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Discrimination Of Monozygotic Twins Using Dna Methylation Levels Of One Cpg Site At Chromosome 3, Dino O. Robinson 2020 CUNY John Jay College

Discrimination Of Monozygotic Twins Using Dna Methylation Levels Of One Cpg Site At Chromosome 3, Dino O. Robinson

Student Theses

Conventional STR typing, commonly used in forensics for human identification, poses a problem in criminal cases and paternity disputes involving monozygotic (MZ) twins because they share identical DNA sequences. To date, no routine method is available in forensics to differentiate between individuals of MZ pairs. Recently, epigenetic methods measuring differential DNA methylation patterns have been applied to MZ twin differentiation. In this study, we investigated the potential to identify MZ twins using a previously identified DNA methylation site in chromosome 3, cg18562578, in a sample of 129 MZ and 37 dizygotic (DZ) twin pairs. We used bisulfite converted saliva DNA …


Discrimination Of Soil Organic Matter Using Nuclear Magnetic Resonance In Conjunction With Principal Component Analysis, Victoria G. Hsieh 2020 CUNY John Jay College

Discrimination Of Soil Organic Matter Using Nuclear Magnetic Resonance In Conjunction With Principal Component Analysis, Victoria G. Hsieh

Student Theses

The characterization of trace evidence is key to the field of forensic science. Trace evidence can take many forms, such as glass, fiber, and soil. Traditionally, forensic soil analysis has been painted as one of the more tedious applications, which conventionally studies the mineral composition of soil samples. In this study, we present another avenue of soil analysis that takes advantage of understudied factor of soil: soil organic matter (SOM). Using both proton (1H NMR) and carbon nuclear magnetic resonance (13C NMR) separately and applying principal component analysis (PCA) to both types of spectra, we sought …


Analysis Of Cannabinoids In Serum By Gc-Ms/Ms, Christie Cannarozzi 2020 CUNY John Jay College

Analysis Of Cannabinoids In Serum By Gc-Ms/Ms, Christie Cannarozzi

Student Theses

Due to recent changes in federal and state legislations, the availability and consumption of cannabis products have increased in the United States. The expanded use of recreational and medicinal cannabis products increases the importance of implementing sensitive and selective instrumental methods in toxicological laboratories, as legal implications may arise in forensic cases, such as driving under the influence of drugs (DUID). The purpose of this study was to perform a cross-validation for the quantitative analysis of cannabinoids (Δ9-tetrahydrocannabinol, cannabidiol, cannabinol, 11-hydroxy-Δ9-tetrahydrocannabinol, and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol) in serum by gas chromatography coupled to triple quadrupole tandem mass spectrometry (GCTQ). This method was fully …


Analyses Of Prosecutorial Power And Discretion In Mississippi: Evaluating Proposals To Address Misconduct And Abuse, Lucy Pruitt 2020 University of Mississippi

Analyses Of Prosecutorial Power And Discretion In Mississippi: Evaluating Proposals To Address Misconduct And Abuse, Lucy Pruitt

Honors Theses

This thesis seeks to create a policy proposal in order to address incidences of prosecutorial misconduct and abuse of discretion in the Mississippi criminal justice system. To do so, the author has summarized and analyzed seven criminal cases in which defendants have become victims of prosecutorial misconduct in order to shed light on the lack of prosecutorial accountability in the state’s criminal justice system. In an attempt to solve the problem, the author has developed a novel grading rubric in order to objectively and systematically analyze and evaluate previously proposed policy recommendations by legal experts and justice organizations. The successes …


Program And Proceedings: Nebraska Academy Of Sciences 1880–2020, 140th Anniversary Year, One Hundred-Thirtieth Annual Meeting, 2020 University of Nebraska - Lincoln

Program And Proceedings: Nebraska Academy Of Sciences 1880–2020, 140th Anniversary Year, One Hundred-Thirtieth Annual Meeting

Nebraska Academy of Sciences: Programs and Proceedings

No abstract provided.


