Nutrition Commons^™

Leptin Receptor Neurons In The Dorsomedial Hypothalamus Require Distinct Neuronal Subsets For Thermogenesis And Weight Loss, Marie Francois, Laura Kaiser, Yanlin He, Yong Xu, J Michael Salbaum, Sangho Yu, Christopher D Morrison, Hans-Rudolf Berthoud, Heike Münzberg

Children’s Nutrition Research Center Staff Publications

The dorsomedial hypothalamus (DMH) receives inputs from the preoptic area (POA), where ambient temperature mediates physiological adaptations of energy expenditure and food intake. Warm-activated POA neurons suppress energy expenditure via brown adipose tissue (BAT) projecting neurons in the dorsomedial hypothalamus/dorsal hypothalamic area (dDMH/DHA). Our earlier work identified leptin receptor (Lepr)-expressing, BAT-projecting dDMH/DHA neurons that mediate metabolic leptin effects. Yet, the neurotransmitter (glutamate or GABA) used by dDMH/DHALepr neurons remains unexplored and was investigated in this study using mice. We report that dDMH/DHALepr neurons represent equally glutamatergic and GABAergic neurons. Surprisingly, chemogenetic activation of glutamatergic and/or GABAergic dDMH/DHA neurons were capable …

An Evaluation Of Sports Nutrition Knowledge And Influencing Factors In Ncaa Division Iii Athletes, Kerrie Berends, Michael J. Wierenga, Madeline Frens

University Faculty Publications and Creative Works

Introduction:This study evaluated the sports nutrition knowledge of NCAA Division III (DIII) athletes, examining the influence of demographic and sport-specific factors. Nutrition is a critical component of athletic performance, recovery, and overall health, yet prior research indicatescollegiate athletes often lack adequate nutrition knowledge.

Methods: A total of 412 athletes, representing 17 different sports across endurance, power, and skill categories, completed the validated Abridged Nutrition for Sport Knowledge Questionnaire (A-NSKQ). The sample included freshmen through fifth-year seniorathletes, predominantlyCaucasian (85%).

Results: The average A-NSKQ score was 17.1 out of 35 (48.9%), indicating suboptimal knowledge. Significant differences were found across …

Research Progress And Clinical Translation Potential Of Coronary Atherosclerosis Diagnostic Markers From A Genomic Perspective, Hanxiang Liu, Yuchen Zhang, Yueyan Zhao, Yuzhen Li, Xiaofeng Zhang, Lingyu Bao, Rongkai Yan, Yixin Yang, Huixian Zhou, Jinming Zhang, Siyuan Song

Children’s Nutrition Research Center Staff Publications

Objective: Coronary atherosclerosis (CAD) is characterized by arterial intima lipid deposition, chronic inflammation, and fibrous tissue proliferation, leading to arterial wall thickening and lumen narrowing. As the primary cause of coronary heart disease and acute coronary syndrome, CAD significantly impacts global health. Recent genetic studies have demonstrated CAD's polygenic and multifactorial nature, providing molecular insights for early diagnosis and risk assessment. This review analyzes recent advances in CAD-related genetic markers and evaluates their diagnostic potential, focusing on their applications in diagnosis and risk stratification within precision medicine.

Methods: We conducted a systematic review of CAD genomic studies from PubMed and …

A Β-Hydroxybutyrate Shunt Pathway Generates Anti-Obesity Ketone Metabolites, Maria Dolores Moya-Garzon, Mengjie Wang, Veronica L Li, Xuchao Lyu, Wei Wei, Alan Sheng-Hwa Tung, Steffen H Raun, Meng Zhao, Laetitia Coassolo, Hashim Islam, Barbara Oliveira, Yuqin Dai, Jan Spaas, Antonio Delgado-Gonzalez, Kenyi Donoso, Aurora Alvarez-Buylla, Francisco Franco-Montalban, Anudari Letian, Catherine P Ward, Lichao Liu, Katrin J Svensson, Emily L Goldberg, Christopher D Gardner, Jonathan P Little, Steven M Banik, Yong Xu, Jonathan Z Long

Children’s Nutrition Research Center Staff Publications

β-Hydroxybutyrate (BHB) is an abundant ketone body. To date, all known pathways of BHB metabolism involve the interconversion of BHB and primary energy intermediates. Here, we identify a previously undescribed BHB secondary metabolic pathway via CNDP2-dependent enzymatic conjugation of BHB and free amino acids. This BHB shunt pathway generates a family of anti-obesity ketone metabolites, the BHB-amino acids. Genetic ablation of CNDP2 in mice eliminates tissue amino acid BHB-ylation activity and reduces BHB-amino acid levels. The most abundant BHB-amino acid, BHB-Phe, is a ketosis-inducible congener of Lac-Phe that activates hypothalamic and brainstem neurons and suppresses feeding. Conversely, CNDP2-KO mice exhibit …

