Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

2007

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 2401 - 2430 of 3121

Full-Text Articles in Medicine and Health Sciences

The Distribution Of Bone Mineral Density In Healthy Women In Tehran, Hadi̇ Akhbari Jan 2007

The Distribution Of Bone Mineral Density In Healthy Women In Tehran, Hadi̇ Akhbari

Turkish Journal of Medical Sciences

Aim: Correct interpretation of Bone Mineral Densitometry (BMD) measurements requires a population-specific reference range. The aim of this study was to establish Dual Energy X-ray Absorptiometry (DEXA) BMD reference values for healthy women residing in Tehran. Materials and Methods: 566 healthy female volunteers aged 20-40 years from five district areas in Tehran participated in the study. BMD was determined by a LUNAR system. Measurement sites were the spine, femur, leg, arm, pelvis and total body. All measurements were performed by an experienced staff. Prior to each measurement, quality control testing was performed by using the spine phantom of known density. …


Risk Factors For Fecal Carriage Of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli And Klebsiella Spp. In The Community, Özlem Kurt Azap, Hande Arslan, Sedef Ö. Karaman, Turhan Togan Jan 2007

Risk Factors For Fecal Carriage Of Extended-Spectrum Beta-Lactamase Producing Escherichia Coli And Klebsiella Spp. In The Community, Özlem Kurt Azap, Hande Arslan, Sedef Ö. Karaman, Turhan Togan

Turkish Journal of Medical Sciences

Aim: Community-acquired infections caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria are an emerging problem. Digestive tract colonization is a prerequisite for infections by ESBL-producing microorganisms. The aim of this study was to determine the prevalence of and risk factors for fecal carriage of ESBL-producing Escherichia coli (E. coli) or Klebsiella spp. in the community. Materials and Methods: A total of 928 stool samples admitted to the laboratory during a four-month period were included in the study. Samples were diluted in saline and cultured in two EMB agar plates supplemented with either 1 µg/ml cefotaxime or 1 µg/ml ceftazidime. All isolates that …


The Role Of Periodontal Disease On Acute Phase Proteins In Patients With Coronary Heart Disease And Diabetes, Gonca Çayir Keleş, Burcu Özkan Çeti̇nkaya, Selen Burçak Şi̇mşek, Di̇yar Köprülü, Hakki Kahraman Jan 2007

The Role Of Periodontal Disease On Acute Phase Proteins In Patients With Coronary Heart Disease And Diabetes, Gonca Çayir Keleş, Burcu Özkan Çeti̇nkaya, Selen Burçak Şi̇mşek, Di̇yar Köprülü, Hakki Kahraman

Turkish Journal of Medical Sciences

Aims: Chronic infections such as periodontal disease (PD) have been suggested to be a risk factor for coronary heart disease (CHD). Elevated levels of acute phase proteins are associated with increased risk for cardiovascular events in both healthy individuals and patients with known CHD. This study aimed to investigate the role of PD on C-reactive protein (CRP) and fibrinogen levels in patients with either CHD or type 2 diabetes. Materials and Methods: 80 subjects were evaluated in four groups: individuals with CHD+PD (group 1; n: 20), individuals with type 2 diabetes+PD (group 2; n: 20), individuals with PD without any …


Pregnancy Associated Plasma Protein-A And Epilepsy, Abdurrahman Coşkun, Burcu Özdemi̇rli̇, Ramazan Memi̇şoğullari Jan 2007

Pregnancy Associated Plasma Protein-A And Epilepsy, Abdurrahman Coşkun, Burcu Özdemi̇rli̇, Ramazan Memi̇şoğullari

Turkish Journal of Medical Sciences

In this study, we aimed to investigate the role of pregnancy-associated plasma protein-A (PAPP-A) as insulin-like growth factor binding protein-4 (IGFBP-4) protease in epilepsy patients. We studied 16 epilepsy patients and 10 healthy controls. Serum PAPP-A levels of epilepsy patients (6.8 ± 3.2 mU/L) were higher than of the control group (5.1 ± 1.9 mU/L), but the difference was not statistically significant (P > 0.05). We concluded that PAPP-A may increase the bioavailability of insulin-like growth factors (IGFs) due to decreased neurogenesis and synthesis of IGFs in chronically epilepsy patients.


