Medicine and Health Sciences Commons^™

Rapid Evidence Assessment: Quality Of Studies Assessing Interventions To Support Fgm/C Abandonment, Tammary Esho, Jamlick Karumbi, Carolyne Njue

Reproductive Health

The last decade has seen increased focus and investment in interventions to eliminate female genital mutilation/cutting (FGM/C), along with the need to accelerate its abandonment. The UK Department for International Development (DFID) commissioned the Evidence to End FGM/C: Research to Help Girls and Women Thrive project to: 1) assess the quality of studies that have evaluated different interventions for the prevention of FGM/C, and 2) describe the FGM/C interventions that were evaluated by high-quality studies. The quality of evidence on the effectiveness and impact of FGM/C interventions is generally moderate to low. In addition, few baseline surveys are conducted prior …

Reducing Barriers To Accessing Fistula Repair: Establishing A Baseline In Ebonyi, Population Council

Reproductive Health

As a partner on the Fistula Care Plus (FC+) project, the Population Council is conducting implementation research that tests solutions to treatment barriers. Formative research in Nigeria’s Ebonyi State found that a lack of knowledge among lower-level providers and women and families of how the condition occurs, where treatment is available, and the signs and symptoms of obstetric fistula, as well as transportation costs, affect women’s access to screening and repair. Baseline data reveal the necessity of a comprehensive intervention to address fistula treatment barriers in Ebonyi. Not only do primary healthcare providers lack adequate knowledge of fistula, referral, and …

Reducing Barriers To Accessing Fistula Repair: Establishing A Baseline In Katsina, Population Council

Reproductive Health

As a partner on the Fistula Care Plus (FC+) project, the Population Council is conducting implementation research that tests solutions to treatment barriers. Formative research in Nigeria’s Katsina State found that a lack of knowledge among lower-level providers and women and families of how the condition occurs, where treatment is available, and the signs and symptoms of obstetric fistula, as well as transportation costs, affect women’s access to screening and repair. Baseline data reveal the necessity of a comprehensive intervention to address fistula treatment barriers in Katsina. Not only do primary healthcare providers lack adequate knowledge of fistula, referral, and …

Reducing Barriers To Accessing Fistula Repair: Establishing A Baseline In Uganda, Population Council

Reproductive Health

As a partner on the Fistula Care Plus (FC+) project, the Population Council is conducting implementation research that tests solutions to treatment barriers. Formative research in Uganda found that a lack of knowledge among lower-level providers and women and families of how the condition occurs, where treatment is available, and the signs and symptoms of obstetric fistula, as well as transportation costs, affect women’s access to screening and repair. Baseline data reveal the necessity of a comprehensive intervention to address fistula treatment barriers in Uganda. Not only do primary healthcare providers lack adequate knowledge of fistula, referral, and counseling, but …

Resilience And Community Response To Climate-Related Events: Case Studies From Four Countries, Aviva Klein Meyers, Karen Hardee

Reproductive Health

It is important for governments, aid organizations, and researchers to understand how developing communities respond to climate change and how their efforts can be improved within a framework of resilience thinking. This review explores the definition of resilience and, more specifically, community resilience and its components, then presents four case studies of community response to extreme weather events to illustrate community resilience in action. The review is intended to provide context for and inform more detailed exploration of community resilience in integrated programming (specifically, programming designed to improve health, environment, and population outcomes). It is also intended to capture references …

Results From Systematic Literature Review On Pe/E In Bangladesh, Karen Kirk, Amy Dempsey

Reproductive Health

By 2015, at the conclusion of the Millennium Development Goals, Bangladesh had achieved a reduction in maternal death from 550 per 100,000 live births in 1990, to 170 maternal deaths per 100,000 live births in 2015. Despite this progress, there are still between 5,000 and 6,000 maternal deaths every year in Bangladesh, where 20 percent are the result of pre-eclampsia and eclampsia (PE/E). This systematic review of peer-reviewed literature published between January 2000 and July 2016 identified interventions adopted to manage PE/E throughout Bangladesh. Specifically, it looked at issues around quality of care, gaps in the evidence, and barriers to …

Results From Systematic Literature Review On Pe/E In Nigeria, Amy Dempsey, Karen Kirk

Reproductive Health

Pre-eclampsia and eclampsia (PE/E), hypertensive disorders of pregnancy, are consistently cited as a leading cause of maternal and newborn morbidity and mortality in Nigeria. A recent, nationwide cross-sectional survey found that PE/E contributes to 28.2 percent of national maternal deaths. The other main contributors to maternal mortality are hemorrhage and pregnancy-related infection or sepsis. To fully understand the key challenges, gaps, and interventions related to the prevention and treatment of PE/E, the Ending Eclampsia project conducted a systematic review of papers on PE/E in Nigeria published between 2000–15. The methods, results, and recommendations are discussed in this brief.

