Medicine and Health Sciences Commons^™

Walkability At Wright State University, Lan H. Nguyen

Master of Public Health Program Student Publications

The purpose of this study was to examine walkability at Wright State University (WSU), Dayton Ohio using the Postsecondary Education Campus Walkability/Bikeability Semantic-Differential Assessment Instrument. Safety, path quality, and path temperature comfort were the categories of criteria assessed. A total of 66 path segments were assessed on main campus, 50 were assessed during the day and 16 were assessed during the night. The average walkability score was 84.9% for day assessed segments and 82.1% for night assessed segments. Path segments received an overall average grade of B. The findings in this study suggest that the WSU campus is a walkable …

Flight Physician - January, 2012, Civil Aviation Medical Association

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A sixteen page newsletter of the Civil Aviation Medical Association. The newsletter provided news about civil aviation medicine and information related to the organization.

Best Practice For Casualty Simulation - Role-Playing Actor, High Fidelity Mannequin Simulation, Or Virtual Reality?, Robert Sarlay

Master of Public Health Program Student Publications

Objective: The purpose of this systemic review of the literature is to determine the best practice with regards to simulating casualties during a disaster response exercise.

Methods: MEDLINE was searched from 1950 till present for the key terms of disaster, simulation, and emergency preparedness. Articles were included which met the following criteria: English language, human subjects, original research using any research design (with or without intervention), and primary focus of disaster preparedness using simulation, virtual reality, or role playing actors.

Results: Of the 386 articles reviewed only 18 met inclusion criteria. The literature is primarily descriptive in nature with regards …

Needs Assessment For The Mobile Health Clinic Of The Sukhdev Raj Soin Hospital, Luke Rothermel

Master of Public Health Program Student Publications

India has an established system of medical and public health services to provide care to all citizens through a government‐run network of providers and infrastructure. That system, though, is constrained by socio‐economic limitations, a booming population, and the cultural variations of its population. In addition to the public efforts to provide health care, the private sector has grown to serve a large portion of the population. Many of these private initiatives are found in urban areas where the potential for financial gain are great, but others have spread into semi‐urban areas and villages to serve the more rural populations. The …

Pregnancy Management Strategies And Childbirth Experiences Of Internally Displaced Women In Barranquilla, Colombia, Bre Bolivar

Master of Public Health Program Student Publications

This ethnographic study aims to illuminate the experiences of pregnant and new mothers in poor areas of Colombia with respect to pregnancy and childbirth. Ethnographic observations including key informant qualitative interviews were performed by the primary investigator in four different neighborhoods in and around the city of Barranquilla, Colombia, over the course of 3 months. A total of 24 women were interviewed, and additional interviews were held with Colombian medical students, religious workers and not-for-profit healthcare leaders. I seek to better understand the perspectives of these internally displaced women in terms of contraception use including the sense of necessity of …

Influence Of The Patient Protection And Affordable Care Act On The Development Of The Patient Centered Medical Home, Anjali Rao

Master of Public Health Program Student Publications

The Patient Centered Medical Home (PCMH) model of care incorporates many public health concepts. Some supporters of PCMH regard the Affordable Care Act (ACA) as legislation that will invigorate PCMH progress across the country. This policy analysis intends to understand the influence of the ACA on the development of PCMH. The policy analysis compares relevant sections of the ACA with core PCMH concepts agreed upon by major medical professional organizations. The evaluative framework uses a “traffic light” system to rate each section of the ACA based on the accuracy of the section as compared to PCMH criteria, and denotes whether …

The Efficacy Of Abstinence Only Education, Jennie Watt Mcadams

Master of Public Health Program Student Publications

Chlamydia, Gonorrhea and unplanned teen pregnancies cost the United States billions of dollars every year in various forms of government aid. Why are the numbers of teenage incidences of these health indicators higher than almost every other industrialized nation? Why are the youth in the United States so far behind their peers in sexual health? This paper proposes that one cause is that government funding goes to abstinence only education curriculum which is taught in many schools across the nation. These curricula many times do not teach youth about sexual protection or health and other times contain false information. If …

Correlation Of Discharge Diagnostic Codes With Laboratory-Confirmed Methicillin-Resistant Staphylococcus Aureus Bloodstream Infections At A Large Pediatric Hospital, Andrew J. Kreppel

Master of Public Health Program Student Publications

Background: Methicillin-resistant Staphylococcus aureus (MRSA)-specific hospital discharge codes were introduced in October 2008. The purpose of this project is to study the correlation of these codes with laboratory-proven pediatric MRSA bloodstream infections.

