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Medicine and Health Sciences Commons

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1998

University of Nebraska - Lincoln

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Articles 1 - 30 of 35

Full-Text Articles in Medicine and Health Sciences

Parent Influences On Adolescent Peer Orientation And Substance Use: The Interface Of Parenting Practices And Values, Karen Bogenschneider, Ming-Yeh Wu, Marcela Raffaelli, Jenner C. Tsay Dec 1998

Parent Influences On Adolescent Peer Orientation And Substance Use: The Interface Of Parenting Practices And Values, Karen Bogenschneider, Ming-Yeh Wu, Marcela Raffaelli, Jenner C. Tsay

Department of Psychology: Faculty Publications

This study examines how experiences in the family domain may magnify or mitigate experiences in the peer domain, and how processes in both milieus may influence adolescent substance use. The data derived from 666 European American mother-adolescent dyads and 510 European American father-adolescent dyads. Consistent with individuation-connectedness theory, mothers’ responsiveness lessened their adolescents’ orientation to peers, which, in turn, reduced adolescent substance use. This process was moderated by maternal values regarding adolescent alcohol use; that is, the relation of maternal responsiveness to adolescent substance use depended on the extent of maternal approval or disapproval of adolescent alcohol use. Among fathers, …


Morphine-Conditioned Changes In Locomotor Activity: Role Of The Conditioned Stimulus, Rick A. Bevins, Michael T. Bardo Dec 1998

Morphine-Conditioned Changes In Locomotor Activity: Role Of The Conditioned Stimulus, Rick A. Bevins, Michael T. Bardo

Department of Psychology: Faculty Publications

When a multisensory environment was reliably paired with morphine (2 mg/kg) in rats, that environment, in a drug-free test, evoked a hyperactive conditioned response (CR). When an olfactory cue (banana odor) was the only stimulus element reliably paired with morphine, it also elicited a hyperactive CR. However, a gustatory cue (saccharin solution) evoked a hypoactive CR. This taste-elicited decrease in activity was dose dependent; morphine at 2 and 4 mg/kg conditioned hypoactivity, whereas a higher dose (8 mg/kg) did not. A robust conditioned saccharin aversion occurred only at the highest dose of morphine, suggesting disassociation between the hypoactive CR and …


Reconsidering The Hiv/Aids Prevention Needs Of Latino Women In The United States, Marcela Raffaelli, Mariana Suarez-Al-Adam Nov 1998

Reconsidering The Hiv/Aids Prevention Needs Of Latino Women In The United States, Marcela Raffaelli, Mariana Suarez-Al-Adam

Department of Psychology: Faculty Publications

The HIV/AIDS epidemic represents an ever-increasing threat to Latino populations in the United States, with women being most affected by this deadly disease. In this chapter, we explore the challenges Latino women face as they attempt to reduce their risk of sexual transmission of HIV, the virus that causes AIDS. Our main interest lies in examining how the economic, cultural, and social realities of women's lives contribute to their risk of HIV infection and constrain their ability to reduce that risk. Because there is neither a cure for AIDS nor a vaccination to block HIV transmission, prevention of infection is …


New Directions In The Application Of Social-Skills Interventions With Adolescents: Introduction To The Special Section, Douglas W. Nangle, David J. Hansen Nov 1998

New Directions In The Application Of Social-Skills Interventions With Adolescents: Introduction To The Special Section, Douglas W. Nangle, David J. Hansen

Department of Psychology: Faculty Publications

The importance of competent social interactions for adolescent adjustment and successful functioning at home, school, work, and social settings has been well documented (cf. Hansen, Giacoletti, & Nangle, 1995; Kelly & Hansen, 1987; Peterson & Hamburg, 1986). Within a developmental context marked by transitions, establishing and maintaining competent social interactions can be particularly challenging for adolescents. Fundamental developmental changes, including the onset of puberty, the emergence of more advanced cognitive and verbal abilities, and the transition into new roles in society, significantly alter social interactions (Bierman & Montminy, 1993; Hansen et al., 1995). These interactions become increasingly complicated and adult-like, …


Adolescent Heterosocial Competence Revisited: Implications Of An Expanded Conceptualization For The Prevention Of High-Risk Sexual Interactions, Douglas W. Nangle, David J. Hansen Nov 1998

