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2017

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Articles 11191 - 11220 of 14524

Full-Text Articles in Medicine and Health Sciences

Understanding The Lives Of Adolescents And Young Adults (Udaya) In Uttar Pradesh, India (2015–16), K.G. Santhya, Rajib Acharya, Neelanjana Pandey, Ashish Kumar Gupta, Shilpi Rampal, Santosh Kumar Singh, A.J. Francis Zavier Jan 2017

Understanding The Lives Of Adolescents And Young Adults (Udaya) In Uttar Pradesh, India (2015–16), K.G. Santhya, Rajib Acharya, Neelanjana Pandey, Ashish Kumar Gupta, Shilpi Rampal, Santosh Kumar Singh, A.J. Francis Zavier

Poverty, Gender, and Youth

The goal of the program of research titled “Understanding the lives of adolescents and young adults (UDAYA) in Bihar and Uttar Pradesh” is to establish the levels, patterns, and trends in the situation of younger (10–14) and older (15–19) adolescents and to assess factors that influence the quality of transitions they make. The study is designed to provide robust insights on how investments in adolescents influence their life course by the time they reach young adulthood; enable evidence-based decisions on the types of programs worthy of scale-up; and furnish important baseline indicators against which the long-term impact of programs can …


Understanding The Lives Of Adolescents And Young Adults (Udaya): Bihar, Population Council Jan 2017

Understanding The Lives Of Adolescents And Young Adults (Udaya): Bihar, Population Council

Poverty, Gender, and Youth

Understanding the lives of adolescents and young adults (UDAYA) is a program of research conducted by the Population Council which seeks to: explore the situation and needs of younger (10−14 years) and older (15−19 years) adolescents; describe changes in their situation and needs over time; and assess factors that determine the quality of their transitions from adolescence to young adulthood. UDAYA, implemented from 2015 to 2020, uses community-based repeated cross-sectional surveys, panel surveys, and qualitative methods. With its geographical focus on Bihar and Uttar Pradesh, in India, UDAYA illustrates the lives of every fourth adolescent in that country and every …


Effect Of Sequence Of Simulated And Clinical Practicum Learning Experiences On Clinical Competency Of Nursing Students, Jamie Hansen, Marilyn Bratt Jan 2017

Effect Of Sequence Of Simulated And Clinical Practicum Learning Experiences On Clinical Competency Of Nursing Students, Jamie Hansen, Marilyn Bratt

College of Nursing Faculty Research and Publications

Two different sequences of blocks of simulated and clinical practicum learning experiences compared the clinical competency development of nursing students using a randomized crossover design. Competency was measured 3 times: after each block of simulated and clinical experiences and after a final simulated experience. No significant differences in competency scores between the 2 groups across the 3 time points were found. Using alternative models of clinical and simulation learning may help address barriers to the delivery of clinical education faced by schools of nursing


Discharge Teaching, Readiness For Discharge, And Post-Discharge Outcomes In Parents Of Hospitalized Children, Marianne E. Weiss, Kathleen Sawin, Karen Gralton, Norah L. Johnson, Carol Klingbeil, Stacee M. Lerret, Shelly Malin, Olga Yakusheva, Rachel Schiffman Jan 2017

Discharge Teaching, Readiness For Discharge, And Post-Discharge Outcomes In Parents Of Hospitalized Children, Marianne E. Weiss, Kathleen Sawin, Karen Gralton, Norah L. Johnson, Carol Klingbeil, Stacee M. Lerret, Shelly Malin, Olga Yakusheva, Rachel Schiffman

College of Nursing Faculty Research and Publications

Purpose

This study explored the sequential relationships of parent perceptions of the quality of their discharge teaching and nurse and parent perceptions of discharge readiness to post-discharge outcomes (parental post-discharge coping difficulty, readmission and emergency department visits).

