Medicine and Health Sciences Commons^™

Toxicological Effects And Treatment Of Accidental Ingestion Of Simparica Trio® In Felis Catus: An Investigative Review, Aussia Stander

Honors Theses

Simparica TRIO^®, a canine endectocide manufactured by Zoetis, contains sarolaner, moxidectin, and pyrantel pamoate salt in an orally administered chewable tablet. These compounds are all toxic to both cats and dogs in sufficient amounts. As Simparica TRIO^® rises in popularity among pet owners, Felis catus (felines, cats) in multi-pet households (households with both cats and dogs) are at increased risk of overdosage and toxicosis from accidental ingestion of Simparica TRIO^® due to their smaller weight.

Simparica TRIO^® is not for feline use and little literature exists on the symptoms of and treatment for accidental ingestion …

Stifle Joint Reconstruction Technique Using Fascia Lata In A Cat With Cranial Cruciate Ligament Rupture, Hern-Yeu Lee, Wei-Yau Shia, Tien-Huan Hsu, Wei-Ming Lee

The Thai Journal of Veterinary Medicine

A two-year-old spayed female mongrel cat presenting with right hind limb lameness with intermittent weight bearing while walking was taken to the veterinary medicine teaching hospital of National Chung Hsing University. Both drawer test and tibial compression test were positive, stifle radiography showed synovial fluid had become more radiopaque. The tentative diagnosis for the cat was rupture of the right cranial cruciate ligament (CrCL), medical management using corticosteroids was prescribed with anticoagulants and surgical treatment recommended. Intracapsular reconstruction was performed and the postoperative recovery of this cat presented normal physical status with improved right hind limb weight-bearing activity. This report …

Feline Inductive Odontogenic Tumor In A Young Cat, Chakkarin Satthathum, Sunee Kunakornsawat, Chaiyan Kasorndorkbua

The Thai Journal of Veterinary Medicine

A 6-month-old, 4.45 kg, intact, male domestic shorthair cat was presented with a gingival mass located on the left rostral maxilla and second left upper premolar tooth. Intraoral x-ray of the left rostral maxilla revealed left maxilla bone lysis with a unilocular cystic lesion. The cytology result revealed an epithelial cell tumor .A left rostral maxillectomy was performed and the tumor was submitted for histological assessment .Histopathological diagnosis of the tissue revealed a feline inductive odontogenic tumor .There was no evidence of tumor recurrence 24 months after surgery.

Gangliosidoses In Cats, Latticha Pluemhathaikij, Waruntip Bunyaputikul, Katriya Chankow, Benchaphorn Limcharoen, Nardtiwa Chaivoravitsakul, Rampaipat Penchome, Sawang Kesdangsakonwut, Kasem Rattanapinyopituk, Wijit Banlunara

The Thai Journal of Veterinary Medicine

Two 3-month-old, male, domestic short hair, cats of the same litter were presented to the small animal teaching hospital with the clinical sign of head tremor for 2 weeks. Three months later, the clinical sign had worsened. Both kittens had loss of balance and showed intention tremor. Physical examination revealed hypertelorism, depressed bridge of the nose and back pain. Radiography showed shortened cervicothoracic vertebral bodies. Both kittens died at 8 and 9 months of age, case no.1 and 2 respectively. Both carcasses were submitted for necropsy. Both brains were grossly normal. The costal cartilages of both cats were deformed into …

Anesthetic Effects Of Dexmeditomidine-Tiletamine/Zolazepam Combination In Cats Undergoing Ovariohysterectomy, Nunnapas Jiwlawat, Cholawat Pacharinsak, Sumit Durongphongtorn

The Thai Journal of Veterinary Medicine

Common injectable anesthetics in cats are alpha-2 receptor agonists and tiletamine/zolazepam. Xylazine shows higher rate of side effects because its lower specificity to alpha-2 receptors than dexmeditomidine. However, the use of drug combinations in cats is not much known. Therefore, alternative anesthetic combination should be investigated. Here, we examined the use of tiletamine/zolazepam with two doses of dexmedetomidine in cats. A total of 24 female cats, weight 3.05 ± 0.10 kg (mean ± SEM). Cats were randomly blinded given intramuscularly injection (IM) with either of such drug combination, representing dosage of low dose dexmedetomidine 7.5 μg/kg with tiletamine/zolazepam 3 mg/kg; …

