Emergent Tandemheart-Extracorporal Membrane Oxygenation For Refractory Ischemic Ventricular Arrhythmia,
2026
HCA Healthcare
Emergent Tandemheart-Extracorporal Membrane Oxygenation For Refractory Ischemic Ventricular Arrhythmia, Mukhtar Al-Saadi, Aswin Srinivasan, Mohammed Rajab, Alexander Rhodes, Negar Niknam, Pranav Loyalka
Gulf Coast Division GME Research Day 2026
No abstract provided.
Linker-Free Gold-Sputtered Tapered Optical Fiber Plasmonic Sensors For High-Sensitivity Refractive Index Detection In Microfluidic Platforms,
2026
Old Dominion University
Linker-Free Gold-Sputtered Tapered Optical Fiber Plasmonic Sensors For High-Sensitivity Refractive Index Detection In Microfluidic Platforms, Erem Ujah, Gymama Slaughter
Center for Bioelectronics Publications
Gold-sputtered tapered optical fiber (Au-TOF) sensors were developed for high-sensitivity refractive-index (RI) detection using aqueous glucose standards spanning 1.33–1.41 RIU (0–50% w/v). The sensors were fabricated using a reproducible workflow combining flame-brushing tapering, plasma surface preparation, and rotational magnetron sputtering, enabling azimuthally uniform gold coatings without the use of thiol or sulfur linker chemistries. Two sputtering durations (24 s and 30 s) were investigated to examine thickness-dependent plasmonic coupling and sensing performance. Optical measurements were conducted using a broadband supercontinuum source and compact spectrometer within a 20 µL microfluidic sensing chamber. Increasing glucose concentration produced a monotonic decrease in transmission …
Bridging The Gap: Why Circulating Micrornas Have Yet To Become Clinical Biomarkers For Endometriosis,
2026
Virginia Commonwealth University
Bridging The Gap: Why Circulating Micrornas Have Yet To Become Clinical Biomarkers For Endometriosis, Anisha Addepalli, Mary C. Boyes
UROP Posters
Endometriosis is a chronic inflammatory disorder in which endometrial-like tissue grows outside the uterus, leading to pelvic pain, infertility, and diagnostic delays due to the current reliance on invasive laparoscopy. Although imaging and hormonal assays offer limited accuracy in diagnosing the disease, circulating microRNAs (miRNAs) in arterial blood have emerged as a promising alternative method as noninvasive biomarkers because they regulate gene expression, reflect inflammatory and angiogenic pathways, and remain stable in circulation. I propose investigating miRNAs such as miR-17-5p, miR-451a, and the let-7 family because of their direct involvement in the regulation of processes such as cell proliferation, immune …
Proof-Of-Concept Development And Preclinical Evaluation Of A Microarray Patch Platform For Codelivery Of Multiple Broadly Neutralizing Antibodies For Hiv Prevention,
2026
Macon & Joan Brock Virginia Health Sciences at Old Dominion University
Proof-Of-Concept Development And Preclinical Evaluation Of A Microarray Patch Platform For Codelivery Of Multiple Broadly Neutralizing Antibodies For Hiv Prevention, M. Melissa Peet, Vivek Agrahari, Parbeen Singh, Lam Luong Hoai Nguyen, Louise A. Ouattara, Eun Sung Yang, Carolina Herrera, Amarendra Pegu, Theodore C. Pierson, Thanh D. Nguyen, Gustavo F. Doncel
CONRAD Publications
Broadly neutralizing antibodies (bnAbs) are advancing as a preventative or treatment option for HIV infection, but currently must be administered parenterally, typically as a large injection or infusion, an invasive method of delivery, especially for the pediatric population. Here, we present proof-of-concept data on a minimally invasive microneedle (MN) patch platform codelivering three bnAbs, PGT121, VRC07-523LS, and PGDM1400LS, from separate MN patch units or pixels. Each 1 cm² patch pixel, fabricated via solvent casting, contained similar to 2 mg of one bnAb. In ex vivo porcine skin tests, the MNs effectively penetrated the skin. When tested in vitro in PBS …
Tylenol Or Toradol? Iv Acetaminophen Vs. Parenteral Ketorolac For Prehospital Analgesia,
2026
HCA Healthcare
Tylenol Or Toradol? Iv Acetaminophen Vs. Parenteral Ketorolac For Prehospital Analgesia, Conrad Stallings, Kevin Crocker, Michael Wells, Nick Smith, Casey Patrick
Gulf Coast Division GME Research Day 2026
No abstract provided.
