Life Sciences Commons^™

Max Kämper’S Introduction To The New World, Stanley D. Sides, M.D.

Mammoth Cave Research Symposia

Twenty-seven year old engineer Max Eduard Kämper arrived in America at 4:00 pm on May 16, 1907 and was greeted by a thunderstorm. His presumed goals were to study American manufacturing methods, learn English, and enrich himself musically. New York had so many German immigrants at the time that German was the second most common language spoken in the city. He stayed at the Belvedere House at the corner of 4th Avenue and 18th Street, and the next day visited acquaintances in Newark. He visited New York landmarks and May 20 visited the famed Hippodrome theater. He moved on May …

Searching For Max: The Engineer, The War And The World´S Longest Cave (Part 1), Bernd Kliebhan

Mammoth Cave Research Symposia

In 1908 the German engineer Max Kämper mapped 35 miles of Mammoth Cave, KY. The “Kämper Map,” forgotten in the archives for half a century, is nowadays considered as a masterpiece of underground cartography. Little was known about Max Kämper despite several attempts of American speleo-historians. Most traces were wiped out in two world wars. Nevertheless the authors could find out details of the biography of Max Kämper in German archives. The text is based based upon the radio story “Suche nach Max,” broadcasted by Hessischer Rundfunk - hr1 December 26, 1999, audio download available on http://www.kliebhan.de/kaemper.htm

Mammoth Cave International Center For Science And Learning, Rick Toomey, Shannon R. Trimboli, Bob Ward, Mike Adams, Blaine Ferrell

Mammoth Cave Research Symposia

The Mammoth Cave International Center for Science and Learning (MCICSL) is a cooperative venture of Mammoth Cave National Park and Western Kentucky University. Funding, logistical support, and governance of MCICSL are shared equally by both entities. MCICSL is part of a national network of research learning centers located within the National Park Service.

The goals of MCICSL and the other research learning centers are to:

I. Facilitate the use of parks for scientific inquiry.

II. Support science-informed decision making.

III. Communicate the relevance of and provide access to knowledge gained through scientific research.

IV. Promote science literacy and resource stewardship. …

The Lamps That Lit Their Way, Rick Olson

Mammoth Cave Research Symposia

The distinctive lanterns used at Mammoth Cave from the middle 1800s until 1938 appear to be a locally derived design. Early whale oil railroad lanterns share some characteristics of the Mammoth Cave lanterns, but L&N Railroad lanterns do not appear to have influenced the design. At this time, the design pathway appears to lead from simple open-flame tin candle lanterns to the same lantern with a petticoat lamp affixed in place of the candle, and then finally to the font or oil container being soldered onto the lamp base as one unit. This basic Mammoth Cave lantern varied somewhat over …

A Long History Of Linkages And Synergy: Western Kentucky University And The Mammoth Cave System, Deana Groves, Chris Groves, Weldon Hawkins

Mammoth Cave Research Symposia

No abstract provided.

The Puzzling Mr. Janin And Mammoth Cave Management, 1900-1910, Katie Algeo

Mammoth Cave Research Symposia

Albert Covington Janin was the key architect of tourism development at Mammoth Cave for two decades at the start of the twentieth century, yet little has been written about his tenure. This paper explores his background and accomplishments for the period 1900 to 1910 as an initial attempt to understand his contributions to Mammoth Cave. Material about his activities in relation to Mammoth Cave is synthesized from primary sources in the archival collections of the Huntington Library (HL) of San Marino, California, and the Historical Society of Washington, DC (HSW).

Contributions To Karst Science And Education From The Mammoth Cave Region, Chris Groves, William B. White

Mammoth Cave Research Symposia

No abstract provided.

Mammoth Cave: What A Difference A Few Friends Can Make, Lajuana S. Wilcher

Mammoth Cave Research Symposia

No abstract provided.