Design/methods

In this secondary analysis of data from a longitudinal pilot study of family self-management discharge preparation, the correlational design used regression modeling with data from a convenience sample of 194 parents from two clinical units at a Midwest pediatric hospital. Data were collected on the day of discharge (Quality of Discharge Teaching Scale; Readiness for Hospital Discharge Scale), at 3 weeks post-discharge …


Rankings Matter: Nurse Graduates From Higher-Ranked Institutions Have Higher Productivity, Olga Yakusheva, Marianne E. Weiss Jan 2017

Rankings Matter: Nurse Graduates From Higher-Ranked Institutions Have Higher Productivity, Olga Yakusheva, Marianne E. Weiss

College of Nursing Faculty Research and Publications

Background

Increasing demand for baccalaureate-prepared nurses has led to rapid growth in the number of baccalaureate-granting programs, and to concerns about educational quality and potential effects on productivity of the graduating nursing workforce. We examined the association of individual productivity of a baccalaureate-prepared nurse with the ranking of the degree-granting institution.

Methods

For a sample of 691 nurses from general medical-surgical units at a large magnet urban hospital between 6/1/2011–12/31/2011, we conducted multivariate regression analysis of nurse productivity on the ranking of the degree-granting institution, adjusted for age, hospital tenure, gender, and unit-specific effects. Nurse productivity was coded as “top”/“average”/“bottom” …


Nursing Students’ Perception Of The Stigma Of Mental Illness, Abir K. Bekhet, Carolyn J. Murrock, Qiyan Mu, Harpreet Singh-Gill Jan 2017

Nursing Students’ Perception Of The Stigma Of Mental Illness, Abir K. Bekhet, Carolyn J. Murrock, Qiyan Mu, Harpreet Singh-Gill

College of Nursing Faculty Research and Publications

Background: Mental health disorders are highly prevalent in the U.S. Nursing students’ perceptions regarding the stigma of mental illness will impact the quality of care delivered and the patients’ outcomes.

Method: Data was collected from 64 sophomore students. Five open ended questions were distributed to the students during the first class. All the surveys were collected by a volunteer student and were placed in the instructor’s mailbox in a sealed envelope.

Results: The results revealed three categories: students ‘perceptions of the causes of mental illness stigmatization, their own perception of mental illness, and their perception on how to break the …


Development And Psychometric Evaluation Of The Nurses Professional Values Scale-3, Darlene Weis, Mary Jane Schank Jan 2017

Development And Psychometric Evaluation Of The Nurses Professional Values Scale-3, Darlene Weis, Mary Jane Schank

College of Nursing Faculty Research and Publications

Background and Purpose: The Nurses Professional Values Scale-3 (NPVS-3) is an instrument derived from the American Nurses Association Code designed to measure nurses' professional values. The purpose of this study was to examine its psychometric properties. Methods: A random sample of 1,139 baccalaureate nursing students, graduate nursing students, and practicing nurses participated. The 28-item Likert-scale instrument was subjected to exploratory and confirmatory factor analysis. Principal components analysis with varimax rotation and Kaiser normalization resulted in a 3-factor solution. Results: Findings supported internal consistency reliability of 3 factors with alpha coefficients from .80 to .91 and total scale coefficient of .94. …


Examining The Relationship Between Clinical Judgment And Nursing Actions In Prelicensure Students, Andrea Stuedemann Fedko, Kristina Dreifuerst Jan 2017

Examining The Relationship Between Clinical Judgment And Nursing Actions In Prelicensure Students, Andrea Stuedemann Fedko, Kristina Dreifuerst

College of Nursing Faculty Research and Publications

Faculty frequently use the Lasater Clinical Judgment Rubric (LCJR) to identify students’ clinical judgment; however, it is unclear whether LCJR scores relate to appropriate nursing action. In a pilot study consisting of senior-level nursing students (N = 22), participants were scored on the LCJR and anticipated nursing actions, and results were analyzed using simple linear regression. There was a statistically significant correlation (r = 0.364) between clinical judgment and nursing action. Results suggest that total LCJR scores may be an indicator of the completion of indicated nursing action.


Heart Disease And African Americans, Patricia Guy-Walls, Jody Long Jan 2017

Heart Disease And African Americans, Patricia Guy-Walls, Jody Long

Research, Publications & Creative Work

Good health depends on multiple factors, including financial status. Higher socioeconomic status correlates with a lower risk of cancer, diabetes, and heart disease. Lukachko, Hatzenbuehler, and Keyes (2014) stated that the advantages of income status make a difference with health, specifically heart disease. Another significant factor affecting heart disease is health care disparity. Kahng (2010) found that the accumulative impact of health care disparities experienced over a lifetime contributes to chronic stress and heart-related problems.

