Life Sciences | Open Access Articles | Digital Commons Network™

Oriented Cell Growth On Self-Assembled Bacteriophage M13 Thin Films, Jianhua Rong, L. Andrew Lee, Kai Li, Brandon Harp, Charlene M. Mello, Zhongwei Niu, Qian Wang

Faculty Publications

Fibrillar M13 bacteriophages were used as basic building blocks to generate thin films with aligned nanogrooves, which, upon chemical grafting with RGD peptides, guide cell alignment and orient the cell outgrowth along defined directions.

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Many Species In One: Dna Barcoding Overestimates The Number Of Species When Nuclear Mitochondrial Pseudogenes Are Coamplified, Michael F. Whiting, Hojun Song, Keith A. Crandall, Jennifer E. Buhay

Faculty Publications

Nuclear mitochondrial pseudogenes (numts) are nonfunctional copies of mtDNA in the nucleus that have been found in major clades of eukaryotic organisms.

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Recruitment Of Coastal Fishes And Oceanographic Variability In Central California, J. R. Wilson, B. R. Broitman, J. E. Caselle, D. E. Wendt

Biological Sciences

Recruitment of pelagic larval fishes to the nearshore environment is dependent on a suite of biological and physical processes operating at many spatial and temporal scales. Nearshore circulation processes associated with coastal upwelling are widely upheld as major determinants of year class strength for many rockfishes (Sebastes spp.), but the mechanism by which these processes drive recruitment is largely unknown. We used Standard Monitoring Units for the Recruitment of Fishes (SMURFs) to monitor recruitment of two rockfish complexes (Sebastes spp.) and cabezon (Scorpaenichthys marmoratus) from March to September of 2004 and 2005 at 3 sites along …

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Syble T. Jones, Syble T. Jones, Institute Of Child Nutrition. Child Nutrition Archives.

Oral History Project (all interviews)

Syble T. Jones is the former Food Service Director for Rapides Parish, Louisiana. When Syble started her career in 1968 she had 27,000 students spread across 54 schools.

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Smokejumper Obituary: Wahlstrom, Calvin "Gene" (Pilot 0000), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

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Segmenting Brain Tumors Using Pseudo-Conditional Random Fields, Chi-Hoon Lee, Shaojun Wang, Albert Murtha, Matthew R.G. Brown, Russell Greiner

Kno.e.sis Publications

Locating Brain tumor segmentation within MR (magnetic resonance) images is integral to the treatment of brain cancer. This segmentation task requires classifying each voxel as either tumor or non-tumor, based on a description of that voxel. Unfortunately, standard classifiers, such as Logistic Regression (LR) and Support Vector Machines (SVM), typically have limited accuracy as they treat voxels as independent and identically distributed (iid). Approaches based on random fields, which are able to incorporate spatial constraints, have recently been applied to brain tumor segmentation with notable performance improvement over iid classifiers. However, previous random field systems involved computationally intractable …

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Smokejumper Obituary: Zediker, Richard (Redmond 1964), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

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Protecting Sorghum Grain From Pests In Africa, Intsormil

INTSORMIL Impacts and Bulletins

Insect pests destroy more than 35% of stored grain worldwide and probably even more in Africa. Considering the current global food shortage this is a tremendous loss. To mitigate losses caused by insects in stored sorghum grain, INTSORMIL scientist Bonnie Pendleton of West Texas A&M University is collaborating with African entomologists to develop management strategies. Storage conditions are critical in preventing losses due to pests. A survey in Mali by IER scientist Niamoye Yaro Diarisso found that farmers in the Koulikoro and Ségou regions thresh sorghum and millet and store it in the form of grain. However, in the Sikasso …

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The Bile Response Repressor Brer Regulates Expression Of The Vibrio Cholerae Breab Efflux System Operon, Francisca A. Cerda-Maira, Carol S. Ringelberg, Ronald K. Taylor

Dartmouth Scholarship

Enteric pathogens have developed several resistance mechanisms to survive the antimicrobial action of bile. We investigated the transcriptional profile of Vibrio cholerae O1 El Tor strain C6706 under virulence gene-inducing conditions in the presence and absence of bile. Microarray analysis revealed that the expression of 119 genes was affected by bile. The mRNA levels of genes encoding proteins involved in transport were increased in the presence of bile, whereas the mRNA levels of genes encoding proteins involved in pathogenesis and chemotaxis were decreased. This study identified genes encoding transcriptional regulators from the TetR family (vexR and breR) and …

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Warren County, Kentucky Garden Club - Scrapbook, 1933-1956 (Sc 1740), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid only for Manuscripts Small Collection 1740. Scrapbook compiled by Ethel Alma Folllin containing minutes, news clippings, programs, etc. related to the activities of the Warren County Garden Club and its members.