Mapping Of Mammoth Cave: How Cartography Fueled Discoveries, With Emphasis On Max Kaemper’S 1908 Map, Roger W. Brucker

Mammoth Cave Research Symposia

Maps came first at Mammoth Cave, Kentucky. Then came explorers who used the maps to make discoveries as they gained a more comprehensive understanding of the longest cave in the world. The saga of mapping at Mammoth Cave parallels the mapping of North America from the 1600s onward. The first map was an “Eye-Draught Map of Mammoth Cave”, penned from memory in 1811, not a survey, to acquaint merchants with the location of saltpeter dirt. In 1835 the managers of Mammoth Cave hired a surveyor, Edmond Lee, to survey and map and profile the main cave passages. Stephen Bishop, a …

Max Kaemper’S Unique Selection Of Place Names For His 1908 Map Of Mammoth Cave, Charles A. Swedlund, George M. Crothers

Mammoth Cave Research Symposia

In this paper we present Max Kaemper’s unique selection of Place Names for his 1908 map of Mammoth Cave. He realized the importance of Place Names and they became a feature on his map. His sensitive selection of Place Names provides a greater cultural emphasis, when compared to the previous maps.

The Evolution Of Cave Mapping And Cartography, Pat Kambesis

Mammoth Cave Research Symposia

“Does it go?” Is the initial question that has inspired many a cave explorer to push the extent of a cave system. But the answer only brings more questions…how far, how long, how deep does it go? During the exploration process, as a cave system reveals its complexity, the questions also change – what is the cave’s relationship to the surface, and to surrounding caves? What are the features and obstacles that the cave contains? Those involved in cave exploration know that the only way to answer these questions is with systematic documentation in the form of cave and surface …

Mammoth Cave National Park's Max Kaemper Centennial Symposium & 9th Science Symposium: Cultural History And Research, Shannon Trimboli , Editor

Mammoth Cave Research Symposia

No abstract provided.

The Importance Of Physiological Limits In Determining Biogeographical Range Shifts Due To Global Climate Change: The Heat-Shock Response, Lars Tomanek

Biological Sciences

Physiological processes that set an organism’s thermal limits are in part determining recent shifts in biogeographic distribution ranges due to global climate change. Several characteristics of the heat-shock response (HSR), such as the onset, maximal, and upper limit of heat-shock protein (Hsp) synthesis, contribute to setting the acute upper thermal limits of most organisms. Aquatic animals from stable, moderately variable, or highly variable thermal environments differ in their HSR. Some animals living in extremely stable thermal environments lack the response altogether. In contrast, rocky intertidal animals that experience highly variable thermal conditions start synthesizing Hsps, that is, the onset of …

Body Mass Index And Health Related Quality Of Life In Elementary School Children: A Pilot Study, Lei Zhang, Peter J. Fos, William D. Johnson, Vafa Kamali, Reagan G. Cox, Miguel A. Zuniga, Theresa Kittle

Faculty Publications

Background: We investigated the relationship between Body Mass Index (BMI) and health-related quality of life (HRQOL) indicated by baseline health status in elementary school children. Methods: Data were obtained via parents whose children enrolled in an elementary school, kindergarten to fourth grade, in southern Mississippi in spring 2004. Parents completed the SF-10 for Children (TM), a brief 10-item questionnaire designed to measure children's HRQOL on a voluntary basis. Results: A total of 279 parents completed the questionnaires for their children. On average, physical and psychosocial summary scores, major indicators for HRQOL, were significantly higher among the elementary school children in …

Recognition Of The Activated States Of Galpha13 By The Rgrgs Domain Of Pdzrhogef, Zhe Chen, William D. Singer, Shahab M. Danesh, Paul C. Sternweis, Stephen R. Sprang

