Medicine and Health Sciences Commons^™

Fostering Aging In Place: "Healthy Naturally Occurring Retirement Community" (H-Norc) Qualities In A Southwest Ohio Suburb, Laura A. Previll

Master of Public Health Program Student Publications

This community assessment uses the concept of “H-NORCs” or Healthy Naturally Occurring Retirement Communities as a framework to analyze supports for aging (Masotti, Johnson-Masotti, Fick, & MacLeod, 2006) in Kettering, Ohio -- a first tier suburb of Dayton where the proportion of people over the age of 60 was 23.8% in 2010. In this study, I used focus groups and interviews to collect qualitative data on five H-NORC attributes: (1) economic policies that benefit seniors; (2) types of transportation support for seniors; (3) neighborhood design for physical activity; (4) opportunities for social integration and sense of belonging; and (5) health …

Effects Of Moderate Swim Exercise On Adiposity And Metabolic Function In Mice, Roberta L. Pohlman, Ana Carneiro, Vera Farah, Lynn K. Hartzler, Mariana Morris

Biological Sciences Faculty Publications

No abstract provided.

Effect Of Synthetic Aβ Peptide Oligomers And Fluorinated Solvents On Kv1.3 Channel Properties And Membrane Conductance, Maria I. Lioudyno, Matteo Broccio, Yuri Sokolov, Suhail Rasool, Jessica Wu, Michael T. Alkire, Virginia Liu, J. Ashot Kozak, Philip R. Dennison, Charles G. Glabe, Mathias Lösche, James E. Hall

Neuroscience, Cell Biology & Physiology Faculty Publications

The impact of synthetic amyloid β (1–42) (Aβ_1–42) oligomers on biophysical properties of voltage-gated potassium channels Kv 1.3 and lipid bilayer membranes (BLMs) was quantified for protocols using hexafluoroisopropanol (HFIP) or sodium hydroxide (NaOH) as solvents prior to initiating the oligomer formation. Regardless of the solvent used Aβ_1–42 samples contained oligomers that reacted with the conformation-specific antibodies A11 and OC and had similar size distributions as determined by dynamic light scattering. Patch-clamp recordings of the potassium currents showed that synthetic Aβ_1–42 oligomers accelerate the activation and inactivation kinetics of Kv 1.3 current with no significant effect …

Wright State University Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts Friday, April 13, 2012, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 13, 2012.

Proceedings - Wright State University Boonshoft School Of Medicine Fourth Annual Medical Student Research Symposium: Celebrating Medical Student Scholarship, Office Of Research Affairs, Boonshoft School Of Medicine

Medical Student Research Symposium Proceedings

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Fourth Annual Boonshoft School of Medicine Medical Student Research Symposium held on April 5, 2012.

Eti‐385 As A Novel Anti‐Emetic Against Drug Induced Emesis, Theresa Fennell, James Lucot, Samantha Spitak, Emily Smith, Teresa Garret

Symposium of Student Research, Scholarship, and Creative Activities Materials

Drugs currently used to prevent emesis (nausea and vomiting) target only one or a few of the pathways used by emetic stimuli to trigger the reflex. Thus, an anti-emetic drug will only be effective against some stimuli. Prior work determined that 8-OH-DPAT (DPAT, a 5-HT1A agonist) was a universally effective anti-emetic. Although DPAT prevented emesis, it also elicited an extreme anxiety response making it unsuitable for therapeutic use. Presently, there exists no universal anti-emetic drug. We tested a proprietary drug developed from DPAT, ETI-385, which successfully prevented emesis in musk shrews against chemotherapy, drug and motion stimuli. For FDA purposes, …

External Iliac Artery Stenting: High Incidence Of Concomitant Revascularization Procedures, Vance L. Smith, Laura Peterson, Jean E. Starr, Bhagwan Satiani

Department of Surgery Faculty Publications

Objectives: To review immediate results, patency rates, hemodynamic success, and incidence of concomitant procedures with external iliac artery stenting (EIAS). Methods: Demographic features, category and clinical grade, Trans-Atlantic Inter-Society Consensus II classification lesion type, pre- and postprocedure ankle–brachial indices, and primary patency were compared between group 1 (EIAS without distal revascularization) and group 2 (EIAS with concomitant distal revascularization).Results: No mortality and a 100% immediate technical success rate was recorded in group 1 (n = 12) and group 2 (n = 24). Eleven patients (30.6%) also had stenting of the adjacent common iliac artery. Two thirds …

Ohio Academy Of Medical History Annual Meeting Program, March 31, 2012, Ohio Academy Of Medical History

Annual Conference Programs

This tri-fold program is from the annual meeting of the Ohio Academy of Medical History held on March 31, 2012 at the Rose Melnick Museum of Medical History at Youngstown State University in Youngstown, Ohio. The program details the events and presentations of the meeting.

