Medicine and Health Sciences Commons^™

The Stethoscoop, January 2017, Mennonite College Of Nursing

The Stethoscoop

The Stethoscoop is the newsletter for Mennonite College of Nursing students.

The Impact Of Stress On Steroid Hormones And Cue Reactivity In Smokers And Gamblers, Stephanie Elaine Wemm

Legacy Theses & Dissertations (2009 - 2024)

Addictions, both substance and behavioral, have been conceptualized as having similar biopsychosocial processes with different opportunistic expressions (Shaffer et al., 2004). Biological processes such as the hormonal response to stress as measured by cortisol, dehydroepiandrosterone (DHEA), and the ratio of the DHEA/cortisol may be among the variables underlying the disposition to develop an addictive disorder, regardless of whether it is a substance-based or a so-called behavioral addiction. The current study aimed to examine whether physiological and psychological reactions to stress are similar in high-frequency smokers and gamblers. The subjective (urges, cravings) and physiological responses (skin conductance and heart rate) of …

Mortality One-Year Post Stroke : What Matters? : An Exploratory Study Of A Cohort In New York State, Zainab Magdon-Ismail

Legacy Theses & Dissertations (2009 - 2024)

Background/Purpose: Stroke is one of the leading causes of mortality and serious long-term disability in the United States. However, there are few studies evaluating factors associated with long-term outcomes among stroke survivors.

Early Diagnosis And Intervention For Young Children With Autism Spectrum Disorder In New York State, Grace Esther Caroline Korompis

Legacy Theses & Dissertations (2009 - 2024)

This study examined the prevalence of autism spectrum disorder (ASD), analyzed the trends, assessed children’s sociodemographic characteristics and examined timing of ASD diagnosis among children who enrolled in the New York State Early Intervention Program (NYSEIP).

Impact Of Substance Use And Overweight Status On The Relationship Between Domestic Violence And Bullying, Marcie Fraser

Legacy Theses & Dissertations (2009 - 2024)

Domestic violence has been shown to increase the risk of bullying behavior among youth. Substance use and excess weight have also been linked to bullying behaviors. The purpose of this study was to determine what anti-bullying interventions have been implemented throughout the United States, and to identify the role of three risk factors (domestic violence, excessive weight or substance use) on bullying behaviors. For this study domestic violence will be defined as experiencing domestic violence or witnessing inter-parental domestic violence. A literature review (Study 1) was conducted to identify studies and summarize interventions aimed at reducing bullying behaviors among middle-school …

Factors Influencing Quality Of Life Of Persons Living With Human Immunodeficiency Virus Infection In Almaty, Kazakhstan, Bakhytkul Zhakipbayeva Zhakipbayeva

Legacy Theses & Dissertations (2009 - 2024)

Introduction: Health-related Quality of life (HRQoL) is recognized as a significant medical outcome measure for persons living with HIV (PLWH). Identification of potentially modifiable determinants of HRQoL could help target people in need of additional health care and social services in order to improve their HRQoL. The main objective of this study was to determine the factors with the strongest impact on HRQoL in PLWH.

Three Perspectives On Social Equity And Public Health Emergency Preparedness And Response Policy, Lucila M. Zamboni

Legacy Theses & Dissertations (2009 - 2024)

In the past 20 years, large-scale disasters have generated economic loss of $660 billion in the United States. Research has identified that low income individuals and economically vulnerable communities are at heightened risk and often experience disadvantages in access to public services during emergencies. Public administration literature has claimed that social equity should be included as a consideration together with economic and efficiency principles when formulating and implementing public policy. Yet there has been limited empirical research that follows this premise. The three studies that comprise this dissertation are guided by one overarching research question: which socioeconomic characteristics at the …

Pregnant Women With Congenital Heart Disease : Pregnancy Outcomes And Proximity To Care, Lauren Schlichting

Legacy Theses & Dissertations (2009 - 2024)