Workplace Health And The Garment Sector In Cambodia, Bunmey Yat, Carolyn Rodehau, David Wofford, Ashish Bajracharya

Reproductive Health

In Cambodia, there has been considerable investment in improving the well-being of factory workers. Understanding the key stakeholders and their roles in improving worker health is essential for policy change and ensuring that interventions achieve sustainable, long-term impact in and around the workplace. This policy brief presents selected findings from a stakeholder and situational analysis undertaken by the Cambodia Worker Health Coalition (WorkerHealth) to understand the stakeholder landscape and policy environment for women’s health in the garment industry in Cambodia, with the objective of identifying leading stakeholders and their relationships, as well as strategies and opportunities for collaboration. Collaboration and …

Uganda Retail Audit: Analysis And Report, The Evidence Project

Reproductive Health

This brief presents results of a retail audit, carried out in January 2016, that was commissioned as part of PATH’s work under the USAID-funded Evidence Project to conduct a landscape assessment of the feasibility of a Total Market Approach (TMA) in Uganda. This project also involved key informant interviews with stakeholders on their attitudes toward TMA principles and the collection of a Uganda Market Research Summary of existing family planning knowledge. The approach is based on an understanding that equitably meeting the diverse needs of different population segments requires increased coordination across sectors, including the public, private for-profit, and not-for-profit …

Pantothenate Kinase-Associated Neurodegeneration, Khalid Hundallah, Afnan Al Hakeem

Neurosciences

No abstract provided.

Autoimmune Disease Presenting As Acute Abdomen, Wasim A Memon, Saad Siddiqui, Ameer Hamza

Department of Radiology

Mesenteric vasculitis and resultant bowel ischemia is rare but serious complication of autoimmune disorders. Early detection and treatment is the key to avoid potentially fatal outcomes of bowel perforation and peritonitis. In this series, we present patients presenting with acute abdominal pain and having CT imaging features of bowel ischemia who responded well to immunosuppressive therapy. The aim of this work is to familiarize health professionals with possibility and imaging features of mesenteric vasculitis.

The Social Validity Of Telepractice Among Spanish-Speaking Caregivers Of English Learners: An Examination Of Moderators, Lisa Fitton, Kristina N. Bustamante, Carla Wood

Faculty Publications

The purpose of the present paper was to examine the social validity of telepractice as a service delivery model for Spanish-speaking families of English learners. Quantitative survey methodology was employed to examine 79 caregivers' opinions regarding telepractice and to obtain background information about participants' home environments. Findings revealed that approximately 46% of the participant sample reported being interested in their children receiving services via telepractice. Caregivers reported limited familiarity with telepractice as an option, but were likely to express interest if their child had an identified speech or language disorder or if they were interested in increased access to Spanish …

Impact Of Aquaporin (Aqp1 And Aqp4) Genetic Variation On The Relationship Between Sleep Quality And Alzheimer’S Disease Pathological Hallmarks, Gavin Noel Mazzucchelli

Theses : Honours

Alzheimer’s disease (AD) is widely recognised as a growing global health issue with far ranging social and economic implications. The accumulation of Amyloid-β (Aβ) in the brain is a pathological hallmark of AD. A recently discovered lymphatic–like system in the central nervous system (termed the glymphatic system) has been postulated to be both implicit in the clearance of Aβ from the brain, and most effective during sleep—making sleep an important consideration in the investigation of AD. Central nervous system expressed water channel proteins, namely Aquaporin 1 and 4, have been suggested to play a pivotal role in glymphatic function and …

Contraceptive Use Among African Caribbean And African American Women With History Of Intimate Partner Violence, Desiree R. Bertrand

MUSC Theses and Dissertations

There is a paucity of research on contraceptive use among women experiencing intimate partner violence (IPV). Several factors may influence contraceptive use in this population, including cultural background, geographical location, and timing of IPV experience. However, current studies on contraceptive use among women with IPV histories are not focused on minority populations, particularly African Caribbean and African American women who have a higher incidence of IPV. This dissertation compendium addresses that research gap. The compendium includes three manuscripts: A scoping review, an integrative review, and the dissertation study, using data obtained from a multi-site study using a case (women experiencing …

