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Veterinary Medicine

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Articles 5041 - 5070 of 9767

Full-Text Articles in Medicine and Health Sciences

Seasonal Monitoring Of Dengue Infection In Aedes Aegypti And Serological Feature Of Patients With Suspected Dengue In 4 Central Provinces Of Thailand, Jakkrawarn Chompoosri, Usavadee Thavara, Apiwat Tawatsin, Surapee Anantapreecha, Padet Siriyasatien Jul 2012

Seasonal Monitoring Of Dengue Infection In Aedes Aegypti And Serological Feature Of Patients With Suspected Dengue In 4 Central Provinces Of Thailand, Jakkrawarn Chompoosri, Usavadee Thavara, Apiwat Tawatsin, Surapee Anantapreecha, Padet Siriyasatien

The Thai Journal of Veterinary Medicine

This study aimed to determine seasonal dengue infection rates in Ae. aegypti mosquitoes and dengueinfection in suspected patients in 4 central provinces of Thailand. Ae. aegypti mosquitoes collected during threeseasons and blood specimens taken from patients with suspected dengue were detected and serotyped for dengueviruses using RT-PCR. The biting behavior of Ae. aegypti females was studied by 24-hour mosquitoes collection once amonth using human bait for determination of seasonal biting rate. Dengue infection rates in Ae. aegypti femalesobtained from all the 4 provinces were highest in hot season and varied from place to place ranging from 64.4% to77.5%, whereas morbidity …

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Cloning And Prokaryotic Expression Of Cdnas From Hepatitis E Virus Structural Gene Of The Sw189 Strain, Bao-Cheng Hao, Xi Lan, Xiao-Yong Xing, Hai-Tao Xiang, Feng-Qin Wen, Yu-Yao Hu, Yong-Hao Hu, Jian-Ping Liang, Ji-Xing Liu Jul 2012

Cloning And Prokaryotic Expression Of Cdnas From Hepatitis E Virus Structural Gene Of The Sw189 Strain, Bao-Cheng Hao, Xi Lan, Xiao-Yong Xing, Hai-Tao Xiang, Feng-Qin Wen, Yu-Yao Hu, Yong-Hao Hu, Jian-Ping Liang, Ji-Xing Liu

The Thai Journal of Veterinary Medicine

It is necessary to study the second open reading frame (open reading frame 2, ORF2) and antigenic peptidescharacteristic of genotype 4 of HEV, and create one kind of high sensitivity and specificity of anti-HEV IgM detectionkit. The objective of this study was to obtain recombinant antigen for development of anti-HEV ELISA method andvaccine against hepatitis E virus infection. A 728 base cDNA was collected from 5'-terminus of open reading frame 2(ORF2) among epidemic hepatitis E virus (HEV) isolated from Gansu, Western China. The fragment was digestedwith Not I and Nco I, and inserted into vector pET32a(+). The recombinant plasmid was …

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Acute And Subchronic Toxicity Study Of Ardisia Ellipica Thunb. Fruit Extract, Nalinphat Saktiyasunthorn, Songpol Chivapat, Pornchai Sincharoenpokai, Anudep Rungsipipat, Nongnuth Maneechai, Boonyanee Suphaphon, Aussavashai Shuayprom Jul 2012

Acute And Subchronic Toxicity Study Of Ardisia Ellipica Thunb. Fruit Extract, Nalinphat Saktiyasunthorn, Songpol Chivapat, Pornchai Sincharoenpokai, Anudep Rungsipipat, Nongnuth Maneechai, Boonyanee Suphaphon, Aussavashai Shuayprom

The Thai Journal of Veterinary Medicine

Several plants species in the genus Ardisia contained various biologically active compounds. Ram Yai orPilangkasa (Ardisia elliptica Thunb.) has been used in traditional medicines. The objective of this study was to evaluatethe safety of ethanolic extract of A. elliptica fruit in animal models by oral administration. Acute toxicity test in miceby gavage the extract at each dose of 2.5 g/kg twice revealed no abnormal signs, mortality and gross lesion of vitalorgans. Subchronic toxicity study was investigated in one hundred Wistar rats separated into five groups, each oftwenty (ten males and ten females). Two control groups received distilled water and 0.5% …

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Ecg Quiz, Chollada Buranakarl, Kittipong Tachampa Jul 2012

Ecg Quiz, Chollada Buranakarl, Kittipong Tachampa

The Thai Journal of Veterinary Medicine

No abstract provided.

