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Articles 2701 - 2730 of 3580

Full-Text Articles in Pharmacology

Tyrosinase Inhibitors From Artocarpus Lakoocha(สารที่มีฤทธิ์ยับยั้งเอนไซม์ไทโรสิเนสจากมะหาด), Boonchoo Sritularak, Wanchai De-Eknamkul, Kittisak Likhitwitayawuid Jan 1998

Tyrosinase Inhibitors From Artocarpus Lakoocha(สารที่มีฤทธิ์ยับยั้งเอนไซม์ไทโรสิเนสจากมะหาด), Boonchoo Sritularak, Wanchai De-Eknamkul, Kittisak Likhitwitayawuid

The Thai Journal of Pharmaceutical Sciences

Tyrosinase is an enzyme widely distributed in nature. It has been found in plants, fungi and animals. A number of physiological functions of this enzyme have been studied. In human, its function in the biosynthesis of the skin pigment melanin is well est...


Antifungal Drug Therapy For Hiv-Infected Patients Of Bamrasnaradura Hospital(การใช้ยาต้านเชื้อราในผู้ป่วยที่ติดเชื้อ Hiv ที่โรงพยาบาลบำราศน..., Yukontorn Jirapongpitak, Sarinee Krittiyanunt, Winit Winit-Watjana Jan 1998

Antifungal Drug Therapy For Hiv-Infected Patients Of Bamrasnaradura Hospital(การใช้ยาต้านเชื้อราในผู้ป่วยที่ติดเชื้อ Hiv ที่โรงพยาบาลบำราศน..., Yukontorn Jirapongpitak, Sarinee Krittiyanunt, Winit Winit-Watjana

The Thai Journal of Pharmaceutical Sciences

HIV-infected patients are prone to opportunistic infections, especially fungal infection, which need appropriate treatment. This study is intended to examine pathogenic fungi that caused opportunistic fungal infections and the use of antifungal drugs in ...


Pharmacology Of Male Contraceptives(เภสัชวิทยาของยาคุมกำเนิดเพศชาย), Srisombat Nawanopparatsakut Jan 1998

Pharmacology Of Male Contraceptives(เภสัชวิทยาของยาคุมกำเนิดเพศชาย), Srisombat Nawanopparatsakut

The Thai Journal of Pharmaceutical Sciences

Nowadays male contraceptives begin to play an important role. However, the information about drugs that have pharmacological activity as male contraceptives is still limited. Male contraceptive drugs should be safe and provide only short-term effect. Mal...


Medical Savings Accounts, Supakit Wongwiwatthananukit Jan 1998

Medical Savings Accounts, Supakit Wongwiwatthananukit

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Inactivation Of Aminoglycosides By Penicillins And Cephalosporins(การทำให้ยาในกลุ่มอะมิโนกลัยโคซายด์หมดฤทธิ์ โดยยาในกลุ่มเพนนิซิล..., Jinda Wangboonskul, Aporanee Chaiyakum, Tanee Tetsiri Jan 1998

Inactivation Of Aminoglycosides By Penicillins And Cephalosporins(การทำให้ยาในกลุ่มอะมิโนกลัยโคซายด์หมดฤทธิ์ โดยยาในกลุ่มเพนนิซิล..., Jinda Wangboonskul, Aporanee Chaiyakum, Tanee Tetsiri

The Thai Journal of Pharmaceutical Sciences

Faculty of Pharmaceutical Sciences, Khon Kaen University has provided a therapeutic drug monitoring service for Srinagarind Hospital since 1994. However, The service is only available on the working-hour basis. Some submitted samples, therefore, have to ...


Study Of Cardiovascular Activity Of Morinda Citrifolia Fruits(การศึกษาฤทธิ์ของผลยอต่อระบบหัวใจและหลอดเลือด), Uraiwan Permpipat, Puntarika Na Pattaloong Jan 1998

Study Of Cardiovascular Activity Of Morinda Citrifolia Fruits(การศึกษาฤทธิ์ของผลยอต่อระบบหัวใจและหลอดเลือด), Uraiwan Permpipat, Puntarika Na Pattaloong

The Thai Journal of Pharmaceutical Sciences

We previously showed that Morinda citrifolia fruits possess weak anti-dopaminergic activity which may account for its antiemetic activity as recommended in Thai traditional medicine. In this study we examined cardiovascular activity of M. citrifolia to d...