Effects Of Restricted Fructose Access On Body Weight And Blood Pressure Circadian Rhythms, Danielle Senador, Swapnil Vijay Shewale, Maria Claudia Irigoyen, Khalid M. Elased, Mariana Morris

Pharmacology and Toxicology Faculty Publications

High-fructose diet is known to produce cardiovascular and metabolic pathologies. The objective was to determine whether the timing of high fructose (10% liquid solution) intake affect the metabolic and cardiovascular outcomes. Male C57BL mice with radiotelemetric probes were divided into four groups: (1) 24 h water (control); (2) 24 h fructose (F24); (3) 12 h fructose during the light phase (F12L); (4) 12 h fructose during the dark phase (F12D). All fructose groups had higher fluid intake. Body weight was increased in mice on restricted access with no difference in total caloric intake. Fasting glycemia was higher in groups with …

Heterogeneity In Genetic Diversity Among Non-Coding Loci Fails To Fit Neutral Coalescent Models Of Population History, Jeffrey L. Peters, Trina E. Roberts, Kevin Winker, Kevin G. Mccracken

Biological Sciences Faculty Publications

Inferring aspects of the population histories of species using coalescent analyses of non-coding nuclear DNA has grown in popularity. These inferences, such as divergence, gene flow, and changes in population size, assume that genetic data reflect simple population histories and neutral evolutionary processes. However, violating model assumptions can result in a poor fit between empirical data and the models. We sampled 22 nuclear intron sequences from at least 19 different chromosomes (a genomic transect) to test for deviations from selective neutrality in the gadwall (Anas strepera), a Holarctic duck. Nucleotide diversity among these loci varied by nearly two …

'A Lion In The House' Module For Health Care Education: Pediatric End-Of-Life Case Studies, Julia Reichert, Dean Parmelee, Steve Bognar, Karen Durgans, Melissa Godoy

Medical Education Faculty Publications

Justin's Story is part of Pediatric End-of-Life Case Studies, one of seven teaching modules drawn from the Emmy Award-winning documentary, A Lion in the House. A Lion in the House portrays an unprecedented, intimate look at the realities of childhood cancer through the journeys of five families and their professional caregivers over the course of 6 years. Justin's Story provides a forum for open-ended discussion and consideration of compassionate approaches for navigating pediatric end-of-life. It offers content that is unpredictable and not always best practice. Learners reflect on the complex impact of childhood cancer on Justin, his family, and …

Differences In Immunity Offered By The Influenza Vaccination Among Active Duty Us Air Force Personnel From 2007-2011, Billy D. Pruett

Master of Public Health Program Student Publications

OBJECTIVE: To investigate the potential difference in vaccine effectiveness among Active Duty Air Force (ADAF) personnel vaccinated against influenza from 2007-2011. Particularly, to determine if any difference in the protection offered is based on sex, vaccine type, or both.

METHODS: The proposed study incorporated a cross-sectional design using the Department of Defense’s (DoD) comprehensive databases. Laboratory-confirmed influenza and other Influenza-Like Illness (ILI) cases were identified for each of the four influenza seasons of interest, vaccination status and history was then verified, and 2x2 tables were constructed in order to calculate odds ratios.