Theory-Based Nutrition Education To Improve Food Security In Postsecondary Students, Tara Kelly

All ETDs from UAB

The high prevalence of food insecurity among college students is a public health concern that requires well designed interventions to address. College students experiencing food insecurity are more likely to practice diet-related behaviors that contribute to poor health, yet this population lacks the necessary knowledge and skills to make adequate behavior changes. The purpose of this present dissertation is to (1) assess preliminary data collected to inform the development of a theory-based nutrition education intervention; then (2) evaluate the feasibility of this novel intervention design and (3) its effectiveness at improving college students’ food security and factors that may impact …

Exploring Nutritional Needs In Spinal Cord Injury: Dietitian Perspectives, Bowel Health, And Dietary Recommendations, Ayse Gul Zengul

All ETDs from UAB

Spinal cord injury (SCI) is a global condition affecting millions of people and leading to life-altering health complications. It profoundly alters body composition and metabolic rate, which need to be addressed with SCI-specific nutritional strategies. Muscle atrophy, fat accumulation, and decreased energy expenditure often lead to secondary health complications such as chronic diseases and SCI-related health problems, including pressure injuries and bowel dysfunction. Although nutrition plays a critical role in SCI management, our understanding of specific dietary needs for this population remains incomplete. This dissertation aims to comprehensively investigate the nutritional challenges and needs of individuals with SCI, ultimately developing …

Evaluating The Contributions Of Nutrition Knowledge And Food Skills As Predictors Of Dietary Behavior, Diet Competence, And Diet Autonomy In Pre-Hypertensive Rural And Micropolitan Dwelling African American Adults In Alabama, Mary Catherine Robertson Lawson

All ETDs from UAB

Introduction: African American (AA) adults living in rural, Southeastern communities experience disproportionately high rates of obesity-related chronic diseases. Many factors contributing to this health disparity are related to negative Social Determinants of Health that have individual and community level impacts. Nutrition knowledge (NK) and food skills (FS) are forms of health literacy that have been understudied in rural-dwelling AA adults. Understanding their relationships with self-perceived diet competence, autonomy, motivations, as well as diet behaviors and health outcomes could inform the development of future health research and policy. Methods: A scoping review was conducted to identify key trends and information gaps …

Effects Of Whole-Food, Plant-Centered Diets On Glycemic Control, Medication Use, Ectopic Fat, And Cardiovascular Health In Adults With Type 2 Diabetes, Cody Hanick

All ETDs from UAB

Type 2 diabetes (T2D) is a global health and economic concern. Safe and effective treatments for T2D, including dietary approaches, are limited. Additionally, it remains unclear whether dietary carbohydrate quality or quantity matters more for managing T2D. Most nutrient-dense carbohydrate quality sources—such as fruit, vegetables, legumes, and whole grains—come from plant foods and are recommended for people with T2D by the American Diabetes Association. Furthermore, when these food groups are combined into a dietary pattern, a whole-food, plant-based (WFPB) diet is created. However, few studies have tested the effects of a WFPB diet or carbohydrate-rich food groups in people with …

Dietary Program For The Reduction Of Type 2 Diabetes Prevalence In A South Texas Border Region, Siddiqua Noor

Doctor of Nursing Practice Final Project Abstract

PURPOSE The purpose of this project was to create a culturally sensitive dietary program template to serve as a guide to offer healthier food alternatives to reduce the incidence of type 2 diabetes while not compromising on their Hispanic heritage.

BACKGROUND This project was implemented in a South Texas border community which has nearly twice the national average of Type 2 Diabetes Mellitus, which presents a significant public health challenge.

METHODOLOGY The project followed the Plan-Do-Study-Act cycle and incorporated the Health Belief Model. A dietary pamphlet featuring local culturally relevant food options was developed. The material was presented at two …

Evaluating A Pilot Nutrition Education Curriculum For Autistic Young Adults: Rev It Up! For Asd, Samantha Schaap

Health and Nutritional Sciences Graduate Students Plan B Capstone Projects

Objective: People with autism spectrum disorder (ASD) have poor diet and exercise behaviors, which lead to higher prevalences of overweight/obesity and diet-related diseases. Young adults with ASD are particularly understudied regarding nutrition educational approaches; thus, our study aimed to examine the impact of Rev It Up! for ASD, an adapted Extension nutrition and physical activity curriculum adapted for this population.
Methods: The Rev It Up! curriculum was reviewed by four experts in autistic education to identify adaptations needed for the Rev It Up! for ASD pilot. The intervention was conducted in 10, 90-minute sessions from February-April 2025, where students participated …

Diabetes, Edwin Espinosa Vazquez

CSU Tower Day

1.2 million Americans are affected with diabetes each year.

