Engineering Commons^™

Tra-1-60-Positive/Cd45low Cells Found In The Peripheral Blood Of Prostate Cancer Patients With Metastatic Disease – A Proof-Of-Concept Study, Claudia Schäfer, Yawen Ju, Youngbin Tak, Cesar Vazquez, Sangyoon J. Han, Edwin Tan, Et Al.

Michigan Tech Publications, Part 1

Purpose

Over 90% of all cancer related deaths are due to metastasis. However, current diagnostic tools can't reliably discriminate between invasive and localized cancers.

Patients and methods

In this proof-of-concept study, we employed the embryonic stem cell marker TRA-1-60 (TRA+) to identify TRA + cells within the blood of prostate cancer patients and searched for TRA + cells in men with metastatic and localized cancers. We isolated whole peripheral blood mononuclear cells from 26 metastatic prostate cancer patients, from 13 patients with localized prostate cancer and from 17 healthy controls. Cells were stained for DAPI, CD45 and TRA + by …

Noble-Transition Alloy Absorbers For Near-Infrared Hot-Carrier Optoelectronics, Sara Karoline Figueiredo Stofela

LSU Doctoral Dissertations

Optoelectronics is the field of technology concerned with the study and application of electronic devices that source, detect and control light. Here we focus on the optical communications field which relies on optical fiber systems to carry signals to their destinations operating in the near-infrared range. To improve the performance of current optical fiber systems, one of the paths is to develop better near-infrared photodetectors.

The current group of materials used for near-infrared photodetection relies in the III-V semiconductor family. Although their spectral photosensitivity correlates well with the near-infrared, response time performance and electronic circuit integration remain limited for this …

"When The Enemy Drew Our Attention": Reconsidering Prior Restraint In The Context Of Dual Use Research Of Concern, Caine Caverly

William & Mary Bill of Rights Journal

Through 2016 and 2017, a team led by Canadian virologist David Evans, and funded by an American pharmaceutical company, attempted to synthesize the previously extinct horsepox virus. After just six months and an expenditure of $100,000, the research team was able to successfully construct the virus “using only commercially available information, technology and tools.” In January of 2018, the team went on to publish their information in an American-based journal, PLOS ONE.

The publication was controversial because it included a potential “blueprint” for the synthesis of a genetic strand in the same viral family as the highly lethal, albeit eradicated, …

Frequency-Selective Metasurface Integrated Uncooled Microbolometers, Mahmoud Almasri, Edward C. Kinzel

Mechanical and Aerospace Engineering Faculty Research & Creative Works

A metasurface integrated microbolometer having a sensing layer (e.g., SixGeyO1-x-y). The presence of the metasurface provides selectivity with respect to wavelength, polarization and angle-of-incidence. The presence of the metasurface into the microbolometer affects conversion of electromagnetic to thermal energy, thermal response, electrical integration of the microbolometer, and the tradeoff between resistivity and temperature coefficient of resistance, thereby allowing the ability to obtain a sensing with high temperature coefficient of resistance with lower resistivity values than that of films without the metasurface. The presence of the metasurface removes the need for a Fabry-Perot cavity.

Ground And In-Flight Calibration Of The Osiris-Rex Camera Suite, D. R. Golish, C. Drouet D'Aubigny, B. Rizk, D. N. Dellagiustina, P. H. Smith, K. Becker, N. Shultz, T. Stone, M. K. Barker, E. Mazarico, E. Tatsumi, R. W. Gaskell, L. Harrison, C. Merrill, C. Fellows, B. Williams, S. O'Dougherty, Michael Whitely, Jed Hancock, B. E. Clark, C. W. Hergenrother, D. S. Lauretta

Space Dynamics Laboratory Publications

The OSIRIS-REx Camera Suite (OCAMS) onboard the OSIRIS-REx spacecraft is used to study the shape and surface of the mission’s target, asteroid (101955) Bennu, in support of the selection of a sampling site. We present calibration methods and results for the three OCAMS cameras—MapCam, PolyCam, and SamCam—using data from pre-flight and in-flight calibration campaigns. Pre-flight calibrations established a baseline for a variety of camera properties, including bias and dark behavior, flat fields, stray light, and radiometric calibration. In-flight activities updated these calibrations where possible, allowing us to confidently measure Bennu’s surface. Accurate calibration is critical not only for establishing a …