RESULTS: No consistent difference in vaccine effectiveness in …

Distribution, Population Size, And Structure Of Himalayan Grey Goral Naemorhedus Goral Bedfordi (Cetartiodactyla: Bovidae) In Pakistan, Fakhar -I- Abbas, Kathreen E. Ruckstuhl, Afsar Mian, Tanveer Akhtar, Thomas P. Rooney

Biological Sciences Faculty Publications

Himalayan grey goral (Naemorhedus goral bedfordi) is a Red List (Near Threatened) member of Caprinae endemic to Asia, occupying the south-facing slopes of the Himalaya Mountains. The species is listed as Vulnerable on the National Pakistan Red List, but the distribution and abundance of the species within the nation is poorly known. We conducted a national census of Himalayan grey goral in Pakistan during 2002 – 2004, with the objective of documenting the geographic locations of populations, estimating population size, and describing group sizes and sex ratios. We conducted a direct count census in 98 sites distributed over …

Reducing Emergency Births By Modification In Oxytocin Utilization, Gary Ventolini, Michael L. Galloway, Sheela M. Barhan, Marc R. Belcastro

Obstetrics and Gynecology Faculty Publications

Background: The purpose of our study was to explore the correlation between the amount of oxytocin use and emergency vacuum, forceps, cesarean births and neonatal intensive care unit (NICU) response to fetal distress. In 2004, we restricted the criteria for oxytocin utilization for labor induction and augmentation.

Methods: This retrospective study was carried out at a large private university tertiary care hospital- affiliated, and included data from the years 2005 to 2007. We utilized hospital data from vital statistics, labor and delivery, central pharmacy and NICU. Information obtained included maternal characteristics, annual birth data, indication and numbers of emergency vacuum, …

Time Of Day Regulates Subcellular Trafficking, Tripartite Synaptic Localization, And Polyadenylation Of The Astrocytic Fabp7 Mrna, Jason R. Gerstner, William M. Vanderheyden, Timothy Lavaute, Cara J. Westmark, Labib Rouhana, Allan I. Pack, Marvin Wickens, Charles F. Landry

Biological Sciences Faculty Publications

The astrocyte brain fatty acid binding protein (Fabp7) has previously been shown to have a coordinated diurnal regulation of mRNA and protein throughout mouse brain, and an age-dependent decline in protein expression within synaptoneurosomal fractions. Mechanisms that control time-of-day changes in expression and trafficking Fabp7 to the perisynaptic process are not known. In this study, we confirmed an enrichment of Fabp7 mRNA and protein in the astrocytic perisynaptic compartment, and observed a diurnal change in the intracellular distribution of Fabp7 mRNA in molecular layers of hippocampus. Northern blotting revealed a coordinated time-of-day-dependent oscillation for the Fabp7 mRNA poly(A) tail throughout …

The Evaluation Of Coaching As An Evidence-Based Intervention For Nurse Managers, Marie A. Bashaw

Doctor of Nursing Practice Program Projects

Nurse managers are a vital link between hospital administration, senior nursing leadership and staff nurses. Understanding and facilitating nurse managers’ job satisfaction is important for retention of current nurse managers and creating organizational success. Retaining nurse managers is not only important in terms of savings in turnover costs but for providing quality patient care. The purpose of this evidence-based practice (EBP) project was to implement a coaching intervention with nurse managers to decrease stress and improve job satisfaction.

Frameworks guiding this project were Watson’s Theory of Human Caring and Larrabee’s Model for Evidence-based Practice Change. A review of the literature …

Cardio Pulmonary Resuscitation Decisions In Nursing Home Residents, Melissa S. Bennett

Doctor of Nursing Practice Program Projects

Objective: Cardiopulmonary resuscitation (CPR) performed on nursing home residents, consistently demonstrates poor outcomes with less than 5% survival rate (AMDA, January 30, 2011). Study participants overestimate CPR survival based on television and lack of accurate information (Adams & Snedden, 2006; van Mil et al., 2000). This project evaluated use of a video decision tool on CPR choices in nursing home residents over three months.

Methods: A CPR video decision tool was added to advance care planning discussions as an audiovisual component to educate nursing home residents and their decision makers. Nurse Practitioners (NPs) documented the resident’s choices in the electronic …

Development Of A Best Evidence Statement (Best) For Confirmation Of Nasogastric (Ngt) Or Orogastric Tube (Ogt) Placement, Sherri A. Sievers

Doctor of Nursing Practice Program Projects

The purpose of this scholarly project was to develop a Best Evidence Statement (BESt) for the confirmation of nasogastric or orogastric tube placement in hospitalized children. The nose-ear-xiphoid (NEX) method of measurement and auscultatory method of tube verification is commonly used but is unreliable and has resulted in misplaced tubes as well as poor patient outcomes. Radiography is considered the gold standard however the risks outweigh the benefits due to excessive radiation exposure, increases in healthcare costs and delay in delivery of care. Methods which utilize bedside testing and proper tube measurement have been shown to be effective in nasogastric …