Despite advancement in care, more African Americans, compared with other racial groups, die from cardiovascular disease (Centers for Disease Control and Prevention [CDC], 2016). Several …


Time Related Effects On Functional Brain Connectivity After Serotonergic And Cholinergic Neuromodulation, Bernadet L. Klaassens, Serge A. Rombouts, Anderson M. Winkler, Helene C. Van Gorsel, Jeroen Van Der Grond, Joop M A Van Gerven Jan 2017

Time Related Effects On Functional Brain Connectivity After Serotonergic And Cholinergic Neuromodulation, Bernadet L. Klaassens, Serge A. Rombouts, Anderson M. Winkler, Helene C. Van Gorsel, Jeroen Van Der Grond, Joop M A Van Gerven

School of Medicine Publications

Psychopharmacological research, if properly designed, may offer insight into both timing and area of effect, increasing our understanding of the brain's neurotransmitter systems. For that purpose, the acute influence of the selective serotonin reuptake inhibitor citalopram (30 mg) and the acetylcholinesterase inhibitor galantamine (8 mg) was repeatedly measured in 12 healthy young volunteers with resting state functional magnetic resonance imaging (RS-fMRI). Eighteen RS-fMRI scans were acquired per subject during this randomized, double blind, placebo-controlled, crossover study. Within-group comparisons of voxelwise functional connectivity with 10 functional networks were examined (P < 0.05, FWE-corrected) using a non-parametric multivariate approach with cerebrospinal fluid, white matter, heart rate, and baseline measurements as covariates. Although both compounds did not change cognitive performance on several tests, significant effects were found on connectivity with multiple resting state networks. Serotonergic stimulation primarily reduced connectivity with the sensorimotor network and structures that are related to self-referential mechanisms, whereas galantamine affected networks and regions that are more involved in learning, memory, and visual perception and processing. These results are consistent with the serotonergic and cholinergic trajectories and their functional relevance. In addition, this study demonstrates the power of using repeated measures after drug administration, which offers the chance to explore both combined and time specific effects. Hum Brain Mapp 38:308-325, 2017. © 2016 Wiley Periodicals, Inc.


Women’S Narratives Of Living In Polygamous Marriages: Rural Malawian Experience Distilled And Preserved In Poetic Constructions, April Yerges, Patricia E. Stevens, Lucy Mkandawire-Valhmu, Wendy S. Bauer, Thokozani Mwenyekonde, Lance Weinhardt, Loren W. Galvao Jan 2017

Women’S Narratives Of Living In Polygamous Marriages: Rural Malawian Experience Distilled And Preserved In Poetic Constructions, April Yerges, Patricia E. Stevens, Lucy Mkandawire-Valhmu, Wendy S. Bauer, Thokozani Mwenyekonde, Lance Weinhardt, Loren W. Galvao

College of Nursing Faculty Research and Publications

Polygamy in sub-Saharan Africa has been linked to poverty, infant mortality, and HIV; however, it is unknown how interpersonal dynamics within polygamous households may influence population health outcomes. Findings from this postcolonial feminist study derive from interview data in a larger mixed-methods study in rural Malawi. We used thematic narrative analysis to probe 25 women's stories and applied an arts-based research technique, poetic construction, to present the results. Participants' evocative expressions, distilled and preserved in poetic form, illustrate themes of perseverance, grief, agency, and reflection. We discuss how gender relations, childrearing, tradition, economics, and health intersect in polygamous households.


Auditory Erp Differences Across A Continuum Of Psychotic Symptoms In Non-Clinical Population, Anaya Rehman Jan 2017

Auditory Erp Differences Across A Continuum Of Psychotic Symptoms In Non-Clinical Population, Anaya Rehman

Theses and Dissertations (Comprehensive)

Psychosis is a term given to a mental state described as a loss of contact with the real world. The aim of this thesis was to examine early non-specific psychotic experiences in a healthy population by means of two self-report screening tools: Prime Screen and Youth Psychosis At-Risk Questionnaire-Brief, and place individuals on a psychosis continuum. Across this psychosis continuum, three event related potential (ERP) components were assessed: P300, Mismatch Negativity and N100. There is evidence that P300 and mismatch negativity amplitudes diminish in individuals with psychosis. Similarly, impaired N100 amplitude suppression (increased N100 amplitudes) during vocalization has been observed …


