Medicine and Health Sciences Commons^™

Ada News - 04/21/2008, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

A Central Function For Perlecan In Skeletal Muscle And Cardiovascular Development, Jason J. Zoeller, Angela Mcquillan, John Whitelock, Shiu-Ying Ho, Renato V. Iozzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Perlecan's developmental functions are difficult to dissect in placental animals because perlecan disruption is embryonic lethal. In contrast to mammals, cardiovascular function is not essential for early zebrafish development because the embryos obtain adequate oxygen by diffusion. In this study, we use targeted protein depletion coupled with protein-based rescue experiments to investigate the involvement of perlecan and its C-terminal domain V/endorepellin in zebrafish development. The perlecan morphants show a severe myopathy characterized by abnormal actin filament orientation and disorganized sarcomeres, suggesting an involvement of perlecan in myopathies. In the perlecan morphants, primary intersegmental vessel sprouts, which develop through angiogenesis, fail …

Cobb, Sheila Marie (Fa 223), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid and full-text scan of paper (Click on “Additional Files” below) for Folklife Archives Project 223. Paper: "[Folk Medical Beliefs]" written by Sheila Marie Cobb for a Western Kentucky University folk studies class.

Searching The Collective Knowledge: Finding Evidence In The Medical, Nursing And Psychology Literature, Stephanie Wiegand

University Libraries Publications

Attendees will learn tips and tricks for search medical, nursing, and psychology literature. Discussion will include types of literature, reliability of literature, and approaches to gathering evidence to support healthcare change. Manage your time, know your librarian, construct a research question, know where to search, determine best search terms, and put your hands on (access) the evidence. Learn the difference between keyword and subject term searching and how to take advantage of these tools in various literature databases.

Intensive Care For Extreme Prematurity--Moving Beyond Gestational Age, Jon E Tyson, Nehal A Parikh, John Langer, Charles Green, Rosemary D Higgins

Faculty, Staff and Student Publications

BACKGROUND: Decisions regarding whether to administer intensive care to extremely premature infants are often based on gestational age alone. However, other factors also affect the prognosis for these patients.

METHODS: We prospectively studied a cohort of 4446 infants born at 22 to 25 weeks' gestation (determined on the basis of the best obstetrical estimate) in the Neonatal Research Network of the National Institute of Child Health and Human Development to relate risk factors assessable at or before birth to the likelihood of survival, survival without profound neurodevelopmental impairment, and survival without neurodevelopmental impairment at a corrected age of 18 to …

Productivity Spillovers In Healthcare: Evidence From The Treatment Of Heart Attacks, Amitabh Chandra, Douglas O. Staiger

Dartmouth Scholarship

A large literature in medicine documents variation across areas in the use of surgical treatments that is unrelated to outcomes. Observers of this phenomena have invoked “flat of the curve medicine” to explain these facts, and have advocated for reductions in spending in high-use areas. In contrast, we develop a simple Roy model of patient treatment choice with productivity spillovers that can generate the empirical facts. Our model predicts that high-use areas will have higher returns to surgery, better outcomes among patients most appropriate for surgery, and worse outcomes among patients least appropriate for surgery, while displaying no relationship between …

Short-Course Versus Long-Course Antibiotic Therapy For Non-Severe Community-Acquired Pneumonia In Children Aged 2 Months To 59 Months, Batool A. Haider, Muhammad Ammad Saeed, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: Pneumonia is the leading cause of mortality in children under five years of age. Treatment of pneumonia requires an effective antibiotic used in adequate doses for an appropriate duration. Recommended duration of treatment ranges between 7 and 14 days, but this is not based on any empirical evidence. Shorter duration of therapy, if found to be effective, could be particularly important in resource-poor settings where there is a high risk of death, poor access to medicines and health care, and limited budgets for medicines.
Objectives: To evaluate the efficacy of short- course versus long-course therapy with the same antibiotic …

Ms211: Letter From John Post To Armin & Karen, Armin Weinberg

Works on Radiation Effects: 1990-2020

This is a letter that accompanied a gift (tube with document inside that was printed by the original Gutenberg printing press) from John Post to Armin. John was a ret. Col. in medical logistics (at the US Dept of State) that helped distribute excess medical and hospital supplies to our AIHA partners in Kazakhstan, Azerbiajan and actually helped with shipment to Gaza as well. Since he lived in DC I invited him to a couple of the non-radiation related Intercultural Cancer Council Biennial Symposia that our Center at BCM coordinated. The page is now at the HRC for viewing. See …

Glynn, Luanne Carol Aylesworth (Fa 229), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid and full-text scan of paper (Click on “Additional Files” below) for Folklife Archives Project 229. Paper: "[Folk Medical Beliefs About Illness]" written by Luanne Carol Aylesworth Glynn for a Western Kentucky University folk studies class.

Edwards, Jennifer L. (Fa 220), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid and full-text scan of paper (Click on “Additional Files” below) for Folklife Archives Project 220. Paper: "Folk Medical Beliefs Concerning Colds or the Flu" written by Jennifer L. Edwards for a Western Kentucky University folk studies class.