Rights Of Ohio Mothers: Best Practices For The Pediatric Patient With A Life-Threatening Illness, Kelly Peekstok

Master of Public Health Program Student Publications

The purpose of this paper is to evaluate and review current best practices with regards to a minor’s refusal of life-sustaining medical treatment. The policies of other developed countries and states within the United States serve as a guide for developing evidence-based guidelines for Ohio healthcare professionals. Four specific cases were identified and then analyzed. The results showed that in three of the four cases, the wishes of the minor were followed. While each case contains its own set of complexities, creating a developmental guideline for healthcare organizations will ensure protection of the minor’s capacity to make autonomous decisions.

Evidence-Based Hazmat Medical Surveillance, Michael D. Jacobson

Master of Public Health Program Student Publications

Background: Hazardous materials (HAZMAT) teams are tasked with neutralizing substances that pose a dire threat to human health. As a result, communities invest substantially in medical surveillance to protect first responders. Yet, little is known as to the actual exposures, consequent injuries, and cost-effectiveness of medical surveillance.

Objective: The purposes of this study were: 1) Determine actual HAZMAT threats. 2) In light of these threats, evaluate current regulatory requirements, recommendations and practices for their basis in evidence.

Methods: National HAZMAT data was analyzed for trends and compared with local response records from 2008 through 2011. Regulations applicable to medical surveillance …

A Descriptive Analysis Of Lung Cancer In Montgomery County, Ohio, Catherine Klose

Master of Public Health Program Student Publications

Background: Lung cancer statistics are alarming, especially when it is considered by many to largely be a preventable disease. Lung cancers are the leading cause of all cancer deaths, more than breast cancer, prostate cancer, and colon cancer combined. Cancers of the bronchus and lung make up the greatest percentage of the newly diagnosed cancers reported to the Ohio Cancer Incidence Surveillance System (OCISS). The stage of diagnosis of lung and bronchus cancers is an important determinant of survival. Smoking is the primary cause of lung cancer. Race and gender disparities also exist with lung cancer, and socioeconomic factors have …

Analyzing Healthy Lifestyle Initiatives For Seniors: A Descriptive Study Of Senior Centers In Montgomery County, Ohio, Abhinav Rajpal

Master of Public Health Program Student Publications

The population of the elderly is expected to rise due to an increase in life expectancy and the aging baby boomer population. This increase in the elderly population will likely cause a burden on the health care system. This burden can be mitigated by promoting healthy lifestyles such as increased physical activity, healthy eating, and tobacco cessation in the elderly. Additionally, by participating in healthy behaviors, seniors can significantly improve their quality of life. Senior centers are at the forefront of promoting healthy lifestyles for the elderly. By promoting physical, social, and mental well-being, senior centers act as a focal …

Analysis Of An Improved Cook Stove Intervention In Rural Guatemala, Chad Graven

Master of Public Health Program Student Publications

An estimated three billion people cook and heat their homes using open fires and nearly two million people die prematurely from illness attributable to indoor air pollution from solid fuel use. According to the World Health Organization, “every year, indoor air pollution is responsible for the death of 1.6 million people...one death every twenty seconds.” Various international groups, government initiatives, and communities have attempted to improve this indoor air pollution problem around the world by implementing various improved cook stove models. In July, 2011, Partners In Health (PIH) and Equipo Técnico de Educación en Salud Comunitaria (ETESC) co-directed the delivery …

Chronic Disease Prevalence Of A Refugee Population In Dayton, Oh, Sandeep Palakodeti

Master of Public Health Program Student Publications

Introduction: This study aimed to understand the chronic disease burden of anemia, cancer, diabetes mellitus, hypertension, overweight/obesity, stroke, and tobacco use in the domestic as well as a refugee population. It also aimed to examine the current literature on appropriate screening for those conditions.