Methods: Laboratory and discharge databases were used to identify patientsChildren’s Hospital Medical Center from October 2008 through December 2010 with MRSA bloodstream infections. The laboratory database identified patients with a positive blood culture for MRSA, and the discharge database identified patients with an MRSA bloodstream discharge code (038.12 for MRSA sepsis or 041.12 for MRSA infection with either 790.7 for bacteremia or 771.81 for newborn sepsis or 771.83 …

State Policies For Health Education In Public Schools, Lynda K. Vu

Master of Public Health Program Student Publications

Background: Federal and state governmental activities have significantly influenced schools’ health education practices over the past 50 years. Evaluation of these initiatives in the scientific literature has enhanced development of health education and influenced the creation of the National Health Education Standards (NHES). The Centers for Disease Control and Prevention (CDC) conducts periodic surveys to evaluate the impact of state and local policies on school health education programs and practices.

Objectives: This research project reviews and analyzes state health education policies for the 50 states plus the District of Columbia with regard to the recommendations of the NHES. It also …

Trends In Maternal And Infant Health: An Analysis Of Births In Montgomery County, Ohio, 2000-2010, Abby Burns

Master of Public Health Program Student Publications

The demographic characteristics of women who give birth are continually changing. Age, education, use of assisted reproductive technology, BMI before pregnancy, and weight gain during pregnancy are maternal factors that play a role in maternal and fetal health. Other factors including induction, route of delivery, calculated gestational age, and birthweight help determine and identify complications of pregnancy. The purpose of this study is to analyze trends of maternal demographics, risk factors, and birth outcomes associated with poor health outcomes. This research is a secondary analysis of Ohio Natality Statistical Files collected by the Ohio Department of Health, Center for Vital …

Understanding Underinsurance In Ohio, Meaghan Ebetino

Master of Public Health Program Student Publications

Objectives: To determine the prevalence, predictors, and consequences of underinsurance in the state of Ohio.

Study Design: The investigators created the dependent variables Underinsured, Financial Stress, and Harder to get Health Care using the 2008 Ohio Family Health Survey (OFHS). The sample used for this study included 29,778 respondents, who were adults less than 65 years old and who were continuously insured for the past 12 months.

Results: The study categorized twenty-two percent of the sample respondents as underinsured because they were not able to obtain or delayed needed medical care because of an inability to pay in …

Implementation Of The Sbar Checklist To Improve Patient Safety In The United States Air Force Aeromedical Evacuation, Karey M. Dufour

Nursing and Health Masters Publications

Inadequate or absent communication resulting in patient safety is an increasing problem in United States Air Force (USAF) aeromedical evacuation (AE). In 2010, 1,694 incident reports were filed. The lack of handoff communication was the second highest category affecting patient safety. Currently, there is no standardized patient handoff process in USAF AE. This evidence-based practice project is designed to answer the following question: In AF flight nurses transporting patients in the AE system, does the use of a standardized patient handoff checklist (using SBAR [situation-background-assessment-recommendation/request]), compared to current patient handoff practices, affect patient safety as measured by incident reports over …

A Guide To Acquiring Healthy Nutrition And Fitness Habits For College Students: Preventing Diabetes, Hypertension, Coronary Heart Disease, And Stroke, Darin P. Dillinger

Master of Humanities Capstone Projects

For the past three decades, obesity has been cited as a growing epidemic in the United States, according to the New England Journal of Medicine (NEJM). Obesity is a major contributing problem to a number of medical conditions. Studies in the NEJM have “correlated obesity with myriad cancers, coronary heart disease, hypertension, diabetes, and stroke,” and other health-related problems (Fumento). Healthcare experts, doctors, and practitioners estimate it will cost billions of dollars a year to bring this problem under control and it is a major contributing factor in the rising cost of healthcare (Oliver 1). Luppold, Violette, and other practitioners …

Rose Melnick Medical Museum: Past, Present, And Future, Cassie Nespor

Annual Conference Presentations, Papers, and Posters

Dr. John C. Melnick was interested in local medical history; as a result, he began collecting medical artifacts in 1972. He wanted to create a museum that would cultivate an interest in medicine and promote medical history. His collection of artifacts came to Youngstown State University in 1997, and the museum opened in 2001

Correlation Of Air Displacement Plethysmography With Alternative Body Fat Measurement Techniques In Men And Women, Brittany L. Reinert, Roberta L. Pohlman, Lynn K. Hartzler

Biological Sciences Faculty Publications

Obesity has reached epidemic proportions with serious health consequences. Techniques used to measure body fat (BF) yield variable BF estimates, and this variability may lead to underestimation or overestimation of BF and subsequent treatment options. The measurements that are most accurate (Dual-Energy X-ray Absorptiometry (DEXA) and Air Displacement Plethysmography (ADP)) are expensive and often unavailable. The purpose of this study is to find the commonly available BF measurement that is the most accurate and practical for individual body types in the general population and compare these measurements to ADP (BOD POD^®) as the standard. Field measurements include skinfolds …