Determination Of Acrylamide Using The Immuno-Enzymatic Method In Commercial Dog And Cat Foods, Ni̇met Kiliç, Bi̇lal Cem Li̇man

Turkish Journal of Veterinary & Animal Sciences

Pet animals raised by humans do not have the chance to choose their own food. Therefore, mistakes made by humans in feeding dogs and cats will adversely affect the health of the animal. There are applications at high temperatures at various stages during the production of dog and cat foods. It is predicted that acrylamide (AA) can be formed as a result of a possible Maillard reaction since the cat and dog foods contain starch in its structure. The aim of this study is to determine the AA residue immuno-enzymatically in dry cat and dog feeds from different companies available …

Successful Treatment Of Demodicosis Due To Demodex Cati In A Cat Using Spot – On Formulation Of Fluralaner, Piyarat Chansiripornchai, Niwat Chansiripornchai

The Thai Journal of Veterinary Medicine

This case report describes the successful use of fluralaner in treating demodicosis caused by Demodex cati in a cat. A 4.2 kg 10 – year – old spayed female Siamese short – haired cat was presented with a 5 – month history of severe dermatitis. The cat had been treated at previous animal hospitals with a variety of drugs such as antimicrobials, glucocorticoids and ectoparasiticides on separate occasions but the clinical signs remained severe. Microscopic examination of skin samples revealed the presence of D. cati. The cat was treated with a single dose of spot – on formulation of fluralaner …

The Feasibility And Image Quality Of Using Soft Embalming Cadaver Dogs And Cats For Radiographic And Ultrasonographic Training, Chutimon Thanaboonnipat, Nan Choisunirachon, Chalika Wangdee, Srireepong Kiertkrittikhoon, Voraphan Na Songkhla, Sirakarnt Dhitavat, Chanyaratt Chaichareonchon, Lampetch Vimuktalop, Kiatpichet Komin

The Thai Journal of Veterinary Medicine

Diagnostic imaging techniques, especially radiography and ultrasonography, have been applied as routine diagnostic tools in clinical practice of both human and veterinary medicine. Soft embalmed cadavers by Thiel’s method is a new method for preserving dead bodies that has been increasingly used in medical education especially in diagnostic imaging fields. The aims of this study were, first, to examine the feasibility of using canine and feline soft cadavers in radiographic and ultrasonographic study and training. Second, to evaluate the procedure score and image quality score of radiography and ultrasonography using the soft cadaver dogs and cats as the model. All …

Left Lateral Liver Lobe Torsion In A Siamese Cat, Dongwook Kim, Ki-Jeong Na, Dongwoo Chang, Gonhyung Kim

The Thai Journal of Veterinary Medicine

A 6-year-old neutered male Siamese cat was presented with an acute onset of vomiting, anorexia and lethargy lasting for four days. An abdominal mass was palpated on physical examination. The cat showed severe anemia, elevated liver enzymes and hypoalbuminemia. Abdominal ultrasonography revealed a suspected hepatic mass without blood flow within the affected region. Computed tomography was performed to better visualize the abdominal cavity and blood flow. Prompt diagnosis of torsion of the left lateral liver lobe was made and immediate surgery for liver lobectomy was performed. Histopathological examination revealed no evidence of neoplasia. The cat remained clinically normal during the …

Analysis Of Gaps In Feline Ectoparasiticide Purchases From Veterinary Clinics In The United States, Robert Lavan, Dorothy Normile, Imran Husain, Amita Singh, Kathleen Heaney

Publications and Research

Background: The study objective was to examine cat owner ectoparasiticide purchases in the United States and estimate the impact of purchase gaps on timely ectoparasite protection administration. These purchase gaps lead to periods of time when cats are unprotected from ectoparasites.

