiwari

Pharmacy Faculty Articles and Research

The hydrophobicity of curcumin creates hurdle towards its use in the anticancer therapy. Herein, we synthesized a curcumin-doxorubicin conjugated cyclic peptide scaffold to improve the solubility of curcumin and create a conjugate containing two anticancer agents. A solid-phase Fmoc/tBu solid phase methodology was used to synthesize a cell-penetrating nuclear targeting peptide with free thiol and amine groups, which was coupled with the activated doxorubicin (Dox) and curcumin, affording Dox-peptide-curcumin conjugate (DPCC) (10). The antiproliferative activity of the conjugate was evaluated in human leukemia carcinoma cell (CCRF-CEM), human ovarian carcinoma cell (SKOV-3), and normal kidney cell line (LLCPK). Cyclic peptide-doxorubicin conjugate …