Learning And Working Together: Invoking Systems’ Change Through Inter-Organizational Collaborative Principles And A Learning Community Framework, Brandon Hey Jan 2017

Learning And Working Together: Invoking Systems’ Change Through Inter-Organizational Collaborative Principles And A Learning Community Framework, Brandon Hey

Theses and Dissertations (Comprehensive)

Local communities face significant challenges such as increased inequality, immigration, and global climate change. In order to address these challenges whole cities have to innovate and learn together. In this thesis, I introduce the Learning Community (LC) model, a new way of collaborating and creating collective impact that emphasizes learning, alongside collective impact, as a central strategy to addressing complex social challenges. In a LC, members value the continuous pursuit of knowledge, feedback, and experimentation as well as the flow of information and resources between academic institutions and practice groups. The value of learning is built into key structures …


The Effect Of Twist On The Mechanical Properties Of The Intervertebral Disc, Maxine Harvey-Burgess Jan 2017

The Effect Of Twist On The Mechanical Properties Of The Intervertebral Disc, Maxine Harvey-Burgess

Theses and Dissertations (Comprehensive)

Introduction: Intervertebral disc (IVD) herniation is a common injury to the IVD and a frequent source of low back pain. IVD herniation occurs when the nucleus pulposus migrates through both the inter- and intralamellar matrices of the annulus fibrosus (AF). There are a number of mechanical risk factors associated with herniation, including repetitive flexion and twist. In vivo, twist combined with repetitive flexion has been associated with increased experience of low back pain and herniation. Additionally, in vitro, when repetitive flexion is combined with twist, IVD herniation occurs more easily than repetitive flexion alone. However, the mechanisms behind …


The Effects Of Orthotics And Increased Plantar Sole Mechanoreceptor Activation On Turning Performance In Individuals With Parkinson’S Disease, Kelly A. Robb Jan 2017

The Effects Of Orthotics And Increased Plantar Sole Mechanoreceptor Activation On Turning Performance In Individuals With Parkinson’S Disease, Kelly A. Robb

Theses and Dissertations (Comprehensive)

Locomotion and turning are complex movement patterns essential to activities of daily living. Individuals with Parkinson’s disease (PD) report difficulties turning, often coupled with impaired balance and increased fear of falling. The purpose of this within-subject study was to determine if orthotics, with and without a textured top cover, can improve gait stability and turning performance within Parkinson’s participants. Seven participants with a diagnosis of idiopathic Parkinson’s disease, aged 55-80 years old, participated in the study. Participants completed three testing sessions; baseline, 4 weeks post-baseline, and 5 weeks post-baseline. The ‘footwear only’ and ‘footwear + non-textured orthotic’ conditions were tested …


The Effects Of A 12-Week Custom Foot Orthotic Intervention On The Intrinsic Muscles Of The Foot, And Dynamic Stability During Unexpected Gait Termination In Healthy Young Adults, Katrina Protopapas Jan 2017

The Effects Of A 12-Week Custom Foot Orthotic Intervention On The Intrinsic Muscles Of The Foot, And Dynamic Stability During Unexpected Gait Termination In Healthy Young Adults, Katrina Protopapas

Theses and Dissertations (Comprehensive)

Introduction: Custom-made foot orthotics (CFO’s) are a commonly prescribed intervention to help individuals that are suffering from foot pain and foot disorders. However, the mechanisms of CFO’s are still poorly understood and are not well known. With the plantar intrinsic muscles of the foot being in direct contact with the CFO, it puts these structures at risk for disuse muscle atrophy as a result of being offloaded. Therefore, the purpose of the current study was to determine the effect of a 12-week custom-made foot orthotic intervention on the intrinsic muscles of the foot and dynamic stability during unexpected gait termination. …


Structure-Function Investigation Of Proteins Involved In Cellulose Biosynthesis By Escherichia Coli, Thomas Brenner Jan 2017

Structure-Function Investigation Of Proteins Involved In Cellulose Biosynthesis By Escherichia Coli, Thomas Brenner

