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Design Of A Collimated Line Source For Transmission Ct Imaging Of The Head With A Spect System, Brad James Kemp Jan 1995

Design Of A Collimated Line Source For Transmission Ct Imaging Of The Head With A Spect System, Brad James Kemp

Digitized Theses

Single photon emission computed tomography (SPECT) has the potential to provide absolute quantitative information about the function of an organ. However, two factors which limit accurate quantification are the attenuation of the gamma rays emitted from the radiopharmaceutical concentration and the inability to define the anatomic region being quantified. Presented in this thesis is an attenuation correction that compensates SPECT brain images for attenuation and a transmission imaging system that (a) provides the distribution of attenuation coefficients required for the attenuation compensation and (b) simplifies regional identification by registering the functional SPECT images onto the anatomic transmission images. The attenuation …


Intermolecular Forces And Statistical Mechanics Of Liquids, Maria Koulis Jan 1995

Intermolecular Forces And Statistical Mechanics Of Liquids, Maria Koulis

Digitized Theses

This research is involved with the construction of potential energy models for the interaction of closed shell atoms and/or molecules and with the study of the thermodynamic properties of pure liquids and liquid mixtures, through the use of statistical mechanical perturbation theory.;The previously developed Exchange-Coulomb potential energy model for the interaction of closed shell atoms is modified to correct its unphysical behaviour for small interspecies distances and so that it is applicable for interactions involving molecules. The new potential energy model is based on using the Heitler-London energy to represent the repulsive part, and a damped and overall corrected dispersion …


An Examination Of Whether Irony And Sarcasm Are Different Terms For The Same Psychological Construct, Christopher James Lee Jan 1995

An Examination Of Whether Irony And Sarcasm Are Different Terms For The Same Psychological Construct, Christopher James Lee

Digitized Theses

Researchers have studied counterfactual statements, such as "There's not a cloud in the sky!" uttered during a violent thunderstorm, both as instances of irony (Jorgensen, Miller & Sperber, 1984; Kreuz & Glucksberg, 1989; Katz & Lee, 1993) and as instances of sarcasm (Gibbs, 1986; Kreuz & Glucksberg, 1989). It is not surprising that some terms are used inconsistently in a young field of investigation such as the psycholinguistics of irony and sarcasm. However. the inconsistent use of the terms irony and sarcasm across different empirical studies is problematic when research participants are asked to judge whether or not counterfactual statements …


Commercial Integrity, Roles And Object-Orientation, Matunda Nyanchama Jan 1995

Commercial Integrity, Roles And Object-Orientation, Matunda Nyanchama

Digitized Theses

This thesis presents a study of realizing commercial security, as defined in the Clark and Wilson Model (CW87), using Object-Oriented (O-O) concepts.;Role-based security is implied in the Clark and Wilson model in which specified operations are grouped to compose roles. This approach to protection is suitable for applications involving large numbers of users with overlapping user requirements and/or where there is a large number of objects. It presents a flexible (hence adaptive) means for enforcing differing ranges of security policies. It enforces the principle of least privilege, hence minimizing the risk of Trojan horse attacks.;Consequently, in part, this work focuses …


High Temperature X-Ray Diffraction Investigation Of The Beta-(Bismuth(2) Oxygen(3))(1-X)(Strontium Oxide)(X) Solid Solution, Edward Andrew Payzant Jan 1995

High Temperature X-Ray Diffraction Investigation Of The Beta-(Bismuth(2) Oxygen(3))(1-X)(Strontium Oxide)(X) Solid Solution, Edward Andrew Payzant

Digitized Theses

To investigate the controversial {dollar}\beta\sb1\leftrightarrow\beta\sb2{dollar} phase transformation in the {dollar}\beta{dollar}-{dollar}\rm (Bi\sb2O\sb3)\sb{lcub}1-x{rcub}(SrO)\sb{lcub}x{rcub}{dollar} phase, a series of compositions across the phase were prepared by conventional grinding, pressing and firing ceramic techniques. Electrical conductivity measurements demonstrated that the samples were comparable to those used in other laboratories. X-ray diffraction analysis confirmed that the cations are located on a hexagonal sublattice, but details of the anion sublattice could not be resolved, because of the low X-ray scattering factor of {dollar}\rm O\sp{lcub}2-{rcub}.{dollar};The compositional dependence of the lattice parameters of the hexagonal crystal structure of the {dollar}\beta{dollar}-{dollar}\rm (Bi\sb2O\sb3)\sb{lcub}1-x{rcub}(SrO)\sb{lcub}x{rcub}{dollar} phase, which was determined at {dollar}27\sp\circ\rm C{dollar} using …