Adolescent Heterosocial Competence Revisited: Implications Of An Expanded Conceptualization For The Prevention Of High-Risk Sexual Interactions, Douglas W. Nangle, David J. Hansen

Department of Psychology: Faculty Publications

The current HIV/AIDS epidemic has revitalized interest in adolescent sexual behavior and led to exciting new lines of prevention research. Researchers have concluded that awareness of the risks associated with high-risk sexual behavior alone is not enough to change the behavior of adolescents. Cognitive behavioral skills interventions that directly teach adolescents new skills are now widely recommended as components of prevention efforts. Although social-skills training has often been included as a component of such interventions, we actually know little about how social skills and adolescent sexual behavior are related. This paper provides a conceptual framework based on social-learning theory for …


Enhancing The Effectiveness Of Social Skills Interventions With Adolescents, David J. Hansen, Douglas W. Nangle, Kathryn A. Meyer Nov 1998

Enhancing The Effectiveness Of Social Skills Interventions With Adolescents, David J. Hansen, Douglas W. Nangle, Kathryn A. Meyer

Department of Psychology: Faculty Publications

Competent social interactions are clearly necessary for adjustment and successful functioning in society. The many developmental events and changing social expectations that occur during adolescence can make it particularly challenging for youth to establish and maintain competent social interactions. Research on social skills training with adolescents began in the mid-tolate 1970’s and it has improved much over the years. The research has gradually moved beyond a focus on basic skill assessment and acquisition in clinical settings toward techniques designed to assess and promote generalization and maintenance of an effective interpersonal repertoire in real world settings and situations. This article discusses …


A Protein Encoded By The Latency-Related Gene Of Bovine Herpesvirus 1 Is Expressed In Trigeminal Ganglionic Neurons Of Latently Infected Cattle And Interacts With Cyclin-Dependent Kinase 2 During Productive Infection, Yunquan Jiang, Ashfaque Hossain, Mariah Teresa Winkler, Todd Holt, Alan R. Doster, Clinton J. Jones Oct 1998

A Protein Encoded By The Latency-Related Gene Of Bovine Herpesvirus 1 Is Expressed In Trigeminal Ganglionic Neurons Of Latently Infected Cattle And Interacts With Cyclin-Dependent Kinase 2 During Productive Infection, Yunquan Jiang, Ashfaque Hossain, Mariah Teresa Winkler, Todd Holt, Alan R. Doster, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Despite productive viral gene expression in the peripheral nervous system during acute infection, the bovine herpesvirus 1 (BHV-1) infection cycle is blocked in sensory ganglionic neurons and consequently latency is established. The only abundant viral transcript expressed during latency is the latency-related (LR) RNA. LR gene products inhibit S-phase entry, and binding of the LR protein (LRP) to cyclin A was hypothesized to block cell cycle progression. This study demonstrates LRP is a nuclear protein which is expressed in neurons of latently infected cattle. Affinity chromatography indicated that LRP interacts with cyclin-dependent kinase 2 (cdk2)-cyclin complexes or cdc2-cyclin complexes in …


Pathogenicity Of An Enterotoxigenic Escherichia Coli Hemolysin (Hlya) Mutant In Gnotobiotic Piglets, Rodney A. Moxley, Emil M. Berberov, David H. Francis, Jun Xing, Mahtab Moayeri, Rodney A. Welsch, Diane R. Baker, Raul G. Barletta Oct 1998

Pathogenicity Of An Enterotoxigenic Escherichia Coli Hemolysin (Hlya) Mutant In Gnotobiotic Piglets, Rodney A. Moxley, Emil M. Berberov, David H. Francis, Jun Xing, Mahtab Moayeri, Rodney A. Welsch, Diane R. Baker, Raul G. Barletta

School of Veterinary and Biomedical Sciences: Faculty Publications

Pigs infected with hemolytic F4+ strains of enterotoxigenic Escherichia coli often develop septicemia secondary to intestinal infection. We tested the hypothesis that inactivation of hemolysin would reduce the ability of F4+ enterotoxigenic E. coli to cause septicemia in swine following oral inoculation. Inactivation of the hemolysin structural gene (hlyA) did not decrease the incidence of septicemia in the gnotobiotic piglet model.


