Medicine and Health Sciences Commons^™

A Collaborative Care Summit: A Regional Model Of Interprofessional Education, Karen Arscott, Diane Haleem, Edward Foote, Maria Olenick

JCIPE 2012

Purpose: To describe an interprofessional summit

Background: Northeastern/North CentralPennsylvania is home to several excellent healthcare education programs. Unfortunately these programs are somewhat smaller and isolated with most universities/colleges housing just a few disciplines. Interprofessional education requires collaboration across institutions, professions, and county lines. The Northeast/central Interprofessional Education Coalition, comprised of a group of educators from 12 colleges and universities, was created in 2008 with a mission to promote IPE in our region.

Description of Intervention: An Interprofessional Care Summit was held on March 30, 2011 at five different sites inScranton,Wilkes-Barre andWilliamsport. The collaborative team designed a case …

Ranking Library Tasks For Redesigning A Medical Academic Health Center And University Mobile Web Site, Daniel G. Kipnis, Msi, Gary Kaplan, Mslis, Ann Koopman, Am, Brian Kysela, Joseph Zavorski

Academic Commons and Scott Memorial Library Staff Papers and Presentations

Objectives:

(1) To determine what library-related tasks users most want to be able to perform on their mobile devices (smartphones, iPads,etc.), using a modified Likert scale, freetext and multiple choice questions to rank the most common tasks.

(2) To redesign our existing Library mobile site.

Validation Of 3'-Deoxy-3'-[18f]-Fluorothymidine Positron Emission Tomography For Image-Guidance In Biologically Adaptive Radiotherapy, Marian Axente

Theses and Dissertations

Accelerated tumor cell repopulation during radiation therapy is one of the leading causes for low survival rates of head-and-neck cancer patients. The therapeutic effectiveness of radiotherapy could be improved by selectively targeting proliferating tumor subvolumes with higher doses of radiation. Positron emission tomography (PET) imaging with 3´-deoxy-3´-[18F]-fluorothymidine (FLT) has shown great potential as a non-invasive approach to characterizing the proliferation status of tumors. This thesis focuses on histopathological validation of FLT PET imaging specifically for image-guidance applications in biologically adaptive radiotherapy. The lack of experimental data supporting the use of FLT PET imaging for radiotherapy guidance is addressed by developing …

The Pharmacist Supply In The United States, 1994-2009: A Population Ecology Perspective, Kevin S.J. Lett

Theses and Dissertations

The U.S. healthcare system is a complex segment of our society that is constantly evolving with changes to various areas such as education, financing, safety, and health. There continues to be a critical examination of how healthcare professionals are trained and utilized as healthcare demands increase. One category of healthcare professionals that has evolved over time to address societal needs is pharmacists. Pharmacists have kept their traditional function of dispensing medications while expanding into multiple areas of expertise and training from patient counseling and drug therapy, to being part of multidisciplinary teams treating acute care patients. According to the National …

The Closure Of New Orleans' Charity Hospital After Hurricane Katrina: A Case Of Disaster Capitalism, Kenneth Brad Ott

LSU New Orleans Theses and Dissertations

Abstract

Amidst the worst disaster to impact a major U.S. city in one hundred years, New Orleans’ main trauma and safety net medical center, the Reverend Avery C. Alexander Charity Hospital, was permanently closed. Charity’s administrative operator, Louisiana State University (LSU), ordered an end to its attempted reopening by its workers and U.S. military personnel in the weeks following the August 29, 2005 storm. Drawing upon rigorous review of literature and an exhaustive analysis of primary and secondary data, this case study found that Charity Hospital was closed as a result of disaster capitalism. LSU, backed by Louisiana state officials, …

Effect Of Age And Vaccination On Extent And Spread Of Chlamydia Pneumoniae Infection In C57bl/6 Mice, Taylor Eddens, Sarah Beaudoin, Amanda Steinberger, Christopher Scott Little, Dawn Shell, Benjamin Wizel, Brian J. Balin Phd, Kerin L. Fresa-Dillon

PCOM Scholarly Works

BACKGROUND: Chlamydia pneumoniae is an obligate intracellular respiratory pathogen for humans. Infection by C. pneumoniae may be linked etiologically to extra-respiratory diseases of aging, especially atherosclerosis. We have previously shown that age promotes C. pneumoniae respiratory infection and extra-respiratory spread in BALB/c mice.

