Medicine and Health Sciences Commons^™

Identifying The Relationship Between Benzene Exposure And The Development Of Acute Myeloid Leukemia, Jacqueline G. Tally

Senior Honors Projects

My interest in epigenetic carcinogenesis-related research stems from both academic and personal experiences. I have come to recognize the significance of environmental chemical exposures in the development of cancer through my studies in nursing, and nutrition and food science. I am particularly interested in the epigenetics of acute myeloid leukemia (AML) because I am an AML survivor.

AML is a rare and highly malignant cancer. It is estimated 13,780 new cases of AML will be identified in theUnited Statesthis year with a 74% mortality rate (calculated 10,200 deaths/13,780 new cases). AML develops from alterations in the survival and proliferation of …

An Investigation Of The Role Of Gabab Ligands On Cued And Contextual Fear Conditioning, Chelcie F. Heaney

UNLV Theses, Dissertations, Professional Papers, and Capstones

GABA is the primary inhibitory neurotransmitter in the brain and mediates several processes, including learning and memory. Activating or inhibiting GABA receptors allows for the examination of the effects of altered GABAergic signaling on these processes. The two main receptors, GABAA and GABAB, each have a different mechanism of action when activated, thus they may contribute differentially to learning and memory. The metabotropic GABAB receptor responds with the activation of several intracellular signaling cascades, which provide long-lasting inhibitory effects that primarily mediate network function. Conversely, the GABAA receptor is an ion channel that contributes more immediate inhibitory effects through the …

Cultural Competence In The Baccalaureate Degree Nursing Curriculum, Angela Elizabeth Silvestri

UNLV Theses, Dissertations, Professional Papers, and Capstones

Health care providers are members of a helping profession and need to provide quality care to all members of society. As a result of current and projected demographic changes within the United States (U.S.), health care professionals are faced with the challenges of providing culturally competent care and fulfilling the role as the "helping profession." In the past 10 years, minority populations have increased in the U.S. For example, the African American population experienced an approximate 12.3% increase, and the Hispanic population increased by 43%. Just as it is necessary for health care professionals to respond to the increase in …

Perceptions Of Barriers That Inhibit African American Women And Adolescent Girls From Participation In Physical Activity, Sonya Daniels Walker

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study examined the barriers to leisure time physical activity for African American women and their adolescent daughters. Six mother-daughter dyads were interviewed who have access to physical activity opportunity. Three of the dyads participated in a follow-up focus group. A qualitative research design that utilized a grounded theory approach identified two themes for the women and two themes for the girls. Themes for the women include influence of culture and low physical activity IQ. Sub-themes of influence of culture are (a) hair and (b) body image. Sub-themes of low physical activity IQ are (a) mommy guilt, (b) perception of …

Immediate Effects Of High Intensity Training In Children With Cerebral Palsy Gmfcs Levels I-Iii: A Pilot Study, Andrea Blahovec, Andrea Kuiken, Jillian Mears, Heather Riggins

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: Cerebral Palsy is one of the most common causes of motor disability in the U.S., but there is still a lack of consensus for best intervention strategies to improve function and gait efficiency.

Objective: Determine if ambulatory children with CP, exposed to a brief, high intensity training session, will: 1) experience changes in temporal-spatial gait characteristics 2) demonstrate increased gait speed and 3) demonstrate improved gait kinematics.

Design: Five participants walked at preferred and fast speeds over an instrumented walkway followed by a 15-minute intervention. After a short rest, post-intervention walking was completed.

Results: Ten dependent variables were extracted …

The Effect Of The Environment On Sport Concussion Assessment Tool 2 (Scat2) Scores, Deanna Smith

Undergraduate Theses and Capstone Projects

With the incidence of concussion in sport on the rise, it is crucial that the concussion assessment tools utilized by health care professionals be accurately administered in the appropriate setting. It may be important to consider the environment of test administration between baseline and post-injury assessment to allow appropriate return to play decisions. At present, there is limited research on the effect of testing environment on Sport Concussion Assessment Tool 2 (SCAT2) baseline scores. Our objective for the study was to investigate if testing environment affects SCAT2 scores in healthy male collegiate club lacrosse players and healthy female club soccer …

Adult Ecmo And Gastrointestinal Bleeding From Small Bowel Arteriovenous Malformations: A Novel Treatment Using Spiral Enteroscopy., Konrad Sarosiek, Hitoshi Hirose, Harrison T Pitcher, Nicholas C. Cavarocchi

Department of Surgery Faculty Papers

Hemorrhagic complications on extracorporeal membrane oxygenation (ECMO) are common because of the need for anticoagulation to maintain the oxygenator and circuitry. Gastrointestinal bleeding (GIB) is reported to occur in 3-6% of ECMO patients, ¹ requiring frequent transfusions as well as multiple diagnostic and therapeutic interventions. Multiple transfusions can result in volume overload, coagulopathies and infections leading to significant morbidity and mortality. We present the first published case of GIB from an arteriovenous malformation (AVM) treated with a novel therapy termed spiral enteroscopy while the patient remained on venoarterial (VA) ECMO.