Water Sorption And Solubility Of Different Luting And Restorative Dental Cements, Fi̇li̇z Keyf, S. Hakan Tuna, Murat Şen, Agnes Safrany Jan 2007

Water Sorption And Solubility Of Different Luting And Restorative Dental Cements, Fi̇li̇z Keyf, S. Hakan Tuna, Murat Şen, Agnes Safrany

Turkish Journal of Medical Sciences

Aim: The purpose of this study was to compare the water sorption and solubility of four provisional, three permanent luting cements and five restorative cements. Methods: A split ring mould was fabricated for the preparation of specimen discs which were 15.0 mm in diameter and 1.5 mm thick. All specimens were manipulated according to the manufacturer's instructions and then subjected to water sorption and solubility tests. Data were analysed with Wilcoxon Signed Ranks Test. Scanning electron microscopy was used to evaluate surface topography and roughness. Results: All tested materials demonstrated different degrees of sorption and solubility. The difference between sorption …


Brain Perfusion Single-Photon Emission Computed Tomography Findings In A Patient With Aicardi Syndrome, Mustafa Aydin, Tansel Ansal Balci, Ni̇met Kabakuş Jan 2007

Brain Perfusion Single-Photon Emission Computed Tomography Findings In A Patient With Aicardi Syndrome, Mustafa Aydin, Tansel Ansal Balci, Ni̇met Kabakuş

Turkish Journal of Medical Sciences

Aicardi syndrome is a rare X-linked dominant genetic disorder characterized by infantile spasms, agenesis or hypogenesis of the corpus callosum, and chorioretinal lacunae. There remain many unresolved questions regarding the clinical features of this disorder. Recent advancements in neuroimaging techniques have allowed us to obtain information about brain development and perfusion. Thus, we present herein the brain single-photon emission computed tomography (SPECT) findings in a 15-month-old female with Aicardi syndrome, which revealed that perfusion had shifted from the posterior to anterior regions. Furthermore, the right temporal lobe was not visualized, while significant hypoperfusion was determined on the occipital regions and …


The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden Jan 2007

The Role Of Heart-Type Fatty Acid-Binding Protein (H-Fabp) In Acute Myocardial Infarction (Ami) Compared To Conventional Cardiac Biochemical Markers, Hati̇ce Paşaoğlu, Ebru Ofluoğlu, Mustafa İlhan, Ati̇ye Çengel, Murat Özdemi̇r, Emre Durakoğlugi̇l, Murat Erden

Turkish Journal of Medical Sciences

Aim: To investigate the clinical implications of serum heart-type fatty acid-binding protein (H-FABP) compared to myoglobin, cardiac troponin I (cTnI), and creatine kinase MB isoenzyme (CK-MB) in patients with early phase acute myocardial infarction (AMI). Material and Methods: Patients were grouped clinically according to the American College of Cardiology/European Society of Cardiology new definition of myocardial infarction (MI) and by clinician diagnosis of MI. Serum concentrations of H-FABP, myoglobin, cTnI, and CK-MB were determined in 21 patients with AMI and 44 non-AMI patients. From each patient 3 blood samples were obtained 1-2, 3, and 6 h after the onset chest …


Comparison Of Conventional Cytogenetic And Fluorescence In Situ Hybridization Results Of Prenatal Aneuploidy Screening, Zerri̇n Yilmaz, Özge Özalp, Ebru Tarim, Ayla Üçkuyu, Vural Dağli, Feri̇de İffet Şahi̇n Jan 2007

Comparison Of Conventional Cytogenetic And Fluorescence In Situ Hybridization Results Of Prenatal Aneuploidy Screening, Zerri̇n Yilmaz, Özge Özalp, Ebru Tarim, Ayla Üçkuyu, Vural Dağli, Feri̇de İffet Şahi̇n

Turkish Journal of Medical Sciences

Background and Aim: Prenatal diagnosis of chromosome abnormalities is usually performed on amniotic fluid samples. Aneuploidy screening by fluorescence in situ hybridization (FISH), although not an alternative for conventional cytogenetics, has become a useful tool. Materials and Methods: We compared the results of FISH and conventional cytogenetic analysis applied on 51 amniotic fluid samples between January 2002 and December 2005, in our Cytogenetics Laboratory. Amniocytes were extracted using 5 cc of the sample, and direct FISH was applied using an AneuVysion Assay Kit (Vysis). The remaining fluid samples were used for chromosome analysis by conventional methods after long-term cell cultures. …