Methods: Ectoparasiticide purchase transactions for individual cats from 671 U.S. veterinary clinics from January 1, 2017 through June 30, 2019 were evaluated to determine time “gaps” between doses of ectoparasiticides purchased in a defined 12-month period. Ectoparasiticides examined were topically applied products that contained fluralaner, fipronil/(S)-methoprene/pyriproxyfen, imidacloprid/pyriproxyfen or selamectin as active ingredients. The duration of protection following administration of …

In Vitro Investigation On Extracellular Traps Formation Of Cat Polymorphonuclearleucocytes Against Toxoplasma Gondii, Nesli̇han Sürsal Şi̇mşek, Ayşe Çakmak, Kader Yildiz

Turkish Journal of Veterinary & Animal Sciences

Neutrophil granulocytes are one of the most important defenders of the innate immune system in the host. Moreover, neutrophils are able to reach the inflammation area and kill the pathogens using various defense strategies including neutrophil extracellular traps (NETs). However, there is still not enough information available regarding the innate immunity against Toxoplasma gondii in cats that are both definitive and intermediate hosts of this parasite. Therefore, we investigated the in vitro NETs formation which is induced by cat polymorphonuclear leucocytes (PMNs) against T. gondii tachyzoites. Firstly, PMNs were isolated from cat venous blood samples by using discontinues Percoll dilutions …

Molecular And Antigen Detection Of Dirofilaria Immitis Infection In Client-Owned Cats In Bangkok, Thailand, Sukullaya Ritthikulprasert, Pipat Jirapiti, Siwaporn Pengpis

The Thai Journal of Veterinary Medicine

Feline heartworm disease, caused by Dirofilaria immitis infection, can be potentially fatal to cats. Screening for the infection in cats is important in endemic areas. Clinical utility of molecular techniques for diagnosis of feline heartworm disease is not clearly determined. The objective of this study was to evaluate whether a polymerase chain reaction (PCR) assay could be used for detection of D. immitis infection in cats that were concurrently tested for D. immitis antigen. Blood samples were collected from 100 client-owned cats in a veterinary teaching hospital. Whole blood samples were tested for D. immitis antigen and extracted for total …

Surgical Management Of Infectious And Noninfectious Melting Corneal Ulcers In Cats, Aynur Demi̇r, Yusuf Altundağ, Gülşen Sevi̇m Karagözoğlu

Turkish Journal of Veterinary & Animal Sciences

A melting ulcer, characterized by the stromal dissolution of the cornea, is an important eye lesion that develops due to various reasons and threatens vision. Restoration of this lesion, which causes loss of corneal transparency, requires aggressive medical and surgical treatment. In medical treatment, stromal degeneration is controlled with agents that support topical antibacterial and stromal healing. Surgical treatment is applied using various techniques to remove structures damaged due to the progression of corneal melting and to promote corneal healing. In this study, lamellar keratectomy and the third eyelid flap techniques were combined with topical medical therapy in 20 cat …

Bullet-Induced Chronic Cystitis In Cat, Jutapoln Sunghan, Nattakarn Khantaprab, Atigan Thongtharb

Turkish Journal of Veterinary & Animal Sciences

A two-year-old male domestic short hair cat was referred with a history of lower urinary tract obstruction. Four months previously, this animal showed clinical signs of hematuria. On physical examination, the cat showed signs of mild abdominal cramping and painful urination or dysuria. Abdominal radiography was also performed, and the result showed a radiopaque material-a bullet- within the bladder lumen. Cystotomy was performed to remove the bullet from the urinary bladder. At that time, amikacin was used according to bacterial culture (Enterobacter spp.) and drug susceptibility results. Three weeks after surgery, the cat was presented to the Small Animal Hospital …

Survival Time And Prognosis Factors In Hypertrophic Cardiomyopathy Cats With Congestive Heart Failure, Lalida Tantisuwat, Panduangjai Puangampai, Pornchanok Panpakdee, Thitinan Tangarsasilp, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

Hypertrophic cardiomyopathy (HCM) is a common myocardial disease in cats. Nowadays, there is no study determining the survival time of cats affected with HCM in Thailand. This study aimed to evaluate the survival time in HCM cats with congestive heart failure (CHF) in Thailand and to determine the factors associating with survival time. A retrospective study was performed in 47 HCM cats to analyze survival time and the association of survival time and factors including sex, age, breeds, weight, physical findings, the presence of complications, medication and echocardiographic findings. The data was analyzed by the Log-Rank test and displayed with …