Biological Sciences Faculty Publications

G12 class heterotrimeric G proteins stimulate RhoA activation by RGS-RhoGEFs. However, p115RhoGEF is a GTPase Activating Protein (GAP) toward Galpha13, whereas PDZRhoGEF is not. We have characterized the interaction between the PDZRhoGEF rgRGS domain (PRG-rgRGS) and the alpha subunit of G13 and have determined crystal structures of their complexes in both the inactive state bound to GDP and the active states bound to GDP*AlF (transition state) and GTPgammaS (Michaelis complex). PRG-rgRGS interacts extensively with the helical domain and the effector-binding sites on Galpha13 through contacts that are largely conserved in all three nucleotide-bound states, although PRG-rgRGS has highest affinity to …

Estrogen Receptors In The Medial Amygdala Inhibit The Expression Of Male Prosocial Behavior, Bruce S. Cushing, Adam Perry, Sergei Musatov, Sonoko Ogawa

Biology Faculty Research

Studies using estrogen receptor alpha(ER) knock-out mice indicate that ER alpha masculinizes male behavior. Recent studies of ER alpha and male prosocial behavior have shown an inverse relationship between ER alpha expression in regions of the brain that regulate social behavior, including the medial amygdala (MeA), and the expression of male prosocial behavior. These studies have lead to the hypothesis that low levels of ER alpha are necessary to "permit" the expression of high levels of male prosocial behavior. To test this, viral vectors were used to enhance ER alpha in male prairie voles (Microtus ochrogaster), which display high levels …

Frequently Asked Questions Rat Island Habitat Restoration Project

United States Fish and Wildlife Service: Publications

A conservation partnership is restoring the native ecosystem of Rat Island in the Alaska Maritime National Wildlife Refuge by eliminating introduced rats. The ecosystem, especially the bird population, was decimated by the introduction of Norway rats via a shipwreck in the 1780’s. There are virtually no seabirds and few other birds left on Rat Island. Successful rat eradication would restore habitat and allow birds to re-colonize the island. The first step in island restoration, applying rodenticide to the island, was completed in early October. Biological monitoring in the summer of 2009 and 2010 will determine if all the rats have …

Avian Dispersal Of The Actinomycete Frankia Across A Barrier Island Landscape, Spencer Bissett

Theses and Dissertations

In the nutrient-poor soils characteristic of coastal environments, symbiotic association with the nitrogen-fixing root endosymbiont Frankia is essential to establishment and survival of the woody shrub Morella cerifera. Nutrient deficiency quickly becomes severe unless seedlings are infected by Frankia soon after germination. However, the means of arrival of Frankia prior to shrub establishment has not been determined. Using sterilized lab-grown M. cerifera seedlings and fecal samples collected from passerine birds on the Eastern Shore of Virginia, viability of avian dispersal of the bacteria was tested. Although passerine fecal samples did produce nodules on some sterilized M. cerifera seedlings, these experimental …

Conservation And Conflict Between Endangered Desert Fishes, Jennifer M. Gumm, Jennifer L. Snekser, Murray Itzkowitz

Faculty Publications

Conservation of naturally sympatric endangered species requires unique considerations. While impacts of invasive species garner much attention, interactions between endangered species must also be managed. The endangered Leon Springs pupfish, Cyprinodon bovinus, has suffered a population decline due to decreasing natural habitat. As breeding habitat is lost, C. bovinus is also adversely affected by the sympatric, endangered Pecos gambusia, Gambusia nobilis. Here, we document interactions between these species, finding significantly more G. nobilis accumulated at pupfish spawning events than randomly distributed on breeding grounds in the absence of spawning. As a known egg predator, our results suggest that G. nobilis …

Development And Annotation Of Perennial Triticeae Ests And Ssr Markers., B.S. Bushman, S R Larson, I W Mott, P F Cliften, R R Wang, N J Chatterton, A G Hernandez, S Ali, R W Kim, Jyothi Thimmapuram, G Gong, L Liu, M A Mikel