Alternative Splicing Of The Latency-Related Transcript Of Bovine Herpesvirus 1 Yields Rnas Containing Unique Open Reading Frames, Laxminarayana R. Devireddy, Clinton J. Jones Sep 1998

Alternative Splicing Of The Latency-Related Transcript Of Bovine Herpesvirus 1 Yields Rnas Containing Unique Open Reading Frames, Laxminarayana R. Devireddy, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

The latency-related transcript (LRT) of bovine herpesvirus 1 (BHV-1) is the only abundant viral RNA detected during latency. A previous study (A. Hossain, L. M. Schang, and C. Jones, J. Virol. 69:5345–5352, 1995) concluded that splicing of polyadenylated [poly(A) +] and splicing of nonpolyadenylated [poly(A) -] LRT are different. In this study, splice junction sites of LRT were identified. In trigeminal ganglia of acutely infected calves (1, 7, or 15 days postinfection [p.i.]) or in latently infected calves (60 days p.i.), alternative splicing of poly(A) + LRT occurred. Productive viral gene expression in trigeminal ganglia is readily detected …


Prediction Of Health Patterns From General Appraisal, Attributions, Coping, And Trait Anxiety, Scott Hemenover, Richard A. Dienstbier Sep 1998

Prediction Of Health Patterns From General Appraisal, Attributions, Coping, And Trait Anxiety, Scott Hemenover, Richard A. Dienstbier

Department of Psychology: Faculty Publications

We examined the relationships among general appraisal style, attributional style, trait anxiety, coping styles, and health status (i.e., depression, hostility, and flu-like symptoms) in a study for which we also examined the validity of a trait measure of general appraisal. Participants completed personality measures at the beginning of an academic semester, and health assessments at regular intervals throughout the semester. Consistent with our predictions, after removing the influence of neuroticism and attributional style, general appraisal style led to more negative, and less positive affect 2 weeks later, and to more stressful and threatening appraisals of a life event occurring 3 …


Methodological Considerations In Pretrial Publicity Research: Is The Medium The Message?, Jeffrey R. Wilson, Brian H. Bornstein Aug 1998

Methodological Considerations In Pretrial Publicity Research: Is The Medium The Message?, Jeffrey R. Wilson, Brian H. Bornstein

Department of Psychology: Faculty Publications

Two methodological issues within the pretrial publicity (PTP) literature were examined in the present experiment: the effect of emotional versus factual PTP and the effect of presenting PTP through different media. Emotional and factual PTP were constructed that differed in level of emotionality, but produced the same degree of bias. The PTP was presented in either a videotaped or written format. Although there was a significantly biasing effect of PTP overall compared to a control condition, no significant difference was found either between factual and emotional PTP or between video and written PTP.


Attention Effects On Distortion Product Otoacoustic Emissions With Contralateral Speech Stimuli, Genaya Kae Timpe Aug 1998

Attention Effects On Distortion Product Otoacoustic Emissions With Contralateral Speech Stimuli, Genaya Kae Timpe

College of Education and Human Sciences: Dissertations, Theses, and Student Research

The purpose of the present study was to investigate the effect of attending to a speech stimulus on the amplitude of the distortion product otoacoustic emission (DPOAE). The distortion product otoacoustic emission is a measurement of the activity of the inner ear, specifically the outer hair cells in the ear. The activity of the outer hair cells depends upon the auditory nervous system; when it is stimulated, the outer hair cell activity is modified. Normal outer hair cells will create a large DPOAE amplitude. When a stimulus is presented to the opposite ear, the auditory nervous system acts upon the …


Effects Of Weapons On Guilt Judgments And Sentencing Recommendations For Criminals, Richard A. Dienstbier, Scott C. Roesch, Ayumi Mizumoto, S. H. Hemenover, Roger C. Lott, Gustavo Carlo Jun 1998

Effects Of Weapons On Guilt Judgments And Sentencing Recommendations For Criminals, Richard A. Dienstbier, Scott C. Roesch, Ayumi Mizumoto, S. H. Hemenover, Roger C. Lott, Gustavo Carlo

Department of Psychology: Faculty Publications

In Study 1,we explored whether guns presented for target shooting would lead subjects to assign longer prison sentences for crimes unrelated to the guns. Weapon-condition subjects recommended longer sentences than did control subjects, who had experienced equally energizing sports activities. In Study 2, subjects acting as jurors watched a police officer’s videotaped deposition about a burglary arrest. Through the deposition, subjects in all conditions received identical information about the gun. However, some subjects heard the description of the gun taken from the burglar; some heard the description and saw the gun when it was placed on the evidence table near …