Effects Of Temperature On Emergence And Seasonality Of West Nile Virus In California, David M. Hartley, Christopher M. Barker, Arnaud Le Menach, Tianchan Niu, Holly Gaff, William K. Reisen

Biological Sciences Faculty Publications

Temperature has played a critical role in the spatiotemporal dynamics of West Nile virus transmission throughout California from its introduction in 2003 through establishment by 2009. We compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (BT), and the fundamental reproductive ratio (R₀) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral amplification. Maps of BT and R₀ were created at 20-km scale and compared throughout California to seroconversions in sentinel chicken flocks at half-month intervals. Overall, estimates of BT and …

Short-Term Estrogen-Depletion-Related Changes In Anatomic Variation Of Time-Dependent Material Properties, And Evidence Of Secondary Remodeling Of Ovine Compact Bone, Ryan Allen, Kathleen De Guzman

Biomedical Engineering

Recognized as the most common type of bone disease in humans, osteoporosis poses a major health threat to roughly 28 million Americans [1]. In women, the leading cause of osteoporosis is known to be a drop in estrogen during the time of menopause. Thus, it becomes essential to acquire a better understanding of postmenopausal osteoporosis, as many individuals desire a longer lifetime and an improved quality of life for the elderly. To further current knowledge of postmenopausal osteoporosis and help develop methods of overcoming it, it is important to find an appropriate animal model.

In this study, pretreated ovine compact …

Problems And Issues In Implementing Innovative Curriculum In The Developing Countries: The Pakistani Experience, Syeda Kauser Ali, Lubna A. Baig

Department for Educational Development

Background: The Government of Pakistan identified 4 medical Colleges for introduction of COME, one from each province. Curriculum was prepared by the faculty of these colleges and launched in 2001 and despite concerted efforts could not be implemented. The purpose of this research was to identify the reasons for delay in implementation of the COME curriculum and to assess the understanding of the stakeholders about COME.

Methods: Mixed methods study design was used for data collection. In-depth interviews, mail-in survey questionnaire, and focus group discussions were held with the representatives of federal and provincial governments, Principals of medical colleges, faculty …

Muscular Activity Characteristics Associated With Preparation For Gait Transition, Li Li, Lorna L. Ogden

Health Sciences & Kinesiology: Faculty Publications

Purpose: The purpose of this study was to investigate lower extremity neuromuscular activity patterns during gait transitions with continuously changing locomotion speeds.

Methods: Muscular activities related to gait transitions (walk to run and run to walk) induced by changing treadmill speed were compared to muscular activities during walk and run at constant speeds. All transition and constant speed conditions were conducted in similar speed range. Surface electromyographic activities of gluteus maximus (GM), rectus femoris (RF), vastus lateralis (VL), biceps femoris long head (BFL), tibialis anterior (TA), gastrocnemius (GA), and soleus (SL) were collected and analyzed. The influences of speed and …

People Can Live Longer By Having More Physical Activity, Li Li

Health Sciences & Kinesiology: Faculty Publications

We all know being physically active is good for you. But do we know how good? People can live up to 3 years longer, even with as little as 15 min of physical activity a day, according to last October's report by Wen and his colleagues¹at the China Medical University in Taiwan, China.

Many researchers in the field of sport and health sciences know being physically active can bring many benefits to one's life. But this message has sometimes been disseminated using a negative tone. So much so, Bortz² of California, USA, has coined the word “inactivity” …

Characterization Of The Vasotocin Receptor Subtype 4 (Vt4r) In The Brain And Pituitary Gland Of The Chicken, Gallus Gallus, Rajamani Selvam

Graduate Theses and Dissertations

The present study investigated the distribution of the vasotocin subtype four receptor (VT4R) in brain and pituitary gland of the chicken, Gallus gallus. The anterior pituitary cell types associated with the VT4R were also determined. Two polyclonal antibodies were raised in rabbit against a cocktail of peptides, 15 amino acids from the amino terminal region and 17 amino acids from the carboxy terminal region of VT4R receptor. The antibody was validated utilizing the Western blot and immunocytochemistry. A single band at 47KDa utilizing membrane protein extracts of chicken brain and pituitary tissues was shown for the VT4R antibody. A peptide …

Exploring Hope And Quality Of Life: A Proposal For A Group Art Therapy Hope Intervention For Individuals Diagnosed With Lupus, Paige Scheinberg