Increased Lipid Peroxidation And Decreased Antioxidant Response In Serum And Cerebrospinal Fluid In Acute Ischemic Stroke, Abdulkadi̇r Yildirim, Di̇lcan Kotan, Serap Yildirim, Recep Aygül, Fati̇h Akçay Jan 2007

Increased Lipid Peroxidation And Decreased Antioxidant Response In Serum And Cerebrospinal Fluid In Acute Ischemic Stroke, Abdulkadi̇r Yildirim, Di̇lcan Kotan, Serap Yildirim, Recep Aygül, Fati̇h Akçay

Turkish Journal of Medical Sciences

Background and Aim: The pathogenesis of brain damage in ischemic stroke is highly complex. The aim of the present study was to investigate the presence of oxidative stress in ischemic stroke and to determine whether the measured oxidative stress markers in serum and cerebrospinal fluid (CSF) were associated with infarction volume, and the Glasgow Coma Scale (GCS) and Glasgow Outcome Scale (GOS). Materials and Methods: The study included 32 patients with acute ischemic stroke within 48 h of onset and 18 suitable controls. Superoxide dismutase (SOD) and glutathione peroxidase (GPX) activity, glutathione (GSH) and malondialdehyde (MDA) level, and total antioxidant …


A Copper Determination Method Based On The Reaction Between 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N- Sulfopropylamino) Phenol (Nitro-Paps) And Copper For Use In Urine Copper Measurement And Application To Automation, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe Jan 2007

A Copper Determination Method Based On The Reaction Between 2-(5-Nitro-2-Pyridylazo)-5-(N-Propyl-N- Sulfopropylamino) Phenol (Nitro-Paps) And Copper For Use In Urine Copper Measurement And Application To Automation, Osman Meti̇n İpçi̇oğlu, Ömer Özcan, Mustafa Gültepe

Turkish Journal of Medical Sciences

Aim: To develop a sensitive automated colorimetric urine copper determination method using a water soluble compound, 2-(5-nitro-2-pyridylazo)-5-(N-propyl-N-sulfopropylamino) phenol (nitro-PAPS), as a ligand. Materials and Methods: The new photometric method using sodium dodecyl sulfate (SDS)-ascorbic acid to dissociate copper from proteins in acetate buffer (pH 3.2) and nitro-PAPS as ligand was also adapted to an automated analyzer. Copper concentrations were determined by atomic absorption spectrophotometric method and by photometric method in 24 h urine samples of patients (n = 100) with various types of diseases including Wilson's disease (n = 12), diabetes mellitus (n = 34), osteoporosis (n = 27), nephrotic …


Development Of A Highly Sensitive Elisa For Quantification Of Hepatitis B Virus (Hbv) Surface Antigen (Hbsag), Resul Karakuş, Lati̇fe Arzu Aral, Bi̇lkay Baştürk, Cemaletti̇n Aybay Jan 2007

Development Of A Highly Sensitive Elisa For Quantification Of Hepatitis B Virus (Hbv) Surface Antigen (Hbsag), Resul Karakuş, Lati̇fe Arzu Aral, Bi̇lkay Baştürk, Cemaletti̇n Aybay

Turkish Journal of Medical Sciences

Background: Hepatitis B Virus (HBV) infection is of global importance and many studies are aimed to develop more sensitive diagnostic tools and improve therapeutic options. HBV infection is diagnosed and followed-up basically by serological studies, among which the enzyme-linked immunosorbent assay (ELISA) is widely used. Aim: To develop a sensitive HBsAg ELISA for both research and diagnostic purposes. Materials and Methods: A hybridoma (clone 4D1) secreting anti-HBs IgG2a monoclonal antibody (mAb) was used for the establishment of our in-house ELISA. Tests were performed for both cell culture medium and human sera. The hepatoma cell lines of human origin PLC/PRF/5 and …