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Neospora Caninum And Toxoplasma Gondii Antibodies In Captive Elephants (Elephaus Maximus Indicus) In Kanchanaburi Province, Jitbanjong Wiengcharoen, Weerapan Nokkaew, Samart Prasithpon, Pornsak Prasomtong, Yaowalark Sukthana Jul 2012

Neospora Caninum And Toxoplasma Gondii Antibodies In Captive Elephants (Elephaus Maximus Indicus) In Kanchanaburi Province, Jitbanjong Wiengcharoen, Weerapan Nokkaew, Samart Prasithpon, Pornsak Prasomtong, Yaowalark Sukthana

The Thai Journal of Veterinary Medicine

Although neosporosis has long been detected in several wildlife species from different parts of the world,until now there has been no report of Neospora caninum infection in elephants in any country of the world. Serumsamples of 115 captive elephant (Elephas maximus indicus) from the westernmost province of Kanchanaburi, Thailandwere investigated for antibodies to N. caninum and Toxoplasma gondii. Antibodies of N. caninum were detected by thecompetitive ELISA (cELISA) test and T.gondii by the Latex agglutination (LAT) test. The prevalence of T. gondiiantibodies was 13.04% (15/115), while anti-N. caninum was 33.04% (38/115). Only 7/115 (6.09%) were positive forboth parasites. Our study …

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A Century And A Half Of Research On The Stable Fly, Stomoxys Calcitrans (L.) (Diptera: Muscidae), 1862-2011: An Annotated Bibliography, K. M. Kneeland, Steven R. Skoda, Jerome A. Hogsette, A. Y. Li, Jaime Molina-Ochoa, Kimberly Hutchinson Lohmeyer, John E. Foster Jul 2012

A Century And A Half Of Research On The Stable Fly, Stomoxys Calcitrans (L.) (Diptera: Muscidae), 1862-2011: An Annotated Bibliography, K. M. Kneeland, Steven R. Skoda, Jerome A. Hogsette, A. Y. Li, Jaime Molina-Ochoa, Kimberly Hutchinson Lohmeyer, John E. Foster

Department of Entomology: Faculty Publications

The stable fly, Stomoxys calcitrans, is a cosmopolitan pest of livestock, wild animals, pets, and humans. It is a primary pest of cattle in the United States, estimated to cause more than $1 billion in economic losses annually. It also causes dissension at the rural-urban interface and is a problem in recreation areas such as Florida beaches and the Great Lakes. Due to its pestiferous nature and painful bite, methods to control stable flies have been investigated for over a century. A large amount of research has been reported on stable fly biology, ecology, genetics, physiology, and vector competence. …

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Role Of Matrix Metalloproteinases In Animals, Sariya Asawakarn, Tanong Asawakarn Jul 2012

Role Of Matrix Metalloproteinases In Animals, Sariya Asawakarn, Tanong Asawakarn

The Thai Journal of Veterinary Medicine

Matrix metalloproteinases are a family of calcium-dependent and zinc-dependent endopeptidases, which excrete from many cell types. These enzymes can hydrolyze extracellular matrix proteins. The most important inhibitor of MMPs is tissue inhibitors of metalloproteinases (TIMPs). The imbalance between MMPs and TIMPs causes pathological condition in human and animals. This review focuses on structural, role and several reports of MMPs in horse, dog, cat, fish and avian. Over production of MMPs is associated with tissue destruction and erosion of cartilage in equine osteoarthritis, especially MMP-2 and MMP-9. In canine and feline, many evidences reported about MMPs and cancer such as MMP-2 …

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Risk Factors Of Subclinical Mastitis In Small Holder Dairy Cows In Khon Kaen Province, Chaiwat Jarassaeng, Suneerat Aiumlamai, Chalong Wachirapakorn, Mongkol Techakumphu, Jos P.T.M. Noordhuizen, Anton C. Beynen, Siriwat Suadsong Jul 2012