FINDINGS: Aged C57BL/6 mice had a greater propensity to develop chronic and/or progressive respiratory infections following experimental intranasal infection by Chlamydia pneumoniae when compared to young counterparts. A heptavalent CTL epitope minigene (CpnCTL7) vaccine conferred equal protection in the lungs of both aged and young mice. This vaccine was partially effective in protecting against C. …

Intelligibility And The Sinewave Speech Carrier Phrase Effect, Danielle R. Werle

Honors Theses

Several studies have examined the perception of sinewave speech. Early work showed that listeners could transcribe sinewave sentences. Recent work on sinewave vowels found that listeners could recognize sinewave speech at the phonetic level with moderate (about 50-55%) accuracy. Sinewave vowel intelligibility scores improve significantly when preceded by a sinewave carrier phrase, an effect that disappears when the carrier phrase is removed. The present study was designed to examine this carrier phrase enhancement effect and analyze whether listeners require the carrier phrase to be intelligible to produce increased intelligibility scores. Sinusoidal carrier phrases and /hVd/ syllables were generated from recordings …

Louisiana State University Health Sciences Center - 2012 - 138th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 138th Commencement of LSU Health Sciences Center - New Orleans held May 17, 2012.

A Compassionate Allowance, And Faster Social Security Benefits, For The Juvenile Huntington's Disease Community: A Key Step For Advocacy, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Integrin Activation By A Cold Atmospheric Plasma Jet, Olga Volotskova, Mary Ann Stepp, Michael Keidar

Anatomy and Regenerative Biology Faculty Publications

Current breakthrough research on cold atmospheric plasma (CAP) demonstrates that CAP has great potential in various areas, including medicine and biology, thus providing a new tool for living tissue treatment. In this paper, we explore potential mechanisms by which CAP alters cell migration and influences cell adhesion. We focus on the study of CAP interaction with fibroblasts and corneal epithelial cells. The data show that fibroblasts and corneal epithelial cells have different thresholds (treatment times) required to achieve maximum inhibition of cell migration. Both cell types reduced their migration rates by ~30–40% after CAP compared to control cells. Also, the …

A Successful Model Of Road Traffic Injury Surveillance In A Developing Country: Process And Lessons Learnt, Junaid Abdul Razzak, Muhammad Shahzad Shamim, Amber Mehmood, Syed Ameer Hussain, Mir Shabbar Ali, Rashid Jooma

Department of Emergency Medicine

Background: Road Traffic Injuries (RTIs) are one of the leading causes of death and disability worldwide with 90% of global mortality concentrated in the low and middle income countries. RTI surveillance is recommended to define the burden, identify high risk groups, plan intervention and monitor their impact. Despite its stated importance in the literature, very few examples of sustained surveillance systems are reported from low income countries. This paper shares the experience of setting up an urban RTI surveillance program in the emergency departments of five major hospitals in Karachi, Pakistan.
Method: We describe the process of establishing a surveillance …

Beta2-Adrenoceptor Agonists For Dysmenorrhoea, Zbys Fedorowicz, Mona Nasser, Vanitha A. Jagannath, Jessica H. Beaman, Kiran Ejaz, Esther J. Van Zuuren