Social Rank And Foraging Behavior In Rats: Effects Of Food Size, Density And Distribution, Maria Phelps Jan 1995

Social Rank And Foraging Behavior In Rats: Effects Of Food Size, Density And Distribution, Maria Phelps

Digitized Theses

A number of field studies, conducted with birds, have found that dominant birds aggress against subordinate birds to attain priority of access to food. However, the level of aggression exhibited by dominant birds varied in accord with a cost-benefit analysis of the physical properties and spatial organization of the resource base. When the costs of aggression exceeded the benefits gained from resource defense, dominant birds decreased the level of aggression. Because rats also forage in groups and form functional social hierarchies, it was predicted that dominant rats, like dominant birds, would decrease aggression as a function of three resource attributes. …


On The Palmitoylation Of Surfactant-Associated Protein C, Riad Qanbar Jan 1995

On The Palmitoylation Of Surfactant-Associated Protein C, Riad Qanbar

Digitized Theses

Surfactant-associated protein C (SP-C) contributes to the surface active properties of pulmonary surfactant. Processed from a 21 kDa precursor, the mature form of SP-C is 34-35 amino acids in length. Both the precursor and the mature protein are modified by palmitoylation. Due to its small size and extreme hydrophobicity, SP-C has been difficult to isolate, detect and study. Using molecular exclusion chromatography, SP-C was isolated from calf lung surfactant extract, characterized by partial sequencing, amino acid analysis, tricine polyacrylamide gel electrophoresis, and absence of immune-reactivity with antibodies raised against surfactant-associated protein B (SP-B). A method was developed to label, detect …


Circular Dichroism And Luminescence Studies Of Copper Binding To Metallothionein, Paul Anthony Presta Jan 1995

Circular Dichroism And Luminescence Studies Of Copper Binding To Metallothionein, Paul Anthony Presta

Digitized Theses

The metallothioneins (MT) are a class of low molecular weight, cysteine rich proteins found in almost all living things. The high sulfhydryl content imparts to these proteins the unique ability to bind a wide range of metals. The metallothioneins have been implicated in the storage and transport of essential metals, such as zinc and copper, and in the detoxification of toxic metals, such as cadmium. However, the exact physiological functions of these proteins remain a matter of speculation. In particular, little is known about the interactions of copper with MT. In this thesis, the structural and mechanistic properties of copper …


Neurotransmission Of Visceral Information In The Parabrachial Nucleus Of The Rat, Tarek Saleh Jan 1995

Neurotransmission Of Visceral Information In The Parabrachial Nucleus Of The Rat, Tarek Saleh

Digitized Theses

The parabrachial nucleus (PB) has been shown to be a major relay site for visceral afferents ascending through the ventrobasal thalamus and terminating in the insular cortex. The purpose of these investigations was to determine the neurotransmitter mechanisms in the PB involved in relaying visceral sensory information to the thalamus in the rat. Using electrophysiological techniques in the cloral hydrate anesthetised male Wistar rat, our results show that the visceral pathway from the PB to the thalamus appears to use two neuronal systems, one mediating the relay of specific visceral information via glutamatergic N-methyl D-aspartate (NMDA) receptors in the PB, …


Postsynaptic Cholinergic Control Of Cardiac Function In Aging, Na Su Jan 1995

Postsynaptic Cholinergic Control Of Cardiac Function In Aging, Na Su

Digitized Theses

The present study using isolated constant flow-perfused heart from adult (8 month-old) and aged (26 month-old) Fischer 344 rats for the first time demonstrated a striking enhancement of the negative chronotropic, inotropic and coronary vasoconstriction responses of the aging heart to postsynaptic cholinergic stimulation.;The approaches used and the results demonstrated were the following. (i) Acetylcholinesterase activity measured by the method of Ellman et al (1961) declined significantly in the atria and ventricles of the aged compared to adult rats. (ii) No age-related difference was seen in muscarinic receptor number in the atria and ventricles as assessed by {dollar}\lbrack\sp3\rm H\rbrack QNB{dollar} …


