Medicine and Health Sciences Commons^™

Possible Involvement Of Keratinocyte-Derived Microvesicle Particles In Human Photosensitivity Disorders, Risha Annamraju, Madison S. Owens, Anita Thyagarajan, Danielle A. Corbin, Catherine M.T. Sherwin, Jade Bryant, Garrett W. Fisher, Winston R. Owens, Alycia Ketter, Craig A. Rohan, Michael G. Kemp, Robyn K. Crow, Jeffrey B. Travers

Pediatrics Faculty Publications

BACKGROUND: Previous murine studies have implicated acid sphingomyelinase-(aSMase) generated subcellular microvesicle particles (MVP) in photosensitivity. Objective: The current double-blinded placebo-controlled studies examined if a single localized ultraviolet B radiation (UVB) treatment generated more MVP in human subjects with self-identified photosensitivity versus normal controls. A topical 4% formulation of the aSMase inhibitor imipramine applied immediately after UVB blocked the MVP release and erythema responses. Erythema responses at 24 and 72 h in response to multiple UVB fluences and minimal erythema doses (MED) at 24 h and effects of imipramine were also tested.

RESULTS: Small cohorts of 10 adult self-identified photosensitive subjects …

Infection And Nonunion Rates In Open Fractures, Roman M. Natoli, Lucas S. Marchand, Sofia Bzovsky, Jennifer E. Hagen, Mark J. Gage, Christina A. Stennett, Nathan N. O’Hara, Kyle J. Jeray, Brad Petrisor, Sheila Sprague, Gerard P. Slobogean, Jeffrey Wells, Mohit Bhandari, Anthony D. Harris, C. Daniel Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Lyndsay M. O’Hara, Robert Zura, Christopher Lee, Joseph Patterson, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, The Flow Investigators, The Prep-It Investigators

Orthopaedic Surgery Faculty Publications

Background: Infection and nonunion are common sequelae of open fractures. Studies have shown infection and nonunion rates ranging from 2% to 52% and 12% to 17%, respectively. The present article describes the rates of surgical site infection (SSI) and delayed union/nonunion following open fractures in a large contemporary series of patients from prospective clinical trials with adjudicated outcomes. Methods: A descriptive analysis was performed with use of patient data from the FLOW, Aqueous-PREP, and PREPARE-Open studies. These studies, published within the past 10 years, included multiple international trauma centers and shared definitions for SSI and delayed union/nonunion. SSI and delayed …

Fascia Iliaca Compartment Block And Pericapsular Nerve Group Block Effect On Opioid Consumption In Hip Fracture Patients, David A. Brueggeman, Garrhett G. Via, Prachi Lele, Andrew W. Froehle, Michael J. Prayson, Scott J. Hadaway

Orthopaedic Surgery Faculty Publications

Background Effective pain control and reduced opioid consumption improve hip fracture outcomes. Fascia iliaca compartment blocks (FICB) effectively and safely manage acute hip fracture pain while reducing opioid consumption. Alternatively, pericapsular nerve group (PENG) blocks may provide similar analgesia while better-preserving motor function by targeting the highly innervated anterior hip capsule and sensory branches of the femoral, obturator, and accessory obturator nerves. Evidence for PENG's effectiveness is limited. The present retrospective study compared pain and MME in hip fracture patients receiving FICB (n = 1596) or PENG (n = 254), vs. a no-block (NB; n = 287) reference group. Methods …

Hawthorn (Crataegus Spp.): Unlocking Its Potential For Health And Environmental Sustainability – A Comprehensive Review, Abdelhak Maghchiche

Journal of Bioresource Management

Hawthorn (Crataegus spp.), traditionally regarded as an important medicinal plant and frequently cited in the literature, presents significant potential for sustainable development and medical biotechnology. This review looks at several areas of Hawthorn that can be explored in response to current healthcare and environmental sustainability issues. Bioactive compounds from hawthorn, including active compounds primarily comprised of flavonoids, procyanidins, and triterpenoids, are responsible for potent antioxidant, anti-inflammatory, cardio-protective, and antimicrobial activities, potentially providing a source of potent therapeutic alternatives. Moreover, hawthorn has a well-documented record as a source of cardiovascular benefits to address arterial hypertension, congestive heart failure, and arrhythmias. In …

Study On The Beneficial Effects Of Garlic, Tribulus Terrestris, And Vitamin E Supplementation On Semen Quality, Fertility, And Hatchability Of Desi Male Chicken, Iqrar Uddin Lashari, Muhammad Mohsen Rahimoon, Qudratullah Kalwar, Zafar Ali Khoso, Barkat Ali Jataoi, Majid Hussain Soomro, Hidayatullah Soomro