Department of Emergency Medicine

Background:Dysmenorrhoea is a common gynaecological complaint that can affect as many as 50% of premenopausal women, 10% of whom suffer severely enough to be rendered incapacitated for one to three days during each menstrual cycle. Primary dysmenorrhoea is where women suffer from menstrual pain but lack any pathology in their pelvic anatomy. Beta2-adrenoceptor agonists have been used in the treatment of women with primary dysmenorrhoea but their effects are unclear.
Objectives:To determine the effectiveness and safety of beta2-adrenoceptor agonists in the treatment of primary dysmenorrhoea. Search methods: We searched the Cochrane Menstrual Disorders and Subfertility Group Specialised Register, …

Egr-1 Induces Darpp-32 Expression In Striatal Medium Spiny Neurons Via A Conserved Intragenic Element., Serene Keilani, Samira Chandwani, Georgia Dolios, Alexey Bogush, Heike Beck, Antonis K Hatzopoulos, Gadiparthi N Rao, Elizabeth A Thomas, Rong Wang, Michelle E Ehrlich

Farber Institute for Neuroscience Faculty Papers

DARPP-32 (dopamine and adenosine 3', 5'-cyclic monophosphate cAMP-regulated phosphoprotein, 32 kDa) is a striatal-enriched protein that mediates signaling by dopamine and other first messengers in the medium spiny neurons. The transcriptional mechanisms that regulate striatal DARPP-32 expression remain enigmatic and are a subject of much interest in the efforts to induce a striatal phenotype in stem cells. We report the identification and characterization of a conserved region, also known as H10, in intron IV of the gene that codes for DARPP-32 (Ppp1r1b). This DNA sequence forms multiunit complexes with nuclear proteins from adult and embryonic striata of mice and rats. …

Scavenger Receptor Cd36 Expression Contributes To Adipose Tissue Inflammation And Cell Death In Diet-Induced Obesity, Lei Cai, Zhen Wang, Ailing Ji, Jason M. Meyer, Deneys R. Van Der Westhuyzen

Internal Medicine Faculty Publications

OBJECTIVE: The enlarged adipose tissue in obesity is characterized by inflammation, including the recruitment and infiltration of macrophages and lymphocytes. The objective of this study was to investigate the role of the scavenger receptor CD36 in high fat diet-induced obesity and adipose tissue inflammation and cell death.

EXPERIMENTAL APPROACH: Obesity and adipose tissue inflammation was compared in CD36 deficient (CD36 KO) mice and wild type (WT) mice fed a high fat diet (60% kcal fat) for 16 weeks and the inflammatory response was studied in primary adipocytes and macrophages isolated from CD36 KO and WT mice.

RESULTS: Compared to WT …

A Framework Convention On Global Health: Health For All, Justice For All, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

Health inequalities represent perhaps the most consequential global health challenge and yet they persist despite increased funding and innovative programs. The United Nations is revising the Millennium Development Goals (MDGs) that will shape the world for many years to come. What would a transformative post-MDG framework for global health justice look like? A global coalition of civil society and academics—the Joint Action and Learning Initiative on National and Global Responsibilities for Health (JALI)—has formed an international campaign to advocate for a Framework Convention on Global Health (FCGH). Recently endorsed by the UN Secretary-General, the FCGH would reimagine global governance for …

A Spoonful Of Sugar, Natali Bode

Tredway Library Prize for First-Year Research

No abstract provided.

Développement D'Une Méthode De Mesure De La Pénétration Des Nanoparticules À Travers Les Matériaux De Gants De Protection Dans Des Conditions Simulant L'Utilisation En Milieu De Travail, Patricia Dolez, Ludwig Vinches, Gérald Perron, Toan Vu-Khanh, Philippe Plamondon, Gilles L'Espérance, Kevin Wilkinson, Yves Cloutier, Chantal Dion, Ginette Truchon