Searching The Internet For Drug Information(การสิบค้นข้อมูลยาบนอินเตอร์เนต), Wanchai Treyaprasert Jan 1998

Searching The Internet For Drug Information(การสิบค้นข้อมูลยาบนอินเตอร์เนต), Wanchai Treyaprasert

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Monoterpene Glycosides And Furan Derivative From Coleus Amboinicus Lour.(โมโนเทอร์ปีนกลัยโคใซด์และอนุพันธ์ฟูรานจากเนียมหูเสือ), Rutt Suttisri, Ratiphan Laungsuwon Jan 1998

Monoterpene Glycosides And Furan Derivative From Coleus Amboinicus Lour.(โมโนเทอร์ปีนกลัยโคใซด์และอนุพันธ์ฟูรานจากเนียมหูเสือ), Rutt Suttisri, Ratiphan Laungsuwon

The Thai Journal of Pharmaceutical Sciences

Extraction of the aerial parts of Coleus amboinicus Lour, yielded two monoterpene glycosides, thymoquinol-P-D-glu copyranoside and carvacrol-p-D -glucopyranoside, and a furan derivative, 5 - (hydroxymethyl)-2-furaldehyde. Identification of the compounds ...


Chemical Stability And Mechanism Of Degradation Of Omeprazole In Solution(ความคงตัวทางเคมีและกลไกการเสื่อมสลายของโอมิปราโซลใน สารละลาย), Narong Sarisuta, Tudsong Tourtip, Siripote Chuarcharoern Jan 1998

Chemical Stability And Mechanism Of Degradation Of Omeprazole In Solution(ความคงตัวทางเคมีและกลไกการเสื่อมสลายของโอมิปราโซลใน สารละลาย), Narong Sarisuta, Tudsong Tourtip, Siripote Chuarcharoern

The Thai Journal of Pharmaceutical Sciences

The chemical stability and kinetics of omeprazole in buffer solutions at various pH values, 5.0, 7.0, 8.0, and 10.0, were studied at three different stress conditions, 25, 40, and 50 °c. It was found that the degradation reaction followed the pseudo fir...


Comparison Of Beta-Adrenoceptor Coupled Camp Production In Cultured Human Mononuclear Leukocytes And Myometrial Cells, Yu-Li Liu Dec 1997

Comparison Of Beta-Adrenoceptor Coupled Camp Production In Cultured Human Mononuclear Leukocytes And Myometrial Cells, Yu-Li Liu

Electronic Theses and Dissertations

$\beta\sb2$-Adrenoceptor ($\beta\sb2$-AR) agonists, such as terbutaline, are used as tocolytic agents in the treatment of preterm labor. $\beta$-Adrenoceptor stimulation relaxes myometrium through specific receptors coupled through Gs to adenylyl cyclase (AC) that catalyzes the conversion of ATP to cAMP. The purpose of this study was to compare $\beta$-adrenoceptors and cAMP production in cultured human leukocytes and myometrial cells, and to determine the importance of $\beta$-adrenoceptors and cAMP production in isoproterenol-induced myometrial relaxation. $\sp{125}$I-iodopindolol was used to assess $\beta$-adrenoceptor affinity and number cAMP levels were analyzed before and after stimulation by isoproterenol, AlF$\sb4\sp-$, forskolin, and PGE$\sb1$. Isometric recording was used to …


Effects Of Lipoproteins On Cyclo-Oxygenase And Lipoxygenase Pathways In Human Platelets, S A. Saeed, R A. Memon, A H. Gilani, B H. Shah Mar 1997

Effects Of Lipoproteins On Cyclo-Oxygenase And Lipoxygenase Pathways In Human Platelets, S A. Saeed, R A. Memon, A H. Gilani, B H. Shah

Department of Biological & Biomedical Sciences

The products of arachidonic acid (AA) metabolism in platelets play an important role in platelet shape change, adhesion and aggregation which may participate in the pathogenesis of ischemic heart disease and thrombosis. Since lipoproteins are also involved in the pathogenesis of thrombo-embolic disorders, the effect of human lipoproteins (HDL, LDL, VLDL) on AA metabolism in human platelets was investigated. Lipoproteins were separated by density gradient zonal ultracentrifugation. The effects of lipoproteins on production of AA metabolites in human platelets i.e., thromboxane A2 (TXA2) and hydroxy-eicosatetraenoic acids (HETEs) were examined using radiometric thin layer chromatography coupled with automated data integrator system. …