Risk Factors Of Subclinical Mastitis In Small Holder Dairy Cows In Khon Kaen Province, Chaiwat Jarassaeng, Suneerat Aiumlamai, Chalong Wachirapakorn, Mongkol Techakumphu, Jos P.T.M. Noordhuizen, Anton C. Beynen, Siriwat Suadsong

The Thai Journal of Veterinary Medicine

This cross-sectional study was introduced to determine the risk factors of subclinical mastitis in dairy farms. Sixteen small holder farms and 285 milking cows in Khon Kaen province were selected for the study. The mastitis investigation, feeding information and clinical inspection were applied in the farm visits. Milk samples from each quarter with a CMT score of 3 and bulk milk were collected for bacterial identification and somatic cell counts. The prevalence of subclinical mastitis and associated factors were analyzed. Results found that the prevalence of subclinical mastitis was 36.14%. Major microorganisms isolated from infected quarters were Streptococcus spp. and …

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Early Selection According To Repeatability Of Body Measurements Of Turkish Arabian Foals, Süleyman Çilek Jul 2012

Early Selection According To Repeatability Of Body Measurements Of Turkish Arabian Foals, Süleyman Çilek

The Thai Journal of Veterinary Medicine

In this study, body measurements of Turkish Arabian foals at different ages was obtained from Anadolustate farm in Turkey which included body length, cannon bone circumference, heart girth and withers heightmeasurements. Effects of sex, birth month, birth year and age of foal at different growth periods on withers height,body length, heart girth and cannon bone circumference were significant (p<0.05). Effects of environmental factors onall body measurements were standardized additively. Using intra-class correlation method, repeatability was 0.55 forwither height, 0.47 for heart girth, 0.26 for cannon bone circumference for forelimb and 0.31 for body length.According to moderate level results of repeatability for especially heart girth and wither height measurements,selection of Turkish Arabian foals may be conducted at an early age according to body measurements at 6 months ofage.

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Genetic Associations Between Stillbirth, Total Number Of Piglets Born And Gestation Length In A Commercial Pig Farm, Nalinee Imboonta, Prapatsara Kuhaaudomlarp Jul 2012

Genetic Associations Between Stillbirth, Total Number Of Piglets Born And Gestation Length In A Commercial Pig Farm, Nalinee Imboonta, Prapatsara Kuhaaudomlarp

The Thai Journal of Veterinary Medicine

Data of purebred Landrace, Large White and their crossbreds taken from a commercial swine farm locatedin the north-eastern part of Thailand were used to evaluate the genetic associations of stillbirth with the total numberof piglets born and gestation length. The analyses were base on 28,275 litters born from 2002 to 2006. Analysis wascarried out with a multivariate animal model using average information REML procedures. Heritability estimates forstillbirth, the total number of piglets born and gestation length were 0.03±0.01, 0.03±0.01 and 0.16±0.01, respectively.The genetic correlation between the total number of piglets born and stillbirth was positive. The genetic correlationbetween the total …

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A Comparative Study On The Efficacy Of Four Semen Extenders And Thawing By Seminal Plasma On The Quality Of Frozenthawed Boar Semen, Chonthida Rienprayoon, Chonlapat Klangnak, Suttiporn Onton, Chanyuth Tretipskul, Padet Tummaruk Jul 2012

A Comparative Study On The Efficacy Of Four Semen Extenders And Thawing By Seminal Plasma On The Quality Of Frozenthawed Boar Semen, Chonthida Rienprayoon, Chonlapat Klangnak, Suttiporn Onton, Chanyuth Tretipskul, Padet Tummaruk

The Thai Journal of Veterinary Medicine

The present study investigated the influence of four different commercial semen extenders used during theholding time and the use of seminal plasma as a thawing medium on the frozen-thawed (FT) boar semen quality.Sperm-rich fractions were collected from 11 boars and were divided into four groups according to the type of semenextender used during the holding time (A, B, C and D). The extended semen was cooled down and centrifuged. Thesperm pellets were diluted in lactose-egg yolk extender plus glycerol and Equex STM Paste. The semen were loadedinto 0.5 ml straws and frozen. Thawing was achieved by immersing the straws in …

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The Depletion Of Intracellular Glutamine By Methionine Sulfoximine On Amino Acid Uptake In Placental Cells (Bewo), Boonrit Thongsong Jul 2012