Rapports de recherche scientifique

En raison de la croissance exponentielle des applications industrielles des nanotechnologies et de l'augmentation associée des risques d'exposition professionnelle aux nanomatériaux, le principe de précaution a été recommandé. Afin de le mettre en œuvre et même s'ils ne doivent être considérés qu'en dernier recours dans la stratégie de maîtrise des risques, des équipements de protection individuelle contre les nanoparticules doivent être disponibles. Dans le but de combler le manque actuel en termes d'outils et de connaissances dans ce domaine, une méthode de mesure de la pénétration des nanoparticules à travers les matériaux de gants de protection dans des conditions simulant …

Vascular Anatomy Of The Tibiofibular Syndesmosis, Kathleen E. Mckeon, Rick W. Wright, Jeffrey E. Johnson, Jeremy J. Mccormick, Sandra E. Klein

Open Access Publications

No abstract provided.

2012 May 15 - Medical Student Education Committee Minutes Called Meeting, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

The Science Of Public Health Practice: Using Pbrns For Delivery System Research In Public Health Settings, Glen P. Mays

Health Management and Policy Presentations

PBRN research tests strategies for improving the delivery of services that promote health and prevent disease and injury on a population-wide basis.

Bis-Quaternary Ammonium Salts And Methods For Modulating Neuronal Nicotinic Acetylcholine Receptors, Peter Crooks, Linda P. Dwoskin, Guangrong Zheng, Sangeetha Sumithran, Marharyta Pivavarchyk

Pharmaceutical Sciences Faculty Patents

Provided are bis-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.

Qualitative Evaluation Of Project P.A.T.H.S.: An Integration Of Findings Based On Program Participants, Daniel T. L. Shek, Rachel C. F. Sun

Pediatrics Faculty Publications

An integration of the qualitative evaluation findings collected in different cohorts of students who participated in Project P.A.T.H.S. (Positive Adolescent Training through Holistic Social Programmes) (n = 252 students in 29 focus groups) was carried out. With specific focus on how the informants described the program, results showed that the descriptions were mainly positive in nature, suggesting that the program was well received by the program participants. When the informants were invited to name three metaphors that could stand for the program, positive metaphors were commonly used. Beneficial effects of the program in different psychosocial domains were also voiced by …

Golf: An Alternative Form Of Physical Activity For An Aging Population, Lisa Richardson

Honors Theses

It has been found that breaking an exercise into multiple ten minute bouts can provide the same results as a lump bout of the same time (American College of Sports Medicine, 2010). Though little research has been done on its effectiveness as a modality of physical activity, golf, due to the considerable amounts of walking involved and the social and leisure nature of the game, could be used as an option of physical activity for older adults. In this literature review, the primary goal is to investigate the literature regarding how much energy an older adult could predictably expend while …

Emergency Nurses' Perception Of Department Design As An Obstacle To Providing End-Of-Life Care, Renea L. Beckstrand, Ryan J. Rasmussen, Karlen E. (Beth) Luthy, Sondra Heaston

Faculty Publications

Introduction: Of the 119.2 million visits to the emergency department in 2006, it was estimated that about 249,000 visits resulted in the patient dying or being pronounced dead on arrival. In 2 national studies of emergency nurses' perceptions of end-of-life (EOL) care, ED design was identified as a large and frequent obstacle to providing EOL care. The purpose of this study was to determine the impact of ED design on EOL care as perceived by emergency nurses and to determine how much input emergency nurses have on the design of their emergency department.

Methods: A 25-item questionnaire regarding ED …

Polyamidoamine Dendrimer Nanoparticle Cytotoxicity, Oxidative Stress, Caspase Activation And Infammatory Response: Experimental Observation And Numerical Simulation, Sourav Prasanna Mukherjee, Hugh Byrne

Articles

Mechanisms underlying the in vitro cytotoxicity of Polyamidoamine nano-dendrimers in human keratinocytes are explored. Previous studies demonstrated a systematic, dendrimer-generation-dependent cytotoxicity, oxidative stress, and genotoxicity. The emerging picture is of dendrimer endocytosis, endosomal rupture and subsequent mitochondrial attack and cell death. To understand the underlying mechanisms, the evolution of reactive oxygen species, intracellular glutathione, caspase activation, mitochondrial membrane potential decay, and inflammatory responses have been examined. Early-stage responses are associated with endosomal encapsulation, later-stage with mitochondrial attack. In all cases, the magnitude and evolution of responses depend on dendrimer generation and dose. The early-stage response is modelled using a rate …