The Role Of Literal Meaning In Proverb Comprehension, Nigel E. Turner Jan 1995

The Role Of Literal Meaning In Proverb Comprehension, Nigel E. Turner

Digitized Theses

According to the 'Standard Pragmatic Model of Language', a person initially attempts to understand figurative sentences such as metaphors and proverbs in terms of their literal meaning and only processes the figurative meaning when the literal meaning is found inadequate. Experimental studies have failed to support this model; however, many of these studies confounded literalness with conventionality. Furthermore, the role of literal meaning during figurative language comprehension remains unresolved. The purpose of this thesis is to conduct a more valid test of the Standard Pragmatic Model, and to determine the role of literal meaning during proverb comprehension. In the first …


A New Photocatalytic Reactor For The Photodegradation Of Organic Contaminants In Water, Julio E. Valladares Jan 1995

A New Photocatalytic Reactor For The Photodegradation Of Organic Contaminants In Water, Julio E. Valladares

Digitized Theses

The {dollar}\rm TiO\sb2{dollar} photocatalytic degradation and mineralization of organic pollutants in water has been broadly demonstrated at the laboratory level for a wide number of organic pollutants. However, there are still some problems that need to be addressed in order to make this technology more practical. The design of heterogeneous photocatalytic reactor systems, still in the infancy of their development, is facing different problems such as light scattering, oxygen starving, particle separation and mass transfer. Additionally, there have also been a lack of a general method to evaluate the performance of the different reactor systems.;The present work addresses these problems …


Role Of Protein Kinase C In Mediating The Effects Of Physiological And Pathophysiological Interventions In The Heart, Christopher Andrew Ward Jan 1995

Role Of Protein Kinase C In Mediating The Effects Of Physiological And Pathophysiological Interventions In The Heart, Christopher Andrew Ward

Digitized Theses

Protein kinase C has been implicated as a mediator of myocardial function following both physiological and pathophysiological stimuli. The purpose of the present study was to examine the functional effects of PKC in mediating phorbol esters as well as receptor-induced effects in myocardial tissues. Additionally, the possible role of PKC in mediating cardiac pathophysiology was assessed under conditions which mimicked aspects of myocardial ischemia/reperfusion. The effects of phorbol esters on cardiac function were assessed in isolated perfused guinea pig hearts. The effects of phorbol esters, acidosis/realkalinization and hydrogen peroxide were assessed in isolated guinea pig ventricular myocytes to determine PKC-dependent …


Maternal Depression, Perceptions, Contextual Stress, And Parenting, Christine Marie-Antoinette Wekerle Jan 1995

Maternal Depression, Perceptions, Contextual Stress, And Parenting, Christine Marie-Antoinette Wekerle

Digitized Theses

The relationship between maternal depression and parenting was explored in three distinct ways: (1) the direct effect of maternal depression, as it is measured proximally and distally to parenting, (2) the moderation of proximal and distal maternal depression by contextual stress, and (3) the mediation of proximal and distal maternal depression by maternal perceptions of child problem behaviour. Two aspects of maternal behaviour were examined: aversive parenting (negative control strategies, negative affect, lack of positive control strategies) and positive affect (positive affect and affection).;A community sample of 95 mother-child dyads participated in 12, 1-hr in-home behavioural observations. Also, mothers completed …


Self-Concept Dimensions Associated With Eating Disturbance, Sandra Ann Yuen Jan 1995

Self-Concept Dimensions Associated With Eating Disturbance, Sandra Ann Yuen

Digitized Theses

The present thesis provided a detailed examination of the self-concept variables associated with eating disturbance. Two distinct self-concept variables, namely, the content and evaluative dimensions of self, were evaluated in relation to global measures of bulimia nervosa. These self-concept dimensions were further examined in relation to the eating pathology and general maladjustment features of bulimia, including the behavioural, motivational, and cognitive-affective components of eating disturbance.;Study 1 examined the actual and ideal self-concept content dimensions and the self-certainty and attribute importance evaluative self-dimensions, across the domains of body image, depressive personality, sociability, and social roles. Individuals reporting higher levels of bulimia …