The Depletion Of Intracellular Glutamine By Methionine Sulfoximine On Amino Acid Uptake In Placental Cells (Bewo), Boonrit Thongsong

The Thai Journal of Veterinary Medicine

The intracellular concentration of glutamine is very high where it plays a central role as a ready source ofnitrogen, carbon and energy in various metabolic processes. The purpose of the present study was to investigate theinfluence of intracellular glutamine status on amino acid uptake activity in placental choriocarcinoma (BeWo) cells,analogous to normal placental trophoblasts. Intracellular glutamine was depleted by culturing the cells in regularmedium without glutamine and by treating with 2 mM methionine sulfoximine (MSX), an inhibitor of glutaminesynthetase, for 16 hours. The uptake of various amino acids was measured by the use of appropriate substrates andionic conditions. When cultured …

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What Is Your Diagnosis, Pranee Tuntivanich, Suwicha Chuthatep Jul 2012

What Is Your Diagnosis, Pranee Tuntivanich, Suwicha Chuthatep

The Thai Journal of Veterinary Medicine

No abstract provided.

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Ophthalmology Snapshot, Nalinee Tuntivanich Jul 2012

Ophthalmology Snapshot, Nalinee Tuntivanich

The Thai Journal of Veterinary Medicine

No abstract provided.

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The Therapeutic Effects Of Prednisolone In Cats With Immune-Mediated Hemolytic Anemia, Rosama Pusoonthornthum, Parkorn Limlenglert, Pitcha Pornmingmas, Anudep Rungsipipat, Pinit Pusoonthornthum Jul 2012

The Therapeutic Effects Of Prednisolone In Cats With Immune-Mediated Hemolytic Anemia, Rosama Pusoonthornthum, Parkorn Limlenglert, Pitcha Pornmingmas, Anudep Rungsipipat, Pinit Pusoonthornthum

The Thai Journal of Veterinary Medicine

The present study was performed to find the therapeutic effects of 2 mg/kg prednisolone orally fed twice a day in cats with immune-mediated hemolytic anemia (IMHA). Six IMHA positive cats were diagnosed with Coomb’s test. Mean age of IMHA cats was 4.4 years old. They were considered as having secondary IMHA. The mortality rate of IMHA cats received prednisolone treatment was 33.3%. Complete blood count and blood chemistry values were all within the normal limit.

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Ultrasound Diagnosis, Phiwipha Kamonrat Jul 2012

Ultrasound Diagnosis, Phiwipha Kamonrat

The Thai Journal of Veterinary Medicine

No abstract provided.

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Prevalence Of Gastrointestinal Parasites In Yellow Cattle Between Taiwan And Its Offshore Islands, Kwong-Chung Tung, Chiu-Chen Huang, Chien-Hung Pan, Cheng-Hsiung Yang, Cheng-Hung Lai Jul 2012

Prevalence Of Gastrointestinal Parasites In Yellow Cattle Between Taiwan And Its Offshore Islands, Kwong-Chung Tung, Chiu-Chen Huang, Chien-Hung Pan, Cheng-Hsiung Yang, Cheng-Hung Lai

The Thai Journal of Veterinary Medicine

A total of 310 fecal samples of yellow cattle were collected in Taiwan and its offshore islands Penghu andKinmen for gastrointestinal parasite examination using coprological techniques. The overall prevalence was 73.2%.The infection rates of protozoa, nematodes, trematodes, and cestodes were 57.7%, 37.7%, 17.1%, and 0.6%,respectively. Among all parasites, Cryptosporidium spp. (41.6%) were the most predominant, followed by strongyles(36.1%) and Eimeria spp. (11.9%). There were significant differences in the prevalence of protozoa and nematodesbetween different distributional area groups. The present study demonstrates that gastrointestinal parasiticinfections, particularly protozoan infections, occur frequently in yellow cattle in Taiwan and its offshore islands. Theresults indicate …

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Plasmid Profiles Of Multidrug-Resistant Escherichia Coli From Clinically Healthy Swine, Khin Khin Lay, Nisit Chansong, Rungtip Chuanchuen Jul 2012

Plasmid Profiles Of Multidrug-Resistant Escherichia Coli From Clinically Healthy Swine, Khin Khin Lay, Nisit Chansong, Rungtip Chuanchuen

The Thai Journal of Veterinary Medicine

A total of 145 Escherichia coli isolates originated from clinically-healthy pigs were analyzed for plasmidprofiles. All but one isolate (n=144) carried one to nine plasmids with size ranging from 0.7-16.2 Mda. Fifty-sixplasmid profiles were defined based on sizes and numbers of plasmids in each strain, of which the most commonpatterns were 15.8, 4, 3.3, 1.7, 1.3 Mda and 16.2, 15.8, 4, 3.3, 2.3, 1.7, 1.3, 1, 0.7 Mda. The results indicate widedistribution of plasmids among the commensal E. coli isolates originated from clinically-healthy pigs.

