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Pharmacology, Toxicology and Environmental Health Commons™

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7,014 full-text articles. Page 256 of 266.

Comparative Study Of Anti-Oxidant Activity Of Leaf Extracts From Three Varieties Pomegranate, Pattra Ahmadi Pirshahid., Sarunya Laovitthayanggoon, Yaowaluk Khamphan, Phatsuda Chueboonmee, Chuleratana Banchonglikitkul 2012 Chulalongkorn University

Comparative Study Of Anti-Oxidant Activity Of Leaf Extracts From Three Varieties Pomegranate, Pattra Ahmadi Pirshahid., Sarunya Laovitthayanggoon, Yaowaluk Khamphan, Phatsuda Chueboonmee, Chuleratana Banchonglikitkul

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Effect Of Gamma-Irradiation On The Production Of Artemisinin In Artemisia Annua, Chawanop Kananukool, Thonghchai Koobkokkruad, Chalermpol Kirdmanee, Wanchai De-Eknamkul 2012 Chulalongkorn University

Effect Of Gamma-Irradiation On The Production Of Artemisinin In Artemisia Annua, Chawanop Kananukool, Thonghchai Koobkokkruad, Chalermpol Kirdmanee, Wanchai De-Eknamkul

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Gallic Acid And Derivatives As Acetylcholinesterase Inhibitors, Suttinee Santa-arthampreecha, Suwita Samakthanasan, Worawan Kitphati, Jaturong Pratuangdejkul, Veena Nukoolkam 2012 Chulalongkorn University

Gallic Acid And Derivatives As Acetylcholinesterase Inhibitors, Suttinee Santa-Arthampreecha, Suwita Samakthanasan, Worawan Kitphati, Jaturong Pratuangdejkul, Veena Nukoolkam

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Evaluation On Anti-Oxidant, Anti-Mutagenic And Cytotoxic Properties Of Active Fractions Of Thai “Long-Kong” (Lansium Domesticum Corr.) Fruits, Prapaipat Klungsupya, Nava Suthepakul, Sarunya Laovitthayanggoon, Jeerayu Thongdon-A, Srisak Trangwacharakul, Srichan Phomchirasilp 2012 Chulalongkorn University

Evaluation On Anti-Oxidant, Anti-Mutagenic And Cytotoxic Properties Of Active Fractions Of Thai “Long-Kong” (Lansium Domesticum Corr.) Fruits, Prapaipat Klungsupya, Nava Suthepakul, Sarunya Laovitthayanggoon, Jeerayu Thongdon-A, Srisak Trangwacharakul, Srichan Phomchirasilp

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Anti-Oxidative Effects Against Tight Junction Barrier Disruption Of Proteins Isouated From Cajanus Cajan, Muangman T., Klungsupya P, Leelamanit W, Watari A, Yagi K 2012 Chulalongkorn University

Anti-Oxidative Effects Against Tight Junction Barrier Disruption Of Proteins Isouated From Cajanus Cajan, Muangman T., Klungsupya P, Leelamanit W, Watari A, Yagi K

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Development Of Solid Lipid Nanoparticles Containing Astaxanthin From Shrimp Shell Extract, Kritsada Roopvai, Parkpoom Tengamnuay, Prapasri Sinswat 2012 Chulalongkorn University

Development Of Solid Lipid Nanoparticles Containing Astaxanthin From Shrimp Shell Extract, Kritsada Roopvai, Parkpoom Tengamnuay, Prapasri Sinswat

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Fabrication And Evaluation Of Cationic Exchange Polystyrene Nanofibers For Oral Drug Delivery, Todsapon Nitanan, Prasert Akkaramongkolpom, Tanasait Ngawhirunpat, Theerasak Rojanarata, Praneet Opanasopit 2012 Chulalongkorn University