Prevalence Of Feline Immunodeficiency Virus & Feline Leukemia Virus In Clinically Healthy Cats In Khon Kaen Province, Kawintra Aiyaranoi, Nichapart Boonchalaew, Natcha Chawnan, Sukdiphat Chotiku, Jaruwan Kampa

The Thai Journal of Veterinary Medicine

FIV and FeLV infections are mostly studied among clinically sick cats; therefore, results may deviate from the true prevalence in a whole population. By using a commercially available kit, the infections were observed in 216 clinically health client-owned cats in Khon Kaen province, Thailand. A cross-sectioned study was undertaken to estimate the presence of FIV and FeLV infections in the cats which underwent health checkup from October 2016 to January 2017. The prevalence of FIV-antibody positive and FeLV-antigenic cats were 6.1% and 3.1%, respectively, and co-infection was not identified. The updated information provides necessary guidelines for veterinarians to provide preventive …

Uterine Prolapse In A Pregnant Cat, Zeynep Günay Uçmak, Meli̇h Uçmak, Ali̇ Can Çeti̇n, Çağatay Tek

Turkish Journal of Veterinary & Animal Sciences

A 3-year-old, 2.5-kg British shorthair cat with dystocia and protrusion of a mass through the vulva was presented to the Obstetrics and Gynaecology Clinic, Faculty of Veterinary Medicine, İstanbul University. Upon clinical examination, a complete uterine prolapse was diagnosed. Because of a blood blister and oedema in the uterine horns, ovariohysterectomy treatment was decided. During laparotomy, one foetus was detected in the cranial portion of the left uterine horn. After manual reduction and intraabdominal withdrawal of the prolapsed uterus, a caesarean section was performed to deliver the foetus. The last litter and the queen were discharged from the clinic in …

New Methods To Differentiate Cardiac And Non-Cardiac Disease Cats From Thoracic Radiographs, Pakapol Fucharoen, Wannisa Pankham, Siwakorn Thong-In, Sirapop Juengthanasomboon, Sirilak Disatian Surachetpong

The Thai Journal of Veterinary Medicine

The objective of this study was to distinguish between cats with cardiac disease and non-cardiac disease by using parameters obtained from thoracic radiographs. This study was performed in 49 cats with a mean age of 7.7±4.79 years. Weight, sex and breed of all cats were randomly chosen. Echocardiography was used as a gold standard to diagnose cardiac disease and separate the cats into two groups, cardiac disease (n=31) and non-cardiac disease (n=18). Five parameters were measured from the right lateral radiographs including 1) the cardiac length (L), 2) the cardiac width (W), 3) the width of the caudal vena cava …

Portosystemic Shunts In Cats: Management And Care, Rachael E. Konke

Master of Arts in Professional Writing Capstones

Portosystemic Shunts in Cats: Management and Care is an informative technical manual developed for veterinary professionals and caretakers of cats with portosystemic shunts. A portosystemic shunt is a complex and rare circulatory deformity in which unfiltered blood bypasses the liver and circulates throughout the body causing serious complications. Portosystemic Shunts in Cats: Management and Care details portosystemic specifics, symptoms, treatment, and proper everyday care for cats with portosystemic shunts.

The Treatment Of Supracondylar And Diaphyseal Femoral Fractures Incats Using Intramedullary Two-Way Stacked Kirschner Wire Application, Kemal Altunatmaz, Murat Karabağli, Di̇dar Aydin, Özlem Güzel, Ebru Eravci Yalin, Ümi̇t Uğurlu, Defne Joan Şadalak, Hi̇mmet Eki̇ci̇

Turkish Journal of Veterinary & Animal Sciences

Femoral fractures in cats are treated using pin and wires, lag screws, Rush pins, intramedullary threaded pins, interlocking pins, clamp rod internal fixators, and plates or plate-rods. In this study, 14 cats brought to the surgery clinic between the years 2010 and 2015 for fracture, due to either a road traffic accident or falling from a height, were evaluated. Following clinical and radiological examination of the cases, the type and location of the fracture, details of the applied fixation method, and postoperative clinical and radiological results were assessed. Localization of the fractures was as follows: 4 comminuted diaphyseal (1 segmental), …