Prmt5 And The Role Of Symmetrical Dimethylarginine In Chromatoid Bodies Of Planarian Stem Cells, Labib Rouhana, Ana P. Vieira, Rachel H. Roberts-Galbraith, Phillip A. Newmark

Biological Sciences Faculty Publications

Planarian flatworms contain a population of adult stem cells (neoblasts) that proliferate and generate cells of all tissues during growth, regeneration and tissue homeostasis. A characteristic feature of neoblasts is the presence of chromatoid bodies, large cytoplasmic ribonucleoprotein (RNP) granules morphologically similar to structures present in the germline of many organisms. This study aims to reveal the function, and identify additional components, of planarian chromatoid bodies. We uncover the presence of symmetrical dimethylarginine (sDMA) on chromatoid body components and identify the ortholog of protein arginine methyltransferase PRMT5 as the enzyme responsible for sDMA modification in these proteins. RNA interference-mediated depletion …

Morphological Variation Of Rusty Crayfish Orconectes Rusticus (Cambaridae) With Gender And Local Scale Spatial Gradients, Luke Etchison, Stephen J. Jacquemin, Michael Allen, Mark Pyron

Biological Sciences Faculty Publications

We tested for the influence of gender, stream, and urbanization on morphological variation in rusty crayfish (Orconectes rusticus) in an east-central Indiana, US watershed. We used geometric morphometrics to characterize shape and tested for differences among and within sites. Males had shallower rostrum, increased head width and length, decreased abdomen and cephalothorax width and length, and increased telson length compared to females. Morphology of males did not vary with stream or along an urban gradient. The morphology of females varied with stream and along an urban gradient. Female shapes from small creek sites were stouter and less fusiform …

Loss Of Renal Allografts Secondary To Candida Vascular Complications In Two Recipients From The Same Donor, Govardhana R. Yannam, Lucile E. Wrenshall, R. Brian Stevens

Neuroscience, Cell Biology & Physiology Faculty Publications

Infections remain a major cause of morbidity and mortality in transplant patients. Organ recipients are also susceptible to donor-derived pathogens and the majority of donor infections are easily treatable. Rarely, some pathogens have produced life-threatening complications by compromising the vascular anastomosis. In this case series we report loss of two kidney allografts secondary to vascular complications due to Candida albicans. Both recipients received grafts from a common donor, in whom Candida bacteremia in the donor was not apparent at the time of organ acceptance but became apparent on delayed cultures.

Intracranial Pressure Is A Better Predictor Of Mortalitythan Cerebral Perfusion Pressure, Ronald J. Markert, Jonathan M. Saxe, Cathryn L. Chadwick

Internal Medicine Faculty Publications

Objective: To evaluate whether elevated intracranial pressure (ICP) or depressed cerebral perfusion pressure (CPP) is a better predictor of intracranial compartment syndrome and long-term functional outcomes in blunt traumatic brain injury.

Methods: This was a retrospective evaluation of data collected on 203 patients with blunt traumatic brain injury who were admitted to Miami Valley Hospital, a Level I trauma center, over a 2 years period, whose initial hospital management required an intracranial pressure monitor. Serial measurements of ICP and CPP were recorded during the patients’ hospital stay. These patients were then evaluated at 3,6,12 and 24 months post-injury to assess …

The Role Of Corticotropin-Releasing Factor In The Behavior And Proinflammatory Activity Of Separated Guinea Pig Pups, Vincent Rasahd Alexander

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Isolation of guinea pig pups in a novel environment first produces active behaviors such as vocalizing and movement; over time, these behaviors wane and pups show characteristic passive responses similar to those produced by increased proinflammatory activity. Further, isolation of pups on two consecutive days has recently been shown to enhance those passive responses on the second day. Endogenous proinflammatory activity is thought to mediate the enhancement (sensitization). An injection of corticotropin-releasing factor (CRF) has been shown to increase passive behavior, possibly by increasing proinflammatory activity. The present study further investigated the role of CRF on proinflammatory activity and behavior …

Electrophysiological Abnormalities In Sod1 Transgenic Models In Amyotrophic Lateral Sclerosis: The Commonalities And Differences, Sherif M. Elbasiouny, Katharina Quinlan, Tahra L. Eissa, Charles J. Heckman