Methods: 348 refugee screening intake exams from Public Health - Dayton & Montgomery County were analyzed for presence of the conditions stated. Screening intake recommendations from the CDC, the Minnesota Public Health Department, the Canadian Collaboration for Immigrant and Refugee Health, and the Ohio Department of Job and Family Services were examined and compared in order …

Health Enhancing Policies And Environments In Select Montgomery County Senior Centers, Stacey L. Gardner

Master of Public Health Program Student Publications

As the baby boomer generation reaches elderly status, healthcare expenditures in the United States continue to rise. Contributing to healthcare costs is the high prevalence of chronic diseases caused by unhealthy habits of Americans such as tobacco use, lack of physical activity, and consumption of a poor diet. Many chronic diseases can be prevented by engaging in healthier behaviors. Communities and organizations can shift social norms and affect behaviors through policy intervention and environmental strategies. The purpose of this study was to describe policies and environments that foster healthy lifestyles in select senior centers in Montgomery County, Ohio. Specifically, this …

Factors That Influence Food Access In The United States: A Snapshot Of Food Access In Ohio And Kentucky, Maimouna Falls

Master of Public Health Program Student Publications

Background: The United States is one the richest countries in the world with a Gross Domestic Product (GDP) per capita of $48,442, yet many communities lack access to affordable nutritious food. Access to food impacts health outcomes such as obesity and diabetes. The purpose of this study was to determine the association between food access and rates of obesity and diabetes in the states of Ohio and Kentucky.

Methods: County level food access data from 120 counties in Kentucky and 88 counties in Ohio were obtained from the USDA website. The dataset included demographic variables and poverty rates. Food access …

Tetanus Toxoid, Reduced Diphtheria Toxoid And Acellular Pertussis Vaccination And Influenza Vaccination Of Pregnant And Postpartum Women, Colleen M. Mccormick

Master of Public Health Program Student Publications

Introduction: Infants ≤2 months are at greatest risk for morbidity/mortality from pertussis. Tdap vaccines given in late pregnancy or postpartum can protect infants from pertussis. Pregnancy increases risks for maternal and perinatal complications. Influenza vaccine (FLUV) given in pregnancy can protect women and newborns.

Objectives: To determine Tdap and FLUV rates in pregnant and postpartum patients and identify factors associated with vaccination.

Methods: Miami Valley Hospital delivery records from 01/2009-12/2011 were retrospectively reviewed. Data reviewed included age, insurance, race/ethnicity, and county of residence. Descriptive statistics analyzed prevalence of immunization, timing, and demographics. Chi-square and odds ratios detected differences between characteristics. …

Review Of Civil-Military Coordination In Local Disaster Response, Wilfredo J. Nieves

Master of Public Health Program Student Publications

Background: Globally, disasters affect over 200 million people annually. Governments at all levels attempt to mitigate the effects of disasters by providing training and resources to responders in the event of a disaster. When the disaster is of sufficient magnitude, those that respond will require additional resources to adequately attend to disaster victims. County emergency managers assist in making needed additional resources available. Department of Defense (DoD) installations are sources where emergency management agency (EMA) directors may request assistance. The purpose of this research is to understand the resources legal authority available to civilian emergency managers of Ohio Counties in …

Montgomery County Prostate Cancer Study: A Descriptive Study Of Prostate Cancer Incidence & Mortality In Montgomery County, Ohio, 2000-2009, Anthony F. Greaves

Master of Public Health Program Student Publications

Background: Prostate cancer is the most common cancer diagnosed among adult males in the United States. The prognosis of prostate cancer is related to the stage, with a five year relative survival rate of 100% among men diagnosed with early stage prostate cancer. Modifiable risk factors associated with the disease include lifestyle, marital status, tobacco and alcohol history, physical activity, weight, diet, and geographic location. Non-modifiable risk factors include family history and genetic factors, race/ethnicity and nationality, age, and hormonal factors.

Methods: A descriptive study of prostate cancer primary prevention and early detection factors was conducted on men living in …

Improving Childhood Nutrition In Rural Dominican Republic, Christine L. North

Master of Public Health Program Student Publications

This nutrition education intervention seeks to decrease malnutrition and increase overall health status of rural Dominican Republic children in the village of El Cercado, Dominican Republic. Working with the Child Nutrition Program run by Solid Rock International, this educational intervention will target caregivers of children enrolled in the nutrition program. Using a multi-level strategy, this intervention focuses on hygiene practices and safe food preparation, formalized nutrition education, food access and introduction of new foods. Caregivers will take part in five interactive lesson sessions where they will engage in hands-on learning and skill development associated with the target areas. Additionally, clinic …