Journal of Bioresource Management

This study evaluated the effects of dietary supplementation with garlic, Tribulus terrestris, and vitamin E on semen quality parameters in desi male chickens maintained under local farming conditions in Sindh, Pakistan. A total of twenty-four non-descriptive desi chickens (8 males and 16 females, aged 19–20 weeks) were allocated to four dietary groups for 42 days: G1 (basal diet with 150 g/kg garlic), G2 (basal diet with Tribulus terrestris at 1 capsule/liter of water), G3 (basal diet with vitamin E at 1 capsule/liter of water), and G4 (control with basal breeding ration only). Semen samples collected from treated males were analyzed …

Effect Of Dietary Supplementation Of Symbiotic, Prebiotics And Probiotics On Conformation Of Teats In Rabbits, Saqib Kakar, Allah Bux Kachiwal, Saeed Ahmed Soomro, Akeel Ahmed Memon

Journal of Bioresource Management

This study evaluated the effects of dietary supplementation with prebiotics, probiotics, and symbiotics on the reproductive and physiological performance of New Zealand White rabbits, emphasizing teat conformation. Forty-eight rabbits were divided into four groups: control (a), prebiotics (b), probiotics (c), and symbiotics (d). During the first parity, teat conformation varied across dietary treatments, with group d (symbiotic supplementation) generally exhibiting superior teat morphology. Horizontal teat length was highest in group a (4.38±0.35) and lowest in group d (4.02±0.43). The rear teat distance from the floor was longest in group d (1.71±0.25) and shortest in group a (1.41±0.50), with a similar …

Flipping The Curriculum For Resident Didactics: In-Training And Certifying Examination Scores In An Internal Medicine Residency, Luke Mccoy, Ronald J. Markert, Elysha Thoms, Olivia Noall, Kathryn Burtson

Internal Medicine Faculty Publications

Purpose The flipped classroom (FC) model is increasingly used in undergraduate medical education, where it has been associated with improved knowledge acquisition. However, its impact on graduate medical education (GME) remains underexplored. We hypothesized that implementing a flipped didactics curriculum in our internal medicine residency program would improve performance on the Internal Medicine In-Training Examination (IM-ITE) and the American Board of Internal Medicine Certifying Examination (IM-CE). Methods In 2017, we transitioned from a traditional lecture-based (LB) curriculum to a flipped model. Noon conferences were replaced with problem-based learning (PBL) sessions three days per week, with additional active learning formats used …

Knowledge Of Hiv Transmission And Prevention Among University Students In Pakistan: A Cross-Sectional Study, Muhammad Saleem, Sajid Masood, Shahid Hussain

Journal of Bioresource Management

HIV/AIDS remains a significant public health problem internationally, with young adults being especially at risk because of behavioral and knowledge deficits. In Pakistan, cultural inhibitions and suboptimal health education are the main reasons for limited awareness, particularly among university students. This study had the objectives of determining the knowledge level about HIV transmission and prevention among undergraduate students in Kohsar University Murree (KUM) and to investigate correlations with salient demographic variables. A cross-sectional survey was carried out among 510 students aged 18-27 years through a pre-validated, standardized questionnaire with 12 knowledge-based items. Descriptive statistics and Chi-square tests were utilized to …

Dietary Organic Selenium Supplementation Improved Some Gross Morphological Parameters And Biochemical Characteristics Of Testes In Young Male Kids, Nadia Rahim, Moolchand Malhi, Asma Babar, Muhammad Awais Soomro, Shazia Rahim