Machine Safety: Hands-On Experimentation With Risk Estimation Parameters And Tools, François Gauthier, Yuvin Chinniah, Damien Burlet-Vienney, Barthélemy Aucourt, Stéphane Larouche

Rapports de recherche scientifique

Dans une démarche d’appréciation du risque telle que définie dans la norme internationale ISO 12100:2010, l’estimation du risque est une étape essentielle permettant aux concepteurs et aux utilisateurs de machines de déterminer le niveau de risque et les situations dangereuses les plus critiques. Deux études antérieures financées par l'Institut de recherche Robert-Sauvé en santé et en sécurité du travail (IRSST) ont permis de révéler que les nombreux outils qui permettent de réaliser l’estimation du risque se présentent sous des formes très diverses, et que plusieurs de leurs caractéristiques (ex. : paramètres, architecture) pouvaient influencer de façon importante le …

Development Of A Confined Space Risk Analysis And Work Categoraziation Tool, Yuvin Chinniah, Ali Bahloul, Damien Burlet-Vienney, Brigitte Roberge

Rapports de recherche scientifique

Au Québec, le Règlement sur la santé et la sécurité du travail (RSST) définit un espace clos à l’article 1 (ce projet a été mené avec la définition d’un espace clos applicable en 2016. Cette définition a été modifiée le 25 juillet 2023). Le travail en espace clos est une problématique qui concerne à la fois les secteurs municipal, manufacturier, chimique, militaire, agricole, de la construction et du transport. Les espaces clos parmi les plus courants en industrie sont les réservoirs, les silos, les cuves, les puits d’accès, les fosses, les égouts, les …

Design Of Horizontal Lifeline Systems For Fall Protection: Update Of Technical Guide, Bertrand Galy, André Lan

Rapports de recherche scientifique

Les chutes de hauteur sont encore aujourd’hui une des causes majeures d’accidents du travail. Trop souvent, les travailleurs ne s’attachent pas, faute de point d’ancrage disponible, ou parce qu’ils trouvent que les points d’attache fixes restreignent trop leurs mouvements. Cette restriction peut toutefois être levée grâce aux systèmes de corde d’assurance horizontale (SCAH). Le présent rapport constitue la mise à jour du guide technique T-18 publié en 1991 et rend ce dernier caduc. Cette mise à jour était devenue nécessaire à la suite de l’introduction, en 2001, au Code de sécurité pour les travaux de construction (CSTC), de l’obligation d’équiper …

Cyclic Ac253, A Novel Amylin Receptor Antagonist, Improves Cognitive Deficits In A Mouse Model Of Alzheimer’S Disease, Rania Soudy, Aarti Patel, Wen Fu, Kamaljit Kaur, David Mactavish, David Westaway, Rachel Davey, Jeffrey Zajac, Jack Jhamandas

Pharmacy Faculty Articles and Research

Introduction: Amylin receptor serves as a portal for the expression of deleterious effects of amyloid b-protein (Ab), a key pathologic hallmark of Alzheimer’s disease. Previously, we showed that AC253, an amylin receptor antagonist, is neuroprotective against Ab toxicity in vitro and abrogates Ab-induced impairment of hippocampal long-term potentiation.

Methods: Amyloid precursor protein–overexpressing TgCRND8 mice received intracerebroventricularly AC253 for 5 months. New cyclized peptide cAC253 was synthesized and administered intraperitoneally three times a week for 10 weeks in the same mouse model. Cognitive functions were monitored, and pathologic changes were quantified biochemically and immunohistochemically.

Results: AC253, when administered …

Nurse Educators’ Perceptions Of Using High-Fidelity Simulation In Teaching, Marlene Whigham

Theses and Dissertations

Nurse Educators’ Perceptions of Using High-Fidelity Simulation in Teaching. Marline Whigham, 2017: Applied Dissertation, Nova Southeastern University, Abraham S. Fischler College of Education. Keywords: nursing education, learning strategies, simulation, staff development, teaching styles.