Prevention Of Adhesions By Omentoplasty: An Incisional Hernia Model In Rats, Bülent Aydinli, Gürkan Öztürk, Mahmut Başoğlu, S. Selçuk Atamanalp, M. İlhan Yildirgan, K. Yalçin Polat, Mehmet Öztürk, Cemal Gündoğdu, Durkaya Ören Jan 2007

Prevention Of Adhesions By Omentoplasty: An Incisional Hernia Model In Rats, Bülent Aydinli, Gürkan Öztürk, Mahmut Başoğlu, S. Selçuk Atamanalp, M. İlhan Yildirgan, K. Yalçin Polat, Mehmet Öztürk, Cemal Gündoğdu, Durkaya Ören

Turkish Journal of Medical Sciences

Background and Aim: Adhesion formation following abdominal wall hernia repair with prosthetic mesh may lead to intestinal obstruction and enterocutaneous fistulae. The purpose of this study was to compare the efficacy of fibrin glue (FG) and omentoplasty in the prevention of adhesion formation in a polypropylene mesh (PPM) abdominal wall replacement model. Materials and Methods: The study consisted of 3 groups of rats. A full-thickness abdominal wall defect was replaced with PPM. The control group (group 1) had no further treatment. The under surface of the PPM was covered with human FG in the FG group (group 2) and with …


Ultrasonographic Mapping Reduces The Complications Of Diagnostic Laparoscopy For Abdominal Tuberculosis, Müjdat Balkan, Arzu Balkan, Taner Yi̇ği̇t, Mutlu Sağlam, Yüksel Ateş, Ahmet Tüzün Jan 2007

Ultrasonographic Mapping Reduces The Complications Of Diagnostic Laparoscopy For Abdominal Tuberculosis, Müjdat Balkan, Arzu Balkan, Taner Yi̇ği̇t, Mutlu Sağlam, Yüksel Ateş, Ahmet Tüzün

Turkish Journal of Medical Sciences

Background and Aim: Diagnostic laparoscopy is of great value in the early diagnosis of abdominal tuberculosis and to help improve bed turnover. Diagnostic laparoscopy, however, is subject to all the risks and complications inherent to any invasive procedure. Our aim was to evaluate the role of ultrasonography in the prevention of complications when using diagnostic laparoscopy, and to present its efficacy in the monitoring of response to therapy. Materials and Methods: Nineteen male patients who had ascites with unknown etiology or with suspected abdominal tuberculosis were recruited. In order to analyze the potential role of ultrasonographic mapping as an aid …


Ogilvie`S Syndrome: Presentation Of 15 Cases, S. Selçuk Atamanalp, M. İlhan Yildirgan, Mahmut Başoğlu, Bülent Aydinli, Gürkan Öztürk Jan 2007

Ogilvie`S Syndrome: Presentation Of 15 Cases, S. Selçuk Atamanalp, M. İlhan Yildirgan, Mahmut Başoğlu, Bülent Aydinli, Gürkan Öztürk

Turkish Journal of Medical Sciences

Background: Ogilvie's syndrome is characterized by acute, massive colonic dilatation, without any mechanical obstruction. Methods: The records of 15 patients with Ogilvie's syndrome were retrospectively reviewed with respect to gender, age, associated problems, symptom duration, symptoms, signs, treatment, morbidity, mortality, and recurrence. Results: Mean age of the patients (8 male, 7 female) was 49.9 years (range: 32-76 years). Among them, 5 had medical problems, while 4 patients had had abdominal surgery, and 2 patients had burns. Mean symptom duration was 2.9 days (range: 1-7 days). The most common symptoms were abdominal pain and distention, while the most common signs were …


A Torsioned And Autoamputated Ovarian Cyst Simulating A Duplication Cyst: A Case Report, Sema Uğuralp, Bi̇rsen Harma, Ahmet Siğirci, Neşe Karadağ Jan 2007

A Torsioned And Autoamputated Ovarian Cyst Simulating A Duplication Cyst: A Case Report, Sema Uğuralp, Bi̇rsen Harma, Ahmet Siğirci, Neşe Karadağ