Journal of Bioresource Management

Selenium (Se) plays a vital role in improving reproductive health in ruminants. This study evaluated the impact of Se supplementation on testicular health in young male goats. Twenty goats (2–3 months old, 8.5–10 kg) were randomly assigned to two groups: Control (C, n=10) receiving a basal diet (0.037 mg Se/kg) and Se-Yeast (SY, n=10) supplemented with 0.3 mg Se/kg diet. The trial lasted eight weeks. Results showed that testis weight was significantly higher in the SY group (26.8 ± 2.5 g) compared to C (22.4 ± 2.1 g, p < 0.05). Testis length, width, and circumference also increased significantly in SY goats (4.5 ± 0.3 cm, 2.9 ± 0.2 cm, and 7.4 ± 0.4 cm, respectively) compared to control (3.9 ± 0.4 cm, 2.5 ± 0.3 cm, and 6.7 ± 0.5 cm; p < 0.05). Serum cholesterol was higher in SY (135.27 ± 2.34 mg/dl) than in C (121.15 ± 8.74 mg/dl, p = 0.02), while triglycerides were lower (95.99 ± 1.37 vs. 114.38 ± 1.84 mg/dl, p = 0.0003). HDL increased (51.97 ± 2.10 vs. 45.02 ± 1.32 mg/dl, p = 0.03), and LDL decreased (54.23 ± 1.81 vs. 61.27 ± 1.56 mg/dl, p = 0.02) in SY group. Total serum protein rose significantly (8.14 ± 0.79 vs. 5.25 ± 0.06 mg/dl, p = 0.03), as did testosterone levels (1.95 ± 0.08 vs. 1.43 ± 0.06 ng/ml, p = 0.002). In conclusion, selenium supplementation significantly improved testicular morphology, lipid profile, protein levels, and testosterone, indicating enhanced reproductive health in goats.

Emerging Therapeutic Potential Of Fisetin For Nephrotoxicity, Kidney Injury, And Nephropathy: A Systematic Review, Saeed Mohajeri, Alizamen Salehifard Jouneghani, Saeid Heidari-Soureshjani, Catherine M.T. Sherwin, Faramarz Beigi

Pediatrics Faculty Publications

INTRODUCTION/OBJECTIVE: Kidney diseases cause high morbidity and mortality worldwide. This study investigated the mechanistic effects of Fisetin (FIS) on nephrotoxicity, kidney injury, and nephropathy induced by drugs, toxic chemicals, diabetes, lupus, diet, ureteral obstruction, and ischemic situations.

METHODS: To identify pertinent articles published before Oct 1, 2024, a comprehensive electronic search was performed across several databases, including MEDLINE/PubMed, Embase, Cochrane Library, Web of Science, and Scopus. After establishing clear inclusion and exclusion criteria, studies that met the research objectives were selected. Data were extracted and analyzed, documenting study characteristics, methodologies, and biological mechanisms.

RESULTS: Antioxidant benefits were evident with increased …

Addressing Pain Management Postoperatively From A Multimodal Approach In Response To The Opioid Epidemic, Victoria Pascoe

Best Integrated Writing

This review article explores the four-wave opioid epidemic across the United States and the postsurgical multimodal pain management approaches being implemented to help combat it. Breaking down the mechanistic approach to pain in the form of opioid-alternative analgesics, cryotherapeutic techniques, cognitive approaches, and more, this paper offers insight into how pain can be managed outside of the historical approach, while also exploring the future directions of the field as physicians and researchers alike search for ways to offer more comfort and quality of life to the patients who walk through their clinic doors.

Vaginismus: Causes, Diagnosis, And Treatment Options, Heather Thomas

Best Integrated Writing

This paper provides a current review of the diagnosis, causes, and treatment outcomes for vaginismus. Of particular interest are predisposing factors, like a lack of sex education and a sexually restrictive upbringing, for the development of this disorder. Controversies surrounding US-based diagnostic criteria for female sexual dysfunction are also reviewed, and up-to-date and novel treatment options, like vaginal Botox injections, are described.

Fourth Annual Research Symposium Program With Abstracts, Office Of Research Affairs, Boonshoft School Of Medicine

Boonshoft School of Medicine Research Symposium

The program booklet is a compilation of abstracts from oral and poster presentations at Wright State University's Fourth Annual Boonshoft School of Medicine Medical Research Symposium held on April 16, 2025.

Review On Treatment Outcome Of Patient With Acute Bacterial Meningitis In Pediatrics, Uswa Insaf, Faiza Waseem, Nadia Iqbal, Tehseen Riaz, Irfan Bashir, Waqas Akram

Journal of Bioresource Management

Antibiotic treatment improves outcomes of treatment, but extensively available antibiotics efficiency is vulnerable by globally appearance of development of multidrug-resistant bacteria. An infectious etiology arises, such as fungi, bacteria, viruses, mycobacteria, or parasites, or be related with cancer, autoimmunity, or medications reaction. The causative organism was recognized by most patients treated with antibiotics, culture of the CSF and blood, by countercurrent immune-electrophoresis of fluids. Neisseria meningitidis, Hemophilus influenzae b and Streptococcus pneumoniae are the commonest causes of bacterial meningitis. Bacterial meningitis has adequately extreme in the pediatrics people of developing countries. Many people with bacterial meningitis don't have any …

