Medicine and Health Sciences Commons^™

Self-Efficacy, Physical Activity, And Aerobic Fitness In Middle School Children: Examination Of A Pedometer Intervention Program, Dana M. Manley

Theses and Dissertations (ETD)

The purpose of this study was to examine the relationships among self-efficacy levels, physical activity, aerobic fitness, and body composition (relative body mass index; RBMI) and to determine whether a school-based pedometer intervention program would improve those variables and prevent weight gain in sixth and seventh graders in rural mid-South middle schools. Bandura’s Social Cognitive Theory served as the theoretical basis for the study.Methods: A quasi-experimental pre-test, post-test design was used. The sample, recruited from two rural middle schools in Kentucky, consisted of 116 sixth and seventh grade students (98% Caucasian, 51% male, age=11.65±0.71). Anthropometric assessment of height, weight, …

Molecular Profile Of Women With And Without Secondary Breast Cancer After The Treatment Of Pediatric Hodgkin Lymphoma, Belinda Neal Mandrell

Theses and Dissertations (ETD)

dentification of genetic risk factors associated with the development of secondary cancers would facilitate identification of at risk patients and permit modification of therapy and heightened surveillance that may reduce cancer-related morbidity and mortality. Women survivors of pediatric Hodgkin lymphoma (HL) have an increased risk of morbidity and mortality associated with secondary effects of therapy, with a 35-75 fold excess risk of developing breast cancer over the general population. The mechanism for secondary breast cancer among Hodgkin survivors is not understood. Researchers have postulated that the familial characteristics of HL could be associated with mutations found within familial cancer syndromes; …

Golgi Specificity And Development Of Autoreactive B Cells, Fazlullah Salar Khan Nawazi

Theses and Dissertations (ETD)

B cell receptors with certain heavy/light chain pairs predominate in the periphery of anti-DNA heavy chain transgenic mice while certain other B cell receptors are absent. We wanted to know why. To answer this, we re-constructed B cell receptors represented in the anti-DNA transgenic mice by cloning them as single chain variable fragments (scFv) to analyze their affinity to dsDNA. scFv representing receptors that were recovered from the spleens of transgenic mice had very little to no affinity to dsDNA. scFv representing receptors that were absent in the spleen had high affinity to dsDNA. We therefore concluded that receptors with …

Biochemical And Immunological Mechanisms Underlying Differential Interaction Of Superantigens With Host Immunogenetic Factors In Streptococcal Sepsis, Mohammed Nooh

Theses and Dissertations (ETD)

Group A streptococci (GAS) are serious human pathogens that can cause a wide array of diseases ranging from pharyngitis to streptococcal toxic shock (STSS), which is caused by excessive cytokines responses triggered by streptococcal superantigens (Strep SAgs). SAgs interact simultaneously with HLA class II molecules on antigen presenting cells (APC) and with the T cell receptor beta chain variable elements (TCR V) and cause excessive stimulation of both cell types and massive release of inflammatory mediators.

The Strep SAgs include the streptococcal pyrogenic exotoxins (Spes), which play a crucial role in the pathogenesis of severe invasive streptococcal diseases, including Strep …

Cephalometric Evaluation Of Bionator Therapy In The Early Treatment Of Class Ii Malocclusions, Daniel C. Sawrie

Theses and Dissertations (ETD)

Early or two-phase orthodontic treatment of Class II malocclusions is a debated topic in orthodontic circles primarily because the benefits of early intervention have not been consistently reproduced among researchers. The present study was a retrospective analysis of cephalograms from patients with Class II, division 1 malocclusions at the start of treatment. These were 50 consecutively treated youths who received phase 1 (early) treatment with a Bionator appliance and later treatment with full appliances (all treated by a single clinician). The comparison group consisted subjects treated in a single phase with fixed Edgewise appliances only. Importantly, subjects in the two …

Why Pharmacists Choose To Seek Or Not Seek Board Certification In Pharmacy Practice: A Comparison Of Motivation And Motivating Factors, Mark Tankersley

Theses and Dissertations (ETD)