Classifying Seabed Parameters From Normal Incidence Reflections: Model Comparison And Inversion Technique, Megan Frantz

Dissertations and Theses

As of the year 2019, only about five percent of the seafloor has been topologically mapped and classified for type (e.g., sand, silt, gravel). To rapidly survey the seabed from surface ships or underwater vehicles, acoustic remote sensing methods are needed. In this thesis, acoustic measurements and inverse modeling is investigated as a way to classify seabed type based on estimating parameters such as density, sound speed, and interface roughness. The method uses normal incident acoustic measurements that can be made using either a single beam echo sounder or the normal incident beams from a side scan sonar. The inverse …

Retrospective Study Of Fmol Health System Utilization Using Geospatial Information, Deekshith Mandala

LSU Master's Theses

Medicaid Expansion and closing of Emergency Departments (ED) like Earl K. Long, Baton Rouge General Mid-City ED, and Champion Medical Center changed the health care landscape in East Baton Rouge Parish (EBRP). In this research study, a Geographical Information System (GIS) is used to analyze the impact of the expansion of Medicaid and the inauguration of Our Lady of the Lake North Baton Rouge ED (OLOL NBR ED) over the utilization of Franciscan Missionaries of our Lady Health System (FMOLHS) for both emergency and non-emergency health care services. This study is performed across the 58 neighborhoods of EBRP. Overutilization of …

Fate Of Eroding Crude Asphalt And Emulsion In Shallow Marsh Embayments, William Coronel

LSU Master's Theses

Marshes impacted by the Macondo spill continue to erode, releasing crude oil in the form of a soft asphalt or emulsion to adjacent shallow embayments. This process moves highly weathered crude oil from the marsh profile to comparatively high-energy, shallow, open-water systems where geochemical and microbiological conditions may influence additional weathering. Specifically, we hypothesize that the erosion process can accelerate biodegradation by moving crude oil asphalts and emulsions from a low-energy, anoxic environment in the marsh to a higher-energy, oxic environment in these shallow embayments. Sediment samples were taken in summer 2017 and 2018 across transects which bisect the boundary …

Experimental And Computational Tools For Single Cell Analysis In Cancer Diagnostics, Manibarathi Vaithiyanathan

LSU Doctoral Dissertations

Substantial evidence shows that cellular heterogeneity commonly exists within an isogenic or clonal population. Whether in isolation or caused through a combination of the above events, cellular heterogeneity can dramatically influence cellular decision making and cell fate, however, this can be masked by the average response from a population. One approach to solve this issue is to analyze a population at the individual cell level. The goal of this work is to develop high-throughput experimental and computational platforms to screen and quantify single cancer cells for specific intracellular enzyme activities. An interdisciplinary approach was taken to 1) better understand the …

Experimental Evaluation Of How Mineralogy And Microstructure Impact Micro-Geomechanics Of Shale Rocks, Hui Du

LSU Doctoral Dissertations

Shales play an essential role in petroleum exploration and production because they can occur either as unconventional reservoir rocks for hydrocarbon extraction via hydraulic fracturing or as caprocks for conventional reservoirs and subsurface gas/ waste storage. For both extraction and storage applications, the success rate is directly depending on the rigorous candidate selection. Conventional rock characterization techniques normally measure rock properties by seismic/logging at the reservoir scale, and on drilled/outcrop cores at the core scale. However, shales are highly heterogeneous in composition, containing a large number of reactive minerals in micro/nanoscale with significantly different properties. The structural features and properties …

Results Of Model Tray Experiments Of A Sand Pressiometer And Methods For Determining The Deformation Characteristics Of Soils, Khasanov Askar, Nabiyeva Nigora

Problems of Architecture and Construction

In the paper discusses the results of experimental studies of the stress-strain state of the soil around the walls of the borehole under axisymmetric loading. Analytical expressions are given for determining the soil deformation modulus when tested with a sand pressiometer.