Turkish Journal of Medical Sciences

The commonest and most serious complication of neonatal ovarian cysts is torsion. Ovarian torsion leads to loss of the ovary. We report a case of a torsioned and autoamputated right ovarian cyst presenting as a duplication cyst of the intestine in a newborn. An abdominal cystic mass 4.8 x 3.4 cm in diameter was diagnosed in a 36-week-gestation fetus using antenatal ultrasonography (US). The physical examination revealed a mobile abdominal mass in the right upper quadrant. Postnatal US confirmed a cystic mass in the right upper quadrant. Intraoperatively, the ovarian cyst was autoamputated and it was adhered to the antimesenteric …


How To Manage Triquetrum And Hamate Fractures In Unusual Patterns: A Case Report, Vuslat Sema Ünal, Fuad Öken, Özgür Yildirim, Murat Gülcek, Zafer Soydan, Ahmet Uçaner Jan 2007

How To Manage Triquetrum And Hamate Fractures In Unusual Patterns: A Case Report, Vuslat Sema Ünal, Fuad Öken, Özgür Yildirim, Murat Gülcek, Zafer Soydan, Ahmet Uçaner

Turkish Journal of Medical Sciences

The 3-dimensional alignment of the carpal bones should be intact to ensure functional integrity of the hand. The treatment of fractures of the carpal bones is challenging and may differ according to localization. A patient with closed carpal injury and his treatment are presented in this report. After his wrist was crushed between a smooth hammer and a workbench during an occupational accident, the patient had multiple carpal bone fractures and remarkable swelling. The type of the injury was regarded to be a sort of capitate-hamate diastasis, although it did not correspond to any type that had been previously described. …


Ghrelin May Be A Universal Peptide In All Living Organisms, Süleyman Aydin Jan 2007

Ghrelin May Be A Universal Peptide In All Living Organisms, Süleyman Aydin

Turkish Journal of Medical Sciences

No abstract provided.


Editorial, M. Mahi̇r Özmen Jan 2007

Editorial, M. Mahi̇r Özmen

Turkish Journal of Medical Sciences

No abstract provided.


Editorial, Şi̇nasi̇ Özsoylu Jan 2007

Editorial, Şi̇nasi̇ Özsoylu

Turkish Journal of Medical Sciences

No abstract provided.


Correlations Of Serum Il-6 Levels And Prolidase Activity Between Bone Turnover Markers And Bone Mineral Density In Postmenopausal Women With And Without Osteoporosis, Aysun Toker, Hülya Aksoy, Bünyami̇n Börekçi̇, Asuman Özkan Jan 2007

Correlations Of Serum Il-6 Levels And Prolidase Activity Between Bone Turnover Markers And Bone Mineral Density In Postmenopausal Women With And Without Osteoporosis, Aysun Toker, Hülya Aksoy, Bünyami̇n Börekçi̇, Asuman Özkan

Turkish Journal of Medical Sciences

Aim: The purpose of this study was to measure serum prolidase activity and interleukin-2 and 6 (IL-2, IL-6) levels and to investigate the relationship of these parameters with bone mineral density (BMD) and bone turnover markers in postmenopausal women with and without osteoporosis. Materials and Methods: 59 postmenopausal women were included in this study (21 women with osteoporosis and 38 without). Serum IL-2 and IL-6 levels, prolidase activity, osteocalcin (OSC), calcium (Ca), alkaline phosphatase (ALP), urinary deoxypyridinoline (DPD) and BMD were measured in postmenopausal women with and without osteoporosis. Results: Serum prolidase activity was slightly higher in postmenopausal nonosteoporotic women …


A Role Of Leptin In Psoriasis?, Şebnem Aktan, Si̇mi̇n Rota, Berna Şanli Erdoğan, Şeni̇z Ergi̇n, Bünyami̇n Kaptanoğlu, Mehmet Bostanci Jan 2007

A Role Of Leptin In Psoriasis?, Şebnem Aktan, Si̇mi̇n Rota, Berna Şanli Erdoğan, Şeni̇z Ergi̇n, Bünyami̇n Kaptanoğlu, Mehmet Bostanci

Turkish Journal of Medical Sciences

Aim: Although there is evidence of a positive association between psoriasis and body mass index (BMI) and leptin is known to play a part in the regulation of the immune system, the relationship between psoriasis and leptin is still not well known. The aim of this study was to evaluate the possible relation between leptin and psoriasis. Materials and Methods: Serum leptin concentrations and BMI in 20 patients with psoriasis were compared to 20 age- and sex-matched healthy volunteers. Results: There was no difference between serum leptin levels of psoriatic patients (32.3 ± 24.9 ng/ml) and controls (36.8 ± 28.2 …


