Analytical, Diagnostic and Therapeutic Techniques and Equipment Commons^™

Does The Osteopathic Pedal Pump Reduce Lower Limb Volume In Healthy Subjects?, Jill S. Adams, Sahil H. Parikh, Brandon J. Goodwin, Donald R. Noll

Rowan-Virtua School of Osteopathic Medicine Departmental Research

CONTEXT: Lymphatic treatments are gentle and passive techniques believed to enhance movement of lymph back into the central circulatory system. Animal studies provide supportive evidence, yet there are few studies in humans.

OBJECTIVES: The aim of this study is to investigate whether the osteopathic pedal pump protocol reduces volume in the lower limbs of healthy subjects.

METHODS: A total of 30 first- and second-year medical students were recruited. Subjects were excluded from participating if they had acute asthma, chronic obstructive pulmonary disease (COPD), congestive heart failure, active infections, fractures of the lower extremities, or metastatic cancer. A within-subjects study design …

Development Of Potent Nanosized Carbonic Anhydrase Inhibitor For Targeted Therapy Of Hypoxic Solid Tumors, Ekram Hany Mohamed, Wagdy M. Eldehna,, Mahmoud A. El Hassab, Nahla A. Abdelshafi,

Pharmacy

Overexpression of two carbonic anhydrase (CA) isoforms, CA IX and XII, in several hypoxic solid tumors provides an extracellular hypoxic microenvironment, interferes with extra- and intracellular pH regulation, thus favoring hypoxic tumor cell survival, proliferation and metastasis. In the current study, a selective inhibitor for human CA isoforms IX and XII (isatin-bearing sulfonamide, WEG-104), was incorporated into nanosized spherical niosomes at high encapsulation efficiency to allow for an enhanced and sustained antitumor activity. In vivo, administration of WEG-104 that is either free (10 mg/kg) or loaded into niosomes (5 mg/kg) into a mice model of Ehrlich ascites solid tumor resulted …

Magnetic Resonance Imaging-Derived Microvascular Perfusion Modeling To Assess Peripheral Artery Disease, Olga A. Gimnich, Tatiana Belousova, Christina M. Short, Addison A. Taylor, Vijay Nambi, Joel D. Morrisett, Christie M. Ballantyne, Jean Bismuth, Dipan J. Shah, Gerd Brunner

School of Medicine Faculty Publications

BACKGROUND: Computational fluid dynamics has shown good agreement with contrast-enhanced magnetic resonance imaging measurements in cardiovascular disease applications. We have developed a biomechanical model of microvascular perfusion using contrast-enhanced magnetic resonance imaging signal intensities derived from skeletal calf muscles to study peripheral artery disease (PAD). METHODS AND RESULTS: The computational microvascular model was used to study skeletal calf muscle perfusion in 56 in-dividuals (36 patients with PAD, 20 matched controls). The recruited participants underwent contrast-enhanced magnetic resonance imaging and ankle-brachial index testing at rest and after 6-minute treadmill walking. We have determined associations of microvascular model parameters including the transfer …

Impact Of Perioperative Dexamethasone On Hospital Length Of Stay And Glycemic Control In Patients With Type 2 Diabetes Undergoing Total Hip Arthroplasty, Vanessa Williams, Mohammad J. Uddin Ansari, Amruta Jaju, Stacey Ward, Daniel O'Keefe, Jumana Abdelkarim, Nicole Montes, Ula Tarabichi, Albert Botchway, Michael G. Jakoby Iv

Journal of Patient-Centered Research and Reviews

Purpose: This study aimed to evaluate effects of perioperative dexamethasone on hospital length of stay (LOS) and glycemic control for patients with type 2 diabetes mellitus undergoing total hip arthroplasty (THA).

Methods: We performed retrospective case review of THA performed in adults (≥ 18 years old) with type 2 diabetes at Springfield Memorial Hospital (Springfield, IL) immediately before (2013), during (2014), and after (2015) publication of consensus guidelines for use of perioperative dexamethasone. Hospital LOS was the primary endpoint. Capillary blood glucose by hospital day, proportion of patients treated with insulin, and median insulin dose by hospital day …

Estimating Dementia Risk In An African American Population Using The Dctclock, Marissa Ciesla, Jeff Pobst, Joyce Gomes-Osman, Melissa Lamar, Lisa L Barnes, Russell Banks, Ali Jannati, David Libon, Rodney Swenson, Sean Tobyne, David Bates, John Showalter, Alvaro Pascual-Leone