The number of adults living with congenital heart disease (CHD) now surpasses the number of children with the condition due to medical advances and the resulting increased survival rates in infants. However, much of the research focusing on proximity to specialty care for individuals with this complex condition has been with children. Pregnant women with these serious malformations are of particular concern, due to the stress of pregnancy on the circulatory system and the increase in risk for delivery complications. Few studies to date have described the healthcare utilization patterns at delivery and travel burden to specialty care for this …

Hepatitis C Status Awareness And Test Results Confirmation Among People Who Inject Drugs In Ukraine, Olena Iakunchykova

Legacy Theses & Dissertations (2009 - 2024)

Background. Hepatitis C virus (HCV) positivity is frequently found in people who inject drugs (PWID). The prevalence of HCV in this population in Ukraine is estimated at 71%. As treatment for HCV infection becomes more available, it is important to know what modifiable factors are related to testing, linkage to care and treatment.

Cumulative Risk And Chinese Adolescent Problematic Internet Use : The Mediating Role Of Self-Esteem, Xian Li

Legacy Theses & Dissertations (2009 - 2024)

A decade of research has documented the adverse effect of multiple ecological risks on adolescent problematic Internet use (PIU), yet existing research provides rather segmental explanations, and few studies offer a comprehensive and integrated account. A better theoretical and empirical understanding of the associations of multiple ecological risks and PIU, as well as the underlying mechanisms, could help inform intervention practices and policies to mitigate adolescent PIU.

Improving Hiv Outcomes In Pakistan : The Interaction Between Politics, Power And Implementation, Hina Khalid

Legacy Theses & Dissertations (2009 - 2024)

HIV contributes to the highest number of deaths from infectious diseases in low-income countries. In this three-paper dissertation, using the case of Pakistan, I focus on understanding how the exercise of power by actors at three different levels of the health system, individual, program and societal, influences policy implementation and shapes HIV program outcomes. The objective is to improve HIV service provision thereby achieving improved health policy outcomes. I adopt a mixed-methods approach and use quantitative (logit regression) and qualitative techniques (content analysis of newspapers and semi-structured interviews). One paper tests the role played by network operators in influencing condom …

Medical Student Burnout: A Social Cognitive Learning Perspective On Medical Student Mental Health And Wellness, Robert Lubin, Michael Hamlin

Touro University Worldwide Publications and Research

Medical students' mental health is a topic of great interest as it has implications not only for medical students but also for the patients of these future doctors. Medical students face many academic pressures and burnout is one possible consequence of these stressors with some studies suggesting that burnout affects up to 50% of medical students. Our own study of American students in a medical programme located outside of the U.S. showed that student perceptions of the medical learning environment were linked with burnout suggesting that reducing burnout requires a pedagogical approach that addresses academically related stress factors. This chapter …

Enhanced Potency Of Bivalent Small Molecule Gp41 Inhibitors, Vladimir Sofiyev, Hardeep Kaur, Beth A. Snyder, Priscilla A. Hogan, Roger G. Ptak, Peter Hwang, Miriam Gochin

Faculty Publications & Research of the TUC College of Osteopathic Medicine

Low molecular weight peptidomimetic inhibitors with hydrophobic pocket binding properties and moderate fusion inhibitory activity against HIV-1 gp41-mediated cell fusion were elaborated by increasing the available surface area for interacting with the heptad repeat-1 (HR1) coiled coil on gp41. Two types of modifications were tested: 1) increasing the overall hydrophobicity of the molecules with an extension that could interact in the HR1 groove, and 2) forming symmetrical dimers with two peptidomimetic motifs that could potentially interact simultaneously in two hydrophobic pockets on the HR1 trimer. The latter approach was more successful, yielding 40–60 times improved potency against HIV fusion over …

Multigenic Dna Vaccine Induces Protective Cross-Reactive T Cell Responses Against Heterologous Influenza Virus In Nonhuman Primates, Merika T. Koday, Jolie A. Leonard, Paul Munson, Adriana Forero, Michael Koday, Debra L. Bratt, Karen Duus