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South Dakota Animal Disease Research & Diagnostic Laboratory User's Guide, Animal Disease Research And Diagnostic Laboratory, South Dakota State University Jun 2012

South Dakota Animal Disease Research & Diagnostic Laboratory User's Guide, Animal Disease Research And Diagnostic Laboratory, South Dakota State University

South Dakota Animal Disease Research and Diagnostic Laboratory (ADRDL)

The ADRDL is an accredited AAVLD laboratory and a member of the USDA National Animal Health Network. This document is user's guide for the services provided by the Animal Disease Research and Diagnostic Laboratory.

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Raccoon Acclimation Towards Traps And Its Effect On Surveillance And Monitoring Of Zoonotic Diseases, Lindsay Rollend May 2012

Raccoon Acclimation Towards Traps And Its Effect On Surveillance And Monitoring Of Zoonotic Diseases, Lindsay Rollend

Master's Theses

Raccoons (Procyon lotor) serve as a source of infection with various pathogens for people, most notably, rabies. Raccoons are specifically targeted for the control of rabies in the United States, primarily due to the 100% fatality rate in humans and animals. There is no cure or treatment for rabies and vaccines may be administered to people if it is administered promptly. In order to evaluate how successful trapping of raccoons is by using conventional methods, motion sensing cameras were placed on traps in order to captured raccoon behaviors. Pictures were coded based on these behaviors (around the trap but not …

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Recombinant Protein Production In Bacillus Species, Isolation And Methionine Production In Methionine-Producing Microorganisms, Suwat Saengkerdsub May 2012

Recombinant Protein Production In Bacillus Species, Isolation And Methionine Production In Methionine-Producing Microorganisms, Suwat Saengkerdsub

Graduate Theses and Dissertations

Linoleic acid isomerase (LAI) is the enzyme that converts linoleic acid to conjugated linoleic acids (CLAs) which appear to be capable of lowering cancer risk and enhancing immunity. There is an interest in developing commercial processes for the production of single isomers of CLA by biotransformation of LA using microbial cells and enzymes. However, the evaluation of these strains suggest that growth and LA isomerase production levels by these anaerobes are insufficient to support economic commercial production of single CLA isomers. A better alternative is to clone the isomerase gene and to generate new production strains using recombinant technology. Bifidobacterium …

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Modeling Of The Efficacy And Effectiveness Of Escherichia Coli O157:H7 Pre-Harvest Interventions, Amanda R. Vogstad May 2012

Modeling Of The Efficacy And Effectiveness Of Escherichia Coli O157:H7 Pre-Harvest Interventions, Amanda R. Vogstad

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Shiga toxin-producing Escherichia coli O157:H7 (STEC O157) is one of the leading causes of hemolytic uremic syndrome in humans. Reducing the prevalence of STEC O157 in live cattle may reduce ground beef prevalence and subsequent human illness. Type III secreted protein vaccines (TTSP) reduce fecal shedding of STEC O157 in cattle. However, pre-harvest vaccines have yet to be adopted by the beef industry. The objectives of this thesis were to 1) conduct a meta-analysis to test factors effecting efficacy of a 3-dose regimen TTSP vaccine product, and 2) use stochastic simulation to model the usefulness of preharvest control measures. In …

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Cell-Mediated Immunity In Porcine Reproductive And Respiratory Syndrome Virus, Rajeshwari Parida May 2012

Cell-Mediated Immunity In Porcine Reproductive And Respiratory Syndrome Virus, Rajeshwari Parida