Psychological Influence Of Acne Vulgaris Among Female Students Of University Of Poonch Rawalakot Azad Jammu And Kashmir, Pakistan, Faryal Hanif, Ahmed Hussain, Ehsan Ali, Muhammad Rasheed

Journal of Bioresource Management

This study aimed to assess the prevalence of acne vulgaris among female students at the University of Poonch, Rawalakot, and to evaluate its impact on their quality of life using the Dermatology Life Quality Index (DLQI). A cross-sectional survey was conducted from July to August 2022, involving a total of 2000 female students. Out of these, 400 individuals were clinically diagnosed with acne vulgaris, indicating a prevalence rate of 20 %. The participants completed the DLQI questionnaire, which evaluates the psychological and social effects of dermatological conditions. The data obtained were analyzed to assess the influence of acne on various …

Study On Predisposing Factors And Control Measures Against Cryptosporidiosis In Buffalo Calves At Cattle Colony Hyderabad, Sindh, Pakistan, Ali Ul Murtaza, Abdul Latif Bhutto, Jam Kashif Zaman, Mansoor Tariq, Amjad Hussain Mirani, Riaz Ahmed Laghari, Pervez Ahmed Khoso, Muhammad Mohsen Rahimoon, Abdul Saboor, Fayaz Hussain

Journal of Bioresource Management

The current study looked at the variables affecting the frequency of Cryptosporidium Parvum in buffalo calves at the Hyderabad Cattle Colony. From calves, 100 fecal samples were taken in total, preserved, and analyzed using direct smear and Ziehl-Neelsen staining methods. 74 percent of the samples tested positive for Cryptosporidium Parvum. Disease rates were higher in Nili Ravi calves (86 %) compared to Kundhi calves (62 %), with a statistically significant difference (p

Prediction Of Lacosamide Concentrations To Support Dose Optimization During Pregnancy, Jessica M. Barry, Sílvia M. Illamola, Page B. Pennell, Catherine M.T. Sherwin, Kimford J. Meador, Angela K. Birnbaum

Pediatrics Faculty Publications

Objective: We aimed to quantify and predict lacosamide exposure during pregnancy by developing a pregnancy physiologically-based pharmacokinetic model, allowing the prediction of potential dose increases to support maintaining a patient's preconception lacosamide concentrations. Methods: Models for nonpregnant adults and pregnant female patients were constructed using physiochemical and pharmacological parameters identified from literature review. Evaluation of plasma concentration data from human males was digitized froM.T.he literature. Concentration data in nonpregnant and pregnant human females were available froM.T.he Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) study, a longitudinal observational study which followed 11 nonpregnant and 16 pregnant women receiving lacosamide. …

Pharmacokinetic Effect Of Disease Severity And Use Of Extracorporeal Membrane Oxygenation In Critically Ill Asian Patients Receiving Vancomycin, Charul Avachat, Pi Lien Hung, Angela K. Birnbaum, Daniel P. Healy, Catherine M.T. Sherwin, Alex C. Lin

Pediatrics Faculty Publications

Purpose: Vancomycin is an essential antibiotic for the treatment of severe gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA). In critically ill patients, particularly children, attaining the appropriate dosage is crucial to avert drug resistance and ensure therapeutic efficacy. This study sought to investigate the pharmacokinetics of vancomycin in critically ill Asian pediatric patients and evaluate the influence of extracorporeal membrane oxygenation (ECMO) and disease severity on vancomycin clearance. Methods: This retrospective analysis examined data from 90 critically ill Asian patients residing in Kaohsiung, Taiwan, encompassing 263 data points gathered over 2 years. A one-compartment pharmacokinetic model with first-order elimination …

Priority Competencies For Designated Education Officers In The Veterans Health Administration, Duane R. Bidwell, Anita Samuel, Ronald M. Cervero, Steven J. Durning, Sherri L. Stephan, Erin L. Patel, Marjorie A. Bowman, Holly S. Meyer

Population and Public Health Sciences Faculty Publications

Designated Education Officers (DEOs) at Veteran Health Administration (VHA) hospitals are senior educational leaders tasked with oversight of all clinical training at a particular facility. They prioritize dozens of tasks and responsibilities each day, from educational policy and strategy to staff management, financial planning, onboarding of trainees, and facility planning and management. Clarifying priority competencies for the role can help executives recruit, appoint, and evaluate capable personnel and promote effective, efficient performance. Using a federally developed method of competency analysis, researchers consulted a panel of subject-matter experts to identify priority competencies for DEOs, using data from a 2013 study that …