Hydrocyclic Affecting Of Flush Fluid On A Stope Back Of Drilling Fluid, Akilov J., Jabbarov М.

Problems of Architecture and Construction

In article influencing of cyclic affectings of flush fluid on a stressed state of rocks of a bottom-hole zone is esteemed at boring oil and gas wells. By numerical experiments it is demonstrated that picking up rational arguments of hydrocyclic affecting of flush fluid.

Lasers And Their Application In Heating Technology, Khalmanov A., Aymatov R., Omonkulov O., Khudaykulov A.

Problems of Architecture and Construction

Heat engineering is one of the common technical subjects that are important for heat engineering, such as heat generation by radiation, light transmission by optical lubricants, and the use of transmitted light energy. Currently, the laser is a powerful light-emitting diet and is based on the radiation generated by the electron transport of a layer of atomic energy.In article, a heat exchanger is considered in the high-temperature region and the laser radiation in heaters exceeds other heat exchange intensities.

On The Formation Of A Computational Model Of Flexible Gently Sloping Shells And Plates Under Repeated Elastoplastic Loading, Abdusattarov A., Abdukadirov F.

Problems of Architecture and Construction

In this article is given the geometric and physical relations for flexible gentle shells, suggests two forms of communication between the deformation of the middle layer and displacements, respectively, the equilibrium equations and the conditions for compatibility of deformation are derived. For a special case, the implementation algorithm and the results of calculating rectangular plates are presented.

Mathematical Calculation On Durability Of Some Constructions In Building, Khusanov B., Fatkhullayev F.

Problems of Architecture and Construction

In article problems on durability of building constructions are investigated. Using the empirical formula for weight of an arch, under the influence of force, and the extremum theory, critical value of gravity is defined. Further for a homogeneous core which one end is fixed by the hinge, and on the second end force, and depending on a building material and a kind of its form is inserted, there is the greatest value of durability.

Development Of Diagram Methods In Calculations Of Reinforced Concrete Structures, Sagatov Bakhodir, Tillayev Mirjalol

Problems of Architecture and Construction

The paper gives short analysis of the practical use of strain diagrams in design of reinforced concrete structures. Basic principles to obtain experimental diagrams under simple static, regime and dynamic loading are given along with the conditions they have to meet. Further developments of the diagram methods of design are noted.

Statistical Analysis Of Thermal Conductivity Of A Mixture Of Foam Polyurethane With Thin Wooden Chips, Makhmudov M.

Problems of Architecture and Construction

The article presents the results of determining in laboratory conditions the coefficient of thermal conductivity of a mixture of polyurethane foam with wood chips and the results of their statistical processing. Based on the results obtained, the calculated values of the thermal conductivity coefficient of the investigated material are recommended, corresponding to operating conditions A and B.

Main Parameters Of Physical Properties Of Saline Soils Along Highways, Zafarov Olmos, Urushboyev Elbek

Problems of Architecture and Construction

This article provides information about the basic parameters of physical properties of the saline soils in roadside of highways, the key and rational indicators which are determined by the experiments and by calculating respectively in the evaluation of soil physical states, the density of solid particles, the basic parameters of density and moisture of the soil in natural condition.

The Desorption Kinetics Of Methane From Nonaqueous Fluids For Enhanced Well Control, James Lee Nielsen Jr.