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Porcine reproductive and respiratory syndrome virus is a significant swine pathogen which exhibits considerable sequence diversity. In an attempt to identify highly conserved T-cell epitopes contained in proteins of this virus, we examined heptadecamer peptides spanning the sequence of the PRRSV nonstructural proteins 9, 10 and 11, all of them are highly conserved, for their ability to elicit a recall proliferative and interferon-gamma response in peripheral blood mononuclear cells obtained from pigs immunized against the type-II PRRSV strain FL-12. These studies led to the identification of seven peptides, two from each NSP 9 and NSP 10 and, three from NSP …

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Effects Of Respiratory Vaccination Timing And Hormonal Growth Implant On Health, Performance, And Immunity Of Newly Received Stocker Calves, Kimberly Denise Poe May 2012

Effects Of Respiratory Vaccination Timing And Hormonal Growth Implant On Health, Performance, And Immunity Of Newly Received Stocker Calves, Kimberly Denise Poe

Graduate Theses and Dissertations

Stress alters the immune system and vaccination during this time may reduce vaccine response; whereas, growth implants may shift metabolism to enhance tissue deposition in exchange for energy required for immune response during bovine respiratory disease (BRD) challenge. This study was conducted to determine the effects of pentavalent respiratory vaccination timing with or without a hormonal growth implant on arrival (d 0) on health, performance, complete blood count, and vaccine response in high&ndashrisk, newly received stocker calves during a 42&ndashd receiving period. Crossbred bull and steer calves (n = 385) were weighed (initial BW = 202 ± 4.1 kg), stratified …

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The Presence Of Alpha Interferon At The Time Of Infection Alters The Innate And Adaptive Immune Responses To Porcine Reproductive And Respiratory Syndrome Virus, Susan L. Brockman, Crystal A. Loving, Eric A. Nelson, Laura C. Miller, Tracy L. Nicholson, Karen B. Register, Marvin J. Grubman, Douglas E. Brough, Marcus E. Kehrli Jr Apr 2012

The Presence Of Alpha Interferon At The Time Of Infection Alters The Innate And Adaptive Immune Responses To Porcine Reproductive And Respiratory Syndrome Virus, Susan L. Brockman, Crystal A. Loving, Eric A. Nelson, Laura C. Miller, Tracy L. Nicholson, Karen B. Register, Marvin J. Grubman, Douglas E. Brough, Marcus E. Kehrli Jr

Veterinary and Biomedical Sciences Faculty Publications

Porcine reproductive and respiratory syndrome (PRRS) is one of the most devastating and costly diseases to the swine industry worldwide. Overall, the adaptive immune response to PRRS virus (PRRSV) is weak, which results in delayed elimination of virus from the host and inferior vaccine protection. PRRSV has been shown to induce a meager alpha interferon (IFN-α) response, and we hypothesized that elevated IFN-α levels early in infection would shorten the induction time and increase elements of the adaptive immune response. To test this, we measured both antibody and cell-mediated immunity in pigs after the administration of a nonreplicating human adenovirus …

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Growing South Dakota (Spring 2012), College Of Agriculture &. Biological Sciences Apr 2012

Growing South Dakota (Spring 2012), College Of Agriculture &. Biological Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Powerful Potential: Growing Global Population Spurs Need for Agbioscience
[Page] 4 Spring College News
[Page] 6 Enhanced Education: Students Complement Coursework With Extra-Curricular Opportunities
[Page] 8 Gaining Global Perspective: SDSU Delegation Visits Argentina
[Page] 9 Creative Collaboration: Students, Landowners & Industry Professionals Pair Up for a Positive Experience
[Page] 10 Wondrous Wheat: New Research Agreement & Wheat Varieties Announced
[Page] 12 Here and There
[Page] 14 New Era Underway: SDSU Extension Re-Energizes Programs, Delivery [Page] 16 iGrow Continues to Grow
[Page] 18 Focused on the Future: Field Specialists Strive to Serve Changing Landowner Needs
[Page] 19 Connecting with …

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The Effect Of Neutering On The Risk Of Urinary Incontinence In Bitches – A Systematic Review, W. Beauvais, J. M. Cardwell, D. C. Brodbelt Apr 2012

The Effect Of Neutering On The Risk Of Urinary Incontinence In Bitches – A Systematic Review, W. Beauvais, J. M. Cardwell, D. C. Brodbelt