Digital Forensic Readiness: An Examination Of Law Enforcement Agencies In The State Of Maryland, James B. McNicholas III 2020 Dakota State University

Digital Forensic Readiness: An Examination Of Law Enforcement Agencies In The State Of Maryland, James B. Mcnicholas Iii

Masters Theses & Doctoral Dissertations

Digital forensic readiness within the law enforcement community, especially at the local level, has gone mostly unexplored. As a result, a current lack of data exists that examines the digital forensic readiness of individual agencies, the possibility of proximity relationships, and correlations between readiness and backlogs. This quantitative, crosssectional research study sought to explore these issues by focusing on the state of Maryland. The study resulted in the creation of a digital forensic readiness scoring model that was then used to assign digital forensic readiness scores to thirty (30) of the one-hundred-forty-one (141) law enforcement agencies throughout Maryland. It was …


Digital Forensics Tools Integration, Alexander D. Kim 2020 Air Force Institute of Technology

Digital Forensics Tools Integration, Alexander D. Kim

Theses and Dissertations

As technology has become pervasive in our lives we record our daily activities both intentionally and unintentionally. Because of this, the amount of potential evidence found on digital media is staggering. Investigators have had to adapt and change their methods of conducting investigations to address the data volume. Digital forensics examiners current process consists of performing string searches to identify potential evidentiary items. Items of interest must then go through association, target comparison, and event reconstruction processes. These are manual and time consuming tasks for an examiner. This thesis presents a user interface that combines both the string searching capabilities …


The Effects Of The Evidence Preservation System (Eps) On The Storage Of Dna Samples, Devin Doyle 2020 Duquesne University

The Effects Of The Evidence Preservation System (Eps) On The Storage Of Dna Samples, Devin Doyle

Graduate Student Research Symposium

Storage of collected samples is a concern for all disciplines of forensic science. Without proper storage, especially DNA samples, the DNA will become unusable as it could become degraded, cross contaminated with other samples, etc. Much of the preliminary research revealed that there were very few studies on the storage of forensic samples regarding ideal protocols, let alone those that involved combining as many controlled storage aspects such as temperature, humidity, and UV exposure. This research focuses on the Evidence Preservation System (EPS) by Forensic Solutions, Inc., which is a controlled environment able to be programmed to control temperature and …


Review Of Fundamental To Know About The Future, Hannarae Lee 2020 Marywood University, U.S.A

Review Of Fundamental To Know About The Future, Hannarae Lee

International Journal of Cybersecurity Intelligence & Cybercrime

What we consider fundamental elements can be easily overlooked or perceived as facts without the process of empirical testing. Especially in the field of cybercrime and cybersecurity, there are more speculations regarding the prevalence and the scope of harm carried out by wrongdoers than empirically tested studies. To fill the void, three articles included in the current issue addresses empirical findings of fundamental concerns and knowledge in the field of cybercrime and cybersecurity.


Illegal Gambling And Its Operation Via The Darknet And Bitcoin: An Application Of Routine Activity Theory, Sinyong Choi, Kyung-Shick Choi, Yesim Sungu-Eryilmaz, Hee-Kyung Park 2020 Bridgewater State University

Illegal Gambling And Its Operation Via The Darknet And Bitcoin: An Application Of Routine Activity Theory, Sinyong Choi, Kyung-Shick Choi, Yesim Sungu-Eryilmaz, Hee-Kyung Park

International Journal of Cybersecurity Intelligence & Cybercrime

The Darknet and Bitcoins have been widely utilized by those who wish to anonymously perform illegal activities in cyberspace. Restricted in many countries, gambling websites utilize Bitcoin payments that allow users to freely engage in illegal gambling activities with the absence of a formal capable guardian. Despite the urgency and limited knowledge available to law enforcement regarding this issue, few empirical studies have focused on illegal gambling websites. The current study attempts to examine the characteristics and operations of online gambling websites on both the Darknet and Surface Web, which allow Bitcoin payments. The findings suggest that both websites on …


An Empirical Study To Determine The Role Of File-System In Modification Of Hash Value, Kumarshankar Raychaudhuri, M. George Christopher 2020 Bridgewater State University

An Empirical Study To Determine The Role Of File-System In Modification Of Hash Value, Kumarshankar Raychaudhuri, M. George Christopher