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Caspase-Cleaved Tar Dna Binding Protein-43 Is A Major Pathological Finding In Alzheimer’S Disease, Troy T. Rohn

Biology Faculty Publications and Presentations

The TAR DNA binding protein-43 (TDP-43) has been identified as a major constituent of inclusions found in frontotemporal dementia with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis (ALS). To determine a possible role for TDP-43 in Alzheimer’s disease (AD), a site-directed caspase-cleavage antibody to TDP-43 based upon a known caspase-3 cleavage consensus site within TDP-43 at position D219 was designed. In vitro, this antibody labeled the predicted 25 kDa caspase-cleavage fragment of TDP-43 without labeling full-length TDP-43 following digestion of recombinant TDP-43 with caspase-3 or treatment of Hela cells with staurosporine. Application of this antibody in postmortem brain sections …

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Resulting Shifts In Percentile And Standard Placements After Comparison Of The Bod Pod And Dxa, Timothy Heden†, Steven Shepard†, John Smith‡, Kay Covington‡, James Lecheminant‡

International Journal of Exercise Science

The purpose of this study was to determine the validity of the BOD POD® when compared to the DXA and if placement on a percentile chart and standard table is affected by any differences between the two measures. A total of 244 (27.7 ± 10.8 yrs, 77.3 ± 16.1 kg, 171.4 ± 10.1 cm, 26.31 ± 5.42 BMI) males and females between the ages of 18 and 52 were recruited to participate in this study. The participant’s body fat percentage (%BF) was tested in random order on the BOD POD® and DXA during a 30-minute session following manufacturer’s guidelines and …

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Intsormil And Iiam Collaborate To Promote Sorghum Production In Mozambique, Intsormil

INTSORMIL Impacts and Bulletins

Sorghum is a major cereal grain in Mozambique with a cultivated area of 2.7 million hectares. It is considered as a food security crop in most of the provinces in the country, especially in regions where rainfall is a limiting factor for maize and rice production. However, due to a lack of seed and poor distribution of improved sorghums farmers continue to use their local varieties which have low productivity potential (0.2 - 0.6 ton/ha). To increase productivity and provide food security there is an urgent need for (1) the development of varieties with higher yield potential, (2) improved crop …

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Statins Induce Apoptosis In Ovarian Cancer Cells Through Activation Of Jnk And Enhancement Of Bim Expression, Hongli Liu, Shu-Ling Liang, Sheetal Kumar, Crystal M. Weyman, Wendy Liu, Aimin Zhou

Biological, Geological, and Environmental Faculty Publications

Ovarian cancer is the leading cause of death among all gynecological malignancies in Western countries. Although therapy for ovarian cancer has been greatly improved in the past 20 years, the overall survival for patients with advanced ovarian cancer has not changed signiWcantly. The poor survival rates in patients with advanced ovarian cancer are due both to late diagnosis and to lack of eVective drugs for the majority of patients who have a relapse and develop resistance to current chemotherapy agents used for ovarian cancer. Thus, developing and discovering eVective novel drugs with diVerent molecular structures from conventional chemotherapy agents have …

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Resulting Shifts In Percentile And Standard Placements After Comparison Of The Bod Pod And Dxa, Timothy Heden, Steve Shepard, John Smith, Kay Covington, James D. Lecheminant

Faculty Publications

Int J Exerc Sci 1(3) : 113-124, 2008. The purpose of this study was to determine the validity of the BOD POD® when compared to the DXA and if placement on a percentile chart and standard table is affected by any differences between the two measures. A total of 244 (27.7 ± 10.8 yrs, 77.3 ± 16.1 kg, 171.4 ± 10.1 cm, 26.31 ± 5.42 BMI) males and females between the ages of 18 and 52 were recruited to participate in this study. The participant’s body fat percentage (%BF) was tested in random order on the BOD POD® and DXA …