The stated mission of the Board of Pharmaceutical Specialties (BPS) with regard to specialization is, via board certification, to recognize specialty areas, define skill standards for those specialty areas, and evaluate the knowledge and skills of individual Pharmacy specialists. The perceived or real benefits to the pharmacist of pursuing board certification are unknown. These benefits can be evaluated by separating into values (valences) and instrumentalities, the latter of which is the perceived or known probability that a performance will lead to an outcome. The primary purpose of this study was to determine the differences in values and instrumentalities perceived by …

Predictors Of Depressive And Anxiety Symptoms Among African American Hiv-Positive Women, Nina Katherine Sublette

Theses and Dissertations (ETD)

This descriptive correlation study had four purposes: describe depressive and anxiety symptom levels in pregnant and non-pregnant African American (AA) HIV-positive women, examine the association between underlying vulnerabilities and depressive symptoms in HIV-positive AA women, determine the association between underlying vulnerabilities and anxiety symptoms in AA HIV-positive women, and determine the predictors of depressive and anxiety symptoms among African American HIV-positive women. A convenience sample of 80 African American HIV-positive women was recruited from university-based obstetrics/-gynecology and infectious disease practices in a large metropolitan city in the Mid-South. Depressive symptoms were measured with the Center for Epidemiologic Studies Depression Scale …

Sleep, Fatigue And Caregiver Burden In Parents Of Children With Acute Lymphoblastic Leukemia (All), Jerithea Tidwell

Theses and Dissertations (ETD)

Parents often report that their child diagnosed with acute lymphoblastic leukemia (ALL) and receiving steroid therapy experience altered sleep patterns, fatigue, irritability, and other behavioral changes. As a consequence, parents may experience altered sleep, fatigue, and increased caregiver burden. If so, the differences seen in parental sleep efficiency and sleep duration may be attributed to the child experiencing altered sleep secondary to receiving dexamethasone. The purpose of this study was to describe, caregiver sleep, fatigue, and caregiver burden immediately before and during their child’s dexamethasone pulse in continuation therapy for ALL and to compare parent quality of sleep and fatigue …

The Structural And Functional Study Of Git1 Paxillin Binding Domain, Ziwei Zhang

Theses and Dissertations (ETD)

The G protein coupled receptor (GPCR)-kinase (GRK) interacting protein 1 (GIT1) is a multidomain protein that plays an important role in cell adhesion, motility, cytoskeletal remodeling, and membrane trafficking. GIT1 mediates the localization of p21-activated kinase (PAK) and PAK-interactive exchange factor (PIX) to focal adhesions, and its activation is regulated by the interaction between its C terminal paxillin-binding domain (PBD) and the LD motifs of paxillin.

In this dissertation, we determined the solution structure of rat GIT1 PBD by nuclear magnetic resonance (NMR) spectroscopy. The PBD folds into a four-helix bundle, which is structurally similar to the focal adhesion targeting …

Unusual Presentation Of Idiopathic Retroperitoneal Fibrosis: Case Report, N. Twahirwa, J. Rees

Imaging & Diagnostic Radiology, East Africa

Idiopathic retroperitoneal fibrosis (IRF) is an uncommon entity described as progressive proliferation of connective tissues leading to a fibrous plaque-like lesions that encases the aorta and inferior vena cava inferior to the level of the renal arteries. Mass forming retroperitoneal fibrosis is rare. We present a rare case of a unilateral focal retroperitoneal mass simulating a tumour encasing the middle third of the left ureter, with involvement of the ipsilateral scrotum.

Across The Pond: Ea-Ohp— Sohp Summit Meeting, Irvin Sam Schonfeld, Jonathan Houdmont

Publications and Research

On March 6, 2008 at the APA/NIOSH/SOHP Conference on Work, Stress, and Health in Washington, DC, the executive committees and other involved members of the Society for Occupational Health Psychology and the European Academy of Occupational Health Psychology held a summit meeting. The gathering was the latest in an ongoing series that began at the EA-OHP Dublin 2006 conference. The main discussion points and outcomes of interest to members are presented here.