Theses and Dissertations (Comprehensive)

Bacteria thrive within multicellular communities called biofilms consisting of a self-produced matrix. Biofilm matrices improve bacterial adherence to surfaces while creating a barrier from host immune responses, disinfectants, antibiotics and other environmental factors. Persistent colonization by the widely distributed pathogens, Escherichia coli and Salmonella spp., has been linked to production of biofilms composed of the exopolysaccharide cellulose. Cellulose-containing biofilms are also important to Acetobacter, Sarcina, Rhizobium and Agrobacterium species to form symbiotic and pathogenic interactions. In Enterobacteriaceae, two operons (bcsABZC and bcsEFG) are proposed to encode for proteins that form a cellulose biosynthetic complex that spans the …


A Case Of Spontaneous Transdiaphragmatic Intercostal Hernia With Contralateral Injury, And Review Of The Literature., Alexander A Chapman, Steven B Duff Jan 2017

A Case Of Spontaneous Transdiaphragmatic Intercostal Hernia With Contralateral Injury, And Review Of The Literature., Alexander A Chapman, Steven B Duff

Surgery Articles

This case report discusses the diagnosis and management of a 67-year-old male presenting with a spontaneous transdiaphragmatic intercostal hernia with contralateral intercostal hernia. The patient had a history of chronic obstructive pulmonary disease (COPD) exacerbations requiring multiple prolonged courses of steroids. The patient was ultimately diagnosed with computed tomography (CT) and underwent surgical repair via thoracotomy with primary repair of the diaphragmatic defect. The patient's postoperative course was uncomplicated. A review of the literature since the first similar case in 1977 recognizes the propensity of this injury to be found in patients with COPD and chronic steroid usage, as well …


Complete Mouth Rehabilitation And Gastroesophageal Reflux Disease: Conventional And Contemporary Treatment Approaches, Vasilios Chronopoulos, Georgios Maroulakos, Konstantinos Tsoutis, Panagiota Stathopoulou, William W. Nagy Jan 2017

Complete Mouth Rehabilitation And Gastroesophageal Reflux Disease: Conventional And Contemporary Treatment Approaches, Vasilios Chronopoulos, Georgios Maroulakos, Konstantinos Tsoutis, Panagiota Stathopoulou, William W. Nagy

School of Dentistry Faculty Research and Publications

This report describes the diagnosis and prosthodontic management of 2 patients with a history of chronic gastroesophageal reflux disease and worn dentition. Different treatment approaches were used for oral rehabilitation. Use of conventional and contemporary restorative materials resulted in functional and esthetic prosthodontic rehabilitation with a favorable prognosis.

Gastroesophageal reflux disease (GERD) is a “condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications." Reflux episodes can be intensified by dietary habits, smoking, physical exercise, and obstructive sleep apnea.Complications of GERD are regurgitation, chest pain, esophagitis, Barrett’s esophagus, esophageal adenocarcinoma, cough, asthma, and dental erosion.GERD is …


A Current Overview Of Materials And Strategies For Potential Use In Maxillofacial Tissue Regeneration, Hossein E. Jazayeri, Mohammadreza Tahriri, Mehdi Razavi, Kimia Khoshroo, Farahnaz Fahimipour, Erfan Dashtimoghadam, Luis Eduardo Almeida, Lobat Tayebi Jan 2017

A Current Overview Of Materials And Strategies For Potential Use In Maxillofacial Tissue Regeneration, Hossein E. Jazayeri, Mohammadreza Tahriri, Mehdi Razavi, Kimia Khoshroo, Farahnaz Fahimipour, Erfan Dashtimoghadam, Luis Eduardo Almeida, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Tissue regeneration is rapidly evolving to treat anomalies in the entire human body. The production of biodegradable, customizable scaffolds to achieve this clinical aim is dependent on the interdisciplinary collaboration among clinicians, bioengineers and materials scientists. While bone grafts and varying reconstructive procedures have been traditionally used for maxillofacial defects, the goal of this review is to provide insight on all materials involved in the progressing utilization of the tissue engineering approach to yield successful treatment outcomes for both hard and soft tissues. In vitro and in vivo studies that have demonstrated the restoration of bone and cartilage tissue with …