EVMS School of Health Professions Theses & Dissertations

As a result of the importance of hope and quality of life in disease management for individuals who have been diagnosed with lupus, there is support in the literature for the need for an effective intervention that targets these constructs with this population. The efficacy of art therapy in meeting the physical, mental, and emotional needs of diverse populations is also supported in existing research, making this an ideal form of treatment for lupus patients. In an effort to fill a gap in the literature on the relationship(s) between lupus, hope, and art therapy, this study was created. The original …

A Comparison Of Kinetic Family Drawings By Children With Autism Spectrum Disorder And Typically Developing Siblings, Rachel Daniels

EVMS School of Health Professions Theses & Dissertations

The purpose of this study was to identify the effects of Autism Spectrum Disorder (ASD) on the diagnosed child’s perception of their family. Specifically, the study compared the Kinetic Family Drawings (Burns & Kaufman, 1970) created by children diagnosed with Autism and those created by typically developing children.

Eight participants between the ages of 6 and 12 were recruited, and split into two groups. One group consisted of four children (three boys and one girl) with a mean age of 6.75 and an Autism Spectrum Disorder Diagnosis. The second group consisted of four typically developing children (three girls and one …

What Is The Effect Of Mandala Drawing Versus Art Card Sorting On Mood, Stress, And Anxiety In Individuals With Mood And Anxiety Disorders?, Sara K.M. Young

EVMS School of Health Professions Theses & Dissertations

The effect of mandala drawing versus art card sorting on mood, stress, and anxiety on a clinical population of adults with a history or diagnosis of DSM-­‐IV-­‐TR mood and/or anxiety disorders is investigated through a randomized study utilizing experiment and control groups, and a single subject case study. Standardized measurements used to collect data were the profile of mood states, the state-­‐trait anxiety inventory, and the Beck depression inventory-­‐II. Statistical significance could not be tested due to a lack of control subjects. Mean and standard deviation are reported and show a decrease in the mean post experiment. The single subject …

Burnout, Vicarious Traumatization, And Compassion Fatigue Within The Field Of Art Therapy, Megan Parrish

EVMS School of Health Professions Theses & Dissertations

Burnout, compassion fatigue, and vicarious traumatization are negative experiences that can pose problems for many health professionals, especially mental health professionals. This study is a preliminary study aimed at identifying the prevalence of these experiences within the field of art therapy. A mixed methods research design consisting of pre-existing measurements and qualitative questions were implemented into an online survey and dispersed through various online media. There were 88 participants who completed the survey. Responses were analyzed with results indicating that there was a presence of burnout, compassion fatigue, and vicarious traumatization within the field. Another aspect of the study was …

A Comparative Analysis Of Stress And Anxiety Reduction Between Working With Clay And Mandala Design Coloring, Sara Julsrud

EVMS School of Health Professions Theses & Dissertations

One aim of this study was to help scientifically quantify many art therapists’ belief that artmaking is intrinsically healing. This study explored the effects of mindful art therapy processes (guided clay work meditation and mandala coloring) on stress and anxiety through measurements of blood pressure, heart rate, respiratory rate, and the State-Trait Anxiety Inventory (STAI). Data were collected from 20 undergraduate students from Virginia Wesleyan College and Old Dominion University, both of Norfolk, VA. Ages of subjects ranged from 18 to 40 years old. Through use of repeated measures analysis, the posttest measurements from each subject were compared to their …

Emergency Medical Technicians’ Experience With Visual Journaling: A Qualitative Study, Pamela Gandolfi

EVMS School of Health Professions Theses & Dissertations

The purpose of this study was to understand the experience of EMTs who incorporate the process of visual journaling each week in response to their professional responsibilities. In particular, this study aimed to understand EMTs’ perceptions of the usefulness of visual journaling and to determine possible themes from visual and written journal content.

Six participants, five male and one female, who were certified EMT-Basic (EMT-B), EMT-Intermediate (EMT-I) and Paramedics (EMT-P) volunteered to be part of this study. In addition to being an EMT, they were all also certified firefighters. All participants were aged 18 to 70 years and had met …

A Study Of Art Therapy-Based Approaches To Communication Between Physicians And Pediatric Patients, Carrie Carowan

EVMS School of Health Professions Theses & Dissertations

Miscommunication between physicians and child patients about perceived pain results in problems with diagnosis and treatment of childhood illness. This study used an art therapy-based approach to explore physician perceptions and understanding of child patients’ pain as compared to the pediatric patients’ perceptions of their own pain. Body Outline Forms (BOFs) and Magnified Pain Drawings (MPDs) (Barton, 1995) were completed by participants, and compared using a qualitative content analysis. Visual results reflected a difference in perception of pain by the physician and child participants in areas of color, size, shape, location, and movement. Verbal results collected from the physician participant …