Cyber Center Publications

Triticeae contains hundreds of species of both annual and perennial types. Although substantial genomic tools are available for annual Triticeae cereals such as wheat and barley, the perennial Triticeae lack sufficient genomic resources for genetic mapping or diversity research. To increase the amount of sequence information available in the perennial Triticeae, three expressed sequence tag (EST) libraries were developed and annotated for Pseudoroegneria spicata, a mixture of both Elymus wawawaiensis and E. lanceolatus, and a Leymus cinereus x L. triticoides interspecific hybrid. The ESTs were combined into unigene sets of 8 780 unigenes for P. spicata, 11 281 unigenes for …

Simple Inhibitors Of Histone Deacetylase Activity That Combine Features Of Short-Chain Fatty Acid And Hydroxamic Acid Inhibitors, Jessica L. Tischler, Basel Abuaita, Sierra C. Cuthpert, Christopher Fage, Kristi Murphy, Andrew Saxe, Edward B. Furr, Jamie Hedrick, Jennifer Meyers, David Snare, Ali R. Zand

Chemistry & Biochemistry Publications

Butyric acid and trichostatin A (TSA) are anti-cancer compounds that cause the upregulation of genes involved in differentiation and cell cycle regulation by inhibiting histone deacetylase (HDAC) activity. In this study we have synthesized and evaluated compounds that combine the bioavailability of short-chain fatty acids, like butyric acid, with the bidentate binding ability of TSA. A series of analogs were made to examine the effects of chain length, simple aromatic cap groups, and substituted hydroxamates on the compounds' ability to inhibit rat-liver HDAC using a fluorometric assay. In keeping with previous structure-activity relationships, the most effective inhibitors consisted of longer …

Acquisition De Modèles Pour L’Étude De L’Absorption Percutanée Des Substances Chimiques : Cellules De Diffusion À Flux Continu, Claude Viau, Suzanne Leroux, Ross Thuot, Sophie Lim

Rapports de recherche scientifique

Dans les milieux de travail où des substances chimiques sont utilisées, celles-ci peuvent se retrouver dans l’air. Les employés peuvent donc y être exposés par le fait de la respiration. C’est d’ailleurs pour ça que le règlement sur la santé et la sécurité du travail donne des valeurs limites d’exposition dans l’air pour près de 700 substances chimiques. Mais il est aussi possible d’être exposé par le contact des substances avec la peau. Quand on veut savoir à quel point un travailleur peut absorber des substances dans son organisme de cette manière, on doit savoir trois choses principales :

• la …

Traversing Swanton Road, 1st Ed., James A. West

Academic, Government & Associated Organizational Research Resources

Situated at the northwest end of Santa Cruz County and occupying circa 30 square miles of sharply contrasted terrain, the Scott Creek Watershed concentrates within its geomorphological boundaries, at least 10-12% of California's flora, both native and introduced. Paradoxically, the use/abuse that the watershed has sustained over the past 140+ years, has not necessarily diminished the biodiversity and perhaps parallels the naturally disruptive but biologically energizing processes (fire, flooding, landslides and erosion), which have also been historically documented for the area for +60 years. This is an early edition of an extensive document by James A. West. Please visit the …

Effects Of Filtration Temperature And Heat Treatment On Composition And Rheological Properties Of Whole Milk Ultrafiltration Retentates, John W. Montella

Master's Theses

ABSTRACT

Effects of Filtration Temperature and Heat Treatment on Composition and Rheological Properties of Whole Milk Ultrafiltration Retentates

John William Montella

For the first part of my thesis, the effects of filtration temperature and heat treatment on the compositional properties of whole milk Ultrafiltration retentate (UF) were studied. Ultrafiltration is primarily run at temperatures in the range of 50-55°C but more and more plants are starting to filter at refrigeration temperatures. In the ultrafiltration of milk, filtration temperature can affect the composition of the retentate by affecting the chemistry of milk components. The application of a pasteurization step can also …

Familiarity With Breeding Habitat Improves Daily Survival In Colonial Cliff Swallows, Charles R. Brown, Mary Bomberger Brown, Kathleen R. Brazeal