Beware Of Bears: Severe Hydronephrosis & Urinary Retention Hidden Behind A Uti,
2026
HCA Healthcare
Beware Of Bears: Severe Hydronephrosis & Urinary Retention Hidden Behind A Uti, Bjorn Sorensen, Victoria Jackson, Carissa Ford
Gulf Coast Division GME Research Day 2026
No abstract provided.
Tackling Tele Box Shortage Via Educational Initiative,
2026
HCA Healthcare
Tackling Tele Box Shortage Via Educational Initiative, Guntash Khasria, Bushra Ambreen
Gulf Coast Division GME Research Day 2026
No abstract provided.
Redo-Tavr Vs Tavr Explant Vs Redo-Savr: Comparative Outcomes In Failed Transcatheter Bioprostheses,
2026
HCA Healthcare
Redo-Tavr Vs Tavr Explant Vs Redo-Savr: Comparative Outcomes In Failed Transcatheter Bioprostheses, Yves Najm Mrad, Ahmad Al-Taweel, Bahaeddin Shabaneh
Gulf Coast Division GME Research Day 2026
No abstract provided.
Dexmedetomidine Versus Propofol For Reducing Emergence Delirium In Pediatric Anesthesia: A Scoping Review,
2026
University of Tennessee Health Science Center
Dexmedetomidine Versus Propofol For Reducing Emergence Delirium In Pediatric Anesthesia: A Scoping Review, Hannah Laxton Bsn, Rn, Hannah Mclain Bsn, Rn, Robert Mohr Bsn, Rn, Sarah Rocha Bsn, Rn, Laura Reed Dnp, Aprn, Fnp-Bc, Cne, Dwanye Accardo Dnp, Crna, Faana
Doctor of Nursing Practice Projects
Purpose/Background
Propofol is widely regarded as the standard anesthetic agent for preventing and treating emergence delirium, particularly in pediatric patients. Emergence delirium presents as postoperative agitation that may escalate to self-injurious behavior that can lead to disruption of critical lines or equipment. Since its approval in 1999, dexmedetomidine has gained attention for its sedative and sympatholytic properties, offering potential advantages over propofol. This study compares the postoperative effects of propofol and dexmedetomidine in reducing emergence delirium in pediatric surgical patients.
Methods
A scoping review was conducted using PRISMA guidelines to identify relevant literature published between 2000 and 2025. Databases searched …
Partial Molar Pregnancy With Extreme Elevation Of Quantitative Β-Hcg,
2026
Mercer University School of Medicine
Partial Molar Pregnancy With Extreme Elevation Of Quantitative Β-Hcg, Zachary Franklin, Amanda Royek, Kaitlyn Vu, Anthony Royek
South Atlantic Division GME Research Days 2026
No abstract provided.
Surgical Approach To Colon Resection With Colostomy Creation Influences Reversal Rates And Postoperative Outcomes: A Retrospective Longitudinal Analysis,
2026
HCA Healthcare
Surgical Approach To Colon Resection With Colostomy Creation Influences Reversal Rates And Postoperative Outcomes: A Retrospective Longitudinal Analysis, Benjamin Perkins, Ena Novakovic-Bennet, Salvatore Caleb Jerris, Alyssa Kozlowski, Andrew Schlussel
South Atlantic Division GME Research Days 2026
No abstract provided.
