Biodistribution And Method Validation Of Xylazine In A Mouse Model Using Liquid-Chromatography-Quadrupole-Time Of Flight Mass Spectrometry,
2025
Virginia Commonwealth University
Biodistribution And Method Validation Of Xylazine In A Mouse Model Using Liquid-Chromatography-Quadrupole-Time Of Flight Mass Spectrometry, Julia E. Perschbacher
Master of Science in Forensic Science Directed Research Projects
Xylazine is a nonopioid veterinary sedative and an α2 adrenergic receptor agonist. It emerged in the opioid epidemic as an adulterant of illicit fentanyl. As xylazine becomes more involved in fatal overdoses, it is relevant to elucidate its biodistribution post-exposure due to its exacerbation of adverse events, namely respiratory depression, as xylazine’s contributions to existing adverse effects of synthetic opioids is understudied. A bioanalytical method to quantify xylazine and select metabolites in tissue using LC-QToF was validated and applied to a preclinical mouse model in order to characterize xylazine’s biodistribution in whole blood and six tissues at a dose known …
Qualitative Method Validation Of Acid/Neutral Drugs Carisoprodol, Meprobamate, And Naproxen Using Liquid Chromatography-Tandem Mass Spectrometry,
2025
Virginia Commonwealth University
Qualitative Method Validation Of Acid/Neutral Drugs Carisoprodol, Meprobamate, And Naproxen Using Liquid Chromatography-Tandem Mass Spectrometry, Kate O. Martin
Master of Science in Forensic Science Directed Research Projects
Meprobamate, carisoprodol, and naproxen are acidic/neutral drugs widely prescribed for muscle relaxation and inflammatory conditions, with frequent detection in forensic toxicology casework due to extensive clinical use. A method to qualitatively evaluate these compounds was developed to unify acid/neutral drug screening. This study incorporated blank blood, antemortem blood, postmortem blood, urine, and liver homogenate as representative biological matrices. Method validation was conducted in accordance with ANSI/ASB Standard 036 for Forensic Toxicology, encompassing key parameters including limit of detection (LOD), endogenous interferences, potential interferences, carryover, processed sample stability, and ionization suppression/enhancement. The validation was performed using the internal standards carisoprodol-D7, meprobamate-D7, …
New Insights On Expert Opinion About Eyewitness Memory Research,
2025
Duke Law School
New Insights On Expert Opinion About Eyewitness Memory Research, Travis M. Seale-Carlisle, Adele Quigley-Mcbride, Jennifer E. F. Teitcher, William E. Crozier, Chad S. Dodson, Brandon L. Garrett
Faculty Scholarship
Experimental psychologists investigating eyewitness memory have periodically gathered their thoughts on a variety of eyewitness memory phenomena. Courts and other stakeholders of eyewitness research rely on the expert opinions reflected in these surveys to make informed decisions. However, the last survey of this sort was published more than 20 years ago, and the science of eyewitness memory has developed since that time. Stakeholders need a current database of expert opinions to make informed decisions. In this article, we provide that update. We surveyed 76 scientists for their opinions on eyewitness memory phenomena. We compared these current expert opinions to expert …
Should Decisions Of Independent Accountability Mechanisms Be Binding?,
2025
American University Washington College of Law
Should Decisions Of Independent Accountability Mechanisms Be Binding?, Lalanath De Silva, Giada Giacomini
Perspectives
In this essay, it is argued that IAMs should be empowered with binding decision-making authority to enhance their effectiveness and ensure that justice is served, and remedies delivered. This argument is supported by analyzing the right of access to justice. Further, this essay analyses existing mechanisms with binding decision-making power that have already been created or acknowledged by IFIs; these mechanisms include IFI administrative tribunals for employees, arbitration processes for commercial disputes, integrity related sanctions regimes, and the appeal bodies that hear access to information decisions. The IFIs’ embrace of binding decisions in these contexts demonstrates that nothing prevents IFIs …
An Overview Of Nagpra And The 2024 Revisions,
2025
The University Of Montana
An Overview Of Nagpra And The 2024 Revisions, Emily V. Owens-Barber
Graduate Student Theses, Dissertations, & Professional Papers
Section 11 of the National Museum of the American Indian Act (NMAIA) was added to public law in 1989. This required the Smithsonian Museum to repatriate any human remains or funerary objects associated with Native American Ancestry back to their tribes. In 1990, The Native American Graves Protection and Repatriation Act (NAGPRA) was added to federal legislation expanding on this section and requiring that every federally funded institution in the United States that held Native American Remains or funerary objects in their collection must follow this regulation to continue to receive federal funding. Nearly 33 years later in the autumn …
Jurisprudence Of Problem-Solving Courts: A Study Of Structure, Success, And Sociological Theory,
2025
University of Montana
Jurisprudence Of Problem-Solving Courts: A Study Of Structure, Success, And Sociological Theory, Lauren M. Boos
Graduate Student Theses, Dissertations, & Professional Papers
In response to the failures of mass incarceration and its disproportionate impact on marginalized communities, Problem-Solving Courts (PSCs) have emerged as alternatives to traditional prosecution. These courts employ therapeutic-informed and rehabilitative practices aimed at addressing the root causes of criminal behavior. While widely regarded as more effective than traditional courts, PSCs have developed largely without a formal theoretical foundation. This is notable given their alignment with Sociological Jurisprudence (SJ) and Therapeutic Jurisprudence (TJ), which view the legal system as a vehicle for promoting individual and community well-being.