Evaluation Of The Ehrlich-Ziehl-Neelsen (Ezn) And Amplified Mycobacterium Tuberculosis Direct Test According To The Bactec Method In Respiratory And Nonrespiratory Samples, Tuncer Özeki̇nci̇, Sevi̇m Meşe, Selahatti̇n Atmaca, Nezahat Akpolat, Kadri̇ Gül Jan 2007

Evaluation Of The Ehrlich-Ziehl-Neelsen (Ezn) And Amplified Mycobacterium Tuberculosis Direct Test According To The Bactec Method In Respiratory And Nonrespiratory Samples, Tuncer Özeki̇nci̇, Sevi̇m Meşe, Selahatti̇n Atmaca, Nezahat Akpolat, Kadri̇ Gül

Turkish Journal of Medical Sciences

Aim: Tuberculosis remains a significant and threatening disease, particularly in developing countries. Mycobacterium tuberculosis should be detected and identified as soon as possible to ensure the prevention of the spread of the disease. For this purpose, use of fast and reliable laboratory diagnostic methods with high sensitivity and specificity was initiated in recent years. Materials and Methods: In this study, 107 respiratory and 198 nonrespiratory (305 in total) samples submitted to Dicle University Faculty of Medicine Clinical Microbiology Laboratory were examined using the Ehrlich-Ziehl-Neelsen (EZN), BACTEC 460 TB (Becton and Dickinson Diagnostic Instrument System, Towson, MD), and MTD (Amplified Mycobacterium …


Effects Of Cooking Techniques On Antioxidant Enzyme Activities Of Some Fruits And Vegetables, İmge B. Ergüder, Aslihan Avci, Erdi̇nç Devri̇m, İlker Durak Jan 2007

Effects Of Cooking Techniques On Antioxidant Enzyme Activities Of Some Fruits And Vegetables, İmge B. Ergüder, Aslihan Avci, Erdi̇nç Devri̇m, İlker Durak

Turkish Journal of Medical Sciences

Aim: The aim of this study was to investigate possible effects of cooking techniques on antioxidant enzyme activities in broccoli, tomato, red cabbage, parsley, carrot, green pepper, lemon, onion, and garlic, which are consumed frequently in our daily diet. Materials and Methods: Superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and catalase (CAT) activities were measured in fresh and thermally treated (boiling, microwaving and baking) fruits and vegetables. Results: When compared to raw vegetables, SOD, CAT and GSH-Px activities were found to diminish in most of the thermally treated vegetables except tomato, in which GSH-Px and CAT activities were found to increase. …


Clinical Features, Eeg Findings And Outcome In Patients With Bilateral Periventricular Nodular Heterotopia And Epilepsy, Aysun Ünal, Serap Saygi Jan 2007

Clinical Features, Eeg Findings And Outcome In Patients With Bilateral Periventricular Nodular Heterotopia And Epilepsy, Aysun Ünal, Serap Saygi

Turkish Journal of Medical Sciences

Aim: To review the clinical, electrophysiological and neuroimaging data of eight adult patients (4F/4M) with epilepsy and bilateral periventricular nodular heterotopia (PNH) after a long duration of follow-up. Materials and Methods: The clinical charts were reviewed for demographic and clinical features, seizure types and frequency, treatment and prognosis of all eight patients who were under follow-up by one of the authors (SS). The recordings of video-EEG monitoring with scalp electrodes in five patients and routine EEGs in all patients were reviewed. Results: The clinical semiology was in accord with seizures originating from temporal lobe region in four patients, while an …


Chromosome And P63 Gene Analysis Of An Infant With Ectrodactyly–Split Hand And Foot Malformation, Osman Demi̇rhan, Deni̇z Taştemi̇r, Nejat Narli, Süreyya Soyupak, Kenan Özcan Jan 2007

Chromosome And P63 Gene Analysis Of An Infant With Ectrodactyly–Split Hand And Foot Malformation, Osman Demi̇rhan, Deni̇z Taştemi̇r, Nejat Narli, Süreyya Soyupak, Kenan Özcan