The Interaction Of Thyroid Stimulating Hormone (Tsh), Insulin-Like Growth Factors (Igfs), And Insulin-Like Growth Factor Binding Proteins (Igfpbs) In The Regulation Of The Synthesis And Secretion Of Thyroid Hormones By Cultured Sheep Thyroid Cells, Jia Fang Wang Jan 1995

The Interaction Of Thyroid Stimulating Hormone (Tsh), Insulin-Like Growth Factors (Igfs), And Insulin-Like Growth Factor Binding Proteins (Igfpbs) In The Regulation Of The Synthesis And Secretion Of Thyroid Hormones By Cultured Sheep Thyroid Cells, Jia Fang Wang

Digitized Theses

Thyroid growth and function are regulated by TSH in synergy with other hormones, growth factors, and neurotransmitters. Insulin-like growth factors (IGFs), which have insulin-like effects on metabolism and regulate cell growth and function, are synthesized and secreted by thyroid cells. IGFs are associated with their specific binding proteins (IGFBPs), which not only carry and store IGFs in body fluids but also modulate the biological function of IGFs. Previous studies found that both IGFs and IGFBPs participated in the regulation of the growth of thyroid cells.;This study has further examined the biological function of IGFs and IGFBPs in the regulation of …


Automated Analysis Of Nuclear Medicine Images: Towards Artificial Intelligence Systems, Piotr Jan Slomka Jan 1995

Automated Analysis Of Nuclear Medicine Images: Towards Artificial Intelligence Systems, Piotr Jan Slomka

Digitized Theses

Automated methods for the analysis of nuclear medicine images could provide an objective diagnosis, and means to transfer sophisticated expertise to less experienced centres. The goal of this study was to develop software methods for the automated analysis of (a) Quality Control (QC) images, and (b) myocardial perfusion tomography images.;The system for the automated analysis of QC images was based on feature extraction algorithms, which provided input to a higher level diagnostic expert system. Several features characterizing QC images were defined. Rule-based and object-oriented expert systems were created to guide personnel in QC procedures, detect gamma camera faults, and suggest …


Entrepreneurship In Multinational Corporations: The Initiative Process In Foreign Subsidiaries, Julian Mark Birkinshaw Jan 1995

Entrepreneurship In Multinational Corporations: The Initiative Process In Foreign Subsidiaries, Julian Mark Birkinshaw

Digitized Theses

This is an empirical study of initiatives in the subsidiaries of multinational corporations. An initiative is the subsidiary-driven creation of a value-adding activity. While previous research has focused on the "world product mandates" earned as a result of initiatives, or the corporate systems that facilitate subsidiary initiatives, this study is concerned with the internal processes that actively drive subsidiary initiatives. This issue is of vital importance to subsidiary managers who are looking for ways to enhance their value-added role in the corporation: it also has substantial implications for corporate strategy and for theoretical models of multinational management and entrepreneurship.;Two research …


Legal Fictions, Ian Randall Kerr Jan 1995

Legal Fictions, Ian Randall Kerr

Digitized Theses

Many judges faced with the task of rendering difficult decisions have a habit of pretending things that they know to be false. In so doing they employ legal fiction. Generally, a legal fiction is a false assumption of fact made by a court as the basis for resolving a legal issue. One of its purposes is to reconcile a specific legal result with an established legal rule. Legal fictions are thought to provide a mechanism for preserving the rule while ensuring a just outcome. By feigning the facts, the rule is said to remain intact. Historically, the fiction has achieved …