Despite being celebrated as therapeutic innovations, PSCs often embody these principles unevenly. Using …
The Influence Of Honor Culture Ideology On Juror Decision Making,
2025
University of Northern Iowa
The Influence Of Honor Culture Ideology On Juror Decision Making, Aubrey K. Paschal
Dissertations and Theses @ UNI
Culture of honor is a system of cultural beliefs in which one’s honor is seen to be of the utmost importance (Nisbett & Cohen, 1996). Due to the importance of personal honor, defending one's honor could be seen as an adequate defense for crimes committed in the name of personal honor. This study examined the influence that honor culture ideology has on juror decision making. A total of 190 participants read a brief trial summary of either a crime in which the participants’ honor was threatened, or a crime that did not involve a threat to the defendant’s honor. The …
Religious Liberty, Public Accommodations, And Non-Discrimination: A Rapidly Emerging Injustice,
2025
Chapman University
Religious Liberty, Public Accommodations, And Non-Discrimination: A Rapidly Emerging Injustice, Gordon Babst
Political Science Faculty Books and Book Chapters
The decision in Burwell v. Hobby Lobby Stores, Inc., suggested to many that the scope of religious liberty was in a principled, logical way expanded to include free expression rights of corporate entities. It is concerning that many champion the decision as a basis for expanding religious exemptions to non-discrimination law as regards public accommodations, especially since the same reasoning that is being used with respect to the contemporary target of discrimination based in religious belief—American citizens who happen to be in a sexual minority—would apply by analogy, as it once did explicitly, to racial minorities. Unfortunately, given the …
“People [Are] Not Dying Because Officers Aren't Following Their Training. ‘It's Because They Are.”: The Construction Of Police De-Escalation Of Individuals In Mental Health Crises In Canadian Media,
2025
Wilfrid Laurier University
“People [Are] Not Dying Because Officers Aren't Following Their Training. ‘It's Because They Are.”: The Construction Of Police De-Escalation Of Individuals In Mental Health Crises In Canadian Media, Renée Haddock
Theses and Dissertations (Comprehensive)
Police are often assumed to be the "de facto" response to people in mental health crises. Contact between police and Canadians with mental illness and in crisis is routine and on the rise (Livingston, 2016). Police responses to these incidences have been criticized after several, highly publicized and tragic encounters between police and people in mental health crisis and the overrepresentation of people of colour in these instances. Media outlets determine which stories are prioritized, how they are framed, and which information to include or omit (Fawzi, 2018). Notably, public knowledge of police activities greatly impacts community perceptions of police …
Constructions Of Serial Killers And Victims: Analysis Of True Crime Docuseries,
2025
Wilfrid Laurier University
Constructions Of Serial Killers And Victims: Analysis Of True Crime Docuseries, Mira Dhaliwal
Theses and Dissertations (Comprehensive)
Stories of crime have consistently captured the attention of the public, with stories of heists, kidnappings and murder. The true crime genre receives enormous attention and serves for many as the primary source of crime knowledge, including who commits crime, how they commit crime and how law enforcement responds. Books and podcasts have been interrogated by researchers to understand the nature of the content but missing are the true crime documentaries and docuseries that have dominated streaming platforms in North America. The present study examined three true crime series about serial killers using social constructionism and social problems theory, and …
The Long-Term Psychological Effects Of Violent Crime On Victims: A Review Of Evidence And Supportive Interventions,
2025
Missouri State University
The Long-Term Psychological Effects Of Violent Crime On Victims: A Review Of Evidence And Supportive Interventions, Jayden E. Oleksyn-Lamb
Graduate Theses/Dissertations
This study utilizes anonymous survey data collected from 26 mental health professionals in various regions of Canada to understand which psychological disturbances are the most prevalent among victims of violent crime as well as which psychological interventions are most beneficial for treating violent crime victims. The data revealed that Post-Traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), anger, guilt, self-blame, and shame are each highly prevalent. Findings also revealed that certain therapeutic methods including Eye Movement Desensitization Reprocessing (EMDR), Supportive Counselling (SC), Progressive Relaxation (PR), Cognitive Reprocessing Therapy (CPT) and Cognitive Restructuring (CR) are associated with …