Fabrication And Evaluation Of Cationic Exchange Polystyrene Nanofibers For Oral Drug Delivery, Todsapon Nitanan, Prasert Akkaramongkolpom, Tanasait Ngawhirunpat, Theerasak Rojanarata, Praneet Opanasopit

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Effects Of Dry Binders On The Mechanical And Disintegration Properties Of Nava-Kote Tablets, Chaivut Lorpongpaiboon, Thitianan Kulsirirat, Kanagam Hammaworachat, Siracha Kasemsuwan, Sunee Channarong 2012 Chulalongkorn University

Effects Of Dry Binders On The Mechanical And Disintegration Properties Of Nava-Kote Tablets, Chaivut Lorpongpaiboon, Thitianan Kulsirirat, Kanagam Hammaworachat, Siracha Kasemsuwan, Sunee Channarong

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Development Of Dietary Supplement Tablets Containing The Extract Of Mangosteen Fruit Rind, Methanee Khoprasert, Pennapa Srichaiyon, Cholthicha Insom, Wiriyapom Sirikul, Werayut Pothitirat, Wandee Gritsanapan, Orawan Chitvanich 2012 Chulalongkorn University

Development Of Dietary Supplement Tablets Containing The Extract Of Mangosteen Fruit Rind, Methanee Khoprasert, Pennapa Srichaiyon, Cholthicha Insom, Wiriyapom Sirikul, Werayut Pothitirat, Wandee Gritsanapan, Orawan Chitvanich

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Formulation Development Of Multilayer Sustained Release Tablets Of Sodium Valproate Combined With Valproic Acid, Worawan Saingam, Poj Kulvanich 2012 Chulalongkorn University

Formulation Development Of Multilayer Sustained Release Tablets Of Sodium Valproate Combined With Valproic Acid, Worawan Saingam, Poj Kulvanich

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Quantitative Analysis Of “Tee Ka Tuk” Formulation Using Tlc-Densitometric Method, Maneekran Napakraw, Thitima Lhinhatrakool, Prasan Tanguenyongwatana 2012 Chulalongkorn University

Quantitative Analysis Of “Tee Ka Tuk” Formulation Using Tlc-Densitometric Method, Maneekran Napakraw, Thitima Lhinhatrakool, Prasan Tanguenyongwatana

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Author Index, n/a 2012 Chulalongkorn University

Author Index, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.


Floating And Mucoadhesive System Of Furosemide: Development And In Vitro Evaluation, Krunal Takarkhede, Dilesh Jagdish, Shagufta Khan, Pramod Yeole 2012 Chulalongkorn University

Floating And Mucoadhesive System Of Furosemide: Development And In Vitro Evaluation, Krunal Takarkhede, Dilesh Jagdish, Shagufta Khan, Pramod Yeole

The Thai Journal of Pharmaceutical Sciences

Furosemide is poorly soluble in acidic pH and absorbed from the upper part of the Gl tract. We, therefore, aimed to develop a sustained release gastroretentive beads containing furosemide inclusion complex. The different formulations of floating beads we...


Influence Of Ephx1 Polymorphism And Clinical Factors On Carbamazepine Resistant Epilepsy, Khanistha Tuanthaisong, Yotin Chinvarun, Mayuree H. Tantisira, Pornpimol Kijsanayotin 2012 Chulalongkorn University

Influence Of Ephx1 Polymorphism And Clinical Factors On Carbamazepine Resistant Epilepsy, Khanistha Tuanthaisong, Yotin Chinvarun, Mayuree H. Tantisira, Pornpimol Kijsanayotin

The Thai Journal of Pharmaceutical Sciences

The treatment outcomes of carbamazepine (CBZ) vary widely among patients. Single nucleotide polymorphisms (SNPs) in genes involved in pharmacokinetics and pharmacodynamics of CBZ may influence patients’ response to CBZ. We aimed to investigate the asso...