LSU Master's Theses

The mass transfer of a dissolved gas evolving to return to the gaseous phase from a liquid is governed by many parameters. This process affects the development of an oil and gas well due to the possibility of gas contamination occurring from either an influx entering the wellbore, or drilling through gas-bearing formations. Once this dissolved hydrocarbon gas circulates up the wellbore, it will begin to evolve from solution and poses a potential risk to drilling equipment, the environment, and personnel at a drilling rig. Being able to predict the behavior of gas desorption based on a known set of …

Influence Of Model Grid Size On The Estimation Of Surface Fluxes Using The Two Source Energy Balance Model And Suas Imagery In Vineyards, Ayman Nassar, Alfonso F. Torres-Rua, William Kustas, Hector Nieto, Mac Mckee, Lawrence E. Hipps, David King Stevens, Joseph Alfieri, John Prueger, Maria Mar Alsina, Lynn Mckee, Calvin Coopmans, Luis Sanchez, Nick Dokoozlian

Civil and Environmental Engineering Faculty Publications

Evapotranspiration (ET) is a key variable for hydrology and irrigation water management,with significant importance in drought-stricken regions of the western US. This is particularly true for California, which grows much of the high-value perennial crops in the US. The advent of small Unmanned Aerial System (sUAS) with sensor technology similar to satellite platforms allows for the estimation of high-resolution ET at plant spacing scale for individual fields. However, while multiple efforts have been made to estimate ET from sUAS products, the sensitivity of ET models to different model grid size/resolution in complex canopies, such as vineyards, is still unknown.The variability …

Mechanical And Structural Behavior Of As-Built And Post Treated Ti6al4v Lattice Structures Fabricated By Selective Laser Melting (Slm), Hala Ahmed Salem

Theses and Dissertations

Lattice structure is a type of cellular structures that is composed of repeatable unit cells, each of which is formed of interconnect network of struts. Lattices with different structures are gaining attention for their good mechanical properties for light weight applications. Selective laser melting (SLM), is one of the AM powder-bed fusion fabrication techniques. SLM is widely known for its capability for fabricating complex metallic structures such as lattice structures with high resolution. SLM process influence the microstructure and mechanical properties of fabricated parts. The used processing parameters influence the level of internal porosity within the fabricated parts which directly …

Goodd, A Global Dataset Of More Than 38,000 Georeferenced Dams., Mark Mulligan, Arnout Van Soesbergen, Leonardo Sáenz

Michigan Tech Publications, Part 1

By presenting the most comprehensive GlObal geOreferenced Database of Dams to date containing more than 38,000 dams as well as their associated catchments, we enable new and improved global analyses of the impact of dams on society and environment and the impact of environmental change (for example land use and climate change) on the catchments of dams. This paper presents the development of the global database through systematic digitisation of satellite imagery globally by a small team and highlights the various approaches to bias estimation and to validation of the data. The following datasets are provided (a) raw digitised coordinates …

Meeting The Needs Of The 21st Century Workforce: Nanotechnology Safety Training, Dominick E. Fazarro, Walt Trybula

Online Journal for Workforce Education and Development

Developing an education effort in a completely new field is very difficult at best. The identification of a need for Nano-Safety education was realized and promoted in 2006. It took a combined effort among a number of institutes of higher-education to even raise the awareness of a need for an education effort. Developing a new area requires not only expertise in the field but plans on how to develop the material to be covered, how to present the material, and how to evaluate the results of the program developed. There are many steps required to be successful. The OSHA Susan …

In Vitro Evaluation Of The Influence Of Substrate Mechanics On Matrix-Assisted Human Chondrocyte Transplantation, Yueh-Hsun Kevin Yang, Courtney R. Ogando, Gilda A. Barabino

Publications and Research

Matrix-assisted chondrocyte transplantation (MACT) is of great interest for the treatment of patients with cartilage lesions. However, the roles of the matrix properties in modulating cartilage tissue integration during MACT recovery have not been fully understood. The objective of this study was to uncover the effects of substrate mechanics on the integration of implanted chondrocyte-laden hydrogels with native cartilage tissues. To this end, agarose hydrogels with Young’s moduli ranging from 0.49 kPa (0.5%, w/v) to 23.08 kPa (10%) were prepared and incorporated into an in vitro human cartilage explant model. The hydrogel-cartilage composites were cultivated for up to 12 weeks …

Research On The Strategy Of Adaptive Uvls Based On Rtds Simulation, Zhao Dan, Man Ji, Yunling Ni, Dengxin Liu, Weidong Wang