Efficacy Of 10% W/V Fipronil Spot-On Against Tick (Rhipicephalus Sanguineus) Infestation On Cats, Sonthaya Tiawsirisup, Wilai Rattanatayarom

The Thai Journal of Veterinary Medicine

The efficacy of 10% w/v fipronil spot-on for treatment and prevention of Rhipicephalus sanguineus infestation on cats was examined. Twelve cats were randomly allocated into two groups which were the treatment and control groups. The treatment group received 10% fipronil spot-on at a dosage of 6.7 mg/kg on day 0. A group of 60 R. sanguineus was released to feed on each cat on days -7, -2, 3, 7, 14, 21, and 28. The ticks were counted and removed on days -4, 3, 6, 10, 17, 24, and 31. The infested ticks on the cats were also counted but not …

Identification Of Feline Tritrichomonas Foetus Surface Epitopes: Putative Targets For Development Of A Novel Diagnostic Test For Feline Trichomonosis, Emily Nissa Gould

Masters Theses

BACKGROUND: Tritrichomonas foetus (T. foetus) is a flagellated protozoa that infects the distal ileum and proximal colon of domestic cats and also induces reproductive failure in cattle. Although feline trichomonosis is recognized to have a global prevalence of up to 30%, it still poses a diagnostic and therapeutic challenge to veterinarians; thus, there is a need for both improved diagnostics and therapeutics. Despite differing organ tropism between genotypes, evidence exists for conserved virulence factors between feline and bovine T. foetus. Two epitopes (1.15 and 1.17) of the bovine T. foetus glycosylated surface antigen 1.15-1.17 have been found …

Immunohistochemical Evaluation Of Canine And Felinemerkel Cell Tumors?A Report Of Two Cases, Mateusz Mikiewicz, Iwona Otrocka-Domagala, Katarzyna Pazdzior-Czapula, Michal Gesek, Anna Mikolajczyk, Agnieszka Blacha

Turkish Journal of Veterinary & Animal Sciences

Merkel cell tumors, a type of cutaneous round-cell tumors, are rarely observed in dogs and cats. This tumor type originates from cutaneous neuroendocrine cells. In the present study, the morphology of canine and feline Merkel cell tumors and their immunoexpression of neuron-specific enolase, cytokeratin, chromogranin A, Ki67, and metallothionein were evaluated using histopathological and immunohistochemical methods. The canine Merkel cell tumor displayed a diffuse morphological pattern, whereas the feline tumor displayed a solid morphological pattern. Both tumors were positive for neuron-specific enolase and cytokeratin, but negative for chromogranin A. The Ki67 indexes in the canine and feline tumors were 7% …

Treatment Of Microsporum Canis Infection In A Cat Using A Fungal Vaccine, Piyarat Chansiripornchai, Nipattra Suanpairintr

The Thai Journal of Veterinary Medicine

Successful treatment of Microsporum canis infection in a 8 - year – old, male Thai - mixed breed cat using a fungal vaccine containing inactivated M. canis by 3 subcutaneously injection 14 days apart was reported. A reduction of the lesions and hair regrowth had improved by day 14 after the first injection. There were no adverse effects in the cat during the entire treatment. The results of this study indicate that an inactivated M. canis vaccine may be effective therapy for M. canis infection.

The Multidrug-Resistant Pseudomonas Aeruginosa Clinical Isolates From Dogs And Cats Expressed Three Multidrug Efflux Systems Simultaneously, Kanchana Poonsuk, Rungtip Chuanchuen

The Thai Journal of Veterinary Medicine

The objective of this study was to examine the expression of 4 clinically-important Mex systems including MexAB-OprM, MexCD-OprJ, MexEF-OprN and MexXY in the Pseudomonas aeruginosa clinical isolates from dogs and cats. The isolates exhibited high level of resistance to multiple antibiotics clinically important. All of them simultaneously overexpressed up to three different Mex systems, including MexAB-OprM, MexEF-OprN and MexXY as determined by RT-PCR. None of the isolates overexpressed MexCD-OprJ. Expression of mexF was measured by using quantitative real-time RT-PCR. Transcription level of mexF varied (i.e. 4-219 fold) but was at least 4 fold higher than that of PAO1. DNA sequence …