Rowan-Virtua School of Osteopathic Medicine Departmental Research

The prevalence of Alzheimer's disease (AD) and related dementias (ADRD) is increasing. African Americans are twice as likely to develop dementia than other ethnic populations. Traditional cognitive screening solutions lack the sensitivity to independently identify individuals at risk for cognitive decline. The DCTclock is a 3-min AI-enabled adaptation of the well-established clock drawing test. The DCTclock can estimate dementia risk for both general cognitive impairment and the presence of AD pathology. Here we performed a retrospective analysis to assess the performance of the DCTclock to estimate future conversion to ADRD in African American participants from the Rush Alzheimer's Disease Research …

Therapeutic Approaches For Chronic Hepatitis C: A Concise Review, Allah Nawaz, Azhar Manzoor, Saeed Ahmed, Naveed Ahmed, Waseem Abbas, Mushtaq Ahmad Mir, Muhammad Bilal, Alisha Sheikh, Saleem Ahmad, Ishtiaq Jeelani, Takashi Nakagawa

School of Medicine Faculty Publications

Hepatitis C virus (HCV) infection is a significant global health concern, prompting the need for effective treatment strategies. This in-depth review critically assesses the landscape of HCV treatment, drawing parallels between traditional interferon/ribavirin therapy historically pivotal in HCV management and herbal approaches rooted in traditional and complementary medicine. Advancements in therapeutic development and enhanced clinical outcomes axis on a comprehensive understanding of the diverse HCV genome, its natural variations, pathogenesis, and the impact of dietary, social, environmental, and economic factors. A thorough analysis was conducted through reputable sources such as Science Direct, PubMed, Scopus, Web of Science, books, and dissertations. …

Community Risks For Sars-Cov-2 Infection Among Fully Vaccinated Us Adults By Rurality: A Retrospective Cohort Study From The National Covid Cohort Collaborative, Alfred Jerrod Anzalone, Jing Sun, Amanda J. Vinson, William H. Beasley, William B. Hillegass, Kimberly Murray, Brian M. Hendricks, Melissa Haendel, Carol Reynolds Geary, Kristina L. Bailey, Corrine K. Hanson, Lucio Miele, Ronald Horswell, Julie A. Mcmurry, J. Zachary Porterfield, Michael T. Vest, H. Timothy Bunnell, Jeremy R. Harper, Bradley S. Price

School of Medicine Faculty Publications

Background While COVID-19 vaccines reduce adverse outcomes, post-vaccination SARS-CoV-2 infection remains problematic. We sought to identify community factors impacting risk for breakthrough infections (BTI) among fully vaccinated persons by rurality. Methods We conducted a retrospective cohort study of US adults sampled between January 1 and December 20, 2021, from the National COVID Cohort Collaborative (N3C). Using Kaplan-Meier and Cox-Proportional Hazards models adjusted for demographic differences and comorbid conditions, we assessed impact of rurality, county vaccine hesitancy, and county vaccination rates on risk of BTI over 180 days following two mRNA COVID-19 vaccinations between January 1 and September 21, 2021. Additionally, …

Pmh Connect, English (Greyscale For Printing), Sara W. Moyer, Patricia Kinser

School of Nursing Publications

Mental health related symptoms and associated experiences in the perinatal period present challenges, particularly regarding identification and appropriate management. Perinatal Mental Health (PMH) screening occurs in clinical settings on a more regular basis than ever before thanks to validated screening measures used at perinatal visits; however, pregnant and parenting individuals report several concerns when completing these screeners and providers report barriers in addressing resultant findings. To address barriers and enhance the PMH screening experience, this team of clinicians and researchers propose a tool – the PMH Connect: a Perinatal Mental Health Screening Connection, Education, and Decision Aid – to be …

Exploring The Transition From General Ultrasound To Veterinary Ultrasound: Challenges And Opportunities, Juliette Myers, Kali Foltz, Emily Downs, Shaun Mcnamara

Student Research Poster Presentations 2023

Student Researchers: Juliette Myers, Kali Foltz

Interviewed Person: Emily Downs M.Ed., RDMS, RVT, RDCS, RT

Internship Mentor: Shaun McNamara, RDMS, AB, BR, OB/GYN, RVT, VT, St. Luke's Hospital, Monroe Campus, Stroudsburg, PA

The similarities, differences, and challenges of transitioning from general to veterinary ultrasound were explored through an interview and literary review. An interview was conducted with an experienced general and veterinary sonographer, Emily Downs. After the interview was completed, a literary review was conducted as evidence for the information received from the interview. The interview and research provided great information and detail on the transition process, what a sonographer …

Effects Of Nurse-Patient Relationship On Mental Health Patients’ Medication Adherence/Healthcare Outcome, April Monica Magbual

Nursing | Senior Theses

Background and Significance: Medication adherence among mentally ill patients (MIP) is a significant issue which require extra support & guidance to encourage better recovery. Administering medication is a critical role of nurses that must be performed effectively and appropriately, especially for MIPs.