Identifying Relevant Covariates In Rna-Seq Analysis By Pseudo-Variable Augmentation,
2026
Old Dominion University
Identifying Relevant Covariates In Rna-Seq Analysis By Pseudo-Variable Augmentation, Yet Nguyen, Dan Nettleton
Mathematics & Statistics Faculty Publications
RNA-sequencing (RNA-seq) technology allows for the identification of differentially expressed genes, which are genes whose mean transcript abundance levels vary across conditions. In practice, RNA-seq datasets often include covariates that are of primary interest in addition to a set of covariates that are subject to selection. Some of these covariates may be relevant to gene expression levels, while others may be irrelevant. Ignoring relevant covariates or attempting to adjust for the effect of irrelevant covariates can compromise the identification of differentially expressed genes. To address this issue, we propose a variable selection method that uses pseudo-variables to control the expected …
Utilizing Machine Learning Techniques For Computer-Aided Covid-19 Screening Based On Clinical Data,
2026
The University of Texas at El Paso
Utilizing Machine Learning Techniques For Computer-Aided Covid-19 Screening Based On Clinical Data, Honglun Xu, Andrews T. Anum, Michael Pokojovy, Sreenath Chalil Madathil, Yuxin Wen, Md Fashiar Rahman, Tzu-Liang (Bill) Tseng, Scott Moen, Eric Walser
Mathematics & Statistics Faculty Publications
The COVID-19 pandemic has highlighted the importance of rapid clinical decision-making to facilitate the efficient usage of healthcare resources. Over the past decade, machine learning (ML) has caused a tectonic shift in healthcare, empowering data-driven prediction and decision-making. Recent research demonstrates how ML was used to respond to the COVID-19 pandemic. This paper puts forth new computer-aided COVID-19 disease screening techniques using six classes of ML algorithms (including penalized logistic regression, random forest, artificial neural networks, and support vector machines) and evaluates their performance when applied to a real-world clinical dataset containing patients’ demographic information and vital indices (such as …
Wearable Biosensors For Continuous Monitoring Of Chronic Kidney Disease: Materials, Biofluids, And Digital Health Integration,
2026
Old Dominion University
Wearable Biosensors For Continuous Monitoring Of Chronic Kidney Disease: Materials, Biofluids, And Digital Health Integration, Anupamaa Sivasubramanian, Shankara Narayanan, Gymama Slaughter
Center for Bioelectronics Publications
Chronic kidney disease (CKD) is a progressive and irreversible disorder affecting over 850 million individuals globally and is associated with significant morbidity, mortality, and healthcare burden. Conventional diagnostic approaches rely on intermittent laboratory measurements, including serum creatinine, estimated glomerular filtration rate (eGFR), and urinary albumin, which provide limited temporal resolution and fail to capture dynamic physiological changes. Recent advances in wearable biosensing technologies offer new opportunities for continuous, non-invasive monitoring of biochemical and physiological markers relevant to renal function. This review provides a comprehensive analysis of wearable biosensors for CKD monitoring, focusing on sensing mechanisms (electrochemical, optical, and field-effect transistor), …
Ai-Assisted Surface-Enhanced Raman Spectroscopy For Cardiovascular Diagnostics: From Plasmonic Materials To Clinical Translation,
2026
Old Dominion University
Ai-Assisted Surface-Enhanced Raman Spectroscopy For Cardiovascular Diagnostics: From Plasmonic Materials To Clinical Translation, Anju Joshi, Gymama Slaughter
Center for Bioelectronics Publications
Raman spectroscopy (SERS) has emerged as a powerful analytical technique, offering molecular fingerprint specificity and ultrasensitive detection of cardiac biomarkers. Recent advances in plasmonic nanostructures, surface functionalization strategies, and flexible sensing platforms have significantly improved the analytical performance of SERS-based biosensors. In parallel, the integration of artificial intelligence (AI) and machine learning has enabled robust interpretation of complex spectral datasets, facilitating automated biomarker classification and improved diagnostic accuracy in heterogeneous biological environments. Despite these advances, the field remains fragmented, with limited integration between nanomaterial design, biomarker selection, and data-driven analysis, and persistent challenges related to reproducibility, standardization, and clinical validation. …
Modulation Of Prussian Blue Redox Signaling By Molecular Imprinting For Reagent-Free Electrochemical Detection Of Emtricitabine,
2026
Old Dominion University