Recombinant Human Follicle Stimulating Hormone And Growth Factors Improve The Meiotic And Developmental Competence Of Cat Oocytes, Theerawat Tharasanit, Chommanart Thongkittidilok, Thanida Sananmuang, Mongkol Techakumphu

The Thai Journal of Veterinary Medicine

In vitro embryo production has proven as potential tool for understanding factors involving developmental biology of embryos. This study aimed at examining the effects of recombinant human follicle stimulating hormone (rhFSH) on meiotic resumption and also on developmental competence of cat oocytes. Experiment 1 studied mRNA expression of luteinizing hormone (LH), follicle stimulating hormone (FSH), epidermal growth factor (EGF) and insulin like growth factor-1 (IGF-1) receptors (R) in cumulus cells. mRNA expression of LH receptor in cumulus cells after oocyte maturation was additionally examined. Experiment 2 examined the effect of different rhFSH concentrations (0.01, 0.05, 0.1 and 1 IU/ml) on …

Survey Of Toxoplasma Gondii In Taipei: Livestock Meats, Internal Organs, Cat And Dog Sera, Ying-Bin Taiching Fuh, Albert Taiching Liao, Yun-Ming Taiching Pong, Meng-Chih Taiching Tung, Chang-Young Taiching Fei, Dah-Sheng Lin

The Thai Journal of Veterinary Medicine

Toxoplasma gondii (T. gondii) is an important food-borne zoonotic protozoa. Infection occurs when humans and warm-blooded animals consume raw or lightly cooked cysts containing meat or sporulated oocysts contaminated food. T. gondii infection has been observed in food animals in many countries suggesting the significance of food animals in the epidemiology of toxoplasmosis. However, there is no report regarding T. gondii infection in food animals other than pigs in Taiwan. Therefore, in this study, pork, pig livers, mutton, chicken flesh, chicken hearts, chicken livers, gizzards, and imported beef sold in the supermarkets in Taipei were examined for T. gondii deoxyribonucleic …

Cutaneous Asthenia (Ehlers–Danlos Syndrome) In A Cat, Banu Dokuzeylül, Eli̇f Demet Altun, Tamer Hali̇t Özdoğan, Hasan Hakan Bozkurt, Seçki̇n Serdar Arun, Mehmet Erman Or

Turkish Journal of Veterinary & Animal Sciences

Ehlers-Danlos syndrome (EDS), or dermatosparaxis, is a rare hereditary disease of the connective tissue, which is characterized by skin hyperextensibility and laxity. In the present article, the case of a crossbred female spayed cat, at the age of 2 years, was presented with hyperelasticity of the skin, alopecia, and an ulcerative wound on the left hind leg. The animal's dorsum was hyperextensible, smooth to the touch, and could be easily torn with minor traumas. To the best of the authors' knowledge, the present report is the first documented feline case of cutaneous asthenia in Turkey.

Dorsal Luxation Of The Scapula In A Cat, Serhat Özsoy, Özlem Güzel

Turkish Journal of Veterinary & Animal Sciences

Dorsal luxation of the scapula is a rare orthopedic disorder caused by traumatic rupture of the muscles supporting the scapula. The presented case consisted of an adult cat in which luxation of the scapula had occurred due to trauma. During clinical examination, dorsal displacement of the scapula was evident upon manipulation of the limb. Radiological examination did not reveal any fractures or other concurrent injuries. In the surgical treatment of the patient, the muscles were sutured in place. The patient regained its normal gait without any complications within 4 weeks.

Assessment Of Amiodarone Effects On Intact Cats' Electrocardiograms, Farzad Gouya, Ali Shabestari Asl

Turkish Journal of Veterinary & Animal Sciences

Amiodarone can be used for treatment of ventricular and supraventricular arrhythmias in canine medicine, but its exact role in feline electrocardiography and its side effects have not been proven. The aim of this study was the evaluation of amiodarone and its different dosages' effects on intact feline heart electrocardiograms. Eight healthy stray cats were selected and control electrocardiogram was obtained. Amiodarone tablets were prescribed twice daily at 10 mg/kg for 7 days. The same protocol was repeated with doses of 15 and 25 mg/kg. Hexagonal electrocardiograms were obtained at the end of each stage. Electrocardiograms were evaluated for P amplitude …