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Race/Ethnicity And Morbidity/Mortality In Laparoscopic Cholecystectomy: 2016 Usa Study, Victorien Meray, Rupa Seetharamaiah 2023 HCA Healthcare

Race/Ethnicity And Morbidity/Mortality In Laparoscopic Cholecystectomy: 2016 Usa Study, Victorien Meray, Rupa Seetharamaiah

East Florida Division GME Research Day 2023

Background: Social determinants of health, such as race and ethnicity, can have a significant impact on people's health and well-being. People of color are more likely to experience poverty, lack of access to healthcare, and discrimination, which can lead to worse health outcomes. Laparoscopic cholecystectomy is a surgical procedure to remove the gallbladder. It is the most common gastrointestinal surgery performed in the United States. In this study, we sought to determine if there is an association between race/ethnicity and morbidity/mortality in adult patients undergoing laparoscopic cholecystectomy.

Methods: We conducted a non-concurrent cohort study of patients over 18 years old …


Giant Mesenchymal Hepatic Hamartomas With Adrenal Involvement Precipitating Respiratory Failure: A Myxomatous Mystery In A 3 Month Old, Ali Yasback, Abid Ulhaque, Tushar Chandra, Sandor Szilagyi 2023 HCA Healthcare

Giant Mesenchymal Hepatic Hamartomas With Adrenal Involvement Precipitating Respiratory Failure: A Myxomatous Mystery In A 3 Month Old, Ali Yasback, Abid Ulhaque, Tushar Chandra, Sandor Szilagyi

West Florida Division GME Research Day 2023

No abstract provided.


Comparing 30-Day Outcomes Of Open Versus Endovascular Revascularization For Chronic Limb-Threatening Ischemia, David Kosoy, Waseem Wahood 2023 HCA Healthcare

Comparing 30-Day Outcomes Of Open Versus Endovascular Revascularization For Chronic Limb-Threatening Ischemia, David Kosoy, Waseem Wahood

East Florida Division GME Research Day 2023

Abstract: Chronic limb-threatening ischemia (CLTI) is a serious condition that can lead to amputation and even death. Open and endovascular revascularization are two common treatment options for CLTI, but the optimal treatment approach remains controversial. This study compared the 30-Day outcomes of open and endovascular revascularization using data from the National Surgical Quality Improvement Program (NSQIP) database. The study included 6,780 patients who underwent open bypass with saphenous vein, 4,201 patients who underwent open bypass with alternative conduit, and 8,887 patients who underwent endovascular intervention. Compared to open bypass with saphenous vein, endovascular intervention was associated with a higher rate …


Comparing The Expression Of Er, Pr, Her-2 Between Initial Biopsy And Excision Specimens In Invasive Breast Carcinoma Cases. Is There A Need For Universal Repeat Testing?, Gul Wymer, Astrid Sacasa, Susana Ferra 2023 HCA Healthcare

Comparing The Expression Of Er, Pr, Her-2 Between Initial Biopsy And Excision Specimens In Invasive Breast Carcinoma Cases. Is There A Need For Universal Repeat Testing?, Gul Wymer, Astrid Sacasa, Susana Ferra

East Florida Division GME Research Day 2023

BACKGROUND: The current College of American Pathologist (CAP) recommendation is that breast biomarkers Estrogen (ER), Progesterone (PR) and HER2 neu (Her2) testing be done on all primary invasive breast carcinomas and on recurrent or metastatic tumors with the aim to identify patients that will benefit from hormonal treatment or anti-Her2 therapy. Repeat testing on a subsequent specimen is not usually indicated unless results appear discordant with the histopathologic findings. The objective of the current study was to evaluate the need of adopting universal reflex re-testing of breast biomarkers in subsequent excision specimens. The rationale behind this study was based upon …


Rare Case Of Chylopericardium Status Post Coronary Artery Bypass Graft, Hytham Rashid, Harris R. Khawaja, Ashley Charales, Essam Girgawy, Ramesh Kesavan, Michael Daniel 2023 HCA Healthcare

Rare Case Of Chylopericardium Status Post Coronary Artery Bypass Graft, Hytham Rashid, Harris R. Khawaja, Ashley Charales, Essam Girgawy, Ramesh Kesavan, Michael Daniel

Gulf Coast Division GME Research Day 2023

No abstract provided.


Racial Disparities In Electroconvulsive Therapy Utilization 2016 To 2021, Steven Sprenger, Alexandra Koumtchev, Gerard Corsi, Natalie Hurlock 2023 HCA Healthcare

Racial Disparities In Electroconvulsive Therapy Utilization 2016 To 2021, Steven Sprenger, Alexandra Koumtchev, Gerard Corsi, Natalie Hurlock

TriStar Division Research Day 2023

No abstract provided.


Which Patients Are More Likely To Require Postoperative Inpatient Rehabilitation After Operative Intervention Of Traumatic Hip Fractures?, Daniel Lynch, Andrew Romero, Peter Zeblisky, Kyle Mahoney, Huazhi Liu, Darwin Ang 2023 HCA Healthcare

Which Patients Are More Likely To Require Postoperative Inpatient Rehabilitation After Operative Intervention Of Traumatic Hip Fractures?, Daniel Lynch, Andrew Romero, Peter Zeblisky, Kyle Mahoney, Huazhi Liu, Darwin Ang

North Florida Division GME Research Day 2023

No abstract provided.