Turkish Journal of Medical Sciences

Aim: Split hand-split foot malformation (SHFM) results from central ray reduction and presents as median clefts of the hands and feet, syndactyly, aplasia or hypoplasia of the phalanges, metacarpals and metatarsals, which are frequently associated with other phenotypic abnormalities. We aimed to investigate the genetic pathway of SHFM in a child. Materials and methods: Cytogenetic and molecular genetic analysis was performed in a 10-day-old boy with split-syndactyly hand and flat-syndactyly foot. Results: We found a complex chromosomal rearrangement including breaks in 4q12, fragility in the 9q11-13 band region and 9qh+. Cytogenetic results agree with the literature findings. The mutation analysis …


A Rare Side Effect Of Metformin: Metformin-Induced Hepatotoxicity, Ersi̇n Aksay, Sedat Yanturali, Başak Bayram, Ni̇l Hocaoğlu, Selahatti̇n Kiyan Jan 2007

A Rare Side Effect Of Metformin: Metformin-Induced Hepatotoxicity, Ersi̇n Aksay, Sedat Yanturali, Başak Bayram, Ni̇l Hocaoğlu, Selahatti̇n Kiyan

Turkish Journal of Medical Sciences

Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.


Giant Hydronephrosis Mimicking An Intraabdominal Mass, Turgut Yapanoğlu, Fati̇h Alper, İsa Özbey, Yilmaz Aksoy, Azam Demi̇rel Jan 2007

Giant Hydronephrosis Mimicking An Intraabdominal Mass, Turgut Yapanoğlu, Fati̇h Alper, İsa Özbey, Yilmaz Aksoy, Azam Demi̇rel

Turkish Journal of Medical Sciences

Giant hydronephrosis (GH) is a rare entity that may mimic progressive and benign abdominal cystic tumors. Despite the increase in the use of prenatal ultrasound, GH may still be seen in the adult population. We report a case of GH in a 19-year-old female who presented with a progressive abdominal distention and other gastrointestinal symptoms. Diagnostic and therapeutic features of this rare case are discussed in light of the current literature.


Horner´S Syndrome Post-Excision Of A Huge Cervical Sympathetic Chain Schwannoma, Sedat Aydin, Ari̇f Şanli, Ömer Taşdemi̇r, Ayli̇n Ege Gül Jan 2007

Horner´S Syndrome Post-Excision Of A Huge Cervical Sympathetic Chain Schwannoma, Sedat Aydin, Ari̇f Şanli, Ömer Taşdemi̇r, Ayli̇n Ege Gül

Turkish Journal of Medical Sciences

Schwannoma of the cervical sympathetic chain is a rare nerve tumor. These lesions typically present as an asymptomatic neck mass and are easily mistaken for a carotid body tumor during the initial work-up. In this report, a rarely seen huge cervical sympathetic chain schwannoma case, who experienced partial Horner´s syndrome postoperatively, is presented. We report a case of schwannoma on the cervical sympathetic chain, which to our knowledge is the largest reported in the current literature.


Intussusception Due To Inflammatory Fibroid Polyp Located At Ileum: Report Of Two Cases, Özgür Korkmaz, Hati̇ce Gülşen Yilmaz, Fahri̇ Yilmaz Jan 2007

Intussusception Due To Inflammatory Fibroid Polyp Located At Ileum: Report Of Two Cases, Özgür Korkmaz, Hati̇ce Gülşen Yilmaz, Fahri̇ Yilmaz

Turkish Journal of Medical Sciences

Inflammatory fibroid polyps are uncommon gastrointestinal tract lesions. The stomach and ileum are the most commonly affected sites. Clinical symptoms depend on the location and size of the lesion. Obstruction or intussusception is the most frequent initial symptom when an inflammatory fibroid polyp is located in the small intestine. We describe two cases of inflammatory fibroid polyps of the small intestine causing ileocecal and ileoileal intussusception.


The Nature Of Medical Evidence And Evidence-Based Practice, John A. Murie Jan 2007

The Nature Of Medical Evidence And Evidence-Based Practice, John A. Murie

Turkish Journal of Medical Sciences

No abstract provided.