Art Therapy And Quality Of Life In Older Adults: A Case Study, Ashton Sullivan

EVMS School of Health Professions Theses & Dissertations

This case report describes my exploration of quality of life by implementing art therapy techniques for life review with an elderly individual. The participant was a 72 year old Caucasian female who, at the time of this investigation, resided in a long term care facility. Together, the participant and I created an altered book incorporating phototherapy techniques in order to enhance the life review process. After seven sessions of art making, the participant answered questions in a semi-structured interview in which I asked about her experience in art therapy and about her quality of life. The results of the interview …

Examining Attachment Styles In Adult Adoptees Using The Bird’S Nest Drawing, Kim Clemens

EVMS School of Health Professions Theses & Dissertations

The purpose of this study is to examine adult attachment styles seen in the Bird’s Nest Drawings of adopted adults, compared to those seen in non-adopted adults. A sample of 17 participants (16 non-adopted adults and 1 adopted adult) in the age range of 21-57 completed a Bird’s Nest Drawing (BND), Bird’s Nest Drawing Story, Adult Attachment Scale Questionnaire, and a demographic questionnaire.

The BND was devised by Donna Kaiser to assess secure and insecure attachment as seen through graphic indicators in a projective drawing test. Kaiser’s February 2012 updated BND checklist is comprised of 14 hypothesized graphic indicator items, …

A Proposed Art Therapy Group For Survivors Of Suicide Based Upon The Results Of A Survivor Of Suicide’S Self-Study, Crystal Menicola

EVMS School of Health Professions Theses & Dissertations

A survivor of suicide’s self-exploration process was explored to investigate the efficacy and applicability of specific therapeutic art and writing tasks proposed in the original methodology for the study of an art therapy group with survivors of suicide. Based on personal reflections throughout the self-exploration process, the researcher improved the original study design by modifying the sequence of tasks and adding supplemental art and writing exercises to sessions in consideration of evocative material that had the potential to elicit a severe trauma response due to recalling traumatic memories. Two standardized measures, the PTSD Checklist-Civilian Version, and the Trauma Symptom Checklist-40, …

A Phenomenological Observation Of The Reductive Printmaking Experience: Implications For Art Therapy, Nicholas Alexander

EVMS School of Health Professions Theses & Dissertations

This qualitative study examined the phenomenological experience of four students in higher education relating to the involvement in a single reductive relief printmaking session. The indirect process of reductive relief printmaking is set apart from other methods due to the multiple steps and the use of various tools during the experience. It offers a reflective distance from the process, which allows the participant time to consider the meaning of an experience as it occurs. The production of multiple images during the process likewise lessens a participant’s resistance. The printed images are composed of layers; a metaphor for life’s process. Prior …

Predictors Of New Graduate Nurses’ Organizational Commitment During A Nurse Residency Program, Marilyn Meyer Bratt, Holly M. Felzer

College of Nursing Faculty Research and Publications

Retaining newly graduated nurses is critical for organizations because of the significant cost of turnover. Since commitment to an organization is associated with decreased turnover intent, understanding factors that influence new graduates’ organizational commitment is important. In a sample of nurse residency program participants, predictors of organizational commitment over time were explored. Perceptions of the work environment, particularly job satisfaction and job stress, were found to be most influential.

Nurse residency programs provide extended opportunities to model professional role behaviors for new nurses, enhance knowledge development and clinical application, and promote successful integration to the work environment (Bratt, 2009). Despite …

Exploring Associations Between Group Yoga Participation Over Time, Psycho-Social Variables And Exercise Adherence, Stephanie L. Bryan

Seton Hall University Dissertations and Theses (ETDs)

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Off-Label Prescribing: Pediatrician Beliefs And Experience, Elizabeth G. Evola

Seton Hall University Dissertations and Theses (ETDs)

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Illness Perceptions Of Hemodialysis Patients With Type 2 Diabetes Mellitus And Their Association With Empowerment, Jaime L. Pula

Seton Hall University Dissertations and Theses (ETDs)

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Infiltrating Ductal Carcinoma Of Breast Presenting As Areolar Dermal Lesion, Gulnaz Shafqat, Shaista Khan, Khurram Minhas, Shaista Afzal

Department of Radiology

Infiltrating ductal carcinoma is the most common form of invasive breast cancer. It accounts for 80% of all types of breast cancer. We report an unusual presentation of histologically proven case of infiltrating ductal carcinoma of breast presented clinically as a small palpable areolar dermal lesion. Well defined hypoechoic cystic lesion in areolar dermis was present on ultrasound with a negative mammogram.

What Is The Role Of Free Radical Scavengers In Acute Stroke?, Muhammad Faisal Wadiwala, Ambreen Sonawalla, Ayeesha Kamran Kamal

Section of Neurology

No abstract provided.