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Articles 3181 - 3210 of 5793
Full-Text Articles in Neuroscience and Neurobiology
Non-Canonical Activation Of Creb/Crh-1 Mediates Neuroprotection In A Caenorhabditis Elegans Model Of Excitotoxic Necrosis, K. Genevieve Feldmann
Non-Canonical Activation Of Creb/Crh-1 Mediates Neuroprotection In A Caenorhabditis Elegans Model Of Excitotoxic Necrosis, K. Genevieve Feldmann
Dissertations, Theses, and Capstone Projects
Excitotoxicity, which is a major cause of neurodegeneration in brain ischemia, can also activate neuroprotective pathways. A frequently suggested neuroprotective cascade involves the activation of the transcription factor CREB by its phosphorylation, but on its own this mode of CREB activation is promiscuous. We aim to elucidate the specific mechanism of CREB activation in excitotoxicity-induced neuroprotection, focusing on three suggested models: CREB phosphorylation by calcium-activated kinases in the cytoplasm or nucleus, and the activation of CREB by CRTC (an important cofactor). Using a C. elegans model of excitotoxicity, we demonstrate that CREB’s neuroprotective effect is mainly seen in neurons exposed …
Event-Related Potential Studies Of Error Monitoring To Affective And Non-Affective Stimuli In Adolescents And Emerging Adults, Rebecca K. Reed
Event-Related Potential Studies Of Error Monitoring To Affective And Non-Affective Stimuli In Adolescents And Emerging Adults, Rebecca K. Reed
Dissertations, Theses, and Capstone Projects
It is hypothesized that prefrontal cortex (PFC) and anterior cingulate cortex (ACC) function may be still under development in adolescents. As the generator of the error-related negativity (ERN) and the N2, the ACC is expected to be sensitive to the degree of development with age. In adults, these top-down control areas ideally serve to direct attention to goal-relevant information, which can increase the likelihood of making a correct choice, even in fast-response laboratory based tasks. However, adolescents may show increased susceptibility in these top-down control areas when the stimulus is social and emotional. In the first study, event-related potentials were …
Dementia Gone Viral: How Years Of Research Linking Alzheimer's Disease And Infections Has Been Lost In Translation, Mary Sawyer
Dementia Gone Viral: How Years Of Research Linking Alzheimer's Disease And Infections Has Been Lost In Translation, Mary Sawyer
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Animal Linguistics: How Human Language Developed From Animal Communication, Fritz Josephsen
Animal Linguistics: How Human Language Developed From Animal Communication, Fritz Josephsen
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Understanding Blindsight As A Window To Consciousness, Danielle Wald
Understanding Blindsight As A Window To Consciousness, Danielle Wald
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Let's Get Scent-I-Mental, David Perez
Let's Get Scent-I-Mental, David Perez
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Oxytocin & Vasopressin: How Social Ties Are Formed, Rachel Arens
Oxytocin & Vasopressin: How Social Ties Are Formed, Rachel Arens
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Eureka Zika! How The Feared Virus May Be The Key To Treating Gliobastoma, Samantha Palicz
Eureka Zika! How The Feared Virus May Be The Key To Treating Gliobastoma, Samantha Palicz
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
All Roads Lead To Anxiety: Mental Health In Young Adults With Autism Spectrum Disorders, Nikki Scheman
All Roads Lead To Anxiety: Mental Health In Young Adults With Autism Spectrum Disorders, Nikki Scheman
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Synesthesia: Sometimes, You Really Do Eat Your Words, John Wilhelm
Synesthesia: Sometimes, You Really Do Eat Your Words, John Wilhelm
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Deafness & Language, Yara Al-Nouri
Deafness & Language, Yara Al-Nouri
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Hugs Vs. Drugs: How Zebrafish And The Science Of Social Attachment Can Help Us Understand America's Opioid Epidemic, Eduardo Vargas
Hugs Vs. Drugs: How Zebrafish And The Science Of Social Attachment Can Help Us Understand America's Opioid Epidemic, Eduardo Vargas
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Mushrooms For Improvement: The Case For Psilocybin-Assisted Therapy, Harry Justus
Mushrooms For Improvement: The Case For Psilocybin-Assisted Therapy, Harry Justus
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Parasite Mind Control: How A Single Celled Parasite Carried In The Cat Intestine May Be Quietly Tweaking Our Behavior, Sophie Letcher
Parasite Mind Control: How A Single Celled Parasite Carried In The Cat Intestine May Be Quietly Tweaking Our Behavior, Sophie Letcher
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
News On Nootropics: Is Metacognition Right For You?, Diana Aboubakare