Factors Contributing To Ventilator Dependent Days In Covid-19, Isaac Ginsberg, Samantha Eteve, Bryan Lunt, Kenneth Krell 2023 HCA Healthcare

Factors Contributing To Ventilator Dependent Days In Covid-19, Isaac Ginsberg, Samantha Eteve, Bryan Lunt, Kenneth Krell

Continental, MidAmerica, & Mountain Divisions GME Research Day 2023

No abstract provided.


Stones Cause Pediatric Moans Too: A Case Of Ureterolithiasis With Classic Sonographic Artifacts, Samantha Stoner, Courtney Mariner, Russ Richardson, Casey Wilson 2023 HCA Healthcare

Stones Cause Pediatric Moans Too: A Case Of Ureterolithiasis With Classic Sonographic Artifacts, Samantha Stoner, Courtney Mariner, Russ Richardson, Casey Wilson

South Atlantic Division GME Research Day 2023

No abstract provided.


Using Ultrasound To Assist Neonatal Lumbar Puncture: A How To Guide, Samantha Stoner, Tram-Anh Huynh, Casey Wilson 2023 HCA Healthcare

Using Ultrasound To Assist Neonatal Lumbar Puncture: A How To Guide, Samantha Stoner, Tram-Anh Huynh, Casey Wilson

South Atlantic Division GME Research Day 2023

No abstract provided.


Stone-Containing Meckel’S Diverticulitis As A Mimic Of Acute Appendicitis, Justin Denny, David Pardue 2023 HCA Healthcare

Stone-Containing Meckel’S Diverticulitis As A Mimic Of Acute Appendicitis, Justin Denny, David Pardue

South Atlantic Division GME Research Day 2023

No abstract provided.


Illicit Drug Use Patterns In Myrtle Beach, S.C. From 2017-2022, Michelle Fowler, Mark Plexousakis, Meg Riley, Blaine Rourke, Erin Artigiani, Amy Billing, Margaret Hsu, Ebonie Massey, Eric Wish 2023 HCA Healthcare

Illicit Drug Use Patterns In Myrtle Beach, S.C. From 2017-2022, Michelle Fowler, Mark Plexousakis, Meg Riley, Blaine Rourke, Erin Artigiani, Amy Billing, Margaret Hsu, Ebonie Massey, Eric Wish

South Atlantic Division GME Research Day 2023

No abstract provided.


Sonographic Measurements Of Inferior Vena Cava Collapsibility In Recreational Divers, David Pardue, Brandon Bowers, Scott Chewning, Casey Wilson 2023 HCA Healthcare

Sonographic Measurements Of Inferior Vena Cava Collapsibility In Recreational Divers, David Pardue, Brandon Bowers, Scott Chewning, Casey Wilson

South Atlantic Division GME Research Day 2023

No abstract provided.


Precision Medicine Approach To Alzheimer’S Disease: Rationale And Implications, Dale E. Bredesen, Kat Toups, Ann Hathaway, Deborha Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, Sharon Hausman-Cohen, Mouna Attarha, Won Jong Chwa, Alexei Kurakin, Michael Jarrett 2023 University of California, Los Angeles

Precision Medicine Approach To Alzheimer’S Disease: Rationale And Implications, Dale E. Bredesen, Kat Toups, Ann Hathaway, Deborha Gordon, Henrianna Chung, Cyrus Raji, Alan Boyd, Benjamin D. Hill, Sharon Hausman-Cohen, Mouna Attarha, Won Jong Chwa, Alexei Kurakin, Michael Jarrett

University Faculty and Staff Publications

The neurodegenerative disease field has enjoyed extremely limited success in the development of effective therapeutics. One potential reason is the lack of disease models that yield accurate predictions and optimal therapeutic targets. Standard clinical trials have pre-determined a single treatment modality, which may be unrelated to the primary drivers of neurodegeneration. Recent proof-of-concept clinical trials using a precision medicine approach suggest a new model of Alzheimer’s disease (AD) as a chronic innate encephalitis that creates a network insufficiency. Identifying and addressing the multiple potential contributors to cognitive decline for each patient may represent a more effective strategy. Here we review …


Evaluating Hpv Vaccination Adherence Amongst Teenagers Ages 12-18, Jade Vo, Myah Mukes, Kenya Nelson, Joye' Thomas, Laura Reed, Sharon Little 2023 University of Tennessee Health Science Center

Evaluating Hpv Vaccination Adherence Amongst Teenagers Ages 12-18, Jade Vo, Myah Mukes, Kenya Nelson, Joye' Thomas, Laura Reed, Sharon Little

Doctor of Nursing Practice Projects

Human papillomavirus (HPV) is a sexually transmitted infection that can cause genital warts and different cancers. According to the CDC, 85% of people will get an HPV infection in their lifetime. HPV infections have decreased significantly since the implementation of the HPV vaccine. Data has shown 90% of cancers caused by HPV can be prevented with administration of HPV vaccination. Current guidelines recommend vaccination administration as early as 9 years of age. This quality improvement project will evaluate HPV vaccination rates amongst teenagers ages 12-18.