Parent-Teen Communication About Sexual Topics, Marcela Raffaelli, Karen Bogenschneider, Mary Fran Flood May 1998

Parent-Teen Communication About Sexual Topics, Marcela Raffaelli, Karen Bogenschneider, Mary Fran Flood

Department of Psychology: Faculty Publications

Parent-teen communication about sexual topics was examined in 666 mother-teen and 510 father-teen pairs. Parents and their 8th- through 12th-grade children completed parallel surveys that assessed demographic, relationship, and attitudinal variables hypothesized to be linked to sexual communication. Logistic regression analyses were used to determine which variables were linked to teens’ reports of “one good talk” about each of three sexual topics (whether teen sex is okay, the dangers of AIDS and other sexually transmitted diseases, and birth control) in the past year. Aside from gender of parents and teens, demographic variables were largely nonsignificant in the final models. Instead, …


“Other Teens Drink, But Not My Kid”: Does Parental Awareness Of Adolescent Alcohol Use Protect Adolescents From Risky Consequences?, Karen Bogenschneider, Ming-Yeh Wu, Marcela Raffaelli, Jenner C. Tsay May 1998

“Other Teens Drink, But Not My Kid”: Does Parental Awareness Of Adolescent Alcohol Use Protect Adolescents From Risky Consequences?, Karen Bogenschneider, Ming-Yeh Wu, Marcela Raffaelli, Jenner C. Tsay

Department of Psychology: Faculty Publications

This study included 199 White mother-adolescent dyads and 144 White father-adolescent dyads. All adolescents reported regular alcohol use, yet less than one third of parents were aware of their adolescents’ drinking. Parental awareness of adolescent alcohol use served to protect adolescents by moderating the relation of parents’ responsiveness to episodes of drinking and driving. Aware parents were more likely than unaware parents to believe their adolescents’ close friends drank alcohol. Aware mothers worried more about their adolescents’ risk behaviors and discussed them more frequently with their adolescents. Aware fathers held values less disapproving of adolescent alcohol use and were less …


From Compassion To Compensation: The Effect Of Injury Severity On Mock Jurors’ Liability Judgments, Brian H. Bornstein Mar 1998

From Compassion To Compensation: The Effect Of Injury Severity On Mock Jurors’ Liability Judgments, Brian H. Bornstein

Department of Psychology: Faculty Publications

Two studies were performed to ascertain the effect of injury severity on participants’ judgments in a simulated jury task. Participants read a summary of a personal-injury case in which the severity of the plaintiff’s injury was varied: they were asked to judge the defendant’s liability, award compensation, and rate their feelings toward the litigants. In Study 1, more severely hurt plaintiffs were more likely to obtain a favorable verdict, even though evidence of liability was held constant. Greater severity influenced liability judgments only insofar as it elicited positive feelings toward the plaintiff or negative feelings toward the defendant. In Study …


Predictors Of Children’S Risk Appraisals, David Dilillo, Richard Potts, Susan Himes Mar 1998

Predictors Of Children’S Risk Appraisals, David Dilillo, Richard Potts, Susan Himes

Department of Psychology: Faculty Publications

This study explored variables associated with cognitive appraisals of physical risk in a sample of 62 elementary school children. Participants were presented with drawings of persons in three categories of risky situations typical of children, typical of adults, and typical of television plots. They were asked to judge the potential for physical injury in each. Results indicated that children tended to appraise risks in child, adult, and TV-plot risk situations differently, and that each type of situation was predicted by different variables. For the child situations, greater amounts of direct experience with the risk situation itself was found to be …


Differentiating Withdrawal Patterns Between Smokers And Smokeless Tobacco Users, Dennis E. Mcchargue, Frank L. Collins Jr. Mar 1998

Differentiating Withdrawal Patterns Between Smokers And Smokeless Tobacco Users, Dennis E. Mcchargue, Frank L. Collins Jr.

Department of Psychology: Faculty Publications

The present study was designed to document smokeless tobacco withdrawal patterns and to examine differential withdrawal responses between smokers and smokeless users. Participants (N = 19) were studied under deprivation and nondeprivation conditions, 1 condition per week. The Withdrawal Symptoms Checklist was administered to assess cognitive and affective changes. Both smokers and smokeless users experienced substantially more withdrawal at 48-hr deprivation compared to the 48-hr nondeprivation condition. Participants in both groups endorsed decreasingly fewer withdrawal symptoms from 0 hr to 48 hr on nondeprivation days. This downward trend suggests a need for stabilizing withdrawal responses before deprivation.