Literature Review and Gap in the Literature: There is insufficient research exploring NPR and medication adherence specifically for MIPs. Participants’ cultural variations, age range, specific interventions & economic factors influencing medication compliance are missing. The current study aims to explore strategies that nurses can implement during patient interaction in the hospital setting.

Study Design and Method: A qualitative …

Assessment Of Patient And Surgeon Perception On Prophylactic Mesh: A Standard Gamble, Kayla Nguyen, Duyen Quach, Niharika Neela, Nicole Lyons, Oscar Olavarria

Gulf Coast Division GME Research Day 2023

No abstract provided.

Implementing Point-Of-Care Ultrasound (Pocus) Training As Part Of The Curriculum For Family Medicine Residents: An Approach To Incorporate Pocus In Primary Care, Nikita Sijapati, Byron Markel, Evan Stone, Edgar Mercado

West Florida Division GME Research Day 2023

No abstract provided.

Midgut Volvulus A Rare Cause Of Acute Abdomen In The Adult Patient, Mason S. Deinema, Saptarshi Biswas

South Atlantic Division GME Research Day 2023

No abstract provided.

Post-Procedural Vertebroplasty/Kyphoplasty Outcomes Of Patients From 2010-2020, Issac Ichoa, Waseem Wahood, Shyam Kurian, Mohamad Bydon, Jonathan Morris, David F. Kallmes, Waleed Brinjikji

East Florida Division GME Research Day 2023

Introduction: Vertebroplasty/kyphoplasty are common procedures used to treat vertebral compression fractures. The most common precipitating factor is osteoporosis, although there are other causes such as trauma, spinal tumors, etc. These procedures utilize fluoroscopy by inserting a trocar into the pathological vertebra. Once the trocar is in place, bone cement is then inserted into the vertebra in a vertebroplasty to help stabilize the fracture. In a kyphoplasty, a balloon is inserted after the trocar and is slowly inflated to correct the collapsed vertebra before injecting the cement. These procedures are commonly performed in an outpatient setting and generally yield good outcomes …

Documentation Burden: The Impact Of Inadequate Operative Reports On Surgrical Outcomes, Natalia Cavagnaro, Ali Siddiqui, Rainna Coelho, Nicole B. Lyons, Said Maldonado

Gulf Coast Division GME Research Day 2023

No abstract provided.

It’S A Mesh In These Bowels: Delayed Case Of Decade Long Mesh Eroding Into A Small Bowel Causing Obstruction And Intraperitoneal Sepsis, Margaret Rose, Jamie Pham, Adina Mcnair, Saptarshi Biswas

South Atlantic Division GME Research Day 2023

No abstract provided.

Are We “Pushing” Our Patients Toward Addiction? A Preliminary Post-Cesarean Survey To Quantify Narcotic Requirements For Pain Control, Aliya Nurani, Mikalah Maury, Merritt Mcgowan, Stephanie Tootle, Anthony Royek, Eric Shaw

South Atlantic Division GME Research Day 2023

No abstract provided.

Reducing Unnecessary Cbcs On The Inpatient Resident Service: Interviewing Stakeholders To Identify Underlying Causes, Feras Al-Moussally, Zara Bashir, Jorge Rodriguez, Ashlee Sidhu, Brain Murr, Liliana Franco, Jorge Restrepo, Ashwini Komarla

North Florida Division GME Research Day 2023

No abstract provided.

Confirming Diagnosis Of Copd With Spirometry, Stephan Zehring, Manal El-Hag, Gino Singer, David Nguyen, Eslam Mohamed, Michael Usbergi

North Florida Division GME Research Day 2023

No abstract provided.

Operative Management Of Grade V Liver Injury After Blunt Trauma: A Case Report, Laura Mena Albors, Garret Perry, Samantha Reiss, Darwin Ang

North Florida Division GME Research Day 2023

No abstract provided.