College of Osteopathic Medicine (TUN) Publications and Research

Recent avian and swine-origin influenza virus outbreaks illustrate the ongoing threat of influenza pandemics. We investigated immunogenicity and protective efficacy of a multi-antigen (MA) universal influenza DNA vaccine consisting of HA, M2, and NP antigens in cynomolgus macaques. Following challenge with a heterologous pandemic H1N1 strain, vaccinated animals exhibited significantly lower viral loads and more rapid viral clearance when compared to unvaccinated controls. The MA DNA vaccine induced robust serum and mucosal antibody responses but these high antibody titers were not broadly neutralizing. In contrast, the vaccine induced broadly-reactive NP specific T cell responses that cross-reacted with the challenge virus …

Benzylideneoxymorphone: A New Lead For Development Of Bifunctional Mu/Delta Opioid Receptor Ligands, Jason R. Healy, Padmavani Bezawada, Nicholas W. Griggs, Andrea L. Devereaux, Rae Reiko Matsumoto, John R. Traynor, Christopher W. Cunningham

Faculty Publications & Research of the TUC College of Pharmacy

Opioid analgesic tolerance remains a considerable drawback to chronic pain management. The finding that concomitant administration of delta opioid receptor (DOR) antagonists attenuates the development of tolerance to mu opioid receptor (MOR) agonists has led to interest in producing bifunctional MOR agonist/DOR antagonist ligands. Herein, we present 7-benzylideneoxymorphone (6, UMB 246) displaying MOR partial agonist/DOR antagonist activity, representing a new lead for designing bifunctional MOR/DOR ligands.

Evaluating Medical Students’ Proficiency With A Handheld Ophthalmoscope: A Pilot Study, Gregory Gilmour, James M. Mckivigan

College of Health & Human Services (TUN) Publications and Research

Introduction: Historically, testing medical students’ skills using a handheld ophthalmoscope has been difficult to do objectively. Many programs train students using plastic models of the eye which are a very limited fidelity simulator of a real human eye. This makes it difficult to be sure that actual proficiency is attained given the differences between the various models and actual patients. The purpose of this article is to introduce a method of testing where a medical student must match a patient with his/her fundus photo, ensuring objective evaluation as well as developing skills on real patients which are more likely to …

Complex Regional Pain Syndrome Type I Treated With Active Release Technique, Kathleen Hughes, James M. Mckivigan

College of Health & Human Services (TUN) Publications and Research

This report describes the examination, intervention, and outcome for a patient with CRPS type I treated with ART®. The patient was diagnosed with CRPS following a grade II ATFL sprain. For two months, treatment consisted of weekly 45-minute sessions including ART® in combination with self-massage, desensitization, joint mobilization, gait training, therapeutic exercise, and patient education. A brief reexamination was performed weekly. A clinically significant increase of 13 points on the LEFS was measured after eight weeks of treatment, as were improvements in quality of gait and gait distance. In addition, the patient experienced the return of ankle range of motion …

Efficacy Of Yoga Therapy In Treating Low Back Pain, James M. Mckivigan

College of Health & Human Services (TUN) Publications and Research

Background: Non-specific low back pain is a frequent condition that is often treated using non-pharmaceutical interventions such as exercise therapy. Yoga is one popular form of mind-body workout that can be applied to treat nonspecific low back pain.

Objective: To evaluate the impact yoga as a treatment therapy for chronic non-specific low back pain has on pain and functional ability in comparison to no exercise or the prescription of medication.