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Application Of Shortest-Path Network Analysis To Identify Genes That Modulate Longevity In Saccharomyces Cerevisiae, Jr Managbanag

Theses and Dissertations

Shortest-path network analysis was employed to identify novel genes that modulate longevity in the baker’s yeast Saccharomyces cerevisiae. Based upon a set of previously reported genes associated with increased life span, a shortest path network algorithm was applied to a pre-existing protein-protein interaction dataset in order to construct a shortest-path longevity network. To validate this network, the replicative aging potential of 88 single gene deletion strains corresponding to predicted components of the shortest path longevity network was determined. The 88 single-gene deletion strains identified by a network approach are significantly enriched for mutation conferring both increased and decreased replicative life …

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Differential Loss Of Embryonic Globin Genes During The Radiation Of Placental Mammals, Juan C. Opazo, Federico Hoffmann, Jay F. Storz

Jay F. Storz Publications

The differential gain and loss of genes from homologous gene families represents an important source of functional variation among the genomes of different species. Differences in gene content between species are primarily attributable to lineage-specific gene gains via duplication and lineage-specific losses via deletion or inactivation. Here, we use a comparative genomic approach to investigate this process of gene turnover in the β-globin gene family of placental mammals. By analyzing genomic sequence data from representatives of each of the main superordinal clades of placental mammals, we were able to reconstruct pathways of gene family evolution during the basal radiation of …

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Inhibitors Of Plant Peptide Deformylase For Use As Broad-Spectrum Herbicides And Methods For Identifying The Same, Robert L. Houtz, Lynnette M. A. Dirk, Mark Alan Wiliams

Horticulture Faculty Patents

The invention relates to a method of identifying herbicides and to the use of inhibitors of plant peptide deformylase as broad spectrum herbicides.

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Breakdown And Invertebrate Colonization Of Dead Wood In Wetland, Upland, And River Habitats, Amy Braccia, Darold P. Batzer

Biological Sciences Faculty and Staff Research

Breakdown of woody debris in river and upland habitats as well as the interactions between wood and invertebrates have been well described. Studies of wood in wetlands are rare, and far less is known about breakdown and invertebrate use of wood in these transitional habitats. This study experimentally assessed breakdown and invertebrate colonization of wood in a floodplain wetland and directly related patterns in the wetland to adjacent river and upland habitats. Over a 2.7 year period, we monitored breakdown and invertebrate presence in 10 cm diameter × 150 cm long sweetgum (Liquidambar styraciflua L.) logs in a floodplain wetland …

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Use Of An Alpha-Smooth Muscle Actin (Smaa) Gfp Reporter To Identify An Osteoprogenitor Population, Zana Kalajzic, Haitao Li, Li-Ping Wang, Xi Jiang, Katie B. Lamothe, Douglas J. Adams, Hector L. Aguila, David W. Rowe, Ivo Kalajzic

UCHC Articles - Research

Identification of a reliable marker of skeletal precursor cells within calcified and soft tissues remains a major challenge for the field. To address this, we used a transgenic model in which osteoblasts can be eliminated by pharmacological treatment. Following osteoblast ablation a dramatic increase in a population of α-smooth muscle actin (α-SMA) positive cells was observed. During early recovery phase from ablation we have detected cells with the simultaneous expression of SMAA and a preosteoblastic 3.6GFP marker, indicating the potential for transition of α-SMA⁺ cells towards osteoprogenitor lineage. Utilizing α-SMAGFP transgene, α-SMAGFP⁺ positive cells were detected in the …

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A Crucial Role In Cell Spreading For The Interaction Of Abl Pxxp Motifs With Crk And Nck Adaptors, Susumu Antoku, Gonzalo M. Rivera, Bruce J. Mayer

UCHC Articles - Research

The dynamic reorganization of actin structures helps to mediate the interaction of cells with their environment. The Abl non-receptor tyrosine kinase can modulate actin rearrangement during cell attachment. Here we report that the Abl PxxP motifs, which bind Src homology 3 (SH3) domains, are indispensable for the coordinated regulation of filopodium and focal adhesion formation and cell-spreading dynamics during attachment. Candidate Abl PxxP-motif-binding partners were identified by screening a comprehensive SH3-domain phage-display library. A combination of protein overexpression, silencing, pharmacological manipulation and mutational analysis demonstrated that the PxxP motifs of Abl exert their effects on actin organization by two distinct …

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Pollen From Western Australia At A Glance, Rob Manning

Bulletins 4000 -

Western Australian pollen proteins are high compared to many other plant species. Banksia pollens are highest at greater than 30% followed by eucalypt and acacia, which range from 20-28%.