International Journal of Cybersecurity Intelligence & Cybercrime

In digital forensics, maintaining the integrity of digital exhibits is an essential aspect of the entire investigation and examination process, which is established using the technique of hashing. Lack of knowledge, while handling digital exhibits, might lead to unintentional alteration of computed hash, rendering the exhibit unacceptable in the court of Law. The hash value of a physical drive does not solely depend upon the data files present in it but also its file-system. Therefore, any change to the file-system might result in the change of the disk hash, even when the data files within it remain untouched. In this …


A Reverse Digital Divide: Comparing Information Security Behaviors Of Generation Y And Generation Z Adults, Scott M. Debb, Daniel R. Schaffer, Darlene G. Colson 2020 Bridgewater State University

A Reverse Digital Divide: Comparing Information Security Behaviors Of Generation Y And Generation Z Adults, Scott M. Debb, Daniel R. Schaffer, Darlene G. Colson

International Journal of Cybersecurity Intelligence & Cybercrime

How individuals conceptualize their accountability related to digital technology. There may also be age-based vulnerabilities resulting from personal perceptions about the importance of engaging in best-practices. However, age may not be as critical as experience when it comes to implementation of these behaviors. Using the Cybersecurity Behaviors subscale of the Online Security Behaviors and Beliefs Questionnaire (OSBBQ), this study compared the self-reported cybersecurity attitudes and behaviors across college-aged individuals from Generation Y and Generation Z. Data were derived from a convenience sample of predominantly African-American and Caucasian respondents (N=593) recruited from two public universities in Virginia, USA. Four of the …


Book Review: The Cyber Risk Handbook By Domenic Antonucci, Stanley Mierzwa 2020 Bridgewater State University

Book Review: The Cyber Risk Handbook By Domenic Antonucci, Stanley Mierzwa

International Journal of Cybersecurity Intelligence & Cybercrime

No abstract provided.


Investigating The Potential And Pitfalls Of Ev-Encapsulated Micrornas As Circulating Biomarkers Of Breast Cancer, Brian M. Moloney, Katie E. Gilligan, Doireann P. Joyce, Clodagh P. O'Neill, Killian P. O'Brien, Sonja Khan, Claire L. Glynn, Ronan M. Waldron, Ciarán M. Maguire, Emma Holian, Erin Naughton, Mohamed Elhadi, Andrea B. Grealish, Carmel Malone, Emma McDermott, Peter Dockery, Thomas Ritter, Adriele Prina-Mello, Michael J. Kerin, Róisín M. Dwyer 2020 National University of Ireland, Galway

Investigating The Potential And Pitfalls Of Ev-Encapsulated Micrornas As Circulating Biomarkers Of Breast Cancer, Brian M. Moloney, Katie E. Gilligan, Doireann P. Joyce, Clodagh P. O'Neill, Killian P. O'Brien, Sonja Khan, Claire L. Glynn, Ronan M. Waldron, Ciarán M. Maguire, Emma Holian, Erin Naughton, Mohamed Elhadi, Andrea B. Grealish, Carmel Malone, Emma Mcdermott, Peter Dockery, Thomas Ritter, Adriele Prina-Mello, Michael J. Kerin, Róisín M. Dwyer

Forensic Science Publications

Extracellular vesicles (EVs) shuttle microRNA (miRNA) throughout the circulation and are believed to represent a fingerprint of the releasing cell. We isolated and characterized serum EVs of breast tumour-bearing animals, breast cancer (BC) patients, and healthy controls. EVs were characterized using transmission electron microscopy (TEM), protein quantification, western blotting, and nanoparticle tracking analysis (NTA). Absolute quantitative (AQ)-PCR was employed to analyse EV-miR-451a expression. Isolated EVs had the appropriate morphology and size. Patient sera contained significantly more EVs than did healthy controls. In tumour-bearing animals, a correlation between serum EV number and tumour burden was observed. There was no significant relationship …


Potential Applications Of Microrna Profiling To Forensic Investigations, Claire L. Glynn 2020 University of New Haven

Potential Applications Of Microrna Profiling To Forensic Investigations, Claire L. Glynn