The Role Of Ease Of Retrieval And Attribution In Memory Judgments: Judging Your Memory As Worse Despite Recalling More Events, Piotr Winkielman, Norbert Schwarz, Robert Belli Mar 1998

The Role Of Ease Of Retrieval And Attribution In Memory Judgments: Judging Your Memory As Worse Despite Recalling More Events, Piotr Winkielman, Norbert Schwarz, Robert Belli

Department of Psychology: Faculty Publications

Abstract—Participants who had to recall 12 childhood events (a difficult task) were more likely to infer that they could not remember large parts of their childhood than participants who had to recall 4 events (an easy task), although the former recalled three times as many events. This pattern of results suggests that memory judgments are based on the experienced ease or difficulty of recall. Accordingly, the negative impact of recalling 12 events was attenuated when participants were led to attribute the experienced difficulty to the task rather than to the poor quality of their memory. The findings emphasize the role …


Repeated Testing In Eyewitness Memory: A Means To Improve Recall Of A Negative Emotional Event, Brian H. Bornstein, Lesley M. Liebel, Nikki C. Scarberry Feb 1998

Repeated Testing In Eyewitness Memory: A Means To Improve Recall Of A Negative Emotional Event, Brian H. Bornstein, Lesley M. Liebel, Nikki C. Scarberry

Department of Psychology: Faculty Publications

Participants viewed either a violent, arousing film or a non-violent, control version of the same film. After viewing the film, they made three successive attempts to recall details of the event. Participants who were exposed to the negative emotional event were better than control participants at recalling details of the event itself, but they were worse at recalling details that preceded or followed the violence. Both groups of participants recalled significantly more information over successive recall attempts, suggesting that memory impairment due to arousal can be alleviated by repeated testing. Repeated testing was also associated with a small but reliable …


The Greatest Memory Teacher Ever: Review Of Memory’S Ghost: The Nature Of Memory And The Strange Tale Of Mr. M., By Philip J. Hilts, Brian H. Bornstein Feb 1998

The Greatest Memory Teacher Ever: Review Of Memory’S Ghost: The Nature Of Memory And The Strange Tale Of Mr. M., By Philip J. Hilts, Brian H. Bornstein

Department of Psychology: Faculty Publications

Although psychologists and neurologists have been familiar with the case of H.M. for years, this small volume makes his story—and what it can teach us about the functioning of memory—accessible to a much wider audience. Hilts has done a good job of piecing together H.M.’s early life, in the absence of any living relatives and all but a few written records. He recreates the life of a very normal youth in the 1930s and 1940s; normal, that is, until H.M.’s first epileptic seizure. In 1954, after several other treatments for the epilepsy had failed, H.M. (at age 27) had a …


The Saccharomyces Cerevisiae Tsc10/Ybr265w Gene Encoding 3-Ketosphinganine Reductase Is Identified In A Screen For Temperature-Sensitive Suppressors Of The Ca2+-Sensitive Csg2Δ Mutant, Troy Beeler, Dagmar Bacikova, Ken Gable, Lisa Hopkins, Courtney Johnson, Harry Slife, Teresa Dunn Jan 1998

The Saccharomyces Cerevisiae Tsc10/Ybr265w Gene Encoding 3-Ketosphinganine Reductase Is Identified In A Screen For Temperature-Sensitive Suppressors Of The Ca2+-Sensitive Csg2Δ Mutant, Troy Beeler, Dagmar Bacikova, Ken Gable, Lisa Hopkins, Courtney Johnson, Harry Slife, Teresa Dunn

Uniformed Services University of the Health Sciences

Saccharomyces cerevisiae csg2Δ mutants accumulate the sphingolipid inositolphosphorylceramide, which renders the cells Ca2+-sensitive. Temperature-sensitive mutations that suppress the Ca2+ sensitivity of csg2Δ mutants were isolated and characterized to identify genes that encode sphingolipid synthesis enzymes. These temperature-sensitive csg2Δ suppressors (tsc) fall into 15 complementation groups. The TSC10/YBR265w gene was found to encode 3-ketosphinganine reductase, the enzyme that catalyzes the second step in the synthesis of phytosphingosine, the long chain base found in yeast sphingolipids. 3-Ketosphinganine reductase (Tsc10p) is essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine. Tsc10p is a member of the …