Search Methods: A review of existing studies that described randomized control trials that focused on the treatment of chronic low back pain with yoga and were published …

Nurses’ Knowledge Of Alcohol-Interactive Medications, Kyle Serafico

Honors Projects

Nearly 57% of adult Americans report drinking alcohol in the past month, and 41.5% of current drinkers take alcohol-interactive (AI) medications. Concurrent consumption of both substances can result in adverse interactions. Nurses are in a position to screen and appropriately teach patients. However, little is known about nurses’ knowledge of AI medications. The purpose of this study is to determine nurses’ knowledge of AI medications and factors that may affect knowledge level. The Jarvis Nursing Knowledge of Alcohol-Interactive Medications survey was developed and distributed to nurses employed by a large Midwestern health system. The final analyzed sample of nurses (n …

Adolescent Girls Empowerment Program (Agep): Evaluation—Round 4 Update, Karen Austrian, Paul C. Hewett, Erica Soler-Hampejsek, Jean Digitale

Poverty, Gender, and Youth

To assess the impact of the Adolescent Girls Empowerment Program (AGEP) on mediating and longer-term demographic, reproductive, and health outcomes, Population Council researchers designed and implemented a longitudinal, cluster randomized controlled trial across all program areas. A baseline survey was conducted in 2013 prior to program implementation and data have been collected annually. A third round of data collection in 2015 produced the midline findings, measuring the program effect immediately at the end of AGEP. Details of the midterm results were published in a full technical report, executive summary, and brief. The focus of this brief is to provide an …

Application Of The Multi-Facet Rasch Model To Validate Chief Residents Survey: A Two-Year Study, Kadriye O. Lewis, Ross Newman

Posters

This study compares the Chief Resident candidates' characteristics and leadership qualities within and across two years and further validates the Chief Resident peer selection instrument.

Prostate-Specific Antigen As A Risk Factor For Skeletal Metastasis In Native Ethnic African Men With Prostate Cancer: A Case-Control Study, Mahmood Qureshi, Khalid Makhdomi, William Stones

Imaging & Diagnostic Radiology, East Africa

Prostate cancer is the most common noncutaneous cancer in males. Men of African origin are at a significantly higher risk as reflected in the higher incidence and mortality rates in this racial group. Metastases incidence increases parallel to serum levels of prostate-specific antigen (PSA), contributing significantly to morbidity and mortality. Staging of the disease involves bone scans, which are sensitive in detecting skeletal metastases. Suggestions that these scans may be omitted in some situations in patients with low prostate specific antigen levels have drawn attention to the matter. In this case-control study, using radiology and pathology records, a registry of …

Scar Endometriosis: An Entity Not To Be Forgotten, Kulsoom Fatima, Samina Khanani

Department of Radiology

Scar endometriosis is an uncommon but well-described condition. It is caused by the dissemination of endometrial tissue in the wound at the time of surgery. The deposits can involve uterine scar, abdominal musculature or subcutaneous tissue, with the latter being the most common. It usually presents as a palpable mass at the scar site with or without cyclical pain. We report three cases of scar endometriosis which presented with cyclical pain and swelling at the abdominal wall scar following uterine surgery. The patients underwent imaging which revealed abnormal findings at the scar site suggesting scar endometriosis. In the presence of …

Advocating Corporate Policy Change On Women's Health And Family Planning: Lessons From The Environmental Movement, Matthew Mcfall, Carolyn Rodehau, David Wofford

Reproductive Health

This brief presents key lessons from the environmental movement on effective strategies for driving changes in corporate policies and practices and creating new mechanisms for holding businesses accountable for environmental impacts. Corporate policies and voluntary and “soft law” standards may be unfamiliar to many women’s health advocates, but they are likely to have increasing importance in the years to come. The global health community can learn from the experience of environmentalists on how to engage businesses on Corporate Social Responsibility (CSR) standards and corporate practices around women’s health. The brief offers six recommendations for moving forward.