Posttraumatic Stress And Myocardial Infarction Risk Perceptions In Hospitalized Acute Coronary Syndrome Patients, Donald Edmondson, Jonathan A. Shaffer, Ellen-Ge Denton, Daichi Shimbo, Lynn Clemow

Publications and Research

Posttraumatic stress disorder (PTSD) is related to acute coronary syndrome (ACS; i.e., myocardial infarction or unstable angina) recurrence and poor post-ACS adherence to medical advice. Since risk perceptions are a primary motivator of adherence behaviors, we assessed the relationship of probable PTSD to ACS risk perceptions in hospitalized ACS patients (n = 420). Participants completed a brief PTSD screen 3-7 days post-ACS, and rated their 1-year ACS recurrence risk relative to other men or women their age. Most participants exhibited optimistic bias (mean recurrence risk estimate between "average" and "below average"). Further, participants who screened positive for current PTSD (n …

Concurrent Intracranial And Spinal Arteriovenous Malformations: Report Of Two Pediatric Cases And Literature Review, Hussain Shallwani, Muhammad Zubair Tahir, Muhammad Ehsan Bari, Tanveer Ul Haq

Medical College Documents

Background: Concurrent intracranial and spinal arteriovenous malformations (AVMs) are very rare with only a few cases being reported in literature. Two of the rare concurrent intracranial and spinal AVM cases are presented.
Case description: Case 1 is a 12-year-old girl with headache and motor disturbances in the lower limbs. Her spinal and brain angiogram was done and she was diagnosed to have a spinal AVM at level T8-T9 and an intracranial AVM in the left mesial temporal lobe. Her spinal AVM was embolized, while no treatment was given for her intracranial AVM. Case 2 is a 10-year-old girl who presented …

Computer-Based Sex Education For High School Students, Ashley Jones

Evidence-Based Practice Project Reports

Adolescents are four times more likely than other age groups to contract chlamydia or gonorrhea. In the USA, young people between 15 to 24 years of age acquire almost half of all newly diagnosed sexually transmitted infections (STI) a year. The purpose of this computer-based sex education EBP project was to increase student knowledge regarding transmission, disease process, and treatment for STIs, as well as to reduce high risk sexual behaviors. The evidence-based practice model for change and the Modeling, Role-Modeling nursing theory guided this project. Computer-based sex education is supported in research. Articles critiqued, utilizing Melnyk and Fineout-Overholt (2011) …

Medical School Watercooler Newsletter - May 13, 2012, Lindsey Lyle

Watercooler Newsletter

This is the May 13, 2012 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Medical School Graduates Participate in Honors Convocation Ceremony
• Med School Café - Expert Advice for the Community
• Med Student Life: A Day with Russ Terry
• Snapshots: Children's & Women's Hospital Day
• USA Health System Implements EMR System
• Golf Tournament Proceeds Benefit USA Regional Burn Center

Get Your Butt Off The Ground!: Consequences Of Cigarette Waste And Litter-Reducing Methods, Joyce Lee

Pomona Senior Theses

Cigarette butts are rapidly accumulating on our planet; trillions of them are discarded every year. In this paper, I examine why cigarette litter is a problem. I first discuss the biodegradability of filters and its scientific basis, including ways to enhance degradation rates by chemically manipulating filters. I also talk about the persistence of cigarette chemicals and their potential toxic effects on children and animals. I consider other social, economic, and environmental consequences of cigarette filters and chemicals. Furthermore, I discuss various solutions smokers and non-smokers alike have created to address the problem of cigarette litter; these methods come from …