Development Of 3d Pcl Microsphere/Tio2 Nanotube Composite Scaffolds For Bone Tissue Engineering, Kimia Khoshroo, Tahereh S. Jafarzadeh Kashi, Fathollah Moztarzadeh, Mohammadreza Tahriri, Hossein E. Jazayeri, Lobat Tayebi Jan 2017

Development Of 3d Pcl Microsphere/Tio2 Nanotube Composite Scaffolds For Bone Tissue Engineering, Kimia Khoshroo, Tahereh S. Jafarzadeh Kashi, Fathollah Moztarzadeh, Mohammadreza Tahriri, Hossein E. Jazayeri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

In this research, the three dimensional porous scaffolds made of a polycaprolactone (PCL) microsphere/TiO2 nanotube (TNT) composite was fabricated and evaluated for potential bone substitute applications. We used a microsphere sintering method to produce three dimensional PCL microsphere/TNT composite scaffolds. The mechanical properties of composite scaffolds were regulated by varying parameters, such as sintering time, microsphere diameter range size and PCL/TNT ratio. The obtained results ascertained that the PCL/TNT (0.5 wt%) scaffold sintered at 60 °C for 90 min had the most optimal mechanical properties and an appropriate pore structure for bone tissue engineering applications. The average pore size …


Optimizing Anterior Implant Outcome Immediately After Implant Placement And Grafting By Using Patient’S Extracted Teeth: A Case Report, Soni Prasad, Jay Darryl Banez, Despoina Bompolaki, Yvonne Hart Jan 2017

Optimizing Anterior Implant Outcome Immediately After Implant Placement And Grafting By Using Patient’S Extracted Teeth: A Case Report, Soni Prasad, Jay Darryl Banez, Despoina Bompolaki, Yvonne Hart

School of Dentistry Faculty Research and Publications

Optimizing anterior implant outcome using patient’s extracted teeth.

Successful implant treatment in the anterior maxilla is predicated on providing a functional and esthetically acceptable outcome. As well, achieving a predictable ideal emergence profile and soft tissue contour is expected. Placing immediate provisional restorations utilizing the patient’s modified extracted teeth can facilitate initiate facial soft tissue contouring while precluding undue pressure on the surgical site during the early healing phase. This allows for a one stage surgical procedure, fixed provisionalization and ideal tissue contouring.

This clinical report presents the use of a patient’s modified extracted permanent teeth as bonded fixed provisional …


Immunohistochemical Analysis Of Il-1 Beta In The Discs Of Patients With Temporomandibular Joint Dysfunction, Luis Eduardo Almeida, Sean Pierce, Joseph Zacharias, William E. Cullinan, Lucia Noronha, Marcia Olandoski, Vinicius Tramontina, Carla Loreto, Rosalia Leonardi Jan 2017

Immunohistochemical Analysis Of Il-1 Beta In The Discs Of Patients With Temporomandibular Joint Dysfunction, Luis Eduardo Almeida, Sean Pierce, Joseph Zacharias, William E. Cullinan, Lucia Noronha, Marcia Olandoski, Vinicius Tramontina, Carla Loreto, Rosalia Leonardi

School of Dentistry Faculty Research and Publications

Purpose: Interleukin-1 beta (IL-1β) is a cytokine that participates in the regulation of immune responses and inflammatory reactions. It is hypothesized that IL-1 levels may be elevated in patients suffering from temporomandibular joint dysfunction. The purpose of this study was to determine the association of IL-1β expression with TMD using an immunohistochemical approach to evaluate the joint disc.

Materials and methods: A total of 39 human temporomandibular joint disc samples were collected, with 31 samples in the test group. Nineteen of the test group samples were from discs of patients with anterior disc displacement with reduction, and 12 …


Oral Examination, Alessandro Villa, Michael J. Wells, Drore Eisen, Jeff Burgess, James J. Nordlund, Denis P. Lynch, Gary L. Stafford Jan 2017

Oral Examination, Alessandro Villa, Michael J. Wells, Drore Eisen, Jeff Burgess, James J. Nordlund, Denis P. Lynch, Gary L. Stafford

School of Dentistry Faculty Research and Publications

The oral cavity is the first component of the digestive tract, which is delimited by the lips anteriorly and the oropharynx posteriorly. The oral cavity functions as a protective barrier and is an essential component for speech and swallowing, mastication, digestion, and taste sensation.