Evolutionary Models Of Market Behavior, Guo Ying Luo Jan 1995

Evolutionary Models Of Market Behavior, Guo Ying Luo

Digitized Theses

This thesis consists of three evolutionary models examining market behavior.;Profit maximization is the usual prerequisite for achievement of competition. However, for a long time it has been thought that this principle of profit maximization can be replaced by natural selection. In an evolutionary model of an industry, where firms' outputs are chosen randomly, where entry occurs with no motivation and where exit occurs when a firm's wealth becomes negative, the first paper shows that the industry converges in probability to a perfectly competitive equilibrium as firms get infinitesimally small relative to the market, as the entry fixed costs get sufficiently …


"Sodomitical Practices": Representing Transgressive Masculinity In Fiction And Satire, 1660-1750, Cameron Mcfarlane Jan 1995

"Sodomitical Practices": Representing Transgressive Masculinity In Fiction And Satire, 1660-1750, Cameron Mcfarlane

Digitized Theses

This study examines the representation of the sodomite in a variety of texts from 1660 to 1750. Unlike most gay historiography of the Restoration and eighteenth century, the study does not begin with the assumption that the increased discursive presence of the sodomite during this period necessarily indicates the emergence of a proto-modern "homosexual" identity; rather, it seeks to uncover the range of meanings set in motion by the figure of the sodomite and to examine the way that the representation of this figure is implicated in the larger configurations of social ordering and control. At the same time, however, …


Exploration Of Partitioned State Tourism: The Example Of Partitioned China, Baodi Mao Jan 1995

Exploration Of Partitioned State Tourism: The Example Of Partitioned China, Baodi Mao

Digitized Theses

The European political state system has spread throughout the world and has become the predominant geo-political organization. However, the recent partitioning of states have generated a type of abnormal political entities: partitioned states. These partitioned states have serious implications for tourism development. Despite the uncertainty created by political strife and subdivision, many people continue to travel between partitioned states. Economic necessity, religious obligations, family ties, political negotiations, and pleasure are all relevant motivations driving the movement of people between these partitioned states. However, there is a substantial lack of systematic research on the movement of tourists between divided partitioned states. …


Salmon Aquaculture In Shetland And New Brunswick: A Comparative Study Of Resource Regimes Within A Moral Perspective, Craig Fergus Millar Jan 1995

Salmon Aquaculture In Shetland And New Brunswick: A Comparative Study Of Resource Regimes Within A Moral Perspective, Craig Fergus Millar

Digitized Theses

Development is a process of transformation within and among decision-making institutions. The oceans are a commons; the necessary institutions for resource management are organized within nation-state regimes and community-based regimes.;A morality is a framework of ethics governing participation in institutions and associated regimes. As social institutions, technology and property are moralities. Aquaculture, as new technology requiring the establishment of private property rights in a commons, is a development especially sensitive to the moral dimension.;Salmon aquaculturists in Shetland and New Brunswick use the same technology and exhibit very similar production profiles. Salmon farmers in Shetland have established themselves within a property …


The Perception Of Rhythm And Tempo Modulation In Music, Matthew Stratton Royal Jan 1995

The Perception Of Rhythm And Tempo Modulation In Music, Matthew Stratton Royal

Digitized Theses

Research is presented on the perception of rhythm, specifically, the detection of changing or "modulating" inter-onset intervals in simple musical stimuli. The types of changes of rhythmic patterns examined are "rhythm modulation" and "tempo modulation." These two terms are akin to the musician's concepts of agogics, rubato, accelerando and ritardando, all being common expressive devices in musical performance. Rhythm modulation occurs when an initially even or isochronous rhythm becomes increasingly more uneven. Tempo modulation occurs when the beat rate of a rhythm accelerates or decelerates.;Two approaches are adopted to elucidate how such modulating patterns might be perceived, a theoretical one …


Other Frontiers: Female Vagrants And Mother Outlaws In American Literature And Film Of The 1980s, Jacqui Marie Smyth Jan 1995

Other Frontiers: Female Vagrants And Mother Outlaws In American Literature And Film Of The 1980s, Jacqui Marie Smyth

Digitized Theses

The thesis examines female vagrant and outlaw figures in a selection of fictional texts produced in the 1980s. Using the idea of vagrancy in their characterizations of female protagonists, these texts revise persisting assumptions about women that are inherent in American culture. Beginning with a discussion of the reasons why women have been excluded, at least theoretically and ideologically, from a culture based on mobility, the thesis then considers two dominant and interrelated discourses in the American imagination--those of the frontier and of the myth of home--which are inescapable in any discussion of the American female outlaw and/or vagrant. This …