Journal of System Simulation

Abstract: Aiming at the improvement of the slow and unstable system voltage recovery after the low voltage load shedding load protected by centralized station area, the traditional low voltage load shedding load strategy will be researched. Considering the factors such as the power shortage and the important grade of the load, the power factor of the load to be cut is introduced, and the low load shedding model is established by minimizing the amount of cut load and minimizing the reactive power. The research is transformed into a belt Constrained multi-objective optimization research. The multi- objective particle swarm optimization algorithm …

Design Of Air Defense Missile Weapon System Simulation Platform Based On Xsim Platform, Kaizhi Ruan, Qingqing Yuan, Wenhua Zhai, Zhiqiang Zhang

Journal of System Simulation

Abstract: Taking the system simulation technology which applied to the scheme argumentation, optimization design, flight test forecast, battle effectiveness evaluation of air defense missile weapon system as background, the design method of air defense missile weapon system simulation platform based on Xsim platform was put forward. The total configuration design, model design and simulation process design of the platform were discussed. An simulation platform of an air defense missile weapon system was accomplished. The result proves the platform can simulate the battle process of air defense missile weapon system, support the simulation work of air defense weapon at different …

Analysis And Optimization Of Combustion Characteristics Of Cement Kiln Cooperatively Disposing Domestic Refuse, Jingbing Wu, Hanqing Tang, Xu Jun

Journal of System Simulation

Abstract: Because the traditional methods can hardly analyze the complex combustion characteristics of cement kiln mixed with domestic refuse, a data mining technology is introduced. A domestic cement plant is selected as the object, and its operating data and relevant parameters are collected. The influence coefficient of each parameter on coal consumption and NO_x emission is analyzed by using Stability Selection algorithm. The mathematical model of coal consumption and NO_x emission is established with Random Forest algorithm, and the key optimization parameters and their optimal values are obtained by K-means clustering algorithm. The result shows that this method …

An Enhanced Multi-Modal Function Optimization Fireworks Algorithm Base On Loser-Out Tournament, Xiaoning Shen, Wang Qian, Huang Yao, You Xuan

Journal of System Simulation

Abstract: An enhanced multi-modal fireworks algorithm based on the loser-out tournament is proposed. A new position-based mapping rule is used to map the explosion sparks beyond the upper boundary of the explosion space to the area near the upper boundary, and to map the one below the lower boundary to the area near the lower boundary. A strategy which adaptively adjusts the number of explosion sparks is introduced to better balance the global and local search abilities of the algorithm. The 28 functions in the CEC2013 standard test function set are selected to the test. Experimental results show that the …

A Xor-Based Visual Cryptography Scheme For (2, N) Access Structure With Ideal Structure Division, Yuqiao Cheng, Zhengxin Fu, Bin Yu

Journal of System Simulation

Abstract: We propose a XOR-based visual cryptography scheme for (2, n) access structures. According to the definition of ideal access structure, the relationship of shares among the minimal qualified subsets is analyzed. And based on it, a division algorithm of access structures is presented with the theory of graph. By this approach, we can obtain the least number of ideal access structures. Additionally the processes of secret sharing and recovering are given. Experimental results show that this scheme can achieve a perfect secret recovery. Compared with existing schemes, the pixel expansion of our paper is the best.

Study On Hardware-In-Loop Simulation Of Space-Feed Low-Frequency Guidance With Turntable External, Linpeng Wang, Chaolei Wang, Yuting Dai

Journal of System Simulation

Abstract: Low-frequency detection, tracking and guidance of stealthy targets need new requirements for hardware-in-loop simulation verification technology. Turntable built-in usually produces electromagnetic interference to seeker. A turntable external method for space- feed low-frequency guidance of hardware in- loop simulation system is proposed. The space-feed low-frequency guidance simulation model is established, and the influence of turntable electromagnetic interference on the seeker is completely eliminated by the turntable external. The simulation environment of non-inertial space motion is constructed to solve the information fusion problem of multiple spaces for hardware-in-loop simulation. The feasibility of the simulation method is verified. The results show that …