Simultaneous Spectrophotometric Determination Of Difloxacin And Enrofloxacin In Urine Samples By Partial Least Squares Regression (Pls) And Direct Orthogonal Signal Correction-Partial Least Squares Regression (Disc-Ols) Methods, Kuldeep Kaur, Ashok Kumar Malik, Baldev Singh, M. Godarzi 2012 Chulalongkorn University

Simultaneous Spectrophotometric Determination Of Difloxacin And Enrofloxacin In Urine Samples By Partial Least Squares Regression (Pls) And Direct Orthogonal Signal Correction-Partial Least Squares Regression (Disc-Ols) Methods, Kuldeep Kaur, Ashok Kumar Malik, Baldev Singh, M. Godarzi

The Thai Journal of Pharmaceutical Sciences

Simultaneous determination of difloxacin and enrofloxacin using two chemometric methods, partial least squares regression (PLS) and direct orthogonal signal correction-partial least squares regression (DOSC-PLS) is described in this paper. The simultaneous determination of these drugs is difficult due to spectral interferences. The calibration graphs were linear in the range of 1-10 μg mL-1 and 1-9 μg mL-1 with detection limits of 0.52 and 0.15 μg mL-1 for difloxacin and enrofloxacin, respectively. The experimental calibration matrix was designed with 25 mixtures of these drugs. The PLS and DOSC-PLS were used for multivariate calibration of spectrophotometric data. The root mean square error …


Facile Derivative Uv Spectroscopy Method: Simultaneous Estimation Of Tinidazole And Fluconazole In Combined Tablet Dosage Form, Saurabh Pandey, Preeti Pandey, Shaifali Dubey, Udisha Chaturvedi, Awani K. Rai 2012 Chulalongkorn University

Facile Derivative Uv Spectroscopy Method: Simultaneous Estimation Of Tinidazole And Fluconazole In Combined Tablet Dosage Form, Saurabh Pandey, Preeti Pandey, Shaifali Dubey, Udisha Chaturvedi, Awani K. Rai

The Thai Journal of Pharmaceutical Sciences

Two derivative spectrophotometric methods have been developed for simultaneous determination of tinidazole and fluconazole in pharmaceutical formulations. The first method depends on utilization of first derivative UV spectrophotometry, with zero-crossing and peak-to-base measurement at 260.57 & 264.23 nm for fluconazole and 263.86 & 318.85 nm for tinidazole. The second method, compensation technique depends on first derivative of the ratio-spectra by measurements of the amplitudes for tinidazole and fluconazole. Calibration graphs were established for tinidazole and fluconazole in the range of 10-100 μg ml-1 and 2-20 μg ml-1, respectively. All proposed methods have been extensively validated. The results were found to …


Simultaneous Estimation Of Cefixime And Cloxacillin In Human Plasma By Reversed Phase-Hplc With Uv Detection, Sommath D. Bhinge, Sharangouda M. Malipatil, Lalit V. Sonawane 2012 Chulalongkorn University

Simultaneous Estimation Of Cefixime And Cloxacillin In Human Plasma By Reversed Phase-Hplc With Uv Detection, Sommath D. Bhinge, Sharangouda M. Malipatil, Lalit V. Sonawane

The Thai Journal of Pharmaceutical Sciences

An accurate, rapid and simple reversed-phase high performance liquid chromatography (RP-HPLC) method was developed and validated for simultaneous estimation of cefixime, cloxacillin and for chloramphenicol (internal standard) in human plasma. Chromatographic separation was accomplished using CAPCELL PAK C8 (4.6 mm Ó 250 mm, 5 μm) analytical column using phosphate buffer, methanol and acetonitrile (40:45:15) as eluent. Detection and quantification were performed by UV/Vis detection at 225 nm. The lower limit of detection and quantification were 0.01 μg†mL-1 and 0.25 μg†mL-1 for cefixime, 0.03 μg†mL-1 and 0.39 μg†mL-1 for cloxacillin. The calibration curves were linear over the concentration range 0.5 to …