Polyadenylation Of Vesicular Stomatitis Virus Mrna Dictates Efficient Transcription Termination At The Intercistronic Gene Junctions, Leroy N. Hwang, Nathan Englund, Asit K. Pattnaik Jan 1998

Polyadenylation Of Vesicular Stomatitis Virus Mrna Dictates Efficient Transcription Termination At The Intercistronic Gene Junctions, Leroy N. Hwang, Nathan Englund, Asit K. Pattnaik

School of Veterinary and Biomedical Sciences: Faculty Publications

The intercistronic gene junctions of vesicular stomatitis virus (VSV) contain conserved sequence elements that are important for polyadenylation and transcription termination of upstream transcript as well as reinitiation of transcription of downstream transcript. To examine the role of the putative polyadenylation signal 3' AUACU75' at the gene junctions in polyadenylation and transcription termination, we constructed plasmids encoding antigenomic minireplicons containing one or two transcription units. In plasmid-transfected cells, analyses of the bicistronic minireplicon containing the wild-type or mutant intercistronic gene junctions for the ability to direct synthesis of polyadenylated upstream, downstream, and readthrough mRNAs showed that the AUACU …


What Is Learned About Nontarget Items In Simple Visual Search?, John H. Flowers, Karen L. Smith Jan 1998

What Is Learned About Nontarget Items In Simple Visual Search?, John H. Flowers, Karen L. Smith

Department of Psychology: Faculty Publications

Human sensitivity to correlational structure between nontargets and likelihood of target presence in a visual letter-search task were studied in two experiments. In each of these experiments, the performance of subjects for whom the nontarget information was altered in the final trial block was compared with the performance of subjects for whom the nontarget information did not change. When stimulus strings were presented individually on a computer screen and subjects were required to make a yes–no decision about target presence (Experiment 1), the change in nontarget structure resulted in increased reaction times for target-absent trials. When subjects searched simultaneously for …


Partner, Teacher, And Guide: Examples Of Teacher Behavior In Reggio Emilia, Carolyn P. Edwards Jan 1998

Partner, Teacher, And Guide: Examples Of Teacher Behavior In Reggio Emilia, Carolyn P. Edwards

Department of Psychology: Faculty Publications

To give a fuller picture and provide concrete examples of the abstract principles presented above, we offer four short observation records drawn from videotapes taken at the Diana School in 1988 and 1990. They illustrate different kinds of teacher behavior commonly seen in the Reggio Emilia preprimary schools.

The Teacher Gets Children Started
The Teacher Provides Instruction in Tool-Use and Technique
The Teacher Turns a Dispute into a Hypothesis to Test
The Teacher Encourages Children to Solve Their Own Disputes


A Prolonged Outbreak Of Shigella Sonnei Infections In Traditionally Observant Jewish Communities In North America Caused By A Molecularly Distinct Bacterial Subtype, Jeremy Sobel, Daniel N. Cameron, Johanne Ismail, Nancy Strockbine, Michael Williams, Pamela S. Diaz, Barbara Westley, Marilyn Rittmann, Joseph Dicristina, Halina Ragazzoni, Robert V. Tauxe, Eric D. Mintz Jan 1998

A Prolonged Outbreak Of Shigella Sonnei Infections In Traditionally Observant Jewish Communities In North America Caused By A Molecularly Distinct Bacterial Subtype, Jeremy Sobel, Daniel N. Cameron, Johanne Ismail, Nancy Strockbine, Michael Williams, Pamela S. Diaz, Barbara Westley, Marilyn Rittmann, Joseph Dicristina, Halina Ragazzoni, Robert V. Tauxe, Eric D. Mintz

Public Health Resources

During 1994–1996, Shigella sonnei outbreaks occurred in 8 North American traditionally observant Jewish communities. These communities remain relatively separate from neighboring populations while maintaining close contact by travel with coreligionists in other cities. Epidemiologic investigations suggested community-to-community transmission via travel. Outbreak-related and control isolates of S. sonnei from each city were subtyped by pulsed-field gel electrophoresis (PFGE) to confirm an epidemiologic linkage between outbreaks. Forty-three (94%) of 46 outbreak-related isolates had closely related PFGE patterns, constituting a single subtype; 33 (94%) of 35 control isolates demonstrated unrelated PFGE patterns. Several patterns differing by 3 bands were identified within the …