A Search For The Cause Of Excess Thiol Sensitivity In A Mutant Of Escherichia Coli, Hongying Zeng Mar 1997

A Search For The Cause Of Excess Thiol Sensitivity In A Mutant Of Escherichia Coli, Hongying Zeng

Loma Linda University Electronic Theses, Dissertations & Projects

The subject of this study was a search for the biochemical basis of hypersensitivity to thiols in a mutant of Escherichia coli (IS16). A 1.3 kb chromosomal fragment from E. coli (introduced into the mutant on a plasmid) successfully abolished the hypersensitivity. This fragment contained only one intact gene, ubiX, which codes for polyprenyl-4-hydroxybenzoatelyase. The decarboxylation of octaprenyl-4- hydroxybenzoate in E. coli is catalyzed not only by the ubiX protein but also by the product of ubiD. The ubiquinone content of IS16 was only 2% of that of its parent strain, while the complementing plasmid increased it …


Preparation And Potency Testing Of Long Acting Tetanus Toxoid Microcapsules, Ubonthip Nimmannit, Suchada Natesuwon Jan 1997

Preparation And Potency Testing Of Long Acting Tetanus Toxoid Microcapsules, Ubonthip Nimmannit, Suchada Natesuwon

The Thai Journal of Pharmaceutical Sciences

In recent years, attempts have been made to develop microcapsule-type tetanus toxoid with the aim of prolonging the potency of tetanus toxoid to reduce the frequency of immunization. A non-toxic, biocompatible and biodegradable substance like egg yolk le...


Gynecomastia, ปารณีย์ มีแต้ม Jan 1997

Gynecomastia, ปารณีย์ มีแต้ม

The Thai Journal of Pharmaceutical Sciences

Gynecomastia เป็นภาวะปกติที่พบในทารก ชายวัยรุ่น และผู้สูงอายุ นอกจากนั้นยังเป็นพยาธิ สภาพเนื่องจ...


Behavior Of Loading A Drug Onto Cation Exchange Resins By Batch Multiple Equilibria Method(พฤติกรรมการนำยาเข้าสู่เรซินแลกเปลี่ยนอิออนประจุบวก โดยว..., Prasert Akkaramongkolporn Jan 1997

Behavior Of Loading A Drug Onto Cation Exchange Resins By Batch Multiple Equilibria Method(พฤติกรรมการนำยาเข้าสู่เรซินแลกเปลี่ยนอิออนประจุบวก โดยว..., Prasert Akkaramongkolporn

The Thai Journal of Pharmaceutical Sciences

The drug resin complexes prepared by the batch multiple equilibria method with various series of concentrations and volumes of drug solutions were investigated. The percent exchange (P ) of drug at equilibrium decreased with increase in the initial conce...


Developing Diabetes Pharmaceutical Care Databases (Dpcd), Education And Teaching Documentation Record (Etdr) In Community Pharmacy, Supakit Wongwiwatthananukit Jan 1997

Developing Diabetes Pharmaceutical Care Databases (Dpcd), Education And Teaching Documentation Record (Etdr) In Community Pharmacy, Supakit Wongwiwatthananukit

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


In Vitro Release Characteristics Of Indomethacin Chitosan Beads, Satit Puttipipatkhachom, Kanya Anantakul Jan 1997

In Vitro Release Characteristics Of Indomethacin Chitosan Beads, Satit Puttipipatkhachom, Kanya Anantakul

The Thai Journal of Pharmaceutical Sciences

Indomethacin chitosan beads were prepared by ionotropic gelation with multivalent tripolyphosphate (TPP) ions. Various process variables such as amount of drug loading, chitosan gel concentration, TPP concentration and gelation time were investigated for...


Amyloid-β Deposition In Rat Brain: Histopathological And Functional Sequelae, Einar M. Sigurdsson Jan 1997

Amyloid-β Deposition In Rat Brain: Histopathological And Functional Sequelae, Einar M. Sigurdsson

Dissertations

No abstract provided.


