Farnesol-Mediated Regulation Of Hepatic Lipid Metabolism In Heparg Cells,
2016
Wayne State University
Farnesol-Mediated Regulation Of Hepatic Lipid Metabolism In Heparg Cells, Asmita Pant
Wayne State University Dissertations
Non-alcoholic fatty liver disease is emerging as one of the most common liver disorders worldwide and is characterized by accumulation of triglycerides (TGs) in liver. The endogenous isoprenoid farnesol reduces hepatic TG levels in rodents, and this effect appears to involve at least two nuclear receptors, peroxisome proliferator-activated receptor α and farnesoid X receptor (FXR). However, farnesol’s effects on human hepatic lipid metabolism are currently unknown. The objective of this study is to evaluate how farnesol treatment would affect hepatic lipid accumulation and metabolism in a cellular model of human hepatic steatosis that was created by incubating the hepatocyte-like HepaRG …
An Ecotoxicological Survey Of Tributaries Of The Selenge River,
Mongolia, August 2010,
2016
Russian Academy of Sciences
An Ecotoxicological Survey Of Tributaries Of The Selenge River, Mongolia, August 2010, Viktor T. Komov, Ch. Javzan, William G. Brumbaugh
Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298
The biodiversity of the Selenga river basin and the receiving waters of the lake Baikal, are among the greatest in the world with over 1,700 known endemic species of plants and animals. Mining activities along the Selenga river and its tributaries pose a major threat of chemical contamination, potentially reducing habitat quality and suitability for aquatic species. Moreover, the Selenga river serves as a major water source for the lake Baikal. Little information exists on the chemical contaminant concentrations in the Selenga river basin. Thus, the objectives of our study were to evaluate the concentrations of metals in soil, sediment, …
Citrate Coated Silver Nanoparticles With Modulatory Effects On Aflatoxin Biosynthesis In Aspergillus Parasiticus,
2016
University of South Carolina
Citrate Coated Silver Nanoparticles With Modulatory Effects On Aflatoxin Biosynthesis In Aspergillus Parasiticus, Chandrani Mitra
Theses and Dissertations
The manufacture and usage of silver nanoparticles has drastically increased in recent years (Fabrega et al. 2011a). Hence, the levels of nanoparticles released into the environment through various routes have measurably increased and therefore are concern to the environment and to public health (Panyala, Peña-Méndez and Havel 2008). Previous studies have shown that silver nanoparticles are toxic to various organisms such as bacteria (Kim et al. 2007), fungi (Kim et al. 2008), aquatic plants (He, DorantesAranda and Waite 2012a), arthropods (Khan et al. 2015), and mammalian cells (Asharani, Hande and Valiyaveettil 2009) etc. Most of the toxicity studies are carried …
Mucus Secretion Stimulation: A Mechanism In Gastroprotective Effect Of Zingiber Officinale,
2016
Chulalongkorn University
Mucus Secretion Stimulation: A Mechanism In Gastroprotective Effect Of Zingiber Officinale, Gaewbpragaan Chantharangsikul, Worawan Kitpati, Noppamas Soonthornchareonnon, Achariya Sailasuta, Arunporn Itharat, Wisuda Suvitayavat
The Thai Journal of Pharmaceutical Sciences
There are several studies on the gastroprotective effect of Z. officinale, however, the nature of this effect has not been fully elucidated. The present study investigated the gastroprotective activity and underlying mechanism of the 95% ethanolic extrac...
Validation Of An Rp-Hplc Method For Quantitative Analysis Of Phikud Navakot Extract Using The Standard Addition Method,
2016
Chulalongkorn University
Validation Of An Rp-Hplc Method For Quantitative Analysis Of Phikud Navakot Extract Using The Standard Addition Method, Pavena Kumnerdnon, Pornchai Rojsitthisak, Nuansri Niwattisaiwong, Uthai Sotanaphun, Jittima Chatchawalsaisin, Narueporn Sutanthavibul
The Thai Journal of Pharmaceutical Sciences
The aim of the study was to develop a reversed phase-high performance liquid chromatography (RP-HPLC) analytical method for monitoring three analytical markers, gallic acid, vanillic acid and ferulic acid, in Phikud Navakot extract (NVK-E), using the sta...