Forensic Science Publications

Within the forensic science community, there is a continued push to develop novel tools to aid in criminal investigations. microRNA (miRNA) analysis has been the focus of many researcher’s attention in the biomedical field since its discovery in 1993; however, the forensic application of miRNA analysis has only been suggested within the last 10 years and has been gaining considerable traction recently. The primary focus of the forensic application of miRNA analysis has been on body fluid identification to provide confirmatory universal analysis of unknown biological stains obtained from crime scenes or evidence items. There are, however, other forensic applications …


Effective Laundering Conditions For Ignitable Liquid Decontamination Of Fire Scene Clothing Used By The Bureau Of Alcohol, Tobacco, Firearms, And Explosives, Rebecca K. Whitney 2020 Virginia Commonwealth University

Effective Laundering Conditions For Ignitable Liquid Decontamination Of Fire Scene Clothing Used By The Bureau Of Alcohol, Tobacco, Firearms, And Explosives, Rebecca K. Whitney

Master of Science in Forensic Science Directed Research Projects

Ignitable liquids such as gasoline and diesel fuel are common accelerants encountered by Certified Fire Investigators (CFIs). These ignitable liquids can be identified by gas chromatography-mass spectroscopy; the presence of particular peaks in appropriate abundances and patterns indicates the presence of compounds found in ignitable liquids. The Bureau of Alcohol, Tobacco, Firearms, and Explosives (ATF) issues clothing to its CFIs for wear during fire scene investigation. Previous research has identified a method to decontaminate the tools used by CFIs, but no explicit protocol to decontaminate scene clothing has been determined. This study investigated the use of Tide Ultra Stain Release, …


Discrimination Of Colorless Fibers By Uv-Vis Microspectrophotometry And Microspectrofluorimetry, Kialani Killinger 2020 Virginia Commonwealth University

Discrimination Of Colorless Fibers By Uv-Vis Microspectrophotometry And Microspectrofluorimetry, Kialani Killinger

Master of Science in Forensic Science Directed Research Projects

Fiber evidence is frequently encountered in forensic casework, and part of a typical fiber analytical scheme involves the detailed study of the color and other physical properties, optical properties, and chemical composition of the fibers in question. Microspectrophotometry (MSP) is commonly used to provide objective color measurements of fibers, eliminating subjectivity that may be present in visual color examinations. MSP can produce color measurements over the ultraviolet (UV) and visible (VIS) regions of the electromagnetic spectrum, as well as emission spectra from fluorescence measurements. In this research, colorless fibers were analyzed by MSP, using both transmission measurements in the UV-VIS …


Analysis Of Pellet Patterns And Gsr Produced From Judge Taurus Revolvers, Donald Poon 2020 Virginia Commonwealth University

Analysis Of Pellet Patterns And Gsr Produced From Judge Taurus Revolvers, Donald Poon

Master of Science in Forensic Science Directed Research Projects

The Taurus Judge is a five-shot revolver designed to fire both 410 Bore shotshells and caliber 45 (Long) Colt cartridges. It is marketed as a self-defense firearm by Taurus. As of 2010, the Taurus Judge was “quickly becoming a popular personal defense firearm”.1 Although it has become somewhat popular, the Taurus Judge and its various models have not had many distance determination studies completed and there is still a dearth of information on how these handguns compare with shotguns when looking at range of fire determinations. This study focused on: how barrel length affected pellet spread patterns produced by …


Justice In Forensic Algorithms, Brandon L. Garrett 2020 Duke Law School

Justice In Forensic Algorithms, Brandon L. Garrett

Faculty Scholarship

No abstract provided.


The Costs And Benefits Of Forensics, Brandon L. Garrett 2020 Duke Law School

The Costs And Benefits Of Forensics, Brandon L. Garrett

Faculty Scholarship

Supreme Court Justice Louis Brandeis famously wrote that states can be laboratories for experimentation in law and policy. Disappointingly, however, the actual laboratories that states and local governments run are not a home for experimentation. We do not have adequate information about either the costs or the benefits of forensic testing or allocation of resources. Increased spending and expansion of crime laboratories has perversely accompanied growing backlogs. Poor quality control has resulted in a series of audits and even closures of crime laboratories. In response to these problems, however, some laboratories and some entire states have developed new approaches toward …


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