Implementing Pharmacy-Based Travel Health Services: Insight And Guidance From Frontline Practitioners, Tania Gregorian, Albert Bach, Karl Hess, Keri Hurley, Edith Mirzaian, Jeff Goad

Pharmacy Faculty Articles and Research

PURPOSE In California, the passage of SB493 in July of 2013 was a milestone in advancing pharmacy practice. Among other things, the new legislation allows pharmacists to provide routine immunizations without a protocol and furnish medications for international travelers for conditions not requiring a diagnosis. When developing a pharmacist-run travel health service, consideration must be given to multiple important factors, including pharmacist training, physician partnership, logistics, from scheduling to documentation, and the resources necessary to provide a travel health service.5 This article sets out to provide guidance and insight to pharmacists seeking to implement a travel health service.

SUMMARY Travel …

The Effect Of Intrinsic And Extrinsic Motivations On Health Behavior In College Students: A Systematic Review, Kristen Melendez, Sharon Jalene

AANAPISI Poster Presentations

When measuring the weight of individuals to create healthy lifestyle plans with proper diet and exercise it is alarming how many people follow even the MINIMUM requirement to live a long healthy life. Research has proven that even people who are aware that they are overweight will likely only have a short-lived maintenance of healthy behaviors. Therefore, both intrinsic and extrinsic motivations were examined in order to better understand the difference between the population who maintains healthy lifestyles and those whose healthy habits are not sustained. Methods: A systematic review process was used to filter and screen for applicable studies …

Oncolog, Volume 62, Number 01, January 2017, Bryan Tutt, Joe Munch, Z Ahmed

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Neoadjuvant Immunotherapy for Melanoma: Trial investigates immune checkpoint blockade in patients with respectable stage III or oligometastatic stage IV disease.
• Radiation May Enhance Immunotherapy for Solid Tumors: Clinical Trials combine immune checkpoint inhibitors with radiation therapy against lung cancers, other solid tumors.
• INBRIEF: Nivolumab Plus Azacitidine Shows Promise in Relapsed Acute Myelogenous Leukemia/ Acute Myelogenous Leukemia, Myelodysplastic Syndrome Study Questions Standard Exclusion Criteria for Conventional Trials
• HOUSE CALL: Social Media Groups for Cancer Patients-Twitter chats, online groups for patients, caregivers
• USEFUL RESOURCES: Resources to Aid Referring Physicians

Actionable Patient Safety Solution (Apss) #3a: Medication Errors, Ron Jordan, Jerika Lam, Anne Lyren, Nathaniel Sims, Coco Yang

Pharmacy Faculty Articles and Research

This report presents a plan of action for introducing a program to reduce medication errors, which are a major cause of patient morbidity and mortality.

Prescribing Medications For Chronic Pain Management: The State Of Education In Florida Medical Schools And Residency Programs, Wyndham A. Bonnett, Katherine Perdomo, Suzanne C. Baker, Marshall B. Kapp

Florida Public Health Review

The purpose of this study was to assess the state of chronic, non-cancer pain management education in Florida medical schools and residency programs. Surveys were developed and distributed to Florida allopathic and osteopathic medical schools. One survey was specific to students and residents and one to faculty. Confidence in their general education, as well as in treating patients with chronic, non-cancer pain, was measured. A majority of medical students and residents (59.5%), in addition to a majority of faculty (58.1%), agreed or strongly agree that more clinical time needs to be dedicated to chronic, non-cancer pain management education. Students, residents, …

Documenting Support For Ongoing And Improved Efforts In Sexuality Education, Elissa M. Barr, Michele J. Moore, Kristina Wilson, Tiffany L. Parisi, Heather M. Mccann

Florida Public Health Review

As debate regarding sexuality education continues, STD, HIV, and teen pregnancy rates remain high. Garnering support is critical to ensure quality programs addressing these public health concerns. As part of a funded project to reduce adolescent sexual health issues in a large Florida county, this study assessed voter support for specific sexuality education topics. A survey was developed after reviewing existing instruments. The university’s Public Opinion Research Laboratory used random-digit-dialing to administer the survey (N=311). Most participants supported topics taught in middle school: dealing with pressure to have sex (85%), talking to parents about sex (90%), human anatomy/reproduction (91%), HIV/STDs …