Endocrinology Collection

An increased risk of urinary incontinence in bitches has often been associated with previous ovariohysterectomy but remains controversial. The objective of this study was to evaluate the strength of evidence for an association between neutering or age at neutering and urinary incontinence in bitches and to estimate the magnitude of any effect found. A systematic review of peer‐reviewed original English analytic journal articles was conducted, based on Cochrane guidelines (Higgins and Green 2009) Of 1,853 records screened, seven studies were identified that examined the effect of neutering or age at neutering on the risk of urinary incontinence but …

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Inflammatory Responses To Induced Infectious Endometritis In Mares Resistant Or Susceptible To Persistent Endometritis, Mette Christoffersen, Elizabeth Woodward, Anders M. Bojesen, Stine Jacobsen, Morten R. Petersen, Mats H. T. Troedsson, Henrik Lehn-Jensen Mar 2012

Inflammatory Responses To Induced Infectious Endometritis In Mares Resistant Or Susceptible To Persistent Endometritis, Mette Christoffersen, Elizabeth Woodward, Anders M. Bojesen, Stine Jacobsen, Morten R. Petersen, Mats H. T. Troedsson, Henrik Lehn-Jensen

Veterinary Science Faculty Publications

BACKGROUND: The objective of the study was to evaluate the gene expression of inflammatory cytokines (interleukin [IL]-1β, IL-6, IL-8, IL-10, tumor necrosis factor [TNF]-α, IL-1 receptor antagonist [ra] and serum amyloid A (SAA) in endometrial tissue and circulating leukocytes in response to uterine inoculation of 105 colony forming units (CFU) Escherichia coli in mares. Before inoculation, mares were classified as resistant or susceptible to persistent endometritis based on their uterine inflammatory response to infusion of 109 killed spermatozoa and histological assessment of the endometrial quality. Endometrial biopsies were obtained 3, 12, 24 and 72 hours (h) after bacterial inoculation and …

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Genetically Engineered Equine Influenza Virus And Uses Thereof, Peter Palese, Adolfo Garcia-Sastre, Thomas Chambers Mar 2012

Genetically Engineered Equine Influenza Virus And Uses Thereof, Peter Palese, Adolfo Garcia-Sastre, Thomas Chambers

Veterinary Science Faculty Patents

The present invention relates, in general, to attenuated equine influenza viruses having an impaired ability to antagonize the cellular interferon (IFN) response, and the use of such attenuated viruses in vaccine and pharmaceutical formulations. In particular, the invention relates to attenuated equine influenza viruses having modifications to an equine NS1 gene that diminish or eliminate the ability of the NS1 gene product to antagonize the cellular IFN response. These viruses replicate in vivo, but demonstrate decreased replication, virulence and increased attenuation, and therefore are well suited for use in live virus vaccines, and pharmaceutical formulations.

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Impact Of Preexisting Adenovirus Vector Immunity On Immunogenicity And Protection Conferred With An Adenovirus-Based H5n1 Influenza Vaccine, Aseem Pandey, Neetu Singh, Sai V. Vemula, Laurent Couetil, Jacqueline M. Katz, Ruben Donis, Suryaprakash Sambhara, Suresh K. Mittal Mar 2012

Impact Of Preexisting Adenovirus Vector Immunity On Immunogenicity And Protection Conferred With An Adenovirus-Based H5n1 Influenza Vaccine, Aseem Pandey, Neetu Singh, Sai V. Vemula, Laurent Couetil, Jacqueline M. Katz, Ruben Donis, Suryaprakash Sambhara, Suresh K. Mittal

Department of Comparative Pathobiology Faculty Publications

The prevalence of preexisting immunity to adenoviruses in the majority of the human population might adversely impact the development of adaptive immune responses against adenovirus vector-based vaccines. To address this issue, we primed BALB/c mice either intranasally (i.n.) or intramuscularly (i.m.) with varying doses of wild type (WT) human adenovirus subtype 5 (HAd5). Following the development of immunity against HAd5, we immunized animals via the i.n. or i.m. route of inoculation with a HAd vector (HAd-HA-NP) expressing the hemagglutinin (HA) and nucleoprotein (NP) of A/Vietnam/1203/ 04 (H5N1) influenza virus. The immunogenicity and protection results suggest that low levels of vector …

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