News On Nootropics: Is Metacognition Right For You?, Diana Aboubakare
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
The Curious Question Of Social Synchronization, Jennifer Cabiya
The Curious Question Of Social Synchronization, Jennifer Cabiya
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Scientific Kenyon Neuroscience Edition (Full Issue)
Scientific Kenyon Neuroscience Edition (Full Issue)
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Shifting The Blame: A Closer Look At Eating Disorders, Kelsey Trulik
Shifting The Blame: A Closer Look At Eating Disorders, Kelsey Trulik
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
New Body, Who Dis: Getting Ahead, Dana Oakes
New Body, Who Dis: Getting Ahead, Dana Oakes
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Spinal Cord Injuries: The Life After, Woo Jeon
Spinal Cord Injuries: The Life After, Woo Jeon
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Mindfulness For The Masses, Emma Klug
Mindfulness For The Masses, Emma Klug
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
The Genetics Of Being A Lightweight: Tipsy Genes, Jessica Khrakovski
The Genetics Of Being A Lightweight: Tipsy Genes, Jessica Khrakovski
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Tired Tremors: Parkinson's And Sleep Disturbances, Julia Wilson
Tired Tremors: Parkinson's And Sleep Disturbances, Julia Wilson
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Nothing Tastes As Good As Skinny Feels: Unmasking The Neurobiological Basis Of Anorexia, Louise Yang
Nothing Tastes As Good As Skinny Feels: Unmasking The Neurobiological Basis Of Anorexia, Louise Yang
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Tasting The Rainbow: Perception, Hallucination, Act Of God, Or Just Plain Crazy?, Olivia Depalo
Tasting The Rainbow: Perception, Hallucination, Act Of God, Or Just Plain Crazy?, Olivia Depalo
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
How To Read: A Written Guide, Ben Tauber
How To Read: A Written Guide, Ben Tauber
Scientific Kenyon: The Neuroscience Edition
No abstract provided.
Population Coding And Spectrotemporal Tuning In The Owl’S Optic Tectum, Olivia K. Murray, Roland Ferger, Michael V. Beckert, Keaunu Shadron, José L. Peña
Population Coding And Spectrotemporal Tuning In The Owl’S Optic Tectum, Olivia K. Murray, Roland Ferger, Michael V. Beckert, Keaunu Shadron, José L. Peña
Undergraduate Research Symposium Posters
Barn owls (Tyto furcata) are a model organism to study sound location and provide access to a neural population representing auditory space. They use interaural time differences (ITD) and interaural level differences (ILD) to localize sound. Neurons in the barn owl’s optic tectum (OT), a part of the midbrain, which respond to combinations of these binaural cues, form a neural map of auditory space which supports sound-orienting behavior. Understanding population responses in the auditory system involves identifying the frequency components of acoustic signals which evoke spikes. Together, these frequency components and the time between their occurrence in the stimulus and …
The Effects Of Long-Term Treadmill Exercise Training On Amyloid-Beta Plaque Levels And Behavioral Profile In 15-Month Tg2576 Mice, Riya R. Thomas
The Effects Of Long-Term Treadmill Exercise Training On Amyloid-Beta Plaque Levels And Behavioral Profile In 15-Month Tg2576 Mice, Riya R. Thomas
Graduate Theses/Dissertations
Alzheimer’s disease (AD) is a progressive, neurodegenerative disease that is characterized by progressive loss of memory and cognitive function. The causative factors of this disease include modifications in neuronal cell metabolism, such as the progression of neurotic injury by amyloid beta (Aβ), and tau tangle deposition in the brain. Recent studies show that brain atrophy and other pathologic conditions are responsible for dementia in older individuals (80 years of age or older). Non-pharmacological interventions may have a role in both the prevention and slowing disease progression in AD. The role of exercise training in disease prevention has been evaluated in …
Spinal Cord Trauma: An Overview Of Normal Structure And Function, Primary And Secondary Mechanisms Of Injury, And Emerging Treatment Modalities, Daniel Morin
Senior Honors Theses
The structures of the spinal cord and vertebral column are designed to provide flexibility, while still providing ample protection for the spinal cord deep within. While it does offer remarkable protection against most routine trauma, the spinal cord is still vulnerable to high-force etiologies of trauma and may become damaged as a result. These events are referred to as primary injury. Following the initial injury, the body’s own physiological responses cause a cascade of deleterious effects, known as secondary injury. Secondary injury is a major therapeutic target in mitigating the effects of spinal cord injury (SCI), and much research is …