Screening For Social Determinants Of Health In Children With Attention-Deficit/Hyperactivity Disorder, Sarah L. Carter MSN, APRN, CPNP-PC, Ronald Espinal MD, Toni Whitaker MD, Sally Humphrey DNP, APRN, CPNP-PC 2023 University of Tennessee Health Science Center

Screening For Social Determinants Of Health In Children With Attention-Deficit/Hyperactivity Disorder, Sarah L. Carter Msn, Aprn, Cpnp-Pc, Ronald Espinal Md, Toni Whitaker Md, Sally Humphrey Dnp, Aprn, Cpnp-Pc

Doctor of Nursing Practice Projects

Purpose/Background

Increased social determinants of health (SDoH) are associated with poorer health outcomes and decreased treatment compliance. Addressing SDoH can be associated with increased treatment compliance, although currently there is no standard for completing SDoH screening. The WE CARE screening tool is a validated screen that asks about 6 SDoH and whether the family is interested in assistance if the screen is positive. The purpose of this project was to implement the use of the WE CARE screening tool for patients with attention deficit hyperactivity disorder (ADHD) at follow-up visits.

Methods

From October 17, 2022 through November 22, 2022, charts …


An Explainable Deep Learning Prediction Model For Severity Of Alzheimer's Disease From Brain Images, Godwin O. Ekuma 2023 Missouri State University

An Explainable Deep Learning Prediction Model For Severity Of Alzheimer's Disease From Brain Images, Godwin O. Ekuma

Graduate Theses/Dissertations

Deep Convolutional Neural Networks (CNNs) have become the go-to method for medical imaging classification on various imaging modalities for binary and multiclass problems. Deep CNNs extract spatial features from image data hierarchically, with deeper layers learning more relevant features for the classification application. The effectiveness of deep learning models are hampered by limited data sets, skewed class distributions, and the undesirable "black box" of neural networks, which decreases their understandability and usability in precision medicine applications. This thesis addresses the challenge of building an explainable deep learning model for a clinical application: predicting the severity of Alzheimer's disease (AD). AD …


Research Model Applications In The Investigation Of Vascular Disease Treatments, Alex Anthony Dangler 2023 University of South Dakota

Research Model Applications In The Investigation Of Vascular Disease Treatments, Alex Anthony Dangler

Dissertations and Theses

Cardiovascular disease (CVD) is a pressing global health issue with significant socioeconomic consequences. Within the spectrum of CVDs, peripheral artery disease (PAD) and aortic disease necessitate the development of effective and safe treatments. To achieve this, various research models are employed to investigate molecular mechanisms of cells, understand cellular interactions in vascular diseases, assess biocompatibility, and test and evaluate medical devices. This dissertation examines research models and their applications in the advancement of treatments for vascular diseases. For the evaluation of liposome delivery systems in PAD, an ApoE-/- cellular mouse model was employed to investigate the cellular uptake of liposomes …


Patient Frailty: A Review, Lakshmi Sailaja Kodavati 2023 Harrisburg University of Science and Technology

Patient Frailty: A Review, Lakshmi Sailaja Kodavati

Dissertations and Theses

According to Geriator (2011), frailty is a common clinical syndrome in older adults that carries an increased risk for poor health outcomes such as falls, incident disability, hospitalization, and mortality. An operational definition of frailty is the existence of at least three out of five observable criteria indicating compromised energetics: low grip strength; low energy; slowed walking speed; low physical activity; and unintentional weight loss (Fried, et al. 2001).

According to Dubois and Charpillet (2017), most transitions into frailty are due to unintentional weight loss which, in turn, impacts gait performance and subsequent general mobility. In this literature review, the …


Evaluation Of Cold Atmospheric Plasma For The Decontamination Of Flexible Endoscopes, R. C. Hervé, Michael G. Kong, Sudhir Bhatt, Hai-Lan Chen, E. E. Comoy, J-P. Deslys, T. J. Secker, C. W. Keevil 2023 Old Dominion University

Evaluation Of Cold Atmospheric Plasma For The Decontamination Of Flexible Endoscopes, R. C. Hervé, Michael G. Kong, Sudhir Bhatt, Hai-Lan Chen, E. E. Comoy, J-P. Deslys, T. J. Secker, C. W. Keevil

Bioelectrics Publications

Background: Despite adherence to standard protocols, residues including live microorganisms may remain on the various surfaces of reprocessed flexible endoscopes. Prions are infectious proteins notoriously difficult to eliminate.

Aim: We tested the potential of cold atmospheric plasma (CAP) for the decontamination of flexible endoscope various surfaces, measuring total proteins and prion-residual infectivity as an indicator of efficacy.

Methods: New PTFE endoscope channels and metal test surfaces spiked with test soil or prion-infected tissues were treated using different CAP-generating prototypes. Surfaces were then examined for the presence of residues using very sensitive fluorescence epi-microscopy. Prion residual infectivity was determined using the …


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