Characterization Of Adaptive Changes In 5-Htia Receptor Systems Induced By Repeated Injections Of 5-Ht Uptake Inhibitors, Qian Li Jan 1997

Characterization Of Adaptive Changes In 5-Htia Receptor Systems Induced By Repeated Injections Of 5-Ht Uptake Inhibitors, Qian Li

Dissertations

No abstract provided.


เอนไซม์ไซโดโครม พี 450, ศรีสมบัติ นวนพรัตน์สกุล Jan 1997

เอนไซม์ไซโดโครม พี 450, ศรีสมบัติ นวนพรัตน์สกุล

The Thai Journal of Pharmaceutical Sciences

เอนไชม์ไชโตโครม พี 450 เป็นกลุ่มของฮีโมโปรตีนชึ่งมีบทบาทสำคัญในการเร่งการเกิดปฏิกิริยาเค...


Fluorescamine : Characteristics, Scope And Applications(ฟลูโอเรสคามีน : คุณสมบัติ ขอบเขต และ การประยุกต์ใช้ประโยชน์), Lawan Sriphong Jan 1997

Fluorescamine : Characteristics, Scope And Applications(ฟลูโอเรสคามีน : คุณสมบัติ ขอบเขต และ การประยุกต์ใช้ประโยชน์), Lawan Sriphong

The Thai Journal of Pharmaceutical Sciences

Fluorescamine, a fluorometric reagent specific to primary amine compounds, is widely used in the determination of amino acids, amines, peptides, proteins and drugs by fluorometric or spectrofluorometric method, plannar chromatography, high performance li...


Interleukin-2 Fusion Protein: An Investigational Therapy For Interleukin-2 Receptor Expressing Malignancies, Jean Nichols, Foss Francine, Kuzel Timothy, Lemaistre Charles Fred, Platanias Leonidas, Ratain Mark, Rook Alain, Mansoor Saleh, Schwartz Gary Jan 1997

Interleukin-2 Fusion Protein: An Investigational Therapy For Interleukin-2 Receptor Expressing Malignancies, Jean Nichols, Foss Francine, Kuzel Timothy, Lemaistre Charles Fred, Platanias Leonidas, Ratain Mark, Rook Alain, Mansoor Saleh, Schwartz Gary

Haematology and Oncology, East Africa

DAB3s91L-2 is an interleukin-2 receptor (IL-2R) specific fusion protein with a molecular weight of 58 kD containing the enzymatic and translocation domains of diphtheria toxin (DT) and human IL-2. This fusion protein is able to direct the cytocidal action of the DT enzymatic region only to cells which bear the IL-2R. The human IL-2R exists in three forms: low, intermediate and high affinity. The high-affinity form is believed to be the biologically relevant form on mature, activated T-lymphocytes, B-lymphocytes and monocytes. DAB3sgIL-2 is able to bind selectively to the high-affinity IL-2R in a concentration-dependent manner, and once bound is internalised …


503 Phase I Radioimmunotherapy (Rit) Study Of 90y-Cc49 Monoclonal Antibody (Mab) Therapy In Patients With Advanced Non-Small Cell Lung Cancer (Nsclc), Francisco Robert, Ruby Meredith, Michael Khazaeli, Charles Russell, William Grizzle, John Newsome, Mansoor Saleh Jan 1997

503 Phase I Radioimmunotherapy (Rit) Study Of 90y-Cc49 Monoclonal Antibody (Mab) Therapy In Patients With Advanced Non-Small Cell Lung Cancer (Nsclc), Francisco Robert, Ruby Meredith, Michael Khazaeli, Charles Russell, William Grizzle, John Newsome, Mansoor Saleh

Haematology and Oncology, East Africa

503 Phase I radioimmunotherapy (RIT) study of 90Y-CC49 monoclonal antibody (MAb) therapy in patients with advanced non-small cell lung cancer (NSCLC) × Close The Infona portal uses cookies, ie strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms …


Colonic Drug Delivery : Study And Strategy(การนำส่งยาทางลำไส์ใหญ่ : การศึกษาและกลยุทธ์การนำส่ง), Thawatchai Phaechamud Jan 1997

Colonic Drug Delivery : Study And Strategy(การนำส่งยาทางลำไส์ใหญ่ : การศึกษาและกลยุทธ์การนำส่ง), Thawatchai Phaechamud

The Thai Journal of Pharmaceutical Sciences

Many investigators have designed oral preparations to deliver compounds to human colon. The colon provides somewhat less hostile environments with lesser diversity and intensity o f enzymatic activities as compared to the stomach and the small intestine....