Comparison Of Sedimentation Stability Of Ampicillin Trihydrate Suspensions Using Near Infrared Extinction Profiles,
2016
Chulalongkorn University
Comparison Of Sedimentation Stability Of Ampicillin Trihydrate Suspensions Using Near Infrared Extinction Profiles, Padala Narasimha Murthy, Meduri Vimala Devi, Sudhir Kumar Sahoo, Anjan Kumar Mahapatra, Madhusmruti Khandai
The Thai Journal of Pharmaceutical Sciences
Suspensions are one of the most important and popular dosage forms. A large number of drugs are formulated in the form of suspensions and are available commercially. Stability studies of suspensions are very important to enable the patient to receive t...
Herbs Used As A Cure For Rheumatiod Arthritis: A Review,
2016
Chulalongkorn University
Herbs Used As A Cure For Rheumatiod Arthritis: A Review, Santhosh Aruna Mamidi
The Thai Journal of Pharmaceutical Sciences
Rheumatoid arthritis is chronic, progressive, disabling autoimmune disease characterized by systemic inflammation of joints, damaging cartilage and bone around the joints. It is a systemic disease which means that it can affect the whole body and interna...
Effects Of Continuous Exposure To Bisphenol A On Male And Female Mice From Prenatally To Adulthood,
2016
Chulalongkorn University
Effects Of Continuous Exposure To Bisphenol A On Male And Female Mice From Prenatally To Adulthood, Kannikar Chatsantiprapa, Tip-Arpa Sophon, Jintana Sattayasai
The Thai Journal of Pharmaceutical Sciences
BisphenolA (BPA), a monomer estrogenic chemical of many plastic products has controversial biological effects. This study assessed the effects at 0.05 mg/kg BW/day (Tolerable Daily Intake, TDI) and 0.5 mg/kg BW/day (10TDI), in male and female mice contin...
Outcomes Of Pharmaceutical Care Services In Promoting Rational Drug Use,
2016
Chulalongkorn University
Outcomes Of Pharmaceutical Care Services In Promoting Rational Drug Use, Wanna Sriviriyanupap, Roungtiva Muenpa
The Thai Journal of Pharmaceutical Sciences
Pharmacists provide pharmaceutical care service in order to support rational drug use. However, still lack of evidence to show its outcomes. Therefore, this cross-sectional descriptive study and qualitative study were conducted to evaluate the outcomes o...
Calotropis Procera: A Phytochemical And Pharmacological Review,
2016
Chulalongkorn University
Calotropis Procera: A Phytochemical And Pharmacological Review, Neelam Balekar
The Thai Journal of Pharmaceutical Sciences
Medicinal plants are used from the ancient time as the major sources of drugs.The fact is that we can obtain many of the presently available drugs, either directly in the extract form or in the modified synthetic form. Naturally, plants have ability to s...
Effect Of Fat Content On Characteristics Of Ice Cream Fortified With Calcium And Vitamin D3,
2016
Chulalongkorn University
Effect Of Fat Content On Characteristics Of Ice Cream Fortified With Calcium And Vitamin D3, Rossarin Tansawat
The Thai Journal of Pharmaceutical Sciences
Calcium and vitamin D play important roles in bone homeostasis. Several studies reported inadequate intakes of these two nutrients in many population groups. Food fortification is one way to solve the problem. The objective of this study was to develop...
Exploring Knowledge Acquisition Technique For New Start-Up Community Food Enterprises,
2016
Chulalongkorn University
Exploring Knowledge Acquisition Technique For New Start-Up Community Food Enterprises, Wattanapong Luechoowong, Ruangthip Tantipidoke, Rungpetch Sakulbumrungsil
The Thai Journal of Pharmaceutical Sciences
Objective: This qualitative study is conducted to explore the knowledge acquisition techniques from five successful food enterprises at the new entry of community business. Methods: Five successful community food producers were purposively selected unde...
Stilbenoids From The Stem Of Diospyros Collinsae, The First Evidence For The Production Of Stilbene Derivatives In Ebenaceous Plants,
2016
Chulalongkorn University
Stilbenoids From The Stem Of Diospyros Collinsae, The First Evidence For The Production Of Stilbene Derivatives In Ebenaceous Plants, Buntita Bumroong, Witchuda Thanakijcharoenpath
The Thai Journal of Pharmaceutical Sciences
Two stilbenoids, diptoindonesin D (1) and diptoindonesin G (2), were isolated from the stem of Diospyros collinsae Craib (Ebenaceae), together with four triterpenoids, namely friedelin, lupeol, betulin and betulinic acid. Their structures were determined...