New Fruit And Vegetable Offerings And Challenges Increased Lunch-Time Fruit And Vegetable Consumption Among Fourth-Graders, Cory Ann Hansen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Facilitating nutritional improvement in schools is an important strategy for reversing the alarming trends of overweight and undernourishment currently observed among children in the United States. Compared to national recommendations, many people in the United States under-consume nutrient-dense foods, such as fruits and vegetables. The objective of this study was to determine if various school-based interventions can increase fruit and vegetable consumption among 75 fourth-graders. Interventions included fruit and vegetable challenges, offering a new variety of fruit, and classroom nutrition education. To assess intake, photographs of students' school lunch trays were taken pre- and post-consumption and then analyzed to determine …

Refinement Of The Shared Care Instrument-Revised: A Measure Of A Family Care Interaction, Margaret Sebern

College of Nursing Faculty Research and Publications

This study’s purpose was to evaluate the psychometric properties of the Shared Care Instrument-Revised (SCI-R) in a sample of family care dyads. The SCI-R was developed to measure the construct of shared care, which is a system of three constructs (communication, decision making, reciprocity) used in family care to exchange support. An important aspect of evaluating the SCI-R was to create a measure that is statistically sound and meaningful for patient and caregivers. Surveys were mailed to randomly selected home health dyads, which included 223 patients and 220 caregivers. Reliability and confirmatory factor analysis, and concurrent validity were examined. Internal …

Inside Unlv, Grace Russell, Shane Bevell, Mamie Peers, Michelle Mouton

Inside UNLV

No abstract provided.

Effects Of N-3 Fatty Acids On Autoimmunity And Osteoporosis, Gabriel Fernandes, Arunabh Bhattacharya, Mizanur Rahman, Khaliquz Zaman, Jameela Banu

Health & Biomedical Sciences Faculty Publications

Decreased consumption of n-3 fatty acids (FA) and diets rich in animal proteins, saturated fats and n-6 vegetable oils are associated with a higher incidence of cardiovascular disease (CVD), certain malignancies and autoimmune disorders such as rheumatoid arthritis and Systemic Lupus Erythromatous (SLE), and renal disease. Recent studies show that reduced calorie intake and supplementation of diet with n-3 FA delays the onset of autoimmune renal disease, primarily, due to increased antioxidant enzyme activities, decreased NF-kappaB activation and decreased IL-1, IL-6 and TNF-alpha mRNA expression in the kidney tissue. Studies in rodents show that addition of n-3 FA and soy …

Lsuhsc Facilities Biweekly Update: May 2008, Lsuhsc Property And Facilities Management

LSUHSC Facilities Biweekly Updates: 2008

LSUHSC Facilities Biweekly Updates from May 9 and 23, 2008.

These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

Lsuhsc Facilities Daily Update: May 2008, Lsuhsc Property And Facilities Management

LSUHSC Facilities Daily Updates: 2008

LSUHSC Dailly Facilities Updates from May 2008. These updates describe damage and a timeline of repairs at the LSU Health Sciences Center - New Orleans campus due to Hurricane Katrina which made landfall August 29, 2005.

De Novo Primary Squamous Cell Carcinoma Of The Ovary: A Case Of A Rare Malignancy With An Aggressive Clinical Course, Ali Imran Amjad, Khawaja Muhammad Inam Pal

Section of General Surgery

Ovarian squamous cell carcinoma is a rare malignancy and the occurrence is attributable to malignant transformation of an existing ovarian dermoid cyst. The de novo occurrence of squamous cell carcinoma of the ovary, in the absence of an antecedent ovarian dermoid, is extremely rare. The case of a 31 year old Asian woman, evaluated for abdominal distension and discomfort is presented. Abdominal CT was suggestive of a malignant neoplastic process. Laparotomy confirmed a malignant tumour with involvement of the right adnexa and extension into the omentum and bowel. Surgical debulking, hysterectomy, bilateral salpingo-ophorectomy and total omentectomy and bowel resection was …

Intrasheath Subluxation Of The Peroneal Tendons., Steven M Raikin, Ilan Elias, Levon N Nazarian

Department of Radiology Faculty Papers

BACKGROUND: Dislocation or subluxation of the peroneal tendons out of the peroneal groove under a torn or avulsed superior peroneal retinaculum has been well described. We identified a new subgroup of patients with intrasheath subluxation of these tendons within the peroneal groove and with an otherwise intact retinaculum.