The oral examination comprises a uniform and consistent inspection of the head and neck and an intraoral evaluation of the hard and soft tissues (see the images below) in conjunction with a thorough medical and dental history. The entire mouth should be inspected regardless of the patient’s chief complaint and reasons for the visit. [1 …


The Relationships Between Fluoride Intake Levels And Fluorosis Of Late‐Erupting Permanent Teeth, Pradeep Bhagavatula, Alexandra Curtis, Barbara Broffitt, Karin Weber-Gasparoni, John J. Warren, Steven M. Levy Jan 2017

The Relationships Between Fluoride Intake Levels And Fluorosis Of Late‐Erupting Permanent Teeth, Pradeep Bhagavatula, Alexandra Curtis, Barbara Broffitt, Karin Weber-Gasparoni, John J. Warren, Steven M. Levy

School of Dentistry Faculty Research and Publications

Objectives

To examine the relationships between fluoride intake levels and fluorosis of late‐erupting permanent teeth.

Methods

The current study used information collected from 437 children in the longitudinal Iowa Fluoride Study. Participants' fluoride intake information was collected using questionnaires from birth to age 10 years. Estimated mean daily fluoride intake was categorized into low, moderate, and high intake tertiles for each age interval (2‐5, 5‐8, and 2‐8 years). Bivariate analyses were performed to study the relationships between self‐reported fluoride intake levels during three age intervals and dental fluorosis.

Results

For canines and second molars, the prevalence of mostly mild fluorosis …


Expression Of Interleukin-1 And Temporomandibular Disorder: Contemporary Review Of The Literature, Adam Sorenson, Kyle Hresko, Seth Butcher, Sean Pierce, Vinícius Augusto Tramontina, Rosalia Leonardi, Carla Loreto, Jose A. Bosio, Luis Eduardo Almeida Jan 2017

Expression Of Interleukin-1 And Temporomandibular Disorder: Contemporary Review Of The Literature, Adam Sorenson, Kyle Hresko, Seth Butcher, Sean Pierce, Vinícius Augusto Tramontina, Rosalia Leonardi, Carla Loreto, Jose A. Bosio, Luis Eduardo Almeida

School of Dentistry Faculty Research and Publications

Objective: Temporomandibular disorders (TMD) are a group of conditions affecting the temporomandibular joint (TMJ), leading to jaw dysfunction, joint and muscle pain, and a decrease in quality of life. A communication network of pro- and anti-inflammatory mediators called cytokines maintains the homeostasis of the TMJ. This review will focus on the Interleukin (IL) family of cytokines, which have been quantified in TMJ synovial fluids in a variety of studies. IL-1α and IL-1β have pro-inflammatory effects, while the endogenous receptor antagonist (IL-1RA) inhibits the pro-inflammatory effects of IL-1.

Methods: A literature search (2006–2016) to identify eligible studies was completed …


Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi Jan 2017

Evaluation Of Glycated Albumin (Ga) And Ga/Hba1c Ratio For Diagnosis Of Diabetes And Glycemic Control: A Comprehensive Review, Sara Yazdanpanah, Mohammad Rabiee, Mohammadreza Tahriri, Mojgan Abdolrahim, Asodollah Rajab, Hossein E. Jazayeri, Lobat Tayebi

School of Dentistry Faculty Research and Publications

Diabetes Mellitus (DM) is a group of metabolic diseases characterized by chronic high blood glucose concentrations (hyperglycemia). When it is left untreated or improperly managed, it can lead to acute complications including diabetic ketoacidosis and non-ketotic hyperosmolar coma. In addition, possible long-term complications include impotence, nerve damage, stroke, chronic kidney failure, cardiovascular disease, foot ulcers, and retinopathy. Historically, universal methods to measure glycemic control for the diagnosis of diabetes included fasting plasma glucose level (FPG), 2-h plasma glucose (2HP), and random plasma glucose. However, these measurements did not provide information about glycemic control over a long period of time. To …