Exploring Key Factors Affecting The Competitiveness Of Thailand’S Cosmetic Industry,
2016
Chulalongkorn University
Exploring Key Factors Affecting The Competitiveness Of Thailand’S Cosmetic Industry, Neeranard Jinachai, Win Winit-Watjana, Puree Anantachoti
The Thai Journal of Pharmaceutical Sciences
The Thai cosmetic industry has continuously grown, but relevant factors impacting on the industry remained un-assessed. This study was intended to explore key factors affecting the country competitiveness. The Diamond model was adapted as the conceptual ...
Anaphylactic Shock Caused By A Selective Allergy To Ceftriaxone: A Case Report,
2016
Chulalongkorn University
Anaphylactic Shock Caused By A Selective Allergy To Ceftriaxone: A Case Report, Wichai Santimaleeworagun
The Thai Journal of Pharmaceutical Sciences
Ceftriaxone has been wildly used due to once daily dosing. However, case with anaphylaxis secondary to ceftriaxone has been documented and the other β-lactam might be caution. We reported an 89 year-old patient who had history of type I hypersensitivity...
Comparative Evaluation Of Neuroprotective Effect Of Three Varieties Of Allium Cepa In Chronic Constriction Injury Induced Neuropathic Pain,
2016
Chulalongkorn University
Comparative Evaluation Of Neuroprotective Effect Of Three Varieties Of Allium Cepa In Chronic Constriction Injury Induced Neuropathic Pain, Amit Kumar, Kundan Singh Bora, Amteshwar Singh Jaggi, Richa Shri
The Thai Journal of Pharmaceutical Sciences
Objectives: Allium cepa has been used extensively for culinary purposes as well as in traditional system of medicine. A number of varieties of A. cepa are available commercially with varietal differences in phytoconstituents and biological activities. Ho...
Effect Of Time-Dependent Polymer On The Dissolution Rate Of Flurbiprofen: Formulation And Evaluation Of Colon-Specific Matrix Tablets,
2016
Chulalongkorn University
Effect Of Time-Dependent Polymer On The Dissolution Rate Of Flurbiprofen: Formulation And Evaluation Of Colon-Specific Matrix Tablets, Sateesh Kumar Vemula, Selamu Kebamo, Balisa Mosisa, Biniam Paulos
The Thai Journal of Pharmaceutical Sciences
An effort was made in the present study to prepare flurbiprofen matrix tablets to improve the therapeutic efficacy by increasing therapeutic drug concentrations in lower intestine i.e., site-specific release to colon. The current experiment was aimed to ...
Qsar Study On Quinolinecarbaldehyde Derivatives As Potential Anti-Tubercular Agents,
2016
Chulalongkorn University
Qsar Study On Quinolinecarbaldehyde Derivatives As Potential Anti-Tubercular Agents, Ravichandran Veerasamy, Shalini Sivadasan, Venakteskumar Krishnamoorthi, Harish Rajak, Sureshkumar Krishnan
The Thai Journal of Pharmaceutical Sciences
This study investigated the quantitative structure–activity relationships (QSAR) for a range of substituted quinolinecarbaldehyde derivatives as anti-tubercular agent by multiple linear regression analysis. The derived QSAR models have been statistical...
Synthesis And Evaluation Of Pi3kγ Enzyme Inhibitory Activity Of Novel (1h-Pyrazol-4-Yl)Methanamine,
2016
Chulalongkorn University
Synthesis And Evaluation Of Pi3kγ Enzyme Inhibitory Activity Of Novel (1h-Pyrazol-4-Yl)Methanamine, Sukumar Bepary, In Kwon Youn, Hee-Jong Lim, Ge Hyeong Lee
The Thai Journal of Pharmaceutical Sciences
A series of (1H-pyrazol-4-yl)methanamines have been synthesized and then were evaluated for the PI3Kγ enzyme inhibitory potential. Minor modification of the initially synthesized molecules offered significant improvement of the inhibitory potential from...
Cross Immediate Hypersensitivity Between Ciprofloxacin And Levofloxacin: A Case Report And Literature Review,
2016
Chulalongkorn University
Cross Immediate Hypersensitivity Between Ciprofloxacin And Levofloxacin: A Case Report And Literature Review, Chotirat Nakaranurack
The Thai Journal of Pharmaceutical Sciences
Fluoroquinolones can show cross-reactivity because of the similar chemical structure. Levofloxacin is a new fluoroquinolone and can be a safe alternative due to low cross-reactivity. This is a case report showing cross-reactivity between ciprofloxacin an...