High-fidelity simulation in nursing refers to the use of computerized manikins to offer realistic hands-on training to nursing students. The problem addressed by this dissertation was resistance among some faculty to the use of new computerized simulation technology in the nursing curriculum. The research question for this case study investigated how faculty members can incorporate simulation into the curriculum and barriers faced in setting the stage for …

Effect Of Harvest Method And Ammoniation On Digestibility And Intake Of Corn Residue, Ashley C. Conway, Tasha M. King, Melissa L. Jolly-Breithaupt Breithaupt, Jim C. Macdonald, Terry J. Klopfenstein, Mary E. Drewnoski

Nebraska Beef Cattle Reports

The effects of three harvest methods, both with and without ammonia treatment, on the in vivo digestibility and intake of baled corn residue were assessed in a digestion trial with lambs. Treatments included three corn residue harvest methods (conventional rake and bale, New Holland Cornrower™ with eight rows or with two rows of corn stalks chopped into the windrow containing the tailings [leaf, husk and upper stalk] from eight harvested rows) and the effects of ammoniation at 5.5% of DM compared to no ammoniation of the residue. Th e 2- Row baled residue (51.7%) had greater dry matter digestibility than …

Methods To Increase Productivity Of Spring Calving Production Systems In The Nebraska Sandhills, Devin Broadhead, L. A. Stalker, Jacki A. Musgrave Musgrave, Rick N. Funston

Nebraska Beef Cattle Reports

Feeding supplement to cattle grazing dormant winter range increased cow BW and BCS and calf performance, but not pregnancy rate. Using a CIDR to shorten the post-partum interval in a cow herd with existing acceptable reproductive performance did not improve pregnancy rate. Feeding creep feed to calves increased weaning BW but should be considered within the context of a cost/benefit analysis. Additional years of data collection may be necessary to draw definitive conclusions.

Predicting Feedlot Growth Performance Over The Feeding Period Utilizing Steer Age And Body Weight, Curtis J. Bittner, Andrea K. Watson, Jim C. Macdonald Donald, Galen E. Erickson

Nebraska Beef Cattle Reports

A pooled- analysis of UNL feedlot pens examined the effects of steer age and body weight on feedlot growth performance. For data analysis, pens were divided into 3 subclasses based on steer age (calf- fed, short yearling, or long yearling) and, grouped based upon initial body weight (500 to 1200 lb, in 100 lb increments) within each age class. As initial body weight increased, DMI (lb/d) for the whole feeding period increased quadratically in calf-fed steers and increased linearly in short and long yearlings. A quadratic increase in ADG was observed in calf- feds as initial body weight increased. No …

Acknowledgements

Nebraska Beef Cattle Reports

Appreciation is expressed to the following firms, associations, or agencies who provided grant support for research in the beef cattle program.

Agriculture and Food Research Initiative Competitive Grant/ USDA/NIFA Foundation Program: Animal Reproduction

The Beef Checkoff , Centennial, Colo

Cargill Corn Milling, Blair, Neb.

CSIRO, Commonwealth Scientific and Industrial Research Organization, Dickson, ACT, Australia

Elanco Animal Health, Indianapolis, Ind.

Huvepharma Inc. Peachtree City, GA

Dr. Kenneth and Caroline McDonald Eng Foundation San Antonio, Tex.

Lallemand Animal Nutrition. Montreal, Quebec, Canada

Merck Animal Health, Madison, NJ

National Cattlemen’s Beef Association, Centennial, Colo.

Effect Of Harvest Method On Digestibility Of Corn Residue, Tasha M. King, Melissa L. Jolly-Breithaupt, Jana L. Gramkow Gramkow, Terry J. Klopfenstein, Jim C. Macdonald

Nebraska Beef Cattle Reports

Corn residues can be an economical forage source for producers and advanced harvest methods have increased the quality of baled residue. A digestion study was conducted to evaluate the effects of harvest method of corn residues (low- stem, highstem, and conventional) on digestibility in lambs. Samples from total fecal collection were dried 1 of 3 ways to determine effects on digestibility estimates. Corn residue containing low- stem had greatest overall digestibility with high- stem residue being intermediate and conventional harvesting having the lowest digestibility. Drying method had no effect on digestibility estimates.

Comparison Of Titanium® 5 Ph- M Versus Titanium® 5 Plus Nuplura® Ph With The Presence Or Absence Of Monensin On Health And Performance Of Newly Received Feedlot Calves Fed Ramp®, Robert M. Jones, Curtis J. Bittner, F. Henry Hilscher Hilscher, Mallorie F. Wilken, Rick Stock, Galen E. Erickson

Nebraska Beef Cattle Reports

A receiving study was conducted to evaluate the effects of RAMP® with Rumensin® concentration (0 or 25.0 g/ton) given with one of two viral vaccinations (Titanium® 5 PH- M or Titanium® 5 plus NUPLURA® PH) on steer growth performance and morbidity. There were no significant vaccine by diet interactions observed. Neither vaccine treatment nor Rumensin® level affected intake, gain, or feed conversion. Vaccine type did not affect first pull (P = 0.19) or second pull morbidity rates (P = 0.52). These findings suggest that neither vaccine type nor Rumensin® concentration had any effect on steer growth performance or morbidity rate.