○ Increase in hospitalizations, emergency room visits

● Diabetes has a higher rate of prevalence among the middle aged, older aged and non- Americans in the US.

● Diabetes presents a high risk of Cardiovascular Disease, Kidney failure, blindness, etc.

● Exercise, dietary changes, and medication can prevent or delay from the onset of type 2 diabetes (T2D).

Perspectives On Using Fats And Oils In Poultry Production, Brian J. Kerr

Proceedings of the Arkansas Nutrition Conference

These proceedings describe lipid composition of fats and oils and outline fatty acid quality measurements. In addition, fat and oil energy composition and digestibility are presented. Finally, these proceedings describe ways to enhance lipid digestibility with emulsifiers and preventing lipid peroxidation with antioxidants.

Sustainable And Profitable Broiler Nutrition, Sergio R. Fernandez

Proceedings of the Arkansas Nutrition Conference

These proceedings accompany a presentation on optimizing protein nutrition of broilers while minimizing environmental impacts of nitrogen excretion. The continual advancement of muscle development in modern broilers requires constant alignment of amino acid needs. These proceedings outline the importance and progression of feed grade amino acid supplementation in broiler nutrition.

Net Energy: The Precision Path To Sustainability, P. Srichana, A. C. Tay-Zar, M. Wongphatcharachai, C. Chanseyha

Proceedings of the Arkansas Nutrition Conference

Adaptation of the net energy system in broiler diets will increase least cost formulation flexibility. These proceedings outline a net energy system developed and implemented in practice. In addition to lower carbon and nitrogen inputs in dietary formulation, the net energy system reduced feed costs.

Layer Industry Update: Nutrition Associated With Changes In Production Systems, Kenneth E. Anderson, Ishab Poudel

Proceedings of the Arkansas Nutrition Conference

This is not a hardcore research presentation but rather an overview of three North Carolina Layer Performance and Management Tests. I used the 39th, 40th, and 41st Layer Test Reports that cover the years 2013 through 2025. The proceedings cover white and brown egg strains as groups and the cage and cage-free production environments. Over all three of these tests the production environments were the same and met UEP Cage standards and the Humane Farm Animal Care cage-free standards. There are papers outlining the changes in more detail with all the statistics. This is an overview of visual trends in …

Field Experience And Production Challenges In Australia And New Zealand, Nick Rodgers

Proceedings of the Arkansas Nutrition Conference

Variability management represents the primary technical challenge facing the Australian and New Zealand (ANZ) broiler industry's vertically integrated operations. This analysis examines systematic approaches to controlling seasonal performance fluctuations, raw material quality variations, emerging disease pressures, and evolving welfare demands. Key variability sources include climatic extremes, season to season raw material quality and nutrient value variability and intermittent [mostly enteric] disease challenges, particularly in no antibiotics ever (NAE) production systems. Solutions require a scientific, data-driven approach with insights from field experience for causation identification and a collaborative approach within business functional units, and across industry collaborators such as suppliers and …

Nutrition Security – Why It Matters?, Priscilla Ayine, Veronica Oates

Extension Publications

No abstract provided.

Science, Physiology, And Nutrition For The Nonscientist, Judi S. Morrill

Open Educational Resources

A wonderful blend of physiology, nutrition, biochemistry, genetics, biology, evolution, chemistry--what we all need to know as informed citizens. A basic knowledge of the life sciences and how our bodies work--to promote our own good health, especially as we're bombarded with misleading advertisements, soundbites, and the like. DNA fingerprinting, calorie requirements, dietary advice, genetic engineering (including gene editing with CRISPR cas9)--all in an easy-to understand book.

Carbohydrate Counting: Traditional Filipino Food Lists For Management And Prevention Of Diabetes Mellitus, Ashwini Wagle

Open Educational Resources

The Carbohydrate Counting tool was created to address the specific dietary needs of the Filipino population. It is an original intellectual work by Ashwini Wagle, Ed.D., MS, RD, Chair of the Department of Nutrition, Food Science, and Packaging at San Jose State University (SJSU).

The development of this tool was made possible through the collaboration and support of several contributors. Serena Starr, MS; Justine Martinez Cuaresma, MS, RD; Nazli Goudarzi, MS; Leah Olaivar; and Joe Johnston—a graduate student in the Department—played integral roles in the project. Their contributions included verifying the authenticity of traditional foods, designing culturally appropriate meal plans, …

Understanding Food Insecurity Among International Students At Ohio University, Kyle Butler, Joshua Osondu

Sustainable Living Hub Reports and Publications

Recently, food insecurity has emerged as a concern among the student body of Ohio University (OHIO), particularly among its international graduate students. This survey study was undertaken to provide data to inform OHIO’s response to food insecurity among its international graduate students.