Tonality And Atonality In Alban Berg's Four Songs, Op2 (Austria), Gary Richard Tucker Jan 1995

Tonality And Atonality In Alban Berg's Four Songs, Op2 (Austria), Gary Richard Tucker

Digitized Theses

Alban Berg composed his Four Songs between 1908 and 1910; they were published in the latter year as his Op. 2. This was a critical period for Berg as for his mentor, Arnold Schoenberg, and his colleague Anton Webern. The latter two composers both later remembered 1908 as the year all three of them abandoned traditional tonality and began to write "atonal" music. There are problems, however, with the categories "tonal" and "atonal." Webern denied that the shift from one to the other really involved any radical change in how they handled pitch materials in their music. In Berg's Four …


Essays On R&D And Economic Growth, Jinli Zeng Jan 1995

Essays On R&D And Economic Growth, Jinli Zeng

Digitized Theses

This thesis consists of three essays on R&D and economic growth. The objective is to study the relationship between human capital accumulation, human capital allocation and R&D, on the one hand, and economic growth and welfare on the other.;The first essay, entitled "Capital Accumulation, R&D and Economic Growth", integrates two distinct categories of endogenous growth models (the capital-based models and the ideas-based models). A dynamic general equilibrium model is developed, in which both physical and human capital accumulation and investment in R&D are endogenously determined, and successful innovations not only discover new goods and destroy the old counterparts, but also …


Essays In Unemployment And Unemployment Insurance, Guang-Jia Zhang Jan 1995

Essays In Unemployment And Unemployment Insurance, Guang-Jia Zhang

Digitized Theses

This thesis examines several issues surrounding the causes of aggregate unemployment that relate to both individual work, rest, and search activities, and inter-industry labor reallocation process. On the other hand, this thesis also explores how heterogenous agents (employed and unemployed) react to a given unemployment insurance program as well as its welfare consequences within a general equilibrium search model.;The research in the first chapter is motivated by the three key features of the employment process in the U.S. economy: (1) job creation is procyclical, (2) job destruction is countercyclical, and (3) job creation is less volatile than job destruction. These …


The Putative Role Of Fatty Acids In The Activation Of Trehalose Synthesis In The Fat Body Of The Cockroach Periplaneta Americana L, Irshad Ali Jan 1995

The Putative Role Of Fatty Acids In The Activation Of Trehalose Synthesis In The Fat Body Of The Cockroach Periplaneta Americana L, Irshad Ali

Digitized Theses

Hypertrehalosemic hormones produced by the corpus cardiacum increase the concentration of several fatty acids in cockroach fat body trophocytes. The phospholipase A{dollar}\sb2{dollar} (PLA{dollar}\sb2){dollar} activator melittin has a similar effect. The fatty acids include palmitic, stearic, oleic and linoleic acid. The hormone mediated release of these fatty acids is blocked by the PLA{dollar}\sb2{dollar} inhibitors mepacrine and {dollar}\rho{dollar}-bromophenacyl bromide. These observations suggest that hormonal release of fatty acids, may be due to the activation of PLA{dollar}\sb2.{dollar};The increase in non-esterified fatty acids appears to be linked to the increase in trehalose efflux since sugar efflux is stimulated by stearic, oleic, linoleic and arachidonic …


Wind And Wave Loading On A Compliant Off-Shore Tower (Theory And Experiment), Mohammad Taghi Daneshvaran Jan 1995

Wind And Wave Loading On A Compliant Off-Shore Tower (Theory And Experiment), Mohammad Taghi Daneshvaran

Digitized Theses

The compliant tower is a slender jacket type structure which falls in the category of compliant platforms and is suited to deep water situations. Towers of this type resist the static loads through their stiffness while the first order wave loads are resisted primarily by inertia. Their typical first natural period is around 30 to 40 seconds and the second natural period is about 3 seconds so there would be little amplification of the response due to the first order wave forces. There is, however, dynamic amplification of the response due to the turbulent wind and nonlinear wave forces including …