Kinetics Of Drug Loading Onto Cation-Exchange Resins And Effect Of Concurrent Counter-Ions, Prasert Akkaramongkolporn Jan 1997

Kinetics Of Drug Loading Onto Cation-Exchange Resins And Effect Of Concurrent Counter-Ions, Prasert Akkaramongkolporn

The Thai Journal of Pharmaceutical Sciences

The patterns of chlorpheniramine loading onto cation-exchange resins with and without concurrent counter-ions were investigated. All of them were found to give the best fit with the model according to film diffusion-controlled process. The existence of c...


Prevention Action Of Turmeric Against Hcl-Induced Gastric Necrosis In Rat : To Verify The Mode Of Action Of Previous Clinical Study, Ch. Prucksunand, N. Kiatying-Aiigsulee, K. Sawasdimongkol, S. Wimolwattanapun, B. Petchruengrong, K. Tiensong, S. Paeyai Jan 1997

Prevention Action Of Turmeric Against Hcl-Induced Gastric Necrosis In Rat : To Verify The Mode Of Action Of Previous Clinical Study, Ch. Prucksunand, N. Kiatying-Aiigsulee, K. Sawasdimongkol, S. Wimolwattanapun, B. Petchruengrong, K. Tiensong, S. Paeyai

The Thai Journal of Pharmaceutical Sciences

The purposes of this scientific work were to study the mode of action of turmeric in animal and to verify previous clinical data of turmeric action in peptic ulcer patient. Oral administration of 0.6 N HC1 to fasted rats produced extensive necrosis of ga...


Application Of Factorial Design In Development Of Hydrochlorothiazide Tablet Formulation(การใซ Factorial Design ใน การพัฒนาตำรับยาเม็ด ไฮโดรคลอโรใธอาใซด์), Pienkit Dangprasirt, Sansanee Pongwai Jan 1997

Application Of Factorial Design In Development Of Hydrochlorothiazide Tablet Formulation(การใซ Factorial Design ใน การพัฒนาตำรับยาเม็ด ไฮโดรคลอโรใธอาใซด์), Pienkit Dangprasirt, Sansanee Pongwai

The Thai Journal of Pharmaceutical Sciences

A two-level full factorial experimental design was applied to study the influences of various tabletting process variables on the properties of hydrochorothiazide (HCTZ) tablets prepared by direct compression and wet granulation. Sixteen HCTZ tablet form...


The State Of The Thai National Drug Policy : An Indicator Analysis, Sauwakon Ratanawijitrasin, Pompis Silkavute Jan 1997

The State Of The Thai National Drug Policy : An Indicator Analysis, Sauwakon Ratanawijitrasin, Pompis Silkavute

The Thai Journal of Pharmaceutical Sciences

This paper reports key concepts and findings of an indicator study of the Thai National Drug Policy. This study is a part of the “Comparative Analysis of National Drug Policies” Project, which was carried out in 12 countries. Eighty-three standardize...


Physical Properties And Release Characteristics Of Matrices Prepared From Co-Spray Dried Powders Of Propranolol Hydrochloride And Chitosan, Poj Kulvanich, Sasitom Prugmahachaikul, Krisana Kraisintu Jan 1997

Physical Properties And Release Characteristics Of Matrices Prepared From Co-Spray Dried Powders Of Propranolol Hydrochloride And Chitosan, Poj Kulvanich, Sasitom Prugmahachaikul, Krisana Kraisintu

The Thai Journal of Pharmaceutical Sciences

Chitosan was prepared by deacetylation of chitin from shrimp hulls at various reaction times to yield chitosans having different degrees of deacetylation. Chitosans obtained were employed to prepare co-spray dried powders of propranolol hydrochloride-chi...


Xerostomia And Management(โรคน้ำลายแห้งและการดูแลรักษา), Chantana Aromdee Jan 1997

Xerostomia And Management(โรคน้ำลายแห้งและการดูแลรักษา), Chantana Aromdee

The Thai Journal of Pharmaceutical Sciences

Xerostomia is a dried mouth symptom caused by salivary gland dysfunction. The major causes are inflammation or atrophy of the salivary glands, side effects of some drugs or some psychological factors. The inflammation or atrophy of salivary glands is usu...