Modulation Of Prussian Blue Redox Signaling By Molecular Imprinting For Reagent-Free Electrochemical Detection Of Emtricitabine, Abdellatif Ait Lahcen, Gymama Slaughter
Center for Bioelectronics Publications
Reagent-free electrochemical sensors offer significant benefits for rapid, affordable point-of-care drug testing. In this study, we introduce a novel, reagent-free electrochemical sensor based on a molecularly imprinted polymer (MIP) specifically designed for the selective detection of Emtricitabine (FTC), a common antiretroviral used in HIV therapy. The sensor uses laser-induced graphene (LIG) electrodes, renowned for their high conductivity and porosity, ideal for electrochemical sensing. To enable reagent-free operation, the LIG surface was electrochemically coated with Prussian Blue, serving as a redox-active layer. Next, an MIP-PPy film was electropolymerized onto the Prussian Blue surface in the presence of FTC as a template, …
Gender, And Socioeconomic Status In School-Based Speech-Language Pathology Decision-Making For Adolescents With Traumatic Brain Injury: A Critically Appraised Topic,
2026
Long Island University
Gender, And Socioeconomic Status In School-Based Speech-Language Pathology Decision-Making For Adolescents With Traumatic Brain Injury: A Critically Appraised Topic, Geneva Renee Toledo
Selected Full-Text Master Theses 2021-
Purpose: Adolescents are at greater risk for traumatic brain injury (TBI), and TBI-related symptoms may contribute to disciplinary actions that increase their risk of entering the school-toconfinement pipeline. Given the disproportionate representation of racially marginalized male adolescents within this pipeline, this critically appraised topic (CAT) examined how race, gender, and socioeconomic status may influence school-based speech-language pathology (SLP) services and clinical decision-making following TBI. Method: A structured search of five electronic databases was conducted to identify studies examining speech-language pathologists’ (SLPs’) clinical decision-making and management of adolescents with TBI in relation to race, gender, and socioeconomic status. Relevant studies were …
Acute Aortic Dissection Masquerading As Testicular Torsion: A Case Report,
2026
Macon & Joan Brock Virginia Health Sciences at Old Dominion University
Acute Aortic Dissection Masquerading As Testicular Torsion: A Case Report, Bruce M. Lo, Megyn K. Christensen, Coral E. Byrns, Benjamin Chidester
Department of Emergency Medicine Faculty Publications
Introduction: Aortic dissection is a rare but life-threatening condition with a high mortality rate if diagnosis is delayed. Aortic dissection classically presents with sudden-onset, sharp pain in the chest or back. However, atypical presentations can also occur, which could lead to a delay in diagnosis.
Case Report: A patient initially presented to the emergency department (ED) with left testicular pain ongoing for several hours. On examination, he had tenderness in the left lower quadrant abdomen and left testicle. A testicular ultrasound revealed decreased blood flow to the left testicle, raising concern for testicular torsion. The patient was taken to the …
Minimizing Unnecessary Ttes For Pfo Evaluation In Stroke Patients,
2026
HCA Healthcare
Minimizing Unnecessary Ttes For Pfo Evaluation In Stroke Patients, Jeffrey Lesser, Salman Islam, Aneesha Shaju, Aarohi Parikh, Jonathan Nguyen, Marelle Montanez
Gulf Coast Division GME Research Day 2026
No abstract provided.
Mechanical-Medical Convergence In Heart Failure: Artificial Intelligence, Finite-Element Modeling, And 3d Printing For Diagnosis And Prognosis,
2026
Dhaka Medical College and Hospital
Mechanical-Medical Convergence In Heart Failure: Artificial Intelligence, Finite-Element Modeling, And 3d Printing For Diagnosis And Prognosis, Quazi Noor E. Sabrina, Quazi Md Zobaer Shah, Quazi Noor E. Sohela, Md Mahabub Hasan Mousum, Md. Moyeen Uddin Chisty, Quazi Md. Akbar Shah
Mechanical & Aerospace Engineering Faculty Publications
Heart failure remains a leading cause of global morbidity and mortality, yet routine clinical indices often miss the regional biomechanical disturbances that drive progression and shape treatment response. This State-of-the-Art review examines how finite-element (FE) modeling, additive manufacturing, and artificial intelligence (AI) are converging to improve the diagnosis, phenotyping, procedural planning, and prognostic assessment of heart failure (HF). Although these technologies have matured in structural heart disease and transcatheter intervention research, their greatest translational potential may lie in HF, where patient-specific ventricular remodeling, myocardial stress–strain heterogeneity, valve-ventricular coupling, and device-tissue interaction are incompletely captured by conventional clinical indices. We synthesize …