METHODS: The cases of fifty-seven patients with painful snapping of the peroneal tendons posterior to the fibula were reviewed. Of these, forty-three had tendons that could be reproducibly subluxated out of the groove with a dorsiflexion-eversion maneuver of the ankle. Fourteen patients who could not subluxate the tendons out of the groove …

Understanding "Sports Hernia" (Athletic Pubalgia) - The Anatomic And Pathophysiologic Basis For Abdominal And Groin Pain In Athletes, William C. Meyers, Edward Yoo, Octavia Devon, Nikhil Jain, Marcia Horner, Cato Lauencin, Adam Zoga

Department of Radiology Faculty Papers

Recent publicity and some scientific reports suggest increasing success in treating an entity called “sports hernia” - more accurately named athletic pubalgia. The primary purpose of this article is to portray what we believe to be the key concept for understanding this wide variety of abdominal and groin injuries that afflict high performance athletes. These injuries have been plaguing athletes for a long time, and past treatments, based on concepts of occult hernia or simple strains, have generally failed. The former concepts do not take into account the likely mechanisms of injury or various patterns of pain that these athletes …

Paripartum Cardiomyopathy: Implications For Nps, Jeffrey A. Goss, A. Elaine Bond, Renea L. Beckstrand, Lynn C. Callister

Faculty Publications

Peripartum cardiomyopathy (PPCM), the fifth leading cause of death in pregnancy, is often overlooked or misdiagnosed because of vague symptoms and a lack of specific criteria for diagnosis. The authors performed a literature review of articles published between January 2000 and November 2007, and found that early diagnosis via echocardiography and interventions with specific treatment modalities can reduce mortality. Dobutamine stress testing may be prognostic for left ventricular (LV) dysfunction. Standard heart failure (HF) drug regimens, heart transplantation, and mechanical assist devices are viable treatment modalities, depending on individual needs. Subsequent pregnancies must be followed closely. The authors recommend that …

Cardiac Tamponade After Removal Of Temporary Pace Maker In Multidiscipinary Intensive Care Unit, Muhammad Faisal Khan, Ali Bin Sarwar Zubairi

Department of Anaesthesia

Cardiac tamponade is a medical and surgical emergency, which needs early recognition and treatment. Myocardial perforation leading to cardiac tamponade is a rare complication after pace maker insertion. We are reporting a case of cardiac tamponade after removal of temporary pace maker in a multidisciplinary intensive care unit.

Primary Cutaneous B Cell Lymphoma--Leg Type (New Eortc--Who Classification), With Nasal Sinuses Involvement, Asim Jamal Shaikh, Nehal Masood, Aamir Ahsan, Wasim Memon

Department of Radiation Oncology

Primary Cutaneous lymphomas of B cell origin are rare, there remains a controversy in truly classifying these lymphomas and an updated EORTC classification divides them on the basis of their distinct histopthological grounds rather than on the basis of their anatomic location as in WHO classification, while the new WHO- EORTC joint classification maintains some characteristics of both systems, We report an elderly gentleman who primarily had a typical Leg dominant Cutaneous lymphoma of B cell origin uniquely with involvement of nasal Sinusues, bearing the Immunohistochemical staining features of "Cutaneous lymphoma - Leg Type" befitting the new joint WHO-EORTC classification …

Laryngotracheal Trauma: Its Management And Sequelae, Shabbir Akhtar, Sohail Awan

Section of Otolaryngology, Head & Neck Surgery

OBJECTIVE: Laryngotracheal trauma is a rare but clinically important injury. Complications are frequent. Early recognition, accurate evaluation and proper treatment is vital. In order to learn from our past experience and refine our management, we reviewed our cases.

METHODS: Fifteen patients with external laryngotracheal injuries were analyzed retrospectively. The outcome was assessed both in terms of voice and airway, on short term and long term basis.

RESULTS: Commonest cause of injury was cut throat injuries followed by road traffic accidents. The main presenting symptoms and signs were hoarseness, haemoptysis, odynophagia and stridor. Major laryngeal injuries (10 cases) outnumbered minor injuries …

Glenohumeral Joint Range Of Motion In Elite Male Golfers: A Pilot Study, Jason Brumitt, Erik Meria, Bob Nee, Greg Davidson

Faculty Publications - College of Physical Therapy

Background: Shoulder injuries account for up to 17% of all golf related musculoskeletal injuries. One cause may be the repetitive stresses applied to the lead shoulder during the backswing and follow-through phases, which may contribute to the frequency of these injuries. The “elite” golfer may be predisposed to developing a shoulder injury based upon the reported adaptations to the glenohumeral joint.