Human Granulocytic Ehrlichiosis In Europe: Clinical And Laboratory Findings For Four Patients From Slovenia, Stanka Lotric-Furlan, Miroslav Petrovec, Tatjana Avsic Zupanc, William L. Nicholson, John W. Sumner, James E. Childs, Franc Strle Jan 1998

Human Granulocytic Ehrlichiosis In Europe: Clinical And Laboratory Findings For Four Patients From Slovenia, Stanka Lotric-Furlan, Miroslav Petrovec, Tatjana Avsic Zupanc, William L. Nicholson, John W. Sumner, James E. Childs, Franc Strle

Other Publications in Zoonotics and Wildlife Disease

Febrile illnesses following a tick bite in patients from Slovenia were evaluated for an ehrlichial etiology. A case of acute human granulocytic ehrlichiosis (HGE) was confirmed by seroconversion to the HGE agent or molecular identification of ehrlichial organisms. Acute infection with the HGE agent was confirmed in four patients. None of the patients had detectable antibodies to the HGE agent at their first visit, but polymerase chain reaction analysis was positive for three patients. All four patients subsequently seroconverted to the HGE agent as shown by high titers of antibody. Clinical features and laboratory findings were similar to those in …


Ecologic Studies Of Rodent Reservoirs: Their Relevance For Human Health, James N. Mills, James E. Childs Jan 1998

Ecologic Studies Of Rodent Reservoirs: Their Relevance For Human Health, James N. Mills, James E. Childs

Other Publications in Zoonotics and Wildlife Disease

Within the past few years, the number of “new” human diseases associated with small-mammal reservoirs has increased dramatically, stimulating renewed interest in reservoir ecology research. A consistent, integrative approach to such research allows direct comparisons between studies, contributes to the efficient use of resources and data, and increases investigator safety. We outline steps directed toward understanding vertebrate host ecology as it relates to human disease and illustrate the relevance of each step by using examples from studies of hosts associated with rodent-borne hemorrhagic fever viruses.


Serologic Evidence Of Infection With Ehrlichia Spp. In Wild Rodents (Muridae: Sigmodontinae) In The United States, William L. Nicholson, Susie Muir, John W. Sumner, James E. Childs Jan 1998

Serologic Evidence Of Infection With Ehrlichia Spp. In Wild Rodents (Muridae: Sigmodontinae) In The United States, William L. Nicholson, Susie Muir, John W. Sumner, James E. Childs

Other Publications in Zoonotics and Wildlife Disease

Rodent (Muridae: Sigmodontinae) blood and sera collected from 14 states were tested for seroreactivity to a cultured isolate of the human granulocytic ehrlichiosis (HGE) agent by using an indirect immunofluorescence assay. Of the 1,240 samples tested, 136 (11%) were found to be reactive at titers of ≥32. Rodents with HGE agent-specific antibodies were found in New York (23% of 491 samples; geometric mean endpoint titer GMT = 441), Connecticut (11% of 100 samples; GMT = 481), California (9% of 32 samples; GMT = 323), Colorado (2% of 212 samples; GMT = 256), Florida (7% of 27 samples; GMT = 362), …


Dietary Habits Of The Common Rodents In An Agrecosystem In Argentina, Barbara A. Ellis, James N. Mills, Gregory E. Glass, Kelly T. Mckee Jr, Delia A. Enria, James E. Childs Jan 1998

Dietary Habits Of The Common Rodents In An Agrecosystem In Argentina, Barbara A. Ellis, James N. Mills, Gregory E. Glass, Kelly T. Mckee Jr, Delia A. Enria, James E. Childs

Other Publications in Zoonotics and Wildlife Disease

Dietary habits of five common rodents in agroecosystems on the central Argentine Pampa were studied for 15 months using microhistological analysis of stomach contents. All five rodent species were omnivorous, but proportions of major dietary items (arthropods, dicot leaves and seeds, monocot leaves and seeds) varied among species and seasons. Akodon azarae largely was entomophagous; arthropods formed 41-62% of the diet in all seasons. The other four species (Calomys musculinus, Calomys laucha, Bolomys obscurus, and Oligoryzomys flavescens) consumed most diet items throughout the year, but relative proportions varied among seasons. Leaves formed a relatively minor proportion of the …