Use Of Ai In Family Medicine Publications: A Joint Editorial From Journal Editors, Sarina Schrager, Dean A. Seehusen, Sumi M. Sexton, Caroline Richardson, Jon Neher, Nicholas Pimlott, Marjorie A. Bowman, José E. Rodríguez, Christopher P. Morley, Li Li, James Domdera

Population and Public Health Sciences Faculty Publications

There are multiple guidelines from publishers and organizations on the use of Artificial Intelligence (AI) in publishing.1–5 However, none are specific to family medicine. Most journals have some basic AI use recommendations for authors, but more explicit direction is needed, as not all AI tools are the same.

The Wright Brothers And Their Genetic Susceptibility To Typhoid Fever, John D. Bullock, H Bradford Hawley

Population and Public Health Sciences Faculty Publications

Importance: Typhoid fever gravely sickened Orville Wright in 1896 and the disease killed his older brother, Wilbur, in 1912. The occurrence of typhoid fever among other Wright family members has never been explored.

Objective: To investigate the number of cases of typhoid fever in the Wright brothers’ family and determine if they had a predisposition to typhoid fever that might have had a genetic basis.

Methods: Biographical information concerning the Wright brothers was examined and a family tree was constructed. Using an estimated untreated case fatality rate of 20%, typhoid fever mortality data from decennial U.S. censuses (1850-1920) was converted …

Beyond The Numbers: A Qualitative Exploration Of Patient Perspectives On Postpartum Care And Maternal Mortality, Kristen A. Waters

Master of Public Health Program Student Publications

Introduction

Montgomery County faces one of Ohio's highest maternal mortality rates, with notable disparities by race. Despite their importance in reducing maternal deaths, up to 40% of women nationwide do not attend a postpartum care (PPC) visit. While well researched guidelines exist regarding the content and timing of PPC visits, there is a lack of patient perspective on this topic, specifically in the Black-identifying population in an area with a significant burden of maternal mortality.

Methods

Semi-structured interviews and focus group sessions were conducted with 31 participants of maternal health community events in Dayton, OH. Participants were asked their opinions …

Long Commute Time And Association With Physical And Mental Health Variables, Nate Hopper, Gitty Goldstein, Meytal Guller

Scholarship in Medicine - All Papers

Commuting to work or school is a common choice influenced by financial, social, or personal reasons, and it is important to ascertain whether this choice comes with negative health detriments. Using the county health data from 2016 and 2023 publicly available on the County Health Ranking and Roadmaps website, we conducted a retrospective review to see what health outcomes may be associated with a long commute. We looked at six different states, Ohio, Kentucky, Indiana, West Virginia, Pennsylvania, and Michigan. We found a very weak correlation between commute and insufficient sleep, median household income, physical inactivity, mental stress, and diabetes. …

A Quality Improvement Project To Improve Provider Awareness Of Breastfeeding Resources, Rachel St. Bernard, Allie Vela, Rose A. Maxwell, Kelly Nagy

Obstetrics and Gynecology Faculty Publications

Breastfeeding is widely acknowledged for its significant benefits for mother and child. Despite the many advantages for breastfeeding, disparities in breastfeeding rates persist, particularly among non-Hispanic Black women in Montgomery County, OH. Rates for babies born in 2020 were low for those who were ‘ever’ breastfed (NH-Black 68.8% vs white 76.6% for ‘ever’ breastfed at hospital discharge) and even lower for those who were exclusively breastfed (NH-Black 38.2% vs. NH-white 57.9% exclusively breastfed at hospital discharge).1 Ohio's breastfeeding initiation rate remains among the lowest in the nation ranking 41st out of 50 states and falling short of the Healthy People …

Investigating The Relationship Between Adult Obesity And Various Socio-Economic Factors In Ohio, Medhavi Anand, Nicholas Gural

Scholarship in Medicine - All Papers

Background: Obesity continues to be a significant concern in the United States for decades. While several advancements in the field of medicine have been established over the years, obesity has been a serious issue in the adult population in terms of its resources and cost. Objective: The aim is to direct and explore how obesity is linked to various factors such as median household income, access to exercise opportunities, excessive drinking and diabetes prevalence in the state of Ohio.
Methods: Data was collected from the County Health Rankings website from the years 2016 and 2023. Data analytics were done using …

From Stress To Social Context: Examining The Drivers Of Excessive Drinking, Esha Kulkarni, Rudra Gandhi