Adults With Common Variable Immunodeficiency: A Singlecenter Experience, Uğur Haci̇ Muşabak, Fevzi̇ Demi̇rel, Sai̇t Yeşi̇lli̇k, Abdullah Baysan, Ali̇ Selçuk, Özgür Kartal, Mustafa Güleç, Çağatay Öktenli̇, Osman Şener Jan 2017

Adults With Common Variable Immunodeficiency: A Singlecenter Experience, Uğur Haci̇ Muşabak, Fevzi̇ Demi̇rel, Sai̇t Yeşi̇lli̇k, Abdullah Baysan, Ali̇ Selçuk, Özgür Kartal, Mustafa Güleç, Çağatay Öktenli̇, Osman Şener

Turkish Journal of Medical Sciences

Background/aim: In this study, we aimed to assess the clinical and immunological findings of our patients with common variable immunodeficiency (CVID). Materials and methods: We analyzed the records of 31 adult patients with CVID (12 females, 19 males). The patients were classified into clinical and immunophenotypic subgroups for statistical comparisons. Results: Our patients had some clinical signs in considerable frequencies, such as low body weight (45.2%), urinary tract infections (41.9%), various dermatoses (35.5%), and oral aphthae (32.3%). The histological findings in the biopsy specimens of the gastrointestinal tract (nodular lymphoid hyperplasia, villous atrophy, and lymphocytic infiltrates at mucosa) were significantly …


Transcription Factor 7-Like 2 (Tcf7l2) Gene Polymorphisms Are Strong Predictorsof Type 2 Diabetes Among Nonobese Diabetics In The Turkish Population, Dudu Erkoç Kaya, Hi̇lal Arikoğlu, Seyi̇t Ali̇ Kayiş, Onur Öztürk, Mustafa Sai̇t Gönen Jan 2017

Transcription Factor 7-Like 2 (Tcf7l2) Gene Polymorphisms Are Strong Predictorsof Type 2 Diabetes Among Nonobese Diabetics In The Turkish Population, Dudu Erkoç Kaya, Hi̇lal Arikoğlu, Seyi̇t Ali̇ Kayiş, Onur Öztürk, Mustafa Sai̇t Gönen

Turkish Journal of Medical Sciences

Background/aim: Type 2 diabetes (T2D) is a multifactorial disease, determined by environmental and genetic factors. Currently, the transcription factor 7-like 2 (TCF7L2) gene shows the strongest association with T2D. In this study, we investigated whether TCF7L2 gene polymorphisms are associated with T2D in a Turkish population. Materials and methods: Using PCR-RFLP and PCR-SSCP, we genotyped six intronic polymorphisms in the TCF7L2 gene, commonly associated with T2D, in 169 individuals with diabetes and 119 healthy controls. Results: We found that rs7903146 C -> T substitution in intron 3 (OR: 1.9, P = 0.005) and rs12255372 G -> T substitution in intron …


Pooled Analysis Of 899 Nosocomial Meningitis Episodes From Turkey, Oğuz Reşat Si̇pahi̇, Arzu Nazli Zeka, Meltem Taşbakan, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Tansu Yamazhan, Hi̇lal Si̇pahi̇, Sercan Ulusoy Jan 2017

Pooled Analysis Of 899 Nosocomial Meningitis Episodes From Turkey, Oğuz Reşat Si̇pahi̇, Arzu Nazli Zeka, Meltem Taşbakan, Hüsnü Pullukçu, Bi̇lgi̇n Arda, Tansu Yamazhan, Hi̇lal Si̇pahi̇, Sercan Ulusoy

Turkish Journal of Medical Sciences

Background/aim: Healthcare-associated meningitis (HCAM) is a relatively rare entity with significant morbidity and mortality. The aim of this study was to systematically review the Turkish medical literature for acute nosocomial meningitis. Materials and methods: One national (ULAKBİM) and two international (www.scopus.com and www.pubmed.com) databases were searched. In addition, abstracts of four national congresses held between 2004 and 2013 were searched for reports for HCAM meningitis. Results: Data for 899 HCAM meningitis episodes were obtained from 24 reports. In terms of clinical findings, 177 of 216 (81.9%) had fever (>38 °C), 55 of 64 (85.9%) had high CRP levels, 105 …