Victim-Offender Relationships And Their Influence On Crime Brutality And Sentencing Outcomes In Capital Homicide Cases,
2025
Missouri State University
Victim-Offender Relationships And Their Influence On Crime Brutality And Sentencing Outcomes In Capital Homicide Cases, Samantha Jane Trowbridge
Graduate Theses/Dissertations
This study examines capital murder cases in Missouri from 1976 to 2022 to explore how victim-offender relationships relate to both the brutality of homicides and sentencing outcomes. It addresses three main questions: What are the different types of victim-offender relationships in these cases, and how frequently does each type occur? How do these relationships influence sentencing outcomes, particularly the likelihood of receiving the death penalty versus life without parole? And which types of relationships are associated with the highest and lowest levels of brutality? The study uses official court records and applies a coding process to analyze relationship type, sentencing …
Women’S Pathways Into Prison: Cycles Of Harm,
2025
Edith Cowan University
Women’S Pathways Into Prison: Cycles Of Harm, Hilde Tubex, Natalie Gately
Research outputs 2022 to 2026
Women are a minority of the prison population, however their number is increasing at a faster rate than is the case for men. Interviews with 80 incarcerated women in Western Australian prisons revealed similar pathways commencing with adverse childhood experiences and subsequent areas of deprivation, which reverberated throughout their lives, leading to criminal behavior and imprisonment. Describing these cycles of harm, we argue that, in addressing the increase of women in prison, there is a need to move away from the individual “offender-focused” approach and look at the broader systemic context that lets women down and contributes to their criminalization.
From ‘Raise The Age’ To ‘Raise The Awareness’: How Knowledge Affects Public Opinion Of The Minimum Age Of Criminal Responsibility In Western Australia,
2025
Edith Cowan University
From ‘Raise The Age’ To ‘Raise The Awareness’: How Knowledge Affects Public Opinion Of The Minimum Age Of Criminal Responsibility In Western Australia, Suzanne Rock, Natalie Gately, Piero Moraro, James L. Finney
Research outputs 2022 to 2026
The minimum age of criminal responsibility (MACR) in Western Australia is 10 years old. While the negative impacts of early contact with justice systems have been well-documented and have resulted in calls to raise the age, research had not examined the public views of MACR in Western Australia. This article presents a novel examination of the knowledge and perceptions of the MACR with a sample of the West Australian public (n = 69). Findings from the semi-structured interviews revealed low levels of knowledge about the MACR, some reacted with surprise when provided with the information. Participants’ views shifted in that …
Impacto De La Pandemia De La Covid-19 En Las Familias De Los Jóvenes Universitarios De Las Poblaciones Rurales Mayas Del Estado De Yucatán,
2024
Universidad Autónoma de Yucatán
Impacto De La Pandemia De La Covid-19 En Las Familias De Los Jóvenes Universitarios De Las Poblaciones Rurales Mayas Del Estado De Yucatán, Jorge Atocha Pacheco Castro
Journal of Maya Heritage
Abstract. This study examines the impacts of the COVID-19 pandemic on the families of university students from rural Maya communities in Yucatán, Mexico. Utilizing an anthropological framework, the research highlights the interplay of structural vulnerabilities and cultural resilience. It explores how families navigated economic challenges, social interactions, and cultural practices amid the crisis. Key findings include the reliance on traditional subsistence practices such as small-scale agriculture and backyard farming, which provided a safety net during economic downturns. Socially, rural families reported lower stress levels and stronger communal bonds compared to their urban counterparts, owing to expansive living spaces and outdoor …
After Impunity: The Anti-Impunity Norm, The Colombian Special Jurisdiction For Peace, And The Future Of International Criminal Law,
2024
I-GMAP, Binghamton University