Scholarship in Medicine - All Papers

Investigating different variables and the impact they have on excessive drinking can help us enhance our population’s overall quality of life. Our research examined key variables, including social associations, unemployment, education level, rural residency, mental health, physical distress, and access to mental health providers.
In Ohio, excessive drinking rates increased significantly between 2016 and 2023, coinciding with a decline in social association rates. A moderate positive correlation was identified between excessive drinking and educational attainment (r = .480, p < .001), suggesting increased alcohol use in more educated populations. Unexpectedly, a weak negative correlation emerged between unemployment and excessive drinking, challenging conventional assumptions. Additionally, the prevalence of frequent poor mental health in Ohio rose remarkably between 2016 and 2023, underscoring the growing burden of mental health challenges. Interestingly, no significant correlations were found between excessive drinking and rural residency or the availability of mental health providers. Lastly, a significant 37% of the variance in excessive drinking was explained by frequent physical distress, highlighting alcohol's potential role as a coping mechanism.
These results underscore the multifaceted nature of excessive drinking and its ties to societal and individual stressors. Addressing these issues through …

An Investigation Into The Use Of Rates Of Uninsurance As A Marker For Community Health In The State Of Ohio, Ashni Patel, Bayley Mcritchie

Scholarship in Medicine - All Papers

Objective: Previous studies have shown a correlation between rates of uninsurance and worse health outcomes. However, the efficacy of utilizing uninsurance rates as a marker for community health has not been clearly shown. Therefore, this study investigates how rates of uninsurance in Ohio correlate with worse health outcomes, as well as how Ohio counties utilize health insurance.
Methods: County Health Rankings was used look at rates of uninsurance among adults and children in Ohio along with diabetes prevalence, preventable hospitalizations, and premature death. T-tests, ANOVA, and Pearson and Spearman correlations were utilized to determine the effects of uninsurance rates on …

Residential Segregation And Mental Health Outcomes In Ohio In 2023, Wasequddin Mohammed, Hannah Qin

Scholarship in Medicine - All Papers

Background: This paper explores causational and correlational relationships between residential segregation and mental health outcomes for 88 counties within Ohio. Alongside mental health outcomes, additional variables evaluated include access to mental health and primary care.
Objective: To determine relationships between residential segregation index and mental health outcomes in Ohio between 2016-2023.
Methods: Data will be obtained from County Health Rankings and Roadmap. Inclusion criteria specify counties within Ohio with data obtained from 2016 and 2023. All data points provided within the selected variables located in County Health Rankings and Roadmap will be included. Variables included are residential segregation, mental health …

Examining The Relationship Between Teen Pregnancy And Educational Outcomes In Ohio, Andrea Szep, Maryyam Durrani

Scholarship in Medicine - All Papers

Objective: The aim of this study is to explore the relationship between educational outcomes,school funding, and teen birth rates in Ohio counties between 2020 and 2024. Methods: Usingdata from County Health Rankings, we performed regression, correlation, and paired t-testanalyses through the SPSS software. Results: The results of our tests showed significantnegative correlations between markers of educational success, including high school graduationrates math and reading standardized test scores, and teen birth rates in both 2020 and 2024.Between 2020 and 2024, the teen birth rate decreased in the state of Ohio, and in 2024, publicschool funding was able to predict 14.8% of …

Comparison Of Four Vaginal Antiseptic Preparation To Reduce Bacteria Colony Counts In Patients Undergoing Vaginal Surgery: A Randomized Trial, James R. Saelens, Adam J. Langer, Andrew N. Boeckley, Natalie M. Castillo, Julie A. Desouza, Jennifer L. Drerup, Kelly M. Muterspaw, Hannah M. Stump, Rose A. Maxwell, Geoffrey D. Towers

Obstetrics and Gynecology Faculty Publications

Introduction: Surgical site infections (SSI) remain a prominent complication of gynecologic procedures. The only FDA approved compound for preoperative vaginal preparation is povidone-iodine. Direct comparison of commonly used agents is needed to inform appropriate standards of care. The objective of this study is to compare the effectiveness of 10% povidone-iodine (PI), 4% chlorhexidine gluconate (CHG), baby shampoo (BS), and 3% para-chloro-meta-xylenol (PCMX) preparations for reducing bacterial and fungal colony counts and minimizing postoperative irritation after vaginal surgery. Materials and Methods: This is a single-blind, RCT conducted between 2018 and 2023 in patients 18 years or older who were undergoing surgeries …