Objective: To examine and compare bilateral glenohumeral joint rotational range of motion in elite golfers using standard goniometric procedures.

Methods: Twenty-four “elite” male golfers were recruited for this study. Glenohumeral internal (IR) and external rotation (ER) passive range of …

Rhinosporidiosis Presenting As An Urethral Polyp, Najamul Sahar Azad, Zubairali Ahmad, Naila Kayani

Department of Pathology and Laboratory Medicine

Rhinosporidiosis is an inflammatory disease caused by Rhinosporidium seeberi, a protoctistan mesomycetozoa, member of a group of novel aquatic parasites, characterized by hyperplastic polypoid lesions of the nasal cavity and rarely other mucous membranes. We report an unusual presentation of rhinosporidiosis as an urethral polyp, which is only the second case of rhinosporidiosis reported from Pakistan.

Chest Radiograph After Central Line Placement Under Fluoroscopy: Utility Or Futility?, Scott J. Keckler, Troy L. Spilde, Brian Ho, Kuojen Tsao, Daniel J. Ostlie, G W. Holcomb Iii, Shawn D. St Peter

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Postoperative portable chest films are routinely performed after fluoroscopic placement of central venous catheters to evaluate positioning and to rule out significant complications (eg, pneumothorax). Emerging evidence in the literature has called this practice into question suggesting that routine postoperative chest x-ray is unnecessary. Therefore, we investigated our recent experience to examine the utility of these films, to examine the development of symptoms relative to therapeutic intervention, and to report a cost-benefit analysis.

METHODS: After obtaining institutional review board approval, all charts of patients undergoing central venous catheter placement from January 2004 to December 2005 at our institution were …

Lead-Associated Endocarditis: The Important Role Of Methicillin-Resistant Staphylococcus Aureus., Arnold J. Greenspon, Eugene S. Rhim, George Mark, Joseph Desimone, Reginald T. Ho

Division of Cardiology Faculty Papers

BACKGROUND: Infection is a potentially life-threatening complication of cardiac device implantation. Lead-associated endocarditis (LAE) may be the most serious complication since it is associated with a high mortality. METHODS: The medical records of patients referred to our institution for the treatment of LAE between 1999 and 2007 were reviewed. RESULTS: A total of 51 of 107 patients referred for device-related infections met the criteria for LAE. Of these, 19 occurred within 6 months of their most recent procedure (early), while the remaining 32 occurred more than 6 months later (mean = 31.9 months post procedure). Devices included pacemakers in 33 …

Nadph Oxidase In Pc12 Cell Differentiation And Apoptosis, Lina Begdache

Graduate Dissertations and Theses

Neuronal differentiation is an important process during human development and regenerative medicine. One factor linked to differentiation of neurons in vivo as well as in vitro is the generation of reactive oxygen species (ROS). In addition, neurodegeneration is the disease of the old age that is currently affecting millions. Although the etiology of each neurodegenerative disease differs, oxidative stress has been the common factor leading to neuronal death. PC12 cells differentiate into sympathetic-like neurons in the presence of nerve growth factor (NGF). Once terminally differentiated, PC12 cells undergo apoptosis following NGF deprivation with similar characteristics of sympathetic neuronal death. These …

Native American Flute Meditation: Musical Instrument Design, Construction And Playing As Contemplative Practice, Daniel Cummings

Senior Honors Projects

For almost two years now, I have been involved in hand-crafting and playing my own Native American-style flutes. In the course of that time, this hobby has gradually merged with my interests in mindfulness and meditation practices to produce a unique result, nearly a fully fledged form of contemplation in its own right. For me, flute making and playing have become inseparable and vital components of a seamless process, one whose various stages can all be undertaken as occasions for the application of meditative techniques. Defining meditation in essence as the expansion of awareness in any activity—whether focused on a …