Evaluation Of 0 Or 300 Mg Of Optaflexx® On Growth Performance And Carcass Characteristics Of Steers Fed To Different Degrees Of Finish, Robert M. Jones, Curtis J. Bittner, F. Henry Hilscher Hilscher, Mallorie F. Wilken, Galen E. Erickson

Nebraska Beef Cattle Reports

A feedlot study evaluated the effects of ractopamine hydrochloride (Optaflexx®) dosage (0 or 300 mg/steer daily) and days on feed (118, 139, 160, 174 DOF) as a 2 × 3 + 1 factorial (steers fed 174 d were not fed Optaflexx) on performance of big yearlings. No interaction was observed between Optaflexx and days on feed. Feeding Optaflexx improved live final BW, carcass- adjusted ADG, carcass- adjusted feed conversion, and calculated yield grade. Increasing days on feed linearly increased live final BW, carcass-adjusted feed conversion, HCW, dressing percent, and marbling score but not ADG. Furthermore, a quadratic increase in LM …

Corn Residue Quality Throughout The Grazing Season, Shelby E. Gardine, Gavin L. Harsh, Robert G. Bondurant Bondurant, Jana L. Gramkow, Andrea K. Watson, Terry J. Klopfenstein

Nebraska Beef Cattle Reports

Changes in in vitro organic matter digestibility and digestible organic matter of corn residue were evaluated throughout the fall grazing and spring grazing seasons. In vitro organic matter digestibility and digestible organic matter were greatest at the beginning of fall grazing and declined over time. Slight weathering resulted in lower quality corn residue available at the beginning of spring grazing compared to the beginning of fall grazing. The in vitro organic matter digestibility of available residue declined 21% over the fall grazing season and 51% throughout the spring grazing season. As the availability of nutrients declines over time, adjustments in …

Perceptions Of Crop Consultants And Producers On Grazing Corn Residue In Nebraska, Jordan L. Cox, Kristen M. Ulmer, Manir Rakkar Rakkar, Lisa Franzen-Castle, Humberto Blanco-Canqui, Mary Drewnoski, Jim C. Macdonald, Richard J. Rasby

Nebraska Beef Cattle Reports

A survey was conducted to explore factors influencing corn residue grazing recommendations by crop consultants and producer practices in Nebraska. Approximately 80% of consultants recommended grazing corn residue, while 63% of producers allowed grazing. Of producers who did not graze, about 50% cited concerns related to soil compaction, inconvenience (lack of water, fencing, and land/equipment damage), and lack of access to livestock. Producers who allowed and consultants who recommended grazing were more likely to perceive that grazing residue increased subsequent grain yields. Most consultants (56.0%) and producers (43.8%) reported making decisions in regards to grazing based on their own observation. …

Pooled Gain Analysis Of Steers Grazing Corn Residue And Supplemented With Distillers Grains, Cody A. Welchons, Jim C. Macdonald

Nebraska Beef Cattle Reports

A pooled analysis combined data from three trials in which steer calves grazing corn residue were supplemented with distillers grains at varying amounts as a percent of BW. A regression equation was calculated in order to provide an accurate estimate of gain for calves fed distillers grains at various rates. Steers supplemented with distillers grains in a range from 0.3 to 1.1% of BW (1.5 to 6.5 lb / steer daily) had estimated gains that ranged from 1.07 to 1.94 lb / d. Th is prediction equation provides an estimate of gain for calves supplemented with distillers grains at various …

Effect Of Feeding Field Peas On Fresh Beef Quality, Hope R. Voegele, Katherine I. Domenech, Emery K. Kunze Kunze, Felipe A. Ribeiro, Karla H. Jenkins, Jim C. Macdonald, Chris R. Calkins

Nebraska Beef Cattle Reports

Th is study was conducted over two years to evaluate the use of field peas during two phases of production (grazing and finishing) on overall fresh beef quality. The backgrounding treatments included: no supplement, field peas, or dry- rolled corn and finishing treatments included the presence or absence of field peas. Loin samples (n = 232) were aged for 14 d and placed under retail display conditions for 7 d. Dietary treatments had no effect on tenderness (WBSF or SSF) or visual discoloration and minimal effects on objective color, lipid oxidation and fatty acid composition. These data indicate field peas …