Thrombolytic Activity Of Some Spices And Plants Available In Bangladesh, Md. Rakib AI-Manun, Nabiha Amrin, Jahura Begum, Md. Abdul Mazid 2012 Chulalongkorn University

Thrombolytic Activity Of Some Spices And Plants Available In Bangladesh, Md. Rakib Ai-Manun, Nabiha Amrin, Jahura Begum, Md. Abdul Mazid

The Thai Journal of Pharmaceutical Sciences

Thrombolytic activities of some plants, namely Tamarindus indica (Fabaceae), Flemingia congesta (Fabaceae), Lawsonia inermis (Lythraceae), Mesua nagassarium (Clusiaceae, and spices, namely Coriandrum sativum (Apiaceae), Curcuma longa (Zingiberaceae), Cinnamomum tamala (Lauraceae), Nigella sativa (Ranunculaceae), Eugenia aromaticum (Myrtaceae), available in Bangladesh, were evaluated using an in vitro model. The thrombolytic activity in terms of percentage of weight loss of in vitro formed clots were found as C. sativum 43.25 ± 7.18%, C. longa 53.32 ± 4.96%, C. tamala 22.10 ± 3.18%, N. sativa 28.49 ± 3.72%, E. aromaticum 32.18 ± 3.10%, T. indica 28.91 ± 2.29%, F. congesta 35.27 ± 7.35%, L. …


Lactobacillus Plantarum T23/3 As A Potential Probiotic Strain Isolated From Faces, Titpawan Nakpheng, Rosainee Kha, Neelam Balekar, Sanae Kaewnopparat, Teerapol Srichana 2012 Chulalongkorn University

Lactobacillus Plantarum T23/3 As A Potential Probiotic Strain Isolated From Faces, Titpawan Nakpheng, Rosainee Kha, Neelam Balekar, Sanae Kaewnopparat, Teerapol Srichana

The Thai Journal of Pharmaceutical Sciences

The present study was undertaken to evaluate the properties of Lactobacillus plantarum T23/3 isolated from the feces of healthy elderly volunteer. The L. plantarum T23/3 showed better tolerance property to bile acid, simulated gastric fluid (SGF) and simulated intestinal fluid (SIF), and exhibited antimicrobial activity against tested enteropathogens. It formed macroscopic granules with surface hydrophobicity and co-aggregated with tested microbial strain. It was resistant to some antibiotics used for treatment of diarrhea so there is possibility to co-administer L. plantarum as probiotic with antidiarrheal therapy. Furthermore, adhesion and significant potential for decreasing adhesion of pathogens (E. coli 2601 and V. …


Application Of A Stability-Indicating Hptlc Method For Simultaneous Determination Of Chloramphenicol And Dexamethasone Sodium Phosphate In Eye Drop, Yimer Seid, Araya Hymete, Adnan A. Bekhit 2012 Chulalongkorn University

Application Of A Stability-Indicating Hptlc Method For Simultaneous Determination Of Chloramphenicol And Dexamethasone Sodium Phosphate In Eye Drop, Yimer Seid, Araya Hymete, Adnan A. Bekhit

The Thai Journal of Pharmaceutical Sciences

A high performance thin layer chromatography (HPTLC) method was developed and validated for the simultaneous quantification of dexamethasone sodium phosphate and chloramphenicol in eye drop. The HPTLC separation was achieved on an aluminum-backed layer of silica gel 60F254 using acetonitrile: water: ammonia (10:3:0.5 v/v/v), pH adjusted to 7.8 with 1M HCl, as a mobile phase. The densitometric determination of dexamethasone phosphate and chloramphenicol was carried out at 262 nm. Calibration curves for dexamethasone phosphate and chloramphenicol were linear in the range of 80-300 ng and 400-1400 ng, respectively. The method was validated according to International Conference on Harmonization (ICH) guidelines …


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