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Critical Review Of The Literature On Marine Mammal Population Modelling, Edward O. Keith

Marine & Environmental Sciences Faculty Reports

A comprehensive literature review and modeling effort have been conducted in order to determine which vital rates are most important to determining the growth and sustainability of marine mammal populations. Also addressed are the impacts of life-history, ecological, and genetic variation on vital rates and population sustainability and how much each vital parameter can change before a change in population trend would be expected. Additionally, the influence of ecological energetics and foraging strategies on vital rates and their limits of sustainable change are examined, and the nature of how an increase in sound in the marine environment might influence marine …

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Population Structure Of Coyote (Canis Latrans) In The Urban Landscape Of The Cleveland, Ohio Area, Rebecca M. Rashleigh, Robert A. Krebs, Harry Van Keulen

Biological, Geological, and Environmental Faculty Publications

To obtain information on the population structure of coyote (Canis latrans) in an urban setting, a non-invasive genetic sampling technique was applied that consisted of DNA isolation from scat collected around the Cleveland metropolitan area. Muscle tissue was provided from two other coyotes. Amplifying the mitochondrial D-loop or control region produced 33 haplotypes from just 57 coyote sequences and two additional dog sequences from putative coyote-dog hybrids. The mitochondrial DNA genetic diversity in the Cleveland area was high, π 0.02, and composed of six distinct haplotype lineages. In addition, Fst values ranged from 0.07 between collections east and west of …

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Communicator, Sept. 2008, San Jose State University, Department Of Kinesiology

Communicator (Kinesiology)

Volume 21, Issue 1

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A New Species Of Cecidomyia (Diptera: Cecidomyiidae) Feeding On Resin Of Baldcypress, Raymond Gagne, Kenneth Hibbard

USDA Systematic Entomology Laboratory

Cecidomyia lamellate Gagné, new species, is described from adults of both sexes, pupae, and larvae taken from resin in branchlet swellings of baldcypress, Taxodium distichum (L.) Rich. (Taxodiaceae), in Fort Pierce, Florida. Some anatomical characters of the new species depart from the previously known limits of the genus. Baldcypress is the first known non- Pinaceae host of Cecidomyia.

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Full-Text Articles in Life Sciences

Oriented Cell Growth On Self-Assembled Bacteriophage M13 Thin Films, Jianhua Rong, L. Andrew Lee, Kai Li, Brandon Harp, Charlene M. Mello, Zhongwei Niu, Qian Wang

Faculty Publications

Many Species In One: Dna Barcoding Overestimates The Number Of Species When Nuclear Mitochondrial Pseudogenes Are Coamplified, Michael F. Whiting, Hojun Song, Keith A. Crandall, Jennifer E. Buhay

Faculty Publications

Recruitment Of Coastal Fishes And Oceanographic Variability In Central California, J. R. Wilson, B. R. Broitman, J. E. Caselle, D. E. Wendt

Biological Sciences

Syble T. Jones, Syble T. Jones, Institute Of Child Nutrition. Child Nutrition Archives.

Oral History Project (all interviews)

Smokejumper Obituary: Wahlstrom, Calvin "Gene" (Pilot 0000), National Smokejumper Association

Smokejumper Obituaries

Segmenting Brain Tumors Using Pseudo-Conditional Random Fields, Chi-Hoon Lee, Shaojun Wang, Albert Murtha, Matthew R.G. Brown, Russell Greiner

Kno.e.sis Publications

Smokejumper Obituary: Zediker, Richard (Redmond 1964), National Smokejumper Association

Smokejumper Obituaries

Protecting Sorghum Grain From Pests In Africa, Intsormil

INTSORMIL Impacts and Bulletins

The Bile Response Repressor Brer Regulates Expression Of The Vibrio Cholerae Breab Efflux System Operon, Francisca A. Cerda-Maira, Carol S. Ringelberg, Ronald K. Taylor