Highlights: Analysis Of The Proposed Rule On Designation Of Medically Underserved Populations And Health Professional Shortage Areas, Peter Shin, Leighton C. Ku, Emily Jones, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

For decades, the federal government has targeted health care funding, resources and staff to meet the health care needs of areas designated as "medically underserved areas" and "health professional shortage areas." Areas that qualify may, for example, receive federal funding to support the establishment and operation of community health centers, or receive National Health Service Corps (NHSC) physicians and clinicians. In addition, physicians who practice in these health shortage areas may receive higher payments under Medicare. These designations thus affect the availability of health care in thousands of urban and rural areas all across the United States. Community health centers …

Analysis Of The Proposed Rule On Designation Of Medically Underserved Populations And Health Professional Shortage Areas, Peter Shin, Leighton C. Ku, Emily Jones, Sara J. Rosenbaum

Geiger Gibson/RCHN Community Health Foundation Research Collaborative

Numerous safety net programs and health care providers depend on Medically Underserved Area and Population (MUA/P) and Health Professional Shortage (HPSA) designations to qualify for federal funding, physician subsidies and placement, and health-related investments to improve access to care for communities and populations at high risk of poor health. These resources are particularly critical for federally-qualified health centers at a time when the number of uninsured is growing and the capacity of the safety net shrinking. On February 29, 2008, the Department of Health and Human Services (HHS) released a proposed regulation to alter the way these designations are made. …

2008 - The Thirteenth Annual Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Thirteenth Annual Symposium of Student Scholars, held on April 14, 2008. Includes abstracts from the presentations and posters.

Nonlinear Source-Filter Coupling In Phonation: Vocal Exercises, Ingo Titze, Tobias Riede, Peter Popolo

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Nonlinear source-filter coupling has been demonstrated in computer simulations, in excised larynx experiments, and in physical models, but not in a consistent and unequivocal way in natural human phonations. Eighteen subjects (nine adult males and nine adult females) performed three vocal exercises that represented a combination of various fundamental frequency and formant glides. The goal of this study was to pinpoint the proportion of source instabilities that are due to nonlinear source-tract coupling. It was hypothesized that vocal fold vibration is maximally destabilized when F0 crosses F1, where the acoustic load changes dramatically. A companion paper provides the theoretical underpinnings. …

Susceptibility Of Chlamydia Trachomatis To The Excipient Hydroxy-Ethylcellulose: Ph And Concentration Dependence Of Antimicrobial Activity, Ali A. Abdul-Sater, David M. Ojcius, M. P. Meyer

All Dugoni School of Dentistry Faculty Articles

Hydroxyethyl cellulose (HEC) is used as a neutral excipient in microbicides used against sexually transmitted pathogens. However, HEC inhibits the infection of cervical epithelial cells by Chlamydia trachomatis at pH 5 in a concentration-dependent manner. At pH 7, infection is inversely dependent on the concentration of HEC, possibly due to pH-dependent calcium sequestration.

Cost Saving By Reloading The Multiband Ligator In Endoscopic Esophageal Variceal Ligation: A Proposal For Developing Countries, Zaigham Abbas, Lubna Rizvi, Umair Syed Ahmed, Khalid Mumtaz, Wasim Jafri

Department of Medicine

Aim: To assess the cost savings of reloading the multiband ligator in endoscopic esophageal variceal ligation (EVL) used on the same patient for subsequent sessions.

Methods: This single centre retrospective descriptive study analysed patients undergoing variceal ligation at a tertiary care centre between 1st January, 2003 and 30th June, 2006. The multiband ligator was reloaded with six hemorrhoidal bands using hemorrhoidal ligator for the second and subsequent sessions. Analysis of cost saving was done for the number of follow-up sessions for the variceal eradication.

Results: A total of 261 patients underwent at least one session of endoscopic esophageal variceal ligation …

Learning On Line Using Wiki Technology: A Pilot Study In A Pediatric Clerkship, Anthony J. Frisby, J Lindsey Lane

The Selected Works of Anthony J. Frisby, PhD

Methods Students on the Pediatric Clerkship at Jefferson Medical College research case-vignettes in 20 topic areas and discuss their answers in small group with a faculty facilitator to achieve the learning objectives. Using the Blackboard course management system and Learning Objects TeamsLx software one topic area, with 10 case vignettes, was transferred to on line learning and piloted by 14 students divided into 5 groups. Instructions for use of the WIKI communication forum were provided on-line. Each group was assigned 2 case-vignettes. Outcomes data was obtained from questionnaires and student interviews.

Results: No student had prior experience with online learning. …

38th Annual Wku Student Research Conference, Student Research Council, Western Kentucky University

Student Research Conference Select Presentations

Western Kentucky University 38th Annual Student Research Conference program and student abstracts. Saturday, April 12, 2008, Carroll Knicely Conference Center, Bowling Green, Kentucky.