Neuroscience, Cell Biology & Physiology Faculty Publications

Since its first description in 1874 by Charcot, the hallmark feature of ALS is the progressive degeneration of upper and lower motoneurons (Charcot, 1874). In the spinal cord, motoneuron degeneration starts long before symptom onset and advances in a size-related fashion, in which large-size alpha-motoneurons degenerate first followed by small-size alpha-motoneurons (Pun et al., 2006; Hegedus et al., 2007; Hegedus et al., 2008). There are conflicting reports regarding the survival of the smallest-sized spinal motoneurons, the gamma-motoneurons (Swash and Fox, 1974; Sobue et al., 1981). Despite its original description, the neuronal degeneration in ALS is not limited to motoneurons. Recent …

Electronic Nose Based On Independent Component Analysis Combined With Partial Least Squares And Artificial Neural Networks For Wine Prediction, Teodoro Aguilera, Jesús Lozano, José A. Paredes, Francisco J. Alvarez, José I. Suárez

Neuroscience, Cell Biology & Physiology Faculty Publications

The aim of this work is to propose an alternative way for wine classification and prediction based on an electronic nose (e-nose) combined with Independent Component Analysis (ICA) as a dimensionality reduction technique, Partial Least Squares (PLS) to predict sensorial descriptors and Artificial Neural Networks (ANNs) for classification purpose. A total of 26 wines from different regions, varieties and elaboration processes have been analyzed with an e-nose and tasted by a sensory panel. Successful results have been obtained in most cases for prediction and classification.

Maturation Of The Carotid Body Oxygen-Sensor During Rat Development, Julia Paulet

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Carotid bodies (CB) are paired, oxygen-sensing organs located in the bifurcation of the carotid artery that act as peripheral chemoreceptors in the detection of hypoxic, hypercapnic and acidotic levels in the arterial blood. CBs respond to these fluctuations in blood gases by initiating firing of the carotid sinus nerve. This ultimately results in the appropriate ventilatory change to restore blood gases to their physiological levels. Studies have shown that the hypoxic response of the carotid body in juvenile mammals is low, but as maturation occurs this response is strengthened and clearly exhibited in adults. One theory suggests mitochondria play a …

Effects Of Elevated Glucocorticoid Levels On Dentate Gyrus Development, Zachary Dale Vallandingham

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Exogenous glucocorticoids are commonly used in modern medications and animal studies examining the effects of glucocorticoids on the developing brain report inconsistent results. Recent reports have questioned the reliability of available drug delivery methods in mice (Herrmann et al., 2009). In our laboratory, variable behavioral results using trace eyeblink conditioning (EBC) suggest that we may be having similar problems delivering glucoroticoids to developing rat pups (Claflin et al., 2005, 2011). Subcutaneous pellets and osmotic minipumps resulted in impaired learning during trace eyeblink conditioning whereas subcutaneous injection of corticosterone (CORT) resulted in facilitation of learning on the same task. One of …

Electrical Brain Stimulation And Depressive-Like Behavior In Guinea Pigs, Nadia Kardegar

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Maternal separation in guinea pigs produces a biphasic response consisting of an active behavior phase (vocalizations and locomotor activity) followed by a phase of passive depressive-like behavior (crouched stance, piloerection, and eye closure). The mechanism for the transition from the active to the passive phase is unknown. One suggestion is that continual activity of neural circuitry producing active behavior eventually leads to the expression of passive behaviors. The purpose of this study was to test this possibility. Guinea pigs were assigned to experimental and control groups. The experimental group received daily stimulation of the bed nucleus stria terminalis (BNST) to …

Glutamate Receptor-Mediated Taurine Release From The Hippocampus During Oxidative Stress, Brian Christopher Tucker

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Oxidative stress is an important result of cerebral ischemia and has been directly linked to hippocampal swelling and cytotoxic brain edema in vitro. Swollen brain cells activate volume regulatory mechanisms including a significant efflux of the endogenous sulfonic amino acid taurine via volume-regulated anion channels (VRACs). Studies in brain slice preparations also suggest that the excitatory amino acid glutamate plays an important role in both brain tissue swelling and in cell volume regulation. We examined relationships between oxidative stress, glutamate receptor activation, cell swelling, and volume regulation in acutely prepared slices of rat hippocampus. Our results indicate that the release …

Influence Of Daily Electrical Stimulation Of Periaqueductal Grey On Vocalization And Depressive-Like Behavior During Separation In Guinea Pigs, Jennifer Dazey

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Maternal separation has been shown to promote the onset of depression. This early life stressor produces a biphasic response marked by an active "protest" phase followed by a passive "despair" phase in humans as well as several other species. In infant guinea pigs, active phase behaviors include increased locomotion and species-typical distress vocalizations, whereas the passive phase is marked by depressive-like behaviors including a crouched stance, eye-closure and extensive piloerection. The mechanism underlying the transition from one phase to the next is still unknown. The purpose of this study was to determine if daily stimulation of the neural pathway initiating …