After Impunity: The Anti-Impunity Norm, The Colombian Special Jurisdiction For Peace, And The Future Of International Criminal Law, Max Pensky
Genocide Studies and Prevention: An International Journal
The predominance of international criminal law as a frontline response to atrocity crimes prioritizes the countering of impunity as an overarching goal. A corresponding “anti-impunity norm” identifies the legal punishment of individual perpetrators as a core requirement in legal responses to atrocities. This anti-impunity norm – the requirement to prosecute and punish – is also a legal obligation for state parties to the International Criminal Court. But the anti-impunity norm equates impunity’s opposite – accountability – with the imposition of legal punishment. This narrow interpretation of impunity places limits on states’ ability to craft context-specific responses to atrocities while also …
The Search For Unenumerated Fundamental Rights,
2024
CUNY Bernard M Baruch College
The Search For Unenumerated Fundamental Rights, Alina Sluzhyvenkova
Student Theses and Dissertations
There are certain rights that are explicitly enumerated in the Constitution, e.g., right to bear arms, right to free speech, right to a speedy and public trial. There are also rights that aren’t specifically written out but are nevertheless enjoyed by people nationwide. Rights that aren’t explicitly mentioned in the Constitution, but which are fundamental to are called the unenumerated rights. Unenumerated rights are just as important and can be derived from natural law, enumerated rights, the Ninth Amendment, precedents, judicial opinions, and substantive due process.
Substantive due process is a principle guaranteed by the Fifth and Fourteenth Amendments, which …
"Does Anyone Believe Me"?: The Traumatization Of Domestic Violence Survivors In The Criminal Justice System,
2024
Concordia University St. Paul
"Does Anyone Believe Me"?: The Traumatization Of Domestic Violence Survivors In The Criminal Justice System, Olivia Depalma
Master of Arts in Human Services
Survivors of domestic violence are often subject to chronic trauma as well as a heightened risk of injuries and mental health problems and disorders. The intention of the author is to focus on how trauma impacts a survivor’s ability to maneuver and interact with the criminal justice system (CJS). Prior studies have shown how survivor’s behaviors, usually the result of trauma, can lead to misconceived notions and beliefs in court officials and those involved in the CJS. Survivors will often face judgment, doubt, and criticism in the CJS, and this can impact their willingness to come forward, report the abuse, …
The Impact Of Adverse Childhood Experiences On Juvenile Delinquency,
2024
Minnesota State University Moorhead
The Impact Of Adverse Childhood Experiences On Juvenile Delinquency, Abigail Holmquist
Dissertations, Theses, and Projects
Abstract
Youth that have been exposed to Adverse Childhood Experiences (ACEs) are at a much higher risk of delinquent acts and involvement in the juvenile legal system. This study includes discussion on two studies of ACEs, conducted by Felitti et al. (2019) and Cronholm et al. (2015), reviews the impact of ACEs on juvenile delinquency in certain demographics, and includes case examples of how I have seen ACEs impact previous clients I had on my caseload. Discussion includes examples of how Social Control Theory and General Strain Theory apply to the relationship of ACEs and juvenile delinquency. Future research recommendations …
Testing Routine Activity Theory: Behavioural Pathways Linking Temperature To Crime,
2024
Rutgers University - Camden
Testing Routine Activity Theory: Behavioural Pathways Linking Temperature To Crime, Christopher Thomas, Jinuk Jeong, Kevin T. Wolff
Publications and Research
This study examines direct observations of outdoor routine activities to investigate the pathways through which temperatures shape crime. Daily administrative records of crime, weather, and outdoor activity were assembled from 2015 to 2019 in New York City. Mediation analysis (with bootstrapped standard errors) reveals that alterations in routine activities account for a statistically significant, yet modest, proportion of temperature’s relationship with homicides, shootings, assaults, larceny, and public consumption violations. The comparable mediation effects across violent and nonviolent crimes support routine activity theory as an explanatory framework for understanding temperature's impact on crime. The measures introduced here offer a novel approach …