Searching For Binding Partners For The Novel Phkg1 Variant, Phkγ 181, Kishore Polireddy

Student Research Conference Select Presentations

Phopshorylase kinase (PhK) is a hexadecameric holoenzyme made up of four different subunits in the arrangement (αβγδ)4 and has total molecular mass of 1.3MDa. Alpha and β are regulatory subunits, γ is catalytic, and δ is an intrinsic molecule of calmodulin. PhK is a serine threonine kinase with glycogenolytic regulatory functions. Our lab has recently discovered that the γ subunit can be alternatively processed to produce a truncated form of 181 residues (γ-181). This variant of γ contains a phosphorylation site for PK-C, and its activity is influenced by this phosphorylation. We are using a LexA based yeast two hybrid …

Changing The Rules At The Drop Of A Hat: An Erp Study Of Preschoolers' Set-Shifting Ability, Sandra A. Wiebe, Daniel J. Carroll, Megan Herrington, Sari Raber, Kimberly A. Espy

Developmental Cognitive Neuroscience Laboratory: Faculty Publications

We examined the neural correlates of set-shifting in 5-year-old children and examined whether the ease of switching was affected by varying the number of non-switch trials preceding a switch.

Nuclear Energy, Steve Kraft

Native American Forum on Nuclear Issues

Abstract:

-Why Nuclear Energy?

-The lesson of the last 20 years in U.S. electricity policy:

– Diversified fuel and technology portfolio is essential

– All fuels and technologies (nuclear, coal, natural gas, renewables, efficiency) have a legitimate role

-The challenge for the future:

– Preserving/restoring diversified portfolio

– Ensuring resource adequacy, particularly in competitive markets

-Expanded use of nuclear energy is part of the answer

– Integrated used fuel management supports nuclear competitiveness

Nrc’S Decision Process: Judging The Safety Of A Proposed Repository, Janet Kotra

Native American Forum on Nuclear Issues

Abstract:

-Provide an overview of the role of the U.S. Nuclear Regulatory Commission (NRC) at Yucca Mountain

-Describe the process NRC will use to decide whether or not to authorize construction of a repository at Yucca Mountain

-Explain options and highlight important milestones that apply to Tribes as potential participants in NRC’s process

Native American Forum On Nuclear Issues Meet And Greet, Slideshow, And Attendance List

Native American Forum on Nuclear Issues

Slideshow, 58 PowerPoint slides & Attendance list

The Aging Services Network: Accomplishments And Challenges In Serving A Growing Elderly Population, Carol O'Shaughnessy

National Health Policy Forum

In 1965, Congress enacted the Older Americans Act, establishing a federal agency and state agencies to address the social services needs of the aging population. The mission of the Older Americans Act is broad: to help older people maintain maximum independence in their homes and communities and to promote a continuum of care for the vulnerable elderly. In successive amendments, the Act created area agencies on aging and a host of service programs. The “aging services network,” broadly described, refers to the agencies, programs, and activities that are sponsored by the Older Americans Act. The Act’s funding for services is …

Designing Non-Saccharide Heparin/Heparan Sulfate Mimics, Arjun Raghuraman

Theses and Dissertations

Glycosaminoglycans (GAGs) are complex biopolymers that play important roles in inflammation, coagulation, angiogenesis, cell adhesion and viral invasion by interacting with several different proteins.1,2 Structurally, GAGs are built up of several different sulfated disaccharide units.3 Specific GAG sequences that uniquely recognize their cognate proteins exist. Such specificity typically arises from the binding of unique sulfation patterns on the linear GAG chain to highly electropositive protein domains. Thus, these highly charged, sulfated biopolymers potentially represent a new class of therapeutics. Yet, the major stumbling block to the development to these agents is their extremely complicated and tedious chemical synthesis. We hypothesized …

Tribes And Yucca Mountain: Native American Forum On Nuclear Issues, Fred Dilger

Native American Forum on Nuclear Issues

Abstract:

-Yucca Mountain: Extensive history of social-cultural studies

-No interaction on transportation

-Unsuccessful effort began in 1993 and ended in 1995

-DOE tribal policy was a very good start

-Restarted again in 2004-DOE invites tribes to TEC meeting

-Shape future interaction between DOE and other Tribes

-Tribes identify themselves as affected by DOE differently than DOE defines affected tribes

Yucca Mountain- Could The End Be Near?, Steve Frishman

Native American Forum on Nuclear Issues

Presentation & Biography

Nuclear Risk Management For Native Communities, Ian Zabarte

Native American Forum on Nuclear Issues

Abstract:

-NCAC The Native Community Action Council (NCAC) is a grassroots organization of Western Shoshone and Southern Paiute peoples.

-A common need to address the adverse human health impacts known to be plausible from exposure to ionizing radiation.

Fighting Nuclear Waste At Skull Valley, Margene Bullcreek

Native American Forum on Nuclear Issues

Abstract:

-Reasons We Oppose Nuclear Waste

-Sovereignty

-Traditional values must be protected

-Protect sacredness of our culture, plants,

animals, air, and water

-Affects on community health

-Protect reservation and homeland

-To protect the air and water

-To protect future generations

-Environmental Justice

Native American Forum On Nuclear Issues Agenda

Native American Forum on Nuclear Issues

Conference agenda

Sponsored by: UNLV Department of Environmental Studies, UNLV Libraries, UNLV Department of History, UNLV Department of Sociology and the Native Community Action Council