School of Natural Resources: Faculty Publications

One probable cost of dispersing to a new breeding habitat is unfamiliarity with local conditions such as the whereabouts of food or the habits of local predators, and consequently immigrants may have lower probabilities of survival than more experienced residents. Within a breeding season, estimated daily survival probabilities of cliff swallows, Petrochelidon pyrrhonota, at colonies in southwestern Nebraska, USA, were highest for birds that had always nested at the same site, followed by those for birds that had nested there in some (but not all) past years. Daily survival probabilities were lowest for birds that were naive immigrants to …

Coral Reef Restoration And Mitigation In Florida And Beyond, Jocelyn Karazsia, Tom Moore, James Byrne, David S. Gilliam, John Hunt

Marine & Environmental Sciences Faculty Proceedings, Presentations, Speeches, Lectures

No abstract provided.

Multidimensional Self-Efficacy And Affect In Wheelchair Basketball Players, Jeffrey J. Martin

Kinesiology, Health and Sport Studies

In the current study, variables grounded in social cognitive theory with athletes with disabilities were examined. Performance, training, resiliency, and thought control self-efficacy, and positive (PA) and negative (NA) affect were examined with wheelchair basketball athletes (N = 79). Consistent with social cognitive theory, weak to strong significant relationships among the four types of self-efficacy (rs = .22–.78) and among self-efficacy and affect (rs = -.40–.29) were found. Basketball players who were efficacious in their ability to overcome training barriers were also confident in their basketball skills and efficacious in their ability to overcome ruminating distressing thoughts …

Phosphorylation Of P27kip1 Regulates Assembly And Activation Of Cyclin D1-Cdk4, Michelle D. Larrea, Jiyong Liang, Thiago G. Da Silva, Feng Hong, Shan H. Shao, Kathy Han, D. Dumont, Joyce M. Slingerland

Chemistry and Physics Faculty Articles

p27 mediates Cdk2 inhibition and is also found in cyclin D1-Cdk4 complexes. The present data support a role for p27 in the assembly of D-type cyclin-Cdk complexes and indicate that both cyclin D1-Cdk4-p27 assembly and kinase activation are regulated by p27 phosphorylation. Prior work showed that p27 can be phosphorylated by protein kinase B/Akt (PKB/Akt) at T157 and T198. Here we show that PKB activation and the appearance of p27pT157 and p27pT198 precede p27-cyclin D1-Cdk4 assembly in early G₁. PI3K/PKB inhibition rapidly reduced p27pT157 and p27pT198 and dissociated cellular p27-cyclin D1-Cdk4. Mutant p27 allele products lacking phosphorylation at …

Town Of Chester Stormwater Management Project, Nhep Community Technical Assistance Program

PREP Reports & Publications

Great Bay Environmental Consulting (GBEC) worked with the Town of Chester Planning Board to improve regulatory approaches to stormwater management. The project was conducted in two phases: Phase I involved an inventory and assessment of existing regulations for their treatment of stormwater management, with recommendations for an approach to improve stormwater management in the town. The Planning Board opted to focus on specific changes to existing subdivision and site planning regulations, so Phase II of the project involved the development of specific recommendations for those regulations.

Portsmouth Vernal Pool Inventory, West Environmental Inc.

PREP Reports & Publications

West Environmental, Inc. (WEI) conducted a city-wide Vernal Pool Inventory to locate, document and map vernal pools in Portsmouth. This effort was coordinated with the Portsmouth Planning Department and Conservation Commission to help the City of Portsmouth in vernal pool identification and mapping. The goal of this project was to locate isolated wetlands that provide vernal pool habitat. Currently the City of Portsmouth’s wetland regulations exempt wetlands less than 5,000 square feet from the local 100’ buffer zone. This study identified smaller wetlands which have the potential to provide vernal pool habitat that may deserve the 100 foot buffer protection. …