Dartmouth Scholarship

Warren County, Kentucky Garden Club - Scrapbook, 1933-1956 (Sc 1740), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Caspase-Cleaved Tar Dna Binding Protein-43 Is A Major Pathological Finding In Alzheimer’S Disease, Troy T. Rohn

Biology Faculty Publications and Presentations

Resulting Shifts In Percentile And Standard Placements After Comparison Of The Bod Pod And Dxa, Timothy Heden†, Steven Shepard†, John Smith‡, Kay Covington‡, James Lecheminant‡

International Journal of Exercise Science

Intsormil And Iiam Collaborate To Promote Sorghum Production In Mozambique, Intsormil

INTSORMIL Impacts and Bulletins

Statins Induce Apoptosis In Ovarian Cancer Cells Through Activation Of Jnk And Enhancement Of Bim Expression, Hongli Liu, Shu-Ling Liang, Sheetal Kumar, Crystal M. Weyman, Wendy Liu, Aimin Zhou

Biological, Geological, and Environmental Faculty Publications

Resulting Shifts In Percentile And Standard Placements After Comparison Of The Bod Pod And Dxa, Timothy Heden, Steve Shepard, John Smith, Kay Covington, James D. Lecheminant

Faculty Publications

Application Of Shortest-Path Network Analysis To Identify Genes That Modulate Longevity In Saccharomyces Cerevisiae, Jr Managbanag

Theses and Dissertations

Differential Loss Of Embryonic Globin Genes During The Radiation Of Placental Mammals, Juan C. Opazo, Federico Hoffmann, Jay F. Storz

Jay F. Storz Publications

Inhibitors Of Plant Peptide Deformylase For Use As Broad-Spectrum Herbicides And Methods For Identifying The Same, Robert L. Houtz, Lynnette M. A. Dirk, Mark Alan Wiliams

Horticulture Faculty Patents

Breakdown And Invertebrate Colonization Of Dead Wood In Wetland, Upland, And River Habitats, Amy Braccia, Darold P. Batzer

Biological Sciences Faculty and Staff Research

Use Of An Alpha-Smooth Muscle Actin (Smaa) Gfp Reporter To Identify An Osteoprogenitor Population, Zana Kalajzic, Haitao Li, Li-Ping Wang, Xi Jiang, Katie B. Lamothe, Douglas J. Adams, Hector L. Aguila, David W. Rowe, Ivo Kalajzic

UCHC Articles - Research

A Crucial Role In Cell Spreading For The Interaction Of Abl Pxxp Motifs With Crk And Nck Adaptors, Susumu Antoku, Gonzalo M. Rivera, Bruce J. Mayer

UCHC Articles - Research

Pollen From Western Australia At A Glance, Rob Manning

Bulletins 4000 -

Critical Review Of The Literature On Marine Mammal Population Modelling, Edward O. Keith

Marine & Environmental Sciences Faculty Reports

Population Structure Of Coyote (Canis Latrans) In The Urban Landscape Of The Cleveland, Ohio Area, Rebecca M. Rashleigh, Robert A. Krebs, Harry Van Keulen

Biological, Geological, and Environmental Faculty Publications

Communicator, Sept. 2008, San Jose State University, Department Of Kinesiology

Communicator (Kinesiology)

A New Species Of Cecidomyia (Diptera: Cecidomyiidae) Feeding On Resin Of Baldcypress, Raymond Gagne, Kenneth Hibbard

USDA Systematic Entomology Laboratory

Prevalence And Antimicrobial Resistance Of Pathogenic Bacteria In Chicken And Guinea Fowl, Agnes Kilonzo-Nthenge, Samuel N. Nahashon, Fur-Chi Chen, Nathaniel Adefope

Agricultural and Environmental Sciences Faculty Research

Synergistic Applications Of Autonomous Underwater Vehicles And Regional Ocean Modeling System In Coastal Ocean Forecasting, Yi Chao, Zhijin Li, John D. Farrara, Mark A. Moline, Oscar M.E. Schofield, Sharanya J. Majumdar

Biological Sciences

A Faceted Classification Based Approach To Search And Rank Web Apis, Karthik Gomadam, Ajith Harshana Ranabahu, Meenakshi Nagarajan, Amit P. Sheth, Kunal Verma

Kno.e.sis Publications

An Assessment Of The Role Of Chimpanzees In Aids Vaccine Research, Jarrod Bailey

Laboratory Experiments Collection